| Year |
Citation |
Score |
| 2023 |
LaPenna KB, Li Z, Doiron JE, Sharp TE, Xia H, Moles K, Koul K, Wang JS, Polhemus DJ, Goodchild TT, Patel RB, Shah SJ, Lefer DJ. Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine Model. Journal of the American Heart Association. e028480. PMID 36752224 DOI: 10.1161/JAHA.122.028480 |
0.303 |
|
| 2022 |
Li Z, Xia H, Sharp TE, LaPenna KB, Katsouda A, Elrod JW, Pfeilschifter J, Beck KF, Xu S, Xian M, Goodchild TT, Papapetropoulos A, Lefer DJ. Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. Circulation Research. 132: 154-166. PMID 36575984 DOI: 10.1161/CIRCRESAHA.122.321326 |
0.587 |
|
| 2022 |
Li Z, Xia H, Sharp TE, LaPenna KB, Elrod JW, Casin KM, Liu K, Calvert JW, Chau VQ, Salloum FN, Xu S, Xian M, Nagahara N, Goodchild TT, Lefer DJ. Mitochondrial HS Regulates BCAA Catabolism in Heart Failure. Circulation Research. 101161CIRCRESAHA1213. PMID 35701874 DOI: 10.1161/CIRCRESAHA.121.319817 |
0.585 |
|
| 2020 |
Xia H, Li Z, Sharp TE, Polhemus DJ, Carnal J, Moles KH, Tao YX, Elrod J, Pfeilschifter J, Beck KF, Lefer DJ. Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury. Journal of the American Heart Association. e017544. PMID 32990120 DOI: 10.1161/JAHA.120.017544 |
0.615 |
|
| 2020 |
Organ CL, Li Z, Sharp TE, Polhemus DJ, Gupta N, Goodchild TT, Tang WHW, Hazen SL, Lefer DJ. Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure. Journal of the American Heart Association. e016223. PMID 32390485 DOI: 10.1161/Jaha.119.016223 |
0.384 |
|
| 2020 |
Peleli M, Bibli SI, Li Z, Chatzianastasiou A, Varela A, Katsouda A, Zukunft S, Bucci M, Vellecco V, Davos CH, Nagahara N, Cirino G, Fleming I, Lefer DJ, Papapetropoulos A. Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. Biochemical Pharmacology. 113833. PMID 32027885 DOI: 10.1016/J.Bcp.2020.113833 |
0.388 |
|
| 2020 |
Papanicolaou KN, Ashok D, Liu T, Bauer TM, Sun J, Li Z, da Costa E, D'Orleans CC, Nathan S, Lefer DJ, Murphy E, Paolocci N, Foster DB, O'Rourke B. Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP. Journal of Molecular and Cellular Cardiology. PMID 32004507 DOI: 10.1016/J.Yjmcc.2020.01.010 |
0.441 |
|
| 2020 |
Xia H, Li Z, Nagahara N, Carnal J, Lefer D. Genetic Knockout of 3‐Mercaptopyruvate Sulfurtransferase Increases Acute Myocardial Ischemia/Reperfusion Injury in Aged Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04685 |
0.396 |
|
| 2020 |
Hidalgo HA, Gao J, LaPenna K, Haydel A, Kapusta D, Goodchild T, Lefer D. Radiofrequency Renal Denervation (RF‐RDN) Ameliorates the Severity of Heart Failure with Preserved Ejection Fraction (HFpEF) The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04405 |
0.307 |
|
| 2020 |
LaPenna KB, Hidalgo HA, Gao J, Haydel A, Kapusta D, Goodchild T, Lefer DJ. Development and Characterization of a Novel Small Animal Model of Heart Failure with Preserved Ejection Fraction The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04357 |
0.322 |
|
| 2019 |
Kar S, Shahshahan HR, Hackfort BT, Yadav SK, Yadav R, Kambis TN, Lefer DJ, Mishra PK. Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy. Antioxidants (Basel, Switzerland). 8. PMID 31835893 DOI: 10.3390/Antiox8120638 |
0.381 |
|
| 2019 |
Sharp TE, Lefer DJ, Houser SR. Cardiometabolic Heart Failure and HFpEF: Still Chasing Unicorns. Jacc. Basic to Translational Science. 4: 422-424. PMID 31312764 DOI: 10.1016/J.Jacbts.2019.05.003 |
0.319 |
|
| 2019 |
Kar S, Shahshahan HR, Kambis TN, Yadav SK, Li Z, Lefer DJ, Mishra PK. Hydrogen Sulfide Ameliorates Homocysteine-Induced Cardiac Remodeling and Dysfunction. Frontiers in Physiology. 10: 598. PMID 31178749 DOI: 10.3389/Fphys.2019.00598 |
0.403 |
|
| 2019 |
Rushing AM, Donnarumma E, Polhemus DJ, Au KR, Victoria SE, Schumacher JD, Li Z, Jenkins JS, Lefer DJ, Goodchild TT. Effects of a novel hydrogen sulfide prodrug in a porcine model of acute limb ischemia. Journal of Vascular Surgery. PMID 30777693 DOI: 10.1016/J.Jvs.2018.08.172 |
0.342 |
|
| 2019 |
Polhemus DJ, Trivedi RK, Sharp TE, Li Z, Goodchild TT, Scarborough A, de Couto G, Marbán E, Lefer DJ. Repeated cell transplantation and adjunct renal denervation in ischemic heart failure: exploring modalities for improving cell therapy efficacy. Basic Research in Cardiology. 114: 9. PMID 30656501 DOI: 10.1007/S00395-019-0718-1 |
0.352 |
|
| 2019 |
Jones SP, Lefer DJ. Myocardial Reperfusion Injury: Insights Gained from Gene-Targeted Mice. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 15: 303-308. PMID 11390931 DOI: 10.1152/physiologyonline.2000.15.6.303 |
0.307 |
|
| 2018 |
Lefer DJ, Sharp TE. Angiotensin Receptor-Neprilysin Inhibitors Emerge as Potential Treatment for Acute Myocardial Infarction. Journal of the American College of Cardiology. 72: 2357-2359. PMID 30384892 DOI: 10.1016/J.Jacc.2018.08.2170 |
0.327 |
|
| 2018 |
Li Z, Polhemus DJ, Lefer DJ. Evolution of Hydrogen Sulfide Therapeutics to Treat Cardiovascular Disease. Circulation Research. 123: 590-600. PMID 30355137 DOI: 10.1161/Circresaha.118.311134 |
0.324 |
|
| 2018 |
Lefer D. Redox Pioneer: Professor Hideo Kimura. Antioxidants & Redox Signaling. 30: 1699-1708. PMID 30234368 DOI: 10.1089/Ars.2018.7618 |
0.323 |
|
| 2018 |
Trivedi RK, Polhemus DJ, Li Z, Yoo D, Koiwaya H, Scarborough A, Goodchild TT, Lefer DJ. Combined Angiotensin Receptor-Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure. Journal of the American Heart Association. 7. PMID 29502102 DOI: 10.1161/Jaha.117.008268 |
0.378 |
|
| 2018 |
