Year |
Citation |
Score |
2019 |
Kawachi T, Tanaka S, Fukuda A, Sumii Y, Setiawan A, Kotoku N, Kobayashi M, Arai M. Target Identification of the Marine Natural Products Dictyoceratin-A and -C as Selective Growth Inhibitors in Cancer Cells Adapted to Hypoxic Environments. Marine Drugs. 17. PMID 30857246 DOI: 10.3390/Md17030163 |
0.668 |
|
2018 |
Ishida R, Matsumoto H, Ichii S, Kobayashi M, Arai M, Kotoku N. Structure-Activity Relationship of Biakamide, Selective Growth Inhibitors under Nutrient-starved Condition from Marine Sponge. Chemical & Pharmaceutical Bulletin. PMID 30429430 DOI: 10.1248/Cpb.C18-00587 |
0.363 |
|
2017 |
Kamiya K, Arai M, Setiawan A, Kobayashi M. Anti-dormant Mycobacterial Activity of Viomellein and Xanthomegnin, Naphthoquinone Dimers Produced by Marine- derived Aspergillus sp. Natural Product Communications. 12: 579-581. PMID 30520600 DOI: 10.1177/1934578X1701200428 |
0.351 |
|
2017 |
Kotoku N, Ishida R, Matsumoto H, Arai M, Toda K, Setiawan A, Muraoka O, Kobayashi M. Biakamides A-D, unique polyketides from a marine sponge, act as selective growth inhibitors of tumor cells adapted to nutrient starvation. The Journal of Organic Chemistry. PMID 28090774 DOI: 10.1021/Acs.Joc.6B02948 |
0.374 |
|
2017 |
Kotoku N, Ito A, Shibuya S, Mizuno K, Takeshima A, Nogata M, Kobayashi M. Short-step synthesis and structure-activity relationship of cortistatin A analogs Tetrahedron. 73: 1342-1349. DOI: 10.1016/J.Tet.2017.01.042 |
0.361 |
|
2016 |
Arai M, Shin D, Kamiya K, Ishida R, Setiawan A, Kotoku N, Kobayashi M. Marine spongean polybrominated diphenyl ethers, selective growth inhibitors against the cancer cells adapted to glucose starvation, inhibits mitochondrial complex II. Journal of Natural Medicines. PMID 27449332 DOI: 10.1007/S11418-016-1025-X |
0.325 |
|
2016 |
Arai M, Kamiya K, Shin D, Matsumoto H, Hisa T, Setiawan A, Kotoku N, Kobayashi M. N-Methylniphatyne A, a New 3-Alkylpyridine Alkaloid as an Inhibitor of the Cancer Cells Adapted to Nutrient Starvation, from an Indonesian Marine Sponge of Xestospongia sp. Chemical & Pharmaceutical Bulletin. 64: 766-71. PMID 27373630 DOI: 10.1248/Cpb.C16-00118 |
0.392 |
|
2016 |
Kotoku N, Arai M, Kobayashi M. Search for Anti-angiogenic Substances from Natural Sources. Chemical & Pharmaceutical Bulletin. 64: 128-34. PMID 26833441 DOI: 10.1248/Cpb.C15-00744 |
0.305 |
|
2015 |
Sumii Y, Kotoku N, Fukuda A, Kawachi T, Arai M, Kobayashi M. Structure-Activity Relationship and in Vivo Anti-Tumor Evaluations of Dictyoceratin-A and -C, Hypoxia-Selective Growth Inhibitors from Marine Sponge. Marine Drugs. 13: 7419-32. PMID 26694423 DOI: 10.3390/Md13127074 |
0.705 |
|
2015 |
Arai M, Kamiya K, Pruksakorn P, Sumii Y, Kotoku N, Joubert JP, Moodley P, Han C, Shin D, Kobayashi M. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorganic & Medicinal Chemistry. 23: 3534-41. PMID 25934225 DOI: 10.1016/J.Bmc.2015.04.033 |
0.692 |
|
2015 |
Sumii Y, Kotoku N, Fukuda A, Kawachi T, Sumii Y, Arai M, Kobayashi M. Enantioselective synthesis of dictyoceratin-A (smenospondiol) and -C, hypoxia-selective growth inhibitors from marine sponge. Bioorganic & Medicinal Chemistry. 23: 966-75. PMID 25659617 DOI: 10.1016/J.Bmc.2015.01.021 |
0.68 |
|
2014 |
Kotoku N, Higashimoto K, Kurioka M, Arai M, Fukuda A, Sumii Y, Sowa Y, Sakai T, Kobayashi M. Xylarianaphthol-1, a novel dinaphthofuran derivative, activates p21 promoter in a p53-independent manner. Bioorganic & Medicinal Chemistry Letters. 24: 3389-91. PMID 24939757 DOI: 10.1016/J.Bmcl.2014.05.083 |
0.662 |
|
2014 |
Arai M, Kawachi T, Sato H, Setiawan A, Kobayashi M. Marine spongian sesquiterpene phenols, dictyoceratin-C and smenospondiol, display hypoxia-selective growth inhibition against cancer cells. Bioorganic & Medicinal Chemistry Letters. 24: 3155-7. PMID 24865416 DOI: 10.1016/J.Bmcl.2014.04.116 |
0.357 |
|
2014 |
Kotoku N, Nakata C, Kawachi T, Sato T, Guo XH, Ito A, Sumii Y, Arai M, Kobayashi M. Synthesis and evaluation of effective photoaffinity probe molecule of furospinosulin-1, a hypoxia-selective growth inhibitor. Bioorganic & Medicinal Chemistry. 22: 2102-12. PMID 24631363 DOI: 10.1016/J.Bmc.2014.02.026 |
0.652 |
|
2014 |
Arai M, Han C, Yamano Y, Setiawan A, Kobayashi M. Aaptamines, marine spongean alkaloids, as anti-dormant mycobacterial substances. Journal of Natural Medicines. 68: 372-6. PMID 24414399 DOI: 10.1007/S11418-013-0811-Y |
0.405 |
|
2014 |
Arai M, Yamano Y, Setiawan A, Kobayashi M. Identification of the target protein of agelasine D, a marine sponge diterpene alkaloid, as an anti-dormant mycobacterial substance. Chembiochem : a European Journal of Chemical Biology. 15: 117-23. PMID 24243718 DOI: 10.1002/Cbic.201300470 |
0.318 |
|
2013 |
Kotoku N, Mizushima K, Tamura S, Kobayashi M. Synthetic studies of cortistatin A analogue from the CD-ring fragment of vitamin D₂. Chemical & Pharmaceutical Bulletin. 61: 1024-9. PMID 24088693 DOI: 10.1248/Cpb.C13-00375 |
0.304 |
|
2012 |
Kotoku N, Sumii Y, Hayashi T, Tamura S, Kawachi T, Shiomura S, Arai M, Kobayashi M. Creation of readily accessible and orally active analogue of cortistatin a. Acs Medicinal Chemistry Letters. 3: 673-7. PMID 24900528 DOI: 10.1021/Ml300143D |
0.699 |
|
2012 |
Yamano Y, Arai M, Kobayashi M. Neamphamide B, new cyclic depsipeptide, as an anti-dormant mycobacterial substance from a Japanese marine sponge of Neamphius sp. Bioorganic & Medicinal Chemistry Letters. 22: 4877-81. PMID 22704240 DOI: 10.1016/J.Bmcl.2012.05.071 |
0.402 |
|
2012 |
Arai M, Yamano Y, Fujita M, Setiawan A, Kobayashi M. Stylissamide X, a new proline-rich cyclic octapeptide as an inhibitor of cell migration, from an Indonesian marine sponge of Stylissa sp. Bioorganic & Medicinal Chemistry Letters. 22: 1818-21. PMID 22260773 DOI: 10.1016/J.Bmcl.2011.10.023 |
0.371 |
|
2011 |
