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David Dale Thomas - Publications

Affiliations: 
1979- Biochemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Structural Biology
Website:
https://cbs.umn.edu/contacts/david-d-thomas
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Year Citation  Score
2023 Roopnarine O, Thomas DD. Structural Dynamics of Protein Interactions Using Site-Directed Spin Labeling of Cysteines to Measure Distances and Rotational Dynamics with EPR Spectroscopy. Applied Magnetic Resonance. 55: 79-100. PMID 38371230 DOI: 10.1007/s00723-023-01623-x  0.761
2023 Bovo E, Rebbeck RT, Roopnarine O, Cornea RL, Thomas DD, Zima AV. Regulation of cardiac calcium signaling by newly identified calcium pump modulators. Biochemical and Biophysical Research Communications. 685: 149136. PMID 37907012 DOI: 10.1016/j.bbrc.2023.149136  0.727
2023 Šeflová J, Schwarz JA, Smith AN, Svensson B, Blackwell DJ, Phillips TA, Nikolaienko R, Bovo E, Rebbeck RT, Zima AV, Thomas DD, Van Petegem F, Knollmann BC, Johnston JN, Robia SL, et al. RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET. Acs Chemical Biology. PMID 37769131 DOI: 10.1021/acschembio.3c00376  0.641
2023 Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators. Scientific Reports. 13: 10673. PMID 37393380 DOI: 10.1038/s41598-023-37704-x  0.801
2023 Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators. Research Square. PMID 36909610 DOI: 10.21203/rs.3.rs-2596384/v1  0.73
2023 Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators. Biorxiv : the Preprint Server For Biology. PMID 36865289 DOI: 10.1101/2023.02.22.529557  0.794
2023 Ernst P, Bidwell PA, Dora M, Thomas DD, Kamdar F. Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation. Frontiers in Cell and Developmental Biology. 10: 986107. PMID 36742199 DOI: 10.3389/fcell.2022.986107  0.771
2023 Rustad MD, Roopnarine O, Cornea RL, Thomas DD. Interaction of DWORF with SERCA and PLB as determined by EPR spectroscopy. Biochemical and Biophysical Research Communications. 645: 97-102. PMID 36682333 DOI: 10.1016/j.bbrc.2023.01.041  0.782
2023 Thomas DD, Roopnarine O. An Overview of the Actin-Myosin Interaction. Results and Problems in Cell Differentiation. 36: 1-5. PMID 23132619 DOI: 10.1007/978-3-540-46558-4_1  0.713
2022 Bidwell PA, Yuen SL, Li J, Berg K, Rebbeck RT, Aldrich CC, Roopnarine O, Cornea RL, Thomas DD. A Large-Scale High-Throughput Screen for Modulators of SERCA Activity. Biomolecules. 12. PMID 36551215 DOI: 10.3390/biom12121789  0.799
2022 Rebbeck R, Ginsburg KS, Ko CY, Fasoli A, Rusch K, Cai GF, Dong X, Thomas DD, Bers DM, Cornea RL. Synergistic FRET assays for drug discovery targeting RyR2 channels. Journal of Molecular and Cellular Cardiology. 168: 13-23. PMID 35405106 DOI: 10.1016/j.yjmcc.2022.04.002  0.612
2021 Roopnarine O, Thomas DD. Mechanistic analysis of actin-binding compounds that affect the kinetics of cardiac myosin-actin interaction. The Journal of Biological Chemistry. 100471. PMID 33639160 DOI: 10.1016/j.jbc.2021.100471  0.756
2021 Li A, Yuen SL, Stroik DR, Kleinboehl E, Cornea RL, Thomas DD. The transmembrane peptide DWORF activates SERCA2a via dual mechanisms. The Journal of Biological Chemistry. 100412. PMID 33581112 DOI: 10.1016/j.jbc.2021.100412  0.814
2020 Nikolaienko R, Bovo E, Rebbeck RT, Kahn D, Thomas DD, Cornea RL, Zima AV. The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor. Redox Biology. 37: 101729. PMID 32980662 DOI: 10.1016/J.Redox.2020.101729  0.342
2020 Autry JM, Karim CB, Cocco M, Carlson SF, Thomas DD, Valberg SJ. Purification of sarcoplasmic reticulum vesicles from horse gluteal muscle. Analytical Biochemistry. 113965. PMID 32956693 DOI: 10.1016/J.Ab.2020.113965  0.374
2020 Vetter A, Martin AA, Thompson BR, Thomas DD, Metzger JM. Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle. Journal of Molecular and Cellular Cardiology. PMID 32791214 DOI: 10.1016/J.Yjmcc.2020.07.012  0.387
2020 Guhathakurta P, Phung LA, Prochniewicz E, Lichtenberger S, Wilson A, Thomas DD. Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle. The Journal of Biological Chemistry. PMID 32788211 DOI: 10.1074/Jbc.Ra120.014445  0.388
2020 Schaaf TM, Kleinboehl E, Yuen SL, Roelike LN, Svensson B, Thompson AR, Cornea RL, Thomas DD. Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules that Enhance Ca Transport. Cells. 9. PMID 32397211 DOI: 10.3390/Cells9051170  0.398
2020 McCarthy MR, Savich Y, Cornea RL, Thomas DD. Resolved Structural States of Calmodulin in Regulation of Skeletal Muscle Calcium Release. Biophysical Journal. PMID 32049056 DOI: 10.1016/J.Bpj.2020.01.010  0.45
2020 Rebbeck RT, Singh DP, Janicek KA, Bers DM, Thomas DD, Launikonis BS, Cornea RL. RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca assays. Scientific Reports. 10: 1791. PMID 32019969 DOI: 10.1038/S41598-020-58461-1  0.383
2020 Nikolaienko R, Bovo E, Yuen S, Autry JM, Robia SL, Cornea RL, Thomas DD, Zima AV. Development of a High-Throughput Assay using R-CEPIA1er Fluorescence to Assess Small-Molecule Modulators of SERCA Activity in Living Cells Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.847  0.593
2020 Chu S, Byrapuneni S, Thomas DD, Muretta JM. Observing the Myosin Super-Relaxed State (SRX) in Cardiac Thick Filaments Biophysical Journal. 118: 596a. DOI: 10.1016/J.Bpj.2019.11.3222  0.328
2020 Guhathakurta P, Phung L, Lichtenberger S, Prochniewicz E, Thomas DD. Actin-Binding Compounds, Discovered from Fret-Based High-Throughput Screening, Differentially Affect Skeletal and Cardiac Muscle Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3213  0.338
2020 Li A, Stroik D, Schaaf T, Yuen S, Kleinboehl E, Cornea RL, Thomas DD. Biophysics of the SERCA2A/DWORF Complex, Implications for Treatment of Heart Failure Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3210  0.756
2020 Roopnarine O, Thomas DD. Actin-Binding Compounds that Affect the ATP-induced Dissociation of the Actin-Myosin Complex Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1829  0.746
2020 Savich Y, McCarthy MR, Thomas DD. Relgulatory Light Chain Orientaiton on Myosin S1 Using a Bifunctional Spin Label Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1588  0.307
2019 Stroik DR, Ceholski DK, Bidwell PA, Mleczko J, Thanel PF, Kamdar F, Autry JM, Cornea RL, Thomas DD. Viral expression of a SERCA2a-activating PLB mutant improves calcium cycling and synchronicity in dilated cardiomyopathic hiPSC-CMs. Journal of Molecular and Cellular Cardiology. PMID 31751570 DOI: 10.1016/J.Yjmcc.2019.11.147  0.796
2019 Martin PD, Svensson B, Thomas DD, Stoll S. Trajectory-Based Simulation of EPR Spectra: Models of Rotational Motion for Spin Labels on Proteins. The Journal of Physical Chemistry. B. PMID 31693365 DOI: 10.1021/Acs.Jpcb.9B02693  0.352
2019 Lo CH, Schaaf TM, Grant BD, Lim CK, Bawaskar P, Aldrich CC, Thomas DD, Sachs JN. Noncompetitive inhibitors of TNFR1 probe conformational activation states. Science Signaling. 12. PMID 31363069 DOI: 10.1126/Scisignal.Aav5637  0.337
2019 Binder BP, Thompson AR, Thomas DD. Atomistic Models from Orientation and Distance Constraints Using EPR of a Bifunctional Spin Label. Biophysical Journal. PMID 31301803 DOI: 10.1016/J.Bpj.2019.04.042  0.434
2019 Savich Y, Binder BP, Thompson AR, Thomas DD. Myosin lever arm orientation in muscle determined with high angular resolution using bifunctional spin labels. The Journal of General Physiology. PMID 31227551 DOI: 10.1085/Jgp.201812210  0.392
2019 Stroik D, Yuen S, Kleinboehl E, Janicek K, Schaaf T, Cornea R, Thomas D. Live-Cell FRET Biosensors for High-Throughput Screening Targeting the SERCA2a/Plb Complex Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.711  0.761
2019 Roopnarine O, Thomas DD. Actin-Binding Compounds that Affect the Weak-To-Strong Actin-Myosin Interaction Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.665  0.742
2019 Svensson B, Rebbeck RT, Zhang J, Bers DM, Thomas DD, Cornea RL. FRET-Based Trilateration Resolves Distinct Structural States and Transitions of Calmodulin Bound to RyR Biophysical Journal. 116: 43a. DOI: 10.1016/J.Bpj.2018.11.274  0.327
