John W Elrod, Ph.D. - Publications

Affiliations: 
2012- Center for Translational Medicine Temple University, Philadelphia, PA, United States 
Area:
Molecular Biology, Physiology, Cardiology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yellamilli A, Ren Y, McElmurry RT, Lambert JP, Gross P, Mohsin S, Houser SR, Elrod JW, Tolar J, Garry DJ, van Berlo JH. Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32100368 DOI: 10.1096/fj.201902105R  0.48
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Elrod JW, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/s41418-017-0012-4  0.32
2017 Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, ... Elrod JW, et al. The mitochondrial Na(+)/Ca(2+) exchanger is essential for Ca(2+) homeostasis and viability. Nature. PMID 28445457 DOI: 10.1038/nature22082  0.48
2016 Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, ... ... Elrod JW, et al. MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics. Cell Reports. PMID 27184846 DOI: 10.1016/j.celrep.2016.04.050  0.32
2016 De Simone FI, Darbinian N, Amini S, Muniswamy M, White MK, Elrod JW, Datta PK, Langford D, Khalili K. HIV-1 Tat and Cocaine Impair Survival of Cultured Primary Neuronal Cells via a Mitochondrial Pathway. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 27032771 DOI: 10.1007/s11481-016-9669-6  0.32
2015 Pfluger PT, Kabra DG, Aichler M, Schriever SC, Pfuhlmann K, García VC, Lehti M, Weber J, Kutschke M, Rozman J, Elrod JW, Hevener AL, Feuchtinger A, Hrabě de Angelis M, Walch A, et al. Calcineurin Links Mitochondrial Elongation with Energy Metabolism. Cell Metabolism. PMID 26411342 DOI: 10.1016/j.cmet.2015.08.022  0.32
2015 Luongo TS, Lambert JP, Yuan A, Zhang X, Gross P, Song J, Shanmughapriya S, Gao E, Jain M, Houser SR, Koch WJ, Cheung JY, Madesh M, Elrod JW. The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition. Cell Reports. PMID 26119731 DOI: 10.1016/j.celrep.2015.06.017  0.32
2015 Accornero F, van Berlo JH, Correll RN, Elrod JW, Sargent MA, York A, Rabinowitz JE, Leask A, Molkentin JD. Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling. Molecular and Cellular Biology. 35: 2154-64. PMID 25870108 DOI: 10.1128/MCB.00199-15  0.32
2015 Hoffman NE, Miller BA, Wang J, Elrod JW, Rajan S, Gao E, Song J, Zhang XQ, Hirschler-Laszkiewicz I, Shanmughapriya S, Koch WJ, Feldman AM, Madesh M, Cheung JY. Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance. American Journal of Physiology. Heart and Circulatory Physiology. 308: H637-50. PMID 25576627 DOI: 10.1152/ajpheart.00720.2014  0.32
2014 Elrod JW, van Berlo JH. Unraveling the complexities of cardiac remodeling and hypertrophy - high-content screening and computational modeling. Journal of Molecular and Cellular Cardiology. 72: 360-3. PMID 24742541 DOI: 10.1016/j.yjmcc.2014.03.014  0.48
2014 King AL, Polhemus DJ, Bhushan S, Otsuka H, Kondo K, Nicholson CK, Bradley JM, Islam KN, Calvert JW, Tao YX, Dugas TR, Kelley EE, Elrod JW, Huang PL, Wang R, et al. Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. Proceedings of the National Academy of Sciences of the United States of America. 111: 3182-7. PMID 24516168 DOI: 10.1073/pnas.1321871111  0.32
2014 Hoffman NE, Chandramoorthy HC, Shanmughapriya S, Zhang XQ, Vallem S, Doonan PJ, Malliankaraman K, Guo S, Rajan S, Elrod JW, Koch WJ, Cheung JY, Madesh M. SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death. Molecular Biology of the Cell. 25: 936-47. PMID 24430870 DOI: 10.1091/mbc.E13-08-0502  0.32
2013 Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice. Elife. 2: e00772. PMID 23991283 DOI: 10.7554/eLife.00772  0.32
