Year |
Citation |
Score |
2018 |
Ramasamy V, Arora U, Shukla R, Poddar A, Shanmugam RK, White LJ, Mattocks MM, Raut R, Perween A, Tyagi P, de Silva AM, Bhaumik SK, Kaja MK, Villinger F, Ahmed R, ... Johnston RE, et al. A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice. Plos Neglected Tropical Diseases. 12: e0006191. PMID 29309412 DOI: 10.1371/Journal.Pntd.0006191 |
0.34 |
|
2016 |
Bates JT, Pickens JA, Schuster JE, Johnson M, Tollefson SJ, Williams JV, Davis NL, Johnston RE, Schultz-Darken N, Slaughter JC, Smith-House F, Crowe JE. Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates. Vaccine. PMID 26772634 DOI: 10.1016/J.Vaccine.2015.12.045 |
0.369 |
|
2014 |
Khalil SM, Tonkin DR, Snead AT, Parks GD, Johnston RE, White LJ. An alphavirus-based adjuvant enhances serum and mucosal antibodies, T cells, and protective immunity to influenza virus in neonatal mice. Journal of Virology. 88: 9182-96. PMID 24899195 DOI: 10.1128/Jvi.00327-14 |
0.365 |
|
2014 |
Khalil SM, Tonkin DR, Mattocks MD, Snead AT, Johnston RE, White LJ. A tetravalent alphavirus-vector based dengue vaccine provides effective immunity in an early life mouse model. Vaccine. 32: 4068-74. PMID 24882043 DOI: 10.1016/j.vaccine.2014.05.053 |
0.33 |
|
2013 |
Zellweger RM, Miller R, Eddy WE, White LJ, Johnston RE, Shresta S. Role of humoral versus cellular responses induced by a protective dengue vaccine candidate. Plos Pathogens. 9: e1003723. PMID 24204271 DOI: 10.1371/journal.ppat.1003723 |
0.318 |
|
2013 |
White LJ, Sariol CA, Mattocks MD, Wahala M P B W, Yingsiwaphat V, Collier ML, Whitley J, Mikkelsen R, Rodriguez IV, Martinez MI, de Silva A, Johnston RE. An alphavirus vector-based tetravalent dengue vaccine induces a rapid and protective immune response in macaques that differs qualitatively from immunity induced by live virus infection. Journal of Virology. 87: 3409-24. PMID 23302884 DOI: 10.1128/JVI.02298-12 |
0.363 |
|
2012 |
Tonkin DR, Whitmore A, Johnston RE, Barro M. Infected dendritic cells are sufficient to mediate the adjuvant activity generated by Venezuelan equine encephalitis virus replicon particles. Vaccine. 30: 4532-42. PMID 22531556 DOI: 10.1016/J.Vaccine.2012.04.030 |
0.361 |
|
2012 |
Brooke CB, Schäfer A, Matsushima GK, White LJ, Johnston RE. Early activation of the host complement system is required to restrict central nervous system invasion and limit neuropathology during Venezuelan equine encephalitis virus infection. The Journal of General Virology. 93: 797-806. PMID 22205717 DOI: 10.1099/Vir.0.038281-0 |
0.496 |
|
2012 |
Jurgens CK, Young KR, Madden VJ, Johnson PR, Johnston RE. A novel self-replicating chimeric lentivirus-like particle. Journal of Virology. 86: 246-61. PMID 22013035 DOI: 10.1128/Jvi.05191-11 |
0.384 |
|
2011 |
Schäfer A, Brooke CB, Whitmore AC, Johnston RE. The role of the blood-brain barrier during Venezuelan equine encephalitis virus infection. Journal of Virology. 85: 10682-90. PMID 21849461 DOI: 10.1128/Jvi.05032-11 |
0.477 |
|
2011 |
Carroll TD, Matzinger SR, Barro M, Fritts L, McChesney MB, Miller CJ, Johnston RE. Alphavirus replicon-based adjuvants enhance the immunogenicity and effectiveness of Fluzone ® in rhesus macaques. Vaccine. 29: 931-40. PMID 21111777 DOI: 10.1016/J.Vaccine.2010.11.024 |
0.449 |
|
2011 |
Sheahan T, Whitmore A, Long K, Ferris M, Rockx B, Funkhouser W, Donaldson E, Gralinski L, Collier M, Heise M, Davis N, Johnston R, Baric RS. Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. Journal of Virology. 85: 217-30. PMID 20980507 DOI: 10.1128/Jvi.01805-10 |
0.44 |
|
2010 |
Burgents JE, Moran TP, West ML, Davis NL, Johnston RE, Serody JS. The immunosuppressive tumor environment is the major impediment to successful therapeutic vaccination in Neu transgenic mice. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 482-91. PMID 20463599 DOI: 10.1097/Cji.0B013E3181D756Bb |
0.342 |
|
2010 |