2019 Savich Y, Lewis DG, Binder BP, Martin PD, Thomas DD. Myosin Orientation in a Muscle Fiber using Bifunctional Spin Labels with 4 Degrees Angular Resolution Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2195  0.332
2019 Tripathi A, Phung LA, Guhathakurta P, Thomas DD. Effects of Actin-Binding Compounds on the ATPase Activity of Myosin from Skeletal and Cardiac Muscle Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2092  0.363
2019 Rebbeck RT, Singh DP, Ginsburg KS, Dong X, Thomas DD, Bers DM, Launikonis BS, Cornea RL. High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development Biophysical Journal. 116: 380a. DOI: 10.1016/J.Bpj.2018.11.2062  0.564
2018 Lake EW, Muretta JM, Thompson AR, Rasmussen DM, Majumdar A, Faber EB, Ruff EF, Thomas DD, Levinson NM. Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states. Proceedings of the National Academy of Sciences of the United States of America. PMID 30518564 DOI: 10.1073/Pnas.1811158115  0.325
2018 Gunther LK, Rohde JA, Tang W, Walton SD, Unrath WC, Trivedi DV, Muretta JM, Thomas DD, Yengo CM. Converter domain mutations in myosin alter structural kinetics and motor function. The Journal of Biological Chemistry. PMID 30518549 DOI: 10.1074/Jbc.Ra118.006128  0.343
2018 Schaaf TM, Li A, Grant BD, Peterson K, Yuen S, Bawaskar P, Kleinboehl E, Li J, Thomas DD, Gillispie GD. Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening. Biosensors. 8. PMID 30352972 DOI: 10.3390/Bios8040099  0.343
2018 Phung LA, Karvinen SM, Colson BA, Thomas DD, Lowe DA. Age affects myosin relaxation states in skeletal muscle fibers of female but not male mice. Plos One. 13: e0199062. PMID 30226869 DOI: 10.1371/Journal.Pone.0199062  0.319
2018 Guhathakurta P, Prochniewicz E, Thomas DD. Actin-Myosin Interaction: Structure, Function and Drug Discovery. International Journal of Molecular Sciences. 19. PMID 30189615 DOI: 10.3390/Ijms19092628  0.444
2018 Stroik DR, Yuen SL, Janicek KA, Schaaf TM, Li J, Ceholski DK, Hajjar RJ, Cornea RL, Thomas DD. Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells. Scientific Reports. 8: 12560. PMID 30135432 DOI: 10.1038/S41598-018-29685-Z  0.81
2018 Rohde JA, Roopnarine O, Thomas DD, Muretta JM. Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin. Proceedings of the National Academy of Sciences of the United States of America. PMID 30018063 DOI: 10.1073/Pnas.1720342115  0.754
2018 Her C, Thompson AR, Karim CB, Thomas DD. Structural dynamics of calmodulin-ryanodine receptor interactions: electron paramagnetic resonance using stereospecific spin labels. Scientific Reports. 8: 10681. PMID 30013092 DOI: 10.1038/S41598-018-29064-8  0.452
2018 Fealey ME, Horn B, Coffman C, Miller R, Lin AY, Thompson AR, Schramel J, Groth E, Hinderliter A, Cembran A, Thomas DD. Dynamics of Dystrophin's Actin-Binding Domain. Biophysical Journal. PMID 30007583 DOI: 10.1016/J.Bpj.2018.05.039  0.804
2018 Martin PD, James ZM, Thomas DD. Effect of Phosphorylation on Interactions between Transmembrane Domains of SERCA and Phospholamban. Biophysical Journal. 114: 2573-2583. PMID 29874608 DOI: 10.1016/J.Bpj.2018.04.035  0.767
2018 Guhathakurta P, Prochniewicz E, Grant BD, Peterson KC, Thomas DD. High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin-myosin structure and function. The Journal of Biological Chemistry. PMID 29866882 DOI: 10.1074/Jbc.Ra118.002702  0.436
2018 Ceholski DK, Turnbull IC, Kong CW, Koplev S, Mayourian J, Gorski PA, Stillitano F, Skodras AA, Nonnenmacher M, Cohen N, Björkegren JLM, Stroik DR, Cornea RL, Thomas DD, Li RA, et al. Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 29752948 DOI: 10.1016/J.Yjmcc.2018.05.007  0.768
2018 Nelson SED, Ha KN, Gopinath T, Exline MH, Mascioni A, Thomas DD, Veglia G. Effects of the Arg9Cys and Arg25Cys mutations on phospholamban's conformational equilibrium in membrane bilayers. Biochimica Et Biophysica Acta. PMID 29501609 DOI: 10.1016/J.Bbamem.2018.02.030  0.379
2018 Ruff EF, Muretta JM, Thompson AR, Lake EW, Cyphers S, Albanese SK, Hanson SM, Behr JM, Thomas DD, Chodera JD, Levinson NM. A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation. Elife. 7. PMID 29465396 DOI: 10.7554/Elife.32766  0.327
2018 Fealey ME, Binder BP, Uversky VN, Hinderliter A, Thomas DD. Structural Impact of Phosphorylation and Dielectric Constant Variation on Synaptotagmin's IDR. Biophysical Journal. 114: 550-561. PMID 29414700 DOI: 10.1016/J.Bpj.2017.12.013  0.341
2018 Schaaf T, Li A, Grant B, Bawaskar P, Kleinboehl E, Li J, Gillispie G, Thomas D. Red-Shifted Fluorescent Proteins Improve FRET Biosensors for High-throughput Fluorescence Lifetime Screening Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.955  0.308
2018 Rustad MD, Martin PD, Stroik DR, Karim CB, Thomas DD. Protein-Protein Interactions of Co-reconstituted SERCA, PLB and DWORF Investigated by Electron Paramagnetic Resonance Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.893  0.777
2018 Her C, Thompson AR, Karim CB, Thomas DD. Probing the Calcium-Dependent Structural States of Calmodulin-RyR using Bifunctional Spin Labels and Deer Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.890  0.363
2018 Stroik DR, Yuen SL, Janicek KA, Schaaf TM, Cornea RL, Thomas DD. Discovery of SERCA2a/PLB Activators and Inhibitors by Structure-Based High-throughput Screening using Live Cell FRET Biosensors Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.827  0.774
2018 Chu S, Phung LA, Muretta JM, Thomas DD. Time-Resolved FRET Detection of the Myosin Super-Relaxed off State in Cardiac Thick Filament Biophysical Journal. 114: 502a. DOI: 10.1016/J.Bpj.2017.11.2746  0.331
2018 Li A, Stroik DR, Schaaf TM, Grant BD, Thomas DD. Biophysics of SERCA2a/DWORF Complex and Implications for Therapeutic Design Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2741  0.748
2018 Guhathakurta P, Prochniewicz E, Peterson KC, Grant BD, Gillispie GD, Thomas DD. High-Throughput Screening for Actin-Binding Compounds that Affect Actomyosin Structure and Function using Time-Resolved FRET Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.254  0.334
2017 O'Rourke AR, Lindsay A, Tarpey MD, Yuen S, McCourt P, Nelson DM, Perrin BJ, Thomas DD, Spangenburg EE, Lowe DA, Ervasti JM. Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms. The Febs Journal. PMID 29265728 DOI: 10.1111/Febs.14367  0.333
2017 Avery AW, Fealey ME, Wang F, Orlova A, Thompson AR, Thomas DD, Hays TS, Egelman EH. Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation. Nature Communications. 8: 1350. PMID 29116080 DOI: 10.1016/J.Bpj.2017.11.818  0.364
2017 Avery AW, Thomas DD, Hays TS. β-III-spectrin spinocerebellar ataxia type 5 mutation reveals a dominant cytoskeletal mechanism that underlies dendritic arborization. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078305 DOI: 10.1073/Pnas.1707108114  0.303
2017 Elam WA, Cao W, Kang H, Huehn A, Hocky GM, Prochniewicz E, Schramm AC, Negrón K, Garcia J, Bonello TT, Gunning PW, Thomas DD, Voth GA, Sindelar CV, De La Cruz EM. Phosphomimetic S3D-Cofilin Binds But Only Weakly Severs Actin Filaments. The Journal of Biological Chemistry. PMID 28939776 DOI: 10.1074/Jbc.M117.808378  0.369
2017 Guhathakurta P, Prochniewicz E, Roopnarine O, Rohde JA, Thomas DD. A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure. Biophysical Journal. 113: 91-100. PMID 28700929 DOI: 10.1016/J.Bpj.2017.05.027  0.769
2017 Rohde JA, Thomas DD, Muretta JM. Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223517 DOI: 10.1073/Pnas.1611698114  0.38
2017 Fealey ME, Thomas DD, Hinderliter A. Enhanced synaptotagmin plasticity derived from pairing intrinsic disorder with synaptic vesicle lipids. Communicative & Integrative Biology. 10: 0. DOI: 10.1080/19420889.2017.1343772  0.353
2017 Rohde JA, Cho H, Phung L, Thomas DD, Muretta JM. Cardiac Myosin Strutural Kinetics Modulated by Small Molecules Biophysical Journal. 112: 119a. DOI: 10.1016/J.Bpj.2016.11.670  0.37
2017 Stroik D, Li A, Schaaf T, Gruber S, Cornea R, Hajjar R, Thomas D. Targeting the Serca-Plb Complex using FRET in Living Cells Biophysical Journal. 112: 570a. DOI: 10.1016/J.Bpj.2016.11.3071  0.762
2017 Fealey ME, Avery AW, Hays TS, Thomas DD. Spectroscopic Probes of Actin and Actin-Binding Domains of Dystrophin and β-III-Spectrin Reveals Disease-Related Changes in Structural Dynamics Biophysical Journal. 112: 562a. DOI: 10.1016/J.Bpj.2016.11.3029  0.368
