Year |
Citation |
Score |
2023 |
Bullert A, Li X, Zhang C, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure. Biorxiv : the Preprint Server For Biology. PMID 37609242 DOI: 10.1101/2023.06.19.544952 |
0.499 |
|
2023 |
Bullert A, Li X, Chunyun Z, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure. Environmental Toxicology and Pharmacology. 104245. PMID 37572994 DOI: 10.1016/j.etap.2023.104245 |
0.499 |
|
2022 |
Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Lehmler HJ, Ankrum JA, Klingelhutz AJ. Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3',4,4',5-Pentachlorobiphenyl (PCB126). Data in Brief. 45: 108571. PMID 36131953 DOI: 10.1016/j.dib.2022.108571 |
0.472 |
|
2021 |
Duffel MW, Tuttle K, Lehmler HJ, Robertson LW. Human hepatic microsomal sulfatase catalyzes the hydrolysis of polychlorinated biphenyl sulfates: A potential mechanism for retention of hydroxylated PCBs. Environmental Toxicology and Pharmacology. 88: 103757. PMID 34688910 DOI: 10.1016/j.etap.2021.103757 |
0.531 |
|
2020 |
Wang H, Adamcakova-Dodd A, Flor S, Gosse L, Klenov VE, Stolwijk JM, Lehmler HJ, Hornbuckle KC, Ludewig G, Robertson LW, Thorne PS. Comprehensive Subchronic Inhalation Toxicity Assessment of an Indoor School Air Mixture of PCBs. Environmental Science & Technology. PMID 33256405 DOI: 10.1021/acs.est.0c04470 |
0.479 |
|
2020 |
Zhang CY, Flor S, Ruiz P, Dhakal R, Hu X, Teesch LM, Ludewig G, Lehmler HJ. 3,3'-Dichlorobiphenyl is Metabolized to a Complex Mixture of Oxidative Metabolites, Including Novel Methoxylated Metabolites, by HepG2 Cells. Environmental Science & Technology. PMID 32910851 DOI: 10.1021/Acs.Est.0C03476 |
0.789 |
|
2020 |
Simonsen D, Cwiertny DM, Lehmler HJ. Benoxacor is enantioselectively metabolized by rat liver subcellular fractions. Chemico-Biological Interactions. 109247. PMID 32866466 DOI: 10.1016/J.Cbi.2020.109247 |
0.319 |
|
2020 |
Li X, Zhang C, Wang K, Lehmler HJ. Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase. Environmental Pollution (Barking, Essex : 1987). 266: 115233. PMID 32712482 DOI: 10.1016/J.Envpol.2020.115233 |
0.314 |
|
2020 |
Grimm FA, Klaren WD, Li X, Lehmler HJ, Karmakar M, Robertson LW, Chiu WA, Rusyn I. Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites. Environmental Health Perspectives. 128: 77008. PMID 32701041 DOI: 10.1289/Ehp7030 |
0.502 |
|
2020 |
Lim JJ, Li X, Lehmler HJ, Wang D, Gu H, Cui JY. Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32544245 DOI: 10.1093/Toxsci/Kfaa090 |
0.354 |
|
2020 |
Egusquiza RJ, Ambrosio ME, Wang SG, Kay KM, Zhang C, Lehmler HJ, Blumberg B. Evaluating the Role of the Steroid and Xenobiotic Receptor (SXR/PXR) in PCB-153 Metabolism and Protection against Associated Adverse Effects during Perinatal and Chronic Exposure in Mice. Environmental Health Perspectives. 128: 47011. PMID 32352317 DOI: 10.1289/Ehp6262 |
0.312 |
|
2020 |
Thompson DA, Lehmler HJ, Kolpin DW, Hladik ML, Vargo JD, Schilling KE, LeFevre GH, Peeples TL, Poch MC, LaDuca LE, Cwiertny DM, Field RW. A critical review on the potential impacts of neonicotinoid insecticide use: current knowledge of environmental fate, toxicity, and implications for human health. Environmental Science. Processes & Impacts. PMID 32267911 DOI: 10.1039/C9Em00586B |
0.311 |
|
2020 |
Elser BA, Kayali K, Dhakal R, O'Hare B, Wang K, Lehmler HJ, Stevens HE. Combined maternal exposure to cypermethrin and stress affect embryonic brain and placental outcomes in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32191333 DOI: 10.1093/Toxsci/Kfaa040 |
0.758 |
|
2019 |
Dhakal R, Parkin S, Lehmler HJ. 3-(3,5-Dichlorophenyl)benzene-1,2-diol. Iucrdata. 4. PMID 34708161 DOI: 10.1107/s2414314619012021 |
0.775 |
|
2019 |
Dhakal R, Parkin S, Lehmler HJ. 2,3-Dichloro-3',4'-dihydroxybiphenyl. Iucrdata. 4. PMID 32030359 DOI: 10.1107/S241431461900662X |
0.784 |
|
2019 |
Dhakal R, Parkin S, Lehmler HJ. 3,5-Dichloro-3',4'-dimethoxybiphenyl. Iucrdata. 4. PMID 32030358 DOI: 10.1107/S2414314619005182 |
0.779 |
|
2019 |
Dhakal R, Li X, Parkin SR, Lehmler HJ. Synthesis of mono- and dimethoxylated polychlorinated biphenyl derivatives starting from fluoroarene derivatives. Environmental Science and Pollution Research International. PMID 31893358 DOI: 10.1007/S11356-019-07133-3 |
0.792 |
|
2019 |
Wu X, Zhai G, Schnoor JL, Lehmler HJ. Atropselective Disposition of 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) and Identification of Its Metabolites in Mice with Liver-specific Deletion of Cytochrome P450 Reductase. Chemical Research in Toxicology. PMID 31403789 DOI: 10.1021/Acs.Chemrestox.9B00255 |
0.327 |
|
2019 |
