| Year |
Citation |
Score |
| 2025 |
Chavali SS, Carman PJ, Shuman H, Ostap EM, Sindelar CV. High-resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory. Proceedings of the National Academy of Sciences of the United States of America. 122: e2415457122. PMID 40014570 DOI: 10.1073/pnas.2415457122 |
0.425 |
|
| 2025 |
Chavali SS, Carman PJ, Shuman H, Ostap EM, Sindelar CV. High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory. Biorxiv : the Preprint Server For Biology. PMID 39829824 DOI: 10.1101/2025.01.10.632429 |
0.425 |
|
| 2024 |
Xu M, Rutkowski DM, Rebowski G, Boczkowska M, Pollard LW, Dominguez R, Vavylonis D, Ostap EM. Myosin-I synergizes with Arp2/3 complex to enhance the pushing forces of branched actin networks. Science Advances. 10: eado5788. PMID 39270022 DOI: 10.1126/sciadv.ado5788 |
0.631 |
|
| 2024 |
Pollard LW, Boczkowska M, Dominguez R, Ostap EM. Myosin-1C differentially displaces tropomyosin isoforms altering their inhibition of motility. The Journal of Biological Chemistry. 300: 107539. PMID 38971309 DOI: 10.1016/j.jbc.2024.107539 |
0.378 |
|
| 2024 |
Xu M, Rutkowski DM, Rebowski G, Boczkowska M, Pollard LW, Dominguez R, Vavylonis D, Ostap EM. Myosin-I Synergizes with Arp2/3 Complex to Enhance Pushing Forces of Branched Actin Networks. Biorxiv : the Preprint Server For Biology. PMID 38405741 DOI: 10.1101/2024.02.09.579714 |
0.632 |
|
| 2023 |
Pedersen RTA, Snoberger A, Pyrpassopoulos S, Safer D, Drubin DG, Ostap EM. Endocytic myosin-1 is a force-insensitive, power-generating motor. The Journal of Cell Biology. 222. PMID 37549220 DOI: 10.1083/jcb.202303095 |
0.366 |
|
| 2023 |
Báez-Cruz FA, Ostap EM. Drosophila class-I myosins that can impact left-right asymmetry have distinct ATPase kinetics. The Journal of Biological Chemistry. 299: 104961. PMID 37380077 DOI: 10.1016/j.jbc.2023.104961 |
0.417 |
|
| 2023 |
Pedersen RT, Snoberger A, Pyrpassopoulos S, Safer D, Drubin DG, Ostap EM. An endocytic myosin essential for plasma membrane invagination powers motility against resistance. Biorxiv : the Preprint Server For Biology. PMID 36993306 DOI: 10.1101/2023.03.21.533689 |
0.36 |
|
| 2023 |
Pollard LW, Coscia SM, Rebowski G, Palmer NJ, Holzbaur ELF, Dominguez R, Ostap EM. Ensembles of human myosin-19 bound to calmodulin and regulatory light chain RLC12B drive multimicron transport. The Journal of Biological Chemistry. 299: 102906. PMID 36642185 DOI: 10.1016/j.jbc.2023.102906 |
0.391 |
|
| 2022 |
Pyrpassopoulos S, Shuman H, Ostap EM. Microtubule Dumbbells to Assess the Effect of Force Geometry on Single Kinesin Motors. Methods in Molecular Biology (Clifton, N.J.). 2478: 559-583. PMID 36063334 DOI: 10.1007/978-1-0716-2229-2_20 |
0.331 |
|
| 2020 |
Bensel BM, Woody MS, Pyrpassopoulos S, Goldman YE, Gilbert SP, Ostap EM. The mechanochemistry of the kinesin-2 KIF3AC heterodimer is related to strain-dependent kinetic properties of KIF3A and KIF3C. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571914 DOI: 10.1073/Pnas.1916343117 |
0.406 |
|
| 2020 |
Pyrpassopoulos S, Shuman H, Ostap EM. Modulation of Kinesin's Load-Bearing Capacity by Force Geometry and the Microtubule Track. Biophysical Journal. 118: 243-253. PMID 31883614 DOI: 10.1016/J.Bpj.2019.10.045 |
0.422 |
|
| 2019 |
Ji HH, Ostap EM. The regulatory protein 14-3-3β binds to the IQ motifs of myosin-IC independently of phosphorylation. The Journal of Biological Chemistry. PMID 31811090 DOI: 10.1074/Jbc.Ra119.011227 |
0.355 |
|
| 2019 |
Woody MS, Winkelmann DA, Capitanio M, Ostap EM, Goldman YE. Single molecule mechanics resolves the earliest events in force generation by cardiac myosin. Elife. 8. PMID 31526481 DOI: 10.7554/Elife.49266 |
0.378 |
|
| 2019 |
Welburn JPI, Ostap EM. Motors in transport and cytoskeleton remodeling. Molecular Biology of the Cell. 30: 734. PMID 30870091 DOI: 10.1091/Mbc.E19-01-0011 |
0.309 |
|
| 2019 |
Lebreton G, Géminard C, Lapraz F, Pyrpassopoulos S, Cerezo D, Spéder P, Ostap EM, Noselli S. Molecular to organismal chirality is induced by the conserved myosin 1D. Science (New York, N.Y.). 362: 949-952. PMID 30467170 DOI: 10.1126/science.aat8642 |