2017 Muretta J, Reddy BJ, Scarabelli G, Thomas DD, Grant B, Gross S, Rosenfeld S. An Allosteric Gear Shift Mechanism in Eg5 Enhances Mechanochemical Coupling and Shifts the Force-Velocity Landscape Biophysical Journal. 112: 44a. DOI: 10.1016/J.Bpj.2016.11.279  0.383
2017 Rebbeck RT, Ryan MV, Gillispie GD, Thomas DD, Bers DM, Cornea RL. High-Throughput Screens to Discover Inhibitors of Leaky Ryanodine Receptor Calcium Channels Biophysical Journal. 112: 483a. DOI: 10.1016/J.Bpj.2016.11.2616  0.388
2017 Savich Y, Binder BP, Martin PD, Thompson AR, Thomas DD. High-Resolution Structural Dynamics of Bifunctionally Spin-Labeled Myosin by EPR of Oriented Muscle Fibers Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2394  0.452
2017 Her C, McCaffrey JE, Karim CB, Thomas DD. EPR Structural Dynamics of Calmodulin-RyR Peptide Complex Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2393  0.429
2017 Martin P, Stoll S, Thomas D. Simulating Electron Paramagnetic Resonance Spectra of Slow-Motion Systems in the Time Domain Biophysical Journal. 112: 445a-446a. DOI: 10.1016/J.Bpj.2016.11.2388  0.34
2017 Phung LA, Muretta JM, Petersen KJ, Rohde JA, Mader TL, Lowe DA, Thomas DD. Probing Estradiol Effects on Super-Relaxed Myosin in Muscle Fibers with Fluorescence Biophysical Journal. 112: 237a. DOI: 10.1016/J.Bpj.2016.11.1299  0.409
2017 Guhathakurta P, Prochniewicz E, Peterson KC, Grant BD, Gillispie GD, Thomas DD. Detection of Small-Molecule Modulators of Actin-Myosin Structure and Function using High-Throughput Time-Resolved FRET Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1297  0.425
2017 Autry JM, Espinoza-Fonseca M, Svensson B, Karim CB, Valberg SJ, Lee JK, Thomas DD. The Energy-Transduction Domain of the SERCA Calcium Pump is a Prime Therapeutic Target in Heart Failure and Obesity Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.129  0.426
2017 Rebbeck RT, Svensson B, Haskin CE, Samso M, Bers DM, Thomas DD, Cornea RL. FRET Based Mapping of Calmodulin within the Ryanodine Receptor Biophysical Journal. 112: 231a. DOI: 10.1016/J.Bpj.2015.11.1465  0.434
2016 Her C, McCaffrey JE, Thomas DD, Karim CB. Calcium-Dependent Structural Dynamics of a Spin-Labeled RyR Peptide Bound to Calmodulin. Biophysical Journal. 111: 2387-2394. PMID 27926840 DOI: 10.1016/J.Bpj.2016.10.025  0.416
2016 Schaaf TM, Peterson KC, Grant BD, Bawaskar P, Yuen S, Li J, Muretta JM, Gillispie GD, Thomas DD. High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA. Journal of Biomolecular Screening. PMID 27899691 DOI: 10.1177/1087057116680151  0.375
2016 Schaaf TM, Peterson KC, Grant BD, Thomas DD, Gillispie GD. Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells. Journal of Biomolecular Screening. PMID 27879398 DOI: 10.1177/1087057116679637  0.323
2016 Bian T, Autry JM, Casemore D, Li J, Thomas DD, He G, Xing C. Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles. Biochemical and Biophysical Research Communications. PMID 27815070 DOI: 10.1016/J.Bbrc.2016.10.096  0.357
2016 Rebbeck RT, Essawy MM, Nitu FR, Grant BD, Gillispie GD, Thomas DD, Bers DM, Cornea RL. High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels. Journal of Biomolecular Screening. PMID 27760856 DOI: 10.1177/1087057116674312  0.382
2016 Autry JM, Thomas DD, Espinoza-Fonseca LM. Sarcolipin promotes uncoupling of the SERCA Ca(2+) pump by inducing a structural rearrangement in the energy-transduction domain. Biochemistry. PMID 27731980 DOI: 10.1021/Acs.Biochem.6B00728  0.39
2016 Swanson CJ, Sommese RF, Petersen KJ, Ritt M, Karslake J, Thomas DD, Sivaramakrishnan S. Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro. Plos One. 11: e0162331. PMID 27706148 DOI: 10.1371/Journal.Pone.0162331  0.363
2016 Lewis AK, Dunleavy KM, Senkow TL, Her C, Horn BT, Jersett MA, Mahling R, McCarthy MR, Perell GT, Valley CC, Karim CB, Gao J, Pomerantz WC, Thomas DD, Cembran A, et al. Oxidation increases the strength of the methionine-aromatic interaction. Nature Chemical Biology. PMID 27547920 DOI: 10.1038/Nchembio.2159  0.349
2016 Rebbeck RT, Nitu FR, Rohde D, Most P, Bers DM, Thomas DD, Cornea RL. S100A1 does not compete with calmodulin for ryanodine receptor binding but structurally alters the ryanodine receptor/calmodulin complex. The Journal of Biological Chemistry. PMID 27226555 DOI: 10.1074/Jbc.M115.713107  0.446
2016 Colson BA, Thompson AR, Espinoza-Fonseca LM, Thomas DD. Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics. Proceedings of the National Academy of Sciences of the United States of America. PMID 26908877 DOI: 10.1073/Pnas.1521281113  0.399
2016 Avery AW, Crain J, Thomas DD, Hays TS. A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding. Scientific Reports. 6: 21375. PMID 26883385 DOI: 10.1038/Srep21375  0.328
2016 Svensson B, Autry JM, Thomas DD. Molecular Modeling of Fluorescent SERCA Biosensors. Methods in Molecular Biology (Clifton, N.J.). 1377: 503-22. PMID 26695057 DOI: 10.1007/978-1-4939-3179-8_42  0.376
2016 Binder BP, Thompson AR, Cornea S, Thomas DD. Structural Transitions in Myosin I Detected by Conventional and Pulsed EPR of a Bifunctional Spin Label Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.857  0.444
2016 Soboleva T, Binder BP, Thompson AR, Thomas DD, Moen RJ. Detecting Structural Changes in Myosin using Bifunctional Spin Labels Biophysical Journal. 110: 152a. DOI: 10.1016/J.Bpj.2015.11.856  0.806
2016 Her C, Karim CB, Thomas DD. Structural Dynamics of Calmodulin using Bifunctional Spin Labels and Double Electron-Electron Resonance Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.855  0.442
2016 Martin P, James Z, McCaffrey J, Thomas D. Probing the Structural Mechanism of Cardiac Calcium Pump Regulation by Phospholamban with Site-Directed Spin Labeling Biophysical Journal. 110: 152. DOI: 10.1016/J.Bpj.2015.11.853  0.458
2016 McCaffrey JE, James ZM, Karim CB, Svensson B, Martin PD, Thomas DD. Structural Topology of SERCA-PLB Complex in Oriented Lipid Bicelles Detected by Multifrequency EPR Biophysical Journal. 110: 151a. DOI: 10.1016/J.Bpj.2015.11.851  0.757
2016 Fealey ME, Horn B, Cembran A, Hinderliter A, Thomas DD. Spectroscopic and Computational Analysis of Dystrophin Regulation of Actin Dynamics Biophysical Journal. 110: 1-8. DOI: 10.1016/J.Bpj.2015.11.735  0.441
2016 Autry JM, Espinoza-Fonseca M, Peterson KC, Svensson B, Thomas DD. Nanosecond Fluorescence and Microsecond Simulation of SERCA Regulatory Interactions with Sarcolipin and Phospholamban Biophysical Journal. 110: 629. DOI: 10.1016/J.Bpj.2015.11.3372  0.415
2016 Muretta J, Rohde J, Thomas DD. Structural Coordination of the Myosin Powerstroke Biophysical Journal. 110: 614a. DOI: 10.1016/J.Bpj.2015.11.3293  0.402
2016 Lee JK, Autry JM, Cornea R, Bleeker N, Casemore D, Xing C, Thomas DD. Crystal Structure of the Calcium ATPase SERCA in Complex to a Novel Anti-Cancer Agent that Targets Multidrug-Resistant Leukemia Biophysical Journal. 110: 39a. DOI: 10.1016/J.Bpj.2015.11.276  0.358
2016 Stroik D, Schaaf T, Gruber S, Bawaskar P, Gillispie GD, Hajjar R, Thomas DD. Targeting the SERCA-PLB Complex for Treatment of Heart Failure Biophysical Journal. 110: 509a. DOI: 10.1016/J.Bpj.2015.11.2719  0.821
2016 Svensson B, Rebbeck RT, Thomas DD, Cornea RL. Improved FRET-Based Trilateration Methods Applied to the Mapping of Calmodulin within the Ryanodine Receptor Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2626  0.36
2016 Schaaf TM, Li J, Yuen SL, Bawaskar P, Grant BD, Peterson KC, Thomas DD, Gillispie GG. SUPR: Spectral Unmixinig Plate Reader for Live-Cell FRET Biosensor Drug Screening Biophysical Journal. 110: 373. DOI: 10.1016/J.Bpj.2015.11.2011  0.314
2016 Guhathakurta P, Prochniewicz E, Thomas DD. Cardiomyopathy Mutation in Ventricular Essential Light Chain of Cardiac Myosin Alters Structural and Functional Interaction with Actin Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1601  0.412
2016 Rohde JA, Thomas DD, Muretta JM. Structural and Biochemical Kinetics of Cardiac Myosin and its Perturbation by a Known Heart Failure Drug Investigated with Transient Time-Resolved FRET Biophysical Journal. 110: 296a. DOI: 10.1016/J.Bpj.2015.11.1598  0.399