Saktrakulkla P, Dhakal RC, Lehmler HJ, Hornbuckle KC. A semi-target analytical method for quantification of OH-PCBs in environmental samples. Environmental Science and Pollution Research International. PMID 31359319 DOI: 10.1007/S11356-019-05775-X |
0.777 |
|
2019 |
Uwimana E, Cagle B, Yeung C, Li X, Patterson EV, Doorn JA, Lehmler HJ. Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31268529 DOI: 10.1093/Toxsci/Kfz150 |
0.389 |
|
2019 |
Gadogbe M, Bao W, Wels BR, Dai SY, Santillan DA, Santillan MK, Lehmler HJ. Levels of tin and organotin compounds in human urine samples from Iowa, United States. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 1-7. PMID 31057082 DOI: 10.1080/10934529.2019.1605779 |
0.319 |
|
2019 |
Lehmler HJ, Rama Rao VV, Nauduri D, Vargo JD, Parkin S. Synthesis and Structure of Environmentally Relevant Perfluorinated Sulfonamides. Journal of Fluorine Chemistry. 128: 595-607. PMID 18516235 DOI: 10.1016/J.Jfluchem.2007.01.013 |
0.303 |
|
2019 |
Dhakal R, Parkin S, Lehmler H. 3-(3,5-Dichlorophenyl)benzene-1,2-diol Iucrdata. 4. DOI: 10.1107/S2414314619012021 |
0.781 |
|
2018 |
Liu Y, Richardson ES, Derocher AE, Lunn NJ, Lehmler HJ, Li X, Zhang Y, Cui JY, Cheng L, Martin JW. Hundreds of Unrecognized Halogenated Contaminants Discovered in Polar Bear Serum. Angewandte Chemie (International Ed. in English). PMID 30376612 DOI: 10.1002/Anie.201809906 |
0.33 |
|
2018 |
Alam S, Carter GS, Krager KJ, Li X, Lehmler HJ, Aykin-Burns N. PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD. Antioxidants (Basel, Switzerland). 7. PMID 30223548 DOI: 10.3390/Antiox7090121 |
0.337 |
|
2018 |
Rodriguez EA, Vanle BC, Doorn JA, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environmental Toxicology and Pharmacology. 62: 69-78. PMID 29986280 DOI: 10.1016/J.Etap.2018.06.010 |
0.556 |
|
2018 |
Uwimana E, Li X, Lehmler HJ. Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite. Environmental Science & Technology. 52: 6000-6008. PMID 29659268 DOI: 10.1021/Acs.Est.8B00612 |
0.375 |
|
2018 |
Pěnčíková K, Svržková L, Strapáčová S, Neča J, Bartoňková I, Dvořák Z, Hýžďalová M, Pivnička J, Pálková L, Lehmler HJ, Li X, Vondráček J, Machala M. In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion. Environmental Pollution (Barking, Essex : 1987). 237: 473-486. PMID 29518658 DOI: 10.1016/J.Envpol.2018.02.067 |
0.365 |
|
2018 |
Parker VS, Squirewell EJ, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1. Environmental Toxicology and Pharmacology. 58: 196-201. PMID 29408762 DOI: 10.1016/J.Etap.2018.01.010 |
0.569 |
|
2018 |
Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environmental Science and Pollution Research International. PMID 29322390 DOI: 10.1007/S11356-017-1162-0 |
0.478 |
|
2017 |
Schroer HW, Li X, Lehmler HJ, Just CL. Metabolism and Photolysis of 2,4-Dinitroanisole in Arabidopsis. Environmental Science & Technology. PMID 29131608 DOI: 10.1021/Acs.Est.7B04220 |
0.305 |
|
2017 |
Kania-Korwel I, Wu X, Wang K, Lehmler HJ. Identification of Lipidomic Markers of Chronic 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Exposure in the Male Rat Liver. Toxicology. PMID 28890136 DOI: 10.1016/J.Tox.2017.09.005 |
0.327 |
|
2017 |
Dhakal K, Gadupudi GS, Lehmler HJ, Ludewig G, Duffel MW, Robertson LW. Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environmental Science and Pollution Research International. PMID 28744683 DOI: 10.1007/S11356-017-9694-X |
0.797 |
|
2016 |
Uwimana E, Maiers AM, Li X, Lehmler HJ. Microsomal metabolism of prochiral polychlorinated biphenyls results in the enantioselective formation of chiral metabolites. Environmental Science & Technology. PMID 28038482 DOI: 10.1021/Acs.Est.6B05387 |
0.41 |
|
2016 |
Uwimana E, Li X, Lehmler HJ. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes. Chemical Research in Toxicology. 29: 2108-2110. PMID 27989147 DOI: 10.1021/Acs.Chemrestox.6B00371 |
0.37 |
|
2016 |
Schroer HW, Langenfeld KL, Li X, Lehmler HJ, Just CL. Biotransformation of 2,4-dinitroanisole by a fungal Penicillium sp. Biodegradation. PMID 27913891 DOI: 10.1007/S10532-016-9780-7 |
0.319 |
|
2016 |
Grimm FA, Lehmler HJ, Koh WX, DeWall J, Teesch LM, Hornbuckle KC, Thorne PS, Robertson LW, Duffel MW. Identification of a sulfate metabolite of PCB 11 in human serum. Environment International. PMID 27816204 DOI: 10.1016/J.Envint.2016.10.023 |
0.579 |
|
2016 |
Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) decreases hepatic and systemic ratios of epoxide to diol metabolites of unsaturated fatty acids in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27208083 DOI: 10.1093/Toxsci/Kfw084 |
0.499 |
|
2016 |
Rodriguez EA, Li X, Lehmler HJ, Robertson LW, Duffel MW. Sulfation of lower chlorinated polychlorinated biphenyls increases their affinity for the major drug-binding sites of human serum albumin. Environmental Science & Technology. PMID 27116425 DOI: 10.1021/Acs.Est.6B00484 |