0.319 |
|
| 2019 |
Woody MS, Winkelmann DA, Capitanio M, Ostap EM, Goldman YE. Author response: Single molecule mechanics resolves the earliest events in force generation by cardiac myosin Elife. DOI: 10.7554/Elife.49266.025 |
0.346 |
|
| 2018 |
De La Cruz EM, Blanchoin L, Ostap EM. Opening remarks from the Editors. Biophysical Reviews. 10: 1479-1480. PMID 30488377 DOI: 10.1007/S12551-018-0487-3 |
0.52 |
|
| 2018 |
Woody MS, Greenberg MJ, Barua B, Winkelmann DA, Goldman YE, Ostap EM. Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working stroke. Nature Communications. 9: 3838. PMID 30242219 DOI: 10.1038/S41467-018-06193-2 |
0.375 |
|
| 2018 |
Woody MS, Capitanio M, Ostap EM, Goldman YE. Electro-optic deflectors deliver advantages over acousto-optical deflectors in a high resolution, ultra-fast force-clamp optical trap. Optics Express. 26: 11181-11193. PMID 29716042 DOI: 10.1364/Oe.26.011181 |
0.353 |
|
| 2018 |
Mentes A, Huehn A, Liu X, Zwolak A, Dominguez R, Shuman H, Ostap EM, Sindelar CV. High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358376 DOI: 10.1016/J.Bpj.2017.11.1796 |
0.492 |
|
| 2018 |
McIntosh BB, Pyrpassopoulos S, Holzbaur ELF, Ostap EM. Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal Networks. Current Biology : Cb. PMID 29337076 DOI: 10.1016/J.Cub.2017.12.007 |
0.453 |
|
| 2018 |
Mentes A, Huehn A, Liu X, Zwolak A, Dominguez R, Shuman H, Ostap EM, Sindelar CV. High Resolution Cryo-EM Structures of Actin-Bound Myosin States Reveal the Mechanism of Myosin Force Sensing Biophysical Journal. 114: 319a. DOI: 10.1016/j.bpj.2017.11.1796 |
0.343 |
|
| 2018 |
Woody MS, Greenberg MJ, Barua B, Winkelmann DA, Goldman YE, Ostap EM. Single Molecule, Optical Trapping Studies of Omecamtiv Mercarbil on Human Cardiac Myosin's Force Production Biophysical Journal. 114: 317a-318a. DOI: 10.1016/J.Bpj.2017.11.1787 |
0.318 |
|
| 2017 |
Pyrpassopoulos S, Shuman H, Ostap EM. Adhesion force and attachment lifetime of the KIF16B-PX domain interaction with lipid membranes. Molecular Biology of the Cell. PMID 28931594 DOI: 10.1091/Mbc.E17-05-0324 |
0.414 |
|
| 2017 |
Greenberg MJ, Shuman H, Ostap EM. Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers. Methods in Molecular Biology (Clifton, N.J.). 1486: 483-509. PMID 27844441 DOI: 10.1007/978-1-4939-6421-5_19 |
0.453 |
|
| 2017 |
Pyrpassopoulos S, Shuman H, Ostap EM. A Comparative Single-Molecule Study Between the Mechanical Stability of Kinesin KIF16B Attachment to Lipid Membranes and to Microtubules Biophysical Journal. 112: 427a. DOI: 10.1016/J.Bpj.2016.11.2281 |
0.369 |
|
| 2017 |
McIntosh BB, Holzbaur EL, Ostap EM. Myo1C and Endophilin Promote Kinesin-Driven Tubulation at Engineered Cytoskeletal Intersections Biophysical Journal. 112: 273a. DOI: 10.1016/J.Bpj.2016.11.1480 |
0.445 |
|
| 2017 |
Ostap EM. Molecular Characterization of a Membrane-Associated Cytoskeletal Motor Family Biophysical Journal. 112: 10a-11a. DOI: 10.1016/J.Bpj.2016.11.086 |
0.449 |
|
| 2016 |
Ghiretti AE, Thies E, Tokito MK, Lin T, Ostap EM, Kneussel M, Holzbaur EL. Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B. Neuron. PMID 27817978 DOI: 10.1016/J.Neuron.2016.10.003 |
0.368 |
|
| 2016 |
McIntosh BB, Ostap EM. Myosin-I molecular motors at a glance. Journal of Cell Science. PMID 27401928 DOI: 10.1242/Jcs.186403 |
0.424 |
|
| 2016 |
Greenberg MJ, Arpağ G, Tüzel E, Ostap EM. A Perspective on the Role of Myosins as Mechanosensors. Biophysical Journal. 110: 2568-76. PMID 27332116 DOI: 10.1016/J.Bpj.2016.05.021 |
0.411 |
|
| 2016 |
Pyrpassopoulos S, Arpağ G, Feeser EA, Shuman H, Tüzel E, Ostap EM. Force Generation by Membrane-Associated Myosin-I. Scientific Reports. 6: 25524. PMID 27156719 DOI: 10.1016/J.Bpj.2015.11.2499 |
0.461 |
|
| 2016 |
Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC. An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake. Traffic (Copenhagen, Denmark). 17: 80-1. PMID 26688443 DOI: 10.1111/Tra.12342 |
0.324 |
|
| 2015 |
Kast DJ, Zajac AL, Holzbaur EL, Ostap EM, Dominguez R. WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism. Current Biology : Cb. 25: 1791-7. PMID 26096974 DOI: 10.1016/J.Cub.2015.05.042 |
