| Year |
Citation |
Score |
| 2020 |
Lourenço AR, Roukens MG, Seinstra D, Frederiks CL, Pals CE, Vervoort SJ, Margarido AS, van Rheenen J, Coffer PJ. C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition. Nature Communications. 11: 785. PMID 32034145 DOI: 10.1038/S41467-020-14556-X |
0.318 |
|
| 2019 |
Fleskens V, Minutti CM, Wu X, Wei P, Pals CEGM, McCrae J, Hemmers S, Groenewold V, Vos HJ, Rudensky A, Pan F, Li H, Zaiss DM, Coffer PJ. Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells. Cell Reports. 26: 3600-3612.e6. PMID 30917315 DOI: 10.1016/J.Celrep.2019.02.087 |
0.406 |
|
| 2018 |
Vervoort SJ, de Jong OG, Roukens MG, Frederiks CL, Vermeulen JF, Lourenço AR, Bella L, Vidakovic AT, Sandoval JL, Moelans C, van Amersfoort M, Dallman MJ, Bruna A, Caldas C, Nieuwenhuis E, ... ... Coffer PJ, et al. Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis. Elife. 7. PMID 30507376 DOI: 10.7554/Elife.27706 |
0.344 |
|
| 2018 |
Braccioli L, Vervoort SJ, Puma G, Nijboer CH, Coffer PJ. SOX4 inhibits oligodendrocyte differentiation of embryonic neural stem cells in vitro by inducing Hes5 expression. Stem Cell Research. 33: 110-119. PMID 30343100 DOI: 10.1016/J.Scr.2018.10.005 |
0.371 |
|
| 2018 |
van Loosdregt J, Coffer PJ. The Role of WNT Signaling in Mature T Cells: T Cell Factor Is Coming Home. Journal of Immunology (Baltimore, Md. : 1950). 201: 2193-2200. PMID 30301837 DOI: 10.4049/Jimmunol.1800633 |
0.367 |
|
| 2018 |
Petrelli A, Mijnheer G, Hoytema van Konijnenburg DP, van der Wal MM, Giovannone B, Mocholi E, Vazirpanah N, Broen JC, Hijnen D, Oldenburg B, Coffer PJ, Vastert SJ, Prakken BJ, Spierings E, Pandit A, et al. PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation. The Journal of Clinical Investigation. 128: 4669-4681. PMID 30198907 DOI: 10.1172/Jci96107 |
0.339 |
|
| 2018 |
Ribeiro D, Melão A, van Boxtel R, Santos CI, Silva A, Silva MC, Cardoso BA, Coffer PJ, Barata JT. STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells. Blood Advances. 2: 2199-2213. PMID 30185437 DOI: 10.1182/Bloodadvances.2018021063 |
0.387 |
|
| 2018 |
Zaiss DMW, Coffer PJ. Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis. Nature Reviews. Immunology. 18: 703-715. PMID 30177790 DOI: 10.1038/S41577-018-0048-9 |
0.369 |
|
| 2018 |
Vervoort SJ, Lourenço AR, Tufegdzic Vidakovic A, Mocholi E, Sandoval JL, Rueda OM, Frederiks C, Pals C, Peeters JGC, Caldas C, Bruna A, Coffer PJ. SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis. Nucleic Acids Research. 46: 9578-9590. PMID 30137431 DOI: 10.1093/Nar/Gky755 |
0.329 |
|
| 2018 |
Mocholi E, Dowling SD, Botbol Y, Gruber RC, Ray AK, Vastert S, Shafit-Zagardo B, Coffer PJ, Macian F. Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy. Cell Reports. 24: 1136-1150. PMID 30067971 DOI: 10.1016/J.Celrep.2018.06.065 |
0.406 |
|
| 2018 |
Bartels M, Govers A, Polak R, Vervoort S, van Boxtel R, Pals C, Bierings M, van Solinge W, Egberts T, Nieuwenhuis E, Mokry M, Coffer PJ. Megakaryocyte lineage development is controlled by modulation of protein acetylation. Plos One. 13: e0196400. PMID 29698469 DOI: 10.1371/Journal.Pone.0196400 |
0.364 |
|
| 2018 |
Vonk LA, van Dooremalen SFJ, Liv N, Klumperman J, Coffer PJ, Saris DBF, Lorenowicz MJ. Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration. Theranostics. 8: 906-920. PMID 29463990 DOI: 10.7150/Thno.20746 |
0.34 |
|
| 2018 |
Daniel R, Melão A, Boxtel Rv, Santos C, Silva A, Silva MC, Cardoso BA, Coffer PJ, Barata J. IL-7 Activates a STAT5/PIM1 Axis to Promote T-Cell Acute Lymphoblastic Leukemia Proliferation and Viability in a Bcl-2-Independent Manner Blood. 132: 914-914. DOI: 10.1182/Blood-2018-99-113778 |
0.353 |
|
| 2017 |
Braccioli L, Vervoort SJ, Adolfs Y, Heijnen CJ, Basak O, Pasterkamp RJ, Nijboer CH, Coffer PJ. FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression. Stem Cell Reports. 9: 1530-1545. PMID 29141232 DOI: 10.1016/J.Stemcr.2017.10.012 |
0.385 |
|
| 2017 |
Minutti CM, Drube S, Blair N, Schwartz C, McCrae JC, McKenzie AN, Kamradt T, Mokry M, Coffer PJ, Sibilia M, Sijts AJ, Fallon PG, Maizels RM, Zaiss DM. Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion. Immunity. 47: 710-722.e6. PMID 29045902 DOI: 10.1016/J.Immuni.2017.09.013 |
0.364 |
|
| 2017 |
Lourenço AR, Coffer PJ. SOX4: Joining the Master Regulators of Epithelial-to-Mesenchymal Transition? Trends in Cancer. 3: 571-582. PMID 28780934 DOI: 10.1016/J.Trecan.2017.06.002 |
0.363 |
|
| 2017 |
Folkerts H, Hilgendorf S, Wierenga ATJ, Jaques J, Mulder AB, Coffer PJ, Schuringa JJ, Vellenga E. Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia. Cell Death & Disease. 8: e2927. PMID 28703806 DOI: 10.1038/Cddis.2017.317 |