0.525 |
|
2016 |
Kania-Korwel I, Lehmler HJ. Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a review. Environmental Science and Pollution Research International. 23: 2042-57. PMID 25651810 DOI: 10.1007/S11356-015-4150-2 |
0.344 |
|
2016 |
Jahan S, Carter GS, Krager KJ, Li X, Lehmler H, Aykin-Burns N. Absence of Functional Sirtuin 3 Alters Fatty Acid and Glucose Metabolism Following 4-OH-PCB11 Exposure Free Radical Biology and Medicine. 100: S181. DOI: 10.1016/J.Freeradbiomed.2016.10.475 |
0.329 |
|
2015 |
Ma C, Zhai G, Wu H, Kania-Korwel I, Lehmler HJ, Schnoor JL. Identification of a novel hydroxylated metabolite of 2,2',3,5',6-pentachlorobiphenyl formed in whole poplar plants. Environmental Science and Pollution Research International. PMID 26676542 DOI: 10.1007/S11356-015-5939-8 |
0.311 |
|
2015 |
Zhao H, Jiang J, Wang Y, Lehmler HJ, Buettner GR, Quan X, Chen J. Monohydroxylated Polybrominated Diphenyl Ethers (OH-PBDEs) and Dihydroxylated Polybrominated Biphenyls (di-OH-PBBs): Novel Photoproducts of 2,6-Dibromophenol. Environmental Science & Technology. PMID 26545041 DOI: 10.1021/Acs.Est.5B03637 |
0.302 |
|
2015 |
Hu X, Adamcakova-Dodd A, Lehmler HJ, Gibson-Corley K, Thorne PS. Toxicity Evaluation of Exposure to an Atmospheric Mixture of Polychlorinated Biphenyls by Nose-Only and Whole-Body Inhalation Regimens. Environmental Science & Technology. PMID 26348937 DOI: 10.1021/Acs.Est.5B02865 |
0.351 |
|
2015 |
Flor S, He X, Lehmler HJ, Ludewig G. Estrogenicity and androgenicity screening of PCB sulfate monoesters in human breast cancer MCF-7 cells. Environmental Science and Pollution Research International. PMID 26300354 DOI: 10.1007/S11356-015-5142-Y |
0.375 |
|
2015 |
Grimm FA, He X, Teesch LM, Lehmler HJ, Robertson LW, Duffel MW. Tissue Distribution, Metabolism, and Excretion of 3,3'-Dichloro-4'-sulfooxy-biphenyl in the Rat. Environmental Science & Technology. 49: 8087-95. PMID 26046945 DOI: 10.1021/Acs.Est.5B01499 |
0.559 |
|
2015 |
Grimm FA, Hu D, Kania-Korwel I, Lehmler HJ, Ludewig G, Hornbuckle KC, Duffel MW, Bergman Å, Robertson LW. Metabolism and metabolites of polychlorinated biphenyls. Critical Reviews in Toxicology. 45: 245-72. PMID 25629923 DOI: 10.3109/10408444.2014.999365 |
0.542 |
|
2015 |
Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Modulating inhibitors of transthyretin fibrillogenesis via sulfation: polychlorinated biphenyl sulfates as models. Chemico-Biological Interactions. 228: 1-8. PMID 25595224 DOI: 10.1016/J.Cbi.2015.01.002 |
0.503 |
|
2015 |
Schroer HW, Langenfeld KL, Li X, Lehmler HJ, Just CL. Stable Isotope-Enabled Pathway Elucidation of 2,4-Dinitroanisole Metabolized by Rhizobium lichtii Environmental Science and Technology Letters. 2: 362-366. DOI: 10.1021/Acs.Estlett.5B00278 |
0.33 |
|
2014 |
Aqil F, Shen H, Jeyabalan J, Xin X, Lehmler HJ, Ludewig G, Robertson LW, Gupta RC. Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants. Toxicology Reports. 1: 820-833. PMID 25530946 DOI: 10.1016/J.Toxrep.2014.09.010 |
0.536 |
|
2014 |
Zhai G, Gutowski SM, Lehmler HJ, Schnoor JL. Enantioselective transport and biotransformation of chiral hydroxylated metabolites of polychlorinated biphenyls in whole poplar plants. Environmental Science & Technology. 48: 12213-20. PMID 25238141 DOI: 10.1021/Es503443E |
0.359 |
|
2014 |
Dhakal K, Uwimana E, Adamcakova-Dodd A, Thorne PS, Lehmler HJ, Robertson LW. Disposition of phenolic and sulfated metabolites after inhalation exposure to 4-chlorobiphenyl (PCB3) in female rats. Chemical Research in Toxicology. 27: 1411-20. PMID 24988477 DOI: 10.1021/Tx500150H |
0.536 |
|
2014 |
Li X, Parkin S, Lehmler HJ. 2,4-Di-chloro-1-iodo-6-nitro-benzene. Acta Crystallographica. Section E, Structure Reports Online. 70: o607. PMID 24860400 DOI: 10.1107/S1600536814008733 |
0.33 |
|
2014 |
Ekuase EJ, Lehmler HJ, Robertson LW, Duffel MW. Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1. Chemico-Biological Interactions. 212: 56-64. PMID 24508592 DOI: 10.1016/J.Cbi.2014.01.018 |
0.524 |
|
2014 |
Wu X, Kammerer A, Lehmler HJ. Microsomal oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) results in species-dependent chiral signatures of the hydroxylated metabolites. Environmental Science & Technology. 48: 2436-44. PMID 24467194 DOI: 10.1021/Es405433T |
0.348 |
|
2013 |
Zhai G, Wu X, Lehmler HJ, Schnoor JL. Atropisomeric determination of chiral hydroxylated metabolites of polychlorinated biphenyls using HPLC-MS. Chemistry Central Journal. 7: 183. PMID 24360245 DOI: 10.1186/1752-153X-7-183 |
0.337 |
|
2013 |
