George W. J. Fleet

Affiliations: 
Chemistry University of Oxford, Oxford, United Kingdom 
Area:
carbohydrate chemistry
Website:
http://research.chem.ox.ac.uk/george-fleet.aspx
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"George Fleet"
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Parents

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Ian Fleming grad student 1965-1968 Cambridge
Jeremy R. Knowles post-doc 1968-1969 Oxford
Elias James Corey post-doc 1972-1973 Harvard

Children

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Antony John Fairbanks grad student 1990-1993 Oxford
Benjamin G. Davis grad student 1993-1997 Oxford
Martin D. Smith grad student 1995-1999 Oxford
Gangadhar J. Sanjayan post-doc
Tony K. M. Shing post-doc 1982-1984 Oxford
Julio A. Seijas post-doc 1986-1987 Oxford
Ramon J Estevez post-doc 1993-1994
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Publications

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Lu TT, Shimadate Y, Cheng B, et al. (2021) Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives. European Journal of Medicinal Chemistry. 224: 113716
Nash RJ, Bartholomew B, Penkova YB, et al. (2020) Iminosugar idoBR1 Isolated from Cucumber Reduces Inflammatory Activity. Acs Omega. 5: 16263-16271
Kato A, Nakagome I, Hata M, et al. (2020) Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity. Molecules (Basel, Switzerland). 25
Yan X, Shimadate Y, Kato A, et al. (2020) Synthesis of Pyrrolidine Monocyclic Analogues of Pochonicine and Its Stereoisomers: Pursuit ofSimplified Structures and Potent β--Acetylhexosaminidase Inhibition. Molecules (Basel, Switzerland). 25
Yang LF, Shimadate Y, Kato A, et al. (2020) Synthesis and glycosidase inhibition of N-substituted derivatives of 1,4-dideoxy-1,4-imino-d-mannitol (DIM). Organic & Biomolecular Chemistry
Otero JM, Estévez AM, Estévez JC, et al. (2020) Highly functionalized cyclic and bicyclic β−amino acids from sugar β−nitroesters Tetrahedron. 76: 130837
Liu Z, Yoshihara A, Jenkinson SF, et al. (2020) Hanessian-Hullar reaction in the synthesis of highly substituted trans-3,4-dihydroxypyrrolidines: Rhamnulose iminosugar mimics inhibit α-glucosidase Tetrahedron. 76: 130758
Liu Z, Jenkinson SF, Yoshihara A, et al. (2019) d-Idose, d-Iduronic Acid, and d-Idonic Acid from d-Glucose via Seven-Carbon Sugars. Molecules (Basel, Switzerland). 24
Wu QK, Kinami K, Kato A, et al. (2019) Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues. Molecules (Basel, Switzerland). 24
Yoshihara A, Sakoguchi H, Shintani T, et al. (2019) Growth inhibition by 1-deoxy-d-allulose, a novel bioactive deoxy sugar, screened using Caenorhabditis elegans assay. Bioorganic & Medicinal Chemistry Letters
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