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David A. Horne, Ph.D.

Affiliations: 
1983-1988 Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
 2006- City of Hope and Beckman Research Institute, USA 
Area:
Natural Products, Molecular Medicine
Website:
https://www.cityofhope.org/people/horne-david
Google:
"David Horne"
Bio:

Vice Provost and Associate Director, Beckman Research Institute

Mean distance: 8.01
 

Parents

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George H. Büchi grad student 1983-1988 MIT

Children

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Christian Melander grad student Columbia (Microtree)
Joseph Walter Chihade grad student 1991-1996 Columbia
BETA: Related publications

Publications

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Jana S, Krishna BM, Singhal J, et al. (2020) SOX9: The Master Regulator of Cell Fate in Breast Cancer. Biochemical Pharmacology. 113789
Krishna BM, Jana S, Singhal J, et al. (2019) Notch signaling in breast cancer: From pathway analysis to therapy. Cancer Letters. 461: 123-131
Wen W, Han ES, Dellinger TH, et al. (2019) Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer. Translational Oncology. 12: 1015-1025
Michalak SE, Nam S, Kwon DM, et al. (2019) A Chlorine-Atom-Controlled Terminal-Epoxide-Initiated Bicyclization Cascade Enables a Synthesis of the Potent Cytotoxins Haterumaimides J and K. Journal of the American Chemical Society
Singhal SS, Salgia R, Singhal S, et al. (2019) RLIP: An existential requirement for breast carcinogenesis. Biochimica Et Biophysica Acta. Reviews On Cancer. 1871: 281-288
Nagaprashantha LD, Singhal J, Chikara S, et al. (2018) 2'-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells. Journal of Proteomics
Singhal J, Chikara S, Horne D, et al. (2018) 2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76. Molecular Carcinogenesis
Gu L, Lingeman RG, Yakushijin F, et al. (2018) The anti-cancer activity of a first-in-class small molecule targeting PCNA. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Nagaprashantha LD, Singhal J, Li H, et al. (2018) 2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer. Oncotarget. 9: 18053-18068
Singhal J, Nagaprashantha L, Chikara S, et al. (2017) 2'-Hydroxyflavanone: A novel strategy for targeting breast cancer. Oncotarget. 8: 75025-75037
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