2016 Colson BA, Espinoza-Fonseca LM, Thomas DD. Structural Measurements within the M-Domain Reveal Unique Details of Cardiac Myosin Binding Protein-C Phosphorylation Biophysical Journal. 110: 2-3. DOI: 10.1016/J.Bpj.2015.11.1584  0.387
2016 Colson BA, Gallegos A, Lin B, Sadayappan S, Thomas DD. The N-Terminal Domains of MyBPC3 Restrict Actin Dynamics and Increase Resilience in a Phosphorylation-Dependent Manner Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1582  0.319
2016 McCarthy MR, Rebbeck RT, Cornea RL, Thomas DD. Structural Dynamics of Calmodulin in Regulation of Calcium Release in Health and Disease Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2015.11.1463  0.419
2015 Ablorh ND, Thomas DD. Phospholamban phosphorylation, mutation, and structural dynamics: a biophysical approach to understanding and treating cardiomyopathy. Biophysical Reviews. 7: 63-76. PMID 28509982 DOI: 10.1007/S12551-014-0157-Z  0.331
2015 McCaffrey JE, James ZM, Svensson B, Binder BP, Thomas DD. A bifunctional spin label reports the structural topology of phospholamban in magnetically-aligned bicelles. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 262: 50-56. PMID 26720587 DOI: 10.1016/J.Jmr.2015.12.005  0.746
2015 Muretta JM, Jun Y, Gross SP, Major J, Thomas DD, Rosenfeld SS. The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5. Proceedings of the National Academy of Sciences of the United States of America. 112: E6606-13. PMID 26627252 DOI: 10.1073/Pnas.1512305112  0.319
2015 Muretta JM, Rohde JA, Johnsrud DO, Cornea S, Thomas DD. Direct real-time detection of the structural and biochemical events in the myosin power stroke. Proceedings of the National Academy of Sciences of the United States of America. 112: 14272-7. PMID 26578772 DOI: 10.1073/Pnas.1514859112  0.372
2015 Karim CB, Michel Espinoza-Fonseca L, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A. Erratum: Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation. Scientific Reports. 5: 15872. PMID 26513659 DOI: 10.1038/Srep15872  0.72
2015 Thompson AR, Binder BP, McCaffrey JE, Svensson B, Thomas DD. Bifunctional Spin Labeling of Muscle Proteins: Accurate Rotational Dynamics, Orientation, and Distance by EPR. Methods in Enzymology. 564: 101-23. PMID 26477249 DOI: 10.1016/Bs.Mie.2015.06.029  0.422
2015 Karim CB, Michel Espinoza-Fonseca L, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A. Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation. Scientific Reports. 5: 14557. PMID 26411306 DOI: 10.1038/Srep14557  0.757
2015 Oda T, Yang Y, Uchinoumi H, Thomas DD, Chen-Izu Y, Kato T, Yamamoto T, Yano M, Cornea RL, Bers DM. Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity. Journal of Molecular and Cellular Cardiology. PMID 26092277 DOI: 10.1016/J.Yjmcc.2015.06.009  0.397
2015 Binder BP, Cornea S, Thompson AR, Moen RJ, Thomas DD. High-resolution helix orientation in actin-bound myosin determined with a bifunctional spin label. Proceedings of the National Academy of Sciences of the United States of America. 112: 7972-7. PMID 26056276 DOI: 10.1073/Pnas.1500625112  0.803
2015 Alamo L, Li XE, Espinoza-Fonseca LM, Pinto A, Thomas DD, Lehman W, Padrón R. Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back. Molecular Biosystems. 11: 2180-9. PMID 26038302 DOI: 10.1039/C5Mb00163C  0.38
2015 Espinoza-Fonseca LM, Alamo L, Pinto A, Thomas DD, Padrón R. Sequential myosin phosphorylation activates tarantula thick filament via a disorder-order transition. Molecular Biosystems. 11: 2167-79. PMID 26038232 DOI: 10.1039/C5Mb00162E  0.404
2015 Espinoza-Fonseca LM, Autry JM, Thomas DD. Sarcolipin and phospholamban inhibit the calcium pump by populating a similar metal ion-free intermediate state. Biochemical and Biophysical Research Communications. 463: 37-41. PMID 25983321 DOI: 10.1016/J.Bbrc.2015.05.012  0.396
2015 Iram SH, Gruber SJ, Raguimova ON, Thomas DD, Robia SL. ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening. Molecular Pharmacology. 88: 84-94. PMID 25924616 DOI: 10.1124/Mol.114.096792  0.811
2015 Espinoza-Fonseca LM, Autry JM, Ramírez-Salinas GL, Thomas DD. Atomic-level mechanisms for phospholamban regulation of the calcium pump. Biophysical Journal. 108: 1697-708. PMID 25863061 DOI: 10.1016/J.Bpj.2015.03.004  0.389
2015 Guhathakurta P, Prochniewicz E, Thomas DD. Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain. Proceedings of the National Academy of Sciences of the United States of America. 112: 4660-5. PMID 25825773 DOI: 10.1073/Pnas.1420101112  0.354
2015 McCaffrey JE, James ZM, Thomas DD. Optimization of bicelle lipid composition and temperature for EPR spectroscopy of aligned membranes. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 250: 71-5. PMID 25514061 DOI: 10.1016/J.Jmr.2014.09.026  0.71
2015 McCarthy MR, Thompson AR, Nitu F, Moen RJ, Olenek MJ, Klein JC, Thomas DD. Impact of methionine oxidation on calmodulin structural dynamics. Biochemical and Biophysical Research Communications. 456: 567-72. PMID 25478640 DOI: 10.1016/J.Bbrc.2014.11.091  0.825
2015 Colson BA, Petersen KJ, Collins BC, Lowe DA, Thomas DD. The myosin super-relaxed state is disrupted by estradiol deficiency. Biochemical and Biophysical Research Communications. 456: 151-5. PMID 25446114 DOI: 10.1016/J.Bbrc.2014.11.050  0.328
2015 Li J, Schaaf TM, Gruber SJ, Cornea RL, Autry JM, Yuen SL, Chen R, Peterson KC, Gillispie GD, Thomas DD. Using a Live-Cell High-Throughput Time-Resolved FRET Assay to Discover Enzyme Modulators Biophysical Journal. 108: 147a. DOI: 10.1016/J.Bpj.2014.11.810  0.75
2015 Muretta JM, Major J, Thomas DD, Steven RS. Structural-Kinetics of the Switch-1 Loop and Neck-Linker Elements Explains the Distinct Molecular Physiologies of Kinesin-1 and Kinesin-5 Biophysical Journal. 108: 138a. DOI: 10.1016/J.Bpj.2014.11.763  0.373
2015 Espinoza-Fonseca LM, Autry JM, Ramírez-Salinas GL, Thomas DD. Atomic-Level Characterization of the Inhibition Mechanism of the Calcium Pump by Phospholamban Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.731  0.374
2015 Svensson B, Dong X, Petersen KJ, James ZM, McCaffrey JE, Young HS, Thomas DD. Using Molecular Dynamics Simulations to Interpret Fluorescence and EPR Data on Labeled SERCA and Phospholamban Biophysical Journal. 108: 131a. DOI: 10.1016/J.Bpj.2014.11.729  0.809
2015 Nelson SE, Gopinath T, Thomas DD, Veglia G. Characterization of Calmodulin Binding to the Ryanodine Receptor by Solution and Solid-State NMR Biophysical Journal. 108: 616a. DOI: 10.1016/J.Bpj.2014.11.3354  0.43
2015 Guhathakurta P, Prochniewicz E, Thomas DD. Effect of Actin and Nucleotide on the Movement of A1-Type Myosin Essential Light Chain, Detected by Time-Resolved FRET Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.3235  0.325
2015 Binder BP, Thompson AR, Cornea S, Moen RJ, Thomas DD. Backbone Orientation and Distance Measurements in Myosin II: Applications of High-Resolution EPR using a Bifunctional Spin Label Biophysical Journal. 108: 592a. DOI: 10.1016/J.Bpj.2014.11.3225  0.798
2015 Fealey ME, Thomas DD. Probing Conformational Change in the First Actin-Binding Domain of Dystrophin Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2812  0.455
2015 Rohde J, Johnsrud DO, Cornea S, Peterson KC, Gillispie GD, Thomas DD, Muretta JM. Structural Thermodynamics and Kinetics of the Cardiac Myosin/Omecamtiv Mecarbil Complex Revealed by Time-Resolved FRET Biophysical Journal. 108: 445a. DOI: 10.1016/J.Bpj.2014.11.2429  0.408
2015 Rubin JE, Svensson B, Peterson KC, Robia SL, Thomas DD, Autry JM. Hierarchy of Regulatory Interactions in the Sarcoplasmic Reticulum Calcium Transport Complex Biophysical Journal. 108: 423a. DOI: 10.1016/J.Bpj.2014.11.2313  0.662
2015 Gruber SJ, Goldblum R, Zhong J, Peterson K, Schaaf TM, Autry JM, Gillispie GD, Thomas DD, Muretta JM. Direct Detection of the Thermodynamics and Structural Kinetics of a 2-Color SERCA Biosensor by Transient Time-Resolved FRET Biophysical Journal. 108: 362a. DOI: 10.1016/J.Bpj.2014.11.1985  0.776
