Motomasa Kobayashi, Ph.D. - Publications

Affiliations: 
Pharmaceutical Sciences Osaka University, Toyonaka-shi, Ōsaka-fu, Japan 
Area:
Natural Products Drug Discovery, Synthesis

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kawachi T, Tanaka S, Fukuda A, Sumii Y, Setiawan A, Kotoku N, Kobayashi M, Arai M. Target Identification of the Marine Natural Products Dictyoceratin-A and -C as Selective Growth Inhibitors in Cancer Cells Adapted to Hypoxic Environments. Marine Drugs. 17. PMID 30857246 DOI: 10.3390/Md17030163  0.668
2018 Ishida R, Matsumoto H, Ichii S, Kobayashi M, Arai M, Kotoku N. Structure-Activity Relationship of Biakamide, Selective Growth Inhibitors under Nutrient-starved Condition from Marine Sponge. Chemical & Pharmaceutical Bulletin. PMID 30429430 DOI: 10.1248/Cpb.C18-00587  0.363
2017 Kamiya K, Arai M, Setiawan A, Kobayashi M. Anti-dormant Mycobacterial Activity of Viomellein and Xanthomegnin, Naphthoquinone Dimers Produced by Marine- derived Aspergillus sp. Natural Product Communications. 12: 579-581. PMID 30520600 DOI: 10.1177/1934578X1701200428  0.351
2017 Kotoku N, Ishida R, Matsumoto H, Arai M, Toda K, Setiawan A, Muraoka O, Kobayashi M. Biakamides A-D, unique polyketides from a marine sponge, act as selective growth inhibitors of tumor cells adapted to nutrient starvation. The Journal of Organic Chemistry. PMID 28090774 DOI: 10.1021/Acs.Joc.6B02948  0.374
2017 Kotoku N, Ito A, Shibuya S, Mizuno K, Takeshima A, Nogata M, Kobayashi M. Short-step synthesis and structure-activity relationship of cortistatin A analogs Tetrahedron. 73: 1342-1349. DOI: 10.1016/J.Tet.2017.01.042  0.361
2016 Arai M, Shin D, Kamiya K, Ishida R, Setiawan A, Kotoku N, Kobayashi M. Marine spongean polybrominated diphenyl ethers, selective growth inhibitors against the cancer cells adapted to glucose starvation, inhibits mitochondrial complex II. Journal of Natural Medicines. PMID 27449332 DOI: 10.1007/S11418-016-1025-X  0.325
2016 Arai M, Kamiya K, Shin D, Matsumoto H, Hisa T, Setiawan A, Kotoku N, Kobayashi M. N-Methylniphatyne A, a New 3-Alkylpyridine Alkaloid as an Inhibitor of the Cancer Cells Adapted to Nutrient Starvation, from an Indonesian Marine Sponge of Xestospongia sp. Chemical & Pharmaceutical Bulletin. 64: 766-71. PMID 27373630 DOI: 10.1248/Cpb.C16-00118  0.392
2016 Kotoku N, Arai M, Kobayashi M. Search for Anti-angiogenic Substances from Natural Sources. Chemical & Pharmaceutical Bulletin. 64: 128-34. PMID 26833441 DOI: 10.1248/Cpb.C15-00744  0.305
2015 Sumii Y, Kotoku N, Fukuda A, Kawachi T, Arai M, Kobayashi M. Structure-Activity Relationship and in Vivo Anti-Tumor Evaluations of Dictyoceratin-A and -C, Hypoxia-Selective Growth Inhibitors from Marine Sponge. Marine Drugs. 13: 7419-32. PMID 26694423 DOI: 10.3390/Md13127074  0.705
2015 Arai M, Kamiya K, Pruksakorn P, Sumii Y, Kotoku N, Joubert JP, Moodley P, Han C, Shin D, Kobayashi M. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorganic & Medicinal Chemistry. 23: 3534-41. PMID 25934225 DOI: 10.1016/J.Bmc.2015.04.033  0.692
2015 Sumii Y, Kotoku N, Fukuda A, Kawachi T, Sumii Y, Arai M, Kobayashi M. Enantioselective synthesis of dictyoceratin-A (smenospondiol) and -C, hypoxia-selective growth inhibitors from marine sponge. Bioorganic & Medicinal Chemistry. 23: 966-75. PMID 25659617 DOI: 10.1016/J.Bmc.2015.01.021  0.68
2014 Kotoku N, Higashimoto K, Kurioka M, Arai M, Fukuda A, Sumii Y, Sowa Y, Sakai T, Kobayashi M. Xylarianaphthol-1, a novel dinaphthofuran derivative, activates p21 promoter in a p53-independent manner. Bioorganic & Medicinal Chemistry Letters. 24: 3389-91. PMID 24939757 DOI: 10.1016/J.Bmcl.2014.05.083  0.662
2014 Arai M, Kawachi T, Sato H, Setiawan A, Kobayashi M. Marine spongian sesquiterpene phenols, dictyoceratin-C and smenospondiol, display hypoxia-selective growth inhibition against cancer cells. Bioorganic & Medicinal Chemistry Letters. 24: 3155-7. PMID 24865416 DOI: 10.1016/J.Bmcl.2014.04.116  0.357
2014 Kotoku N, Nakata C, Kawachi T, Sato T, Guo XH, Ito A, Sumii Y, Arai M, Kobayashi M. Synthesis and evaluation of effective photoaffinity probe molecule of furospinosulin-1, a hypoxia-selective growth inhibitor. Bioorganic & Medicinal Chemistry. 22: 2102-12. PMID 24631363 DOI: 10.1016/J.Bmc.2014.02.026  0.652
2014 Arai M, Han C, Yamano Y, Setiawan A, Kobayashi M. Aaptamines, marine spongean alkaloids, as anti-dormant mycobacterial substances. Journal of Natural Medicines. 68: 372-6. PMID 24414399 DOI: 10.1007/S11418-013-0811-Y  0.405
2014 Arai M, Yamano Y, Setiawan A, Kobayashi M. Identification of the target protein of agelasine D, a marine sponge diterpene alkaloid, as an anti-dormant mycobacterial substance. Chembiochem : a European Journal of Chemical Biology. 15: 117-23. PMID 24243718 DOI: 10.1002/Cbic.201300470  0.318
2013 Kotoku N, Mizushima K, Tamura S, Kobayashi M. Synthetic studies of cortistatin A analogue from the CD-ring fragment of vitamin D₂. Chemical & Pharmaceutical Bulletin. 61: 1024-9. PMID 24088693 DOI: 10.1248/Cpb.C13-00375  0.304
2012 Kotoku N, Sumii Y, Hayashi T, Tamura S, Kawachi T, Shiomura S, Arai M, Kobayashi M. Creation of readily accessible and orally active analogue of cortistatin a. Acs Medicinal Chemistry Letters. 3: 673-7. PMID 24900528 DOI: 10.1021/Ml300143D  0.699
2012 Yamano Y, Arai M, Kobayashi M. Neamphamide B, new cyclic depsipeptide, as an anti-dormant mycobacterial substance from a Japanese marine sponge of Neamphius sp. Bioorganic & Medicinal Chemistry Letters. 22: 4877-81. PMID 22704240 DOI: 10.1016/J.Bmcl.2012.05.071  0.402