Tonkin DR, Jorquera P, Todd T, Beard CW, Johnston RE, Barro M. Alphavirus replicon-based enhancement of mucosal and systemic immunity is linked to the innate response generated by primary immunization. Vaccine. 28: 3238-46. PMID 20184975 DOI: 10.1016/J.Vaccine.2010.02.010 |
0.391 |
|
2010 |
Brooke CB, Deming DJ, Whitmore AC, White LJ, Johnston RE. T cells facilitate recovery from Venezuelan equine encephalitis virus-induced encephalomyelitis in the absence of antibody. Journal of Virology. 84: 4556-68. PMID 20181704 DOI: 10.1128/Jvi.02545-09 |
0.464 |
|
2010 |
Cruz CC, Suthar MS, Montgomery SA, Shabman R, Simmons J, Johnston RE, Morrison TE, Heise MT. Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein. Virology. 399: 1-10. PMID 20097400 DOI: 10.1016/J.Virol.2009.12.031 |
0.502 |
|
2010 |
Lindesmith LC, Donaldson E, Leon J, Moe CL, Frelinger JA, Johnston RE, Weber DJ, Baric RS. Heterotypic humoral and cellular immune responses following Norwalk virus infection. Journal of Virology. 84: 1800-15. PMID 20007270 DOI: 10.1128/Jvi.02179-09 |
0.422 |
|
2009 |
Konopka JL, Thompson JM, Whitmore AC, Webb DL, Johnston RE. Acute infection with venezuelan equine encephalitis virus replicon particles catalyzes a systemic antiviral state and protects from lethal virus challenge. Journal of Virology. 83: 12432-42. PMID 19793821 DOI: 10.1128/Jvi.00564-09 |
0.518 |
|
2009 |
Simmons JD, White LJ, Morrison TE, Montgomery SA, Whitmore AC, Johnston RE, Heise MT. Venezuelan equine encephalitis virus disrupts STAT1 signaling by distinct mechanisms independent of host shutoff. Journal of Virology. 83: 10571-81. PMID 19656875 DOI: 10.1128/Jvi.01041-09 |
0.421 |
|
2009 |
Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS. Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. Journal of Virology. 83: 6689-705. PMID 19369340 DOI: 10.1128/Jvi.02220-08 |
0.359 |
|
2009 |
Schäfer A, Whitmore AC, Konopka JL, Johnston RE. Replicon particles of Venezuelan equine encephalitis virus as a reductionist murine model for encephalitis. Journal of Virology. 83: 4275-86. PMID 19225006 DOI: 10.1128/Jvi.02383-08 |
0.447 |
|
2009 |
LoBue AD, Thompson JM, Lindesmith L, Johnston RE, Baric RS. Alphavirus-adjuvanted norovirus-like particle vaccines: heterologous, humoral, and mucosal immune responses protect against murine norovirus challenge. Journal of Virology. 83: 3212-27. PMID 19176631 DOI: 10.1128/Jvi.01650-08 |
0.416 |
|
2008 |
Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 19944-9. PMID 19036930 DOI: 10.1073/Pnas.0808116105 |
0.367 |
|
2008 |
Barefoot B, Thornburg NJ, Barouch DH, Yu JS, Sample C, Johnston RE, Liao HX, Kepler TB, Haynes BF, Ramsburg E. Comparison of multiple vaccine vectors in a single heterologous prime-boost trial. Vaccine. 26: 6108-18. PMID 18809447 DOI: 10.1016/J.Vaccine.2008.09.007 |
0.452 |
|
2008 |
Mok H, Tollefson SJ, Podsiad AB, Shepherd BE, Polosukhin VV, Johnston RE, Williams JV, Crowe JE. An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats. Journal of Virology. 82: 11410-8. PMID 18786987 DOI: 10.1128/Jvi.01688-08 |
0.439 |
|
2008 |
Thompson JM, Whitmore AC, Staats HF, Johnston R. The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines. Vaccine. 26: 4998-5003. PMID 18656518 DOI: 10.1016/J.Vaccine.2008.07.011 |
0.456 |
|
2008 |
Thompson JM, Whitmore AC, Staats HF, Johnston RE. Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen. Vaccine. 26: 4267-75. PMID 18582997 DOI: 10.1016/J.Vaccine.2008.05.046 |
0.364 |
|
2008 |
Thompson JM, Nicholson MG, Whitmore AC, Zamora M, West A, Iwasaki A, Staats HF, Johnston RE. Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. Journal of Immunology (Baltimore, Md. : 1950). 181: 574-85. PMID 18566424 DOI: 10.4049/Jimmunol.181.1.574 |
0.404 |
|
2008 |
Fluet ME, Whitmore AC, Moshkoff DA, Fu K, Tang Y, Collier ML, West A, Moore DT, Swanstrom R, Johnston RE, Davis NL. Effects of rapid antigen degradation and VEE glycoprotein specificity on immune responses induced by a VEE replicon vaccine. Virology. 370: 22-32. PMID 17904185 DOI: 10.1016/J.Virol.2007.08.020 |
0.406 |
|
2007 |
