John W Elrod, Ph.D. - Publications

Affiliations: 
2012- Center for Translational Medicine Temple University, Philadelphia, PA, United States 
Area:
Molecular Biology, Physiology, Cardiology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li Z, Xia H, Sharp TE, LaPenna KB, Katsouda A, Elrod JW, Pfeilschifter J, Beck KF, Xu S, Xian M, Goodchild TT, Papapetropoulos A, Lefer DJ. Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. Circulation Research. 132: 154-166. PMID 36575984 DOI: 10.1161/CIRCRESAHA.122.321326  0.495
2022 Li Z, Xia H, Sharp TE, LaPenna KB, Elrod JW, Casin KM, Liu K, Calvert JW, Chau VQ, Salloum FN, Xu S, Xian M, Nagahara N, Goodchild TT, Lefer DJ. Mitochondrial HS Regulates BCAA Catabolism in Heart Failure. Circulation Research. 101161CIRCRESAHA1213. PMID 35701874 DOI: 10.1161/CIRCRESAHA.121.319817  0.544
2022 Garbincius JF, Luongo TS, Jadiya P, Hildebrand AN, Kolmetzky DW, Mangold AS, Roy R, Ibetti J, Nwokedi M, Koch WJ, Elrod JW. Enhanced NCLX-dependent mitochondrial Ca efflux attenuates pathological remodeling in heart failure. Journal of Molecular and Cellular Cardiology. 167: 52-66. PMID 35358843 DOI: 10.1016/j.yjmcc.2022.03.001  0.302
2022 Lazaropoulos MP, Elrod JW. Mitochondria in Pathological Cardiac Remodeling. Current Opinion in Physiology. 25. PMID 35274068 DOI: 10.1016/j.cophys.2022.100489  0.324
2021 Joseph LC, Reyes MV, Homan EA, Gowen B, Avula UMR, Goulbourne CN, Wan EY, Elrod JW, Morrow JP. The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet. Scientific Reports. 11: 17808. PMID 34497331 DOI: 10.1038/s41598-021-97449-3  0.306
2020 Xia H, Li Z, Sharp TE, Polhemus DJ, Carnal J, Moles KH, Tao YX, Elrod J, Pfeilschifter J, Beck KF, Lefer DJ. Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury. Journal of the American Heart Association. e017544. PMID 32990120 DOI: 10.1161/JAHA.120.017544  0.523
2020 Tomar D, Elrod JW. Metabolite regulation of the mitochondrial calcium uniporter channel. Cell Calcium. 92: 102288. PMID 32956979 DOI: 10.1016/J.Ceca.2020.102288  0.324
2020 Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antolín A, ... ... Elrod JW, et al. Na controls hypoxic signalling by the mitochondrial respiratory chain. Nature. PMID 32728214 DOI: 10.1038/S41586-020-2551-Y  0.334
2020 Gibb AA, Lazaropoulos MP, Elrod JW. Myofibroblasts and Fibrosis: Mitochondrial and Metabolic Control of Cellular Differentiation. Circulation Research. 127: 427-447. PMID 32673537 DOI: 10.1161/Circresaha.120.316958  0.409
2020 Garbincius JF, Luongo TS, Elrod JW. The debate continues - What is the role of MCU and mitochondrial calcium uptake in the heart? Journal of Molecular and Cellular Cardiology. PMID 32353353 DOI: 10.1016/J.Yjmcc.2020.04.029  0.396
2020 Yellamilli A, Ren Y, McElmurry RT, Lambert JP, Gross P, Mohsin S, Houser SR, Elrod JW, Tolar J, Garry DJ, van Berlo JH. Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32100368 DOI: 10.1096/Fj.201902105R  0.351
2019 Ahmad F, Tomar D, Aryal A C S, Elmoselhi AB, Thomas M, Elrod JW, Tilley DG, Force T. Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165609. PMID 31743747 DOI: 10.1016/J.Bbadis.2019.165609  0.436
