Graham R. Lawton, Ph.D. - Publications
Affiliations: | 2007 | Northwestern University, Evanston, IL |
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical BiologyYear | Citation | Score | |||
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2009 | Silverman RB, Lawton GR, Ranaivo HR, Chico LK, Seo J, Watterson DM. Effect of potential amine prodrugs of selective neuronal nitric oxide synthase inhibitors on blood-brain barrier penetration Bioorganic and Medicinal Chemistry. 17: 7593-7603. PMID 19796958 DOI: 10.1016/J.Bmc.2009.08.065 | 0.573 | |||
2009 | Lawton GR, Ji H, Martásek P, Roman LJ, Silverman RB. Synthesis and enzymatic evaluation of 2- and 4-aminothiazole-based inhibitors of neuronal nitric oxide synthase. Beilstein Journal of Organic Chemistry. 5: 28. PMID 19590740 DOI: 10.3762/Bjoc.5.28 | 0.6 | |||
2009 | Fang J, Ji H, Lawton GR, Xue F, Roman LJ, Silverman RB. L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors Journal of Medicinal Chemistry. 52: 4533-4537. PMID 19537690 DOI: 10.1021/Jm900380J | 0.53 | |||
2009 | Igarashi J, Li H, Jamal J, Ji H, Fang J, Lawton GR, Silverman RB, Poulos TL. Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors. Journal of Medicinal Chemistry. 52: 2060-6. PMID 19296678 DOI: 10.1021/Jm900007A | 0.559 | |||
2009 | Lawton GR, Ralay Ranaivo H, Chico LK, Ji H, Xue F, Martásek P, Roman LJ, Watterson DM, Silverman RB. Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability. Bioorganic & Medicinal Chemistry. 17: 2371-80. PMID 19268602 DOI: 10.1016/J.Bmc.2009.02.017 | 0.623 | |||
2006 | Lawton GR, Ji H, Silverman RB. Remote protection prevents unwanted cyclizations with 2-aminopyridines Tetrahedron Letters. 47: 6113-6115. DOI: 10.1016/J.Tetlet.2006.06.091 | 0.45 | |||
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