0.388 |
|
| 2016 |
Gomez-Puerto MC, Folkerts H, Wierenga AT, Schepers K, Schuringa JJ, Coffer PJ, Vellenga E. Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34(+) Hematopoietic Stem-Progenitor Cells. Stem Cells (Dayton, Ohio). 34: 1651-63. PMID 26930546 DOI: 10.1002/Stem.2347 |
0.716 |
|
| 2016 |
Folkerts H, Hilgendorf S, Wierenga AT, Coffer PJ, Schuringa JJ, Vellenga E. Blocking the Autophagy Pathway As Potential Target for the Treatment of Wild Type P53 AMLs Blood. 128: 770-770. DOI: 10.1182/Blood.V128.22.770.770 |
0.4 |
|
| 2015 |
Steins A, Dik P, Müller WH, Vervoort SJ, Reimers K, Kuhbier JW, Vogt PM, van Apeldoorn AA, Coffer PJ, Schepers K. In Vitro Evaluation of Spider Silk Meshes as a Potential Biomaterial for Bladder Reconstruction. Plos One. 10: e0145240. PMID 26689371 DOI: 10.1371/Journal.Pone.0145240 |
0.684 |
|
| 2015 |
Fleskens V, Mokry M, van der Leun AM, Huppelschoten S, Pals CE, Peeters J, Coenen S, Cardoso BA, Barata JT, van Loosdregt J, Coffer PJ. FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2. Oncogene. PMID 26686090 DOI: 10.1038/Onc.2015.481 |
0.388 |
|
| 2015 |
Peeters JG, Vervoort SJ, Tan SC, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Creyghton MP, Coffer PJ, Mokry M, van Loosdregt J. Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression. Cell Reports. PMID 26387944 DOI: 10.1016/J.Celrep.2015.08.046 |
0.352 |
|
| 2015 |
Lozano T, Villanueva L, Durántez M, Gorraiz M, Ruiz M, Belsúe V, Riezu-Boj JI, Hervás-Stubbs S, Oyarzábal J, Bandukwala H, Lourenço AR, Coffer PJ, Sarobe P, Prieto J, Casares N, et al. Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation. Journal of Immunology (Baltimore, Md. : 1950). 195: 3180-9. PMID 26324768 DOI: 10.4049/Jimmunol.1402997 |
0.379 |
|
| 2015 |
Keimpema Mv, Grüneberg LJ, Mokry M, Boxtel Rv, Zelm MCv, Coffer P, Pals ST, Spaargaren M. The forkhead transcription factor FOXP1 represses human plasma cell differentiation Blood. 126: 2098-2109. PMID 26289642 DOI: 10.1182/Blood-2015-02-626176 |
0.39 |
|
| 2015 |
Bartels M, Govers AM, Fleskens V, Lourenço AR, Pals CE, Vervoort SJ, van Gent R, Brenkman AB, Bierings MB, Ackerman SJ, van Loosdregt J, Coffer PJ. Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation. Blood. 125: 1782-92. PMID 25568349 DOI: 10.1182/Blood-2013-12-543850 |
0.325 |
|
| 2015 |
Folkerts H, Wierenga BATJ, Coffer PJ, Schuringa JJ, Vellenga E. Targeting Autophagy As a Potential Therapeutic Strategy for the Treatment of AML Blood. 126: 3831-3831. DOI: 10.1182/Blood.V126.23.3831.3831 |
0.408 |
|
| 2014 |
van Keimpema M, Grüneberg LJ, Mokry M, van Boxtel R, Koster J, Coffer PJ, Pals ST, Spaargaren M. FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells. Blood. 124: 3431-40. PMID 25267198 DOI: 10.1182/Blood-2014-01-553412 |
0.39 |
|
| 2014 |
van Loosdregt J, Coffer PJ. Post-translational modification networks regulating FOXP3 function. Trends in Immunology. 35: 368-78. PMID 25047417 DOI: 10.1016/J.It.2014.06.005 |
0.381 |
|
| 2014 |
Bartels M, Calgarotto AK, Martens AC, Maso V, da Silva SL, Bierings MB, de Souza Queiroz ML, Coffer PJ. Differential effects of nitrostyrene derivatives on myelopoiesis involve regulation of C/EBPα and p38MAPK activity. Plos One. 9: e90586. PMID 24614182 DOI: 10.1371/Journal.Pone.0090586 |
0.372 |
|
| 2014 |
Prins HJ, Braat AK, Gawlitta D, Dhert WJA, Egan DA, Tijssen-Slump E, Yuan H, Coffer PJ, Rozemuller H, Martens AC. In vitro induction of alkaline phosphatase levels predicts in vivo bone forming capacity of human bone marrow stromal cells Stem Cell Research. 12: 428-440. PMID 24384458 DOI: 10.1016/J.Scr.2013.12.001 |
0.302 |
|
| 2014 |
van der Burgh R, Nijhuis L, Pervolaraki K, Compeer EB, Jongeneel LH, van Gijn M, Coffer PJ, Murphy MP, Mastroberardino PG, Frenkel J, Boes M. Defects in mitochondrial clearance predispose human monocytes to interleukin-1β hypersecretion. The Journal of Biological Chemistry. 289: 5000-12. PMID 24356959 DOI: 10.1074/Jbc.M113.536920 |
0.313 |
|
| 2014 |
Folkerts H, Gomez Puerto MC, Wierenga AT, Schepers K, Schuringa JJ, Coffer PJ, Vellenga E. ATG5 and ATG7 Fulfill Essential and Non-Redundant Roles in Human Hematopoietic Stem/Progenitor Cells Blood. 124: 4316-4316. DOI: 10.1182/Blood.V124.21.4316.4316 |
0.711 |
|
| 2014 |
Steins A, Dik P, Van Apeldoorn A, Reimers K, Coffer P, Schepers K. 180 Primary human urothelial cell culture on a matrix of spider silk: A novel technique in bladder reconstruction European Urology Supplements. 13: e180. DOI: 10.1016/S1569-9056(14)60179-2 |
0.692 |
|
| 2014 |