Pruksakorn P, Arai M, Liu L, Moodley P, Jacobs WR, Kobayashi M. Action-mechanism of trichoderin A, an anti-dormant mycobacterial aminolipopeptide from marine sponge-derived Trichoderma sp. Biological & Pharmaceutical Bulletin. 34: 1287-90. PMID 21804219 DOI: 10.1248/Bpb.34.1287 |
0.332 |
|
2011 |
Kotoku N, Sumii Y, Kobayashi M. Stereoselective synthesis of core structure of cortistatin A. Organic Letters. 13: 3514-7. PMID 21651309 DOI: 10.1021/Ol201327U |
0.684 |
|
2011 |
Kong D, Yamori T, Kobayashi M, Duan H. Antiproliferative and antiangiogenic activities of smenospongine, a marine sponge sesquiterpene aminoquinone. Marine Drugs. 9: 154-61. PMID 21566792 DOI: 10.3390/Md9020154 |
0.303 |
|
2011 |
Arai M, Hayashi A, Sobou M, Ishida S, Kawachi T, Kotoku N, Kobayashi M. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. Journal of Natural Medicines. 65: 149-56. PMID 21042868 DOI: 10.1007/S11418-010-0477-7 |
0.316 |
|
2011 |
Kotoku N, Sumii Y, Hayashi T, Kobayashi M. Synthetic study of carbocyclic core of cortistatin a, an anti-angiogenic steroidal alkaloid from marine sponge Heterocycles. 83: 1535-1552. DOI: 10.3987/Com-11-12195 |
0.668 |
|
2011 |
Kotoku N, Fujioka S, Nakata C, Yamada M, Sumii Y, Kawachi T, Arai M, Kobayashi M. Concise synthesis and structure-activity relationship of furospinosulin-1, a hypoxia-selective growth inhibitor from marine sponge Tetrahedron. 67: 6673-6678. DOI: 10.1016/J.Tet.2011.05.009 |
0.69 |
|
2010 |
Arai M, Kawachi T, Setiawan A, Kobayashi M. Hypoxia-selective growth inhibition of cancer cells by furospinosulin-1, a furanosesterterpene isolated from an Indonesian marine sponge. Chemmedchem. 5: 1919-26. PMID 20839272 DOI: 10.1002/Cmdc.201000302 |
0.307 |
|
2010 |
Pruksakorn P, Arai M, Kotoku N, Vilchèze C, Baughn AD, Moodley P, Jacobs WR, Kobayashi M. Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria. Bioorganic & Medicinal Chemistry Letters. 20: 3658-63. PMID 20483615 DOI: 10.1016/J.Bmcl.2010.04.100 |
0.41 |
|
2009 |
Arai M, Ishida S, Setiawan A, Kobayashi M. Haliclonacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Haliclona sp. Chemical & Pharmaceutical Bulletin. 57: 1136-8. PMID 19801875 DOI: 10.1248/Cpb.57.1136 |
0.41 |
|
2009 |
Hayashi A, Arai M, Fujita M, Kobayashi M. Pyripyropenes, fungal sesquiterpenes conjugated with alpha-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells. Biological & Pharmaceutical Bulletin. 32: 1261-5. PMID 19571395 DOI: 10.1248/Bpb.32.1261 |
0.346 |
|
2009 |
Suna H, Arai M, Tsubotani Y, Hayashi A, Setiawan A, Kobayashi M. Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. Bioorganic & Medicinal Chemistry. 17: 3968-72. PMID 19414266 DOI: 10.1016/J.Bmc.2009.04.025 |
0.303 |
|
2009 |
Tamura S, Shiomi A, Kaneko M, Ye Y, Yoshida M, Yoshikawa M, Kimura T, Kobayashi M, Murakami N. New Rev-export inhibitor from Alpinia galanga and structure-activity relationship. Bioorganic & Medicinal Chemistry Letters. 19: 2555-7. PMID 19342232 DOI: 10.1016/J.Bmcl.2009.03.047 |
0.317 |
|
2008 |
Kotoku N, Hiramatsu A, Tsujita H, Hirakawa Y, Sanagawa M, Aoki S, Kobayashi M. Structure-activity relationships study of bastadin 6, an anti-angiogenic brominated-tyrosine derived metabolite from marine sponge. Archiv Der Pharmazie. 341: 568-77. PMID 18763716 DOI: 10.1002/Ardp.200700231 |
0.355 |
|
2008 |
Kotoku N, Tamada N, Hayashi A, Kobayashi M. Synthesis of BC-ring model of globostellatic acid X methyl ester, an anti-angiogenic substance from marine sponge. Bioorganic & Medicinal Chemistry Letters. 18: 3532-5. PMID 18492609 DOI: 10.1016/J.Bmcl.2008.05.018 |
0.322 |
|
2008 |
Kotoku N, Sumii Y, Hayashi T, Kobayashi M. Synthesis of CD-ring structure of cortistatin A, an anti-angiogenic steroidal alkaloid from marine sponge Tetrahedron Letters. 49: 7078-7081. DOI: 10.1016/J.Tetlet.2008.09.157 |
0.662 |
|
2007 |
Wei H, Inada H, Hayashi A, Higashimoto K, Pruksakorn P, Kamada S, Arai M, Ishida S, Kobayashi M. Prenylterphenyllin and its dehydroxyl analogs, new cytotoxic substances from a marine-derived Fungus Aspergillus candidus IF10. The Journal of Antibiotics. 60: 586-90. PMID 17917243 DOI: 10.1038/Ja.2007.75 |
0.43 |
|
2007 |
Aoki S, Watanabe Y, Tanabe D, Arai M, Suna H, Miyamoto K, Tsujibo H, Tsujikawa K, Yamamoto H, Kobayashi M. Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids. Bioorganic & Medicinal Chemistry. 15: 6758-62. PMID 17765550 DOI: 10.1016/J.Bmc.2007.08.017 |
0.353 |
|
2007 |
Aoki S, Sanagawa M, Watanabe Y, Setiawan A, Arai M, Kobayashi M. Novel isomarabarican triterpenes, exhibiting selective anti-proliferative activity against vascular endothelial cells, from marine sponge Rhabdastrella globostellata. Bioorganic & Medicinal Chemistry. 15: 4818-28. PMID 17524651 DOI: 10.1016/J.Bmc.2007.04.070 |
0.353 |
|
2007 |
Kotoku N, Narumi F, Kato T, Yamaguchi M, Kobayashi M. Stereoselective total synthesis of arenastatin A, a spongean cytotoxic depsipeptide Tetrahedron Letters. 48: 7147-7150. DOI: 10.1016/J.Tetlet.2007.07.193 |
0.309 |
|
2007 |
Aoki S, Watanabe Y, Tanabe D, Setiawan A, Arai M, Kobayashi M. Cortistatins J, K, L, novel abeo-9(10-19)-androstane-type steroidal alkaloids with isoquinoline unit, from marine sponge Corticium simplex Tetrahedron Letters. 48: 4485-4488. DOI: 10.1016/J.Tetlet.2007.05.003 |
0.332 |
|
2007 |
Watanabe Y, Aoki S, Tanabe D, Setiawan A, Kobayashi M. Cortistatins E, F, G, and H, four novel steroidal alkaloids from marine sponge Corticium simplex Tetrahedron. 63: 4074-4079. DOI: 10.1016/J.Tet.2007.02.112 |
0.386 |
|
2006 |
Aoki S, Cho SH, Hiramatsu A, Kotoku N, Kobayashi M. Bastadins, cyclic tetramers of brominated-tyrosine derivatives, selectively inhibit the proliferation of endothelial cells. Journal of Natural Medicines. 60: 231-235. PMID 29435890 DOI: 10.1007/S11418-006-0045-3 |
0.369 |
|
2006 |