Shimizu Y, Polavarapu R, Eskla KL, Nicholson CK, Koczor CA, Wang R, Lewis W, Shiva S, Lefer DJ, Calvert JW. Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK. Journal of Molecular and Cellular Cardiology. 116: 29-40. PMID 29408195 DOI: 10.1016/J.Yjmcc.2018.01.011 |
0.302 |
|
| 2018 |
Sharp T, Polhemus D, Li Z, Spaletra P, Reilly J, Jenkins J, White C, Lefer D, Goodchild T. TCT-30 Renal Denervation Improves Cardiac Function in a Swine Model of Heart Failure Journal of the American College of Cardiology. 72: B14. DOI: 10.1016/J.Jacc.2018.08.1111 |
0.417 |
|
| 2017 |
Bradley JM, Li Z, Organ CL, Polhemus DJ, Otsuka H, Bhushan S, Gorodnya OM, Ruchko M, Gillespie MN, Wilson GL, Lefer DJ. A Novel Mitochondrial DNA Repair Enzyme Attenuates Maladaptive Remodeling and Preserves Cardiac Function in Heart Failure. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00515.2017. PMID 29101177 DOI: 10.1152/Ajpheart.00515.2017 |
0.37 |
|
| 2017 |
Polhemus DJ, Trivedi RK, Gao J, Li Z, Scarborough AL, Goodchild TT, Varner KJ, Xia H, Smart FW, Kapusta DR, Lefer DJ. Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney. Journal of the American College of Cardiology. 70: 2139-2153. PMID 29050562 DOI: 10.1016/J.Jacc.2017.08.056 |
0.405 |
|
| 2017 |
Kimura Y, Koike S, Shibuya N, Lefer D, Ogasawara Y, Kimura H. 3-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S. Scientific Reports. 7: 10459. PMID 28874874 DOI: 10.1038/S41598-017-11004-7 |
0.338 |
|
| 2017 |
Zheng Y, Yu B, Li Z, Yuan Z, Lefer DJ, Wang B, Wang S, Organ CL, Trivedi RK. A Novel Esterase-sensitive Prodrug Approach for Controllable Delivery of Persulfide Species. Angewandte Chemie (International Ed. in English). PMID 28700817 DOI: 10.1002/Anie.201704117 |
0.349 |
|
| 2017 |
Lefer DJ, Marbán E. Is Cardioprotection Dead? Circulation. 136: 98-109. PMID 28674094 DOI: 10.1161/Circulationaha.116.027039 |
0.383 |
|
| 2017 |
Donnarumma E, Trivedi RK, Lefer DJ. Protective Actions of H2S in Acute Myocardial Infarction and Heart Failure. Comprehensive Physiology. 7: 583-602. PMID 28333381 DOI: 10.1002/Cphy.C160023 |
0.418 |
|
| 2017 |
Trivedi RK, Li Z, Polhemus DJ, Yoo D, Koiwaya H, Goodchild TT, Lefer DJ. LCZ696 Reduces Myocardial Fibrosis in Hypertensive Rats in the Setting of Heart Failure Journal of Molecular and Cellular Cardiology. 112: 162. DOI: 10.1016/J.Yjmcc.2017.07.094 |
0.354 |
|
| 2017 |
Trivedi RK, Li Z, Polhemus DJ, Yoo D, Koiwaya H, Goodchild TT, Lefer DJ. LCZ696, the First-in-Class Angiotensin Receptor Neprilysin Inhibitor, Improves Vascular Reactivity in the Setting of Heart Failure Journal of Molecular and Cellular Cardiology. 112: 162. DOI: 10.1016/J.Yjmcc.2017.07.093 |
0.337 |
|
| 2017 |
Li Z, Nguyen LO, Organ CL, Lefer DJ, Mungrue IN. Genetic inhibition of the UPR gene Chac1 preserves cardiac function in a murine model of pressure overload induced heart failure Journal of Molecular and Cellular Cardiology. 112: 160. DOI: 10.1016/J.Yjmcc.2017.07.088 |
0.352 |
|
| 2017 |
Organ C, Li Z, Zibilich C, Goodchild T, Wang S, Small KM, Madwed J, Liu J, Kozlowski J, Lefer DJ. 074A Novel Histone Deacetylase (HDAC) Inhibitor Attenuates Cardiac Dysfunction in the Setting of Pressure Overload Heart Failure Journal of Molecular and Cellular Cardiology. 112: 159. DOI: 10.1016/J.Yjmcc.2017.07.086 |
0.327 |
|
| 2017 |
Rushing A, Donnarumma E, Scarborough A, Boisvert S, Trivedi R, Polhemus D, Li Z, Au K, Victoria S, Schumacher J, Lefer D, Goodchild T. 073A Novel Hydrogen Sulfide Prodrug, SG-1002, Augments Angiogenesis and Coronary Vascular Tone in a Swine Model of Critical Limb Ischemia Journal of Molecular and Cellular Cardiology. 112: 158-159. DOI: 10.1016/J.Yjmcc.2017.07.085 |
0.321 |
|
| 2017 |
Li Z, Organ C, Polhemus D, Trivedi R, Kang J, Xian M, Lefer D. A Novel Hydrogen Sulfide Donor, JK1, Protects the Heart Against Pressure Overload Induced Heart Failure A Novel Hydrogen Sulfide Donor, JK1, Protects the Heart Against Pressure Overload Induced Heart Failure Journal of Molecular and Cellular Cardiology. 112: 158. DOI: 10.1016/J.Yjmcc.2017.07.084 |
0.367 |
|
| 2017 |
Polhemus D, Trivedi R, Goodchild T, De Couto G, Marban E, Lefer D. Cardiosphere-Derived Cells Combined with Renal Sympathetic Denervation Improves Ventricular Function and Remodeling Following Ischemic Injury Journal of Molecular and Cellular Cardiology. 112: 158. DOI: 10.1016/J.Yjmcc.2017.07.083 |
0.332 |
|
| 2017 |
Polhemus D, Trivedi R, Li Z, Koiwaya H, Goodchild T, Gao J, Kapusta D, Lefer D. Renal Sympathetic Denervation Improves Left Ventricular Function and Vascular Reactivity in Heart Failure Journal of Molecular and Cellular Cardiology. 112: 157-158. DOI: 10.1016/J.Yjmcc.2017.07.082 |
0.344 |
|
| 2017 |
Koiwaya H, Polhemus D, Trivedi R, Lefer D. Renal Sympathetic Denervation Reverses Diastolic Dysfunction in a Rodent Model of Heart Failure with Preserved Ejection Fraction (HFpEF) Journal of Molecular and Cellular Cardiology. 112: 154. DOI: 10.1016/J.Yjmcc.2017.07.071 |
0.323 |
|
| 2016 |
Donnarumma E, Bhushan S, Bradley JM, Otsuka H, Donnelly EL, Lefer DJ, Islam KN. Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure. Journal of the American Heart Association. 5. PMID 27473036 DOI: 10.1161/Jaha.116.003551 |
0.449 |
|
| 2016 |
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim-Shapiro DB, Lajous M, Larsen FJ, Lefer DJ, McClure LA, Nolan BT, Pluta R, Schechter A, Wang CY, Ward MH, et al. Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop. Journal of the American Heart Association. 5. PMID 27385425 DOI: 10.1161/Jaha.116.003402 |