Lu Z, Kania-Korwel I, Lehmler HJ, Wong CS. Stereoselective formation of mono- and dihydroxylated polychlorinated biphenyls by rat cytochrome P450 2B1. Environmental Science & Technology. 47: 12184-92. PMID 24060104 DOI: 10.1021/Es402838F |
0.388 |
|
2013 |
Qin X, Lehmler HJ, Teesch LM, Robertson LW, Duffel MW. Chlorinated biphenyl quinones and phenyl-2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1. Chemical Research in Toxicology. 26: 1474-85. PMID 24059442 DOI: 10.1021/Tx400207Q |
0.565 |
|
2013 |
Zhu Y, Mapuskar KA, Marek RF, Xu W, Lehmler HJ, Robertson LW, Hornbuckle KC, Spitz DR, Aykin-Burns N. A new player in environmentally induced oxidative stress: polychlorinated biphenyl congener, 3,3'-dichlorobiphenyl (PCB11). Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 39-50. PMID 23997111 DOI: 10.1093/Toxsci/Kft186 |
0.509 |
|
2013 |
Lehmler HJ, He X, Li X, Duffel MW, Parkin S. Effective synthesis of sulfate metabolites of chlorinated phenols. Chemosphere. 93: 1965-71. PMID 23906814 DOI: 10.1016/J.Chemosphere.2013.06.087 |
0.337 |
|
2013 |
Kania-Korwel I, Lehmler HJ. Chlordane and heptachlor are metabolized enantioselectively by rat liver microsomes. Environmental Science & Technology. 47: 8913-22. PMID 23799267 DOI: 10.1021/Es401916A |
0.373 |
|
2013 |
Lehmler HJ, Wu H, Parkin S. 2,2',5',6-Tetra-chloro-4-[(1S)-1-methyl-prop-oxy]biphen-yl. Acta Crystallographica. Section E, Structure Reports Online. 69: o983. PMID 23795135 DOI: 10.1107/S1600536813014098 |
0.319 |
|
2013 |
Lehmler HJ, Wu H, Parkin S. 5,5'-Dichloro-2,2'-dimeth-oxy-biphen-yl. Acta Crystallographica. Section E, Structure Reports Online. 69: o650. PMID 23723814 DOI: 10.1107/S160053681300826X |
0.316 |
|
2013 |
Dhakal K, Adamcakova-Dodd A, Lehmler HJ, Thorne PS, Robertson LW. Sulfate conjugates are urinary markers of inhalation exposure to 4-chlorobiphenyl (PCB3). Chemical Research in Toxicology. 26: 853-5. PMID 23713983 DOI: 10.1021/Tx4001539 |
0.492 |
|
2013 |
Lehmler HJ, He X, Duffel MW, Parkin S. 3,4',5-Trichloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 69: o620. PMID 23634142 DOI: 10.1107/S1600536813007976 |
0.348 |
|
2013 |
Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environmental Health Perspectives. 121: 657-62. PMID 23584369 DOI: 10.1289/Ehp.1206198 |
0.51 |
|
2013 |
Hu X, Lehmler HJ, Adamcakova-Dodd A, Thorne PS. Elimination of inhaled 3,3'-dichlorobiphenyl and the formation of the 4-hydroxylated metabolite. Environmental Science & Technology. 47: 4743-51. PMID 23582014 DOI: 10.1021/Es3049114 |
0.363 |
|
2013 |
Rignall B, Grote K, Gavrilov A, Weimer M, Kopp-Schneider A, Krause E, Appel KE, Buchmann A, Robertson LW, Lehmler HJ, Kania-Korwel I, Chahoud I, Schwarz M. Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 29-41. PMID 23457121 DOI: 10.1093/Toxsci/Kft034 |
0.465 |
|
2013 |
Kania-Korwel I, Lehmler HJ. Assigning atropisomer elution orders using atropisomerically enriched polychlorinated biphenyl fractions generated by microsomal metabolism. Journal of Chromatography. A. 1278: 133-44. PMID 23347976 DOI: 10.1016/J.Chroma.2012.12.041 |
0.328 |
|
2013 |
Zhai G, Lehmler HJ, Schnoor JL. Inhibition of cytochromes P450 and the hydroxylation of 4-monochlorobiphenyl in whole poplar. Environmental Science & Technology. 47: 6829-35. PMID 23320482 DOI: 10.1021/Es304298M |
0.332 |
|
2013 |
Zhai G, Lehmler HJ, Schnoor JL. Sulfate metabolites of 4-monochlorobiphenyl in whole poplar plants. Environmental Science & Technology. 47: 557-62. PMID 23215248 DOI: 10.1021/Es303807F |
0.354 |
|
2012 |
Dhakal K, He X, Lehmler HJ, Teesch LM, Duffel MW, Robertson LW. Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats. Chemical Research in Toxicology. 25: 2796-804. PMID 23137097 DOI: 10.1021/Tx300416V |
0.536 |
|
2012 |
Hu X, Adamcakova-Dodd A, Lehmler HJ, Hu D, Hornbuckle K, Thorne PS. Subchronic inhalation exposure study of an airborne polychlorinated biphenyl mixture resembling the Chicago ambient air congener profile. Environmental Science & Technology. 46: 9653-62. PMID 22846166 DOI: 10.1021/Es301129H |
0.346 |
|
2012 |
Ambati J, Song Y, Rankin SE, Lehmler HJ. Density functional theory study of semiquinone radical anions of polychlorinated biphenyls in the syn- and anti-like conformation. The Journal of Physical Chemistry. A. 116: 1586-95. PMID 22257259 DOI: 10.1021/Jp2077193 |
0.335 |
|
2011 |
Zhai G, Lehmler HJ, Schnoor JL. New hydroxylated metabolites of 4-monochlorobiphenyl in whole poplar plants. Chemistry Central Journal. 5: 87. PMID 22185578 DOI: 10.1186/1752-153X-5-87 |
0.346 |
|
2011 |
Bunaciu RP, Tharappel JC, Lehmler HJ, Lee EY, Robertson LW, Bruckner GG, Spear BT, Glauert HP. Role of oil vehicle on hepatic cell proliferation in PCB-treated rats. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 30: 273-82. PMID 22181977 DOI: 10.1615/Jenvironpatholtoxicoloncol.V30.I4.10 |