Aoki S, Watanabe Y, Sanagawa M, Setiawan A, Kotoku N, Kobayashi M. Cortistatins A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex. Journal of the American Chemical Society. 128: 3148-9. PMID 16522087 DOI: 10.1021/Ja057404H |
0.402 |
|
2006 |
Wei H, Itoh T, Kotoku N, Kobayashi M. Shimalactones, neuritogenic polyketides from A marine-derived fungus Emericella variecolor GF10 Heterocycles. 68: 111-123. DOI: 10.3987/Com-05-10589 |
0.421 |
|
2005 |
Wei H, Itoh T, Kinoshita M, Kotoku N, Aoki S, Kobayashi M. Shimalactone A, a novel polyketide, from marine-derived fungus Emericella variecolor GF10 Tetrahedron. 61: 8054-8058. DOI: 10.1016/J.Tet.2005.05.105 |
0.387 |
|
2004 |
Kawanishi M, Kotoku N, Itagaki S, Horii T, Kobayashi M. Structure-activity relationship of anti-malarial spongean peroxides having a 3-methoxy-1,2-dioxane structure. Bioorganic & Medicinal Chemistry. 12: 5297-307. PMID 15388157 DOI: 10.1016/J.Bmc.2004.04.051 |
0.322 |
|
2004 |
Aoki S, Kong D, Matsui K, Rachmat R, Kobayashi M. Sesquiterpene aminoquinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells. Chemical & Pharmaceutical Bulletin. 52: 935-7. PMID 15304984 DOI: 10.1248/Cpb.52.935 |
0.317 |
|
2004 |
Murakami N, Tamura S, Koyama K, Sugimoto M, Maekawa R, Kobayashi M. New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity. Bioorganic & Medicinal Chemistry Letters. 14: 2597-601. PMID 15109660 DOI: 10.1016/J.Bmcl.2004.02.080 |
0.349 |
|
2004 |
Wei H, Itoh T, Kinoshita M, Nakai Y, Kurotaki M, Kobayashi M. Cytotoxic sesterterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF10 Tetrahedron. 60: 6015-6019. DOI: 10.1016/J.Tet.2004.05.021 |
0.389 |
|
2004 |
Aoki S, Cao L, Matsui K, Rachmat R, Akiyama SI, Kobayashi M. Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp Tetrahedron. 60: 7053-7059. DOI: 10.1016/J.Tet.2003.07.020 |
0.341 |
|
2003 |
Itoh T, Kinoshita M, Wei H, Kobayashi M. Stereostructure of komodoquinone A, a neuritogenic anthracycline, from marine Streptomyces sp. KS3. Chemical & Pharmaceutical Bulletin. 51: 1402-4. PMID 14646317 DOI: 10.1248/Cpb.51.1402 |
0.353 |
|
2003 |
Murakami N, Kawanishi M, Mostaqul HM, Li J, Itagaki S, Horii T, Kobayashi M. New anti-malarial peroxides with in vivo potency derived from spongean metabolites. Bioorganic & Medicinal Chemistry Letters. 13: 4081-4. PMID 14592512 DOI: 10.1016/J.Bmcl.2003.08.073 |
0.337 |
|
2003 |
Itoh T, Kinoshita M, Aoki S, Kobayashi M. Komodoquinone A, a novel neuritogenic anthracycline, from marine Streptomyces sp. KS3. Journal of Natural Products. 66: 1373-7. PMID 14575440 DOI: 10.1021/Np030212K |
0.415 |
|
2003 |
Ohta E, Okada H, Ohta S, Kobayashi M, Kitagawa I, Horiike S, Takahashi T, Hosoya H, Yamamoto K, Ikegami S. Malformation of immature starfish oocytes by theonellapeptolide Ie, a tridecapeptide lactone from a marine sponge Petrosia species, through disturbance of cortical F-actin distribution Bioscience, Biotechnology and Biochemistry. 67: 1908-1915. PMID 14519975 DOI: 10.1271/Bbb.67.1908 |
0.565 |
|
2003 |
Aoki S, Wei H, Matsui K, Rachmat R, Kobayashi M. Pyridoacridine alkaloids inducing neuronal differentiation in a neuroblastoma cell line, from marine sponge Biemna fortis. Bioorganic & Medicinal Chemistry. 11: 1969-73. PMID 12670647 DOI: 10.1016/S0968-0896(03)00086-5 |
0.341 |
|
2002 |
Aoki S, Naka Y, Itoh T, Furukawa T, Rachmat R, Akiyama S, Kobayashi M. Lembehsterols A and B, novel sulfated sterols inhibiting thymidine phosphorylase, from the marine sponge Petrosia strongylata. Chemical & Pharmaceutical Bulletin. 50: 827-30. PMID 12045340 DOI: 10.1248/Cpb.50.827 |
0.411 |
|
2002 |
Murakami N, Kawanishi M, Itagaki S, Horii T, Kobayashi M. New readily accessible peroxides with high anti-malarial potency. Bioorganic & Medicinal Chemistry Letters. 12: 69-72. PMID 11738575 DOI: 10.1016/S0960-894X(01)00673-4 |
0.339 |
|
2002 |
Aoki S, Matsui K, Wei H, Murakami N, Kobayashi M. Structure-activity relationship of neuritogenic spongean acetylene alcohols, lembehynes Tetrahedron. 58: 5417-5422. DOI: 10.1016/S0040-4020(02)00519-7 |
0.34 |
|
2001 |
Aoki S, Ye Y, Higuchi K, Takashima A, Tanaka Y, Kitagawa I, Kobayashi M. Novel neuronal nitric oxide synthase (nNOS) selective inhibitor, aplysinopsin-type indole alkaloid, from marine sponge Hyrtios erecta Chemical and Pharmaceutical Bulletin. 49: 1372-1374. PMID 11605676 DOI: 10.1248/Cpb.49.1372 |
0.636 |
|
2001 |
Murakami N, Mostaqul HM, Tamura S, Itagaki S, Horii T, Kobayashi M. New anti-malarial flavonol glycoside from Hydrangeae Dulcis Folium Bioorganic and Medicinal Chemistry Letters. 11: 2445-2447. PMID 11549443 DOI: 10.1016/S0960-894X(01)00467-X |
0.359 |
|
2001 |
Murakami N, Sugimoto M, Nakajima T, Kawanishi M, Tsutsui Y, Kobayashi M. Participation of the conjugated diene part for potent cytotoxicity of callystatin A, a spongean polyketide. Bioorganic & Medicinal Chemistry. 8: 2651-61. PMID 11092550 DOI: 10.1016/S0968-0896(00)00199-1 |
0.389 |
|
2001 |
Murakami N, Wang W, Tamura S, Kobayashi M. Synthesis and biological property of carba and 20-deoxo analogues of arenastatin A. Bioorganic & Medicinal Chemistry Letters. 10: 1823-6. PMID 10969977 DOI: 10.1016/S0960-894X(00)00356-5 |
0.315 |
|
2001 |
Murakami N, Kawanishi M, Itagaki S, Horii T, Kobayashi M. Facile construction of 6-carbomethoxymethyl-3-methoxy-1,2-dioxane, a core structure of spongean anti-malarial peroxides Tetrahedron Letters. 42: 7281-7285. DOI: 10.1016/S0040-4039(01)01493-9 |
0.301 |
|
2001 |
Aoki S, Okano M, Matsui K, Itoh T, Satari R, Akiyama SI, Kobayashi M. Brianthein A, a novel briarane-type diterpene reversing multidrug resistance in human carcinoma cell line, from the gorgonian Briareum excavatum Tetrahedron. 57: 8951-8957. DOI: 10.1016/S0040-4020(01)00894-8 |
0.382 |
|
2001 |