Steins A, Dik P, van Apeldoorn A, Reimers K, Klijn A, de Jong T, Coffer P, Schepers K. MP9-20 PRIMARY HUMAN UROTHELIAL CELL CULTURE ON A MATRIX OF SPIDER SILK; A NOVEL TECHNIQUE IN BLADDER RECONSTRUCTION Journal of Urology. 191. DOI: 10.1016/j.juro.2014.02.508 |
0.634 |
|
| 2013 |
Arpaia N, Campbell C, Fan X, Dikiy S, van der Veeken J, deRoos P, Liu H, Cross JR, Pfeffer K, Coffer PJ, Rudensky AY. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature. 504: 451-5. PMID 24226773 DOI: 10.1038/Nature12726 |
0.353 |
|
| 2013 |
Gao Y, Koppen A, Rakhshandehroo M, Tasdelen I, van de Graaf SF, van Loosdregt J, van Beekum O, Hamers N, van Leenen D, Berkers CR, Berger R, Holstege FC, Coffer PJ, Brenkman AB, Ovaa H, et al. Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60. Nature Communications. 4: 2656. PMID 24141283 DOI: 10.1038/Ncomms3656 |
0.406 |
|
| 2013 |
van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, ... ... Coffer PJ, et al. Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity. 39: 259-71. PMID 23973222 DOI: 10.1016/J.Immuni.2013.05.018 |
0.446 |
|
| 2013 |
van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, ... ... Coffer PJ, et al. Canonical Wnt signaling negatively modulates regulatory T cell function. Immunity. 39: 298-310. PMID 23954131 DOI: 10.1016/J.Immuni.2013.07.019 |
0.418 |
|
| 2013 |
van Boxtel R, Gomez-Puerto C, Mokry M, Eijkelenboom A, van der Vos KE, Nieuwenhuis EE, Burgering BM, Lam EW, Coffer PJ. FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis. Cell Death and Differentiation. 20: 1219-29. PMID 23832113 DOI: 10.1038/cdd.2013.81 |
0.356 |
|
| 2013 |
Steevels TA, van Avondt K, Westerlaken GH, Stalpers F, Walk J, Bont L, Coffer PJ, Meyaard L. Signal inhibitory receptor on leukocytes-1 (SIRL-1) negatively regulates the oxidative burst in human phagocytes. European Journal of Immunology. 43: 1297-308. PMID 23436183 DOI: 10.1002/Eji.201242916 |
0.367 |
|
| 2013 |
Zaiss DM, van Loosdregt J, Gorlani A, Bekker CP, Gröne A, Sibilia M, van Bergen en Henegouwen PM, Roovers RC, Coffer PJ, Sijts AJ. Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor. Immunity. 38: 275-84. PMID 23333074 DOI: 10.1016/J.Immuni.2012.09.023 |
0.375 |
|
| 2013 |
Tasdelen I, van Beekum O, Gorbenko O, Fleskens V, van den Broek NJ, Koppen A, Hamers N, Berger R, Coffer PJ, Brenkman AB, Kalkhoven E. The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity. The Biochemical Journal. 451: 45-53. PMID 23320500 DOI: 10.1042/Bj20121113 |
0.408 |
|
| 2013 |
Vervoort SJ, Lourenço AR, van Boxtel R, Coffer PJ. SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition. Plos One. 8: e53238. PMID 23301048 DOI: 10.1371/Journal.Pone.0053238 |
0.383 |
|
| 2013 |
Vervoort SJ, Boxtel Rv, Coffer PJ. The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe? Oncogene. 32: 3397-3409. PMID 23246969 DOI: 10.1038/Onc.2012.506 |
0.363 |
|
| 2013 |
Braat K, de Jong R, Verhagen L, Gawlitta D, Coffer P, Martens A, Schepers K. The hunt for a replenishable MSC source to create (genetically manipulatable) ectopic human hematopoietic bone marrow niches Experimental Hematology. 41: S66. DOI: 10.1016/J.Exphem.2013.05.259 |
0.636 |
|
| 2012 |
van de Laar L, van den Bosch A, Boonstra A, Binda RS, Buitenhuis M, Janssen HL, Coffer PJ, Woltman AM. PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function. Blood. 120: 4982-91. PMID 23091295 DOI: 10.1182/Blood-2012-02-413229 |
0.419 |
|
| 2012 |
van der Vos KE, Coffer PJ. Glutamine metabolism links growth factor signaling to the regulation of autophagy. Autophagy. 8: 1862-4. PMID 22996802 DOI: 10.4161/Auto.22152 |
0.391 |
|
| 2012 |
van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen LP, Groot Koerkamp MJ, Braat AK, Dansen TB, Holstege FC, ... ... Coffer PJ, et al. Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. Nature Cell Biology. 14: 829-37. PMID 22820375 DOI: 10.1038/Ncb2536 |
0.349 |
|
| 2012 |
van de Laar L, Coffer PJ, Woltman AM. Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy. Blood. 119: 3383-93. PMID 22323450 DOI: 10.1182/Blood-2011-11-370130 |
0.373 |
|
| 2012 |
Vercoulen Y, Guichelaar T, Meerding J, Emmelot M, Pingen M, Storm G, Coffer P, Sawitzki B, Martens A, Mutis T, Prakken B. Application of cultured human regulatory T cells requires preclinical in vivo evaluation The Journal of Allergy and Clinical Immunology. 129: 852-855. PMID 22168999 DOI: 10.1016/J.Jaci.2011.10.037 |
0.325 |
|
| 2011 |
Wehrens EJ, Mijnheer G, Duurland CL, Klein M, Meerding J, van Loosdregt J, de Jager W, Sawitzki B, Coffer PJ, Vastert B, Prakken BJ, van Wijk F. Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells. Blood. 118: 3538-48. PMID 21828127 DOI: 10.1182/Blood-2010-12-328187 |
0.405 |
|
| 2011 |