0.478 |
|
2011 |
Wu X, Pramanik A, Duffel MW, Hrycay EG, Bandiera SM, Lehmler HJ, Kania-Korwel I. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes. Chemical Research in Toxicology. 24: 2249-57. PMID 22026639 DOI: 10.1021/Tx200360M |
0.408 |
|
2011 |
Kania-Korwel I, Duffel MW, Lehmler HJ. Gas chromatographic analysis with chiral cyclodextrin phases reveals the enantioselective formation of hydroxylated polychlorinated biphenyls by rat liver microsomes. Environmental Science & Technology. 45: 9590-6. PMID 21966948 DOI: 10.1021/Es2014727 |
0.384 |
|
2011 |
Joshi SN, Vyas SM, Wu H, Duffel MW, Parkin S, Lehmler HJ. Regioselective Iodination of Chlorinated Aromatic Compounds Using Silver Salts. Tetrahedron. 67: 7461-7469. PMID 21918585 DOI: 10.1016/J.Tet.2011.07.064 |
0.323 |
|
2011 |
Ekuase EJ, Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 24: 1720-8. PMID 21913674 DOI: 10.1021/Tx200260H |
0.559 |
|
2011 |
Song Y, Ambati J, Parkin S, Rankin SE, Robertson LW, Lehmler HJ. Crystal structure and density functional theory studies of toxic quinone metabolites of polychlorinated biphenyls. Chemosphere. 85: 386-92. PMID 21824639 DOI: 10.1016/J.Chemosphere.2011.07.004 |
0.578 |
|
2011 |
Senthilkumar PK, Klingelhutz AJ, Jacobus JA, Lehmler H, Robertson LW, Ludewig G. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicology Letters. 204: 64-70. PMID 21530622 DOI: 10.1016/J.Toxlet.2011.04.012 |
0.77 |
|
2011 |
Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1). Chemico-Biological Interactions. 189: 153-60. PMID 21130751 DOI: 10.1016/J.Cbi.2010.11.009 |
0.515 |
|
2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. 4'-Chloro-biphenyl-3-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o2306. PMID 21588655 DOI: 10.1107/S1600536810031338 |
0.554 |
|
2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. 3',4'-Dichloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o1615-6. PMID 21587847 DOI: 10.1107/S1600536810020362 |
0.502 |
|
2010 |
Song Y, Parkin S, Lehmler HJ. 1-Bromo-2-chloro-4,5-dimethoxy-benzene. Acta Crystallographica. Section E, Structure Reports Online. 66: o813. PMID 21580645 DOI: 10.1107/S1600536810008445 |
0.345 |
|
2010 |
Song Y, Parkin S, Lehmler HJ. 1-Bromo-2,3,6-trichloro-4,5-dimethoxy-benzene. Acta Crystallographica. Section E, Structure Reports Online. 66: o487. PMID 21579894 DOI: 10.1107/S1600536810002977 |
0.341 |
|
2010 |
Song Y, Parkin S, Lehmler HJ. 1-Bromo-4-chloro-2,5-dimethoxy-benzene. Acta Crystallographica. Section E, Structure Reports Online. 66: o339. PMID 21579768 DOI: 10.1107/S1600536810000504 |
0.339 |
|
2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. Biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o1073. PMID 21579128 DOI: 10.1107/S1600536810012845 |
0.565 |
|
2010 |
Zhai G, Lehmler HJ, Schnoor JL. Identification of hydroxylated metabolites of 3,3',4,4'-tetrachlorobiphenyl and metabolic pathway in whole poplar plants. Chemosphere. 81: 523-8. PMID 20708213 DOI: 10.1016/J.Chemosphere.2010.07.036 |
0.345 |
|
2010 |
Hu X, Adamcakova-Dodd A, Lehmler HJ, Hu D, Kania-Korwel I, Hornbuckle KC, Thorne PS. Time course of congener uptake and elimination in rats after short-term inhalation exposure to an airborne polychlorinated biphenyl (PCB) mixture. Environmental Science & Technology. 44: 6893-900. PMID 20698547 DOI: 10.1021/Es101274B |
0.327 |
|
2010 |
Kania-Korwel I, El-Komy MH, Veng-Pedersen P, Lehmler HJ. Clearance of polychlorinated biphenyl atropisomers is enantioselective in female C57Bl/6 mice. Environmental Science & Technology. 44: 2828-35. PMID 20384376 DOI: 10.1021/Es901781P |
0.318 |
|
2010 |
Chan K, Lehmler HJ, Sivagnanam M, Feng CY, Robertson L, O'Brien PJ. Cytotoxic effects of polychlorinated biphenyl hydroquinone metabolites in rat hepatocytes. Journal of Applied Toxicology : Jat. 30: 163-71. PMID 19830680 DOI: 10.1002/Jat.1483 |
0.558 |
|
2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. An efficient approach to sulfate metabolites of polychlorinated biphenyls. Environment International. 36: 843-8. PMID 19345419 DOI: 10.1016/J.Envint.2009.02.005 |
0.577 |
|
2010 |
Telu S, Parkin S, Robertson LW, Lehmler HJ. Improved syntheses of non-dioxin-like polychlorinated biphenyls (PCBs) and some of their sulfur-containing metabolites. Environment International. 36: 828-34. PMID 19261331 DOI: 10.1016/J.Envint.2009.01.013 |
0.545 |
|
2009 |
Dreiem A, Rykken S, Lehmler HJ, Robertson LW, Fonnum F. Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells. Toxicology and Applied Pharmacology. 240: 306-13. PMID 19631230 DOI: 10.1016/J.Taap.2009.07.016 |
0.569 |
|
2009 |