Konopka JL, Penalva LO, Thompson JM, White LJ, Beard CW, Keene JD, Johnston RE. A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo. Plos Pathogens. 3: e199. PMID 18215114 DOI: 10.1371/Journal.Ppat.0030199 |
0.409 |
|
2007 |
Mok H, Lee S, Utley TJ, Shepherd BE, Polosukhin VV, Collier ML, Davis NL, Johnston RE, Crowe JE. Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats. Journal of Virology. 81: 13710-22. PMID 17928349 DOI: 10.1128/Jvi.01351-07 |
0.509 |
|
2007 |
Ljungberg K, Whitmore AC, Fluet ME, Moran TP, Shabman RS, Collier ML, Kraus AA, Thompson JM, Montefiori DC, Beard C, Johnston RE. Increased immunogenicity of a DNA-launched Venezuelan equine encephalitis virus-based replicon DNA vaccine. Journal of Virology. 81: 13412-23. PMID 17913817 DOI: 10.1128/Jvi.01799-07 |
0.362 |
|
2007 |
Moran TP, Burgents JE, Long B, Ferrer I, Jaffee EM, Tisch RM, Johnston RE, Serody JS. Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice. Vaccine. 25: 6604-12. PMID 17675184 DOI: 10.1016/J.Vaccine.2007.06.058 |
0.35 |
|
2007 |
Montgomery SA, Johnston RE. Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2. Journal of Virology. 81: 10268-79. PMID 17652399 DOI: 10.1128/Jvi.00371-07 |
0.372 |
|
2007 |
White LJ, Parsons MM, Whitmore AC, Williams BM, de Silva A, Johnston RE. An immunogenic and protective alphavirus replicon particle-based dengue vaccine overcomes maternal antibody interference in weanling mice. Journal of Virology. 81: 10329-39. PMID 17652394 DOI: 10.1128/Jvi.00512-07 |
0.422 |
|
2007 |
Thornburg NJ, Ray CA, Collier ML, Liao HX, Pickup DJ, Johnston RE. Vaccination with Venezuelan equine encephalitis replicons encoding cowpox virus structural proteins protects mice from intranasal cowpox virus challenge. Virology. 362: 441-52. PMID 17292434 DOI: 10.1016/J.Virol.2007.01.001 |
0.467 |
|
2007 |
Cecil C, West A, Collier M, Jurgens C, Madden V, Whitmore A, Johnston R, Moore DT, Swanstrom R, Davis NL. Structure and immunogenicity of alternative forms of the simian immunodeficiency virus gag protein expressed using Venezuelan equine encephalitis virus replicon particles. Virology. 362: 362-73. PMID 17275057 DOI: 10.1016/J.Virol.2006.12.029 |
0.468 |
|
2007 |
MacLachlan NJ, Balasuriya UB, Davis NL, Collier M, Johnston RE, Ferraro GL, Guthrie AJ. Experiences with new generation vaccines against equine viral arteritis, West Nile disease and African horse sickness. Vaccine. 25: 5577-82. PMID 17267078 DOI: 10.1016/J.Vaccine.2006.12.058 |
0.402 |
|
2007 |
Ryman KD, Gardner CL, Meier KC, Biron CA, Johnston RE, Klimstra WB. Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease. The Journal of General Virology. 88: 518-29. PMID 17251570 DOI: 10.1099/Vir.0.82359-0 |
0.499 |
|
2007 |
Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Correction: Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants Plos Medicine. 4: e80. DOI: 10.1371/Journal.Pmed.0040080 |
0.362 |
|
2006 |
Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. Plos Medicine. 3: e525. PMID 17194199 DOI: 10.1371/Journal.Pmed.0030525 |
0.393 |
|
2006 |
Montgomery SA, Berglund P, Beard CW, Johnston RE. Ribosomal protein S6 associates with alphavirus nonstructural protein 2 and mediates expression from alphavirus messages. Journal of Virology. 80: 7729-39. PMID 16840351 DOI: 10.1128/Jvi.00425-06 |
0.37 |
|
2006 |
LoBue AD, Lindesmith L, Yount B, Harrington PR, Thompson JM, Johnston RE, Moe CL, Baric RS. Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains. Vaccine. 24: 5220-34. PMID 16650512 DOI: 10.1016/J.Vaccine.2006.03.080 |
0.455 |
|
2006 |
Thompson JM, Whitmore AC, Konopka JL, Collier ML, Richmond EM, Davis NL, Staats HF, Johnston RE. Mucosal and systemic adjuvant activity of alphavirus replicon particles. Proceedings of the National Academy of Sciences of the United States of America. 103: 3722-7. PMID 16505353 DOI: 10.1073/Pnas.0600287103 |
0.422 |
|
2006 |