Murakami N, Tamura S, Wang W, Takagi T, Kobayashi M. Synthesis of stable analogs in blood and conformational analysis of arenastatin A, a potent cytotoxic spongean depsipeptide Tetrahedron. 57: 4323-4336. DOI: 10.1016/S0040-4020(01)00339-8 |
0.308 |
|
2001 |
Aoki S, Nemoto N, Kobayashi Y, Kobayashi M, Kitagawa I. Molecular modeling of 5-desacetylaltohyrtin A, a spongean cytotoxic macrolide Tetrahedron. 57: 2289-2292. DOI: 10.1016/S0040-4020(01)00111-9 |
0.608 |
|
2000 |
Aoki S, Matsui K, Tanaka K, Satari R, Kobayashi M. Lembehyne a , a novel neuritogenic polyacetylene, from a marine sponge of Haliclona sp Tetrahedron. 56: 9945-9948. DOI: 10.1016/S0040-4020(00)00973-X |
0.398 |
|
2000 |
Murakami N, Wang W, Ohyabu N, Ito T, Tamura S, Aoki S, Kobayashi M, Kitagawa I. Synthesis of amide analogs of arenastatin A Tetrahedron. 56: 9121-9128. DOI: 10.1016/S0040-4020(00)00766-3 |
0.593 |
|
2000 |
Aoki S, Higuchi K, Ye Y, Satari R, Kobayashi M. Melophlins A and B, Novel Tetramic Acids Reversing the Phenotype of ras-Transformed Cells, from the Marine Sponge Melophlus sarassinorum Tetrahedron. 56: 1833-1836. DOI: 10.1016/S0040-4020(00)00092-2 |
0.332 |
|
1999 |
Kuwajima H, Taneda Y, Chen WZ, Kawanishi T, Hori K, Taniyama T, Kobayashi M, Ren J, Kitagawa I. Variation of chemical constituents in processed licorice roots: Quantitative determination of saponin and flavonoid constituents in bark removed and roasted licorice roots Yakugaku Zasshi. 119: 945-955. PMID 10630100 DOI: 10.1248/Yakushi1947.119.12_945 |
0.566 |
|
1999 |
Kobayashi M, Kitagawa I. Marine spongean cytotoxins Journal of Natural Toxins. 8: 249-258. PMID 10410335 |
0.582 |
|
1999 |
Aoki S, Higuchi K, Kato A, Murakami N, Kobayashi M. Myrmekiosides a and b, novel mono-o-alkyl-diglycosylglycerols reversing tumor cell morphology of ras-transformed cells from a marine sponge of myrmekioderma sp Tetrahedron. 55: 14865-14870. DOI: 10.1016/S0040-4020(99)00970-9 |
0.358 |
|
1999 |
Aoki S, Setiawan A, Yoshioka Y, Higuchi K, Fudetani R, Chen Z, Sumizawa T, Akiyama S, Kobayashi M. Reversal of multidrug resistance in human carcinoma cell line by agosterols, marine spongean sterols Tetrahedron. 55: 13965-13972. DOI: 10.1016/S0040-4020(99)00870-4 |
0.381 |
|
1998 |
Murakami N, Umezome T, Mahmud T, Sugimoto M, Kobayashi M, Wataya Y, Kim HS. Anti-malarial activities of acylated bruceolide derivatives. Bioorganic & Medicinal Chemistry Letters. 8: 459-62. PMID 9871598 DOI: 10.1016/S0960-894X(98)00045-6 |
0.655 |
|
1998 |
Kitagawa I, Chen WZ, Taniyama T, Harada E, Hori K, Kobayashi M, Ren J. Quantitative determination of constituents in various licorice roots by means of high performance liquid chromatography Yakugaku Zasshi. 118: 519-528. PMID 9868382 DOI: 10.1248/Yakushi1947.118.11_519 |
0.57 |
|
1998 |
Kitagawa I, Hori K, Kawanishi T, Kobayashi M, Kawanishi F. On the constituents of the root of Fukuchiyama-jio, the hybrid of Rehmannia glutinosa var. purpurea and R. glutinosa forma hueichingensis Yakugaku Zasshi. 118: 464-475. PMID 9800518 DOI: 10.1248/Yakushi1947.118.10_464 |
0.617 |
|
1998 |
Kobayashi M, Wang W, Tsutsui Y, Sugimoto M, Murakami N. Absolute stereostructure and total synthesis of leptomycin B Tetrahedron Letters. 39: 8291-8294. DOI: 10.1016/S0040-4039(98)01809-7 |
0.317 |
|
1998 |
Aoki S, Yoshioka Y, Miyamoto Y, Higuchi K, Setiawan A, Murakami N, Chen Z, Sumizawa T, Akiyama S, Kobayashi M. Agosterol A, a novel polyhydroxylated sterol acetate reversing multidrug resistance from a marine sponge of Spongia sp. Tetrahedron Letters. 39: 6303-6306. DOI: 10.1016/S0040-4039(98)01336-7 |
0.346 |
|
1998 |
Murakami N, Wang W, Aoki M, Tsutsui Y, Sugimoto M, Kobayashi M. Total synthesis of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata Tetrahedron Letters. 39: 2349-2352. DOI: 10.1016/S0040-4039(98)00151-8 |
0.325 |
|
1997 |
Itoh N, Kimura T, Nakanishi H, Muto N, Kobayashi M, Kitagawa I, Tanaka K. Metallothionein-independent hepatoprotection by zinc and sakuraso-saponin Toxicology Letters. 93: 135-140. PMID 9486949 DOI: 10.1016/S0378-4274(97)00086-6 |
0.545 |
|
1997 |
Kobayashi M, Mahmud T, Yoshioka N, Shibuya H, Kitagawa I. Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis Chemical and Pharmaceutical Bulletin. 45: 1615-1619. PMID 9353889 DOI: 10.1248/Cpb.45.1615 |
0.732 |
|
1997 |
Utoguchi N, Nakata T, Cheng HH, Ikeda K, Makimoto H, Mu Y, Nakagawa S, Kobayashi M, Kitagawa I, Mayumi T. Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion Inflammation. 21: 223-233. PMID 9187964 DOI: 10.1023/A:1027374321718 |
0.596 |
|
1997 |
Murakami N, Wang W, Aoki M, Tsutsui Y, Higuchi K, Aoki S, Kobayashi M. Absolute stereostructure of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata Tetrahedron Letters. 38: 5533-5536. DOI: 10.1016/S0040-4039(97)01194-5 |
0.348 |
|
1997 |
Kobayashi M, Higuchi K, Murakami N, Tajima H, Aoki S. Callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata Tetrahedron Letters. 38: 2859-2862. DOI: 10.1016/S0040-4039(97)00482-6 |
0.395 |
|
1997 |
Kobayashi M, Mahmud T, Umezome T, Wang W, Murakami N, Kitagawa I. The absolute stereostructures of the polyacetylenic constituents of Ginseng Radix Rubra Tetrahedron. 53: 15691-15700. DOI: 10.1016/S0040-4020(97)10026-6 |
0.706 |
|
1997 |
Itoh N, Morishita Y, Tanaka T, Muto N, Kobayashi M, Kitagawa I, Tanaka K. Metallothionein induction and hepatoprotection by echinoside A and sakuraso-saponin Phytotherapy Research. 11: 132-135. DOI: 10.1002/(Sici)1099-1573(199703)11:2<132::Aid-Ptr52>3.0.Co;2-Z |
0.547 |
|
1996 |
Kitagawa I, Mahmud T, Yokota K, Nakagawa S, Mayumi T, Kobayashi M, Shibuya H. Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica. Chemical & Pharmaceutical Bulletin. 44: 2009-14. PMID 8945767 DOI: 10.1248/Cpb.44.2009 |
0.748 |
|
1996 |