2013 Elrod JW, Molkentin JD. Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore. Circulation Journal : Official Journal of the Japanese Circulation Society. 77: 1111-22. PMID 23538482 DOI: DN/JST.JSTAGE/circj/CJ-13-0321  0.32
2012 Vagnozzi RJ, Hoffman NE, Elrod JW, Madesh M, Force T. Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease. Drug Discovery Today. Therapeutic Strategies. 9: e173-e182. PMID 24839450 DOI: 10.1016/j.ddstr.2013.12.001  0.32
2012 Goonasekera SA, Hammer K, Auger-Messier M, Bodi I, Chen X, Zhang H, Reiken S, Elrod JW, Correll RN, York AJ, Sargent MA, Hofmann F, Moosmang S, Marks AR, Houser SR, et al. Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice. The Journal of Clinical Investigation. 122: 280-90. PMID 22133878 DOI: 10.1172/JCI58227  0.32
2011 van Berlo JH, Elrod JW, Aronow BJ, Pu WT, Molkentin JD. Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 12331-6. PMID 21746915 DOI: 10.1073/pnas.1104499108  0.48
2010 Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. The Journal of Clinical Investigation. 120: 3680-7. PMID 20890047 DOI: 10.1172/JCI43171  0.32
2010 van Berlo JH, Elrod JW, van den Hoogenhof MM, York AJ, Aronow BJ, Duncan SA, Molkentin JD. The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circulation Research. 107: 1032-40. PMID 20705924 DOI: 10.1161/CIRCRESAHA.110.220764  0.32
2010 Calvert JW, Elston M, Nicholson CK, Gundewar S, Jha S, Elrod JW, Ramachandran A, Lefer DJ. Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. Circulation. 122: 11-9. PMID 20566952 DOI: 10.1161/CIRCULATIONAHA.109.920991  0.92
2009 Minamishima S, Bougaki M, Sips PY, Yu JD, Minamishima YA, Elrod JW, Lefer DJ, Bloch KD, Ichinose F. Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. Circulation. 120: 888-96. PMID 19704099 DOI: 10.1161/CIRCULATIONAHA.108.833491  0.92
2009 Calvert JW, Jha S, Gundewar S, Elrod JW, Ramachandran A, Pattillo CB, Kevil CG, Lefer DJ. Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circulation Research. 105: 365-74. PMID 19608979 DOI: 10.1161/CIRCRESAHA.109.199919  0.32
2009 Lorts A, Schwanekamp JA, Elrod JW, Sargent MA, Molkentin JD. Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair. Circulation Research. 104: e1-7. PMID 19038863 DOI: 10.1161/CIRCRESAHA.108.188649  0.32
2008 Elrod JW, Calvert JW, Gundewar S, Bryan NS, Lefer DJ. Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 105: 11430-5. PMID 18685092 DOI: 10.1073/pnas.0800700105  0.92
2008 Elrod JW, Harrell M, Flagg TP, Gundewar S, Magnuson MA, Nichols CG, Coetzee WA, Lefer DJ. Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation. 117: 1405-13. PMID 18316485 DOI: 10.1161/CIRCULATIONAHA.107.745539  0.32
2007 Bryan NS, Calvert JW, Elrod JW, Gundewar S, Ji SY, Lefer DJ. Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America. 104: 19144-9. PMID 18025468 DOI: 10.1073/pnas.0706579104  0.92
2007 Elrod JW, Calvert JW, Morrison J, Doeller JE, Kraus DW, Tao L, Jiao X, Scalia R, Kiss L, Szabo C, Kimura H, Chow CW, Lefer DJ. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 104: 15560-5. PMID 17878306 DOI: 10.1073/pnas.0705891104  0.92
2007 Gundewar S, Calvert JW, Elrod JW, Lefer DJ. Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2462-71. PMID 17630348 DOI: 10.1152/ajpheart.00392.2007  0.92
2007 Elrod JW, Greer JJ, Lefer DJ. Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway. American Journal of Physiology. Heart and Circulatory Physiology. 292: H342-7. PMID 16951048 DOI: 10.1152/ajpheart.00306.2006  0.92
2006 Duranski MR, Elrod JW, Calvert JW, Bryan NS, Feelisch M, Lefer DJ. Genetic overexpression of eNOS attenuates hepatic ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2980-6. PMID 16877550 DOI: 10.1152/ajpheart.01173.2005  0.92