0.418 |
|
| 2015 |
Greenberg MJ, Lin T, Shuman H, Ostap EM. Mechanochemical tuning of myosin-I by the N-terminal region. Proceedings of the National Academy of Sciences of the United States of America. 112: E3337-44. PMID 26056287 DOI: 10.1073/Pnas.1506633112 |
0.434 |
|
| 2015 |
Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC. An actin filament population defined by the tropomyosin tpm3.1 regulates glucose uptake. Traffic (Copenhagen, Denmark). 16: 691-711. PMID 25783006 DOI: 10.1111/Tra.12282 |
0.373 |
|
| 2015 |
McIntosh BB, Holzbaur EL, Ostap EM. Control of the initiation and termination of kinesin-1-driven transport by myosin-Ic and nonmuscle tropomyosin. Current Biology : Cb. 25: 523-9. PMID 25660542 DOI: 10.1016/J.Cub.2014.12.008 |
0.481 |
|
| 2015 |
Woody MS, Capitanio M, Ostap EM, Goldman YE. Detection of Ultrafast Mechanical Transitions in β-Cardiac Myosin using High-Speed Optical Trapping Biophysical Journal. 108: 301a-302a. DOI: 10.1016/J.Bpj.2014.11.1640 |
0.463 |
|
| 2015 |
Greenberg MJ, Lin T, Shuman H, Ostap EM. Structural Determinants of Myosin I Mechanosensing: The N Terminal Region Biophysical Journal. 108: 25a. DOI: 10.1016/J.Bpj.2014.11.162 |
0.481 |
|
| 2014 |
Greenberg MJ, Shuman H, Ostap EM. Inherent force-dependent properties of β-cardiac myosin contribute to the force-velocity relationship of cardiac muscle. Biophysical Journal. 107: L41-4. PMID 25517169 DOI: 10.1016/J.Bpj.2014.11.005 |
0.372 |
|
| 2014 |
Ayloo S, Lazarus JE, Dodda A, Tokito M, Ostap EM, Holzbaur EL. Dynactin functions as both a dynamic tether and brake during dynein-driven motility. Nature Communications. 5: 4807. PMID 25185702 DOI: 10.1038/Ncomms5807 |
0.429 |
|
| 2014 |
Shuman H, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Dominguez R, Ostap EM. A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning. Proceedings of the National Academy of Sciences of the United States of America. 111: 2116-21. PMID 24469830 DOI: 10.1073/Pnas.1321022111 |
0.315 |
|
| 2014 |
Hendricks AG, Beausang JF, Lewis JH, Lippert L, Shroder D, Ostap EM, Holzbaur EL, Goldman YE. New Methods for Molecular Motor and Cell Motility Research Biophysical Journal. 106: 232a-233a. DOI: 10.1016/J.Bpj.2013.11.1362 |
0.41 |
|
| 2014 |
Ostap EM, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Goldman YE, Dominguez R, Shuman H. Structural, Mechanical, and Biochemical Insights into the Mechanism of Myosin Force Sensing Biophysical Journal. 106: 10a. DOI: 10.1016/J.Bpj.2013.11.101 |
0.464 |
|
| 2014 |
Greenberg MJ, Shuman H, Zwolak A, Sindelar C, Dominguez R, Ostap EM. The Structure of Vertebrate Myosin-I Reveals New Insights into Mechanochemical Tuning of Myosins Biophysical Journal. 106: 178a. DOI: 10.1016/J.Bpj.2013.11.1006 |
0.489 |
|
| 2013 |
Zwolak A, Yang C, Feeser EA, Ostap EM, Svitkina T, Dominguez R. CARMIL leading edge localization depends on a non-canonical PH domain and dimerization. Nature Communications. 4: 2523. PMID 24071777 DOI: 10.1038/Ncomms3523 |
0.341 |
|
| 2013 |
Pyrpassopoulos S, Shuman H, Ostap EM. Method for measuring single-molecule adhesion forces and attachment lifetimes of protein-membrane interactions. Methods in Molecular Biology (Clifton, N.J.). 1046: 389-403. PMID 23868602 DOI: 10.1007/978-1-62703-538-5_24 |
0.378 |
|
| 2013 |
Zajac AL, Goldman YE, Holzbaur EL, Ostap EM. Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Current Biology : Cb. 23: 1173-80. PMID 23770188 DOI: 10.1016/J.Cub.2013.05.015 |
0.38 |
|
| 2013 |
Greenberg MJ, Ostap EM. Regulation and control of myosin-I by the motor and light chain-binding domains. Trends in Cell Biology. 23: 81-9. PMID 23200340 DOI: 10.1016/J.Tcb.2012.10.008 |
0.418 |
|
| 2013 |
Zajac AL, Goldman YE, Holzbaur EL, Ostap EM. High-Resolution Imaging of Endocytosed EGF-Quantum Dots Reveals Cellular Factors Regulating the Transitions between the Directed and Diffusive Movement of Early Endosomes Biophysical Journal. 104: 651a-652a. DOI: 10.1016/J.Bpj.2012.11.3598 |
0.308 |
|
| 2013 |
Pyrpassopoulos S, Shuman H, Ostap EM. Force Generation by Membrane-Bound Myo1c, a Single Molecule Study Biophysical Journal. 104: 642a. DOI: 10.1016/J.Bpj.2012.11.3547 |