Xie W, Wu Q, Kania-Korwel I, Tharappel JC, Telu S, Coleman MC, Glauert HP, Kannan K, Mariappan SV, Spitz DR, Weydert J, Lehmler HJ. Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats. Archives of Toxicology. 83: 909-24. PMID 19544052 DOI: 10.1007/S00204-009-0450-Y |
0.324 |
|
2009 |
Song Y, Wagner BA, Witmer JR, Lehmler HJ, Buettner GR. Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones. Proceedings of the National Academy of Sciences of the United States of America. 106: 9725-30. PMID 19497881 DOI: 10.1073/Pnas.0810352106 |
0.329 |
|
2009 |
Li X, Robertson LW, Lehmler HJ. Electron ionization mass spectral fragmentation study of sulfation derivatives of polychlorinated biphenyls. Chemistry Central Journal. 3: 5. PMID 19272150 DOI: 10.1186/1752-153X-3-5 |
0.534 |
|
2009 |
Spencer WA, Lehmler HJ, Robertson LW, Gupta RC. Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species. Free Radical Biology & Medicine. 46: 1346-52. PMID 19233261 DOI: 10.1016/J.Freeradbiomed.2009.02.005 |
0.512 |
|
2009 |
Liu Y, Smart JT, Song Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1065-72. PMID 19196841 DOI: 10.1124/Dmd.108.026021 |
0.562 |
|
2009 |
Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chemical Research in Toxicology. 22: 201-7. PMID 18954145 DOI: 10.1021/Tx800328U |
0.466 |
|
2008 |
Li X, Parkin S, Robertson LW, Lehmler HJ. 4'-Chloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 64: o2464. PMID 21581432 DOI: 10.1107/S1600536808038865 |
0.508 |
|
2008 |
Lehmler HJ, Parkin S. 5-Fluoro-1-(3-metylbutano-yl)pyrimidine-2,4(1H,3H)-dione. Acta Crystallographica. Section E, Structure Reports Online. 64: o703. PMID 21202094 DOI: 10.1107/S1600536808006296 |
0.343 |
|
2008 |
Lehmler HJ, Parkin S. 5-Fluoro-1-(penta-noyl)pyrimidine-2,4(1H,3H)-dione. Acta Crystallographica. Section E, Structure Reports Online. 64: o617. PMID 21201951 DOI: 10.1107/S1600536808004418 |
0.341 |
|
2008 |
Telu S, Parkin S, Robertson LW, Lehmler HJ. 1,3,5-Trichloro-2-methoxy-benzene. Acta Crystallographica. Section E, Structure Reports Online. 64: o424. PMID 21201451 DOI: 10.1107/S160053680800055X |
0.554 |
|
2008 |
Glauert HP, Tharappel JC, Lu Z, Stemm D, Banerjee S, Chan LS, Lee EY, Lehmler HJ, Robertson LW, Spear BT. Role of oxidative stress in the promoting activities of pcbs. Environmental Toxicology and Pharmacology. 25: 247-50. PMID 19122744 DOI: 10.1016/J.Etap.2007.10.025 |
0.51 |
|
2008 |
Song Y, Buettner GR, Parkin S, Wagner BA, Robertson LW, Lehmler HJ. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones. The Journal of Organic Chemistry. 73: 8296-304. PMID 18839991 DOI: 10.1021/Jo801397G |
0.563 |
|
2008 |
Tharappel JC, Lehmler HJ, Srinivasan C, Robertson LW, Spear BT, Glauert HP. Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 3467-74. PMID 18796325 DOI: 10.1016/J.Fct.2008.08.023 |
0.522 |
|
2008 |
Kania-Korwel I, Vyas SM, Song Y, Lehmler HJ. Gas chromatographic separation of methoxylated polychlorinated biphenyl atropisomers. Journal of Chromatography. A. 1207: 146-54. PMID 18760792 DOI: 10.1016/J.Chroma.2008.08.044 |
0.351 |
|
2008 |
Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radical Biology & Medicine. 45: 1094-102. PMID 18691649 DOI: 10.1016/J.Freeradbiomed.2008.07.007 |
0.521 |
|
2008 |
Glauert HP, Tharappel JC, Banerjee S, Chan NL, Kania-Korwel I, Lehmler HJ, Lee EY, Robertson LW, Spear BT. Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice. Toxicology and Applied Pharmacology. 232: 302-8. PMID 18644402 DOI: 10.1016/J.Taap.2008.06.013 |
0.482 |
|
2008 |
Kania-Korwel I, Xie W, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes. Archives of Environmental Contamination and Toxicology. 55: 510-7. PMID 18437444 DOI: 10.1007/S00244-007-9111-4 |
0.536 |
|
2008 |
Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler HJ. Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice. Environmental Toxicology and Chemistry / Setac. 27: 299-305. PMID 18348647 DOI: 10.1897/07-359R.1 |
0.537 |
|
2008 |
Stemm DN, Tharappel JC, Lehmler HJ, Srinivasan C, Morris JS, Spate VL, Robertson LW, Spear BT, Glauert HP. Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl. Experimental Biology and Medicine (Maywood, N.J.). 233: 366-76. PMID 18296742 DOI: 10.3181/0708-Rm-211 |
0.532 |
|
2008 |
Sacco JC, Lehmler HJ, Robertson LW, Li W, James MO. Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 623-30. PMID 18180271 DOI: 10.1124/Dmd.107.019596 |
0.528 |
|
2007 |
Shaikh NS, Parkin S, Luthe G, Lehmler HJ. The three-dimensional structure of 3,3',4,4'-tetrachlorobiphenyl, a dioxin-like polychlorinated biphenyl (PCB). Chemosphere. 70: 1694-8. PMID 17723240 DOI: 10.1016/J.Chemosphere.2007.07.017 |
0.318 |
|
2007 |
