| Year |
Citation |
Score |
| 2022 |
Mehrotra S, Lam S, Glenn E, Hymel D, Sanford CA, Liu Q, Herich J, Wulff BS, Meek TH. Unanticipated Characteristics of a Selective, Potent Neuromedin-U Receptor 2 Agonist. Acs Bio & Med Chem Au. 2: 370-375. PMID 37102164 DOI: 10.1021/acsbiomedchemau.2c00016 |
0.309 |
|
| 2022 |
Tsuji K, Hymel D, Ma B, Tamamura H, Nussinov R, Burke TR. Development of ultra-high affinity bivalent ligands targeting the polo-like kinase 1. Rsc Chemical Biology. 3: 1111-1120. PMID 36128509 DOI: 10.1039/d2cb00153e |
0.347 |
|
| 2021 |
Hymel D, Tsuji K, Grant RA, Chingle RM, Kunciw DL, Yaffe MB, Burke TR. Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles. Organic & Biomolecular Chemistry. PMID 34346472 DOI: 10.1039/d1ob01120k |
0.366 |
|
| 2020 |
Tsuji K, Hymel D, Burke TR. A new genre of fluorescence recovery assay to evaluate polo-like kinase 1 ATP-competitive inhibitors. Analytical Methods : Advancing Methods and Applications. 12: 4418-4421. PMID 32970049 DOI: 10.1039/D0Ay01223H |
0.302 |
|
| 2020 |
Qi J, Tsuji K, Hymel D, Burke TR, Hudecek M, Rader C, Peng H. Chemically programmable and switchable CAR-T therapy. Angewandte Chemie (International Ed. in English). PMID 32329959 DOI: 10.1002/Anie.202005432 |
0.456 |
|
| 2019 |
Qi J, Hymel D, Nelson CG, Burke TR, Rader C. Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1. Frontiers in Immunology. 10: 1994. PMID 31497024 DOI: 10.3389/Fimmu.2019.01994 |
0.353 |
|
| 2019 |
Knewtson KE, Perera C, Hymel D, Gao Z, Lee MM, Peterson BR. Antibody-Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome-Disruptive Peptide. Acs Omega. 4: 12955-12968. PMID 31460422 DOI: 10.1021/acsomega.9b01585 |
0.373 |
|
| 2019 |
Zhao XZ, Tsuji K, Hymel D, Burke TR. Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors. Molecules (Basel, Switzerland). 24. PMID 31014020 DOI: 10.3390/Molecules24081488 |
0.453 |
|
| 2018 |
Hymel D, Grant RA, Tsuji K, Yaffe MB, Burke TR. Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 30174151 DOI: 10.1016/J.Bmcl.2018.08.018 |
0.428 |
|
| 2017 |
Nanna AR, Li X, Walseng E, Pedzisa L, Goydel RS, Hymel D, Burke TR, Roush WR, Rader C. Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates. Nature Communications. 8: 1112. PMID 29062027 DOI: 10.1038/S41467-017-01257-1 |
0.412 |
|
| 2017 |
Park JE, Hymel D, Burke TR, Lee KS. Current progress and future perspectives in the development of anti-polo-like kinase 1 therapeutic agents. F1000research. 6: 1024. PMID 28721210 DOI: 10.12688/F1000Research.11398.1 |
0.359 |
|
| 2017 |
Lu X, Nowicka U, Sridharan V, Liu F, Randles L, Hymel D, Dyba M, Tarasov SG, Tarasova NI, Zhao XZ, Hamazaki J, Murata S, Burke TR, Walters KJ. Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets. Nature Communications. 8: 15540. PMID 28598414 DOI: 10.1038/Ncomms15540 |
0.304 |
|
| 2017 |
Li X, Nelson CG, Nair RR, Hazlehurst L, Moroni T, Martinez-Acedo P, Nanna AR, Hymel D, Burke TR, Rader C. Stable and Potent Selenomab-Drug Conjugates. Cell Chemical Biology. PMID 28330604 DOI: 10.1016/J.Chembiol.2017.02.012 |
0.416 |
|
| 2017 |
Zhao XZ, Hymel D, Burke TR. Enhancing polo-like kinase 1 selectivity of polo-box domain-binding peptides. Bioorganic & Medicinal Chemistry. PMID 28285924 DOI: 10.1016/J.Bmc.2017.02.063 |
0.363 |
|
| 2016 |
Hymel D, Burke T. Phosphatase-stable Phosphoamino Acid Mimetics that Enhance Binding Affinities with the Polo-Box Domain of Polo-like Kinase 1. Chemmedchem. PMID 27992122 DOI: 10.1002/Cmdc.201600574 |
0.422 |
|
| 2016 |
Zhao XZ, Hymel D, Burke TR. Application of oxime-diversification to optimize ligand interactions within a cryptic pocket of the polo-like kinase 1 polo-box domain. Bioorganic & Medicinal Chemistry Letters. PMID 27624074 DOI: 10.1016/J.Bmcl.2016.08.098 |
0.382 |
|
| 2015 |
Hymel D, Cai S, Sun Q, Henkhaus RS, Perera C, Peterson BR. Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells. Chemical Communications (Cambridge, England). PMID 26287483 DOI: 10.1039/C5Cc06325F |
0.646 |
|
| 2014 |
Hymel D, Woydziak ZR, Peterson BR. Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores. Journal of the American Chemical Society. 136: 5241-4. PMID 24660775 DOI: 10.1021/Ja501253B |
0.548 |
|
| 2012 |
Hymel D, Peterson BR. Synthetic cell surface receptors for delivery of therapeutics and probes. Advanced Drug Delivery Reviews. 64: 797-810. PMID 22401875 DOI: 10.1016/J.Addr.2012.02.007 |
0.644 |
|
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