2012 Arai M, Yamano Y, Fujita M, Setiawan A, Kobayashi M. Stylissamide X, a new proline-rich cyclic octapeptide as an inhibitor of cell migration, from an Indonesian marine sponge of Stylissa sp. Bioorganic & Medicinal Chemistry Letters. 22: 1818-21. PMID 22260773 DOI: 10.1016/J.Bmcl.2011.10.023  0.371
2011 Pruksakorn P, Arai M, Liu L, Moodley P, Jacobs WR, Kobayashi M. Action-mechanism of trichoderin A, an anti-dormant mycobacterial aminolipopeptide from marine sponge-derived Trichoderma sp. Biological & Pharmaceutical Bulletin. 34: 1287-90. PMID 21804219 DOI: 10.1248/Bpb.34.1287  0.332
2011 Kotoku N, Sumii Y, Kobayashi M. Stereoselective synthesis of core structure of cortistatin A. Organic Letters. 13: 3514-7. PMID 21651309 DOI: 10.1021/Ol201327U  0.684
2011 Kong D, Yamori T, Kobayashi M, Duan H. Antiproliferative and antiangiogenic activities of smenospongine, a marine sponge sesquiterpene aminoquinone. Marine Drugs. 9: 154-61. PMID 21566792 DOI: 10.3390/Md9020154  0.303
2011 Arai M, Hayashi A, Sobou M, Ishida S, Kawachi T, Kotoku N, Kobayashi M. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. Journal of Natural Medicines. 65: 149-56. PMID 21042868 DOI: 10.1007/S11418-010-0477-7  0.316
2011 Kotoku N, Sumii Y, Hayashi T, Kobayashi M. Synthetic study of carbocyclic core of cortistatin a, an anti-angiogenic steroidal alkaloid from marine sponge Heterocycles. 83: 1535-1552. DOI: 10.3987/Com-11-12195  0.668
2011 Kotoku N, Fujioka S, Nakata C, Yamada M, Sumii Y, Kawachi T, Arai M, Kobayashi M. Concise synthesis and structure-activity relationship of furospinosulin-1, a hypoxia-selective growth inhibitor from marine sponge Tetrahedron. 67: 6673-6678. DOI: 10.1016/J.Tet.2011.05.009  0.69
2010 Arai M, Kawachi T, Setiawan A, Kobayashi M. Hypoxia-selective growth inhibition of cancer cells by furospinosulin-1, a furanosesterterpene isolated from an Indonesian marine sponge. Chemmedchem. 5: 1919-26. PMID 20839272 DOI: 10.1002/Cmdc.201000302  0.307
2010 Pruksakorn P, Arai M, Kotoku N, Vilchèze C, Baughn AD, Moodley P, Jacobs WR, Kobayashi M. Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria. Bioorganic & Medicinal Chemistry Letters. 20: 3658-63. PMID 20483615 DOI: 10.1016/J.Bmcl.2010.04.100  0.41
2009 Arai M, Ishida S, Setiawan A, Kobayashi M. Haliclonacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Haliclona sp. Chemical & Pharmaceutical Bulletin. 57: 1136-8. PMID 19801875 DOI: 10.1248/Cpb.57.1136  0.41
2009 Hayashi A, Arai M, Fujita M, Kobayashi M. Pyripyropenes, fungal sesquiterpenes conjugated with alpha-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells. Biological & Pharmaceutical Bulletin. 32: 1261-5. PMID 19571395 DOI: 10.1248/Bpb.32.1261  0.346
2009 Suna H, Arai M, Tsubotani Y, Hayashi A, Setiawan A, Kobayashi M. Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. Bioorganic & Medicinal Chemistry. 17: 3968-72. PMID 19414266 DOI: 10.1016/J.Bmc.2009.04.025  0.303
2009 Tamura S, Shiomi A, Kaneko M, Ye Y, Yoshida M, Yoshikawa M, Kimura T, Kobayashi M, Murakami N. New Rev-export inhibitor from Alpinia galanga and structure-activity relationship. Bioorganic & Medicinal Chemistry Letters. 19: 2555-7. PMID 19342232 DOI: 10.1016/J.Bmcl.2009.03.047  0.317
2008 Kotoku N, Hiramatsu A, Tsujita H, Hirakawa Y, Sanagawa M, Aoki S, Kobayashi M. Structure-activity relationships study of bastadin 6, an anti-angiogenic brominated-tyrosine derived metabolite from marine sponge. Archiv Der Pharmazie. 341: 568-77. PMID 18763716 DOI: 10.1002/Ardp.200700231  0.355
2008 Kotoku N, Tamada N, Hayashi A, Kobayashi M. Synthesis of BC-ring model of globostellatic acid X methyl ester, an anti-angiogenic substance from marine sponge. Bioorganic & Medicinal Chemistry Letters. 18: 3532-5. PMID 18492609 DOI: 10.1016/J.Bmcl.2008.05.018  0.322
2008 Kotoku N, Sumii Y, Hayashi T, Kobayashi M. Synthesis of CD-ring structure of cortistatin A, an anti-angiogenic steroidal alkaloid from marine sponge Tetrahedron Letters. 49: 7078-7081. DOI: 10.1016/J.Tetlet.2008.09.157  0.662
2007 Wei H, Inada H, Hayashi A, Higashimoto K, Pruksakorn P, Kamada S, Arai M, Ishida S, Kobayashi M. Prenylterphenyllin and its dehydroxyl analogs, new cytotoxic substances from a marine-derived Fungus Aspergillus candidus IF10. The Journal of Antibiotics. 60: 586-90. PMID 17917243 DOI: 10.1038/Ja.2007.75  0.43
2007 Aoki S, Watanabe Y, Tanabe D, Arai M, Suna H, Miyamoto K, Tsujibo H, Tsujikawa K, Yamamoto H, Kobayashi M. Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids. Bioorganic & Medicinal Chemistry. 15: 6758-62. PMID 17765550 DOI: 10.1016/J.Bmc.2007.08.017  0.353
2007 Aoki S, Sanagawa M, Watanabe Y, Setiawan A, Arai M, Kobayashi M. Novel isomarabarican triterpenes, exhibiting selective anti-proliferative activity against vascular endothelial cells, from marine sponge Rhabdastrella globostellata. Bioorganic & Medicinal Chemistry. 15: 4818-28. PMID 17524651 DOI: 10.1016/J.Bmc.2007.04.070  0.353
2007 Kotoku N, Narumi F, Kato T, Yamaguchi M, Kobayashi M. Stereoselective total synthesis of arenastatin A, a spongean cytotoxic depsipeptide Tetrahedron Letters. 48: 7147-7150. DOI: 10.1016/J.Tetlet.2007.07.193  0.309
2007 Aoki S, Watanabe Y, Tanabe D, Setiawan A, Arai M, Kobayashi M. Cortistatins J, K, L, novel abeo-9(10-19)-androstane-type steroidal alkaloids with isoquinoline unit, from marine sponge Corticium simplex Tetrahedron Letters. 48: 4485-4488. DOI: 10.1016/J.Tetlet.2007.05.003  0.332
2007 Watanabe Y, Aoki S, Tanabe D, Setiawan A, Kobayashi M. Cortistatins E, F, G, and H, four novel steroidal alkaloids from marine sponge Corticium simplex Tetrahedron. 63: 4074-4079. DOI: 10.1016/J.Tet.2007.02.112  0.386
2006 Aoki S, Cho SH, Hiramatsu A, Kotoku N, Kobayashi M. Bastadins, cyclic tetramers of brominated-tyrosine derivatives, selectively inhibit the proliferation of endothelial cells. Journal of Natural Medicines. 60: 231-235. PMID 29435890 DOI: 10.1007/S11418-006-0045-3  0.369