0.423 |
|
| 2012 |
Dawicki-McKenna JM, Goldman YE, Ostap EM. Sites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubules. Plos One. 7: e43662. PMID 22916292 DOI: 10.1371/Journal.Pone.0043662 |
0.348 |
|
| 2012 |
Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM. Myosin IC generates power over a range of loads via a new tension-sensing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: E2433-40. PMID 22908250 DOI: 10.1073/Pnas.1207811109 |
0.479 |
|
| 2012 |
Pyrpassopoulos S, Feeser EA, Mazerik JN, Tyska MJ, Ostap EM. Membrane-bound myo1c powers asymmetric motility of actin filaments. Current Biology : Cb. 22: 1688-92. PMID 22863317 DOI: 10.1016/J.Cub.2012.06.069 |
0.473 |
|
| 2012 |
Lewis JH, Greenberg MJ, Laakso JM, Shuman H, Ostap EM. Calcium regulation of myosin-I tension sensing. Biophysical Journal. 102: 2799-807. PMID 22735530 DOI: 10.1016/J.Bpj.2012.05.014 |
0.433 |
|
| 2012 |
Chen C, Greenberg MJ, Laakso JM, Ostap EM, Goldman YE, Shuman H. Kinetic schemes for post-synchronized single molecule dynamics. Biophysical Journal. 102: L23-5. PMID 22455931 DOI: 10.1016/J.Bpj.2012.01.054 |
0.319 |
|
| 2012 |
Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM. Myo1c is Built for Sustained Power Under Load, not Tension Sensing Biophysical Journal. 102: 566a. DOI: 10.1016/J.Bpj.2011.11.3085 |
0.415 |
|
| 2012 |
Hendricks AG, Zajac AL, Schroeder HW, Maday S, Ostap EM, Goldman YE, Holzbaur EL. Coordination of Multiple Motors Bound to Intracellular Cargos Biophysical Journal. 102: 213a. DOI: 10.1016/J.Bpj.2011.11.1165 |
0.416 |
|
| 2011 |
Lin T, Greenberg MJ, Moore JR, Ostap EM. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity. Biochemistry. 50: 1831-8. PMID 21265502 DOI: 10.1021/Bi1016777 |
0.424 |
|
| 2011 |
Shuman H, Laakso JM, Ostap EM. Conformational Dynamics of Nucleotide-Free Myo1b Biophysical Journal. 100: 116a. DOI: 10.1016/J.Bpj.2010.12.840 |
0.408 |
|
| 2011 |
McKenna JMD, Goldman YE, Ostap EM. Spatial Organization of Microtubules Specifies Sites of Glucose Transporter-4 Vesicle Fusion with the Plasma Membrane Biophysical Journal. 100: 409a. DOI: 10.1016/J.Bpj.2010.12.2425 |
0.333 |
|
| 2010 |
Pyrpassopoulos S, Shuman H, Ostap EM. Single-molecule adhesion forces and attachment lifetimes of myosin-I phosphoinositide interactions. Biophysical Journal. 99: 3916-22. PMID 21156133 DOI: 10.1016/J.Bpj.2010.10.043 |
0.447 |
|
| 2010 |
Feeser EA, Ignacio CM, Krendel M, Ostap EM. Myo1e binds anionic phospholipids with high affinity. Biochemistry. 49: 9353-60. PMID 20860408 DOI: 10.1021/Bi1012657 |
0.429 |
|
| 2010 |
Laakso JM, Lewis JH, Shuman H, Ostap EM. Control of myosin-I force sensing by alternative splicing Proceedings of the National Academy of Sciences of the United States of America. 107: 698-702. PMID 20080738 DOI: 10.1073/Pnas.0911426107 |
0.494 |
|
| 2010 |
Patino-Lopez G, Aravind L, Dong X, Kruhlak MJ, Ostap EM, Shaw S. Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH). The Journal of Biological Chemistry. 285: 8675-86. PMID 20071333 DOI: 10.1074/Jbc.M109.086959 |
0.379 |
|
| 2010 |
Pyrpassopoulos S, Shuman H, Ostap EM. Kinetics of Myosin-I-Membrane Detachment Under Load Biophysical Journal. 98: 562a. DOI: 10.1016/J.Bpj.2009.12.3044 |
0.45 |
|
| 2010 |
Lewis JH, Laakso J, Lin T, Shuman H, Ostap EM. Calcium Regulation of myo1b Tension Sensing Biophysical Journal. 98: 229a. DOI: 10.1016/J.Bpj.2009.12.1238 |
0.4 |
|
| 2009 |
McKenna JM, Ostap EM. Kinetics of the interaction of myo1c with phosphoinositides. The Journal of Biological Chemistry. 284: 28650-9. PMID 19706607 DOI: 10.1074/Jbc.M109.049791 |
0.437 |
|
| 2009 |
Bethoney KA, King MC, Hinshaw JE, Ostap EM, Lemmon MA. A possible effector role for the pleckstrin homology (PH) domain of dynamin. Proceedings of the National Academy of Sciences of the United States of America. 106: 13359-64. PMID 19666604 DOI: 10.1073/Pnas.0906945106 |
0.368 |
|
| 2009 |
Sun Y, McKenna JD, Murray JM, Ostap EM, Goldman YE. Parallax: high accuracy three-dimensional single molecule tracking using split images. Nano Letters. 9: 2676-82. PMID 19496608 DOI: 10.1021/Nl901129J |