2019 Lombardi AA, Gibb AA, Arif E, Kolmetzky DW, Tomar D, Luongo TS, Jadiya P, Murray EK, Lorkiewicz PK, Hajnóczky G, Murphy E, Arany ZP, Kelly DP, Margulies KB, Hill BG, ... Elrod JW, et al. Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation. Nature Communications. 10: 4509. PMID 31586055 DOI: 10.1038/S41467-019-12103-X  0.337
2019 Lambert JP, Luongo TS, Tomar D, Jadiya P, Gao E, Zhang X, Lucchese AM, Kolmetzky DW, Shah NS, Elrod JW. MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress. Circulation. PMID 31533452 DOI: 10.1161/Circulationaha.118.037968  0.406
2019 Bahmed K, Lin CR, Simborio H, Karim L, Aksoy M, Kelsen S, Tomar D, Muniswamy M, Elrod JW, Messier E, Mason RJ, Unterwald EM, Eisenstein TK, Criner GJ, Kosmider B. The role of DJ-1 in human primary alveolar type II cell injury induced by e-cigarette aerosol. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31313616 DOI: 10.1152/Ajplung.00567.2018  0.372
2019 Wang Y, He S, Liu Y, Hooper R, Yu H, Tian Y, Tien B, Schultz BM, Elrod JW, Soboloff J, Zhang Y. Artesunate Inhibits Graft-Versus-Host Disease in Mice Via a Mechanism of Inducing Mitochondrial Calcium Overloading in Activated T Cells Blood. 134: 4432-4432. DOI: 10.1182/Blood-2019-131115  0.322
2019 Lambert JP, Luongo TS, Tomar D, Jadiya P, Gao E, Zhang X, Lucchese AM, Kolmetzky DW, Shah N, Elrod JW. Abstract 857: MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel During Cardiac Stress to Limit Mitochondrial Calcium Overload Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.857  0.319
2019 Garbincius JF, Luongo TS, Kolmetzky DW, Hildebrand AN, Elrod JW. Abstract 851: NCLX Expression Attenuates Pathological Remodeling in Experimental Cardiac Hypertrophy and Non-ischemic Heart Failure Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.851  0.365
2019 Murashige DS, Jang C, Neinast MD, Elrod JW, Kelly DP, Rabinowitz JD, Frankel DS, Arany ZP. Abstract 562: Comprehensive Arteriovenous Metabolomics in the Human Heart Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.562  0.308
2019 Gibb AA, Lombardi AA, Murray EK, Tan Y, Lorkiewicz PK, Huynh AT, Kolmetzky DW, Arany Z, Kelly DP, Margulies KB, Hill BG, Elrod JW. Abstract 517: Glutaminolysis is Required to Initiate Myofibroblast Differentiation and Persistence During Stress Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.517  0.353
2018 De La Fuente S, Lambert JP, Nichtova Z, Fernandez Sanz C, Elrod JW, Sheu SS, Csordás G. Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart. Cell Reports. 24: 3099-3107.e4. PMID 30231993 DOI: 10.1016/J.Celrep.2018.08.040  0.362
2018 Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Reports. 23: 3710-3720.e8. PMID 29949756 DOI: 10.1016/J.Celrep.2018.06.002  0.325
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Elrod JW, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.464
2018 Lambert JP, Luongo TS, Jadiya P, Gao E, Lucchesee AM, Zhang X, Kolmetzky DW, Shah N, Elrod JW. Abstract 539: MCUB Regulates the Macromolecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Ischemic Cardiac Injury Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.539  0.343
2018 Guo S, Lambert J, Song J, Carter R, Lucchese AM, Gao E, Cheung J, Elrod J, Tilley D. Abstract 423: Cardiomyocyte-Specific Epidermal Growth Factor Receptor Deletion Differentially Alters Cardiac Contractility and Remodeling During Physiologic versus Pathologic Development Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.423  0.311