Thomas CE, Zhu W, Van Dam CN, Davis NL, Johnston RE, Sparling PF. Vaccination of mice with gonococcal TbpB expressed in vivo from Venezuelan equine encephalitis viral replicon particles. Infection and Immunity. 74: 1612-20. PMID 16495532 DOI: 10.1128/Iai.74.3.1612-1620.2006 |
0.41 |
|
2005 |
Zhu W, Thomas CE, Chen CJ, Van Dam CN, Johnston RE, Davis NL, Sparling PF. Comparison of immune responses to gonococcal PorB delivered as outer membrane vesicles, recombinant protein, or Venezuelan equine encephalitis virus replicon particles. Infection and Immunity. 73: 7558-68. PMID 16239559 DOI: 10.1128/Iai.73.11.7558-7568.2005 |
0.402 |
|
2005 |
Moran TP, Collier M, McKinnon KP, Davis NL, Johnston RE, Serody JS. A novel viral system for generating antigen-specific T cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 3431-8. PMID 16116238 DOI: 10.4049/Jimmunol.175.5.3431 |
0.334 |
|
2005 |
Johnston RE, Johnson PR, Connell MJ, Montefiori DC, West A, Collier ML, Cecil C, Swanstrom R, Frelinger JA, Davis NL. Vaccination of macaques with SIV immunogens delivered by Venezuelan equine encephalitis virus replicon particle vectors followed by a mucosal challenge with SIVsmE660. Vaccine. 23: 4969-79. PMID 16005121 DOI: 10.1016/J.Vaccine.2005.05.034 |
0.478 |
|
2005 |
Lambeth CR, White LJ, Johnston RE, de Silva AM. Flow cytometry-based assay for titrating dengue virus. Journal of Clinical Microbiology. 43: 3267-72. PMID 16000446 DOI: 10.1128/Jcm.43.7.3267-3272.2005 |
0.394 |
|
2004 |
Johnston RE. A candidate vaccine for severe acute respiratory syndrome. The New England Journal of Medicine. 351: 827-8. PMID 15317899 DOI: 10.1056/Nejmcibr041657 |
0.319 |
|
2004 |
Paredes AM, Ferreira D, Horton M, Saad A, Tsuruta H, Johnston R, Klimstra W, Ryman K, Hernandez R, Chiu W, Brown DT. Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion. Virology. 324: 373-86. PMID 15207623 DOI: 10.1016/J.Virol.2004.03.046 |
0.37 |
|
2004 |
Johnston RE, Davis NL. Future vaccines against emerging encephalitides. Archives of Virology. Supplementum. 207-20. PMID 15119776 DOI: 10.1007/978-3-7091-0572-6_19 |
0.358 |
|
2004 |
Ryman KD, Klimstra WB, Johnston RE. Attenuation of Sindbis virus variants incorporating uncleaved PE2 glycoprotein is correlated with attachment to cell-surface heparan sulfate. Virology. 322: 1-12. PMID 15063111 DOI: 10.1016/J.Virol.2004.01.003 |
0.466 |
|
2004 |
Rybarczyk BJ, Montefiori D, Johnson PR, West A, Johnston RE, Swanstrom R. Correlation between env V1/V2 region diversification and neutralizing antibodies during primary infection by simian immunodeficiency virus sm in rhesus macaques. Journal of Virology. 78: 3561-71. PMID 15016879 DOI: 10.1128/Jvi.78.7.3561-3571.2004 |
0.409 |
|
2003 |
Gipson CL, Davis NL, Johnston RE, de Silva AM. Evaluation of Venezuelan Equine Encephalitis (VEE) replicon-based Outer surface protein A (OspA) vaccines in a tick challenge mouse model of Lyme disease. Vaccine. 21: 3875-84. PMID 12922122 DOI: 10.1016/S0264-410X(03)00307-4 |
0.422 |
|
2003 |
Pratt WD, Davis NL, Johnston RE, Smith JF. Genetically engineered, live attenuated vaccines for Venezuelan equine encephalitis: testing in animal models. Vaccine. 21: 3854-62. PMID 12922119 DOI: 10.1016/S0264-410X(03)00328-1 |
0.4 |
|
2003 |
Williamson C, Morris L, Maughan MF, Ping LH, Dryga SA, Thomas R, Reap EA, Cilliers T, van Harmelen J, Pascual A, Ramjee G, Gray G, Johnston R, Karim SA, Swanstrom R. Characterization and selection of HIV-1 subtype C isolates for use in vaccine development. Aids Research and Human Retroviruses. 19: 133-44. PMID 12639249 DOI: 10.1089/088922203762688649 |
0.403 |
|
2003 |
Heise MT, White LJ, Simpson DA, Leonard C, Bernard KA, Meeker RB, Johnston RE. An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis. Journal of Virology. 77: 1149-56. PMID 12502831 DOI: 10.1128/Jvi.77.2.1149-1156.2003 |
0.413 |
|
2002 |
Davis NL, West A, Reap E, MacDonald G, Collier M, Dryga S, Maughan M, Connell M, Walker C, McGrath K, Cecil C, Ping LH, Frelinger J, Olmsted R, Keith P, ... ... Johnston RE, et al. Alphavirus replicon particles as candidate HIV vaccines. Iubmb Life. 53: 209-11. PMID 12120997 DOI: 10.1080/15216540212657 |
