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Chase L. Beisel - Publications

Affiliations: 
Chemical and biomolecular engineering North Carolina State University, Raleigh, NC 
 2004-2009 Chemical Biology California Institute of Technology, Pasadena, CA 
Website:
https://www.cbe.ncsu.edu/people/cbeisel/
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jiao C, Peeck NL, Yu J, Ghaem Maghami M, Kono S, Collias D, Martinez Diaz SL, Larose R, Beisel CL. TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases. Nature Communications. 15: 5909. PMID 39003282 DOI: 10.1038/s41467-024-50243-x  0.301
2023 Jiao C, Reckstadt C, König F, Homberger C, Yu J, Vogel J, Westermann AJ, Sharma CM, Beisel CL. RNA recording in single bacterial cells using reprogrammed tracrRNAs. Nature Biotechnology. PMID 36604543 DOI: 10.1038/s41587-022-01604-8  0.305
2022 Wu WY, Mohanraju P, Liao C, Adiego-Pérez B, Creutzburg SCA, Makarova KS, Keessen K, Lindeboom TA, Khan TS, Prinsen S, Joosten R, Yan WX, Migur A, Laffeber C, Scott DA, ... ... Beisel CL, et al. The miniature CRISPR-Cas12m effector binds DNA to block transcription. Molecular Cell. PMID 36427491 DOI: 10.1016/j.molcel.2022.11.003  0.313
2022 Wandera KG, Beisel CL. Rapidly Characterizing CRISPR-Cas13 Nucleases Using Cell-Free Transcription-Translation Systems. Methods in Molecular Biology (Clifton, N.J.). 2404: 135-153. PMID 34694607 DOI: 10.1007/978-1-0716-1851-6_7  0.315
2021 Jiao C, Sharma S, Dugar G, Peeck NL, Bischler T, Wimmer F, Yu Y, Barquist L, Schoen C, Kurzai O, Sharma CM, Beisel CL. Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9. Science (New York, N.Y.). PMID 33906967 DOI: 10.1126/science.abe7106  0.302
2021 Collins SP, Rostain W, Liao C, Beisel CL. Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR-Cas12a gRNA switch. Nucleic Acids Research. PMID 33619539 DOI: 10.1093/nar/gkab100  0.31
2020 Collias D, Leenay RT, Slotkowski RA, Zuo Z, Collins SP, McGirr BA, Liu J, Beisel CL. A positive, growth-based PAM screen identifies noncanonical motifs recognized by the Cas9. Science Advances. 6: eabb4054. PMID 32832642 DOI: 10.1126/Sciadv.Abb4054  0.3
2020 Jacobsen T, Yi G, Al Asafen H, Jermusyk AA, Beisel CL, Reeves GT. Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems. Plos One. 15: e0232046. PMID 32352996 DOI: 10.1371/Journal.Pone.0232046  0.342
2020 Jacobsen T, Ttofali F, Liao C, Manchalu S, Gray BN, Beisel CL. Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs. Nucleic Acids Research. PMID 32329776 DOI: 10.1093/Nar/Gkaa272  0.393
2019 Collias D, Marshall R, Collins SP, Beisel CL, Noireaux V. An educational module to explore CRISPR technologies with a cell-free transcription-translation system. Synthetic Biology (Oxford, England). 4: ysz005. PMID 32995532 DOI: 10.1093/Synbio/Ysz005  0.358
2019 Wimmer F, Beisel CL. CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers. Frontiers in Microbiology. 10: 3078. PMID 32038537 DOI: 10.3389/Fmicb.2019.03078  0.32
2019 Liao C, Slotkowski RA, Beisel CL. CRATES: A one-step assembly method for Class 2 CRISPR arrays. Methods in Enzymology. 629: 493-511. PMID 31727255 DOI: 10.1016/Bs.Mie.2019.04.011  0.302
2019 Pickar-Oliver A, Black JB, Lewis MM, Mutchnick KJ, Klann TS, Gilcrest KA, Sitton MJ, Nelson CE, Barrera A, Bartelt LC, Reddy TE, Beisel CL, Barrangou R, Gersbach CA. Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. Nature Biotechnology. PMID 31548729 DOI: 10.1038/S41587-019-0235-7  0.39
2019 Liao C, Ttofali F, Slotkowski RA, Denny SR, Cecil TD, Leenay RT, Keung AJ, Beisel CL. Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis. Nature Communications. 10: 2948. PMID 31270316 DOI: 10.1038/S41467-019-10747-3  0.392