0.33 |
|
| 2009 |
De La Cruz EM, Ostap EM. Kinetic and equilibrium analysis of the myosin ATPase. Methods in Enzymology. 455: 157-92. PMID 19289206 DOI: 10.1016/S0076-6879(08)04206-7 |
0.684 |
|
| 2009 |
Dawicki McKenna JM, Ostap EM. Kinetics Of Myo1c Association To And Dissociation From Phosphoinositide-containing Vesicles Biophysical Journal. 96: 139a. DOI: 10.1016/J.Bpj.2008.12.3870 |
0.363 |
|
| 2009 |
Pyrpassopoulos S, Shuman H, Ostap EM. Single-molecule Measurements Of Myo1c-PIP2 Detachment Forces Using Optical Tweezers Biophysical Journal. 96: 139a. DOI: 10.1016/J.Bpj.2008.12.3867 |
0.454 |
|
| 2009 |
Laakso JM, Shuman H, Ostap EM. Force Dependence of a Myo1b Truncation Mutant Biophysical Journal. 96: 138a-139a. DOI: 10.1016/J.Bpj.2008.12.3866 |
0.437 |
|
| 2008 |
Ostap EM. Tropomyosins as discriminators of myosin function. Advances in Experimental Medicine and Biology. 644: 273-82. PMID 19209828 DOI: 10.1007/978-0-387-85766-4_20 |
0.414 |
|
| 2008 |
Laakso JM, Lewis JH, Shuman H, Ostap EM. Myosin I can act as a molecular force sensor Science. 321: 133-136. PMID 18599791 DOI: 10.1126/Science.1159419 |
0.465 |
|
| 2007 |
Tang N, Lin T, Yang J, Foskett JK, Ostap EM. CIB1 and CaBP1 bind to the myo1c regulatory domain. Journal of Muscle Research and Cell Motility. 28: 285-91. PMID 17994197 DOI: 10.1007/S10974-007-9124-7 |
0.394 |
|
| 2007 |
Manceva S, Lin T, Pham H, Lewis JH, Goldman YE, Ostap EM. Calcium regulation of calmodulin binding to and dissociation from the myo1c regulatory domain. Biochemistry. 46: 11718-26. PMID 17910470 DOI: 10.1021/Bi700894H |
0.417 |
|
| 2007 |
Bach TL, Kerr WT, Wang Y, Bauman EM, Kine P, Whiteman EL, Morgan RS, Williamson EK, Ostap EM, Burkhardt JK, Koretzky GA, Birnbaum MJ, Abrams CS. PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. Blood. 109: 1147-55. PMID 17008542 DOI: 10.1182/Blood-2006-02-001339 |
0.379 |
|
| 2006 |
Lewis JH, Lin T, Hokanson DE, Ostap EM. Temperature dependence of nucleotide association and kinetic characterization of myo1b. Biochemistry. 45: 11589-97. PMID 16981718 DOI: 10.1021/Bi0611917 |
0.431 |
|
| 2006 |
Hokanson DE, Laakso JM, Lin T, Sept D, Ostap EM. Myo1c binds phosphoinositides through a putative pleckstrin homology domain. Molecular Biology of the Cell. 17: 4856-65. PMID 16971510 DOI: 10.1091/Mbc.E06-05-0449 |
0.409 |
|
| 2006 |
Hokanson DE, Ostap EM. Myo1c binds tightly and specifically to phosphatidylinositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate. Proceedings of the National Academy of Sciences of the United States of America. 103: 3118-23. PMID 16492791 DOI: 10.1073/Pnas.0505685103 |
0.448 |
|
| 2005 |
Lin T, Tang N, Ostap EM. Biochemical and motile properties of Myo1b splice isoforms. The Journal of Biological Chemistry. 280: 41562-7. PMID 16254000 DOI: 10.1074/Jbc.M508653200 |
0.457 |
|
| 2004 |
De La Cruz EM, Ostap EM. Relating biochemistry and function in the myosin superfamily. Current Opinion in Cell Biology. 16: 61-7. PMID 15037306 DOI: 10.1016/J.Ceb.2003.11.011 |
0.65 |
|
| 2003 |
Shaw MA, Ostap EM, Goldman YE. Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry. 42: 6128-35. PMID 12755615 DOI: 10.1021/Bi026964F |
0.435 |
|
| 2003 |
Ostap EM, Maupin P, Doberstein SK, Baines IC, Korn ED, Pollard TD. Dynamic localization of myosin-I to endocytic structures in Acanthamoeba. Cell Motility and the Cytoskeleton. 54: 29-40. PMID 12451593 DOI: 10.1002/Cm.10081 |
0.677 |
|
| 2002 |
Ostap EM. 2,3-Butanedione monoxime (BDM) as a myosin inhibitor. Journal of Muscle Research and Cell Motility. 23: 305-8. PMID 12630704 DOI: 10.1023/A:1022047102064 |
0.398 |
|
| 2002 |
Ostap EM, Lin T, Rosenfeld SS, Tang N. Mechanism of regulation of Acanthamoeba myosin-IC by heavy-chain phosphorylation. Biochemistry. 41: 12450-6. PMID 12369835 DOI: 10.1021/Bi0262193 |
0.51 |
|
| 2002 |
Tang N, Lin T, Ostap EM. Dynamics of myo1c (myosin-ibeta ) lipid binding and dissociation. The Journal of Biological Chemistry. 277: 42763-8. PMID 12221091 DOI: 10.1074/Jbc.M206388200 |
0.422 |
|
| 2002 |
