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Eric M. Koehn, Ph.D. - Publications

Affiliations: 
Chemistry University of Iowa, Iowa City, IA 
Area:
Enzyme Catalysis
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Koehn EM, Latham JA, Armand T, Evans RL, Tu X, Wilmot CM, Iavarone AT, Klinman JP. Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway. Journal of the American Chemical Society. PMID 30811189 DOI: 10.1021/Jacs.8B13453  0.659
2018 Mondal D, Koehn EM, Yao J, Wiemer DF, Kohen A. Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate. Bioorganic & Medicinal Chemistry. PMID 29606487 DOI: 10.1016/J.Bmc.2018.03.032  0.697
2012 Koehn EM, Perissinotti LL, Moghram S, Prabhakar A, Lesley SA, Mathews II, Kohen A. Folate binding site of flavin-dependent thymidylate synthase Proceedings of the National Academy of Sciences of the United States of America. 109: 15722-15727. PMID 23019356 DOI: 10.1073/Pnas.1206077109  0.701
2012 Mishanina TV, Koehn EM, Conrad JA, Palfey BA, Lesley SA, Kohen A. Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase. Journal of the American Chemical Society. 134: 4442-8. PMID 22295882 DOI: 10.1021/Ja2120822  0.72
2012 Mishanina TV, Koehn EM, Kohen A. Mechanisms and inhibition of uracil methylating enzymes Bioorganic Chemistry. 43: 37-43. PMID 22172597 DOI: 10.1016/J.Bioorg.2011.11.005  0.695
2010 Koehn EM, Kohen A. Flavin-dependent thymidylate synthase: A novel pathway towards thymine Archives of Biochemistry and Biophysics. 493: 96-102. PMID 19643076 DOI: 10.1016/J.Abb.2009.07.016  0.728
2009 Wang Z, Chernyshev A, Koehn EM, Manuel TD, Lesley SA, Kohen A. Oxidase activity of a flavin-dependent thymidylate synthase. The Febs Journal. 276: 2801-10. PMID 19459936 DOI: 10.1111/J.1742-4658.2009.07003.X  0.649
2009 Koehn EM, Fleischmann T, Conrad JA, Palfey BA, Lesley SA, Mathews II, Kohen A. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene Nature. 458: 919-923. PMID 19370033 DOI: 10.1038/Nature07973  0.731
2007 Chernyshev A, Fleischmann T, Koehn EM, Lesley SA, Kohen A. The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS) Chemical Communications. 2861-2863. PMID 17609801 DOI: 10.1039/B700977A  0.676
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