0.303 |
|
| 2016 |
Donnarumma E, Ali MJ, Rushing AM, Scarborough AL, Bradley JM, Organ CL, Islam KN, Polhemus DJ, Evangelista S, Cirino G, Jenkins JS, Patel RA, Lefer DJ, Goodchild TT. Zofenopril Protects Against Myocardial Ischemia-Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability. Journal of the American Heart Association. 5. PMID 27381758 DOI: 10.1161/JAHA.116.003531 |
0.366 |
|
| 2016 |
Tejada T, Tan L, Torres RA, Calvert JW, Lambert JP, Zaidi M, Husain M, Berce MD, Naib H, Pejler G, Abrink M, Graham RM, Lefer DJ, Naqvi N, Husain A. IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274047 DOI: 10.1073/Pnas.1603127113 |
0.395 |
|
| 2016 |
Polhemus D, Gao J, Scarborough AL, Bradley JM, Trivedi RK, Smart F, Kapusta DR, Lefer DJ. RENAL DENERVATION IMPROVES POST-INFARCTION REMODELING AND HEMODYNAMICS THROUGH MODULATION OF CARDIOPROTECTIVE PLASMA PEPTIDES Journal of the American College of Cardiology. 67: 1492. DOI: 10.1016/S0735-1097(16)31493-0 |
0.346 |
|
| 2016 |
Rushing AM, Scarborough AL, Boisvert SF, Donnarumma E, Trivedi R, Polhemus DJ, Lefer DJ, Goodchild TT. A hydrogen sulfide prodrug augments angiogenesis in a swine model of critical limb ischemia via a nitric oxide dependent mechanism Artery Research. 16: 94-95. DOI: 10.1016/J.Artres.2016.08.026 |
0.364 |
|
| 2015 |
Kimura Y, Toyofuku Y, Koike S, Shibuya N, Nagahara N, Lefer D, Ogasawara Y, Kimura H. Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain. Scientific Reports. 5: 14774. PMID 26437775 DOI: 10.1038/Srep14774 |
0.308 |
|
| 2015 |
Neuman RB, Hayek SS, Poole JC, Rahman A, Menon V, Kavtaradze N, Polhemus D, Veledar E, Lefer DJ, Quyyumi AA. Nitric Oxide Contributes to Vasomotor Tone in Hypertensive African Americans Treated With Nebivolol and Metoprolol. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 26285691 DOI: 10.1111/Jch.12649 |
0.301 |
|
| 2015 |
Bradley JM, Islam KN, Polhemus DJ, Donnarumma E, Brewster LP, Tao Y, Goodchild TT, Lefer DJ. Sustained Release Nitrite Therapy Results in Myocardial Protection in a Porcine Model of Metabolic Syndrome with Peripheral Vascular Disease. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00163.2015. PMID 25957218 DOI: 10.1152/Ajpheart.00163.2015 |
0.371 |
|
| 2015 |
Jones SP, Tang XL, Guo Y, Steenbergen C, Lefer DJ, Kukreja RC, Kong M, Li Q, Bhushan S, Zhu X, Du J, Nong Y, Stowers HL, Kondo K, Hunt GN, et al. The NHLBI-sponsored Consortium for preclinicAl assESsment of cARdioprotective therapies (CAESAR): a new paradigm for rigorous, accurate, and reproducible evaluation of putative infarct-sparing interventions in mice, rabbits, and pigs. Circulation Research. 116: 572-86. PMID 25499773 DOI: 10.1161/Circresaha.116.305462 |
0.347 |
|
| 2015 |
Polhemus DJ, Elrod JW, Giordano T, Goodchild TT, Lefer DJ. Clinical evidence of hydrogen sulfide-mediated elevation in circulating nitrite Nitric Oxide. 47: S28. DOI: 10.1016/J.Niox.2015.02.067 |
0.574 |
|
| 2014 |
Polhemus DJ, Calvert JW, Butler J, Lefer DJ. The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure. Scientifica. 2014: 768607. PMID 25045576 DOI: 10.1155/2014/768607 |
0.34 |
|
| 2014 |
Naqvi N, Li M, Calvert JW, Tejada T, Lambert JP, Wu J, Kesteven SH, Holman SR, Matsuda T, Lovelock JD, Howard WW, Iismaa SE, Chan AY, Crawford BH, Wagner MB, ... ... Lefer DJ, et al. A proliferative burst during preadolescence establishes the final cardiomyocyte number. Cell. 157: 795-807. PMID 24813607 DOI: 10.1016/J.Cell.2014.03.035 |
0.394 |
|
| 2014 |
Bhushan S, Kondo K, Polhemus DJ, Otsuka H, Nicholson CK, Tao YX, Huang H, Georgiopoulou VV, Murohara T, Calvert JW, Butler J, Lefer DJ. Nitrite therapy improves left ventricular function during heart failure via restoration of nitric oxide-mediated cytoprotective signaling. Circulation Research. 114: 1281-91. PMID 24599803 DOI: 10.1161/Circresaha.114.301475 |
0.434 |
|
| 2014 |
Polhemus DJ, Lefer DJ. Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease. Circulation Research. 114: 730-7. PMID 24526678 DOI: 10.1161/Circresaha.114.300505 |
0.399 |
|
| 2014 |
King AL, Polhemus DJ, Bhushan S, Otsuka H, Kondo K, Nicholson CK, Bradley JM, Islam KN, Calvert JW, Tao YX, Dugas TR, Kelley EE, Elrod JW, Huang PL, Wang R, ... Lefer DJ, et al. Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. Proceedings of the National Academy of Sciences of the United States of America. 111: 3182-7. PMID 24516168 DOI: 10.1073/Pnas.1321871111 |
0.667 |
|
| 2014 |
Polhemus DJ, Otsuka H, Bhushan S, Islam KN, Bradley JM, Elrod JW, Lefer DJ. P83 Nitric Oxide. 39: S40-S41. DOI: 10.1016/J.Niox.2014.03.133 |
0.648 |
|
| 2014 |
Islam KN, Polhemus DJ, Otsuka H, Bhushan S, Bradley JM, Lefer DJ. P7 Activation of nuclear transcription factor-kappaB (NF-kappaB) in cystathionine gamma-lyase (CSE) knockout (KO) mice Nitric Oxide. 39: S18. DOI: 10.1016/J.Niox.2014.03.057 |
0.415 |
|
| 2014 |
Islam KN, Polhemus DJ, Otsuka H, Bhushan S, Bradley JM, Brewster LP, Lefer DJ. P6 Oxidative stress suppresses expression of cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3-MST) in critical limb ischemia (CLI) patients Nitric Oxide. 39: S17-S18. DOI: 10.1016/J.Niox.2014.03.056 |
0.325 |
|
| 2014 |
Kevil CG, Kolluru G, Pardue S, Wang R, Lefer DJ, Shen X. S7-1 Vascular sulfide metabolism during ischemia Nitric Oxide. 39: S8-S9. DOI: 10.1016/J.Niox.2014.03.031 |
0.357 |
|
| 2014 |