van de Laar L, van den Bosch A, Wierenga AT, Janssen HL, Coffer PJ, Woltman AM. Tight control of STAT5 activity determines human CD34-derived interstitial dendritic cell and langerhans cell development. Journal of Immunology (Baltimore, Md. : 1950). 186: 7016-24. PMID 21602494 DOI: 10.4049/Jimmunol.1003977 |
0.396 |
|
| 2011 |
van Loosdregt J, Brunen D, Fleskens V, Pals CE, Lam EW, Coffer PJ. Rapid temporal control of Foxp3 protein degradation by sirtuin-1. Plos One. 6: e19047. PMID 21533107 DOI: 10.1371/Journal.Pone.0019047 |
0.4 |
|
| 2011 |
van der Vos KE, Coffer PJ. The extending network of FOXO transcriptional target genes. Antioxidants & Redox Signaling. 14: 579-92. PMID 20673124 DOI: 10.1089/Ars.2010.3419 |
0.36 |
|
| 2011 |
Bartels M, Pals CE, Loosdregt Jv, Ackerman SJ, Bierings M, Coffer PJ. Acetylation of C/EBPε Is Functionally Important During Neutrophil Development Blood. 118: 215-215. DOI: 10.1182/Blood.V118.21.215.215 |
0.337 |
|
| 2011 |
Vercoulen Y, Guichelaar T, Meerding J, Emmelot M, Pingen M, Jager Wd, Mutis T, Martens A, Coffer P, Prakken B. Human induced CD4 + CD25 + FOXP3 + regulatory T cells are suppressive in vitro, but fail to suppress inflammation in vivo Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.148981.27 |
0.383 |
|
| 2010 |
van de Laar L, van den Bosch A, van der Kooij SW, Janssen HL, Coffer PJ, van Kooten C, Woltman AM. A nonredundant role for canonical NF-κB in human myeloid dendritic cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 185: 7252-61. PMID 21076069 DOI: 10.4049/Jimmunol.1000672 |
0.373 |
|
| 2010 |
Buitenhuis M, van der Linden E, Ulfman LH, Hofhuis FM, Bierings MB, Coffer PJ. Protein kinase B (PKB/c-akt) regulates homing of hematopoietic progenitors through modulation of their adhesive and migratory properties. Blood. 116: 2373-84. PMID 20566894 DOI: 10.1182/Blood-2009-10-250258 |
0.426 |
|
| 2010 |
van de Laar L, Buitenhuis M, Wensveen FM, Janssen HL, Coffer PJ, Woltman AM. Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 6600-11. PMID 20488790 DOI: 10.4049/Jimmunol.0903089 |
0.437 |
|
| 2010 |
Bakema JE, Hiemstra IH, Bakker J, de Haij S, Kok Y, Adema G, van Egmond M, Coffer PJ, van de Winkel JG, Leusen JH. c-Jun activating binding protein 1 binds to the IgA receptor and modulates protein levels of FcalphaRI and FcRgamma-chain. European Journal of Immunology. 40: 2035-40. PMID 20411563 DOI: 10.1002/Eji.200939985 |
0.353 |
|
| 2010 |
Steevels TA, Lebbink RJ, Westerlaken GH, Coffer PJ, Meyaard L. Signal inhibitory receptor on leukocytes-1 is a novel functional inhibitory immune receptor expressed on human phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 184: 4741-8. PMID 20375307 DOI: 10.4049/Jimmunol.0902039 |
0.359 |
|
| 2010 |
van Loosdregt J, Vercoulen Y, Guichelaar T, Gent YY, Beekman JM, van Beekum O, Brenkman AB, Hijnen DJ, Mutis T, Kalkhoven E, Prakken BJ, Coffer PJ. Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization. Blood. 115: 965-74. PMID 19996091 DOI: 10.1182/Blood-2009-02-207118 |
0.4 |
|
| 2009 |
de Jager W, Vastert SJ, Beekman JM, Wulffraat NM, Kuis W, Coffer PJ, Prakken BJ. Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis. Arthritis and Rheumatism. 60: 2782-93. PMID 19714583 DOI: 10.1002/Art.24750 |
0.302 |
|
| 2009 |
Geest CR, Buitenhuis M, Groot Koerkamp MJ, Holstege FC, Vellenga E, Coffer PJ. Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors. Blood. 114: 3402-12. PMID 19667405 DOI: 10.1182/Blood-2008-08-175141 |
0.483 |
|
| 2009 |
Beekman JM, Verhagen LP, Geijsen N, Coffer PJ. Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output. Blood. 114: 3917-27. PMID 19654410 DOI: 10.1182/Blood-2009-03-208850 |
0.321 |
|
| 2009 |
Geest CR, Buitenhuis M, Vellenga E, Coffer PJ. Ectopic expression of C/EBPalpha and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasia. Haematologica. 94: 1075-84. PMID 19644139 DOI: 10.3324/Haematol.2008.000471 |
0.375 |
|
| 2009 |
Geest CR, Buitenhuis M, Laarhoven AG, Bierings MB, Bruin MC, Vellenga E, Coffer PJ. p38 MAP kinase inhibits neutrophil development through phosphorylation of C/EBPalpha on serine 21. Stem Cells (Dayton, Ohio). 27: 2271-82. PMID 19544470 DOI: 10.1002/Stem.152 |
0.461 |
|
| 2009 |
Geest CR, Zwartkruis FJ, Vellenga E, Coffer PJ, Buitenhuis M. Mammalian target of rapamycin activity is required for expansion of CD34+ hematopoietic progenitor cells. Haematologica. 94: 901-10. PMID 19535348 DOI: 10.3324/Haematol.13766 |
0.399 |
|
| 2009 |
Geest CR, Coffer PJ. MAPK signaling pathways in the regulation of hematopoiesis. Journal of Leukocyte Biology. 86: 237-50. PMID 19498045 DOI: 10.1189/Jlb.0209097 |
0.436 |
|
| 2009 |