2018 Garbincius JF, Luongo TS, Lambert JP, Elrod JW. Abstract 277: Enhanced Mitochondrial Calcium Uptake Promotes Deleterious Remodeling and Impaired Left Ventricular Function During Chronic Adrenergic Stimulation Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.277  0.312
2018 De la Fuente S, Fernadez-Sanz C, Lambert JP, Elrod JW, Sheu S, Csordas G. The Spatial Distribution of the Na+/Ca2+ Exchanger in Cardiac Mitochondria Enhances the Efficincy of the Mitochondrial Ca2+ Signal Generation Biophysical Journal. 114: 659a. DOI: 10.1016/J.Bpj.2017.11.3561  0.321
2017 Lombardi AA, Elrod JW. Mediating ER-mitochondrial cross-talk. Science (New York, N.Y.). 358: 591-592. PMID 29097535 DOI: 10.1126/Science.Aaq0141  0.316
2017 Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, ... Elrod JW, et al. The mitochondrial Na(+)/Ca(2+) exchanger is essential for Ca(2+) homeostasis and viability. Nature. PMID 28445457 DOI: 10.1038/Nature22082  0.593
2017 La Fuente SD, Fernandez-Sanz C, Lambert J, Elrod J, Sheu S, Csordas G. The spatial distribution of the Na + /Ca 2+ exchanger in cardiac mitochondria enhances the efficiency of mitochondrial Ca 2+ signal generation Journal of Molecular and Cellular Cardiology. 112: 169. DOI: 10.1016/J.Yjmcc.2017.07.114  0.319
2017 Lombardi AA, Arif E, Luongo TS, Elrod JW. Genetic Ablation of Fibroblast Mitochondrial Calcium Uptake Increases Myofibroblast Transdifferentiation and Exacerbates Fibrosis in Myocardial Infarction Biophysical Journal. 112: 96a. DOI: 10.1016/J.Bpj.2016.11.558  0.439
2017 Jadiya P, Lombardi AA, Lambert JP, Luongo TS, Chu J, Praticò D, Elrod JW. Genetic Rescue of Mitochondrial Calcium Efflux in Alzheimer's Disease Preserves Mitochondrial Function and Protects against Neuronal Cell Death Biophysical Journal. 112: 445a. DOI: 10.1016/J.Bpj.2016.11.2383  0.317
2016 Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, ... ... Elrod JW, et al. MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics. Cell Reports. PMID 27184846 DOI: 10.1016/J.Celrep.2016.04.050  0.341
2015 Sato PY, Chuprun JK, Ibetti J, Cannavo A, Drosatos K, Elrod JW, Koch WJ. GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels. Journal of Molecular and Cellular Cardiology. PMID 26506135 DOI: 10.1016/J.Yjmcc.2015.10.002  0.397
2015 Pfluger PT, Kabra DG, Aichler M, Schriever SC, Pfuhlmann K, García VC, Lehti M, Weber J, Kutschke M, Rozman J, Elrod JW, Hevener AL, Feuchtinger A, Hrabě de Angelis M, Walch A, et al. Calcineurin Links Mitochondrial Elongation with Energy Metabolism. Cell Metabolism. PMID 26411342 DOI: 10.1016/J.Cmet.2015.08.022  0.486
2015 Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M, Leonard NJ, Stolakis RS, Wolfers MP, ... ... Elrod JW, et al. SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore. Molecular Cell. 60: 47-62. PMID 26387735 DOI: 10.1016/J.Molcel.2015.08.009  0.338
2015 Luongo TS, Lambert JP, Yuan A, Zhang X, Gross P, Song J, Shanmughapriya S, Gao E, Jain M, Houser SR, Koch WJ, Cheung JY, Madesh M, Elrod JW. The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition. Cell Reports. PMID 26119731 DOI: 10.1016/J.Celrep.2015.06.017  0.431