0.481 |
|
2002 |
Ryman KD, White LJ, Johnston RE, Klimstra WB. Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis. Viral Immunology. 15: 53-76. PMID 11952147 DOI: 10.1089/088282402317340233 |
0.422 |
|
2002 |
Baric RS, Yount B, Lindesmith L, Harrington PR, Greene SR, Tseng FC, Davis N, Johnston RE, Klapper DG, Moe CL. Expression and self-assembly of norwalk virus capsid protein from venezuelan equine encephalitis virus replicons. Journal of Virology. 76: 3023-30. PMID 11861868 DOI: 10.1128/Jvi.76.6.3023-3030.2002 |
0.436 |
|
2002 |
Balasuriya UB, Heidner HW, Davis NL, Wagner HM, Hullinger PJ, Hedges JF, Williams JC, Johnston RE, David Wilson W, Liu IK, James MacLachlan N. Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses. Vaccine. 20: 1609-17. PMID 11858869 DOI: 10.1016/S0264-410X(01)00485-6 |
0.451 |
|
2002 |
Harrington PR, Yount B, Johnston RE, Davis N, Moe C, Baric RS. Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles. Journal of Virology. 76: 730-42. PMID 11752163 DOI: 10.1128/Jvi.76.2.730-742.2002 |
0.549 |
|
2001 |
Smit JM, Klimstra WB, Ryman KD, Bittman R, Johnston RE, Wilschut J. PE2 cleavage mutants of Sindbis virus: correlation between viral infectivity and pH-dependent membrane fusion activation of the spike heterodimer. Journal of Virology. 75: 11196-204. PMID 11602759 DOI: 10.1128/Jvi.75.22.11196-11204.2001 |
0.461 |
|
2001 |
Charles PC, Trgovcich J, Davis NL, Johnston RE. Immunopathogenesis and immune modulation of Venezuelan equine encephalitis virus-induced disease in the mouse. Virology. 284: 190-202. PMID 11384219 DOI: 10.1006/Viro.2001.0878 |
0.468 |
|
2001 |
White LJ, Wang JG, Davis NL, Johnston RE. Role of alpha/beta interferon in Venezuelan equine encephalitis virus pathogenesis: effect of an attenuating mutation in the 5' untranslated region. Journal of Virology. 75: 3706-18. PMID 11264360 DOI: 10.1128/Jvi.75.8.3706-3718.2001 |
0.42 |
|
2000 |
Schultz-Cherry S, Dybing JK, Davis NL, Williamson C, Suarez DL, Johnston R, Perdue ML. Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin H5N1 viruses. Virology. 278: 55-9. PMID 11112481 DOI: 10.1006/Viro.2000.0635 |
0.477 |
|
2000 |
Bernard KA, Klimstra WB, Johnston RE. Mutations in the E2 glycoprotein of Venezuelan equine encephalitis virus confer heparan sulfate interaction, low morbidity, and rapid clearance from blood of mice. Virology. 276: 93-103. PMID 11021998 DOI: 10.1006/Viro.2000.0546 |
0.474 |
|
2000 |
Heise MT, Simpson DA, Johnston RE. Sindbis-group alphavirus replication in periosteum and endosteum of long bones in adult mice. Journal of Virology. 74: 9294-9. PMID 10982376 DOI: 10.1128/Jvi.74.19.9294-9299.2000 |
0.418 |
|
2000 |
Hart MK, Caswell-Stephan K, Bakken R, Tammariello R, Pratt W, Davis N, Johnston RE, Smith J, Steele K. Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate. Vaccine. 18: 3067-75. PMID 10825611 DOI: 10.1016/S0264-410X(00)00042-6 |
0.42 |
|
2000 |
Aronson JF, Grieder FB, Davis NL, Charles PC, Knott T, Brown K, Johnston RE. A single-site mutant and revertants arising in vivo define early steps in the pathogenesis of Venezuelan equine encephalitis virus. Virology. 270: 111-23. PMID 10772984 DOI: 10.1006/Viro.2000.0241 |
0.627 |
|
2000 |
Heise MT, Simpson DA, Johnston RE. A single amino acid change in nsP1 attenuates neurovirulence of the Sindbis-group alphavirus S.A.AR86. Journal of Virology. 74: 4207-13. PMID 10756033 DOI: 10.1128/Jvi.74.9.4207-4213.2000 |
0.448 |
|
2000 |
Ryman KD, Klimstra WB, Nguyen KB, Biron CA, Johnston RE. Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism. Journal of Virology. 74: 3366-78. PMID 10708454 DOI: 10.1128/Jvi.74.7.3366-3378.2000 |
0.439 |
|
2000 |
Boehme KW, Williams JC, Johnston RE, Heidner HW. Linkage of an alphavirus host-range restriction to the carbohydrate-processing phenotypes of the host cell. The Journal of General Virology. 81: 161-70. PMID 10640554 DOI: 10.1099/0022-1317-81-1-161 |
0.387 |
|
2000 |