Kitagawa I, Wei H, Nagao S, Mahmud T, Hori K, Kobayashi M, Uji T, Shibuya H. Indonesian Medicinal Plants. XIV. Characterization of 3'-O-Caffeoylsweroside, a new secoiridoid glucoside, and kelampayosides A and B, two new phenolic apioglucosides, from the bark of Anthocephalus chinensis (Rubiaceae). Chemical & Pharmaceutical Bulletin. 44: 1162-7. PMID 8814946 DOI: 10.1248/Cpb.44.1162 |
0.729 |
|
1996 |
Kobayashi M, Mahmud T, Tajima H, Wang W, Aoki S, Nakagawa S, Mayumi T, Kitagawa I. Marine natural products. XXXVI. Biologically active polyacetylenes, adociacetylenes A, B, C, and D, from an Okinawan Marine sponge of Adocia sp. Chemical & Pharmaceutical Bulletin. 44: 720-4. PMID 8681403 DOI: 10.1248/Cpb.44.720 |
0.783 |
|
1996 |
Shinkai K, Akedo H, Mukai M, Imamura F, Isoai A, Kobayashi M, Kitagawa I. Inhibition of in vitro tumor cell invasion by ginsenoside Rg3. Japanese Journal of Cancer Research : Gann. 87: 357-62. PMID 8641966 DOI: 10.1111/J.1349-7006.1996.Tb00230.X |
0.571 |
|
1996 |
Hirata K, Nakagami H, Takashina J, Mahmud T, Kobayashi M, In Y, Ishida T, Miyamoto K. Novel violet pigment, nostocine a, an extracellular metabolite from cyanobacterium Nostoc spongiaeforme Heterocycles. 43: 1513-1519. DOI: 10.3987/Com-96-7494 |
0.62 |
|
1996 |
Kobayashi M, Aoki S, Gato K, Kitagawa I. Marine Natural Products. XXXVIII. Absolute Stereostructures of Altohyrtins A, B, and C and 5-Desacetylaltohyrtin A, Potent Cytotoxic Macrolides, from the Okinawan Marine Sponge Hyrtios altum Chemical & Pharmaceutical Bulletin. 44: 2142-2149. DOI: 10.1248/Cpb.44.2142 |
0.651 |
|
1996 |
Kobayashi M, Chen Y, Higuchi K, Aoki S, Kitagawa I. Marine Natural Products. XXXVII. Aragusteroketals A and C, Tow Novel Cytotoxic Steroids from a Marine Sponge of Xestospongia sp. Chemical & Pharmaceutical Bulletin. 44: 1840-1842. DOI: 10.1248/Cpb.44.1840 |
0.687 |
|
1995 |
Kitagawa I, Mahmud T, Kobayashi M, Roemantyo, Shibuya H. Taxol and its related taxoids from the needles of Taxus sumatrana. Chemical & Pharmaceutical Bulletin. 43: 365-7. PMID 7728941 DOI: 10.1248/Cpb.43.365 |
0.747 |
|
1995 |
Kobayashi M, Wang W, Ohyabu N, Kurosu M, Kitagawa I. Improved total synthesis and structure-activity relationship of arenastatin A, a potent cytotoxic spongean depsipeptide. Chemical & Pharmaceutical Bulletin. 43: 1598-600. PMID 7586087 DOI: 10.1248/Cpb.43.1598 |
0.653 |
|
1995 |
Kobayashi M, Chen YJ, Aoki S, In Y, Ishida T, Kitagawa I. Four new β-carboline alkaloids isolated from two Okinawan marine sponges of Xestospongia sp. and Haliclona sp.) Tetrahedron. 51: 3727-3736. DOI: 10.1016/0040-4020(95)95723-9 |
0.653 |
|
1994 |
Kobayashi M, Okamoto T, Hayashi K, Yokoyama N, Sasaki T, Kitagawa I. Marine natural products. XXXII. Absolute configurations of C-4 of the manoalide family, biologically active sesterterpenes from the marine sponge Hyrtios erecta. Chemical & Pharmaceutical Bulletin. 42: 265-70. PMID 8149454 DOI: 10.1248/Cpb.42.265 |
0.614 |
|
1994 |
Kobayashi M, Kawazoe K, Okamoto T, Sasaki T, Kitagawa I. Marine natural products. XXXI. Structure-activity correlation of a potent cytotoxic dimeric macrolide swinholide A, from the Okinawan marine sponge Theonella swinhoei, and its isomers. Chemical & Pharmaceutical Bulletin. 42: 19-26. PMID 8124763 |
0.602 |
|
1994 |
Shioda M, Kano K, Kobayashi M, Kitagawa I, Shoji M, Yoshida S, Ikegami S. Differential inhibition of eukaryotic DNA polymerases by halenaquinol sulfate, a p-hydroquinone sulfate obtained from a marine sponge. Febs Letters. 350: 249-52. PMID 8070573 DOI: 10.1016/0014-5793(94)00777-2 |
0.546 |
|
1994 |
Kitagawa I, Simanjuntak P, Hori K, Nagami N, Mahmud T, Shibuya H, Kobayashi M. Indonesian medicinal plants. VII. Seven new clerodane-type diterpenoids, peronemins A2, A3, B1, B2, B3, C1, and D1, from the leaves of Peronema canescens (Verbenaceae). Chemical & Pharmaceutical Bulletin. 42: 1050-5. PMID 8069955 DOI: 10.1248/Cpb.42.1050 |
0.742 |
|
1994 |
Kobayashi M, Kanzaki K, Katayama S, Ohashi K, Okada H, Ikegami S, Kitagawa I. Marine natural products. XXXIII. Theonellapeptolide IId, a new tridecapeptide lactone from the Okinawan marine sponge Theonella swinhoei. Chemical & Pharmaceutical Bulletin. 42: 1410-5. PMID 7923463 DOI: 10.1248/Cpb.42.1410 |
0.626 |
|
1994 |
Kobayashi M, Aoki S, Gato K, Matsunami K, Kurosu M, Kitagawa I. Marine natural products. XXXIV. Trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. separated from the marine sponge Hyrtios altum. Chemical & Pharmaceutical Bulletin. 42: 2449-51. PMID 7697760 DOI: 10.1248/Cpb.42.2449 |
0.65 |
|
1994 |
Kobayashi M, Kurosu M, Wang W, Kitagawa I. A Total Synthesis Of Arenastatin A, An Extremely Potent Cytotoxic Depsipeptide, From The Okinawan Marine Sponge Dysidea Arenaria Chemical & Pharmaceutical Bulletin. 42: 2394-2396. DOI: 10.1248/Cpb.42.2394 |
0.643 |
|
1994 |
Kobayashi M, Kurosu M, Ohyabu N, Wang W, Fujii S, Kitagawa I. The Absolute Stereostructure Of Arenastatin A, A Potent Cytotoxic Depsipeptide From The Okinawan Marine Sponge Dysidea Arenaria Chemical & Pharmaceutical Bulletin. 42: 2196-2198. DOI: 10.1248/Cpb.42.2196 |
0.65 |
|
1994 |
Kitagawa I, Simanjuntak P, Watano T, Shibuya H, Fujii S, Yamagata Y, Kobayashi M. Indonesian medicinal plants. XI: Chemical structures of caesaldekarins a and b, two new cassane-type furanoditerpenes from the roots of Caesalpinia major (Fabaceae) Chemical & Pharmaceutical Bulletin. 42: 1798-1802. DOI: 10.1248/Cpb.42.1798 |
0.651 |
|
1994 |
Kobayashi M, Aoki S, Kitagawa I. Absolute stereostructures of altohyrtin A and its congeners, potent cytotoxic macrolides from the Okinawan marine sponge hyrtios altum Tetrahedron Letters. 35: 1243-1246. DOI: 10.1016/0040-4039(94)88034-4 |
0.672 |
|
1994 |
Kobayashi M, Aoki S, Ohyabu N, Kurosu M, Wang W, Kitagawa I. Arenastatin A, a potent cytotoxic depsipeptide from the okinawan marine sponge Dysidea arenaria Tetrahedron Letters. 35: 7969-7972. DOI: 10.1016/0040-4039(94)80024-3 |
0.663 |
|
1993 |