2015 Lombardi AA, Elrod JW. mtDNA damage in the development of heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 309: H393-5. PMID 26092989 DOI: 10.1152/Ajpheart.00475.2015  0.35
2015 Khan M, Nickoloff E, Abramova T, Johnson J, Verma SK, Krishnamurthy P, Mackie AR, Vaughan E, Garikipati VN, Benedict C, Ramirez V, Lambers E, Ito A, Gao E, Misener S, ... ... Elrod J, et al. Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction. Circulation Research. 117: 52-64. PMID 25904597 DOI: 10.1161/Circresaha.117.305990  0.33
2015 Accornero F, van Berlo JH, Correll RN, Elrod JW, Sargent MA, York A, Rabinowitz JE, Leask A, Molkentin JD. Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling. Molecular and Cellular Biology. 35: 2154-64. PMID 25870108 DOI: 10.1128/Mcb.00199-15  0.525
2015 Hoffman NE, Miller BA, Wang J, Elrod JW, Rajan S, Gao E, Song J, Zhang XQ, Hirschler-Laszkiewicz I, Shanmughapriya S, Koch WJ, Feldman AM, Madesh M, Cheung JY. Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance. American Journal of Physiology. Heart and Circulatory Physiology. 308: H637-50. PMID 25576627 DOI: 10.1152/Ajpheart.00720.2014  0.435
2015 Polhemus DJ, Elrod JW, Giordano T, Goodchild TT, Lefer DJ. Clinical evidence of hydrogen sulfide-mediated elevation in circulating nitrite Nitric Oxide. 47: S28. DOI: 10.1016/J.Niox.2015.02.067  0.488
2014 Elrod JW, van Berlo JH. Unraveling the complexities of cardiac remodeling and hypertrophy - high-content screening and computational modeling. Journal of Molecular and Cellular Cardiology. 72: 360-3. PMID 24742541 DOI: 10.1016/J.Yjmcc.2014.03.014  0.364
2014 King AL, Polhemus DJ, Bhushan S, Otsuka H, Kondo K, Nicholson CK, Bradley JM, Islam KN, Calvert JW, Tao YX, Dugas TR, Kelley EE, Elrod JW, Huang PL, Wang R, et al. Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. Proceedings of the National Academy of Sciences of the United States of America. 111: 3182-7. PMID 24516168 DOI: 10.1073/Pnas.1321871111  0.573
2014 Hoffman NE, Chandramoorthy HC, Shanmughapriya S, Zhang XQ, Vallem S, Doonan PJ, Malliankaraman K, Guo S, Rajan S, Elrod JW, Koch WJ, Cheung JY, Madesh M. SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death. Molecular Biology of the Cell. 25: 936-47. PMID 24430870 DOI: 10.1091/Mbc.E13-08-0502  0.343
2014 Polhemus DJ, Otsuka H, Bhushan S, Islam KN, Bradley JM, Elrod JW, Lefer DJ. P83 Nitric Oxide. 39: S40-S41. DOI: 10.1016/J.Niox.2014.03.133  0.556
2014 Gojon G, Gojon G, Lefer DJ, Elrod JW, Giordano T. S5-4 Phase I, heart failure clinical trial to evaluate the safety of SG1002 – A novel hydrogen sulfide donor Nitric Oxide. 39: S6-S7. DOI: 10.1016/J.Niox.2014.03.024  0.544
2013 Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice. Elife. 2: e00772. PMID 23991283 DOI: 10.7554/Elife.00772  0.498
2013 Elrod JW, Molkentin JD. Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore. Circulation Journal : Official Journal of the Japanese Circulation Society. 77: 1111-22. PMID 23538482 DOI: 10.1253/Circj.Cj-13-0321  0.509
2013 Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Author response: Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice Elife. DOI: 10.7554/Elife.00772.020  0.51
