D. Borden Lacy, Ph.D.

Affiliations: 
1990-1994 University of North Carolina, Chapel Hill, Chapel Hill, NC 
 1994-1999 University of California, Berkeley, Berkeley, CA 
 1999- Vanderbilt University, Nashville, TN 
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"D. Lacy"
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Parents

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Raymond C. Stevens grad student 1994-1999 UC Berkeley

Children

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Kevin O. Childress grad student 2015- Vanderbilt (Microtree)
Kelly A. Gangwer grad student 2010 Vanderbilt
Darren J. Mushrush grad student 2011 Vanderbilt
Joe Alvin grad student 2017
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Publications

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Farrow MA, Chumbler NM, Bloch SC, et al. (2020) A small molecule inhibitor screen reveals calcium channel signaling as a mechanistic mediator of Clostridium difficile TcdB-induced necrosis. Acs Chemical Biology
Chung JM, Sheedlo MJ, Campbell AM, et al. (2019) Structure of the Cag Type IV secretion system. Elife. 8
Palmer LD, Jordan AT, Maloney KN, et al. (2019) Zinc intoxication induces ferroptosis in A549 human lung cells. Metallomics : Integrated Biometal Science
Su M, Erwin AL, Campbell AM, et al. (2019) Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization. Journal of Molecular Biology
Kroh HK, Chandrasekaran R, Zhang Z, et al. (2017) A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells. The Journal of Biological Chemistry
Kroh HK, Chandrasekaran R, Rosenthal K, et al. (2017) Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. The Journal of Biological Chemistry
Alvin JW, Lacy DB. (2017) Clostridium difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue. Journal of Structural Biology. 198: 203-209
Hernandez LD, Kroh HK, Hsieh E, et al. (2017) Epitopes and Mechanism of Action of the Clostridium Difficile Toxin A-Neutralizing Antibody Actoxumab. Journal of Molecular Biology
Norris JL, Farrow MA, Gutierrez DB, et al. (2017) An integrated, high-throughput, multi-omics platform enables data-driven construction of cellular responses and reveals global drug mechanisms of action. Journal of Proteome Research
Alvin JW, Lacy DB. (2017) Structure Function Studies of Large Clostridial Cytotoxins Toxinology. 1-18
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