Essaghir A, Dif N, Marbehant CY, Coffer PJ, Demoulin JB. The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors. The Journal of Biological Chemistry. 284: 10334-42. PMID 19244250 DOI: 10.1074/Jbc.M808848200 |
0.359 |
|
| 2008 |
Kuijk LM, Beekman JM, Koster J, Waterham HR, Frenkel J, Coffer PJ. HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation. Blood. 112: 3563-73. PMID 18684863 DOI: 10.1182/Blood-2008-03-144667 |
0.32 |
|
| 2008 |
Fuhler GM, Drayer AL, Olthof SG, Schuringa JJ, Coffer PJ, Vellenga E. Reduced activation of protein kinase B, Rac, and F-actin polymerization contributes to an impairment of stromal cell derived factor-1 induced migration of CD34+ cells from patients with myelodysplasia. Blood. 111: 359-68. PMID 17898317 DOI: 10.1182/Blood-2006-11-060632 |
0.445 |
|
| 2008 |
Buitenhuis M, Verhagen LP, van Deutekom HW, Castor A, Verploegen S, Koenderman L, Jacobsen SE, Coffer PJ. Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis. Blood. 111: 112-21. PMID 17890457 DOI: 10.1182/Blood-2006-07-037572 |
0.466 |
|
| 2008 |
Kuijk L, Frenkel J, Waterham H, Koster J, Coffer P. 12.2 Mevalonate kinase deficiency: Impaired isoprenoid synthesis induces IL-1beta production via activation of Rac1 Pediatric Rheumatology. 6: 1-1. DOI: 10.1186/1546-0096-6-S1-S24 |
0.372 |
|
| 2008 |
Buitenhuis M, Geest CR, Laarhoven AG, Bruin MCA, Bierings MB, Vellenga E, Coffer PJ. p38MAPK Inhibits Neutrophil Development through Phosphorylation of C/EBP alpha on Serine 21 Blood. 112: 328-328. DOI: 10.1182/Blood.V112.11.888.888 |
0.46 |
|
| 2008 |
Bartels M, Geest C, Buitenhuis M, Bierings M, Coffer PJ. Differential Effects of HDAC Inhibitors on CD34+ Hematopoietic Progenitor Lineage Choice Decisions Blood. 112: 4778-4778. DOI: 10.1182/Blood.V112.11.4778.4778 |
0.399 |
|
| 2007 |
Buitenhuis M, Verhagen LP, Cools J, Coffer PJ. Molecular mechanisms underlying FIP1L1-PDGFRA-mediated myeloproliferation. Cancer Research. 67: 3759-66. PMID 17440089 DOI: 10.1158/0008-5472.CAN-06-4183 |
0.376 |
|
| 2007 |
Coffer PJ, Burgering BM. Stressed marrow: FoxOs stem tumour growth. Nature Cell Biology. 9: 251-3. PMID 17330117 DOI: 10.1038/Ncb0307-251 |
0.335 |
|
| 2007 |
Birkenkamp KU, Essafi A, van der Vos KE, da Costa M, Hui RC, Holstege F, Koenderman L, Lam EW, Coffer PJ. FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1. The Journal of Biological Chemistry. 282: 2211-20. PMID 17132628 DOI: 10.1074/Jbc.M606669200 |
0.441 |
|
| 2007 |
Fuhler GM, Blom NR, Coffer PJ, Drayer AL, Vellenga E. The reduced GM-CSF priming of ROS production in granulocytes from patients with myelodysplasia is associated with an impaired lipid raft formation. Journal of Leukocyte Biology. 81: 449-57. PMID 17079651 DOI: 10.1189/Jlb.0506311 |
0.339 |
|
| 2006 |
Van Gorp AGM, Pomeranz KM, Birkenkamp KU, Hui RCY, Lam EWF, Coffer PJ. Chronic Protein Kinase B (PKB/c-akt) activation leads to apoptosis induced by oxidative stress-mediated Foxo3a transcriptional up-regulation Cancer Research. 66: 10760-10769. PMID 17108112 DOI: 10.1158/0008-5472.Can-06-1111 |
0.421 |
|
| 2006 |
Rosas M, Dijkers PF, Lindemans CL, Lammers JW, Koenderman L, Coffer PJ. IL-5-mediated eosinophil survival requires inhibition of GSK-3 and correlates with beta-catenin relocalization. Journal of Leukocyte Biology. 80: 186-95. PMID 16684889 DOI: 10.1189/Jlb.1105636 |
0.37 |
|
| 2006 |
Lindemans CA, Coffer PJ, Schellens IM, de Graaff PM, Kimpen JL, Koenderman L. Respiratory syncytial virus inhibits granulocyte apoptosis through a phosphatidylinositol 3-kinase and NF-kappaB-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 176: 5529-37. PMID 16622022 DOI: 10.4049/Jimmunol.176.9.5529 |
0.358 |
|
| 2006 |
Verbrugge A, de Ruiter T, Geest C, Coffer PJ, Meyaard L. Differential expression of leukocyte-associated Ig-like receptor-1 during neutrophil differentiation and activation. Journal of Leukocyte Biology. 79: 828-36. PMID 16461736 DOI: 10.1189/Jlb.0705370 |
0.419 |
|
| 2006 |
Geest C, Buitenhuis M, Vellenga E, Coffer PJ. p38 and ERK MAPKs Differentially Regulate Expansion and Differentiation of Human Cord Blood Derived CD34+ Cells during Neutropoiesis. Blood. 108: 1130-1130. DOI: 10.1182/Blood.V108.11.1130.1130 |
0.49 |
|
| 2005 |
Real PJ, Benito A, Cuevas J, Berciano MT, Juan Ad, Coffer P, Gomez-Roman J, Lafarga M, Lopez-Vega JM, Fernandez-Luna JL. Blockade of Epidermal Growth Factor Receptors Chemosensitizes Breast Cancer Cells through Up-Regulation of Bnip3L Cancer Research. 65: 8151-8157. PMID 16166289 DOI: 10.1158/0008-5472.Can-05-1134 |
0.318 |
|
| 2005 |
Verploegen S, Ulfman L, van Deutekom HW, van Aalst C, Honing H, Lammers JW, Koenderman L, Coffer PJ. Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function. Blood. 106: 1076-83. PMID 15840691 DOI: 10.1182/Blood-2004-09-3755 |