MacDonald GH, Johnston RE. Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis. Journal of Virology. 74: 914-22. PMID 10623754 DOI: 10.1128/Jvi.74.2.914-922.2000 |
0.425 |
|
2000 |
Davis NL, Caley IJ, Brown KW, Betts MR, Irlbeck DM, McGrath KM, Connell MJ, Montefiori DC, Frelinger JA, Swanstrom R, Johnson PR, Johnston RE. Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles. Journal of Virology. 74: 371-8. PMID 10590126 DOI: 10.1128/Jvi.74.1.371-378.2000 |
0.48 |
|
2000 |
Davis NL, Caley IJ, Brown KW, Betts MR, Irlbeck DM, McGrath KM, Connell MJ, Montefiori DC, Frelinger JA, Swanstrom R, Johnson PR, Johnston RE. Vaccination of Macaques against Pathogenic Simian Immunodeficiency Virus with Venezuelan Equine Encephalitis Virus Replicon Particles Journal of Virology. 74: 3430-3430. DOI: 10.1128/Jvi.74.7.3430-3430.2000 |
0.485 |
|
1999 |
Klimstra WB, Ryman KD, Bernard KA, Nguyen KB, Biron CA, Johnston RE. Infection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome. Journal of Virology. 73: 10387-98. PMID 10559357 DOI: 10.1128/Jvi.73.12.10387-10398.1999 |
0.488 |
|
1999 |
Trgovcich J, Aronson JF, Eldridge JC, Johnston RE. TNFalpha, interferon, and stress response induction as a function of age-related susceptibility to fatal Sindbis virus infection of mice. Virology. 263: 339-48. PMID 10544107 DOI: 10.1006/Viro.1999.9913 |
0.663 |
|
1999 |
Caley IJ, Betts MR, Davis NL, Swanstrom R, Frelinger JA, Johnston RE. Venezuelan equine encephalitis virus vectors expressing HIV-1 proteins: vector design strategies for improved vaccine efficacy. Vaccine. 17: 3124-35. PMID 10462249 DOI: 10.1016/S0264-410X(99)00142-5 |
0.425 |
|
1999 |
Klimstra WB, Heidner HW, Johnston RE. The furin protease cleavage recognition sequence of Sindbis virus PE2 can mediate virion attachment to cell surface heparan sulfate. Journal of Virology. 73: 6299-306. PMID 10400721 DOI: 10.1128/Jvi.73.8.6299-6306.1999 |
0.433 |
|
1998 |
Klimstra WB, Ryman KD, Johnston RE. Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor. Journal of Virology. 72: 7357-66. PMID 9696832 DOI: 10.1128/Jvi.72.9.7357-7366.1998 |
0.448 |
|
1998 |
Paredes AM, Heidner H, Thuman-Commike P, Prasad BV, Johnston RE, Chiu W. Structural localization of the E3 glycoprotein in attenuated Sindbis virus mutants. Journal of Virology. 72: 1534-41. PMID 9445057 DOI: 10.1128/Jvi.72.2.1534-1541.1998 |
0.428 |
|
1998 |
Paredes AM, Heidner H, Thuman-Commike P, Venkataram Prasad BV, Johnston RE, Chiu W. Structural Localization of the E3 Glycoprotein in Attenuated Sindbis Virus Mutants Journal of Virology. 72: 1534-1541. DOI: 10.1128/jvi.72.2.1534-1541.1998 |
0.322 |
|
1997 |
Pushko P, Parker M, Ludwig GV, Davis NL, Johnston RE, Smith JF. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology. 239: 389-401. PMID 9434729 DOI: 10.1006/Viro.1997.8878 |
0.49 |
|
1997 |
Charles PC, Brown KW, Davis NL, Hart MK, Johnston RE. Mucosal immunity induced by parenteral immunization with a live attenuated Venezuelan equine encephalitis virus vaccine candidate. Virology. 228: 153-60. PMID 9123821 DOI: 10.1006/Viro.1996.8381 |
0.477 |
|
1997 |
Caley IJ, Betts MR, Irlbeck DM, Davis NL, Swanstrom R, Frelinger JA, Johnston RE. Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector. Journal of Virology. 71: 3031-8. PMID 9060663 DOI: 10.1128/Jvi.71.4.3031-3038.1997 |
0.444 |
|
1997 |
Trgovcich J, Ryman K, Extrom P, Eldridge JC, Aronson JF, Johnston RE. Sindbis virus infection of neonatal mice results in a severe stress response. Virology. 227: 234-8. PMID 9007079 DOI: 10.1006/Viro.1996.8289 |
0.679 |
|
1996 |
Trgovcich J, Aronson JF, Johnston RE. Fatal Sindbis virus infection of neonatal mice in the absence of encephalitis. Virology. 224: 73-83. PMID 8862401 DOI: 10.1006/Viro.1996.0508 |
0.685 |
|
1996 |
Simpson DA, Davis NL, Lin SC, Russell D, Johnston RE. Complete nucleotide sequence and full-length cDNA clone of S.A.AR86 a South African alphavirus related to Sindbis. Virology. 222: 464-9. PMID 8806532 DOI: 10.1006/Viro.1996.0445 |