2012 Vagnozzi RJ, Hoffman NE, Elrod JW, Madesh M, Force T. Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease. Drug Discovery Today. Therapeutic Strategies. 9: e173-e182. PMID 24839450 DOI: 10.1016/J.Ddstr.2013.12.001  0.404
2012 Goonasekera SA, Hammer K, Auger-Messier M, Bodi I, Chen X, Zhang H, Reiken S, Elrod JW, Correll RN, York AJ, Sargent MA, Hofmann F, Moosmang S, Marks AR, Houser SR, et al. Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice. The Journal of Clinical Investigation. 122: 280-90. PMID 22133878 DOI: 10.1172/Jci58227  0.555
2011 van Berlo JH, Elrod JW, Aronow BJ, Pu WT, Molkentin JD. Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 12331-6. PMID 21746915 DOI: 10.1073/Pnas.1104499108  0.557
2010 Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. The Journal of Clinical Investigation. 120: 3680-7. PMID 20890047 DOI: 10.1172/Jci43171  0.577
2010 van Berlo JH, Elrod JW, van den Hoogenhof MM, York AJ, Aronow BJ, Duncan SA, Molkentin JD. The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circulation Research. 107: 1032-40. PMID 20705924 DOI: 10.1161/Circresaha.110.220764  0.481
2010 Calvert JW, Elston M, Nicholson CK, Gundewar S, Jha S, Elrod JW, Ramachandran A, Lefer DJ. Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. Circulation. 122: 11-9. PMID 20566952 DOI: 10.1161/Circulationaha.109.920991  0.572
2010 Calvert JW, Gundewar S, Elrod J, Lefer DJ. HYDROGEN SULFIDE CONFERS CARDIOPROTECTION IN THE SETTING OF DIABETES Journal of the American College of Cardiology. 55: A116.E1082. DOI: 10.1016/S0735-1097(10)61083-2  0.467
2010 Calvert JW, Elston M, Jha S, Gundewar S, Aragon JP, Grinsfelder DB, Ramachandran A, Elrod JW, Lefer DJ. HYDROGEN SULFIDE THERAPY ATTENUATES ISCHEMIA-INDUCED HEART FAILURE VIA NRF2 AND NRF1 SIGNALING Journal of the American College of Cardiology. 55: A20.E186. DOI: 10.1016/S0735-1097(10)60187-8  0.563
2009 Minamishima S, Bougaki M, Sips PY, Yu JD, Minamishima YA, Elrod JW, Lefer DJ, Bloch KD, Ichinose F. Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. Circulation. 120: 888-96. PMID 19704099 DOI: 10.1161/Circulationaha.108.833491  0.564
2009 Calvert JW, Jha S, Gundewar S, Elrod JW, Ramachandran A, Pattillo CB, Kevil CG, Lefer DJ. Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circulation Research. 105: 365-74. PMID 19608979 DOI: 10.1161/Circresaha.109.199919  0.512
2009 Lorts A, Schwanekamp JA, Elrod JW, Sargent MA, Molkentin JD. Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair. Circulation Research. 104: e1-7. PMID 19038863 DOI: 10.1161/Circresaha.108.188649  0.574
2008 Elrod JW, Calvert JW, Gundewar S, Bryan NS, Lefer DJ. Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 105: 11430-5. PMID 18685092 DOI: 10.1073/Pnas.0800700105  0.594
2008 Elrod JW, Harrell M, Flagg TP, Gundewar S, Magnuson MA, Nichols CG, Coetzee WA, Lefer DJ. Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation. 117: 1405-13. PMID 18316485 DOI: 10.1161/Circulationaha.107.745539  0.546
2007 Bryan NS, Calvert JW, Elrod JW, Gundewar S, Ji SY, Lefer DJ. Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America. 104: 19144-9. PMID 18025468 DOI: 10.1073/Pnas.0706579104  0.557
2007 Elrod JW, Calvert JW, Morrison J, Doeller JE, Kraus DW, Tao L, Jiao X, Scalia R, Kiss L, Szabo C, Kimura H, Chow CW, Lefer DJ. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 104: 15560-5. PMID 17878306 DOI: 10.1073/Pnas.0705891104  0.58