0.405 |
|
| 2005 |
Buitenhuis M, van Deutekom HW, Verhagen LP, Castor A, Jacobsen SE, Lammers JW, Koenderman L, Coffer PJ. Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2. Blood. 105: 4272-81. PMID 15701714 DOI: 10.1182/Blood-2004-12-4883 |
0.411 |
|
| 2005 |
Liu JW, Chandra D, Rudd MD, Butler AP, Pallotta V, Brown D, Coffer PJ, Tang DG. Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. Oncogene. 24: 2020-31. PMID 15674333 DOI: 10.1038/Sj.Onc.1208385 |
0.327 |
|
| 2005 |
Rosas M, Birkenkamp KU, Lammers JW, Koenderman L, Coffer PJ. Cytokine mediated suppression of TF-1 apoptosis requires PI3K activation and inhibition of Bim expression. Febs Letters. 579: 191-8. PMID 15620712 DOI: 10.1016/J.Febslet.2004.11.074 |
0.438 |
|
| 2005 |
Fuhler G, Drayer A, Coffer P, Vellenga E. Involvement of lipid rafts in impaired fMLP-stimulated ROS production of GM-CSF-primed neutrophils from patients with myelodysplasia. Blood. 106: 3863-3863. DOI: 10.1182/Blood.V106.11.3863.3863 |
0.335 |
|
| 2004 |
Fernández de Mattos S, Essafi A, Soeiro I, Pietersen AM, Birkenkamp KU, Edwards CS, Martino A, Nelson BH, Francis JM, Jones MC, Brosens JJ, Coffer PJ, Lam EW. FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism. Molecular and Cellular Biology. 24: 10058-71. PMID 15509806 DOI: 10.1128/Mcb.24.22.10058-10071.2004 |
0.369 |
|
| 2004 |
Buitenhuis M, Coffer PJ, Koenderman L. Signal transducer and activator of transcription 5 (STAT5). The International Journal of Biochemistry & Cell Biology. 36: 2120-4. PMID 15313458 DOI: 10.1016/J.Biocel.2003.11.008 |
0.407 |
|
| 2004 |
Rosas M, Uings IJ, van Aalst C, Lammers JW, Koenderman L, Coffer PJ. Functional analysis of the interleukin-5 receptor antagonist peptide, AF18748. Cytokine. 26: 247-54. PMID 15183842 DOI: 10.1016/J.Cyto.2003.10.012 |
0.309 |
|
| 2004 |
Bakker WJ, Blázquez-Domingo M, Kolbus A, Besooyen J, Steinlein P, Beug H, Coffer PJ, Löwenberg B, von Lindern M, van Dijk TB. FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. The Journal of Cell Biology. 164: 175-84. PMID 14734530 DOI: 10.1083/Jcb.200307056 |
0.437 |
|
| 2003 |
Sunters A, Fernández de Mattos S, Stahl M, Brosens JJ, Zoumpoulidou G, Saunders CA, Coffer PJ, Medema RH, Coombes RC, Lam EW. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. The Journal of Biological Chemistry. 278: 49795-805. PMID 14527951 DOI: 10.1074/Jbc.M309523200 |
0.37 |
|
| 2003 |
Coffer P. OutFOXing the grim reaper: novel mechanisms regulating longevity by forkhead transcription factors. Science Signaling. 2003. PMID 14506287 DOI: 10.1126/Stke.2003.201.Pe39 |
0.318 |
|
| 2003 |
Coffer PJ. Transcriptional regulation of lymphocyte quiescence: as cunning as a FOX. Trends in Immunology. 24: 470-1; author reply . PMID 12967666 DOI: 10.1016/S1471-4906(03)00205-9 |
0.328 |
|
| 2003 |
Gilley J, Coffer PJ, Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. The Journal of Cell Biology. 162: 613-22. PMID 12913110 DOI: 10.1083/Jcb.200303026 |
0.328 |
|
| 2003 |
Birkenkamp KU, Coffer PJ. FOXO transcription factors as regulators of immune homeostasis: molecules to die for? Journal of Immunology (Baltimore, Md. : 1950). 171: 1623-9. PMID 12902457 DOI: 10.4049/Jimmunol.171.4.1623 |
0.423 |
|
| 2003 |
Buitenhuis M, Baltus B, Lammers JW, Coffer PJ, Koenderman L. Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells. Blood. 101: 134-42. PMID 12393707 DOI: 10.1182/Blood-2002-03-0740 |
0.472 |
|
| 2003 |
Woltman AM, van der Kooij SW, Coffer PJ, Offringa R, Daha MR, van Kooten C. Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood. 101: 1439-45. PMID 12393532 DOI: 10.1182/Blood-2002-06-1688 |
0.409 |
|
| 2002 |
Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature. 419: 316-21. PMID 12239572 DOI: 10.1038/Nature01036 |
0.389 |
|
| 2002 |
Verploegen S, Leeuwen CMv, Deutekom HWMv, Lammers JJ, Koenderman L, Coffer PJ. Role of Ca2+/calmodulin regulated signaling pathways in chemoattractant induced neutrophil effector functions Febs Journal. 269: 4625-4634. PMID 12230575 DOI: 10.1046/J.1432-1033.2002.03162.X |
0.363 |
|
| 2002 |
Stahl M, Dijkers PF, Kops GJ, Lens SM, Coffer PJ, Burgering BM, Medema RH. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. Journal of Immunology (Baltimore, Md. : 1950). 168: 5024-31. PMID 11994454 DOI: 10.4049/Jimmunol.168.10.5024 |
0.411 |
|
| 2002 |
Kops GJ, Medema RH, Glassford J, Essers MA, Dijkers PF, Coffer PJ, Lam EW, Burgering BM. Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Molecular and Cellular Biology. 22: 2025-36. PMID 11884591 DOI: 10.1128/Mcb.22.7.2025-2036.2002 |