Gojon G, Gojon G, Lefer DJ, Elrod JW, Giordano T. S5-4 Phase I, heart failure clinical trial to evaluate the safety of SG1002 – A novel hydrogen sulfide donor Nitric Oxide. 39: S6-S7. DOI: 10.1016/J.Niox.2014.03.024 |
0.624 |
|
| 2014 |
Lefer DJ. S2-1 Hydrogen sulfide in heart failure Nitric Oxide. 39: S2. DOI: 10.1016/J.Niox.2014.03.007 |
0.455 |
|
| 2013 |
Huang ZM, Gao E, Fonseca FV, Hayashi H, Shang X, Hoffman NE, Chuprun JK, Tian X, Tilley DG, Madesh M, Lefer DJ, Stamler JS, Koch WJ. Convergence of G protein-coupled receptor and S-nitrosylation signaling determines the outcome to cardiac ischemic injury. Science Signaling. 6: ra95. PMID 24170934 DOI: 10.1126/Scisignal.2004225 |
0.418 |
|
| 2013 |
Nicholson CK, Lambert JP, Chow CW, Lefer DJ, Calvert JW. Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion. Journal of Molecular and Cellular Cardiology. 64: 1-10. PMID 23962643 DOI: 10.1016/J.Yjmcc.2013.08.002 |
0.453 |
|
| 2013 |
Calvert JW, Lefer DJ. Role of β-adrenergic receptors and nitric oxide signaling in exercise-mediated cardioprotection. Physiology (Bethesda, Md.). 28: 216-24. PMID 23817796 DOI: 10.1152/Physiol.00011.2013 |
0.36 |
|
| 2013 |
Polhemus D, Kondo K, Bhushan S, Bir SC, Kevil CG, Murohara T, Lefer DJ, Calvert JW. Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis. Circulation. Heart Failure. 6: 1077-86. PMID 23811964 DOI: 10.1161/Circheartfailure.113.000299 |
0.435 |
|
| 2013 |
Shirozu K, Tokuda K, Marutani E, Lefer D, Wang R, Ichinose F. Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure. Antioxidants & Redox Signaling. 20: 204-16. PMID 23758073 DOI: 10.1089/Ars.2013.5354 |
0.348 |
|
| 2013 |
Zhao Y, Bhushan S, Yang C, Otsuka H, Stein JD, Pacheco A, Peng B, Devarie-Baez NO, Aguilar HC, Lefer DJ, Xian M. Controllable hydrogen sulfide donors and their activity against myocardial ischemia-reperfusion injury. Acs Chemical Biology. 8: 1283-90. PMID 23547844 DOI: 10.1021/Cb400090D |
0.369 |
|
| 2013 |
Kondo K, Bhushan S, King AL, Prabhu SD, Hamid T, Koenig S, Murohara T, Predmore BL, Gojon G, Gojon G, Wang R, Karusula N, Nicholson CK, Calvert JW, Lefer DJ. Hâ‚‚S protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase. Circulation. 127: 1116-27. PMID 23393010 DOI: 10.1161/Circulationaha.112.000855 |
0.403 |
|
| 2013 |
Suk HY, Zhou C, Yang TT, Zhu H, Yu RY, Olabisi O, Yang X, Brancho D, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Lefer DJ, Molkentin JD, et al. Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. The Journal of Biological Chemistry. 288: 3477-88. PMID 23258544 DOI: 10.1074/Jbc.M112.419150 |
0.5 |
|
| 2013 |
Lefer DJ. PL07 Diallyl trisulfide (DATS) protects against heart failure via eNOS activation and nitric oxide mediated cardioprotection Nitric Oxide. 31: S14. DOI: 10.1016/J.Niox.2013.06.017 |
0.427 |
|
| 2013 |
King AL, Bushan S, Kondo K, Nicholson C, Polhemus D, Wang R, Calvert J, Lefer D. P41 Nitric Oxide. 31: S31. DOI: 10.1016/J.Niox.2013.02.043 |
0.481 |
|
| 2013 |
Bhushan S, Kondo K, Polhemus D, Ostuka H, King AL, Calvert JW, Lefer DJ. P39: Chronic sodium nitrite (NaNO2) therapy attenuates the severity of pressure overload induced heart failure in mice Nitric Oxide. 31. DOI: 10.1016/J.Niox.2013.02.041 |
0.455 |
|
| 2012 |
Bhushan S, Kondo K, Predmore BL, Zlatopolsky M, King AL, Pearce C, Huang H, Tao YX, Condit ME, Lefer DJ. Selective β2-adrenoreceptor stimulation attenuates myocardial cell death and preserves cardiac function after ischemia-reperfusion injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1865-74. PMID 22652602 DOI: 10.1161/Atvbaha.112.251769 |
0.404 |
|
| 2012 |
Kevil CG, Lefer DJ. Nitrite and nitrate: from bench to bedside. Nitric Oxide : Biology and Chemistry. 26: 195-6. PMID 22622235 DOI: 10.1016/J.Niox.2012.04.165 |
0.348 |
|
| 2012 |
Predmore BL, Kondo K, Bhushan S, Zlatopolsky MA, King AL, Aragon JP, Grinsfelder DB, Condit ME, Lefer DJ. The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability. American Journal of Physiology. Heart and Circulatory Physiology. 302: H2410-8. PMID 22467307 DOI: 10.1152/Ajpheart.00044.2012 |
0.453 |
|
| 2012 |
Calvert JW, Lefer DJ. Chapter 6 – Overview of Cardiac Muscle Physiology Musclefundamental Biology and Mechanisms of Disease. 57-66. DOI: 10.1016/B978-0-12-381510-1.00006-5 |
0.349 |
|
| 2011 |
Aragón JP, Condit ME, Bhushan S, Predmore BL, Patel SS, Grinsfelder DB, Gundewar S, Jha S, Calvert JW, Barouch LA, Lavu M, Wright HM, Lefer DJ. Beta3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation. Journal of the American College of Cardiology. 58: 2683-91. PMID 22152956 DOI: 10.1016/J.Jacc.2011.09.033 |
0.418 |
|
| 2011 |
Schwartz Longacre L, Kloner RA, Arai AE, Baines CP, Bolli R, Braunwald E, Downey J, Gibbons RJ, Gottlieb RA, Heusch G, Jennings RB, Lefer DJ, Mentzer RM, Murphy E, Ovize M, et al. New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation. 124: 1172-9. PMID 21900096 DOI: 10.1161/Circulationaha.111.032698 |
0.391 |
|
| 2011 |
Lefer DJ, Bolli R. Development of an NIH consortium for preclinicAl AssESsment of CARdioprotective therapies (CAESAR): a paradigm shift in studies of infarct size limitation. Journal of Cardiovascular Pharmacology and Therapeutics. 16: 332-9. PMID 21821536 DOI: 10.1177/1074248411414155 |
0.314 |
|
| 2011 |
King AL, Lefer DJ. Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury. Experimental Physiology. 96: 840-6. PMID 21666033 DOI: 10.1113/Expphysiol.2011.059725 |
0.361 |
|
| 2011 |
