Christian B. Anfinsen
Affiliations: | Johns Hopkins University School of Medicine, Baltimore, MD, United States |
Area:
Protein chemistryWebsite:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1972/anfinsen-bio.htmlGoogle:
"Christian Boemer Anfinsen"Bio:
(1916 - 1995)
The Nobel Prize in Chemistry 1972 was divided, one half awarded to Christian B. Anfinsen "for his work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation", the other half jointly to Stanford Moore and William H. Stein "for their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule".
http://www.nasonline.org/member-directory/deceased-members/58204.html
http://www.asbmb.org/uploadedfiles/aboutus/asbmb_history/past_presidents/1970s/1971Anfinsen.html
http://profiles.nlm.nih.gov/ps/retrieve/Collection/CID/KK
DOI: 10.1002/jcp.1030200210
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Mean distance: 8.17 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| A. Baird Hastings | grad student | 1943 | Harvard Medical School | |
| (Quantitative Histochemical Studies of the Retina) | ||||
| Kaj Linderstrøm-Lang | research scientist | 1954-1955 | Carlsberg Laboratory | |
Children
Sign in to add trainee| M. Christina White | research assistant | 1992-1993 | Johns Hopkins |
| Daniel Steinberg | grad student | 1952 | Harvard |
| Charles J. Epstein | post-doc | NIH (Neurotree) | |
| Thressa Campbell Stadtman | post-doc | 1950 | Harvard Medical School |
| Michael Sela | post-doc | 1956-1957 | NIH |
| Robert S. Adelstein | post-doc | 1961 | NIH |
| Edgar Haber | post-doc | 1959-1962 | NIH |
| Pedro Cuatrecasas | post-doc | 1966-1967 | NIH |
| Irwin M. Chaiken | post-doc | 1969-1970 | NIH |
| Theodore Adolphus Bremner | post-doc | 1974 | NIH (GenetiTree) |
| Ben M. Dunn | post-doc | 1971-1974 | NIH (Microtree) |
| Bruce Furie | post-doc | 1972-1974 | NIH (NIAMDD) |
| John A. Gerlt | post-doc | 1974-1975 | NIH |
| Martha Vaughan | research scientist | NIH | |
| Edward David Korn | research scientist | 1954 | NIH |
| Robert F. Goldberger | research scientist | 1961-1964 | National Institutes of Health, Bethesda (Microtree) |
Publications
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| Furie B, Schechter AN, Sachs DH, et al. (1975) An immunological approach to the conformational equilibrium of staphylococcal nuclease. Journal of Molecular Biology. 92: 497-506 |
| Dunn BM, Anfinsen CB. (1974) Kinetics of Woodward's Reagent K hydrolysis and reaction with staphylococcal nuclease. The Journal of Biological Chemistry. 249: 3717-23 |
| Furie B, Schechter AN, Sachs DH, et al. (1974) Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease. Biochemistry. 13: 1561-6 |
| Sachs DH, Schecter AN, Eastlake A, et al. (1974) Immunological distinction between the possible origins of enzymatic activity in a polypeptide fragment of staphylococcal nuclease. Nature. 251: 242-4 |
| Eastlake A, Sachs DH, Schechter AN, et al. (1974) Binding of univalent antibody fragments to a distinct antigenic determinant of staphylococcal nuclease. Biochemistry. 13: 1567-71 |
| Furie B, Eastlake A, Schechter AN, et al. (1973) The interaction of the lanthanide ions with staphylococcal nuclease. The Journal of Biological Chemistry. 248: 2821-5 |
| Fuchs S, Sela M, Anfinsen CB. (1973) Nuclease-coated bacteriophage: a sensitive tool for studying antigenic reactivity of synthetic sequence fragments. Archives of Biochemistry and Biophysics. 154: 601-5 |
| Dunn BM, DiBello C, Anfinsen CB. (1973) The pH dependence of the steady state kinetic parameters for staphylococcal nuclease-catalyzed hydrolysis of deoxythymidine-3'-phosphate-5'-p-nitrophenylphosphate in H 2 O and D 2 O. The Journal of Biological Chemistry. 248: 4769-74 |
| Sánchez GR, Chaiken IM, Anfinsen CB. (1973) Structure-function relationships at the active site of nuclease-T'. The Journal of Biological Chemistry. 248: 3653-9 |
| Anfinsen C, Goldberger R, Schechter A. (1973) Current topics in Biochemistry. National institutes of health lectures in biomedical sciences Food and Cosmetics Toxicology. 11: 1116-1117 |