Yengo CM, De la Cruz EM, Safer D, Ostap EM, Sweeney HL. Kinetic characterization of the weak binding states of myosin V. Biochemistry. 41: 8508-17. PMID 12081502 DOI: 10.1021/Bi015969U |
0.677 |
|
| 2002 |
El Mezgueldi M, Tang N, Rosenfeld SS, Ostap EM. The kinetic mechanism of Myo1e (human myosin-IC). The Journal of Biological Chemistry. 277: 21514-21. PMID 11940582 DOI: 10.1074/Jbc.M200713200 |
0.505 |
|
| 2001 |
Gillespie PG, Albanesi JP, Bahler M, Bement WM, Berg JS, Burgess DR, Burnside B, Cheney RE, Corey DP, Coudrier E, de Lanerolle P, Hammer JA, Hasson T, Holt JR, Hudspeth AJ, ... ... Ostap EM, et al. Myosin-I nomenclature. The Journal of Cell Biology. 155: 703-4. PMID 11724811 DOI: 10.1083/Jcb.200110032 |
0.671 |
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| 2001 |
Tang N, Ostap EM. Motor domain-dependent localization of myo1b (myr-1). Current Biology : Cb. 11: 1131-5. PMID 11509238 DOI: 10.1016/S0960-9822(01)00320-7 |
0.487 |
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| 2001 |
De La Cruz EM, Ostap EM, Sweeney HL. Kinetic mechanism and regulation of myosin VI. The Journal of Biological Chemistry. 276: 32373-81. PMID 11423557 DOI: 10.1074/Jbc.M104136200 |
0.7 |
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| 2000 |
De La Cruz EM, Wells AL, Sweeney HL, Ostap EM. Actin and light chain isoform dependence of myosin V kinetics. Biochemistry. 39: 14196-202. PMID 11087368 DOI: 10.1021/Bi001701B |
0.654 |
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| 2000 |
De La Cruz EM, Sweeney HL, Ostap EM. ADP inhibition of myosin V ATPase activity. Biophysical Journal. 79: 1524-9. PMID 10969013 DOI: 10.1016/S0006-3495(00)76403-4 |
0.671 |
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| 2000 |
De La Cruz EM, Ostap EM, Brundage RA, Reddy KS, Sweeney HL, Safer D. Thymosin-beta(4) changes the conformation and dynamics of actin monomers. Biophysical Journal. 78: 2516-27. PMID 10777749 DOI: 10.1016/S0006-3495(00)76797-X |
0.684 |
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| 1999 |
Lee WL, Ostap EM, Zot HG, Pollard TD. Organization and ligand binding properties of the tail of Acanthamoeba myosin-IA. Identification of an actin-binding site in the basic (tail homology-1) domain. The Journal of Biological Chemistry. 274: 35159-71. PMID 10574999 DOI: 10.1074/Jbc.274.49.35159 |
0.664 |
|
| 1999 |
De La Cruz EM, Wells AL, Rosenfeld SS, Ostap EM, Sweeney HL. The kinetic mechanism of myosin V. Proceedings of the National Academy of Sciences of the United States of America. 96: 13726-31. PMID 10570140 DOI: 10.1073/Pnas.96.24.13726 |
0.7 |
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| 1998 |
Jontes JD, Ostap EM, Pollard TD, Milligan RA. Three-dimensional structure of Acanthamoeba castellanii myosin-IB (MIB) determined by cryoelectron microscopy of decorated actin filaments. The Journal of Cell Biology. 141: 155-62. PMID 9531555 DOI: 10.1083/Jcb.141.1.155 |
0.603 |
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| 1997 |
Jontes JD, Milligan RA, Pollard TD, Ostap EM. Kinetic characterization of brush border myosin-I ATPase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14332-7. PMID 9405612 DOI: 10.1073/pnas.94.26.14332 |
0.532 |
|
| 1996 |
Pollard TD, Ostap EM. The chemical mechanism of myosin-I: implications for actin-based motility and the evolution of the myosin family of motor proteins. Cell Structure and Function. 21: 351-6. PMID 9118240 DOI: 10.1247/Csf.21.351 |
0.668 |
|
| 1996 |
Ostap EM, Pollard TD. Overlapping functions of myosin-I isoforms? The Journal of Cell Biology. 133: 221-4. PMID 8609156 DOI: 10.1083/Jcb.133.2.221 |
0.464 |
|
| 1996 |
Ostap EM, Pollard TD. Biochemical kinetic characterization of the Acanthamoeba myosin-I ATPase. The Journal of Cell Biology. 132: 1053-60. PMID 8601584 DOI: 10.1083/Jcb.132.6.1053 |
0.624 |
|
| 1995 |
Thomas DD, Ramachandran S, Roopnarine O, Hayden DW, Ostap EM, Rayment I, Reisler K, Kinosita K. The mechanism of force generation in myosin: A disorder-to-order transition, coupled to internal structural changes Biophysical Journal. 68: 135s-141s. PMID 7787056 |
0.342 |