Calvert JW, Condit ME, Aragón JP, Nicholson CK, Moody BF, Hood RL, Sindler AL, Gundewar S, Seals DR, Barouch LA, Lefer DJ. Exercise protects against myocardial ischemia-reperfusion injury via stimulation of β(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols. Circulation Research. 108: 1448-58. PMID 21527738 DOI: 10.1161/Circresaha.111.241117 |
0.409 |
|
| 2011 |
Predmore BL, Lefer DJ. Hydrogen sulfide-mediated myocardial pre- and post-conditioning. Expert Review of Clinical Pharmacology. 4: 83-96. PMID 21373204 DOI: 10.1586/Ecp.10.56 |
0.342 |
|
| 2011 |
Teng R, Calvert JW, Sibmooh N, Piknova B, Suzuki N, Sun J, Martinez K, Yamamoto M, Schechter AN, Lefer DJ, Noguchi CT. Acute erythropoietin cardioprotection is mediated by endothelial response. Basic Research in Cardiology. 106: 343-54. PMID 21347618 DOI: 10.1007/S00395-011-0158-Z |
0.407 |
|
| 2011 |
Sindler AL, Fleenor BS, Calvert JW, Marshall KD, Zigler ML, Lefer DJ, Seals DR. Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging. Aging Cell. 10: 429-37. PMID 21276184 DOI: 10.1111/J.1474-9726.2011.00679.X |
0.339 |
|
| 2011 |
Lavu M, Bhushan S, Lefer DJ. Hydrogen sulfide-mediated cardioprotection: mechanisms and therapeutic potential. Clinical Science (London, England : 1979). 120: 219-29. PMID 21126235 DOI: 10.1042/Cs20100462 |
0.363 |
|
| 2011 |
Lavu M, Gundewar S, Lefer DJ. Gene therapy for ischemic heart disease. Journal of Molecular and Cellular Cardiology. 50: 742-50. PMID 20600100 DOI: 10.1016/J.Yjmcc.2010.06.007 |
0.346 |
|
| 2011 |
Kondo K, Bhushan S, Lefer D. P64. Administration of oral nitrite and cardiac dysfunction following pressure overload induced hypertrophy – A preliminary study Nitric Oxide. 24. DOI: 10.1016/J.Niox.2011.03.295 |
0.324 |
|
| 2011 |
Bhushan S, Elston M, Aragon JP, Lavu M, Calvert JW, Predmore B, Kondo K, Lefer D. P62. Sodium nitrite therapy fails to attenuate the severity of ischemia-induced heart failure Nitric Oxide. 24: S38. DOI: 10.1016/J.Niox.2011.03.293 |
0.373 |
|
| 2011 |
Elston M, Aragon JP, Barouch L, Calvert J, Lefer D. P20. Stimulation of β3-adrenergic receptors during exercise protects the heart against ischemia-reperfusion injury by increasing the cardiac storage of nitrite and nitrosothiols Nitric Oxide. 24: S23. DOI: 10.1016/J.Niox.2011.03.251 |
0.382 |
|
| 2011 |
Predmore B, Aragon JP, Patel S, Grinsfelder B, Gundewar S, Jha S, Elston M, Calvert J, Barouch L, Lavu M, Wright H, Bhushan S, Lefer D. P19. Stimulation of the beta 3-adrenergic receptor protects against myocardial ischemia-reperfusion injury by increasing cardiac nitrite levels Nitric Oxide. 24: S23. DOI: 10.1016/J.Niox.2011.03.250 |
0.378 |
|
| 2011 |
King AL, Bushan S, Predmore B, Condit M, Aragon JP, Wang R, Lefer D. Cystathionine Gamma-lyase (CSE) Deficiency Increases Oxidative Stress and Exacerbates Cardiac Mitochondrial Dysfunction and Myocardial Reperfusion Injury Free Radical Biology and Medicine. 51: S43. DOI: 10.1016/J.Freeradbiomed.2011.10.106 |
0.397 |
|
| 2011 |
Bhushan S, Lavu M, Predmore B, Elston M, Aragon JP, Jha S, Gundewar S, Lefer D. Genetic deficiency of cystathionine gamma-lyase exacerbates myocardial reperfusion injury and is rescued by exogenous hydrogen sulfide Cardiovascular Revascularization Medicine. 12: 193. DOI: 10.1016/J.Carrev.2011.02.011 |
0.384 |
|
| 2010 |
Muzumdar RH, Huffman DM, Calvert JW, Jha S, Weinberg Y, Cui L, Nemkal A, Atzmon G, Klein L, Gundewar S, Ji SY, Lavu M, Predmore BL, Lefer DJ. Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1940-8. PMID 20651283 DOI: 10.1161/Atvbaha.110.205997 |
0.418 |
|
| 2010 |
Predmore BL, Lefer DJ. Development of hydrogen sulfide-based therapeutics for cardiovascular disease. Journal of Cardiovascular Translational Research. 3: 487-98. PMID 20628909 DOI: 10.1007/S12265-010-9201-Y |
0.317 |
|
| 2010 |
Calvert JW, Elston M, Nicholson CK, Gundewar S, Jha S, Elrod JW, Ramachandran A, Lefer DJ. Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. Circulation. 122: 11-9. PMID 20566952 DOI: 10.1161/Circulationaha.109.920991 |
0.655 |
|
| 2010 |
Lefer DJ. Is there a better time of day to have a heart attack? Circulation Research. 106: 430-1. PMID 20167939 DOI: 10.1161/Circresaha.109.213652 |
0.329 |
|
| 2010 |
Calvert JW, Lefer DJ. Clinical translation of nitrite therapy for cardiovascular diseases. Nitric Oxide : Biology and Chemistry. 22: 91-7. PMID 19909823 DOI: 10.1016/J.Niox.2009.11.001 |
0.365 |
|
| 2010 |
Calvert JW, Coetzee WA, Lefer DJ. Novel insights into hydrogen sulfide--mediated cytoprotection. Antioxidants & Redox Signaling. 12: 1203-17. PMID 19769484 DOI: 10.1089/Ars.2009.2882 |
0.374 |
|
| 2010 |
Aragon JP, Patel S, Elston M, Calvert JW, Grinsfelder DB, Lefer DJ. THE β1 BLOCKER/β3 AGONIST NEBIVOLOL PROTECTS AGAINST ACUTE MYOCARDIAL INFARCTION IN MICE Journal of the American College of Cardiology. 55: A116.E1090. DOI: 10.1016/S0735-1097(10)61091-1 |
0.315 |
|
| 2010 |
Predmore BL, Grinsfelder DB, Aragon JP, Elston M, Calvert JW, Lefer DJ. THE STABLE HYDROGEN SULFIDE DONOR, DIALLYL TRISULFIDE, PROTECTS AGAINST ACUTE MYOCARDIAL INFARCTION IN MICE Journal of the American College of Cardiology. 55: A116.E1089. DOI: 10.1016/S0735-1097(10)61090-X |
0.395 |
|
| 2010 |
Calvert JW, Gundewar S, Elrod J, Lefer DJ. HYDROGEN SULFIDE CONFERS CARDIOPROTECTION IN THE SETTING OF DIABETES Journal of the American College of Cardiology. 55: A116.E1082. DOI: 10.1016/S0735-1097(10)61083-2 |
0.558 |
|
| 2010 |
Calvert JW, Elston M, Jha S, Gundewar S, Aragon JP, Grinsfelder DB, Ramachandran A, Elrod JW, Lefer DJ. HYDROGEN SULFIDE THERAPY ATTENUATES ISCHEMIA-INDUCED HEART FAILURE VIA NRF2 AND NRF1 SIGNALING Journal of the American College of Cardiology. 55: A20.E186. DOI: 10.1016/S0735-1097(10)60187-8 |