0.32 |
|
1996 |
Davis NL, Brown KW, Johnston RE. A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge. Journal of Virology. 70: 3781-7. PMID 8648713 DOI: 10.1128/Jvi.70.6.3781-3787.1996 |
0.483 |
|
1996 |
Heidner HW, Knott TA, Johnston RE. Differential processing of sindbis virus glycoprotein PE2 in cultured vertebrate and arthropod cells. Journal of Virology. 70: 2069-73. PMID 8627739 DOI: 10.1128/Jvi.70.3.2069-2073.1996 |
0.425 |
|
1996 |
McKnight KL, Simpson DA, Lin SC, Knott TA, Polo JM, Pence DF, Johannsen DB, Heidner HW, Davis NL, Johnston RE. Deduced consensus sequence of Sindbis virus strain AR339: mutations contained in laboratory strains which affect cell culture and in vivo phenotypes. Journal of Virology. 70: 1981-9. PMID 8627724 DOI: 10.1128/Jvi.70.3.1981-1989.1996 |
0.403 |
|
1995 |
Grieder FB, Davis NL, Aronson JF, Charles PC, Sellon DC, Suzuki K, Johnston RE. Specific restrictions in the progression of Venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins. Virology. 206: 994-1006. PMID 7856110 DOI: 10.1006/Viro.1995.1022 |
0.685 |
|
1995 |
Charles PC, Walters E, Margolis F, Johnston RE. Mechanism of neuroinvasion of Venezuelan equine encephalitis virus in the mouse. Virology. 208: 662-71. PMID 7747437 DOI: 10.1006/Viro.1995.1197 |
0.427 |
|
1995 |
Davis NL, Brown KW, Greenwald GF, Zajac AJ, Zacny VL, Smith JF, Johnston RE. Attenuated mutants of Venezuelan equine encephalitis virus containing lethal mutations in the PE2 cleavage signal combined with a second-site suppressor mutation in E1. Virology. 212: 102-10. PMID 7676619 DOI: 10.1006/Viro.1995.1458 |
0.472 |
|
1994 |
Davis NL, Grieder FB, Smith JF, Greenwald GF, Valenski ML, Sellon DC, Charles PC, Johnston RE. A molecular genetic approach to the study of Venezuelan equine encephalitis virus pathogenesis. Archives of Virology. Supplementum. 9: 99-109. PMID 8032286 DOI: 10.1007/978-3-7091-9326-6_11 |
0.487 |
|
1994 |
Heidner HW, Johnston RE. The amino-terminal residue of Sindbis virus glycoprotein E2 influences virus maturation, specific infectivity for BHK cells, and virulence in mice. Journal of Virology. 68: 8064-70. PMID 7966596 DOI: 10.1128/Jvi.68.12.8064-8070.1994 |
0.465 |
|
1994 |
Heidner HW, McKnight KL, Davis NL, Johnston RE. Lethality of PE2 incorporation into Sindbis virus can be suppressed by second-site mutations in E3 and E2. Journal of Virology. 68: 2683-92. PMID 7908062 DOI: 10.1128/Jvi.68.4.2683-2692.1994 |
0.389 |
|
1993 |
Schoepp RJ, Johnston RE. Directed mutagenesis of a Sindbis virus pathogenesis site. Virology. 193: 149-59. PMID 8438562 DOI: 10.1006/Viro.1993.1111 |
0.462 |
|
1993 |
Paredes AM, Brown DT, Rothnagel R, Chiu W, Schoepp RJ, Johnston RE, Prasad BV. Three-dimensional structure of a membrane-containing virus. Proceedings of the National Academy of Sciences of the United States of America. 90: 9095-9. PMID 8415660 DOI: 10.1073/Pnas.90.19.9095 |
0.374 |
|
1993 |
Schoepp RJ, Johnston RE. Sindbis virus pathogenesis: phenotypic reversion of an attenuated strain to virulence by second-site intragenic suppressor mutations. The Journal of General Virology. 74: 1691-5. PMID 8345360 DOI: 10.1099/0022-1317-74-8-1691 |
0.359 |
|
1992 |
Meyer WJ, Gidwitz S, Ayers VK, Schoepp RJ, Johnston RE. Conformational alteration of Sindbis virion glycoproteins induced by heat, reducing agents, or low pH. Journal of Virology. 66: 3504-13. PMID 1374808 DOI: 10.1128/Jvi.66.6.3504-3513.1992 |
0.363 |
|
1991 |
Davis NL, Powell N, Greenwald GF, Willis LV, Johnson BJ, Smith JF, Johnston RE. Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA clone. Virology. 183: 20-31. PMID 2053280 DOI: 10.1016/0042-6822(91)90114-Q |
0.416 |
|
1991 |
Presley JF, Polo JM, Johnston RE, Brown DT. Proteolytic processing of the Sindbis virus membrane protein precursor PE2 is nonessential for growth in vertebrate cells but is required for efficient growth in invertebrate cells. Journal of Virology. 65: 1905-9. PMID 1848310 DOI: 10.1128/Jvi.65.4.1905-1909.1991 |
0.47 |