Kobayashi M, Kondo K, Kitagawa I. Antifungal peroxyketal acids from an Okinawan marine sponge of Plakortis sp. Chemical & Pharmaceutical Bulletin. 41: 1324-6. PMID 8375002 DOI: 10.1248/Cpb.41.1324 |
0.596 |
|
1993 |
Kobayashi M, Aoki S, Sakai H, Kihara N, Sasaki T, Kitagawa I. Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum. Chemical & Pharmaceutical Bulletin. 41: 989-91. PMID 8339346 |
0.636 |
|
1993 |
Kobayashi M, Aoki S, Sakai H, Kawazoe K, Kihara N, Sasaki T, Kitagawa I. Altohyrtin A, a potent anti-tumor macrolide from the Okinawan marine sponge Hyrtios altum Tetrahedron Letters. 34: 2795-2798. DOI: 10.1016/S0040-4039(00)73564-7 |
0.647 |
|
1993 |
Kobayashi M, Uehara H, Matsunami K, Aoki S, Kitagawa I. Trichoharzin, a new polyketide produced by the imperfect fungus Trichoderma harzianum separated from the marine sponge Micale cecilia Tetrahedron Letters. 34: 7925-7928. DOI: 10.1016/S0040-4039(00)61513-7 |
0.631 |
|
1992 |
Ikegami S, Kajiyama N, Ozaki Y, Myotoishi Y, Miyashiro S, Takayama S, Kobayashi M, Kitagawa I. Selective inhibition of membrane fusion events in echinoderm gametes and embryos by halenaquinol sulfate. Febs Letters. 302: 284-6. PMID 1601136 DOI: 10.1016/0014-5793(92)80460-X |
0.538 |
|
1992 |
Kobayashi M, Kawazoe K, Katori T, Kitagawa I. Marine Natural Products. XXX. Two New 3-Keto-4-methylene Steroids, Theonellasterone and Conicasterone, and a Diels-Alder Type Dimeric Steroid Bistheonellasterone, from the Okinawan Marine Sponge Theonella swinhoei Chemical & Pharmaceutical Bulletin. 40: 1773-1778. DOI: 10.1248/Cpb.40.1773 |
0.615 |
|
1992 |
Kobayashi M, Hayashi K, Kawazoe K, Kitagawa I. Marine Natural Products. XXIX. Heterosigma-glycolipids I, II, III, and IV, Four Diacylglyceroglycolipids Possessing ω3-Polyunsaturated Fatty Acid Residues, from the Raphidopycean Dinoflagellate Heterosigma akashiwo Chemical & Pharmaceutical Bulletin. 40: 1404-1410. DOI: 10.1248/Cpb.40.1404 |
0.577 |
|
1991 |
Kobayashi M, Lee NK, Shibuya H, Momose T, Kitagawa I. Marine natural products. XXVI. Biologically active tridecapeptide lactones from the Okinawan marine sponge Theonella swinhoei (Theonellidae). (2). Structures of theonellapeptolides Ia, Ib, Ic, and Ie. Chemical & Pharmaceutical Bulletin. 39: 1177-84. PMID 1913995 DOI: 10.1248/Cpb.39.1177 |
0.578 |
|
1991 |
Kitagawa I, Kobayashi M. Anti-tumor Marine Natural Products Journal of Synthetic Organic Chemistry Japan. 49: 1053-1061. DOI: 10.5059/Yukigoseikyokaishi.49.1053 |
0.632 |
|
1991 |
Kobayashi M, Okamoto Y, Kitagawa I. Marine Natural Products. XXVIII. The Structures of Sarasinosides A1, A2, A3, B1, B2, B3, C1, C2, and C3, Nine New Norlanostane-Triterpenoidal Oligoglycosides from the Palauan Marine Sponge Asteropus sarasinosum Chemical & Pharmaceutical Bulletin. 39: 2867-2877. DOI: 10.1248/Cpb.39.2867 |
0.62 |
|
1991 |
KOBAYASHI M, HORI M, KAN K, YASUZAWA T, MATSUI M, SUZUKI S, KITAGAWA I. Marine Natural Products. XXVII. Distribution of Lanostane-Type Triterpene Oligoglycosides in Ten Kinds of Okinawan Sea Cucumbers. Chemical & Pharmaceutical Bulletin. 39: 2282-2287. DOI: 10.1248/Cpb.39.2282 |
0.638 |
|
1991 |
Doi M, Ishida T, Kobayashi M, Kitagawa I. Molecular conformation of swinholide A, a potent cytotoxic dimeric macrolide from the Okinawan marine sponge Theonella swinhoei: x-ray crystal structure of its diketone derivative Journal of Organic Chemistry. 56: 3629-3632. DOI: 10.1021/Jo00011A033 |
0.584 |
|
1991 |
Kitagawa I, Lee NK, Kobayashi M, Shibuya H. Marine natural products. XXV. Biologically active tridecapeptide lactones from the Okinawan marine sponge Theonella swinhoei (Theonellidae). Structure of theonellapeptolide Id Tetrahedron. 47: 2169-2180. DOI: 10.1016/S0040-4020(01)96128-9 |
0.628 |
|
1990 |
Kitagawa I, Kobayashi M. [Anti-tumor marine natural products]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 17: 322-9. PMID 2310201 |
0.573 |
|
1990 |
Kobayashi M, Tanaka J, Katori T, Kitagawa I. Marine natural products. XXIII. Three new cytotoxic dimeric macrolides, swinholides B and C and isoswinholide A, congeners of swinholide A, from the Okinawan marine sponge Theonella swinhoei. Chemical & Pharmaceutical Bulletin. 38: 2960-6. PMID 2085878 DOI: 10.1248/Cpb.38.2960 |
0.77 |
|
1990 |
TANAKA J, HIGA T, KOBAYASHI M, KITAGAWA I. Marine natural products. XXIV. The absolute stereostructure of misakinolide A, a potent cytotoxic dimeric macrolide from an Okinawan marine sponge Theonella sp. Chemical & Pharmaceutical Bulletin. 38: 2967-2970. DOI: 10.1248/Cpb.38.2967 |
0.809 |
|
1990 |
Kaneko F, Kobayashi M, Kitagawa Y, Matsuura Y. Structure of stearic acid E form Acta Crystallographica Section C Crystal Structure Communications. 46: 1490-1492. DOI: 10.1107/S0108270189012679 |
0.309 |
|
1990 |
Kitagawa I, Kobayashi M, Katori T, Yamashita M, Tanaka J, Doi M, Ishida T. Absolute stereostructure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge Theonella swinhoei Journal of the American Chemical Society. 112: 3710-3712. DOI: 10.1021/Ja00165A094 |
0.759 |
|
1989 |
Kobayashi M, Kawazoe K, Kitagawa I. Araguspongines B, C, D, E, F, G, H, and J, new vasodilative bis-1-oxaquinolizidine alkaloids from an okinawan marine sponge, Xestospongia sp. Chemical & Pharmaceutical Bulletin. 37: 1676-8. PMID 2776247 DOI: 10.1248/Cpb.37.1676 |
0.628 |
|
1989 |
Kitagawa I, Kobayashi M. [Anti-tumor natural products isolated from marine organisms]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 16: 1-8. PMID 2563218 |
0.585 |
|
1989 |
KITAGAWA I, HAYASHI K, KOBAYASHI M. Heterosigma-glycolipids I and II, two new galactolipids containing octadecatetraenoyl and eicosapentaenoyl residues, from a raphidophyte dinoflagellate Heterosigma sp. Chemical & Pharmaceutical Bulletin. 37: 849-851. DOI: 10.1248/Cpb.37.849 |
0.606 |
|
1989 |
