D. Borden Lacy, Ph.D.
Affiliations: | 1990-1994 | University of North Carolina, Chapel Hill, Chapel Hill, NC | |
1994-1999 | University of California, Berkeley, Berkeley, CA | ||
1999- | Vanderbilt University, Nashville, TN |
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"D. Lacy"Mean distance: 8.17 | S | N | B | C | P |
Children
Sign in to add traineeKevin O. Childress | grad student | 2015- | Vanderbilt (Microtree) |
Kelly A. Gangwer | grad student | 2010 | Vanderbilt |
Darren J. Mushrush | grad student | 2011 | Vanderbilt |
Joe Alvin | grad student | 2017 |
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Publications
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Farrow MA, Chumbler NM, Bloch SC, et al. (2020) A small molecule inhibitor screen reveals calcium channel signaling as a mechanistic mediator of Clostridium difficile TcdB-induced necrosis. Acs Chemical Biology |
Chung JM, Sheedlo MJ, Campbell AM, et al. (2019) Structure of the Cag Type IV secretion system. Elife. 8 |
Palmer LD, Jordan AT, Maloney KN, et al. (2019) Zinc intoxication induces ferroptosis in A549 human lung cells. Metallomics : Integrated Biometal Science |
Su M, Erwin AL, Campbell AM, et al. (2019) Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization. Journal of Molecular Biology |
Kroh HK, Chandrasekaran R, Zhang Z, et al. (2017) A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells. The Journal of Biological Chemistry |
Kroh HK, Chandrasekaran R, Rosenthal K, et al. (2017) Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. The Journal of Biological Chemistry |
Alvin JW, Lacy DB. (2017) Clostridium difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue. Journal of Structural Biology. 198: 203-209 |
Hernandez LD, Kroh HK, Hsieh E, et al. (2017) Epitopes and Mechanism of Action of the Clostridium Difficile Toxin A-Neutralizing Antibody Actoxumab. Journal of Molecular Biology |
Norris JL, Farrow MA, Gutierrez DB, et al. (2017) An integrated, high-throughput, multi-omics platform enables data-driven construction of cellular responses and reveals global drug mechanisms of action. Journal of Proteome Research |
Alvin JW, Lacy DB. (2017) Structure Function Studies of Large Clostridial Cytotoxins Toxinology. 1-18 |