2006 Aoki S, Watanabe Y, Sanagawa M, Setiawan A, Kotoku N, Kobayashi M. Cortistatins A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex. Journal of the American Chemical Society. 128: 3148-9. PMID 16522087 DOI: 10.1021/Ja057404H  0.402
2006 Wei H, Itoh T, Kotoku N, Kobayashi M. Shimalactones, neuritogenic polyketides from A marine-derived fungus Emericella variecolor GF10 Heterocycles. 68: 111-123. DOI: 10.3987/Com-05-10589  0.421
2005 Wei H, Itoh T, Kinoshita M, Kotoku N, Aoki S, Kobayashi M. Shimalactone A, a novel polyketide, from marine-derived fungus Emericella variecolor GF10 Tetrahedron. 61: 8054-8058. DOI: 10.1016/J.Tet.2005.05.105  0.387
2004 Kawanishi M, Kotoku N, Itagaki S, Horii T, Kobayashi M. Structure-activity relationship of anti-malarial spongean peroxides having a 3-methoxy-1,2-dioxane structure. Bioorganic & Medicinal Chemistry. 12: 5297-307. PMID 15388157 DOI: 10.1016/J.Bmc.2004.04.051  0.322
2004 Aoki S, Kong D, Matsui K, Rachmat R, Kobayashi M. Sesquiterpene aminoquinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells. Chemical & Pharmaceutical Bulletin. 52: 935-7. PMID 15304984 DOI: 10.1248/Cpb.52.935  0.317
2004 Murakami N, Tamura S, Koyama K, Sugimoto M, Maekawa R, Kobayashi M. New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity. Bioorganic & Medicinal Chemistry Letters. 14: 2597-601. PMID 15109660 DOI: 10.1016/J.Bmcl.2004.02.080  0.349
2004 Wei H, Itoh T, Kinoshita M, Nakai Y, Kurotaki M, Kobayashi M. Cytotoxic sesterterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF10 Tetrahedron. 60: 6015-6019. DOI: 10.1016/J.Tet.2004.05.021  0.389
2004 Aoki S, Cao L, Matsui K, Rachmat R, Akiyama SI, Kobayashi M. Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp Tetrahedron. 60: 7053-7059. DOI: 10.1016/J.Tet.2003.07.020  0.341
2003 Itoh T, Kinoshita M, Wei H, Kobayashi M. Stereostructure of komodoquinone A, a neuritogenic anthracycline, from marine Streptomyces sp. KS3. Chemical & Pharmaceutical Bulletin. 51: 1402-4. PMID 14646317 DOI: 10.1248/Cpb.51.1402  0.353
2003 Murakami N, Kawanishi M, Mostaqul HM, Li J, Itagaki S, Horii T, Kobayashi M. New anti-malarial peroxides with in vivo potency derived from spongean metabolites. Bioorganic & Medicinal Chemistry Letters. 13: 4081-4. PMID 14592512 DOI: 10.1016/J.Bmcl.2003.08.073  0.337
2003 Itoh T, Kinoshita M, Aoki S, Kobayashi M. Komodoquinone A, a novel neuritogenic anthracycline, from marine Streptomyces sp. KS3. Journal of Natural Products. 66: 1373-7. PMID 14575440 DOI: 10.1021/Np030212K  0.415
2003 Ohta E, Okada H, Ohta S, Kobayashi M, Kitagawa I, Horiike S, Takahashi T, Hosoya H, Yamamoto K, Ikegami S. Malformation of immature starfish oocytes by theonellapeptolide Ie, a tridecapeptide lactone from a marine sponge Petrosia species, through disturbance of cortical F-actin distribution Bioscience, Biotechnology and Biochemistry. 67: 1908-1915. PMID 14519975 DOI: 10.1271/Bbb.67.1908  0.565
2003 Aoki S, Wei H, Matsui K, Rachmat R, Kobayashi M. Pyridoacridine alkaloids inducing neuronal differentiation in a neuroblastoma cell line, from marine sponge Biemna fortis. Bioorganic & Medicinal Chemistry. 11: 1969-73. PMID 12670647 DOI: 10.1016/S0968-0896(03)00086-5  0.341
2002 Aoki S, Naka Y, Itoh T, Furukawa T, Rachmat R, Akiyama S, Kobayashi M. Lembehsterols A and B, novel sulfated sterols inhibiting thymidine phosphorylase, from the marine sponge Petrosia strongylata. Chemical & Pharmaceutical Bulletin. 50: 827-30. PMID 12045340 DOI: 10.1248/Cpb.50.827  0.411
2002 Murakami N, Kawanishi M, Itagaki S, Horii T, Kobayashi M. New readily accessible peroxides with high anti-malarial potency. Bioorganic & Medicinal Chemistry Letters. 12: 69-72. PMID 11738575 DOI: 10.1016/S0960-894X(01)00673-4  0.339
2002 Aoki S, Matsui K, Wei H, Murakami N, Kobayashi M. Structure-activity relationship of neuritogenic spongean acetylene alcohols, lembehynes Tetrahedron. 58: 5417-5422. DOI: 10.1016/S0040-4020(02)00519-7  0.34
2001 Aoki S, Ye Y, Higuchi K, Takashima A, Tanaka Y, Kitagawa I, Kobayashi M. Novel neuronal nitric oxide synthase (nNOS) selective inhibitor, aplysinopsin-type indole alkaloid, from marine sponge Hyrtios erecta Chemical and Pharmaceutical Bulletin. 49: 1372-1374. PMID 11605676 DOI: 10.1248/Cpb.49.1372  0.636
2001 Murakami N, Mostaqul HM, Tamura S, Itagaki S, Horii T, Kobayashi M. New anti-malarial flavonol glycoside from Hydrangeae Dulcis Folium Bioorganic and Medicinal Chemistry Letters. 11: 2445-2447. PMID 11549443 DOI: 10.1016/S0960-894X(01)00467-X  0.359
2001 Murakami N, Sugimoto M, Nakajima T, Kawanishi M, Tsutsui Y, Kobayashi M. Participation of the conjugated diene part for potent cytotoxicity of callystatin A, a spongean polyketide. Bioorganic & Medicinal Chemistry. 8: 2651-61. PMID 11092550 DOI: 10.1016/S0968-0896(00)00199-1  0.389
2001 Murakami N, Wang W, Tamura S, Kobayashi M. Synthesis and biological property of carba and 20-deoxo analogues of arenastatin A. Bioorganic & Medicinal Chemistry Letters. 10: 1823-6. PMID 10969977 DOI: 10.1016/S0960-894X(00)00356-5  0.315
2001 Murakami N, Kawanishi M, Itagaki S, Horii T, Kobayashi M. Facile construction of 6-carbomethoxymethyl-3-methoxy-1,2-dioxane, a core structure of spongean anti-malarial peroxides Tetrahedron Letters. 42: 7281-7285. DOI: 10.1016/S0040-4039(01)01493-9  0.301
2001 Aoki S, Okano M, Matsui K, Itoh T, Satari R, Akiyama SI, Kobayashi M. Brianthein A, a novel briarane-type diterpene reversing multidrug resistance in human carcinoma cell line, from the gorgonian Briareum excavatum Tetrahedron. 57: 8951-8957. DOI: 10.1016/S0040-4020(01)00894-8  0.382