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| 1993 |
Ostap EM, White HD, Thomas DD. Transient detection of spin-labeled myosin subfragment 1 conformational states during ATP hydrolysis. Biochemistry. 32: 6712-20. PMID 8392368 DOI: 10.1021/Bi00077A026 |
0.371 |
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| Low-probability matches (unlikely to be authored by this person) |
| 1995 |
Ostap EM, Barnett VA, Thomas DD. Resolution of three structural states of spin-labeled myosin in contracting muscle. Biophysical Journal. 69: 177-88. PMID 7669895 DOI: 10.1016/S0006-3495(95)79888-5 |
0.297 |
|
| 1991 |
Ostap EM, Thomas DD. Rotational dynamics of spin-labeled F-actin during activation of myosin S1 ATPase using caged ATP. Biophysical Journal. 59: 1235-41. PMID 1651780 DOI: 10.1016/S0006-3495(91)82338-4 |
0.297 |
|
| 2022 |
Gardini L, Woody MS, Kashchuk AV, Goldman YE, Ostap EM, Capitanio M. High-Speed Optical Traps Address Dynamics of Processive and Non-Processive Molecular Motors. Methods in Molecular Biology (Clifton, N.J.). 2478: 513-557. PMID 36063333 DOI: 10.1007/978-1-0716-2229-2_19 |
0.295 |
|
| 2012 |
Goldman YE, Ostap EM. Myosin motors: Kinetics of myosin Comprehensive Biophysics. 4: 151-169. DOI: 10.1016/B978-0-12-374920-8.00411-2 |
0.289 |
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| 2023 |
Pyrpassopoulos S, Gicking AM, Zaniewski TM, Hancock WO, Ostap EM. KIF1A is kinetically tuned to be a superengaging motor under hindering loads. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216903120. PMID 36598948 DOI: 10.1073/pnas.2216903120 |
0.282 |
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| 2019 |
Mentes A, Shuman H, Ostap EM. State Dependent Dynamic Coupling in Myo1B During the Force Sensitive Transition and MgADP Release Biophysical Journal. 116: 260a. DOI: 10.1016/J.Bpj.2018.11.1415 |
0.282 |
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| 2021 |
Masucci EM, Relich PK, Lakadamyali M, Ostap EM, Holzbaur ELF. Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites. Molecular Biology of the Cell. mbcE21100480. PMID 34705476 DOI: 10.1091/mbc.E21-10-0480 |
0.273 |
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| 2017 |
Lewis JH, Jamiolkowski RM, Woody MS, Ostap EM, Goldman YE. Deconvolution of Camera Instrument Response Functions. Biophysical Journal. 112: 1214-1220. PMID 28355548 DOI: 10.1016/J.Bpj.2017.02.014 |
0.272 |
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| 2020 |
Snoberger A, Winkelmann DA, Ostap EM, Goldman YE. Buffer Exchange while Probing a Single Actomyosin Interaction in the Optical Trap Biophysical Journal. 118: 436a. DOI: 10.1016/J.Bpj.2019.11.2445 |
0.252 |
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| 2021 |
Snoberger A, Barua B, Atherton JL, Shuman H, Forgacs E, Goldman YE, Winkelmann DA, Ostap EM. Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil. Elife. 10. PMID 33605878 DOI: 10.7554/eLife.63691 |
0.244 |
|
| 2023 |
Coscia SM, Thompson CP, Tang Q, Baltrusaitis EE, Rhodenhiser JA, Quintero-Carmona OA, Ostap EM, Lakadamyali M, Holzbaur ELF. Myo19 tethers mitochondria to endoplasmic reticulum-associated actin to promote mitochondrial fission. Journal of Cell Science. PMID 36744380 DOI: 10.1242/jcs.260612 |
0.244 |
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| 2020 |
Snoberger A, Barua B, Atherton JL, Forgacs E, Goldman YE, Winkelmann DA, Ostap EM. Beta-Cardiac Myosin with an HCM Mutation (R712L) has an Inhibited Working Stroke that is Rescued by the Drug Omecamtiv Mecarbil Biophysical Journal. 118: 177a. DOI: 10.1016/J.Bpj.2019.11.1082 |
0.239 |
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| 2017 |
Mentes A, Shuman H, Ostap EM. Molecular Dynamics and Normal Mode Analysis of Myo1b and Myo1b Deletion Constructs Reveal Coupling between the Lever Arm Helix, N-Terminus, and Active Site Biophysical Journal. 112: 265a-266a. DOI: 10.1016/J.Bpj.2016.11.1441 |
0.234 |
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| 2018 |
Ji H, Ostap EM. Biochemical and Functional Characterization of the Interaction of Myo1c with 14-3-3 Biophysical Journal. 114: 318a. DOI: 10.1016/J.Bpj.2017.11.1790 |