2019 Vento JM, Crook N, Beisel CL. Barriers to genome editing with CRISPR in bacteria. Journal of Industrial Microbiology & Biotechnology. PMID 31165970 DOI: 10.1007/S10295-019-02195-1  0.309
2019 Wandera KG, Collins SP, Wimmer F, Marshall R, Noireaux V, Beisel CL. An enhanced assay to characterize anti-CRISPR proteins using a cell-free transcription-translation system. Methods (San Diego, Calif.). PMID 31121300 DOI: 10.1016/J.Ymeth.2019.05.014  0.312
2019 Jacobsen T, Liao C, Beisel CL. The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs. Fems Microbiology Letters. PMID 31004485 DOI: 10.1093/Femsle/Fnz085  0.334
2019 Westbrook A, Tang X, Marshall R, Maxwell CS, Chappell J, Agrawal DK, Dunlop MJ, Noireaux V, Beisel CL, Lucks J, Franco E. Distinct timescales of RNA regulators enable the construction of a genetic pulse generator. Biotechnology and Bioengineering. PMID 30636320 DOI: 10.1002/Bit.26918  0.422
2018 Beisel CL. CRISPR tool puts RNA on the record. Nature. 562: 347-349. PMID 30323226 DOI: 10.1038/D41586-018-06869-1  0.385
2018 Liao C, Slotkowski RA, Achmedov T, Beisel CL. The Francisella novicida Cas12a is sensitive to the structure downstream of the terminal repeat in CRISPR arrays. Rna Biology. PMID 30252595 DOI: 10.1080/15476286.2018.1526537  0.383
2018 Agrawal DK, Tang X, Westbrook A, Marshall R, Maxwell C, Lucks JB, Noireaux V, Beisel CL, Dunlop M, Franco E. Mathematical modeling of RNA-based architectures for closed loop control of gene expression. Acs Synthetic Biology. PMID 29709170 DOI: 10.1021/Acssynbio.8B00040  0.408
2018 Dugar G, Leenay RT, Eisenbart SK, Bischler T, Aul BU, Beisel CL, Sharma CM. CRISPR RNA-Dependent Binding and Cleavage of Endogenous RNAs by the Campylobacter jejuni Cas9. Molecular Cell. 69: 893-905.e7. PMID 29499139 DOI: 10.1016/J.Molcel.2018.01.032  0.408
2018 Maxwell CS, Jacobsen T, Marshall R, Noireaux V, Beisel CL. A detailed cell-free transcription-translation-based assay to decipher CRISPR protospacer-adjacent motifs. Methods (San Diego, Calif.). PMID 29486239 DOI: 10.1016/J.Ymeth.2018.02.016  0.373
2018 Marshall R, Maxwell CS, Collins SP, Jacobsen T, Luo ML, Begemann MB, Gray BN, January E, Singer A, He Y, Beisel CL, Noireaux V. Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System. Molecular Cell. 69: 146-157.e3. PMID 29304331 DOI: 10.1016/J.Molcel.2017.12.007  0.36
2017 Waller MC, Bober JR, Nair NU, Beisel CL. Toward a genetic tool development pipeline for host-associated bacteria. Current Opinion in Microbiology. 38: 156-164. PMID 28624690 DOI: 10.1016/J.Mib.2017.05.006  0.323
2017 Marshall R, Maxwell CS, Collins SP, Beisel CL, Noireaux V. Short DNA containing χ sites enhances DNA stability and gene expression in E. coli cell-free transcription-translation systems. Biotechnology and Bioengineering. PMID 28475211 DOI: 10.1002/Bit.26333  0.317
2017 Fagen JR, Collias D, Singh AK, Beisel CL. Advancing the design and delivery of CRISPR antimicrobials Current Opinion in Biomedical Engineering. 4: 57-64. DOI: 10.1016/J.Cobme.2017.10.001  0.37
2016 Leenay RT, Beisel CL. Deciphering, communicating, and engineering the CRISPR PAM. Journal of Molecular Biology. PMID 27916599 DOI: 10.1016/J.Jmb.2016.11.024  0.373
2016 Luo ML, Jackson RN, Denny SR, Tokmina-Lukaszewska M, Maksimchuk KR, Lin W, Bothner B, Wiedenheft B, Beisel CL. The CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacers. Nucleic Acids Research. PMID 27174938 DOI: 10.1093/Nar/Gkw421  0.422
2016 Leenay RT, Maksimchuk KR, Slotkowski RA, Agrawal RN, Gomaa AA, Briner AE, Barrangou R, Beisel CL. Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems. Molecular Cell. PMID 27041224 DOI: 10.1016/J.Molcel.2016.02.031  0.317
2015 Luo ML, Leenay RT, Beisel CL. Current and future prospects for CRISPR-based tools in bacteria. Biotechnology and Bioengineering. PMID 26460902 DOI: 10.1002/Bit.25851  0.35