2001 Murakami N, Tamura S, Wang W, Takagi T, Kobayashi M. Synthesis of stable analogs in blood and conformational analysis of arenastatin A, a potent cytotoxic spongean depsipeptide Tetrahedron. 57: 4323-4336. DOI: 10.1016/S0040-4020(01)00339-8  0.308
2001 Aoki S, Nemoto N, Kobayashi Y, Kobayashi M, Kitagawa I. Molecular modeling of 5-desacetylaltohyrtin A, a spongean cytotoxic macrolide Tetrahedron. 57: 2289-2292. DOI: 10.1016/S0040-4020(01)00111-9  0.608
2000 Aoki S, Matsui K, Tanaka K, Satari R, Kobayashi M. Lembehyne a , a novel neuritogenic polyacetylene, from a marine sponge of Haliclona sp Tetrahedron. 56: 9945-9948. DOI: 10.1016/S0040-4020(00)00973-X  0.398
2000 Murakami N, Wang W, Ohyabu N, Ito T, Tamura S, Aoki S, Kobayashi M, Kitagawa I. Synthesis of amide analogs of arenastatin A Tetrahedron. 56: 9121-9128. DOI: 10.1016/S0040-4020(00)00766-3  0.593
2000 Aoki S, Higuchi K, Ye Y, Satari R, Kobayashi M. Melophlins A and B, Novel Tetramic Acids Reversing the Phenotype of ras-Transformed Cells, from the Marine Sponge Melophlus sarassinorum Tetrahedron. 56: 1833-1836. DOI: 10.1016/S0040-4020(00)00092-2  0.332
1999 Kuwajima H, Taneda Y, Chen WZ, Kawanishi T, Hori K, Taniyama T, Kobayashi M, Ren J, Kitagawa I. Variation of chemical constituents in processed licorice roots: Quantitative determination of saponin and flavonoid constituents in bark removed and roasted licorice roots Yakugaku Zasshi. 119: 945-955. PMID 10630100 DOI: 10.1248/Yakushi1947.119.12_945  0.566
1999 Kobayashi M, Kitagawa I. Marine spongean cytotoxins Journal of Natural Toxins. 8: 249-258. PMID 10410335  0.582
1999 Aoki S, Higuchi K, Kato A, Murakami N, Kobayashi M. Myrmekiosides a and b, novel mono-o-alkyl-diglycosylglycerols reversing tumor cell morphology of ras-transformed cells from a marine sponge of myrmekioderma sp Tetrahedron. 55: 14865-14870. DOI: 10.1016/S0040-4020(99)00970-9  0.358
1999 Aoki S, Setiawan A, Yoshioka Y, Higuchi K, Fudetani R, Chen Z, Sumizawa T, Akiyama S, Kobayashi M. Reversal of multidrug resistance in human carcinoma cell line by agosterols, marine spongean sterols Tetrahedron. 55: 13965-13972. DOI: 10.1016/S0040-4020(99)00870-4  0.381
1998 Murakami N, Umezome T, Mahmud T, Sugimoto M, Kobayashi M, Wataya Y, Kim HS. Anti-malarial activities of acylated bruceolide derivatives. Bioorganic & Medicinal Chemistry Letters. 8: 459-62. PMID 9871598 DOI: 10.1016/S0960-894X(98)00045-6  0.655
1998 Kitagawa I, Chen WZ, Taniyama T, Harada E, Hori K, Kobayashi M, Ren J. Quantitative determination of constituents in various licorice roots by means of high performance liquid chromatography Yakugaku Zasshi. 118: 519-528. PMID 9868382 DOI: 10.1248/Yakushi1947.118.11_519  0.57
1998 Kitagawa I, Hori K, Kawanishi T, Kobayashi M, Kawanishi F. On the constituents of the root of Fukuchiyama-jio, the hybrid of Rehmannia glutinosa var. purpurea and R. glutinosa forma hueichingensis Yakugaku Zasshi. 118: 464-475. PMID 9800518 DOI: 10.1248/Yakushi1947.118.10_464  0.617
1998 Kobayashi M, Wang W, Tsutsui Y, Sugimoto M, Murakami N. Absolute stereostructure and total synthesis of leptomycin B Tetrahedron Letters. 39: 8291-8294. DOI: 10.1016/S0040-4039(98)01809-7  0.317
1998 Aoki S, Yoshioka Y, Miyamoto Y, Higuchi K, Setiawan A, Murakami N, Chen Z, Sumizawa T, Akiyama S, Kobayashi M. Agosterol A, a novel polyhydroxylated sterol acetate reversing multidrug resistance from a marine sponge of Spongia sp. Tetrahedron Letters. 39: 6303-6306. DOI: 10.1016/S0040-4039(98)01336-7  0.346
1998 Murakami N, Wang W, Aoki M, Tsutsui Y, Sugimoto M, Kobayashi M. Total synthesis of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata Tetrahedron Letters. 39: 2349-2352. DOI: 10.1016/S0040-4039(98)00151-8  0.325
1997 Itoh N, Kimura T, Nakanishi H, Muto N, Kobayashi M, Kitagawa I, Tanaka K. Metallothionein-independent hepatoprotection by zinc and sakuraso-saponin Toxicology Letters. 93: 135-140. PMID 9486949 DOI: 10.1016/S0378-4274(97)00086-6  0.545
1997 Kobayashi M, Mahmud T, Yoshioka N, Shibuya H, Kitagawa I. Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis Chemical and Pharmaceutical Bulletin. 45: 1615-1619. PMID 9353889 DOI: 10.1248/Cpb.45.1615  0.732
1997 Utoguchi N, Nakata T, Cheng HH, Ikeda K, Makimoto H, Mu Y, Nakagawa S, Kobayashi M, Kitagawa I, Mayumi T. Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion Inflammation. 21: 223-233. PMID 9187964 DOI: 10.1023/A:1027374321718  0.596
1997 Murakami N, Wang W, Aoki M, Tsutsui Y, Higuchi K, Aoki S, Kobayashi M. Absolute stereostructure of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata Tetrahedron Letters. 38: 5533-5536. DOI: 10.1016/S0040-4039(97)01194-5  0.348
1997 Kobayashi M, Higuchi K, Murakami N, Tajima H, Aoki S. Callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata Tetrahedron Letters. 38: 2859-2862. DOI: 10.1016/S0040-4039(97)00482-6  0.395
1997 Kobayashi M, Mahmud T, Umezome T, Wang W, Murakami N, Kitagawa I. The absolute stereostructures of the polyacetylenic constituents of Ginseng Radix Rubra Tetrahedron. 53: 15691-15700. DOI: 10.1016/S0040-4020(97)10026-6  0.706
1997 Itoh N, Morishita Y, Tanaka T, Muto N, Kobayashi M, Kitagawa I, Tanaka K. Metallothionein induction and hepatoprotection by echinoside A and sakuraso-saponin Phytotherapy Research. 11: 132-135. DOI: 10.1002/(Sici)1099-1573(199703)11:2<132::Aid-Ptr52>3.0.Co;2-Z  0.547
1996 Kitagawa I, Mahmud T, Yokota K, Nakagawa S, Mayumi T, Kobayashi M, Shibuya H. Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica. Chemical & Pharmaceutical Bulletin. 44: 2009-14. PMID 8945767 DOI: 10.1248/Cpb.44.2009  0.748