2006 Greer JJ, Kakkar AK, Elrod JW, Watson LJ, Jones SP, Lefer DJ. Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2743-51. PMID 16844920 DOI: 10.1152/ajpheart.00347.2006  0.92
2006 Elrod JW, Duranski MR, Langston W, Greer JJ, Tao L, Dugas TR, Kevil CG, Champion HC, Lefer DJ. eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling. Circulation Research. 99: 78-85. PMID 16763164 DOI: 10.1161/01.RES.0000231306.03510.77  0.32
2006 Elrod JW, Greer JJ, Bryan NS, Langston W, Szot JF, Gebregzlabher H, Janssens S, Feelisch M, Lefer DJ. Cardiomyocyte-specific overexpression of NO synthase-3 protects against myocardial ischemia-reperfusion injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1517-23. PMID 16645153 DOI: 10.1161/01.ATV.0000224324.52466.e6  0.92
2005 Elrod JW, Laroux FS, Houghton J, Carpenter A, Ando T, Jennings MH, Grisham M, Walker N, Alexander JS. DSS-induced colitis is exacerbated in STAT-6 knockout mice. Inflammatory Bowel Diseases. 11: 883-9. PMID 16189417 DOI: 10.1097/01.MIB.0000182871.76434.57  0.32
2005 Mori M, Stokes KY, Vowinkel T, Watanabe N, Elrod JW, Harris NR, Lefer DJ, Hibi T, Granger DN. Colonic blood flow responses in experimental colitis: time course and underlying mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G1024-9. PMID 16081759 DOI: 10.1152/ajpgi.00247.2005  0.32
2005 Elrod JW, Lefer DJ. The effects of statins on endothelium, inflammation and cardioprotection. Drug News & Perspectives. 18: 229-36. PMID 16034478 DOI: 10.1358/dnp.2005.18.4.908656  0.92
2005 Sasaki M, Jordan P, Welbourne T, Minagar A, Joh T, Itoh M, Elrod JW, Alexander JS. Troglitazone, a PPAR-gamma activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-alpha. Bmc Physiology. 5: 3. PMID 15694007 DOI: 10.1186/1472-6793-5-3  0.32
2004 Sasaki M, Elrod JW, Jordan P, Itoh M, Joh T, Minagar A, Alexander JS. CYP450 dietary inhibitors attenuate TNF-alpha-stimulated endothelial molecule expression and leukocyte adhesion. American Journal of Physiology. Cell Physiology. 286: C931-9. PMID 15001427 DOI: 10.1152/ajpcell.00351.2003  0.32
2004 Jawahar A, Jawahar LL, Nanda A, Sharp CD, Warren A, Elrod JW, Jennings M, Alexander JS, Minagar A. Stereotactic radiosurgery using the Leksell Gamma Knife: current trends and future directives. Frontiers in Bioscience : a Journal and Virtual Library. 9: 932-8. PMID 14766419  0.32
2003 Oshima T, Blaschuk O, Gour B, Symonds M, Elrod JW, Sasaki M, Jackson TH, Alexander JS. Tight junction peptide antagonists enhance neutrophil trans-endothelial chemotaxis. Life Sciences. 73: 1729-40. PMID 12875904 DOI: 10.1016/S0024-3205(03)00511-3  0.32
2003 Sharp CD, Jawahar A, Warren AC, Elrod JW, Nanda A, Alexander JS, Rutka JT, Khurana VG, Pollock BE, Piepmeier JM, Kondziolka D. Gamma knife irradiation increases cerebral endothelial expression of intercellular adhesion molecule 1 and E-selectin Neurosurgery. 53: 154-161. PMID 12823884  0.32
2003 Sasaki M, Bharwani S, Jordan P, Joh T, Manas K, Warren A, Harada H, Carter P, Elrod JW, Wolcott M, Grisham MB, Alexander JS. The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis. The Journal of Pharmacology and Experimental Therapeutics. 305: 78-85. PMID 12649355 DOI: 10.1124/jpet.102.044099  0.32
2002 Blaschuk OW, Oshima T, Gour BJ, Symonds JM, Park JH, Kevil CG, Trocha SD, Michaud S, Okayama N, Elrod JW, Alexander JS, Sasaki M. Identification of an occludin cell adhesion recognition sequence. Inflammation. 26: 193-8. PMID 12184633 DOI: 10.1023/A:1016571830091  0.32
2002 Alexander JS, Elrod JW. Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation Journal of Anatomy. 200: 561-574. PMID 12162724 DOI: 10.1046/j.1469-7580.2002.00057.x  0.32
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