2015 Sun W, Ji W, Hall JM, Hu Q, Wang C, Beisel CL, Gu Z. Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing. Angewandte Chemie (International Ed. in English). PMID 26310292 DOI: 10.1002/Anie.201506030  0.353
2015 Luo ML, Mullis AS, Leenay RT, Beisel CL. Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression. Nucleic Acids Research. 43: 674-81. PMID 25326321 DOI: 10.1093/Nar/Gku971  0.407
2015 Afroz T, Biliouris K, Boykin KE, Kaznessis Y, Beisel CL. Trade-offs in engineering sugar utilization pathways for titratable control. Acs Synthetic Biology. 4: 141-9. PMID 24735079 DOI: 10.1021/Sb400162Z  0.33
2014 Briner AE, Donohoue PD, Gomaa AA, Selle K, Slorach EM, Nye CH, Haurwitz RE, Beisel CL, May AP, Barrangou R. Guide RNA functional modules direct Cas9 activity and orthogonality. Molecular Cell. 56: 333-9. PMID 25373540 DOI: 10.1016/J.Molcel.2014.09.019  0.418
2014 Beisel CL, Bloom RJ, Smolke CD. Construction of ligand-responsive microRNAs that operate through inhibition of Drosha processing. Methods in Molecular Biology (Clifton, N.J.). 1111: 259-67. PMID 24549626 DOI: 10.1007/978-1-62703-755-6_19  0.715
2014 Gomaa AA, Klumpe HE, Luo ML, Selle K, Barrangou R, Beisel CL. Programmable removal of bacterial strains by use of genome-targeting CRISPR-Cas systems. Mbio. 5: e00928-13. PMID 24473129 DOI: 10.1128/Mbio.00928-13  0.406
2013 Afroz T, Beisel CL. Understanding and exploiting feedback in synthetic biology Chemical Engineering Science. 103: 79-90. DOI: 10.1016/J.Ces.2013.02.017  0.343
2012 Beisel CL, Updegrove TB, Janson BJ, Storz G. Multiple factors dictate target selection by Hfq-binding small RNAs. The Embo Journal. 31: 1961-74. PMID 22388518 DOI: 10.1038/Emboj.2012.52  0.732
2011 Beisel CL, Storz G. Discriminating tastes: physiological contributions of the Hfq-binding small RNA Spot 42 to catabolite repression. Rna Biology. 8: 766-70. PMID 21788732 DOI: 10.4161/Rna.8.5.16024  0.639
2011 Beisel CL, Storz G. The base-pairing RNA spot 42 participates in a multioutput feedforward loop to help enact catabolite repression in Escherichia coli. Molecular Cell. 41: 286-97. PMID 21292161 DOI: 10.1016/J.Molcel.2010.12.027  0.635
2011 Enderle D, Beisel C, Stadler MB, Gerstung M, Athri P, Paro R. Polycomb preferentially targets stalled promoters of coding and noncoding transcripts. Genome Research. 21: 216-26. PMID 21177970 DOI: 10.1101/gr.114348.110  0.306
2011 Beisel CL, Chen YY, Culler SJ, Hoff KG, Smolke CD. Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing. Nucleic Acids Research. 39: 2981-94. PMID 21149259 DOI: 10.1093/Nar/Gkq954  0.713
2010 Beisel CL, Storz G. Base pairing small RNAs and their roles in global regulatory networks. Fems Microbiology Reviews. 34: 866-82. PMID 20662934 DOI: 10.1111/J.1574-6976.2010.00241.X  0.603
2009 Beisel CL, Smolke CD. Design principles for riboswitch function. Plos Computational Biology. 5: e1000363. PMID 19381267 DOI: 10.1371/Journal.Pcbi.1000363  0.648
2009 Bayer TS, Hoff KG, Beisel CL, Lee JJ, Smolke CD. Synthetic control of a fitness tradeoff in yeast nitrogen metabolism. Journal of Biological Engineering. 3: 1. PMID 19118500 DOI: 10.1186/1754-1611-3-1  0.696
2008 Beisel CL, Bayer TS, Hoff KG, Smolke CD. Model-guided design of ligand-regulated RNAi for programmable control of gene expression. Molecular Systems Biology. 4: 224. PMID 18956013 DOI: 10.1038/Msb.2008.62  0.744
2008 Beisel CL, Smolke C. How to make an information processing device out of RNA Aiche Annual Meeting, Conference Proceedings.  0.545
2008 Beisel CL, Smolke C. Ligand-responsive micrornas: Toward probing and programming cellular states Aiche Annual Meeting, Conference Proceedings.  0.525
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