1996 Kitagawa I, Wei H, Nagao S, Mahmud T, Hori K, Kobayashi M, Uji T, Shibuya H. Indonesian Medicinal Plants. XIV. Characterization of 3'-O-Caffeoylsweroside, a new secoiridoid glucoside, and kelampayosides A and B, two new phenolic apioglucosides, from the bark of Anthocephalus chinensis (Rubiaceae). Chemical & Pharmaceutical Bulletin. 44: 1162-7. PMID 8814946 DOI: 10.1248/Cpb.44.1162  0.729
1996 Kobayashi M, Mahmud T, Tajima H, Wang W, Aoki S, Nakagawa S, Mayumi T, Kitagawa I. Marine natural products. XXXVI. Biologically active polyacetylenes, adociacetylenes A, B, C, and D, from an Okinawan Marine sponge of Adocia sp. Chemical & Pharmaceutical Bulletin. 44: 720-4. PMID 8681403 DOI: 10.1248/Cpb.44.720  0.783
1996 Shinkai K, Akedo H, Mukai M, Imamura F, Isoai A, Kobayashi M, Kitagawa I. Inhibition of in vitro tumor cell invasion by ginsenoside Rg3. Japanese Journal of Cancer Research : Gann. 87: 357-62. PMID 8641966 DOI: 10.1111/J.1349-7006.1996.Tb00230.X  0.571
1996 Hirata K, Nakagami H, Takashina J, Mahmud T, Kobayashi M, In Y, Ishida T, Miyamoto K. Novel violet pigment, nostocine a, an extracellular metabolite from cyanobacterium Nostoc spongiaeforme Heterocycles. 43: 1513-1519. DOI: 10.3987/Com-96-7494  0.62
1996 Kobayashi M, Aoki S, Gato K, Kitagawa I. Marine Natural Products. XXXVIII. Absolute Stereostructures of Altohyrtins A, B, and C and 5-Desacetylaltohyrtin A, Potent Cytotoxic Macrolides, from the Okinawan Marine Sponge Hyrtios altum Chemical & Pharmaceutical Bulletin. 44: 2142-2149. DOI: 10.1248/Cpb.44.2142  0.651
1996 Kobayashi M, Chen Y, Higuchi K, Aoki S, Kitagawa I. Marine Natural Products. XXXVII. Aragusteroketals A and C, Tow Novel Cytotoxic Steroids from a Marine Sponge of Xestospongia sp. Chemical & Pharmaceutical Bulletin. 44: 1840-1842. DOI: 10.1248/Cpb.44.1840  0.687
1995 Kitagawa I, Mahmud T, Kobayashi M, Roemantyo, Shibuya H. Taxol and its related taxoids from the needles of Taxus sumatrana. Chemical & Pharmaceutical Bulletin. 43: 365-7. PMID 7728941 DOI: 10.1248/Cpb.43.365  0.747
1995 Kobayashi M, Wang W, Ohyabu N, Kurosu M, Kitagawa I. Improved total synthesis and structure-activity relationship of arenastatin A, a potent cytotoxic spongean depsipeptide. Chemical & Pharmaceutical Bulletin. 43: 1598-600. PMID 7586087 DOI: 10.1248/Cpb.43.1598  0.653
1995 Kobayashi M, Chen YJ, Aoki S, In Y, Ishida T, Kitagawa I. Four new β-carboline alkaloids isolated from two Okinawan marine sponges of Xestospongia sp. and Haliclona sp.) Tetrahedron. 51: 3727-3736. DOI: 10.1016/0040-4020(95)95723-9  0.653
1994 Kobayashi M, Okamoto T, Hayashi K, Yokoyama N, Sasaki T, Kitagawa I. Marine natural products. XXXII. Absolute configurations of C-4 of the manoalide family, biologically active sesterterpenes from the marine sponge Hyrtios erecta. Chemical & Pharmaceutical Bulletin. 42: 265-70. PMID 8149454 DOI: 10.1248/Cpb.42.265  0.614
1994 Kobayashi M, Kawazoe K, Okamoto T, Sasaki T, Kitagawa I. Marine natural products. XXXI. Structure-activity correlation of a potent cytotoxic dimeric macrolide swinholide A, from the Okinawan marine sponge Theonella swinhoei, and its isomers. Chemical & Pharmaceutical Bulletin. 42: 19-26. PMID 8124763  0.602
1994 Shioda M, Kano K, Kobayashi M, Kitagawa I, Shoji M, Yoshida S, Ikegami S. Differential inhibition of eukaryotic DNA polymerases by halenaquinol sulfate, a p-hydroquinone sulfate obtained from a marine sponge. Febs Letters. 350: 249-52. PMID 8070573 DOI: 10.1016/0014-5793(94)00777-2  0.546
1994 Kitagawa I, Simanjuntak P, Hori K, Nagami N, Mahmud T, Shibuya H, Kobayashi M. Indonesian medicinal plants. VII. Seven new clerodane-type diterpenoids, peronemins A2, A3, B1, B2, B3, C1, and D1, from the leaves of Peronema canescens (Verbenaceae). Chemical & Pharmaceutical Bulletin. 42: 1050-5. PMID 8069955 DOI: 10.1248/Cpb.42.1050  0.742
1994 Kobayashi M, Kanzaki K, Katayama S, Ohashi K, Okada H, Ikegami S, Kitagawa I. Marine natural products. XXXIII. Theonellapeptolide IId, a new tridecapeptide lactone from the Okinawan marine sponge Theonella swinhoei. Chemical & Pharmaceutical Bulletin. 42: 1410-5. PMID 7923463 DOI: 10.1248/Cpb.42.1410  0.626
1994 Kobayashi M, Aoki S, Gato K, Matsunami K, Kurosu M, Kitagawa I. Marine natural products. XXXIV. Trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. separated from the marine sponge Hyrtios altum. Chemical & Pharmaceutical Bulletin. 42: 2449-51. PMID 7697760 DOI: 10.1248/Cpb.42.2449  0.65
1994 Kobayashi M, Kurosu M, Wang W, Kitagawa I. A Total Synthesis Of Arenastatin A, An Extremely Potent Cytotoxic Depsipeptide, From The Okinawan Marine Sponge Dysidea Arenaria Chemical & Pharmaceutical Bulletin. 42: 2394-2396. DOI: 10.1248/Cpb.42.2394  0.643
1994 Kobayashi M, Kurosu M, Ohyabu N, Wang W, Fujii S, Kitagawa I. The Absolute Stereostructure Of Arenastatin A, A Potent Cytotoxic Depsipeptide From The Okinawan Marine Sponge Dysidea Arenaria Chemical & Pharmaceutical Bulletin. 42: 2196-2198. DOI: 10.1248/Cpb.42.2196  0.65
1994 Kitagawa I, Simanjuntak P, Watano T, Shibuya H, Fujii S, Yamagata Y, Kobayashi M. Indonesian medicinal plants. XI: Chemical structures of caesaldekarins a and b, two new cassane-type furanoditerpenes from the roots of Caesalpinia major (Fabaceae) Chemical & Pharmaceutical Bulletin. 42: 1798-1802. DOI: 10.1248/Cpb.42.1798  0.651
1994 Kobayashi M, Aoki S, Kitagawa I. Absolute stereostructures of altohyrtin A and its congeners, potent cytotoxic macrolides from the Okinawan marine sponge hyrtios altum Tetrahedron Letters. 35: 1243-1246. DOI: 10.1016/0040-4039(94)88034-4  0.672
1994 Kobayashi M, Aoki S, Ohyabu N, Kurosu M, Wang W, Kitagawa I. Arenastatin A, a potent cytotoxic depsipeptide from the okinawan marine sponge Dysidea arenaria Tetrahedron Letters. 35: 7969-7972. DOI: 10.1016/0040-4039(94)80024-3  0.663