|
1991 |
Polo JM, Johnston RE. Mutational analysis of a virulence locus in the E2 glycoprotein gene of Sindbis virus. Journal of Virology. 65: 6358-61. PMID 1656101 DOI: 10.1128/JVI.65.11.6358-6361.1991 |
0.404 |
|
1990 |
Polo JM, Johnston RE. Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitro. Journal of Virology. 64: 4438-44. PMID 2384921 DOI: 10.1128/JVI.64.9.4438-4444.1990 |
0.322 |
|
1990 |
Pence DF, Davis NL, Johnston RE. Antigenic and genetic characterization of Sindbis virus monoclonal antibody escape mutants which define a pathogenesis domain on glycoprotein E2. Virology. 175: 41-9. PMID 2309450 DOI: 10.1016/0042-6822(90)90184-S |
0.363 |
|
1989 |
Russell DL, Dalrymple JM, Johnston RE. Sindbis virus mutations which coordinately affect glycoprotein processing, penetration, and virulence in mice. Journal of Virology. 63: 1619-29. PMID 2926866 DOI: 10.1128/JVI.63.4.1619-1629.1989 |
0.337 |
|
1988 |
Flynn DC, Olmsted RA, Mackenzie JM, Johnston RE. Antibody-mediated activation of Sindbis virus. Virology. 166: 82-90. PMID 3413988 DOI: 10.1016/0042-6822(88)90149-3 |
0.312 |
|
1988 |
Johnston RE, Smith JF. Selection for accelerated penetration in cell culture coselects for attenuated mutants of Venezuelan equine encephalitis virus. Virology. 162: 437-43. PMID 3341117 DOI: 10.1016/0042-6822(88)90484-9 |
0.356 |
|
1988 |
Mackie GA, Johnston R, Bancroft JB. Single- and double-stranded viral RNAs in plants infected with the potexviruses papaya mosaic virus and foxtail mosaic virus. Intervirology. 29: 170-7. PMID 3182231 DOI: 10.1159/000150043 |
0.36 |
|
1988 |
Polo JM, Davis NL, Rice CM, Huang HV, Johnston RE. Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro. Journal of Virology. 62: 2124-33. PMID 2835514 DOI: 10.1128/Jvi.62.6.2124-2133.1988 |
0.475 |
|
1988 |
Polo JM, Davis NL, Rice CM, Huang HV, Johnston RE. Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro. Journal of Virology. 62: 2124-2133. DOI: 10.1128/jvi.62.6.2124-2133.1988 |
0.389 |
|
1986 |
Davis NL, Fuller FJ, Dougherty WG, Olmsted RA, Johnston RE. A single nucleotide change in the E2 glycoprotein gene of Sindbis virus affects penetration rate in cell culture and virulence in neonatal mice. Proceedings of the National Academy of Sciences of the United States of America. 83: 6771-5. PMID 3462725 DOI: 10.1073/Pnas.83.18.6771 |
0.404 |
|
1985 |
Dougherty WG, Allison RF, Dawn Parks T, Johnston RE, Feild MJ, Armstrong FB. Nucleotide sequence at the 3' terminus of pepper mottle virus genomic RNA: evidence for an alternative mode of potyvirus capsid protein gene organization. Virology. 146: 282-91. PMID 18640557 DOI: 10.1016/0042-6822(85)90011-X |
0.32 |
|
1984 |
Olmsted RA, Baric RS, Sawyer BA, Johnston RE. Sindbis virus mutants selected for rapid growth in cell culture display attenuated virulence in animals. Science (New York, N.Y.). 225: 424-7. PMID 6204381 DOI: 10.1126/Science.6204381 |
0.351 |
|
1981 |
Baric RS, Trent DW, Johnston RE. A Sindbis virus variant with a cell-determined latent period. Virology. 110: 237-42. PMID 7210508 DOI: 10.1016/0042-6822(81)90029-5 |
0.332 |
|
1978 |
Johnston RE, Faulkner P. Reversible inhibition of Sindbis virus penetration in hypertonic medium. Journal of Virology. 25: 436-8. PMID 621783 DOI: 10.1128/JVI.25.1.436-438.1978 |
0.324 |
|
1974 |
Johnston RE, Wan K, Bose HR. Homologous interference induced by Sindbis virus. Journal of Virology. 14: 1076-82. PMID 4473566 |
0.608 |
|
1972 |
Johnston RE, Bose HR. An adenylate-rich segment in the virion RNA of Sindbis virus. Biochemical and Biophysical Research Communications. 46: 712-8. PMID 5061927 DOI: 10.1016/S0006-291X(72)80198-0 |
0.564 |
|
1972 |
Johnston RE, Bose HR. Correlation of messenger RNA function with adenylate-rich segments in the genomes of single-stranded RNA viruses. Proceedings of the National Academy of Sciences of the United States of America. 69: 1514-6. PMID 4338595 DOI: 10.1073/Pnas.69.6.1514 |
0.594 |
|
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