2015 Schaaf T, Li J, Foncea R, Gruber S, Peterson K, Petersen K, Razvan C, Gillispie G, Bernlohr D, Thomas D. A Two-Color Non-Muscle SERCA FRET Sensor for Diabetes Drug Discovery Using Fluorescence Lifetime Detection Biophysical Journal. 108: 346a. DOI: 10.1016/J.Bpj.2014.11.1894  0.745
2015 Colson BA, Petersen KJ, Collins BC, Thomas DD, Lowe DA. The Myosin Super-Relaxed State is Regulated by Estradiol Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1850  0.342
2015 Matzke JG, Thomas DD, Petersen KJ, Muretta JM, Titus MA. A Myosin II FRET-Based Biosensor Expressed in Dictyostelium Biophysical Journal. 108: 301a. DOI: 10.1016/J.Bpj.2014.11.1638  0.431
2015 Elam WA, Kang H, Prochniewicz E, Nieves-Torres K, Thomas DD, De La Cruz EM. Phosphomimic S3D Cofilin Binds Actin Filaments but does not Sever them Biophysical Journal. 108: 300a. DOI: 10.1016/J.Bpj.2014.11.1630  0.355
2015 Rebbeck RT, Nitu FR, Rohde D, Most P, Bers DM, Thomas DD, Cornea RL. FRET-Based RyR-Selective Detection Reveals No Significant Competition between CaM and S100A1 Binding to RyRs Biophysical Journal. 108: 264a. DOI: 10.1016/J.Bpj.2014.11.1458  0.42
2015 Her C, Karim CB, Thomas DD. EPR with Rigidly Bound Spin Labels used to Probe the Interaction of Calmodulin with the Ryanodine Receptor Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1187  0.419
2015 Senkow TL, Lewis AK, McCarthy MR, Her C, Thomas DD, Sachs JN. Methionine-Aromatic Interactions in Calmodulin: A Replica Exchange MD and EPR Spectroscopy Study Biophysical Journal. 108: 213a-214a. DOI: 10.1016/J.Bpj.2014.11.1180  0.342
2014 Svensson B, Oda T, Nitu FR, Yang Y, Cornea I, Chen-Izu Y, Fessenden JD, Bers DM, Thomas DD, Cornea RL. FRET-based trilateration of probes bound within functional ryanodine receptors. Biophysical Journal. 107: 2037-48. PMID 25418089 DOI: 10.1016/J.Bpj.2014.09.029  0.445
2014 Moen RJ, Cornea S, Oseid DE, Binder BP, Klein JC, Thomas DD. Redox-sensitive residue in the actin-binding interface of myosin. Biochemical and Biophysical Research Communications. 453: 345-9. PMID 25264102 DOI: 10.1016/J.Bbrc.2014.09.072  0.81
2014 Ablorh NA, Dong X, James ZM, Xiong Q, Zhang J, Thomas DD, Karim CB. Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscle. The Journal of Biological Chemistry. 289: 29397-405. PMID 25190804 DOI: 10.1074/Jbc.M114.556621  0.796
2014 Mahalingam M, Girgenrath T, Svensson B, Thomas DD, Cornea RL, Fessenden JD. Structural mapping of divergent regions in the type 1 ryanodine receptor using fluorescence resonance energy transfer. Structure (London, England : 1993). 22: 1322-32. PMID 25132084 DOI: 10.1016/J.Str.2014.07.003  0.383
2014 Espinoza-Fonseca LM, Colson BA, Thomas DD. Effects of pseudophosphorylation mutants on the structural dynamics of smooth muscle myosin regulatory light chain. Molecular Biosystems. 10: 2693-8. PMID 25091814 DOI: 10.1039/C4Mb00364K  0.41
2014 Dong X, Thomas DD. Time-resolved FRET reveals the structural mechanism of SERCA-PLB regulation. Biochemical and Biophysical Research Communications. 449: 196-201. PMID 24813991 DOI: 10.1016/J.Bbrc.2014.04.166  0.687
2014 Espinoza-Fonseca LM, Autry JM, Thomas DD. Microsecond molecular dynamics simulations of Mg²⁺- and K⁺-bound E1 intermediate states of the calcium pump. Plos One. 9: e95979. PMID 24760008 DOI: 10.1371/Journal.Pone.0095979  0.375
2014 Lewis AK, James ZM, McCaffrey JE, Braun AR, Karim CB, Thomas DD, Sachs JN. Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation. Biophysical Journal. 106: L21-4. PMID 24655519 DOI: 10.1016/J.Bpj.2014.01.044  0.71
2014 Gruber SJ, Cornea RL, Li J, Peterson KC, Schaaf TM, Gillispie GD, Dahl R, Zsebo KM, Robia SL, Thomas DD. Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells. Journal of Biomolecular Screening. 19: 215-22. PMID 24436077 DOI: 10.1016/J.Bpj.2013.11.2409  0.801
2014 Moen RJ, Klein JC, Thomas DD. Electron paramagnetic resonance resolves effects of oxidative stress on muscle proteins. Exercise and Sport Sciences Reviews. 42: 30-6. PMID 24188980 DOI: 10.1249/Jes.0000000000000004  0.819
2014 Colson BA, James ZM, Klein JC, Thomas DD. Structural Dynamics of Cardiac Myosin Binding Protein-C and its Myofilament Binding Partners, Detected by Site-Directed Spectroscopy Biophysical Journal. 106: 162a. DOI: 10.1016/J.Bpj.2013.11.923  0.823
2014 Colson BA, Mauseth MA, Kast DJ, Espinoza-Fonseca LM, Roopnarine O, Thomas DD. Atomic-Level Visualization of Smooth Muscle Activation by Phosphorylation of the Myosin Regulatory Light Chain Biophysical Journal. 106: 161a-162a. DOI: 10.1016/J.Bpj.2013.11.922  0.811
2014 Svensson B, Oda T, Nitu FR, Cornea I, Bers DM, Thomas DD, Cornea RL. FRET-Based Trilateration of a Domain Peptide Bound within Functional Ryanodine Receptors in Cardiomyocytes Biophysical Journal. 106: 107a. DOI: 10.1016/J.Bpj.2013.11.658  0.361
2014 Muretta J, Parks WB, Petersen K, Goulet A, Moores C, Thomas DD, Rosenfeld S. Structural Kinetics of the Mitotic Kinesin Eg5 Biophysical Journal. 106: 779a. DOI: 10.1016/J.Bpj.2013.11.4269  0.394
2014 Autry JM, Schaid MD, Peterson KC, Thomas DD. Protein-Protein Interactions in Skeletal Muscle Calcium Transport Regulation Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.4004  0.372
2014 Olenek M, Thomas DD, Klein JC. Computational Simulations Reveal How Calmodulin Methionine Oxidation Triggers Large-Scale Changes in Structural Dynamics Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3595  0.698
2014 Fealey ME, Crain J, Hinderliter A, Thomas DD. Probing Allosteric Mechanisms of Utrophin and Dystrophin Actin-Binding Domains, using Thermal Denaturation Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3591  0.417
2014 Dong X, Thomas DD. Regulatory Mechanism of SERCA-PLB Complex Determined by FRET Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3245  0.688
2014 James ZM, McCaffrey JE, Torgersen KD, Karim CB, Thomas DD. Phosphorylation Alters the Transmembrane Binding Interface Between Phospholamban and SERCA Biophysical Journal. 106: 585a-586a. DOI: 10.1016/J.Bpj.2013.11.3244  0.833
2014 Ablorh ND, Dong X, James ZM, Langer HR, Thomas DD, Karim CB. Distinct Functional Effects of Phospholamban Phosphorylation States Biophysical Journal. 106: 585a. DOI: 10.1016/J.Bpj.2013.11.3243  0.796
2014 McCaffrey JE, James ZM, Karim CB, Thomas DD. Multifrequency EPR Detects Orientation of Calcium Transport Proteins in Lipid Bicelles Biophysical Journal. 106: 584a. DOI: 10.1016/J.Bpj.2013.11.3237  0.76
2014 Espinoza-Fonseca LM, Thomas DD. Protonation-Dependent Structural Transitions of the Calcium Pump Studied by Microsecond Molecular Dynamics Simulations Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3235  0.398
2014 Langer HR, Autry JM, Carlson B, Gadek M, Thomas DD. Clinical Trials of Gene Therapy for Heart Failure: Quantitation of the Cardiac Calcium Pump by Immunochemistry Biophysical Journal. 106: 5-7. DOI: 10.1016/J.Bpj.2013.11.3144  0.315
2014 Muretta JM, Prochniewicz E, Thomas DD. Biophysical Analysis of the Putative Heart Failure Drug Omecamtiv Mecarbil Biophysical Journal. 106: 562a-563a. DOI: 10.1016/J.Bpj.2013.11.3124  0.383
2014 Nelson SE, Nitu F, Cornea R, Thomas DD, Veglia G. Structure-Function Relationships of M124Q Calmodulin, a Mutant that Mimics Oxidative Insults Biophysical Journal. 106: 528a. DOI: 10.1016/J.Bpj.2013.11.2945  0.428
2014 Vetter AD, Thompson B, Muretta JM, Thomas DD, Metzger JM. Cardiac Troponin I A164H and pH-Dependent Inotropy Biophysical Journal. 106: 349a-350a. DOI: 10.1016/J.Bpj.2013.11.1989  0.345
2014 McCarthy M, Olenek M, Reuter M, Moen R, Thomas DD, Klein JC. Pulsed EPR Distance Measurements Resolve the Impact of Site-Specific Calmodulin Methionine Oxidation Biophysical Journal. 106: 251a. DOI: 10.1016/J.Bpj.2013.11.1480  0.813
2014 Petersen KJ, Muretta JM, Higgins SE, Peterson KC, Gillispie GD, Thomas DD. High throughput Time Resolved Fluorescence in a Microplate Reader Biophysical Journal. 106: 205a-206a. DOI: 10.1016/J.Bpj.2013.11.1207  0.326
2014 Binder B, Thompson A, Mello R, Moen R, Thomas DD. High-Resolution Measurement of Distance and Orientation in Myosin: EPR of a Bifunctional Spin Label Biophysical Journal. 106: 192a. DOI: 10.1016/J.Bpj.2013.11.1137  0.827
2013 Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM. Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. Cell Reports. 5: 1725-36. PMID 24360963 DOI: 10.1016/J.Celrep.2013.11.040  0.426