1993 Kobayashi M, Kondo K, Kitagawa I. Antifungal peroxyketal acids from an Okinawan marine sponge of Plakortis sp. Chemical & Pharmaceutical Bulletin. 41: 1324-6. PMID 8375002 DOI: 10.1248/Cpb.41.1324  0.596
1993 Kobayashi M, Aoki S, Sakai H, Kihara N, Sasaki T, Kitagawa I. Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum. Chemical & Pharmaceutical Bulletin. 41: 989-91. PMID 8339346  0.636
1993 Kobayashi M, Aoki S, Sakai H, Kawazoe K, Kihara N, Sasaki T, Kitagawa I. Altohyrtin A, a potent anti-tumor macrolide from the Okinawan marine sponge Hyrtios altum Tetrahedron Letters. 34: 2795-2798. DOI: 10.1016/S0040-4039(00)73564-7  0.647
1993 Kobayashi M, Uehara H, Matsunami K, Aoki S, Kitagawa I. Trichoharzin, a new polyketide produced by the imperfect fungus Trichoderma harzianum separated from the marine sponge Micale cecilia Tetrahedron Letters. 34: 7925-7928. DOI: 10.1016/S0040-4039(00)61513-7  0.631
1992 Ikegami S, Kajiyama N, Ozaki Y, Myotoishi Y, Miyashiro S, Takayama S, Kobayashi M, Kitagawa I. Selective inhibition of membrane fusion events in echinoderm gametes and embryos by halenaquinol sulfate. Febs Letters. 302: 284-6. PMID 1601136 DOI: 10.1016/0014-5793(92)80460-X  0.538
1992 Kobayashi M, Kawazoe K, Katori T, Kitagawa I. Marine Natural Products. XXX. Two New 3-Keto-4-methylene Steroids, Theonellasterone and Conicasterone, and a Diels-Alder Type Dimeric Steroid Bistheonellasterone, from the Okinawan Marine Sponge Theonella swinhoei Chemical & Pharmaceutical Bulletin. 40: 1773-1778. DOI: 10.1248/Cpb.40.1773  0.615
1992 Kobayashi M, Hayashi K, Kawazoe K, Kitagawa I. Marine Natural Products. XXIX. Heterosigma-glycolipids I, II, III, and IV, Four Diacylglyceroglycolipids Possessing ω3-Polyunsaturated Fatty Acid Residues, from the Raphidopycean Dinoflagellate Heterosigma akashiwo Chemical & Pharmaceutical Bulletin. 40: 1404-1410. DOI: 10.1248/Cpb.40.1404  0.577
1991 Kobayashi M, Lee NK, Shibuya H, Momose T, Kitagawa I. Marine natural products. XXVI. Biologically active tridecapeptide lactones from the Okinawan marine sponge Theonella swinhoei (Theonellidae). (2). Structures of theonellapeptolides Ia, Ib, Ic, and Ie. Chemical & Pharmaceutical Bulletin. 39: 1177-84. PMID 1913995 DOI: 10.1248/Cpb.39.1177  0.578
1991 Kitagawa I, Kobayashi M. Anti-tumor Marine Natural Products Journal of Synthetic Organic Chemistry Japan. 49: 1053-1061. DOI: 10.5059/Yukigoseikyokaishi.49.1053  0.632
1991 Kobayashi M, Okamoto Y, Kitagawa I. Marine Natural Products. XXVIII. The Structures of Sarasinosides A1, A2, A3, B1, B2, B3, C1, C2, and C3, Nine New Norlanostane-Triterpenoidal Oligoglycosides from the Palauan Marine Sponge Asteropus sarasinosum Chemical & Pharmaceutical Bulletin. 39: 2867-2877. DOI: 10.1248/Cpb.39.2867  0.62
1991 KOBAYASHI M, HORI M, KAN K, YASUZAWA T, MATSUI M, SUZUKI S, KITAGAWA I. Marine Natural Products. XXVII. Distribution of Lanostane-Type Triterpene Oligoglycosides in Ten Kinds of Okinawan Sea Cucumbers. Chemical & Pharmaceutical Bulletin. 39: 2282-2287. DOI: 10.1248/Cpb.39.2282  0.638
1991 Doi M, Ishida T, Kobayashi M, Kitagawa I. Molecular conformation of swinholide A, a potent cytotoxic dimeric macrolide from the Okinawan marine sponge Theonella swinhoei: x-ray crystal structure of its diketone derivative Journal of Organic Chemistry. 56: 3629-3632. DOI: 10.1021/Jo00011A033  0.584
1991 Kitagawa I, Lee NK, Kobayashi M, Shibuya H. Marine natural products. XXV. Biologically active tridecapeptide lactones from the Okinawan marine sponge Theonella swinhoei (Theonellidae). Structure of theonellapeptolide Id Tetrahedron. 47: 2169-2180. DOI: 10.1016/S0040-4020(01)96128-9  0.628
1990 Kitagawa I, Kobayashi M. [Anti-tumor marine natural products]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 17: 322-9. PMID 2310201  0.573
1990 Kobayashi M, Tanaka J, Katori T, Kitagawa I. Marine natural products. XXIII. Three new cytotoxic dimeric macrolides, swinholides B and C and isoswinholide A, congeners of swinholide A, from the Okinawan marine sponge Theonella swinhoei. Chemical & Pharmaceutical Bulletin. 38: 2960-6. PMID 2085878 DOI: 10.1248/Cpb.38.2960  0.77
1990 TANAKA J, HIGA T, KOBAYASHI M, KITAGAWA I. Marine natural products. XXIV. The absolute stereostructure of misakinolide A, a potent cytotoxic dimeric macrolide from an Okinawan marine sponge Theonella sp. Chemical & Pharmaceutical Bulletin. 38: 2967-2970. DOI: 10.1248/Cpb.38.2967  0.809
1990 Kaneko F, Kobayashi M, Kitagawa Y, Matsuura Y. Structure of stearic acid E form Acta Crystallographica Section C Crystal Structure Communications. 46: 1490-1492. DOI: 10.1107/S0108270189012679  0.309
1990 Kitagawa I, Kobayashi M, Katori T, Yamashita M, Tanaka J, Doi M, Ishida T. Absolute stereostructure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge Theonella swinhoei Journal of the American Chemical Society. 112: 3710-3712. DOI: 10.1021/Ja00165A094  0.759
1989 Kobayashi M, Kawazoe K, Kitagawa I. Araguspongines B, C, D, E, F, G, H, and J, new vasodilative bis-1-oxaquinolizidine alkaloids from an okinawan marine sponge, Xestospongia sp. Chemical & Pharmaceutical Bulletin. 37: 1676-8. PMID 2776247 DOI: 10.1248/Cpb.37.1676  0.628
1989 Kitagawa I, Kobayashi M. [Anti-tumor natural products isolated from marine organisms]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 16: 1-8. PMID 2563218  0.585
1989 KITAGAWA I, HAYASHI K, KOBAYASHI M. Heterosigma-glycolipids I and II, two new galactolipids containing octadecatetraenoyl and eicosapentaenoyl residues, from a raphidophyte dinoflagellate Heterosigma sp. Chemical & Pharmaceutical Bulletin. 37: 849-851. DOI: 10.1248/Cpb.37.849  0.606
