☰ Chemistry Tree

Erik J. Fernandez

Affiliations:

University of Virginia, Charlottesville, VA

Area:

Chemical Engineering, Biochemistry

Website:

http://bims.virginia.edu/faculty/erik-j-fernandez/

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"Erik Fernandez"

Mean distance: 4976.62

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Parents

Harvey W. Blanch	grad student	1989	UC Berkeley
Douglas S. Clark	grad student	1989	UC Berkeley
(Noninvasive studies of hybridoma metabolism by nuclear magnetic resonance.)

Children

Matthew L. Dickson	grad student	2000	UVA
Jennifer L. McNay	grad student	2000	UVA
Scott A. Tobler	grad student	2002	UVA
Ronald N. Keener	grad student	2003	UVA
Jace L. Fogle	grad student	2006	UVA
Jacob L. Jordan	grad student	2009	UVA
Aming Zhang	grad student	2011	UVA

Collaborators

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Publications

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O'Brien CJ, Blanco MA, Costanzo JA, et al. (2016) Modulating non-native aggregation and electrostatic protein-protein interactions with computationally designed single-point mutations. Protein Engineering, Design & Selection : Peds
Gospodarek AM, Sun W, O'Connell JP, et al. (2014) Structures of multidomain proteins adsorbed on hydrophobic interaction chromatography surfaces. Journal of Chromatography. A. 1371: 204-19
Gospodarek AM, Hiser DE, O'Connell JP, et al. (2014) Unfolding of a model protein on ion exchange and mixed mode chromatography surfaces. Journal of Chromatography. A. 1355: 238-52
Costanzo JA, O'Brien CJ, Tiller K, et al. (2014) Conformational stability as a design target to control protein aggregation. Protein Engineering, Design & Selection : Peds. 27: 157-67
Weiss WF, Zhang A, Ivanova MI, et al. (2014) Reduction of the C191-C220 disulfide of α-chymotrypsinogen A reduces nucleation barriers for aggregation. Biophysical Chemistry. 185: 79-87
Gregoire S, Zhang S, Costanzo J, et al. (2014) Cis-suppression to arrest protein aggregation in mammalian cells. Biotechnology and Bioengineering. 111: 462-74
Kim N, Remmele RL, Liu D, et al. (2013) Aggregation of anti-streptavidin immunoglobulin gamma-1 involves Fab unfolding and competing growth pathways mediated by pH and salt concentration. Biophysical Chemistry. 172: 26-36
Brummitt RK, Andrews JM, Jordan JL, et al. (2012) Thermodynamics of amyloid dissociation provide insights into aggregate stability regimes. Biophysical Chemistry. 168: 10-8
Zhang A, Singh SK, Shirts MR, et al. (2012) Distinct aggregation mechanisms of monoclonal antibody under thermal and freeze-thaw stresses revealed by hydrogen exchange. Pharmaceutical Research. 29: 236-50
Wong HE, Qi W, Choi HM, et al. (2011) A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-β neurotoxicity by generating nontoxic aggregates. Acs Chemical Neuroscience. 2: 645-57

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