Jeff Gelles, Ph.D.

Affiliations: 
Biochemistry Brandeis University, Waltham, MA, United States 
Area:
Single-molecule biochemistry
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Parents

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Sunney I. Chan grad student 1978-1986 Caltech
Michael P. Sheetz post-doc 1986-1989 Washington University

Children

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Laura Finzi grad student Brandeis
Edgar Young grad student Brandeis
Kathleen M. Dohoney grad student 2001 Brandeis
Oi K. Wong grad student 2001 Brandeis
Wei Hua grad student 2002 Brandeis
Jean Pyun grad student 2005 Brandeis
Radhika Subramanian grad student 2007 Brandeis
Todd Thoresen grad student 2007 Brandeis
Harini Ravi grad student 2008 Brandeis
Melisa Osborne grad student 2011 Brandeis
Alvaro Sanchez grad student 2011 Brandeis (Evolution Tree)
Jeffrey P. Bombardier grad student 2015 Brandeis
Hung-Wen Li post-doc Brandeis
Siegfried Musser post-doc Brandeis
Shashank Shekhar post-doc Brandeis (Cell Biology Tree)
Joerg Eberhard Braun post-doc 2012- Brandeis

Collaborators

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Douglas Lowell Theobald collaborator 2010- Brandeis (Evolution Tree)
BETA: Related publications

Publications

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Champasa K, Blank C, Friedman LJ, et al. (2019) A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding. Elife. 8
Huang B, Friedman LJ, Sun M, et al. (2019) Conformational Cycling within the Closed State of Grp94, an Hsp90-Family Chaperone. Journal of Molecular Biology
Stumper SK, Ravi H, Friedman LJ, et al. (2019) Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. Elife. 8
Braun JE, Friedman LJ, Gelles J, et al. (2018) Synergistic assembly of human pre-spliceosomes across introns and exons. Elife. 7
Ticau S, Friedman LJ, Champasa K, et al. (2017) Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing. Nature Structural & Molecular Biology
Tetone LE, Friedman LJ, Osborne ML, et al. (2017) Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue. Proceedings of the National Academy of Sciences of the United States of America
Chadda R, Krishnamani V, Mersch K, et al. (2016) The dimerization equilibrium of a ClC Cl(-)/H(+) antiporter in lipid bilayers. Elife. 5
Hoskins AA, Rodgers ML, Friedman LJ, et al. (2016) Single molecule analysis reveals reversible and irreversible steps during spliceosome activation. Elife. 5
Harden TT, Wells CD, Friedman LJ, et al. (2016) Bacterial RNA polymerase can retain σ70 throughout transcription. Proceedings of the National Academy of Sciences of the United States of America
Bombardier JP, Eskin JA, Jaiswal R, et al. (2015) Single-molecule visualization of a formin-capping protein 'decision complex' at the actin filament barbed end. Nature Communications. 6: 8707
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