1989 KITAGAWA I, KOBAYASHI M, HORI M, KYOGOKU Y. Marine natural products. XVIII. Four lanostane-type triterpene oligoglycosides, bivittosides A, B, C, and D, from the Okinawan sea cucumber Bohadschia bivittata Mitsukuri. Chemical & Pharmaceutical Bulletin. 37: 61-67. DOI: 10.1248/Cpb.37.61  0.647
1989 KITAGAWA I, KOBAYASHI M, LEE NK, OYAMA Y, KYOGOKU Y. Marine natural products. XX. Bioactive scalarane-type bishomosesterterpenes from the okinawan marine sponge Phyllospongia foliascens. Chemical & Pharmaceutical Bulletin. 37: 2078-2082. DOI: 10.1248/Cpb.37.2078  0.671
1989 KITAGAWA I, KOBAYASHI M, SON BW, SUZUKI S, KYOGOKU Y. Marine natural products. XIX. Pervicosides A, B, and C, lanostane-type triterpene-oligoglycoside sulfates from the sea cucumber Holothuria pervicax. Chemical & Pharmaceutical Bulletin. 37: 1230-1234. DOI: 10.1248/Cpb.37.1230  0.636
1989 Kobayashi M, Kawazoe K, Kitagawa I. Aragupetrosine a, a new vasodilative macrocyclic quinolizidine alkaloid from an Okinawan marine sponge sp Tetrahedron Letters. 30: 4149-4152. DOI: 10.1016/S0040-4039(00)99345-6  0.629
1989 Kobayashi M, Tanaka Ji, Katori T, Matsuura M, Kitagawa I. Structure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge Theonella Swinhoei Tetrahedron Letters. 30: 2963-2966. DOI: 10.1016/S0040-4039(00)99170-6  0.767
1987 Kitagawa I, Lee NK, Kobayashi M, Shibuya H. Structure of theonellapeptolide Ie, a new tridecapeptide lactone from an Okinawan marine sponge, Theonella sp. (Theonellidae). Chemical & Pharmaceutical Bulletin. 35: 2129-32. PMID 3664821 DOI: 10.1248/Cpb.35.2129  0.635
1987 Kitagawa I, Kobayashi M, Okamoto Y, Yoshikawa M, Hamamoto Y. Structures of sarasinosides A1, B1, and C1; new norlanostane-triterpenoid oligoglycosides from the Palauan marine sponge Asteropus sarasinosum. Chemical & Pharmaceutical Bulletin. 35: 5036-9. PMID 3451822 DOI: 10.1248/Cpb.35.5036  0.657
1987 Kitagawa I, Cui Z, Son BW, Kobayashi M, Kyogoku Y. Marine natural products. XVII. Nephtheoxydiol, a new cytotoxic hydroperoxy-germacrane sesquiterpene, and related sesquiterpenoids from an Okinawan soft coral of Nephthea sp. (Nephtheidae). Chemical & Pharmaceutical Bulletin. 35: 124-35. PMID 2885097 DOI: 10.1248/Cpb.35.124  0.592
1986 Kobayashi M, Son BW, Kyogoku Y, Kitagawa I. Kericembrenolides A, B, C, D, and E, five new cytotoxic cembrenolides from the Okinawan soft coral Clavularia koellikeri. Chemical & Pharmaceutical Bulletin. 34: 2306-9. PMID 3742667 DOI: 10.1248/Cpb.34.2306  0.642
1986 KITAGAWA I, ZHENG C, CAI Y, KOBAYASHI M, KYOGOKU Y. Marine natural products. XVI Structures of five new diterpenes from an Okinawan soft coral of Xenia sp. (Xeniidae). Chemical & Pharmaceutical Bulletin. 34: 4641-4652. DOI: 10.1248/Cpb.34.4641  0.634
1986 KITAGAWA I, KOBAYASHI M, ZHENG C, KIYOTA Y, OHNISHI M. Marine natural products. XV Chemical constituents of an Okinawan soft coral of Xenia sp. (Xeniidae). Chemical & Pharmaceutical Bulletin. 34: 4590-4596. DOI: 10.1248/Cpb.34.4590  0.597
1986 Kitagawa I, Kobayashi M, Lee NK, Shibuya H, Kawata Y, Sakiyama F. Structure of theonellapeptolide Id, a new bioactive peptolide from an Okinawan marine sponge, Theonella sp. (Theonelliae). Chemical & Pharmaceutical Bulletin. 34: 2664-2667. DOI: 10.1248/Cpb.34.2664  0.659
1985 Kitagawa I, Kobayashi M, Inamoto T, Fuchida M, Kyogoku Y. Marine natural products. XIV. Structures of echinosides A and B, antifungal lanostane-oligosides from the sea cucumber Actinopyga echinites (Jaeger). Chemical & Pharmaceutical Bulletin. 33: 5214-24. PMID 3833380 DOI: 10.1248/Cpb.33.5214  0.597
1985 Kobayashi M, Zheng C, Yang C, Kyogoku Y, Kitagawa I. Xeniolone and isoxeniolone. Two new diterpenes having a perhydroazulene skeleton from an Okinawan soft coral of Xenia sp. Chemical & Pharmaceutical Bulletin. 33: 1309-1312. DOI: 10.1248/Cpb.33.1309  0.634
1985 Kobayashi M, Shimizu N, Kyogoku Y, Kitagawa I. Halenaquinol and halenaquinol sulfate, pentacyclic hydroquinones from the Okinawan marine sponge Xestospongia sapra. Chemical & Pharmaceutical Bulletin. 33: 1305-1308. DOI: 10.1248/Cpb.33.1305  0.643
1985 Kobayashi M, Shimizu N, Kitagawa I, Kyogoku Y, Harada N, Uda H. Absolute stereostructures of halenaquinol and halenaquinol sulfate, pentacyclic hydroquinones from the okinawan marine sponge xestospongia sapra, as determined by theoretical calculation of CD spectra Tetrahedron Letters. 26: 3833-3836. DOI: 10.1016/S0040-4039(00)89263-1  0.55
1985 Kitagawa I, Kobayashi M, Yasuzawa T, Son BW, Yoshihara M, Kyogoku Y. New prostanoids from soft coral Tetrahedron. 41: 995-1005. DOI: 10.1016/S0040-4020(01)96467-1  0.659
1984 Nishihata T, Kato J, Kim KH, Kobayashi M, Kitagawa I, Kamada A. Formation and hydrolysis of enamine in aqueous solution. Chemical & Pharmaceutical Bulletin. 32: 4545-50. PMID 6442627 DOI: 10.1248/Cpb.32.4545  0.533
1984 Kobayashi M, Son BW, Kyogoku Y, Kitagawa I. Clavukerin C, a new trinor-guaiane sesquiterpene having a hydroperoxy function, from the Okinawan soft coral Clavularia koellikeri. Chemical & Pharmaceutical Bulletin. 32: 1667-1670. DOI: 10.1248/Cpb.32.1667  0.647
1984 Kobayashi M, Lee NK, Son BW, Yanag K, Kyogoku Y, Kitagawa I. Stoloniferone-a, -b, -c, and -d, four new cytotoxic steroids from the okinawan soft coral clavularia viridis Tetrahedron Letters. 25: 5925-5928. DOI: 10.1016/S0040-4039(01)81722-6  0.644
1984 Kobayashi M, Wha Son B, Fujiwara T, Kyogoku Y, Kitagawa I. Neodolabelline, a methyl migrated dolabellane-type diterpene from the okinawan soft coral clavularia koellikeri Tetrahedron Letters. 25: 5543-5546. DOI: 10.1016/S0040-4039(01)81621-X  0.599
1984 Kobayashi M, Kiyota Y, Orito S, Kyogoku Y, Kitagawa I. Five new steroidal glycosides, pregnedioside-A, -B, and their three monoacetates, from an Okinawan soft coral of Alcyonium sp Tetrahedron Letters. 25: 3731-3734. DOI: 10.1016/0040-4039(84)80117-3  0.634