KITAGAWA I, KOBAYASHI M, HORI M, KYOGOKU Y. Marine natural products. XVIII. Four lanostane-type triterpene oligoglycosides, bivittosides A, B, C, and D, from the Okinawan sea cucumber Bohadschia bivittata Mitsukuri. Chemical & Pharmaceutical Bulletin. 37: 61-67. DOI: 10.1248/Cpb.37.61 |
0.647 |
|
1989 |
KITAGAWA I, KOBAYASHI M, LEE NK, OYAMA Y, KYOGOKU Y. Marine natural products. XX. Bioactive scalarane-type bishomosesterterpenes from the okinawan marine sponge Phyllospongia foliascens. Chemical & Pharmaceutical Bulletin. 37: 2078-2082. DOI: 10.1248/Cpb.37.2078 |
0.671 |
|
1989 |
KITAGAWA I, KOBAYASHI M, SON BW, SUZUKI S, KYOGOKU Y. Marine natural products. XIX. Pervicosides A, B, and C, lanostane-type triterpene-oligoglycoside sulfates from the sea cucumber Holothuria pervicax. Chemical & Pharmaceutical Bulletin. 37: 1230-1234. DOI: 10.1248/Cpb.37.1230 |
0.636 |
|
1989 |
Kobayashi M, Kawazoe K, Kitagawa I. Aragupetrosine a, a new vasodilative macrocyclic quinolizidine alkaloid from an Okinawan marine sponge sp Tetrahedron Letters. 30: 4149-4152. DOI: 10.1016/S0040-4039(00)99345-6 |
0.629 |
|
1989 |
Kobayashi M, Tanaka Ji, Katori T, Matsuura M, Kitagawa I. Structure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge Theonella Swinhoei Tetrahedron Letters. 30: 2963-2966. DOI: 10.1016/S0040-4039(00)99170-6 |
0.767 |
|
1987 |
Kitagawa I, Lee NK, Kobayashi M, Shibuya H. Structure of theonellapeptolide Ie, a new tridecapeptide lactone from an Okinawan marine sponge, Theonella sp. (Theonellidae). Chemical & Pharmaceutical Bulletin. 35: 2129-32. PMID 3664821 DOI: 10.1248/Cpb.35.2129 |
0.635 |
|
1987 |
Kitagawa I, Kobayashi M, Okamoto Y, Yoshikawa M, Hamamoto Y. Structures of sarasinosides A1, B1, and C1; new norlanostane-triterpenoid oligoglycosides from the Palauan marine sponge Asteropus sarasinosum. Chemical & Pharmaceutical Bulletin. 35: 5036-9. PMID 3451822 DOI: 10.1248/Cpb.35.5036 |
0.657 |
|
1987 |
Kitagawa I, Cui Z, Son BW, Kobayashi M, Kyogoku Y. Marine natural products. XVII. Nephtheoxydiol, a new cytotoxic hydroperoxy-germacrane sesquiterpene, and related sesquiterpenoids from an Okinawan soft coral of Nephthea sp. (Nephtheidae). Chemical & Pharmaceutical Bulletin. 35: 124-35. PMID 2885097 DOI: 10.1248/Cpb.35.124 |
0.592 |
|
1986 |
Kobayashi M, Son BW, Kyogoku Y, Kitagawa I. Kericembrenolides A, B, C, D, and E, five new cytotoxic cembrenolides from the Okinawan soft coral Clavularia koellikeri. Chemical & Pharmaceutical Bulletin. 34: 2306-9. PMID 3742667 DOI: 10.1248/Cpb.34.2306 |
0.642 |
|
1986 |
KITAGAWA I, ZHENG C, CAI Y, KOBAYASHI M, KYOGOKU Y. Marine natural products. XVI Structures of five new diterpenes from an Okinawan soft coral of Xenia sp. (Xeniidae). Chemical & Pharmaceutical Bulletin. 34: 4641-4652. DOI: 10.1248/Cpb.34.4641 |
0.634 |
|
1986 |
KITAGAWA I, KOBAYASHI M, ZHENG C, KIYOTA Y, OHNISHI M. Marine natural products. XV Chemical constituents of an Okinawan soft coral of Xenia sp. (Xeniidae). Chemical & Pharmaceutical Bulletin. 34: 4590-4596. DOI: 10.1248/Cpb.34.4590 |
0.597 |
|
1986 |
Kitagawa I, Kobayashi M, Lee NK, Shibuya H, Kawata Y, Sakiyama F. Structure of theonellapeptolide Id, a new bioactive peptolide from an Okinawan marine sponge, Theonella sp. (Theonelliae). Chemical & Pharmaceutical Bulletin. 34: 2664-2667. DOI: 10.1248/Cpb.34.2664 |
0.659 |
|
1985 |
Kitagawa I, Kobayashi M, Inamoto T, Fuchida M, Kyogoku Y. Marine natural products. XIV. Structures of echinosides A and B, antifungal lanostane-oligosides from the sea cucumber Actinopyga echinites (Jaeger). Chemical & Pharmaceutical Bulletin. 33: 5214-24. PMID 3833380 DOI: 10.1248/Cpb.33.5214 |
0.597 |
|
1985 |
Kobayashi M, Zheng C, Yang C, Kyogoku Y, Kitagawa I. Xeniolone and isoxeniolone. Two new diterpenes having a perhydroazulene skeleton from an Okinawan soft coral of Xenia sp. Chemical & Pharmaceutical Bulletin. 33: 1309-1312. DOI: 10.1248/Cpb.33.1309 |
0.634 |
|
1985 |
Kobayashi M, Shimizu N, Kyogoku Y, Kitagawa I. Halenaquinol and halenaquinol sulfate, pentacyclic hydroquinones from the Okinawan marine sponge Xestospongia sapra. Chemical & Pharmaceutical Bulletin. 33: 1305-1308. DOI: 10.1248/Cpb.33.1305 |
0.643 |
|
1985 |
Kobayashi M, Shimizu N, Kitagawa I, Kyogoku Y, Harada N, Uda H. Absolute stereostructures of halenaquinol and halenaquinol sulfate, pentacyclic hydroquinones from the okinawan marine sponge xestospongia sapra, as determined by theoretical calculation of CD spectra Tetrahedron Letters. 26: 3833-3836. DOI: 10.1016/S0040-4039(00)89263-1 |
0.55 |
|
1985 |
Kitagawa I, Kobayashi M, Yasuzawa T, Son BW, Yoshihara M, Kyogoku Y. New prostanoids from soft coral Tetrahedron. 41: 995-1005. DOI: 10.1016/S0040-4020(01)96467-1 |
0.659 |
|
1984 |
Nishihata T, Kato J, Kim KH, Kobayashi M, Kitagawa I, Kamada A. Formation and hydrolysis of enamine in aqueous solution. Chemical & Pharmaceutical Bulletin. 32: 4545-50. PMID 6442627 DOI: 10.1248/Cpb.32.4545 |
0.533 |
|
1984 |
Kobayashi M, Son BW, Kyogoku Y, Kitagawa I. Clavukerin C, a new trinor-guaiane sesquiterpene having a hydroperoxy function, from the Okinawan soft coral Clavularia koellikeri. Chemical & Pharmaceutical Bulletin. 32: 1667-1670. DOI: 10.1248/Cpb.32.1667 |
0.647 |
|
1984 |
Kobayashi M, Lee NK, Son BW, Yanag K, Kyogoku Y, Kitagawa I. Stoloniferone-a, -b, -c, and -d, four new cytotoxic steroids from the okinawan soft coral clavularia viridis Tetrahedron Letters. 25: 5925-5928. DOI: 10.1016/S0040-4039(01)81722-6 |
0.644 |
|
1984 |
Kobayashi M, Wha Son B, Fujiwara T, Kyogoku Y, Kitagawa I. Neodolabelline, a methyl migrated dolabellane-type diterpene from the okinawan soft coral clavularia koellikeri Tetrahedron Letters. 25: 5543-5546. DOI: 10.1016/S0040-4039(01)81621-X |
0.599 |
|
1984 |
Kobayashi M, Kiyota Y, Orito S, Kyogoku Y, Kitagawa I. Five new steroidal glycosides, pregnedioside-A, -B, and their three monoacetates, from an Okinawan soft coral of Alcyonium sp Tetrahedron Letters. 25: 3731-3734. DOI: 10.1016/0040-4039(84)80117-3 |
