D. Borden Lacy, Ph.D.
Affiliations: | 1990-1994 | University of North Carolina, Chapel Hill, Chapel Hill, NC | |
| 1994-1999 | University of California, Berkeley, Berkeley, CA, United States | ||
| 2006- | Vanderbilt University, Nashville, TN |
Area:
Chemistry of bacterial protein toxinsWebsite:
https://www.vumc.org/lacy-labGoogle:
"D. Lacy"Mean distance: 8.17 | S | N | B | C | P |
Parents
Sign in to add mentor| Raymond C. Stevens | grad student | 1994-1999 | UC Berkeley |
| R. John Collier | post-doc | Harvard |
Children
Sign in to add trainee| Kevin O. Childress | grad student | 2015- | Vanderbilt (Microtree) |
| Kelly A. Gangwer | grad student | 2010 | Vanderbilt |
| Darren J. Mushrush | grad student | 2011 | Vanderbilt |
| Joe Alvin | grad student | 2017 | |
| Michael Sheedlo | post-doc | 2016-2021 | Vanderbilt University School of Medicine |
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Publications
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| Siddiqi U, Lunnemann HM, Childress KO, et al. (2024) Inhibition of EGFR/ErbB does not protect against toxin B. Biorxiv : the Preprint Server For Biology |
| Kordus SL, Kroh HK, Rodríguez RC, et al. (2023) Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo. Plos Pathogens. 19: e1011496 |
| Childress KO, Cencer CS, Tyska MJ, et al. (2023) Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for TcdB. Mbio. e0185723 |
| Soto Ocaña J, Bayard NU, Hart JL, et al. (2023) Nonsteroidal anti-inflammatory drugs sensitize epithelial cells to toxin-mediated mitochondrial damage. Science Advances. 9: eadh5552 |
| Peritore-Galve FC, Kaji I, Smith A, et al. (2023) Increased intestinal permeability and downregulation of absorptive ion transporters , , and contribute to diarrhea during infection. Gut Microbes. 15: 2225841 |
| Lacy D, Abhyankar PC. (2023) Dinuclear Mn(I) Complexes with Phosphido and Hydrido Bridges: Synthesis, Reactivity, and Hydrogenative Catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). e202300518 |
| Lunnemann HM, Shealy NG, Reyzer ML, et al. (2023) Cecum axis (CecAx) preservation reveals physiological and pathological gradients in mouse gastrointestinal epithelium. Gut Microbes. 15: 2185029 |
| Castro-Córdova P, Otto-Medina M, Montes-Bravo N, et al. (2022) Redistribution of the Novel Clostridioides difficile Spore Adherence Receptor E-Cadherin by TcdA and TcdB Increases Spore Binding to Adherens Junctions. Infection and Immunity. e0047622 |
| Bernard SC, Washington MK, Lacy DB. (2022) Paeniclostridium sordellii uterine infection is dependent on the estrous cycle. Plos Pathogens. 18: e1010997 |
| Sheedlo MJ, Ohi MD, Lacy DB, et al. (2022) Molecular architecture of bacterial type IV secretion systems. Plos Pathogens. 18: e1010720 |