Geoffrey Wells, PhD
Affiliations: | 1998 | Cancer Research Laboratories, School of Pharmaceutical Sciences | University of Nottingham, Nottingham, England, United Kingdom |
| 1998-2002 | The School of Pharmacy | University of London, London, England, United Kingdom | |
| 2002-2004 | Pharminox Ltd | ||
| 2007- | School of Pharmacy | University College London, London, United Kingdom |
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Parents
Sign in to add mentor| Malcolm F. G. Stevens | grad student | 1998 | Nottingham |
| David E. Thurston | post-doc | 1998-2002 | University College London |
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| Ferguson L, Bhakta S, Fox KR, et al. (2020) Synthesis and Biological Evaluation of a Novel C8-Pyrrolobenzodiazepine (PBD) Adenosine Conjugate. A Study on the Role of the PBD Ring in the Biological Activity of PBD-Conjugates. Molecules (Basel, Switzerland). 25 |
| Ferguson L, Wells G, Bhakta S, et al. (2019) Integrated target-based and phenotypic screening approaches for the identification of anti-tubercular agents that bind to the mycobacterial adenylating enzyme MbtA. Chemmedchem |
| Shih PC, Yang Y, Parkinson GN, et al. (2018) A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3). Oncotarget. 9: 32690-32701 |
| Gacesa R, Lawrence KP, Georgakopoulos ND, et al. (2018) The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 binding. Biochimie |
| Gacesa R, Barlow D, Dunlap W, et al. (2017) Mycosporine-like amino acid activation of the Keap1-Nrf2 pathway Free Radical Biology and Medicine. 108 |
| Kaminska KK, Bertrand HC, Tajima H, et al. (2016) Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads. Oncotarget |
| Schwalbe C, Wells G, Stevens M. (2014) Influence of steric crowding on hydrogen bonding in anti-cancer quinols Acta Crystallographica Section a Foundations and Advances. 70: C561-C561 |
| Brucoli F, Hawkins RM, James CH, et al. (2013) An extended pyrrolobenzodiazepine-polyamide conjugate with selectivity for a DNA sequence containing the ICB2 transcription factor binding site. Journal of Medicinal Chemistry. 56: 6339-51 |
| Hancock R, Schaap M, Pfister H, et al. (2013) Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction with improved binding and cellular activity. Organic & Biomolecular Chemistry. 11: 3553-7 |
| Brucoli F, Hawkins RM, James CH, et al. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters. 21: 3780-3 |