Bunaciu RP, Tharappel JC, Lehmler HJ, Kania-Korwel I, Robertson LW, Srinivasan C, Spear BT, Glauert HP. The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats. Toxicology. 239: 147-55. PMID 17703865 DOI: 10.1016/J.Tox.2007.06.102 |
0.535 |
|
2007 |
Sadeghi-Aliabadi H, Chan K, Lehmler HJ, Robertson LW, O'Brien PJ. Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. Chemico-Biological Interactions. 167: 184-92. PMID 17408604 DOI: 10.1016/J.Cbi.2007.02.011 |
0.578 |
|
2007 |
Vyas SM, Kania-Korwel I, Lehmler HJ. Differences in the isomer composition of perfluoroctanesulfonyl (PFOS) derivatives. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 42: 249-55. PMID 17365291 DOI: 10.1080/10934520601134031 |
0.327 |
|
2007 |
Kania-Korwel I, Shaikh NS, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration. Chirality. 19: 56-66. PMID 17089340 DOI: 10.1002/Chir.20342 |
0.519 |
|
2007 |
Shaikh NS, Parkin S, Lehmler H. Tetrakis(2,4,5-trichlorophenyl)stannane Acta Crystallographica Section E Structure Reports Online. 63: m1584-m1586. DOI: 10.1107/S1600536807020909 |
0.306 |
|
2007 |
Song Y, Parkin S, Lehmler H. 4-Bromo-2-chloro-1-methoxybenzene Acta Crystallographica Section E Structure Reports Online. 63: o2091-o2092. DOI: 10.1107/S1600536807013372 |
0.376 |
|
2006 |
Liu Y, Apak TI, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 19: 1420-5. PMID 17112228 DOI: 10.1021/TX060160+ |
0.561 |
|
2006 |
Ptak A, Ludewig G, Kapiszewska M, Magnowska Z, Lehmler HJ, Robertson LW, Gregoraszczuk EL. Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. Toxicology Letters. 166: 200-11. PMID 16949219 DOI: 10.1016/J.Toxlet.2006.07.304 |
0.566 |
|
2006 |
Kania-Korwel I, Garrison AW, Avants JK, Hornbuckle KC, Robertson LW, Sulkowski WW, Lehmler HJ. Distribution of chiral PCBs in selected tissues in the laboratory rat. Environmental Science & Technology. 40: 3704-10. PMID 16830530 DOI: 10.1021/Es0602086 |
0.522 |
|
2006 |
Kunz S, Schwarz M, Schilling B, Päpke O, Lehmler HJ, Robertson LW, Schrenk D, Schmitz HJ. Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicology Letters. 164: 133-43. PMID 16426774 DOI: 10.1016/J.Toxlet.2005.12.003 |
0.516 |
|
2006 |
Wang LQ, Lehmler HJ, Robertson LW, James MO. Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate. Chemico-Biological Interactions. 159: 235-46. PMID 16413005 DOI: 10.1016/J.Cbi.2005.12.004 |
0.538 |
|
2006 |
Ptak A, Ludewig G, Robertson L, Lehmler HJ, Gregoraszczuk EL. In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity. Toxicology Letters. 164: 113-22. PMID 16412591 DOI: 10.1016/J.Toxlet.2005.12.001 |
0.565 |
|
2006 |
Vyas SM, Parkin S, Robertson LW, Lehmler H. 2,5-Dichloro-4′-methoxybiphenyl Acta Crystallographica Section E Structure Reports Online. 62: o4162-o4163. DOI: 10.1107/S1600536806033319 |
0.547 |
|
2006 |
Vyas SM, Parkin S, Robertson LW, Lehmler H. 4-Chloro-2′,3′-dimethoxybiphenyl Acta Crystallographica Section E Structure Reports Online. 62: o3639-o3640. DOI: 10.1107/S1600536806028923 |
0.548 |
|
2006 |
Vyas SM, Parkin S, Lehmler H. 2,2′,3,4,4′,5,5′-Heptachlorobiphenyl (PCB 180) Acta Crystallographica Section E Structure Reports Online. 62: o2905-o2906. DOI: 10.1107/S1600536806022240 |
0.345 |
|
2006 |
Vyas SM, Turánek J, Knötigová P, Kašná A, Kvardová V, Koganti V, Rankin SE, Knutson BL, Lehmler HJ. Synthesis and biocompatibility evaluation of partially fluorinated pyridinium bromides New Journal of Chemistry. 30: 944-951. DOI: 10.1039/B516039A |
0.32 |
|
2005 |
Kania-Korwel I, Hornbuckle KC, Peck A, Ludewig G, Robertson LW, Sulkowski WW, Espandiari P, Gairola CG, Lehmler HJ. Congener-specific tissue distribution of aroclor 1254 and a highly chlorinated environmental PCB mixture in rats. Environmental Science & Technology. 39: 3513-20. PMID 15954224 DOI: 10.1021/Es047987F |
0.515 |
|
2005 |
Wang LQ, Lehmler HJ, Robertson LW, Falany CN, James MO. In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols. Environmental Health Perspectives. 113: 680-7. PMID 15929889 DOI: 10.1289/Ehp.7837 |
0.546 |
|
2005 |
Ptak A, Ludewig G, Lehmler HJ, Wójtowicz AK, Robertson LW, Gregoraszczuk EL. Comparison of the actions of 4-chlorobiphenyl and its hydroxylated metabolites on estradiol secretion by ovarian follicles in primary cells in culture. Reproductive Toxicology (Elmsford, N.Y.). 20: 57-64. PMID 15808786 DOI: 10.1016/J.Reprotox.2004.12.003 |
0.549 |
|
2005 |
Lehmler HJ, Robertson LW, Garrison AW, Kodavanti PR. Effects of PCB 84 enantiomers on [3H]-phorbol ester binding in rat cerebellar granule cells and 45Ca2+-uptake in rat cerebellum. Toxicology Letters. 156: 391-400. PMID 15763638 DOI: 10.1016/J.Toxlet.2004.12.011 |
0.52 |
|
2005 |