2007 Gundewar S, Calvert JW, Elrod JW, Lefer DJ. Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2462-71. PMID 17630348 DOI: 10.1152/Ajpheart.00392.2007  0.571
2007 Elrod JW, Greer JJ, Lefer DJ. Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway. American Journal of Physiology. Heart and Circulatory Physiology. 292: H342-7. PMID 16951048 DOI: 10.1152/Ajpheart.00306.2006  0.579
2006 Duranski MR, Elrod JW, Calvert JW, Bryan NS, Feelisch M, Lefer DJ. Genetic overexpression of eNOS attenuates hepatic ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2980-6. PMID 16877550 DOI: 10.1152/Ajpheart.01173.2005  0.562
2006 Greer JJ, Kakkar AK, Elrod JW, Watson LJ, Jones SP, Lefer DJ. Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2743-51. PMID 16844920 DOI: 10.1152/Ajpheart.00347.2006  0.563
2006 Elrod JW, Duranski MR, Langston W, Greer JJ, Tao L, Dugas TR, Kevil CG, Champion HC, Lefer DJ. eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling. Circulation Research. 99: 78-85. PMID 16763164 DOI: 10.1161/01.Res.0000231306.03510.77  0.532
2006 Elrod JW, Greer JJ, Bryan NS, Langston W, Szot JF, Gebregzlabher H, Janssens S, Feelisch M, Lefer DJ. Cardiomyocyte-specific overexpression of NO synthase-3 protects against myocardial ischemia-reperfusion injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1517-23. PMID 16645153 DOI: 10.1161/01.Atv.0000224324.52466.E6  0.546
2005 Mori M, Stokes KY, Vowinkel T, Watanabe N, Elrod JW, Harris NR, Lefer DJ, Hibi T, Granger DN. Colonic blood flow responses in experimental colitis: time course and underlying mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G1024-9. PMID 16081759 DOI: 10.1152/Ajpgi.00247.2005  0.516
2005 Elrod JW, Lefer DJ. The effects of statins on endothelium, inflammation and cardioprotection. Drug News & Perspectives. 18: 229-36. PMID 16034478 DOI: 10.1358/Dnp.2005.18.4.908656  0.525
2005 Sharp CD, Houghton J, Elrod JW, Warren A, Jackson TH, Jawahar A, Nanda A, Minagar A, Alexander JS. N-methyl-D-aspartate receptor activation in human cerebral endothelium promotes intracellular oxidant stress. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1893-9. PMID 15576430 DOI: 10.1152/Ajpheart.01110.2003  0.317
2003 Sasaki M, Bharwani S, Jordan P, Elrod JW, Grisham MB, Jackson TH, Lefer DJ, Alexander JS. Increased disease activity in eNOS-deficient mice in experimental colitis. Free Radical Biology & Medicine. 35: 1679-87. PMID 14680690 DOI: 10.1016/J.Freeradbiomed.2003.09.016  0.551
2003 Sasaki M, Bharwani S, Jordan P, Joh T, Manas K, Warren A, Harada H, Carter P, Elrod JW, Wolcott M, Grisham MB, Alexander JS. The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis. The Journal of Pharmacology and Experimental Therapeutics. 305: 78-85. PMID 12649355 DOI: 10.1124/Jpet.102.044099  0.328
2003 Sasaki M, Ostanin D, Elrod JW, Oshima T, Jordan P, Itoh M, Joh T, Minagar A, Alexander JS. TNF-alpha -induced endothelial cell adhesion molecule expression is cytochrome P-450 monooxygenase dependent. American Journal of Physiology. Cell Physiology. 284: C422-8. PMID 12388057 DOI: 10.1152/Ajpcell.00271.2002  0.311
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