0.448 |
|
| 2002 |
Dijkers PF, Birkenkamp KU, Lam EW-, Thomas NSB, Lammers JJ, Koenderman L, Coffer PJ. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B–enhanced cell survival through maintenance of mitochondrial integrity Journal of Cell Biology. 156: 531-542. PMID 11815629 DOI: 10.1083/Jcb.200108084 |
0.409 |
|
| 2002 |
Nijhuis E, Lammers JJ, Koenderman L, Coffer PJ. Src kinases regulate PKB activation and modulate cytokine and chemoattractant-controlled neutrophil functioning. Journal of Leukocyte Biology. 71: 115-124. DOI: 10.1189/Jlb.71.1.115 |
0.386 |
|
| 2001 |
Birkenkamp K, Coffer P. Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors Biochemical Society Transactions. 31: 292-297. PMID 12546704 DOI: 10.1042/Bst0310292 |
0.426 |
|
| 2001 |
Hall DJ, Cui J, Bates ME, Stout BA, Koenderman L, Coffer PJ, Bertics PJ. Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability. Blood. 98: 2014-21. PMID 11567984 DOI: 10.1182/Blood.V98.7.2014 |
0.362 |
|
| 2001 |
Geijsen N, Uings IJ, Pals C, Armstrong J, McKinnon M, Raaijmakers JA, Lammers JW, Koenderman L, Coffer PJ. Cytokine-specific transcriptional regulation through an IL-5Ralpha interacting protein. Science (New York, N.Y.). 293: 1136-8. PMID 11498591 DOI: 10.1126/Science.1059157 |
0.3 |
|
| 2001 |
Bracke M, Lammers JJ, Coffer PJ, Koenderman L. Cytokine-induced inside-out activation of FcαR (CD89) is mediated by a single serine residue (S263) in the intracellular domain of the receptor Blood. 97: 3478-3483. PMID 11369640 DOI: 10.1182/Blood.V97.11.3478 |
0.364 |
|
| 2001 |
Geijsen N, Koenderman L, Coffer PJ. Specificity in cytokine signal transduction: lessons learned from the IL-3/IL-5/GM-CSF receptor family. Cytokine & Growth Factor Reviews. 12: 19-25. PMID 11312115 DOI: 10.1016/S1359-6101(00)00019-8 |
0.314 |
|
| 2001 |
Lian JP, Crossley L, Zhan Q, Huang R, Coffer P, Toker A, Robinson D, Badwey JA. Antagonists of Calcium Fluxes and Calmodulin Block Activation of the p21-Activated Protein Kinases in Neutrophils Journal of Immunology. 166: 2643-2650. PMID 11160327 DOI: 10.4049/Jimmunol.166.4.2643 |
0.317 |
|
| 2000 |
Dijkers PF, Medema RH, Pals C, Banerji L, Thomas NS, Lam EW, Burgering BM, Raaijmakers JA, Lammers JW, Koenderman L, Coffer PJ. Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). Molecular and Cellular Biology. 20: 9138-48. PMID 11094066 DOI: 10.1128/Mcb.20.24.9138-9148.2000 |
0.435 |
|
| 2000 |
Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Current Biology : Cb. 10: 1201-4. PMID 11050388 DOI: 10.1016/S0960-9822(00)00728-4 |
0.389 |
|
| 2000 |
Coffer PJ, Koenderman L, Groot RPD. The role of STATs in myeloid differentiation and leukemia. Oncogene. 19: 2511-2522. PMID 10851050 DOI: 10.1038/Sj.Onc.1203479 |
0.43 |
|
| 2000 |
Geijsen N, Dijkers PF, Lammers JJ, Koenderman L, Coffer PJ. Cytokine-mediated cPLA2 phosphorylation is regulated by multiple MAPK family members Febs Letters. 471: 83-88. PMID 10760518 DOI: 10.1016/S0014-5793(00)01373-9 |
0.4 |
|
| 2000 |
Pals CM, Verploegen SA, Raaijmakers JA, Lammers JW, Koenderman L, Coffer PJ. Identification of cytokine-regulated genes in human leukocytes in vivo. The Journal of Allergy and Clinical Immunology. 105: 760-8. PMID 10756227 DOI: 10.1067/Mai.2000.104382 |
0.368 |
|
| 2000 |
Bracke M, Graaf Evd, Lammers JJ, Coffer PJ, Koenderman L. In vivo priming of FcαR functioning on eosinophils of allergic asthmatics Journal of Leukocyte Biology. 68: 655-661. DOI: 10.1189/Jlb.68.5.655 |
0.35 |
|
| 2000 |
Verploegen S, Lammers JJ, Koenderman L, Coffer PJ. Identification and characterization of CKLiK, a novel granulocyte Ca++/calmodulin-dependent kinase Blood. 96: 3215-3223. DOI: 10.1182/Blood.V96.9.3215.H8003215_3215_3223 |
0.445 |
|
| 2000 |
Bracke M, Nijhuis E, Lammers JJ, Coffer PJ, Koenderman L. A critical role for PI 3-kinase in cytokine-induced Fcα-receptor activation Blood. 95: 2037-2043. DOI: 10.1182/Blood.V95.6.2037 |
0.395 |
|
| 2000 |
Versteeg HH, Nijhuis E, Brink GRVD, Evertzen M, Pynaert GN, Deventer SJHV, Coffer PJ, Peppelenbosch MP. A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein. Biochemical Journal. 350: 717-722. DOI: 10.1042/Bj3500717 |
0.382 |
|
| 1999 |
Geijsen N, Spaargaren M, Raaijmakers JA, Lammers JJ, Koenderman L, Coffer PJ. Association of RACK1 and PKCβ with the common β-chain of the IL-5/IL-3/GM-CSF receptor Oncogene. 18: 5126-5130. PMID 10490850 DOI: 10.1038/Sj.Onc.1202896 |
0.358 |
|
| 1999 |
Puijenbroek Av, Saag Pvd, Coffer P. Cytokine Signal Transduction in P19 Embryonal Carcinoma Cells: Regulation of Stat3-Mediated Transactivation Occurs Independently of p21ras-Erk Signaling Experimental Cell Research. 251: 465-476. PMID 10471331 DOI: 10.1006/Excr.1999.4576 |