2013 Greaser ML, Potter JD, Thomas DD, Strasburg GM, Lehrer SS, Wang CL, Grabarek Z. John Gergely (1919-2013): a pillar in the muscle protein field. Journal of Muscle Research and Cell Motility. 34: 441-6. PMID 24264290 DOI: 10.1007/S10974-013-9370-9  0.521
2013 Lewin J, Puri A, Quek R, Ngan R, Alcasabas AP, Wood D, Thomas D. Management of sarcoma in the Asia-Pacific region: resource-stratified guidelines. The Lancet. Oncology. 14: e562-70. PMID 24176574 DOI: 10.1016/S1470-2045(13)70475-3  0.311
2013 Muretta JM, Behnke-Parks WM, Major J, Petersen KJ, Goulet A, Moores CA, Thomas DD, Rosenfeld SS. Loop L5 assumes three distinct orientations during the ATPase cycle of the mitotic kinesin Eg5: a transient and time-resolved fluorescence study. The Journal of Biological Chemistry. 288: 34839-49. PMID 24145034 DOI: 10.1074/Jbc.M113.518845  0.389
2013 Pallikkuth S, Blackwell DJ, Hu Z, Hou Z, Zieman DT, Svensson B, Thomas DD, Robia SL. Phosphorylated phospholamban stabilizes a compact conformation of the cardiac calcium-ATPase. Biophysical Journal. 105: 1812-21. PMID 24138857 DOI: 10.1016/J.Bpj.2013.08.045  0.688
2013 Trivedi DV, Muretta JM, Swenson AM, Thomas DD, Yengo CM. Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle. Biochemistry. 52: 4710-22. PMID 23725637 DOI: 10.1021/Bi4004364  0.356
2013 Morgounova E, Shao Q, Hackel BJ, Thomas DD, Ashkenazi S. Photoacoustic lifetime contrast between methylene blue monomers and self-quenched dimers as a model for dual-labeled activatable probes. Journal of Biomedical Optics. 18: 56004. PMID 23640075 DOI: 10.1117/1.Jbo.18.5.056004  0.309
2013 Muretta JM, Petersen KJ, Thomas DD. Direct real-time detection of the actin-activated power stroke within the myosin catalytic domain. Proceedings of the National Academy of Sciences of the United States of America. 110: 7211-6. PMID 23589853 DOI: 10.1073/Pnas.1222257110  0.403
2013 Prochniewicz E, Guhathakurta P, Thomas DD. The structural dynamics of actin during active interaction with myosin depends on the isoform of the essential light chain. Biochemistry. 52: 1622-30. PMID 23339370 DOI: 10.1021/Bi3014467  0.425
2013 Moen RJ, Thomas DD, Klein JC. Conformationally trapping the actin-binding cleft of myosin with a bifunctional spin label. The Journal of Biological Chemistry. 288: 3016-24. PMID 23250750 DOI: 10.1074/Jbc.M112.428565  0.822
2013 Cornea RL, Gruber SJ, Lockamy EL, Muretta JM, Jin D, Chen J, Dahl R, Bartfai T, Zsebo KM, Gillispie GD, Thomas DD. High-throughput FRET assay yields allosteric SERCA activators. Journal of Biomolecular Screening. 18: 97-107. PMID 22923787 DOI: 10.1177/1087057112456878  0.804
2013 Vetter AD, Thompson BR, Muretta JM, Thomas DD, Metzger JM. Conformational Dynamics of a “Titratable” Cardiac Inotrope Biophysical Journal. 104: 154a. DOI: 10.1016/J.Bpj.2012.11.871  0.364
2013 Petersen KJ, Higgins SE, Peterson KC, Gillispie GD, Thomas DD. A Microplate-Based Instrument for Resolving Fluorescence Lifetimes Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3771  0.314
2013 Binder B, Mello R, Moen R, Thomas DD. High-Resolution EPR of a Bifunctional Spin Label Reveals Structural Transitions within Myosin's Catalytic Domain Biophysical Journal. 104: 648a. DOI: 10.1016/J.Bpj.2012.11.3581  0.829
2013 Crain J, Lin AY, One Feather B, Brate A, Matthews G, Svensson B, Thomas DD. Large Scale Opening of the N Terminal Actin-Binding Domain of Dystrophin Detected by Dipolar Electron-Electron Resonance (DEER) Biophysical Journal. 104: 648a. DOI: 10.1016/J.Bpj.2012.11.3578  0.804
2013 Brate A, Lin A, Crain J, Prochniewicz E, Ervasti J, Thomas DD. Effects of Disease Causing Point Mutations on Actin's Resilience Biophysical Journal. 104: 648a. DOI: 10.1016/J.Bpj.2012.11.3577  0.784
2013 Swenson AM, Muretta JM, D' Amico F, Unrath WC, Thomas DD, Yengo CM. Magnesium-Dependence and Active Site Dynamics in Myosin V and Myosin II Biophysical Journal. 104: 642a-643a. DOI: 10.1016/J.Bpj.2012.11.3550  0.397
2013 Klein JC, Moen RJ, Ryan AH, Thomas DD. Structural Impact of Site-Specific Calmodulin Methionine Oxidation Biophysical Journal. 104: 453a. DOI: 10.1016/J.Bpj.2012.11.2506  0.8
2013 Nitu FR, Fruen BR, Rohde D, Most P, Bers DM, Thomas DD, Cornea RL. FRET Detection of CaM-RyR2 Binding Modulation by S100A1 Biophysical Journal. 104: 446a. DOI: 10.1016/J.Bpj.2012.11.2474  0.395
2013 Gillispie GD, Peterson KC, Li J, Thomas DD. Fluorescence Lifetime Microplate Reader for Structural Biology: High Performance and High-Throughput in the Same Tool Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1919  0.308
2013 Guhathakurta P, Prochniewicz E, Thomas DD. Structural Transitions within the Actomyosin Complex in the Presence of Saturating ATP, Detected by Time-Resolved FRET Biophysical Journal. 104: 3-6. DOI: 10.1016/J.Bpj.2012.11.1705  0.421
2013 Muretta JM, Petersen KJ, Thomas DD. Coordination of Actin-Activated Phosphate Release and the Myosin Power-Stroke Detected by Transient Time-Resolved FRET Biophysical Journal. 104: 306a. DOI: 10.1016/J.Bpj.2012.11.1704  0.396
2013 Dong X, Li J, Karim CB, Thomas DD. Probing Cardiac Membrane Proteins with Fluorescence Resonance Energy Transfer Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1668  0.715
2013 McCaffrey JE, James ZM, Karim CB, Thomas DD. Orientation of Phospholamban in Lipid Bicelles Detected by Electron Paramagnetic Resonance Biophysical Journal. 104: 299a. DOI: 10.1016/J.Bpj.2012.11.1667  0.767
2013 James ZM, McCaffrey JE, Karim CB, Thomas DD. EPR Detects Changes in the Transmembrane Region of the SERCA-Phospholamban Complex upon Ser16 Phosphorylation Biophysical Journal. 104: 299a. DOI: 10.1016/J.Bpj.2012.11.1666  0.779
2013 Gruber SJ, Peterson KC, Svensson B, Robia SL, Thomas DD. In-Cell FRET as a Tool to Develop SERCA Activators for Drug or Gene Therapy Biophysical Journal. 104: 299a. DOI: 10.1016/J.Bpj.2012.11.1665  0.817
2013 Li J, Langer H, Peterson KC, Muretta JM, Gillispie GD, Cornea RL, Thomas DD. Screening for SERCA Activators using a High-throughput Time-Resolved FRET Assay Biophysical Journal. 104: 299a. DOI: 10.1016/J.Bpj.2012.11.1664  0.36
2013 Autry JM, Haydon S, Gruber SJ, Peterson KC, Svensson B, Thomas DD. Time Resolved FRET in the SR Ca-ATPase Biophysical Journal. 104: 298a-299a. DOI: 10.1016/J.Bpj.2012.11.1663  0.781
2013 Colson BA, James ZM, Thomas DD. Structural Dynamics of Actin-Myosin Bound and Unbound States of Cardiac Myosin Binding Protein-C Detected by Dipolar EPR Biophysical Journal. 104: 187a. DOI: 10.1016/J.Bpj.2012.11.1054  0.759
2012 Colson BA, Rybakova IN, Prochniewicz E, Moss RL, Thomas DD. Cardiac myosin binding protein-C restricts intrafilament torsional dynamics of actin in a phosphorylation-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 109: 20437-42. PMID 23169656 DOI: 10.1073/Pnas.1213027109  0.36
2012 James ZM, McCaffrey JE, Torgersen KD, Karim CB, Thomas DD. Protein-protein interactions in calcium transport regulation probed by saturation transfer electron paramagnetic resonance. Biophysical Journal. 103: 1370-8. PMID 22995510 DOI: 10.1016/J.Bpj.2012.08.032  0.828
2012 Autry JM, Rubin JE, Svensson B, Li J, Thomas DD. Nucleotide activation of the Ca-ATPase. The Journal of Biological Chemistry. 287: 39070-82. PMID 22977248 DOI: 10.1074/Jbc.M112.404434  0.455
2012 Colson BA, Gruber SJ, Thomas DD. Structural dynamics of muscle protein phosphorylation. Journal of Muscle Research and Cell Motility. 33: 419-29. PMID 22930331 DOI: 10.1007/S10974-012-9317-6  0.783
2012 Hou Z, Hu Z, Blackwell DJ, Miller TD, Thomas DD, Robia SL. 2-Color calcium pump reveals closure of the cytoplasmic headpiece with calcium binding. Plos One. 7: e40369. PMID 22808146 DOI: 10.1371/Journal.Pone.0040369  0.681
2012 Guhathakurta P, Prochniewicz E, Muretta JM, Titus MA, Thomas DD. Allosteric communication in Dictyostelium myosin II. Journal of Muscle Research and Cell Motility. 33: 305-12. PMID 22752265 DOI: 10.1007/S10974-012-9304-Y  0.411
2012 Lin AY, Prochniewicz E, Henderson DM, Li B, Ervasti JM, Thomas DD. Impacts of dystrophin and utrophin domains on actin structural dynamics: implications for therapeutic design. Journal of Molecular Biology. 420: 87-98. PMID 22504225 DOI: 10.1016/J.Jmb.2012.04.005  0.798