0.643 |
|
| 2009 |
Lefer DJ. Emerging role of nitrite in myocardial protection. Archives of Pharmacal Research. 32: 1127-38. PMID 19727605 DOI: 10.1007/S12272-009-1804-Y |
0.419 |
|
| 2009 |
Minamishima S, Bougaki M, Sips PY, Yu JD, Minamishima YA, Elrod JW, Lefer DJ, Bloch KD, Ichinose F. Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. Circulation. 120: 888-96. PMID 19704099 DOI: 10.1161/Circulationaha.108.833491 |
0.615 |
|
| 2009 |
Calvert JW, Jha S, Gundewar S, Elrod JW, Ramachandran A, Pattillo CB, Kevil CG, Lefer DJ. Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circulation Research. 105: 365-74. PMID 19608979 DOI: 10.1161/Circresaha.109.199919 |
0.555 |
|
| 2009 |
Lefer DJ, Nichols CG, Coetzee WA. Sulfonylurea receptor 1 subunits of ATP-sensitive potassium channels and myocardial ischemia/reperfusion injury. Trends in Cardiovascular Medicine. 19: 61-7. PMID 19577714 DOI: 10.1016/J.Tcm.2009.04.008 |
0.348 |
|
| 2009 |
Granfeldt A, Lefer DJ, Vinten-Johansen J. Protective ischaemia in patients: preconditioning and postconditioning. Cardiovascular Research. 83: 234-46. PMID 19398470 DOI: 10.1093/Cvr/Cvp129 |
0.393 |
|
| 2009 |
Calvert JW, Lefer DJ, Gundewar S, Poston L, Coetzee WA. Developmental programming resulting from maternal obesity in mice: effects on myocardial ischaemia-reperfusion injury. Experimental Physiology. 94: 805-14. PMID 19395658 DOI: 10.1113/Expphysiol.2009.047183 |
0.303 |
|
| 2009 |
Calvert JW, Lefer DJ. Myocardial protection by nitrite. Cardiovascular Research. 83: 195-203. PMID 19251721 DOI: 10.1093/Cvr/Cvp079 |
0.414 |
|
| 2009 |
Gundewar S, Calvert JW, Jha S, Toedt-Pingel I, Ji SY, Nunez D, Ramachandran A, Anaya-Cisneros M, Tian R, Lefer DJ. Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure. Circulation Research. 104: 403-11. PMID 19096023 DOI: 10.1161/CIRCRESAHA.108.190918 |
0.314 |
|
| 2008 |
Elrod JW, Calvert JW, Gundewar S, Bryan NS, Lefer DJ. Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 105: 11430-5. PMID 18685092 DOI: 10.1073/Pnas.0800700105 |
0.638 |
|
| 2008 |
Jha S, Calvert JW, Duranski MR, Ramachandran A, Lefer DJ. Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling. American Journal of Physiology. Heart and Circulatory Physiology. 295: H801-6. PMID 18567706 DOI: 10.1152/Ajpheart.00377.2008 |
0.385 |
|
| 2008 |
Bryan NS, Calvert JW, Gundewar S, Lefer DJ. Dietary nitrite restores NO homeostasis and is cardioprotective in endothelial nitric oxide synthase-deficient mice. Free Radical Biology & Medicine. 45: 468-74. PMID 18501719 DOI: 10.1016/j.freeradbiomed.2008.04.040 |
0.307 |
|
| 2008 |
Elrod JW, Harrell M, Flagg TP, Gundewar S, Magnuson MA, Nichols CG, Coetzee WA, Lefer DJ. Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation. 117: 1405-13. PMID 18316485 DOI: 10.1161/Circulationaha.107.745539 |
0.614 |
|
| 2008 |
Gundewar S, Lefer DJ. Sphingolipid therapy in myocardial ischemia-reperfusion injury. Biochimica Et Biophysica Acta. 1780: 571-6. PMID 17928150 DOI: 10.1016/j.bbagen.2007.08.014 |
0.344 |
|
| 2007 |
Bryan NS, Calvert JW, Elrod JW, Gundewar S, Ji SY, Lefer DJ. Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America. 104: 19144-9. PMID 18025468 DOI: 10.1073/Pnas.0706579104 |
0.647 |
|
| 2007 |
Calvert JW, Gundewar S, Yamakuchi M, Park PC, Baldwin WM, Lefer DJ, Lowenstein CJ. Inhibition of N-ethylmaleimide-sensitive factor protects against myocardial ischemia/reperfusion injury. Circulation Research. 101: 1247-54. PMID 17932325 DOI: 10.1161/Circresaha.107.162610 |
0.321 |
|
| 2007 |
Elrod JW, Calvert JW, Morrison J, Doeller JE, Kraus DW, Tao L, Jiao X, Scalia R, Kiss L, Szabo C, Kimura H, Chow CW, Lefer DJ. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 104: 15560-5. PMID 17878306 DOI: 10.1073/Pnas.0705891104 |
0.634 |
|
| 2007 |
Gundewar S, Calvert JW, Elrod JW, Lefer DJ. Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2462-71. PMID 17630348 DOI: 10.1152/Ajpheart.00392.2007 |
0.659 |
|
| 2007 |
Senthilkumar A, Smith RD, Khitha J, Arora N, Veerareddy S, Langston W, Chidlow JH, Barlow SC, Teng X, Patel RP, Lefer DJ, Kevil CG. Sildenafil promotes ischemia-induced angiogenesis through a PKG-dependent pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1947-54. PMID 17585066 DOI: 10.1161/Atvbaha.107.147421 |
0.349 |
|
| 2007 |
Elrod JW, Greer JJ, Lefer DJ. Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway. American Journal of Physiology. Heart and Circulatory Physiology. 292: H342-7. PMID 16951048 DOI: 10.1152/Ajpheart.00306.2006 |
0.669 |
|
| 2006 |
Duranski MR, Elrod JW, Calvert JW, Bryan NS, Feelisch M, Lefer DJ. Genetic overexpression of eNOS attenuates hepatic ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2980-6. PMID 16877550 DOI: 10.1152/Ajpheart.01173.2005 |
0.648 |
|
| 2006 |
Greer JJ, Kakkar AK, Elrod JW, Watson LJ, Jones SP, Lefer DJ. Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2743-51. PMID 16844920 DOI: 10.1152/Ajpheart.00347.2006 |
0.644 |
|
| 2006 |
Elrod JW, Duranski MR, Langston W, Greer JJ, Tao L, Dugas TR, Kevil CG, Champion HC, Lefer DJ. eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling. Circulation Research. 99: 78-85. PMID 16763164 DOI: 10.1161/01.Res.0000231306.03510.77 |
0.622 |
|
| 2006 |