0.445 |
|
| 1999 |
M'Rabet L, Coffer PJ, Wolthuis RMF, Zwartkruis F, Koenderman L, Bos JL. Differential fMet-Leu-Phe- and platelet-activating factor-induced signaling toward Ral activation in primary human neutrophils Journal of Biological Chemistry. 274: 21847-21852. PMID 10419502 DOI: 10.1074/Jbc.274.31.21847 |
0.359 |
|
| 1999 |
Dijkers PF, van Dijk TB, de Groot RP, Raaijmakers JA, Lammers JW, Koenderman L, Coffer PJ. Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor. Oncogene. 18: 3334-42. PMID 10362354 DOI: 10.1038/sj.onc.1202678 |
0.319 |
|
| 1999 |
Geijsen N, Delft Sv, Raaijmakers JAM, Lammers JJ, Collard JG, Koenderman L, Coffer PJ. Regulation of p21rac activation in human neutrophils. Blood. 94: 1121-1130. DOI: 10.1182/Blood.V94.3.1121.415K04_1121_1130 |
0.372 |
|
| 1998 |
Groot RPd, Coffer PJ, Koenderman L. Regulation of Proliferation, Differentiation and Survival by the IL-3/IL-5/GM-CSF Receptor Family Cellular Signalling. 10: 619-628. PMID 9794243 DOI: 10.1016/S0898-6568(98)00023-0 |
0.323 |
|
| 1998 |
Coffer PJ, Jin J, Woodgett JR. Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation Biochemical Journal. 335: 1-13. PMID 9742206 DOI: 10.1042/Bj3350001 |
0.561 |
|
| 1998 |
M'Rabet L, Coffer P, Zwartkruis F, Franke B, Segal AW, Koenderman L, Bos JL. Activation of the small GTPase Rap1 in human neutrophils Blood. 92: 2133-2140. PMID 9731072 DOI: 10.1182/Blood.V92.6.2133.418K19_2133_2140 |
0.347 |
|
| 1998 |
Ueki K, Yamamoto-Honda R, Kaburagi Y, Yamauchi T, Tobe K, Burgering BM, Coffer PJ, Komuro I, Akanuma Y, Yazaki Y, Kadowaki T. Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis. The Journal of Biological Chemistry. 273: 5315-22. PMID 9478990 DOI: 10.1074/Jbc.273.9.5315 |
0.336 |
|
| 1998 |
Coffer PJ, Schweizer RC, Dubois GR, Maikoe T, Lammers JJ, Koenderman L. Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5 Blood. 91: 2547-2557. DOI: 10.1182/Blood.V91.7.2547.2547_2547_2557 |
0.407 |
|
| 1997 |
Tanti J, Grillo S, Grémeaux T, Coffer PJ, Obberghen EV, Marchand-Brustel YL. Potential role of protein kinase B in glucose transporter 4 translocation in adipocytes. Endocrinology. 138: 2005-2010. PMID 9112399 DOI: 10.1210/Endo.138.5.5136 |
0.35 |
|
| 1997 |
Kauffmann-Zeh A, Rodriguez-Viciana P, Ulrich E, Gilbert C, Coffer P, Downward J, Evan G. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB Nature. 385: 544-548. PMID 9020362 DOI: 10.1038/385544A0 |
0.347 |
|
| 1997 |
Groot RPd, Dijk TBv, Caldenhoven E, Coffer PJ, Raaijmakers JAM, Lammers JJ, Koenderman L. Activation of 12-O-Tetradecanoylphorbol-13-acetate Response Element- and Dyad Symmetry Element-dependent Transcription by Interleukin-5 Is Mediated by Jun N-terminal Kinase/Stress-activated Protein Kinase Kinases Journal of Biological Chemistry. 272: 2319-2325. PMID 8999940 DOI: 10.1074/Jbc.272.4.2319 |
0.375 |
|
| 1997 |
Coffer PJ, Schweizer R, Malkoe T, Raaljmakers J, Lammers J-, Koenderman L. Analysis of activation and function of PI-3K and MEK-ERK signal transduction in human granulocytes Immunology Letters. 56: 209. DOI: 10.1016/S0165-2478(97)85834-8 |
0.313 |
|
| 1997 |
Bracke M, Coffer PJ, Schweizer RC, Lammers J-, Koenderman L. Analysis of signal transduction pathways regulating cytokine mediated Fcα receptor activation on human eosinophils Immunology Letters. 56: 36. DOI: 10.1016/S0165-2478(97)85135-8 |
0.36 |
|
| 1995 |
Burgering BMT, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction Nature. 376: 599-602. PMID 7637810 DOI: 10.1038/376599A0 |
0.359 |
|
| 1995 |
Lütticken C, Coffer P, Yuan J, Schwartz C, Caldenhoven E, Schindler C, Kruijer W, Heinrich PC, Horn F. Interleukin-6-Induced Serine Phosphorylation Of Transcription Factor Aprf : Evidence For A Role In Interleukin-6 Target Gene Induction Febs Letters. 360: 137-143. PMID 7533107 DOI: 10.1016/0014-5793(95)00076-L |
0.38 |
|
| 1994 |
Coffer PJ, Woodgett JR. Differential Subcellular Localization of Two Isoforms of p70 S6 Protein Kinase Biochemical and Biophysical Research Communications. 198: 780-786. PMID 8297390 DOI: 10.1006/Bbrc.1994.1112 |
0.563 |
|
| 1991 |
Grove JR, Banerjee P, Balasubramanyam A, Coffer PJ, Price DJ, Avruch J, Woodgett JR. Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Molecular and Cellular Biology. 11: 5541-50. PMID 1922062 DOI: 10.1128/mcb.11.11.5541-5550.1991 |
0.448 |
|
| 1991 |
Coffer PJ, Woodgett JR. Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families European Journal of Biochemistry. 201: 475-481. PMID 1718748 DOI: 10.1111/J.1432-1033.1991.Tb16305.X |
0.538 |
|
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