Glauert HP, Lu Z, Kumar A, Bunaciu RP, Patel S, Tharappel JC, Stemm DN, Lehmler HJ, Lee EY, Robertson LW, Spear BT. Dietary vitamin E does not inhibit the promotion of liver carcinogenesis by polychlorinated biphenyls in rats. The Journal of Nutrition. 135: 283-6. PMID 15671227 DOI: 10.1093/Jn/135.2.283 |
0.506 |
|
2004 |
Kania-Korwel I, Parkin S, Robertson LW, Lehmler HJ. Synthesis of polychlorinated biphenyls and their metabolites with a modified Suzuki-coupling. Chemosphere. 56: 735-44. PMID 15251288 DOI: 10.1016/J.Chemosphere.2004.04.035 |
0.512 |
|
2004 |
Gauger KJ, Kato Y, Haraguchi K, Lehmler HJ, Robertson LW, Bansal R, Zoeller RT. Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors. Environmental Health Perspectives. 112: 516-23. PMID 15064154 DOI: 10.1289/Ehp.6672 |
0.528 |
|
2004 |
Machala M, Bláha L, Lehmler HJ, Plísková M, Májková Z, Kapplová P, Sovadinová I, Vondrácek J, Malmberg T, Robertson LW. Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells. Chemical Research in Toxicology. 17: 340-7. PMID 15025504 DOI: 10.1021/Tx030034V |
0.563 |
|
2004 |
Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW. Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 41-6. PMID 14976334 DOI: 10.1093/Toxsci/Kfh097 |
0.571 |
|
2004 |
Kania-Korwel I, Parkin S, Robertson LW, Lehmler H. 2,4,5-Trichlorobiphenyl Acta Crystallographica Section E Structure Reports Online. 60: o1652-o1653. DOI: 10.1107/S1600536804020975 |
0.545 |
|
2003 |
Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW. Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model. Toxicology and Applied Pharmacology. 186: 55-62. PMID 12583993 DOI: 10.1016/S0041-008X(02)00018-2 |
0.539 |
|
2003 |
Arif JM, Lehmler HJ, Robertson LW, Gupta RC. Interaction of benzoquinone- and hydroquinone-derivatives of lower chlorinated biphenyls with DNA and nucleotides in vitro. Chemico-Biological Interactions. 142: 307-16. PMID 12453668 DOI: 10.1016/S0009-2797(02)00141-2 |
0.496 |
|
2003 |
Kania-Korwel I, Robertson LW, Lehmler H, Parkin S. 2,4,6-Trichloroiodobenzene Acta Crystallographica Section E Structure Reports Online. 59: o1770-o1771. DOI: 10.1107/S1600536803022530 |
0.487 |
|
2003 |
Kania-Korwel I, Lehmler H, Robertson LW, Parkin S. 2,4,5-Trichloro-1-iodobenzene Acta Crystallographica Section E Structure Reports Online. 59: o1048-o1049. DOI: 10.1107/S1600536803013977 |
0.492 |
|
2002 |
Tampal N, Lehmler HJ, Espandiari P, Malmberg T, Robertson LW. Glucuronidation of hydroxylated polychlorinated biphenyls (PCBs). Chemical Research in Toxicology. 15: 1259-66. PMID 12387623 DOI: 10.1021/Tx0200212 |
0.563 |
|
2002 |
van den Hurk P, Kubiczak GA, Lehmler HJ, James MO. Hydroxylated polychlorinated biphenyls as inhibitors of the sulfation and glucuronidation of 3-hydroxy-benzo[a]pyrene. Environmental Health Perspectives. 110: 343-8. PMID 11940451 DOI: 10.1289/Ehp.02110343 |
0.346 |
|
2002 |
Lehmler HJ, Parkin S, Robertson LW. The three-dimensional structure of 3, 3', 5'-trichloro-4-methoxybiphenyl, a "coplanar" polychlorinated biphenyl (PCB) derivative. Chemosphere. 46: 485-8. PMID 11829405 DOI: 10.1016/S0045-6535(01)00177-1 |
0.539 |
|
2002 |
Lehmler HJ, Robertson LW, Parkin S, Brock CP. Z' = 4 structure without obvious pseudosymmetry: implications for the formation of solid-state compounds. Acta Crystallographica. Section B, Structural Science. 58: 140-7. PMID 11818662 DOI: 10.1107/S0108768101018043 |
0.53 |
|
2002 |
Lehmler HJ, Robertson LW. Synthesis of hydroxylated PCB metabolites with the Suzuki-coupling. Chemosphere. 45: 1119-27. PMID 11695625 DOI: 10.1016/S0045-6535(01)00052-2 |
0.53 |
|
2002 |
Lehmler HJ, Robertson LW. Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-coupling. Chemosphere. 45: 137-43. PMID 11572605 DOI: 10.1016/S0045-6535(00)00546-4 |
0.49 |
|
2002 |
Lehmler H, Robertson LW, Parkin S. 2-(3,5-Dichlorophenyl)-1,4-benzoquinone Acta Crystallographica Section E Structure Reports Online. 58: o366-o367. DOI: 10.1107/S160053680200291X |
0.535 |
|
2001 |
Srinivasan A, Lehmler HJ, Robertson LW, Ludewig G. Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites. Toxicological Sciences : An Official Journal of the Society of Toxicology. 60: 92-102. PMID 11222876 DOI: 10.1093/Toxsci/60.1.92 |
0.533 |
|
2001 |
Lehmler H, Robertson LW, Parkin S. 4-Chloro-3′,4′-dihydroxybiphenyl Acta Crystallographica Section E Structure Reports Online. 57: o590-o591. DOI: 10.1107/S1600536801008844 |
0.548 |
|
2001 |
Lehmler H, Parkin S, Robertson LW. 2,3,4′-Trichlorobiphenyl Acta Crystallographica Section E Structure Reports Online. 57: o111-o112. DOI: 10.1107/S1600536800021127 |
0.477 |
|
2000 |
Lehmler H, Parkin S. 5-Fluoro-1-octanoyluracil Acta Crystallographica Section C Crystal Structure Communications. 56: e518-e519. DOI: 10.1107/S0108270100013056 |
0.311 |
|
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