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Angela N. Koehler, Ph.D.

Affiliations: 
2014- Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Chemical biology, Deregulated transcription in disease
Website:
https://koehler-lab.mit.edu
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"Angela Koehler"
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SNBCP

Parents

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Arthur Glasfeld research assistant 1993-1997 Reed College
 (Undergraduate thesis advisor)
Stuart L. Schreiber grad student 2003 Harvard
 (Small molecule microarrays: A high -throughput tool for discovering protein-small molecule interactions.)

Children

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Nick Davis grad student MIT
Chuanxu Liu grad student MIT
Qiaoyi Wang grad student MIT
David B. Freeman grad student 2016- MIT
David B. Freeman grad student 2016- MIT
Nicholas Struntz grad student 2016- MIT
John Paul Shen grad student 2004-2005 Broad Institute (MIT/Harvard)
Mary Kathryn Doud grad student 2007-2010 Broad Institute (MIT/Harvard)
Clementine Feau grad student 2010-2012 Broad Institute (MIT/Harvard)
Melissa M. Kemp grad student 2009-2013 Broad Institute (MIT/Harvard)
Cheng Zhong grad student 2013-2013 Broad Institute (MIT/Harvard)
Rohit Thummalapalli grad student 2013-2015 MIT (Neurotree)
Francisco Caballero grad student 2012-2016 MIT
Jiyoung A. Hong grad student 2013-2016 MIT
Marius Pop grad student 2014-2016 MIT
Eric Stefan grad student 2014-2016 MIT
Thijs Wildschut grad student 2015-2016 MIT
Helen Evans grad student 2015-2017 MIT
Andre Richters grad student 2015-2017 MIT
Rui Traquette grad student 2016-2017 MIT
BETA: Related publications

Publications

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Leifer BS, Doyle SK, Richters A, et al. (2018) An Array-Based Ligand Discovery Platform for Proteins With Short Half-Lives. Methods in Enzymology. 610: 191-218
Richters A, Koehler AN. (2017) Epigenetic Modulation using Small Molecules - Targeting Histone Acetyltransferases in Disease. Current Medicinal Chemistry
Yang Z, Koehler AN, Wang L. (2016) A novel small molecule activator of nuclear receptor SHP inhibits HCC cell migration via suppressing Ccl2. Molecular Cancer Therapeutics
Zhang Z, Boskovic Z, Hussain MM, et al. (2015) Author response: Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation Elife
Waal Ld, Lewis TA, Rees MG, et al. (2015) Abstract C136: Identification of selective cancer cytotoxic modulators of phosphodiesterase 3a by predictive chemogenomics Molecular Cancer Therapeutics. 14
Waal LMd, Lewis TA, Gechijian L, et al. (2014) Abstract 4596: An integrated genomic characterization of the target of a small molecule identifies a novel cancer dependency Cancer Research. 74: 4596-4596
Koehler AN, Shamji AF, Schreiber SL. (2003) Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis. Journal of the American Chemical Society. 125: 8420-1
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