Jeff Gelles, Ph.D.

Biochemistry Brandeis University, Waltham, MA, United States 
Single-molecule biochemistry
"Jeff Gelles"
Mean distance: 8.57


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Sunney I. Chan grad student 1978-1986 Caltech
Michael P. Sheetz post-doc 1986-1989 Washington University


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Laura Finzi grad student Brandeis
Edgar Young grad student Brandeis
Kathleen M. Dohoney grad student 2001 Brandeis
Oi K. Wong grad student 2001 Brandeis
Wei Hua grad student 2002 Brandeis
Jean Pyun grad student 2005 Brandeis
Radhika Subramanian grad student 2007 Brandeis
Todd Thoresen grad student 2007 Brandeis
Harini Ravi grad student 2008 Brandeis
Melisa Osborne grad student 2011 Brandeis
Alvaro Sanchez grad student 2011 Brandeis (Evolution Tree)
Jeffrey P. Bombardier grad student 2015 Brandeis
Hung-Wen Li post-doc Brandeis
Siegfried Musser post-doc Brandeis
Shashank Shekhar post-doc Brandeis (Cell Biology Tree)
Joerg Eberhard Braun post-doc 2012- Brandeis


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Douglas Lowell Theobald collaborator 2010- Brandeis (Evolution Tree)
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Baek I, Friedman LJ, Gelles J, et al. (2021) Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes. Molecular Cell
De Jesus Kim L, Friedman LJ, Looke M, et al. (2021) DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7. Elife. 10
Shekhar S, Hoeprich GJ, Gelles J, et al. (2021) Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization. The Journal of Cell Biology. 220
Rosen GA, Baek I, Friedman LJ, et al. (2020) Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment during activator-dependent transcription. Proceedings of the National Academy of Sciences of the United States of America
Harden TT, Herlambang KS, Chamberlain M, et al. (2020) Alternative transcription cycle for bacterial RNA polymerase. Nature Communications. 11: 448
Shekhar S, Chung J, Kondev J, et al. (2019) Synergy between Cyclase-associated protein and Cofilin accelerates actin filament depolymerization by two orders of magnitude. Nature Communications. 10: 5319
Champasa K, Blank C, Friedman LJ, et al. (2019) A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding. Elife. 8
Huang B, Friedman LJ, Sun M, et al. (2019) Conformational Cycling within the Closed State of Grp94, an Hsp90-Family Chaperone. Journal of Molecular Biology
Stumper SK, Ravi H, Friedman LJ, et al. (2019) Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. Elife. 8
Champasa K, Blank C, Friedman LJ, et al. (2019) Author response: A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding Elife
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