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Jeremy R. Knowles

Harvard University, Cambridge, MA, United States 
enzyme catalysis
"Jeremy Knowles"

(1935 - 2008)

Mean distance: 6.39


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Richard O. C. Norman grad student 1959-1961 Oxford
George S. Hammond post-doc 1961-1962 Caltech


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James T. Kadonaga grad student Harvard (FlyTree)
Athel Cornish-Bowden grad student 1965-1967 Oxford
Peter F. Leadlay grad student 1974 Oxford
John A. Gatehouse grad student 1976 Oxford
Joshua Boger grad student 1973-1979 Harvard
Hagan P. Bayley grad student 1974-1979 Harvard
Stephen L. Buchwald grad student 1982 Harvard
Ronald T. Raines grad student 1986 Harvard
Jonathan J. Burbaum grad student 1982-1988 Harvard
Theodore S. Widlanski grad student 1989 Harvard
Stephen C. Blacklow grad student 1991 Harvard
Eugene G. Mueller grad student 1992 Harvard
George Orr post-doc Albert Einstein
David L. Pompliano post-doc Harvard
Martin E. Tanner post-doc Harvard
George W. J. Fleet post-doc 1968-1969 Oxford
James V. Staros post-doc 1974-1977 Harvard
Christopher J. Easton post-doc 1980-1981 Harvard
John Wesley Frost post-doc 1981-1983 Harvard
Andreas Plückthun post-doc 1982-1985 Harvard
Gary D. Glick post-doc 1990 Harvard
Elizabeth A. Komives post-doc 1987-1990 Harvard
Nicole S. Sampson post-doc 1991-1993 Harvard
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Schurig H, Beaucamp N, Ostendorp R, et al. (1995) Phosphoglycerate kinase and triosephosphate isomerase from the hyperthermophilic bacterium Thermotoga maritima form a covalent bifunctional enzyme complex. The Embo Journal. 14: 442-51
Bertolaet BL, Seidel HM, Knowles JR. (1995) Introns and the origin of protein-coding genes. Science (New York, N.Y.). 268: 1367; author reply 1
Seidel HM, Knowles JR. (1994) Interaction of inhibitors with phosphoenolpyruvate mutase: implications for the reaction mechanism and the nature of the active site. Biochemistry. 33: 5641-6
Lodi PJ, Chang LC, Knowles JR, et al. (1994) Triosephosphate isomerase requires a positively charged active site: the role of lysine-12. Biochemistry. 33: 2809-14
Fanuel L, Granier B, Wilkin JM, et al. (1994) The precursor of the Streptomyces R61 DD-peptidase containing a C-terminal extension is inactive. Febs Letters. 351: 49-52
Gallo KA, Knowles JR. (1993) Purification, cloning, and cofactor independence of glutamate racemase from Lactobacillus. Biochemistry. 32: 3981-90
Tanner ME, Gallo KA, Knowles JR. (1993) Isotope effects and the identification of catalytic residues in the reaction catalyzed by glutamate racemase. Biochemistry. 32: 3998-4006
Petsko G, Ringe D, Allen K, et al. (1993) The structural enzymology of proton-transfer reactions Protein Engineering, Design and Selection. 6: 37
Sauter NK, Glick GD, Crowther RL, et al. (1992) Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin. Proceedings of the National Academy of Sciences of the United States of America. 89: 324-8
Seidel HM, Pompliano DL, Knowles JR. (1992) Phosphonate biosynthesis: molecular cloning of the gene for phosphoenolpyruvate mutase from Tetrahymena pyriformis and overexpression of the gene product in Escherichia coli. Biochemistry. 31: 2598-608
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