Elrod JW, Greer JJ, Bryan NS, Langston W, Szot JF, Gebregzlabher H, Janssens S, Feelisch M, Lefer DJ. Cardiomyocyte-specific overexpression of NO synthase-3 protects against myocardial ischemia-reperfusion injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1517-23. PMID 16645153 DOI: 10.1161/01.Atv.0000224324.52466.E6 |
0.638 |
|
| 2006 |
Greer JJ, Ware DP, Lefer DJ. Myocardial infarction and heart failure in the db/db diabetic mouse. American Journal of Physiology. Heart and Circulatory Physiology. 290: H146-53. PMID 16113078 DOI: 10.1152/ajpheart.00583.2005 |
0.33 |
|
| 2005 |
Mori M, Stokes KY, Vowinkel T, Watanabe N, Elrod JW, Harris NR, Lefer DJ, Hibi T, Granger DN. Colonic blood flow responses in experimental colitis: time course and underlying mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G1024-9. PMID 16081759 DOI: 10.1152/Ajpgi.00247.2005 |
0.59 |
|
| 2005 |
Elrod JW, Lefer DJ. The effects of statins on endothelium, inflammation and cardioprotection. Drug News & Perspectives. 18: 229-36. PMID 16034478 DOI: 10.1358/Dnp.2005.18.4.908656 |
0.618 |
|
| 2005 |
Wright DG, Lefer DJ. Statin mediated protection of the ischemic myocardium. Vascular Pharmacology. 42: 265-70. PMID 15922259 DOI: 10.1016/J.Vph.2005.02.006 |
0.447 |
|
| 2005 |
Yamakuchi M, Greer JJ, Cameron SJ, Matsushita K, Morrell CN, Talbot-Fox K, Baldwin WM, Lefer DJ, Lowenstein CJ. HMG-CoA reductase inhibitors inhibit endothelial exocytosis and decrease myocardial infarct size. Circulation Research. 96: 1185-92. PMID 15905463 DOI: 10.1161/01.Res.0000170229.49776.81 |
0.305 |
|
| 2005 |
Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang X, Kevil CG, Gladwin MT, Lefer DJ. Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. The Journal of Clinical Investigation. 115: 1232-40. PMID 15841216 DOI: 10.1172/Jci22493 |
0.342 |
|
| 2005 |
Jones SP, Greer JJ, Ware PD, Yang J, Walsh K, Lefer DJ. Deficiency of iNOS does not attenuate severe congestive heart failure in mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H365-70. PMID 15319210 DOI: 10.1152/Ajpheart.00245.2004 |
0.412 |
|
| 2005 |
Shiva S, Huang Z, Ringwood LA, Lefer DJ, Gladwin MT. Reduction of Nitrite to Nitric Oxide by Myoglobin Modulates Mitochondrial Respiration during Ischemia and Limits Reperfusion Injury. Blood. 106: 1673-1673. DOI: 10.1182/Blood.V106.11.1673.1673 |
0.353 |
|
| 2004 |
Walsh EK, Huang H, Wang Z, Williams J, De Crom R, Van Haperen R, Thompson CI, Lefer DJ, Hintze TH. Control of myocardial oxygen consumption in transgenic mice overexpressing vascular eNOS American Journal of Physiology - Heart and Circulatory Physiology. 287. PMID 15284070 DOI: 10.1152/Ajpheart.00267.2004 |
0.312 |
|
| 2004 |
Kakkar AK, Lefer DJ. Leukocyte and endothelial adhesion molecule studies in knockout mice. Current Opinion in Pharmacology. 4: 154-8. PMID 15063359 DOI: 10.1016/j.coph.2004.01.003 |
0.303 |
|
| 2004 |
Jones SP, Greer JJ, Kakkar AK, Ware PD, Turnage RH, Hicks M, van Haperen R, de Crom R, Kawashima S, Yokoyama M, Lefer DJ. Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 286: H276-82. PMID 12969888 DOI: 10.1152/Ajpheart.00129.2003 |
0.415 |
|
| 2004 |
Jaganmohan S, Duranski M, Dejam A, Gladwin MT, Kevil CG, Langston W, Lefer DJ. Cytoprotective Effects Of Nitrite During Ischemia-Reperfusion Of The Liver: 254 The American Journal of Gastroenterology. 99. DOI: 10.14309/00000434-200410001-00253 |
0.311 |
|
| 2003 |
Sasaki M, Bharwani S, Jordan P, Elrod JW, Grisham MB, Jackson TH, Lefer DJ, Alexander JS. Increased disease activity in eNOS-deficient mice in experimental colitis. Free Radical Biology & Medicine. 35: 1679-87. PMID 14680690 DOI: 10.1016/J.Freeradbiomed.2003.09.016 |
0.592 |
|
| 2003 |
Jones SP, Greer JJ, van Haperen R, Duncker DJ, de Crom R, Lefer DJ. Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 4891-6. PMID 12676984 DOI: 10.1073/Pnas.0837428100 |
0.448 |
|
| 2003 |
Yang J, Jones SP, Suhara T, Greer JJ, Ware PD, Nguyen NP, Perlman H, Nelson DP, Lefer DJ, Walsh K. Endothelial cell overexpression of fas ligand attenuates ischemia-reperfusion injury in the heart. The Journal of Biological Chemistry. 278: 15185-91. PMID 12576484 DOI: 10.1074/Jbc.M211707200 |
0.371 |
|
| 2003 |
Harada H, Pavlick KP, Hines IN, Lefer DJ, Hoffman JM, Bharwani S, Wolf RE, Grisham MB. Sexual dimorphism in reduced-size liver ischemia and reperfusion injury in mice: role of endothelial cell nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 100: 739-44. PMID 12522262 DOI: 10.1073/Pnas.0235680100 |
0.373 |
|
| 2003 |
Jones SP, Hoffmeyer MR, Sharp BR, Ho YS, Lefer DJ. Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 284: H277-82. PMID 12485820 DOI: 10.1152/AJPHEART.00236.2002 |
0.336 |
|
| 2003 |
Lee P, Sata M, Lefer DJ, Factor SM, Walsh K, Kitsis RN. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 284: H456-63. PMID 12414449 DOI: 10.1152/Ajpheart.00777.2002 |
0.301 |
|
| 2002 |
Sharp BR, Jones SP, Rimmer DM, Lefer DJ. Differential response to myocardial reperfusion injury in eNOS-deficient mice. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2422-6. PMID 12003854 DOI: 10.1152/Ajpheart.00855.2001 |
0.42 |
|
| 2002 |
Jones SP, Trocha SD, Lefer DJ. Pretreatment with simvastatin attenuates myocardial dysfunction after ischemia and chronic reperfusion. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 2059-64. PMID 11742885 DOI: 10.1161/Hq1201.099509 |
0.446 |
|
| 2001 |
Chang WL, Jones SP, Lefer DJ, Welbourne T, Sun G, Yin L, Suzuki H, Huang J, Granger DN, van der Heyde HC. CD8(+)-T-cell depletion ameliorates circulatory shock in Plasmodium berghei-infected mice. Infection and Immunity. 69: 7341-8. PMID 11705906 DOI: 10.1128/Iai.69.12.7341-7348.2001 |