2012 Gruber SJ, Haydon S, Thomas DD. Phospholamban mutants compete with wild type for SERCA binding in living cells Biochemical and Biophysical Research Communications. 420: 236-240. PMID 22405774 DOI: 10.1016/J.Bbrc.2012.02.125  0.761
2012 Mello RN, Thomas DD. Three distinct actin-attached structural states of myosin in muscle fibers Biophysical Journal. 102: 1088-1096. PMID 22404931 DOI: 10.1016/J.Bpj.2011.11.4027  0.802
2012 Li J, James ZM, Dong X, Karim CB, Thomas DD. Structural and functional dynamics of an integral membrane protein complex modulated by lipid headgroup charge. Journal of Molecular Biology. 418: 379-89. PMID 22381409 DOI: 10.1016/J.Jmb.2012.02.011  0.801
2012 Ablorh NA, Miller T, Nitu F, Gruber SJ, Karim C, Thomas DD. Accurate quantitation of phospholamban phosphorylation by immunoblot. Analytical Biochemistry. 425: 68-75. PMID 22369895 DOI: 10.1016/J.Ab.2012.01.028  0.733
2012 Henderson DM, Lin AY, Thomas DD, Ervasti JM. The carboxy-terminal third of dystrophin enhances actin binding activity. Journal of Molecular Biology. 416: 414-24. PMID 22226838 DOI: 10.1016/J.Jmb.2011.12.040  0.804
2012 Moen RJ, Klein JC, Smith EA, Titus MA, Thomas DD. Functional and Structural Impact of Site-Directed Methionine Oxidation in Myosin Biophysical Journal. 102: 150a. DOI: 10.1016/J.Bpj.2011.11.817  0.807
2012 Li J, James Z, Karim CB, Dong D, Thomas DD. Physical and Functional Interaction of Membrane Proteins Modulated by Electrostatic Interactions with Membrane Surface Charge Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3851  0.35
2012 Gruber SJ, Haydon S, Thomas DD. Fluorescence and Functional Measurements of Phospholamban Mutant Competition Biophysical Journal. 102: 709a. DOI: 10.1016/J.Bpj.2011.11.3850  0.761
2012 Hou Z, Hu Z, Blackwell DJ, Miller TD, Thomas DD, Robia SL. Quantification of Calcium Pump Structure Changes in Live Celss Biophysical Journal. 102: 709a. DOI: 10.1016/J.Bpj.2011.11.3848  0.658
2012 Autry JM, Rubin JE, Svensson B, Li J, Thomas DD. Time-Resolved Fluorescence and Molecular Modeling of FITC-Labeled Ca-ATPase Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3847  0.436
2012 McCaffrey JE, James ZM, Torgersen KD, Karim CB, Howard EC, Thomas DD. Structural Dynamics of Calcium Transport Proteins Detected by Saturation Transfer Electron Paramagnetic Resonance Biophysical Journal. 102: 709a. DOI: 10.1016/J.Bpj.2011.11.3846  0.826
2012 Muretta JM, Petersen KJ, Titus M, Thomas DD. Actin Straightens the Myosin Relay Helix during the Powerstroke Biophysical Journal. 102: 567a. DOI: 10.1016/J.Bpj.2011.11.3087  0.427
2012 Abdella RH, Thorson DL, Moen RJ, Klein JC, Thomas DD. Site-Specific Methionine Oxidation and Calmodulin Molecular Dynamics Biophysical Journal. 102: 508a. DOI: 10.1016/J.Bpj.2011.11.2784  0.8
2012 Colson BA, Rybakova IN, Moss RL, Prochniewicz E, Thomas DD. Effects of Myosin Binding Protein-C Isoform, Phosphorylation, and Domains on the Rotational Dynamics of Actin Filaments Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2383  0.352
2012 Svensson B, Lockamy EL, Dong D, Young HS, Thomas DD. Simulations of Fluorescent Probes Attached to SERCA Biophysical Journal. 102: 404a. DOI: 10.1016/J.Bpj.2011.11.2206  0.784
2012 Fruen BR, Nitu F, Nguyen T, Oda T, Yang Y, Thomas DD, Bers DM, Cornea RL. FRET Detection of RyR2 Calmodulin Binding and Calcium-Dependent Modulation by RyR22460-2495 Peptide (DPc10) Biophysical Journal. 102: 306a. DOI: 10.1016/J.Bpj.2011.11.1689  0.392
2011 Espinoza-Fonseca LM, Thomas DD. Atomic-level characterization of the activation mechanism of serca by calcium Plos One. 6. PMID 22046418 DOI: 10.1371/Journal.Pone.0026936  0.399
2011 Klein JC, Moen RJ, Smith EA, Titus MA, Thomas DD. Structural and functional impact of site-directed methionine oxidation in myosin. Biochemistry. 50: 10318-27. PMID 21988699 DOI: 10.1021/Bi201279U  0.812
2011 Prochniewicz E, Pierre A, McCullough BR, Chin HF, Cao W, Saunders LP, Thomas DD, De La Cruz EM. Actin filament dynamics in the actomyosin VI complex is regulated allosterically by calcium-calmodulin light chain. Journal of Molecular Biology. 413: 584-92. PMID 21910998 DOI: 10.1016/J.Jmb.2011.08.058  0.435
2011 Moen RJ, Johnsrud DO, Thomas DD, Titus MA. Characterization of a myosin VII MyTH/FERM domain. Journal of Molecular Biology. 413: 17-23. PMID 21875595 DOI: 10.1016/J.Jmb.2011.08.036  0.778
2011 Lin AY, Prochniewicz E, James ZM, Svensson B, Thomas DD. Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism. Proceedings of the National Academy of Sciences of the United States of America. 108: 12729-33. PMID 21768337 DOI: 10.1073/Pnas.1106453108  0.818
2011 Autry JM, Rubin JE, Pietrini SD, Winters DL, Robia SL, Thomas DD. Oligomeric interactions of sarcolipin and the Ca-ATPase. The Journal of Biological Chemistry. 286: 31697-706. PMID 21737843 DOI: 10.1074/Jbc.M111.246843  0.829
2011 Lockamy EL, Cornea RL, Karim CB, Thomas DD. Functional and physical competition between phospholamban and its mutants provides insight into the molecular mechanism of gene therapy for heart failure. Biochemical and Biophysical Research Communications. 408: 388-92. PMID 21510919 DOI: 10.1016/J.Bbrc.2011.04.023  0.768
2011 Gustavsson M, Traaseth NJ, Karim CB, Lockamy EL, Thomas DD, Veglia G. Lipid-mediated folding/unfolding of phospholamban as a regulatory mechanism for the sarcoplasmic reticulum Ca2+-ATPase. Journal of Molecular Biology. 408: 755-65. PMID 21419777 DOI: 10.1016/J.Jmb.2011.03.015  0.81
2011 Nesmelov YE, Agafonov RV, Negrashov IV, Blakely SE, Titus MA, Thomas DD. Structural kinetics of myosin by transient time-resolved FRET. Proceedings of the National Academy of Sciences of the United States of America. 108: 1891-6. PMID 21245357 DOI: 10.1073/Pnas.1012320108  0.76
2011 Svensson B, Lockamy EL, Young HS, Thomas DD. Molecular Dynamics Simulations of the IAEDANS Fluorescent Probe Attached to the Sarcoplasmic Reticulum Ca2+-ATpase (serca) Biophysical Journal. 100: 138a. DOI: 10.1016/J.Bpj.2010.12.959  0.786
2011 Agafonov RV, Blakely S, Titus MA, Thomas DD, Nesmelov YE. Functional Mutations in the Force Generation Region Destabilize the Relay Helix in Myosin Biophysical Journal. 100: 130a. DOI: 10.1016/J.Bpj.2010.12.916  0.766
2011 Mello RN, Agafonov RV, Thompson AR, Thomas DD. High-Resolution EPR of a Bifunctional Spin Label Reveals an ADP Induced Structural Rearrangement of the Actin-Bound Myosin Catalytic Domain Biophysical Journal. 100: 130a. DOI: 10.1016/J.Bpj.2010.12.915  0.825
2011 Muretta JM, Titus MA, Thomas DD. Structural Dynamics of Myosin Investigated by Transient Time Resolved Fluorescence Biophysical Journal. 100: 129a-130a. DOI: 10.1016/J.Bpj.2010.12.912  0.402
2011 Guhathakurta P, Prochniewicz E, Muretta JM, Thomas DD. Allosteric Effects within the Catalytic Domain of Dictyostelium Myosin on Interaction with Actin and Nucleotide Biophysical Journal. 100: 594a. DOI: 10.1016/J.Bpj.2010.12.3424  0.391
2011 Colson BA, Rybakova IN, Prochniewicz E, Moss RL, Thomas DD. Effects of Cardiac Myosin Binding Protein-C and its Domains on the Rotational Dynamics of Actin Filaments Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3379  0.372
2011 Gruber SJ, Thomas DD. Structure-Based Design of Phospholamban Mutants for Treatment of Heart Failure Biophysical Journal. 100: 548a. DOI: 10.1016/J.Bpj.2010.12.3191  0.771
2011 Lockamy EL, Cornea RL, Karim CB, Thomas DD. Probing the Molecular Mechanism of SERCA-PLB Regulation by Time-Resolved FRET Biophysical Journal. 100: 467a. DOI: 10.1016/J.Bpj.2010.12.2739  0.798
2011 Li J, Karim C, Thomas DD. Structural Dynamics of SERCA and Phospholamban by TR-FRET and TIRF Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2738  0.436
2011 James ZM, Torgersen KD, Karim CB, Thomas DD. Characterizing the Phospholamban-SERCA Complex by Pulsed EPR Spectroscopy Biophysical Journal. 100: 466a. DOI: 10.1016/J.Bpj.2010.12.2737  0.833
2011 Autry JM, Rubin JE, Robia SL, Thomas DD. Oligomeric Interactions of Sarcolipin and SERCA Detected by FRET Microscopy Biophysical Journal. 100: 466a. DOI: 10.1016/J.Bpj.2010.12.2734  0.671