0.634 |
|
1983 |
KIKUCHI H, TSUKITANI Y, SHIMIZU I, KOBAYASHI M, KITAGAWA I. Marine natural products. XI. An antiinflammatory scalarane-type bishomosesterterpene, foliaspongin, from the Okinawan marine sponge Phyllospongia foliascens (Pallas). Chemical & Pharmaceutical Bulletin. 31: 552-556. DOI: 10.1248/Cpb.31.552 |
0.639 |
|
1983 |
KITAGAWA I, KOBAYASHI M, KITANAKA K, KIDO M, KYOGOKU Y. Marine natural products. XII. On the chemical constituents of the Okinawan marine sponge Hymeniacidon aldis. Chemical & Pharmaceutical Bulletin. 31: 2321-2328. DOI: 10.1248/Cpb.31.2321 |
0.607 |
|
1983 |
Kobayashi M, Son B, Kido M, Kyogoku Y, Kitagawa I. Clavukerin A, a new trinor-guaiane sesquiterpene from the okinawan soft coral Clavularia koellikeri. Chemical & Pharmaceutical Bulletin. 31: 2160-2163. DOI: 10.1248/Cpb.31.2160 |
0.611 |
|
1983 |
Kobayashi M, Yasuzawa T, Yoshihara M, Son B, Kyogoku Y, Kitagawa I. Absolute stereostructures of claviridenone-A, -B, -C, and -D four prostanoids from the Okinawan soft coral Clavularia viridis. Chemical & Pharmaceutical Bulletin. 31: 1440-1443. DOI: 10.1248/Cpb.31.1440 |
0.633 |
|
1982 |
KIKUCHI H, TSUKITANI Y, MANDA T, FUJII T, NAKANISHI H, KOBAYASHI M, KITAGAWA I. Marine natural products. X. Pharmacologically active glycolipids from the okinawan marine sponge Phyllospongia foliascens (Pallas). Chemical & Pharmaceutical Bulletin. 30: 3544-3547. DOI: 10.1248/Cpb.30.3544 |
0.592 |
|
1982 |
Kobayashi M, Yasuzawa T, Kyogoku Y, Kido M, Kitagawa I. Three new ent-valerenane sesquiterpenes from an okinawan soft coral. Chemical & Pharmaceutical Bulletin. 30: 3431-3434. DOI: 10.1248/Cpb.30.3431 |
0.619 |
|
1982 |
KITAGAWA I, KOBAYASHI M, KYOGOKU Y. Marine natural products. IX. Structural elucidation of triterpenoidal oligoglycosides from the Bahamean sea cucumber Actinopyga agassizi Selenka. Chemical & Pharmaceutical Bulletin. 30: 2045-2050. DOI: 10.1248/Cpb.30.2045 |
0.649 |
|
1982 |
Kobayashi M, Yasuzawa T, Yoshihara M, Akutsu H, Kyogoku Y, Kitagawa I. Four new prostanoids: Claviridenone-A, -B, -C, and -D from the okinawan soft coral Tetrahedron Letters. 23: 5331-5334. DOI: 10.1016/S0040-4039(00)85831-1 |
0.652 |
|
1981 |
KITAGAWA I, KOBAYASHI M, HORI M, KYOGOKU Y. Structures of four new triterpenoidal oligoglycosides, bivittoside A,B,C, and D, from the sea cucumber Bohadschia bivittata Mitsukuri. Chemical & Pharmaceutical Bulletin. 29: 282-285. DOI: 10.1248/Cpb.29.282 |
0.672 |
|
1981 |
KITAGAWA I, KOBAYASHI M, INAMOTO T, YASUZAWA T, KYOGOKU Y. The structures of six antifungal oligoglycosides, stichlorosides A1,A2,B1,B2,C1, and C2, from the sea cucumber Stichopus chloronotus (Brandt). Chemical & Pharmaceutical Bulletin. 29: 2387-2391. DOI: 10.1248/Cpb.29.2387 |
0.623 |
|
1981 |
KITAGAWA I, NISHINO T, KOBAYASHI M, MATSUNO T, AKUTSU H, KYOGOKU Y. Marine natural products. VII. Bioactive triterpene-oligoglycosides from the sea cucumber Holothuria leucospilota Brandt (1). Structure of holothurin B. Chemical & Pharmaceutical Bulletin. 29: 1942-1950. DOI: 10.1248/Cpb.29.1942 |
0.645 |
|
1981 |
KIKUCHI H, TSUKITANI Y, SHIMIZU I, KOBAYASHI M, KITAGAWA I. Foliaspongin, an antiinflammatory bishomosesterterpene from the marine sponge Phyllospongia foliascens (Pallas). Chemical & Pharmaceutical Bulletin. 29: 1492-1494. DOI: 10.1248/Cpb.29.1492 |
0.65 |
|
1981 |
KITAGAWA I, KOBAYASHI M, INAMOTO T, YASUZAWA T, KYOGOKU Y, KIDO M. Stichlorogenol and dehydrostichlorogenol,genuine aglycones of stichlorosides A1,B1,C1 and A2,B2,C2,from the sea cucumber Stichopus chloronotus (Brandt). Chemical & Pharmaceutical Bulletin. 29: 1189-1192. DOI: 10.1248/Cpb.29.1189 |
0.621 |
|
1981 |
Kobayashi M, Yasuzawa T, Kobayashi Y, Kyogoku Y, Kitagawa I. Alcyonolide, a novel diterpenoid from a soft coral Tetrahedron Letters. 22: 4445-4448. DOI: 10.1016/S0040-4039(01)82979-8 |
0.641 |
|
1980 |
KITAGAWA I, INAMOTO T, FUCHIDA M, OKADA S, KOBAYASHI M, NISHINO T, KYOGOKU Y. Structures of echinoside A and B, two antifungal oligoglycosides from the sea cucumber Actinopyga echinites (Jaeger). Chemical & Pharmaceutical Bulletin. 28: 1651-1653. DOI: 10.1248/Cpb.28.1651 |
0.642 |
|
1979 |
Kitagawa I, Hamamoto Y, Kobayashi M. Sulfonoglycolipid from the sea urchin Anthocidaris crassispina A. Agassiz. Chemical & Pharmaceutical Bulletin. 27: 1394-7. PMID 540352 DOI: 10.1248/Cpb.27.1934 |
0.597 |
|
1978 |
KITAGAWA I, YAMANAKA H, KOBAYASHI M, NISHINO T, YOSIOKA I, SUGAWARA T. Saponin and sapogenol. XXVII. Revised structures of holotoxin A and holotoxin B, two antifungal oligoglycosides from the sea cucumber Stichopus japonicus Selenka. Chemical & Pharmaceutical Bulletin. 26: 3722-3731. DOI: 10.1248/Cpb.26.3722 |
0.588 |
|
1978 |
KITAGAWA I, KOBAYASHI M. Saponin and sapogenol. XXVI. Steroidal saponins from the starfish Acanthaster planci L. (crown of thorns). 2. Structure of the major saponin thornasteroside A. Chemical & Pharmaceutical Bulletin. 26: 1864-1873. DOI: 10.1248/Cpb.26.1864 |
0.591 |
|
1978 |
KITAGAWA I, KOBAYASHI M, SUGAWARA T. Saponin and sapogenol. XXV. Steroidal saponins from the starfish Acanthaster planci L. (crown of thorns). 1. Structures of two genuine sapogenols, thornasterol A and thornasterol B, and their sulfates. Chemical & Pharmaceutical Bulletin. 26: 1852-1863. DOI: 10.1248/Cpb.26.1852 |
0.603 |
|
1977 |
Kitagawa I, Kobayashi M. On the structure of the major saponin from the starfish acanthaster planci Tetrahedron Letters. 18: 859-862. DOI: 10.1016/S0040-4039(01)92775-3 |
0.601 |
|
1975 |
Kitagawa I, Kobayashi M, Sugawara T, Yosioka I. Thornasterol A and B, two genuine sapogenols from the starfish acanthaster planci Tetrahedron Letters. 16: 967-970. DOI: 10.1016/S0040-4039(00)72032-6 |
0.581 |
|
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