Carl O. Pabo
Affiliations: | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
protein-DNA recognitionWebsite:
http://www.hhmi.org/research/investigators/pabo_bio.htmlGoogle:
"Carl Pabo"Bio:
http://www.nasonline.org/member-directory/members/59647.html
http://www.proteanfutures.com/
Mean distance: 7.74 | S | N | B | C | P |
Parents
Sign in to add mentorMark Ptashne | grad student | 1980 | Harvard | |
(Structural study of the lambda repressor) | ||||
Stephen C. Harrison | post-doc | Harvard | ||
Don C. Wiley | post-doc | Harvard |
Children
Sign in to add traineeErnest Fraenkel | grad student | MIT (Plant Biology Tree) | |
Alan D. Frankel | grad student | ||
Jin-Soo Kim | grad student | ||
Nikola P. Pavletich | grad student | 1991 | Johns Hopkins Medical School |
Lisa C. Tucker-Kellogg | grad student | 1993-1997 | (Neurotree) |
Nikola P. Pavletich | post-doc | MIT | |
Cynthia Wolberger | post-doc | Johns Hopkins | |
H. Eric Xu | post-doc |
BETA: Related publications
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Publications
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Nguyen-Hackley DH, Ramm E, Taylor CM, et al. (2004) Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands. Biochemistry. 43: 3880-90 |
Wolfe SA, Grant RA, Pabo CO. (2003) Structure of a designed dimeric zinc finger protein bound to DNA. Biochemistry. 42: 13401-9 |
Hurt JA, Thibodeau SA, Hirsh AS, et al. (2003) Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection. Proceedings of the National Academy of Sciences of the United States of America. 100: 12271-6 |
Peisach E, Pabo CO. (2003) Constraints for zinc finger linker design as inferred from X-ray crystal structure of tandem Zif268-DNA complexes. Journal of Molecular Biology. 330: 1-7 |
Jamieson AC, Miller JC, Pabo CO. (2003) Drug discovery with engineered zinc-finger proteins. Nature Reviews. Drug Discovery. 2: 361-8 |
Miller JC, Pabo CO. (2001) Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. Journal of Molecular Biology. 313: 309-15 |
Wolfe SA, Grant RA, Elrod-Erickson M, et al. (2001) Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes. Structure (London, England : 1993). 9: 717-23 |
Wang BS, Grant RA, Pabo CO. (2001) Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA. Nature Structural Biology. 8: 589-93 |
Pabo CO, Peisach E, Grant RA. (2001) Design and selection of novel Cys2His2 zinc finger proteins. Annual Review of Biochemistry. 70: 313-40 |
Pabo CO, Nekludova L. (2000) Geometric analysis and comparison of protein-DNA interfaces: why is there no simple code for recognition? Journal of Molecular Biology. 301: 597-624 |