1983 KIKUCHI H, TSUKITANI Y, SHIMIZU I, KOBAYASHI M, KITAGAWA I. Marine natural products. XI. An antiinflammatory scalarane-type bishomosesterterpene, foliaspongin, from the Okinawan marine sponge Phyllospongia foliascens (Pallas). Chemical & Pharmaceutical Bulletin. 31: 552-556. DOI: 10.1248/Cpb.31.552  0.639
1983 KITAGAWA I, KOBAYASHI M, KITANAKA K, KIDO M, KYOGOKU Y. Marine natural products. XII. On the chemical constituents of the Okinawan marine sponge Hymeniacidon aldis. Chemical & Pharmaceutical Bulletin. 31: 2321-2328. DOI: 10.1248/Cpb.31.2321  0.607
1983 Kobayashi M, Son B, Kido M, Kyogoku Y, Kitagawa I. Clavukerin A, a new trinor-guaiane sesquiterpene from the okinawan soft coral Clavularia koellikeri. Chemical & Pharmaceutical Bulletin. 31: 2160-2163. DOI: 10.1248/Cpb.31.2160  0.611
1983 Kobayashi M, Yasuzawa T, Yoshihara M, Son B, Kyogoku Y, Kitagawa I. Absolute stereostructures of claviridenone-A, -B, -C, and -D four prostanoids from the Okinawan soft coral Clavularia viridis. Chemical & Pharmaceutical Bulletin. 31: 1440-1443. DOI: 10.1248/Cpb.31.1440  0.633
1982 KIKUCHI H, TSUKITANI Y, MANDA T, FUJII T, NAKANISHI H, KOBAYASHI M, KITAGAWA I. Marine natural products. X. Pharmacologically active glycolipids from the okinawan marine sponge Phyllospongia foliascens (Pallas). Chemical & Pharmaceutical Bulletin. 30: 3544-3547. DOI: 10.1248/Cpb.30.3544  0.592
1982 Kobayashi M, Yasuzawa T, Kyogoku Y, Kido M, Kitagawa I. Three new ent-valerenane sesquiterpenes from an okinawan soft coral. Chemical & Pharmaceutical Bulletin. 30: 3431-3434. DOI: 10.1248/Cpb.30.3431  0.619
1982 KITAGAWA I, KOBAYASHI M, KYOGOKU Y. Marine natural products. IX. Structural elucidation of triterpenoidal oligoglycosides from the Bahamean sea cucumber Actinopyga agassizi Selenka. Chemical & Pharmaceutical Bulletin. 30: 2045-2050. DOI: 10.1248/Cpb.30.2045  0.649
1982 Kobayashi M, Yasuzawa T, Yoshihara M, Akutsu H, Kyogoku Y, Kitagawa I. Four new prostanoids: Claviridenone-A, -B, -C, and -D from the okinawan soft coral Tetrahedron Letters. 23: 5331-5334. DOI: 10.1016/S0040-4039(00)85831-1  0.652
1981 KITAGAWA I, KOBAYASHI M, HORI M, KYOGOKU Y. Structures of four new triterpenoidal oligoglycosides, bivittoside A,B,C, and D, from the sea cucumber Bohadschia bivittata Mitsukuri. Chemical & Pharmaceutical Bulletin. 29: 282-285. DOI: 10.1248/Cpb.29.282  0.672
1981 KITAGAWA I, KOBAYASHI M, INAMOTO T, YASUZAWA T, KYOGOKU Y. The structures of six antifungal oligoglycosides, stichlorosides A1,A2,B1,B2,C1, and C2, from the sea cucumber Stichopus chloronotus (Brandt). Chemical & Pharmaceutical Bulletin. 29: 2387-2391. DOI: 10.1248/Cpb.29.2387  0.623
1981 KITAGAWA I, NISHINO T, KOBAYASHI M, MATSUNO T, AKUTSU H, KYOGOKU Y. Marine natural products. VII. Bioactive triterpene-oligoglycosides from the sea cucumber Holothuria leucospilota Brandt (1). Structure of holothurin B. Chemical & Pharmaceutical Bulletin. 29: 1942-1950. DOI: 10.1248/Cpb.29.1942  0.645
1981 KIKUCHI H, TSUKITANI Y, SHIMIZU I, KOBAYASHI M, KITAGAWA I. Foliaspongin, an antiinflammatory bishomosesterterpene from the marine sponge Phyllospongia foliascens (Pallas). Chemical & Pharmaceutical Bulletin. 29: 1492-1494. DOI: 10.1248/Cpb.29.1492  0.65
1981 KITAGAWA I, KOBAYASHI M, INAMOTO T, YASUZAWA T, KYOGOKU Y, KIDO M. Stichlorogenol and dehydrostichlorogenol,genuine aglycones of stichlorosides A1,B1,C1 and A2,B2,C2,from the sea cucumber Stichopus chloronotus (Brandt). Chemical & Pharmaceutical Bulletin. 29: 1189-1192. DOI: 10.1248/Cpb.29.1189  0.621
1981 Kobayashi M, Yasuzawa T, Kobayashi Y, Kyogoku Y, Kitagawa I. Alcyonolide, a novel diterpenoid from a soft coral Tetrahedron Letters. 22: 4445-4448. DOI: 10.1016/S0040-4039(01)82979-8  0.641
1980 KITAGAWA I, INAMOTO T, FUCHIDA M, OKADA S, KOBAYASHI M, NISHINO T, KYOGOKU Y. Structures of echinoside A and B, two antifungal oligoglycosides from the sea cucumber Actinopyga echinites (Jaeger). Chemical & Pharmaceutical Bulletin. 28: 1651-1653. DOI: 10.1248/Cpb.28.1651  0.642
1979 Kitagawa I, Hamamoto Y, Kobayashi M. Sulfonoglycolipid from the sea urchin Anthocidaris crassispina A. Agassiz. Chemical & Pharmaceutical Bulletin. 27: 1394-7. PMID 540352 DOI: 10.1248/Cpb.27.1934  0.597
1978 KITAGAWA I, YAMANAKA H, KOBAYASHI M, NISHINO T, YOSIOKA I, SUGAWARA T. Saponin and sapogenol. XXVII. Revised structures of holotoxin A and holotoxin B, two antifungal oligoglycosides from the sea cucumber Stichopus japonicus Selenka. Chemical & Pharmaceutical Bulletin. 26: 3722-3731. DOI: 10.1248/Cpb.26.3722  0.588
1978 KITAGAWA I, KOBAYASHI M. Saponin and sapogenol. XXVI. Steroidal saponins from the starfish Acanthaster planci L. (crown of thorns). 2. Structure of the major saponin thornasteroside A. Chemical & Pharmaceutical Bulletin. 26: 1864-1873. DOI: 10.1248/Cpb.26.1864  0.591
1978 KITAGAWA I, KOBAYASHI M, SUGAWARA T. Saponin and sapogenol. XXV. Steroidal saponins from the starfish Acanthaster planci L. (crown of thorns). 1. Structures of two genuine sapogenols, thornasterol A and thornasterol B, and their sulfates. Chemical & Pharmaceutical Bulletin. 26: 1852-1863. DOI: 10.1248/Cpb.26.1852  0.603
1977 Kitagawa I, Kobayashi M. On the structure of the major saponin from the starfish acanthaster planci Tetrahedron Letters. 18: 859-862. DOI: 10.1016/S0040-4039(01)92775-3  0.601
1975 Kitagawa I, Kobayashi M, Sugawara T, Yosioka I. Thornasterol A and B, two genuine sapogenols from the starfish acanthaster planci Tetrahedron Letters. 16: 967-970. DOI: 10.1016/S0040-4039(00)72032-6  0.581
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