0.302 |
|
| 2001 |
Condorelli G, Roncarati R, Ross J, Pisani A, Stassi G, Todaro M, Trocha S, Drusco A, Gu Y, Russo MA, Frati G, Jones SP, Lefer DJ, Napoli C, Croce CM. Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 98: 9977-82. PMID 11493678 DOI: 10.1073/Pnas.161120198 |
0.325 |
|
| 2001 |
Lefer DJ, Scalia R, Jones SP, Sharp BR, Hoffmeyer MR, Farvid AR, Gibson MF, Lefer AM. HMG-CoA reductase inhibition protects the diabetic myocardium from ischemia-reperfusion injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1454-6. PMID 11387255 DOI: 10.1096/Fj.00-0819Fje |
0.388 |
|
| 2001 |
Scalia R, Gooszen ME, Jones SP, Hoffmeyer M, Rimmer DM, Trocha SD, Huang PL, Smith MB, Lefer AM, Lefer DJ. Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice. Circulation. 103: 2598-603. PMID 11382730 DOI: 10.1161/01.Cir.103.21.2598 |
0.407 |
|
| 2001 |
Jones SP, Girod WG, Marotti KR, Aw TY, Lefer DJ. Acute exposure to a high cholesterol diet attenuates myocardial ischemia-reperfusion injury in cholesteryl ester transfer protein mice. Coronary Artery Disease. 12: 37-44. PMID 11211164 DOI: 10.1097/00019501-200102000-00006 |
0.406 |
|
| 2001 |
Jones SP, Lefer DJ. Simvastatin attenuates contractile dysfunction following ischemia and chronic reperfusion Journal of Molecular and Cellular Cardiology. 33. DOI: 10.1016/S0022-2828(01)90216-0 |
0.369 |
|
| 2000 |
Laroux FS, Lefer DJ, Kawachi S, Scalia R, Cockrell AS, Gray L, Van der Heyde H, Hoffman JM, Grisham MB. Role of nitric oxide in the regulation of acute and chronic inflammation Antioxidants and Redox Signaling. 2: 391-396. PMID 11229352 DOI: 10.1089/15230860050192161 |
0.315 |
|
| 2000 |
Jones SP, Lefer DJ. Using gene-targeted mice to investigate the pathophysiology of myocardial reperfusion injury. Basic Research in Cardiology. 95: 499-502. PMID 11192372 DOI: 10.1007/S003950070027 |
0.392 |
|
| 2000 |
Jones SP, Girod WG, Huang PL, Lefer DJ. Myocardial reperfusion injury in neuronal nitric oxide synthase deficient mice Coronary Artery Disease. 11: 593-597. PMID 11107506 DOI: 10.1097/00019501-200012000-00004 |
0.466 |
|
| 2000 |
Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF, Kitsis RN, Molkentin JD. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. The Embo Journal. 19: 6341-50. PMID 11101507 DOI: 10.1093/Emboj/19.23.6341 |
0.47 |
|
| 2000 |
Hoffmeyer MR, Scalia R, Ross CR, Jones SP, Lefer DJ. PR-39, a potent neutrophil inhibitor, attenuates myocardial ischemia-reperfusion injury in mice American Journal of Physiology - Heart and Circulatory Physiology. 279: H2824-H2828. PMID 11087237 DOI: 10.1152/Ajpheart.2000.279.6.H2824 |
0.316 |
|
| 2000 |
Hoffmeyer MR, Jones SP, Ross CR, Sharp B, Grisham MB, Laroux FS, Stalker TJ, Scalia R, Lefer DJ. Myocardial ischemia/reperfusion injury in NADPH oxidase-deficient mice. Circulation Research. 87: 812-7. PMID 11055986 DOI: 10.1161/01.Res.87.9.812 |
0.436 |
|
| 1999 |
Girod WG, Jones SP, Sieber N, Aw TY, Lefer DJ. Effects of Hypercholesterolemia on Myocardial Ischemia-Reperfusion Injury in LDL Receptor–Deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2776-2781. PMID 10559025 DOI: 10.1161/01.Atv.19.11.2776 |
0.386 |
|
| 1999 |
Scalia R, Booth G, Lefer DJ. Vascular endothelial growth factor attenuates leukocyte-endothelium interaction during acute endothelial dysfunction: essential role of endothelium-derived nitric oxide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1039-46. PMID 10336886 DOI: 10.1096/Fasebj.13.9.1039 |
0.317 |
|
| 1999 |
Jones SP, Girod WG, Palazzo AJ, Granger DN, Grisham MB, Jourd'heuil D, Huang PL, Lefer DJ. Myocardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase American Journal of Physiology - Heart and Circulatory Physiology. 276. PMID 10330240 DOI: 10.1152/Ajpheart.1999.276.5.H1567 |
0.315 |
|
| 1999 |
Lefer AM, Lefer DJ. Nitric oxide. II. Nitric oxide protects in intestinal inflammation. The American Journal of Physiology. 276: G572-5. PMID 10070031 DOI: 10.1152/Ajpgi.1999.276.3.G572 |
0.362 |
|
| 1997 |
Lefer DJ, Scalia R, Campbell B, Nossuli T, Hayward R, Salamon M, Grayson J, Lefer AM. Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. The Journal of Clinical Investigation. 99: 684-91. PMID 9045871 DOI: 10.1172/Jci119212 |
0.302 |
|
| 1994 |
Albertine KH, Weyrich AS, Ma XL, Lefer DJ, Becker LC, Lefer AM. Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs Journal of Leukocyte Biology. 55: 557-566. PMID 8182334 DOI: 10.1002/Jlb.55.5.557 |
0.32 |
|
| 1993 |
Ma XL, Weyrich AS, Lefer DJ, Buerke M, Albertine KH, Kishimoto TK, Lefer AM. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium Circulation. 88: 649-658. PMID 7687936 DOI: 10.1161/01.Cir.88.2.649 |
0.305 |
|
| 1992 |
Vinten-johansen J, Lefer DJ, Nakanishi K, Johnston WE, Brian CA, Cordell AR. Controlled coronary hydrodynamics at the time of reperfusion reduces postischemic injury Coronary Artery Disease. 3: 1081-1094. DOI: 10.1097/00019501-199211000-00012 |
0.336 |
|
| 1991 |
Lefer AM, Tsao PS, Lefer DJ, Ma XL. Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2029-34. PMID 2010056 DOI: 10.1096/fasebj.5.7.2010056 |
0.335 |
|
| 1991 |
Lefer AM, Lefer DJ. Endothelial dysfunction in myocardial ischemia and reperfusion: role of oxygen-derived free radicals. Basic Research in Cardiology. 109-16. PMID 1659371 DOI: 10.1007/978-3-642-72461-9_12 |
0.352 |
|
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