0.234 |
|
| 1992 |
Ostap EM, Yanagida T, Thomas DD. Orientational distribution of spin-labeled actin oriented by flow. Biophysical Journal. 63: 966-75. PMID 1330042 DOI: 10.1016/S0006-3495(92)81684-3 |
0.233 |
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| 2015 |
Kast DJ, Zajac AL, Holzbaur ELF, Ostap EM, Dominguez R. WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism Current Biology. DOI: 10.1016/j.cub.2015.05.042 |
0.225 |
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| 2025 |
Cail RC, Baez-Cruz FA, Winkelmann DA, Goldman YE, Ostap EM. Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states. The Journal of Biological Chemistry. 108412. PMID 40118457 DOI: 10.1016/j.jbc.2025.108412 |
0.223 |
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| 2016 |
Woody MS, Lewis JH, Greenberg MJ, Goldman YE, Ostap EM. Accessible, Feature-Rich Software for Rigorous Model Fitting using Maximum Likelihood Estimation Biophysical Journal. 110: 331a. DOI: 10.1016/J.Bpj.2015.11.1778 |
0.213 |
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| 2016 |
Woody MS, Lewis JH, Greenberg MJ, Goldman YE, Ostap EM. MEMLET: An Easy-to-Use Tool for Data Fitting and Model Comparison Using Maximum-Likelihood Estimation. Biophysical Journal. 111: 273-282. PMID 27463130 DOI: 10.1016/J.Bpj.2016.06.019 |
0.21 |
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| 2024 |
Ceron RH, Báez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R. Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy. Science Advances. 10: eadn6615. PMID 38820162 DOI: 10.1126/sciadv.adn6615 |
0.201 |
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| 2020 |
Bensel BM, Woody MS, Pyrpassopoulos S, Goldman YE, Gilbert SP, Ostap EM. Strain-Dependent Properties of KIF3A and KIF3C Tune the Mechanochemistry of the KIF3AC Heterodimer Biophysical Journal. 118: 429a-430a. DOI: 10.1016/J.Bpj.2019.11.2415 |
0.189 |
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| 2022 |
Pyrpassopoulos S, Shuman H, Ostap EM. Modulation of Kinesin's Load-Bearing Capacity by Force Geometry and the Microtubule Track. Biophysical Journal. 121: 4748. PMID 36455557 DOI: 10.1016/j.bpj.2022.11.2939 |
0.183 |
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| 2024 |
Coscia SM, Moore AS, Thompson CP, Tirrito CF, Ostap EM, Holzbaur ELF. An interphase actin wave promotes mitochondrial content mixing and organelle homeostasis. Nature Communications. 15: 3793. PMID 38714822 DOI: 10.1038/s41467-024-48189-1 |
0.167 |
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| 1993 |
Naber N, Ostap EM, Thomas DD, Cooke R. Orientation and rotational dynamics of spin-labeled phalloidin bound to actin in muscle fibers. Proteins. 17: 347-54. PMID 8108377 DOI: 10.1002/prot.340170403 |
0.151 |
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| 2022 |
Day SM, Tardiff JC, Ostap EM. Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure. The Journal of Clinical Investigation. 132. PMID 35229734 DOI: 10.1172/JCI148557 |
0.136 |
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| 2025 |
Cail RC, Barua B, Báez-Cruz FA, Winkelmann DA, Goldman YE, Ostap EM. A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment. Biorxiv : the Preprint Server For Biology. PMID 40501550 DOI: 10.1101/2025.06.02.657466 |
0.12 |
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| 2012 |
Pyrpassopoulos S, Feeser EA, Ostap E. Asymmetric Motility Powered by Myo1c on Lipid Membranes Biophysical Journal. 102: 566a. DOI: 10.1016/j.bpj.2011.11.3084 |
0.114 |
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| 2021 |
Masucci EM, Relich PK, Ostap EM, Holzbaur ELF, Lakadamyali M. Cega: A Single Particle Segmentation Algorithm to Identify Moving Particles in a Noisy System. Molecular Biology of the Cell. mbcE20110744. PMID 33788586 DOI: 10.1091/mbc.E20-11-0744 |
0.105 |
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| 2012 |
Goldman YE, Ostap EM. Introduction Comprehensive Biophysics. 4: 1-1. DOI: 10.1016/B978-0-12-374920-8.00401-X |
0.014 |
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| Hide low-probability matches. |