2011 Nitu FR, Cornea RL, Thomas DD, Fruen BR. Direct Detection of Domain Peptide Binding to the Cardiac Ryanodine Receptor (RYR2) using FRET Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2453  0.425
2011 Lin AY, Prochniewicz E, James Z, Henderson D, Ervasti J, Thomas DD. Structural Dynamics of the Actin-Binding Domains in Dystrophin and Utrophin Biophysical Journal. 100: 302a. DOI: 10.1016/J.Bpj.2010.12.1848  0.811
2011 Zudova AM, Svensson B, Espinoza-Fonseca M, Thomas DD. Molecular Dynamics Simulation of a Spin-Labeled Membrane Protein Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1442  0.419
2011 Moen RJ, Smith E, Agafonov RV, Nesmelov YE, Thomas DD. High-Resolution Myosin Structure from DEER Using a Bifunctional Spin Label Biophysical Journal. 100: 146a. DOI: 10.1016/J.Bpj.2010.12.1002  0.812
2010 Nesmelov YE, Thomas DD. Protein structural dynamics revealed by site-directed spin labeling and multifrequency EPR. Biophysical Reviews. 2: 91-99. PMID 21687819 DOI: 10.1007/S12551-010-0032-5  0.359
2010 Muretta JM, Kyrychenko A, Ladokhin AS, Kast DJ, Gillispie GD, Thomas DD. High-performance time-resolved fluorescence by direct waveform recording. The Review of Scientific Instruments. 81: 103101. PMID 21034069 DOI: 10.1063/1.3480647  0.711
2010 Cornea RL, Nitu FR, Samsó M, Thomas DD, Fruen BR. Mapping the ryanodine receptor FK506-binding protein subunit using fluorescence resonance energy transfer. The Journal of Biological Chemistry. 285: 19219-26. PMID 20404344 DOI: 10.1074/Jbc.M109.066944  0.42
2010 Kast D, Espinoza-Fonseca LM, Yi C, Thomas DD. Phosphorylation-induced structural changes in smooth muscle myosin regulatory light chain. Proceedings of the National Academy of Sciences of the United States of America. 107: 8207-12. PMID 20404208 DOI: 10.1073/Pnas.1001941107  0.751
2010 Prochniewicz E, Chin HF, Henn A, Hannemann DE, Olivares AO, Thomas DD, De La Cruz EM. Myosin isoform determines the conformational dynamics and cooperativity of actin filaments in the strongly bound actomyosin complex. Journal of Molecular Biology. 396: 501-9. PMID 19962990 DOI: 10.1016/J.Jmb.2009.11.063  0.405
2010 Quintanilha AT, Thomas DD, Swanson M. Protein-lipid interactions within purified and reconstituted cytochrome C reductase and oxidase. Biophysical Journal. 37: 68-9. PMID 19431506 DOI: 10.1016/S0006-3495(82)84603-1  0.347
2010 Haydon SM, Winters D, Autry JM, Li J, Robia SL, Thomas DD. FRET Detected Interactions of Cardiac Membrane Proteins in Living Cells Biophysical Journal. 98: 171a. DOI: 10.1016/J.Bpj.2009.12.921  0.806
2010 James ZM, Torgersen KD, Karim C, Thomas DD. Structure and Dynamics of the Phospholamban-SERCA Complex Probed by Site-Directed EPR Spectroscopy Biophysical Journal. 98: 171a. DOI: 10.1016/J.Bpj.2009.12.920  0.825
2010 Lockamy EL, Cornea RL, Karim CB, Thomas D. Probing the Mechanism of SERCA-PLB Regulation by Time-Resolved Fret Biophysical Journal. 98: 170a. DOI: 10.1016/J.Bpj.2009.12.919  0.797
2010 Li J, Karim C, Nguyen T, Thomas DD. Oligomeric Interactions in Cardiac Calcium Regulation Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.918  0.432
2010 Autry JM, Rubin JE, Winters DL, Robia SL, Thomas DD. Detection of Sarcolipin Dimerization and SERCA Binding using FRET Microscopy Biophysical Journal. 98: 170a. DOI: 10.1016/J.Bpj.2009.12.915  0.811
2010 Svensson B, Lockamy EL, Young HS, Thomas DD. Conformational Dynamics of a Fluorescent Probe Attached to the Sarcoplasmic Reticulum Ca2+-ATPase (SERCA) Studied by Molecular Simulations Biophysical Journal. 98: 169a. DOI: 10.1016/J.Bpj.2009.12.912  0.788
2010 Klein JC, Piechowski N, Titus MA, Thomas DD. Structural Impact Of Myosin Methionine Oxidation Biophysical Journal. 98: 145a. DOI: 10.1016/J.Bpj.2009.12.780  0.711
2010 Agafonov RV, Negrashov IV, Blakely SE, Titus M, Nesmelov YE, Thomas DD. Structural Basis for Uncoupling of Force Generation in the F506A Dictyostelium Myosin Revealed by Time-Resolved EPR and FRET Biophysical Journal. 98: 143a. DOI: 10.1016/J.Bpj.2009.12.770  0.776
2010 Mahaney JE, Thomas DD, Keceli G, Toscano JP, Tocchetti C, Paolocci N. Phospholabman Regulation of SERCA2a Kinetics, as Modulated by Nitroxyl Biophysical Journal. 98: 763a. DOI: 10.1016/J.Bpj.2009.12.4190  0.425
2010 Gruber SJ, Ha KN, Lockamy EL, Cornea RL, Hajjar RJ, Veglia G, Thomas DD. Structure-Based Design of Phospholamban Mutants for Gene Therapy Biophysical Journal. 98: 763a. DOI: 10.1016/J.Bpj.2009.12.4188  0.812
2010 Muretta J, Negrashov I, Kast D, Agafonov R, Guhathakurta P, Prochniewicz E, Nesmelov Y, Gillispie G, Thomas DD. A Time Resolved Fluorescence Spectrometer with Sub-Millisecond Data Acquisition Time Biophysical Journal. 98: 585a-586a. DOI: 10.1016/J.Bpj.2009.12.3182  0.801
2010 Lin AY, Prochniewicz E, Henderson D, Ervasti J, Thomas DD. Structural Dynamics of the Dystrophin-Actin and Utrophin-Actin Complexes Biophysical Journal. 98: 542a. DOI: 10.1016/J.Bpj.2009.12.2943  0.804
2010 Agafonov RV, Negrashov IV, Blakely SE, Titus MA, Nesmelov YE, Thomas DD. Structural Dynamics by Time-Reolved EPR and Transient Time-Resolved FRET: Application to Myosin Biophysical Journal. 98: 432a. DOI: 10.1016/J.Bpj.2009.12.2345  0.779
2010 Kast DJ, Espinoza-Fonseca LM, Yi C, Thomas D. TR-FRET Experiments and MD Simulations Resolve Structural States of Smooth Muscle Regulatory Light Chain Biophysical Journal. 98: 354a-355a. DOI: 10.1016/J.Bpj.2009.12.1916  0.751
2010 Mello RN, Laden A, Harris R, Anderson LJ, Thomas DD. Myosin Crosslinking and EPR Capture the Start of Force Generation in Muscle Fibers Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1878  0.806
2010 Fruen BR, Turner M, Nitu FR, Thomas DD, Cornea RL. FRET Detection of Calmodulin Binding and Structural Rearrangements Within the Cardiac RyR2 Calcium Release Channel Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1635  0.436
2010 Cornea RL, Nitu FR, Thomas DD, Fruen BR. Time-Resolved FRET Detection of Structural Distributions Involving FKBP12.6 and Calmodulin Bound Within Macromolecular RyR Channels Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1626  0.361
2010 Gruber SJ, Haydon S, Ha KN, Hajjar RJ, Veglia G, Thomas DD. Spectroscopic Design of Phospholamban Mutants to Treat Heart Failure Biophysical Journal. 98: 246a. DOI: 10.1016/J.Bpj.2009.12.1337  0.765
2010 Nesmelov YE, Agafonov RV, Negrashov IV, Blakely S, Titus MA, Thomas DD. Relay Loop Stabilizes the Force-Generating Region in Myosin Biophysical Journal. 98: 215a. DOI: 10.1016/J.Bpj.2009.12.1161  0.752
2009 Agafonov RV, Negrashov IV, Tkachev YV, Blakely SE, Titus MA, Thomas DD, Nesmelov YE. Structural dynamics of the myosin relay helix by time-resolved EPR and FRET. Proceedings of the National Academy of Sciences of the United States of America. 106: 21625-30. PMID 19966224 DOI: 10.1073/Pnas.0909757106  0.765
2009 Becucci L, Cembran A, Karim CB, Thomas DD, Guidelli R, Gao J, Veglia G. On the function of pentameric phospholamban: ion channel or storage form? Biophysical Journal. 96: L60-2. PMID 19450461 DOI: 10.1016/J.Bpj.2009.03.013  0.338
2009 Prochniewicz E, Henderson D, Ervasti JM, Thomas DD. Dystrophin and utrophin have distinct effects on the structural dynamics of actin. Proceedings of the National Academy of Sciences of the United States of America. 106: 7822-7. PMID 19416869 DOI: 10.1073/Pnas.0812007106  0.406
2009 Thomas DD, Kast D, Korman VL. Site-directed spectroscopic probes of actomyosin structural dynamics. Annual Review of Biophysics. 38: 347-69. PMID 19416073 DOI: 10.1146/Annurev.Biophys.35.040405.102118  0.777
2009 Cornea RL, Nitu F, Gruber S, Kohler K, Satzer M, Thomas DD, Fruen BR. FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 6128-33. PMID 19332786 DOI: 10.1073/Pnas.0813010106  0.76
2009 Balog EM, Lockamy EL, Thomas DD, Ferrington DA. Site-specific methionine oxidation initiates calmodulin degradation by the 20S proteasome. Biochemistry. 48: 3005-16. PMID 19231837 DOI: 10.1021/Bi802117K  0.77
2009 Espinoza-Fonseca LM, Svensson B, Thomas DD. Molecular Dynamics Simulations Reveal Intrinsic Features of SERCA Dynamics Biophysical Journal. 96: 1-4. DOI: 10.1016/J.Bpj.2008.12.645  0.37
2009 Svensson B, Espinoza-Fonseca LM, Thomas DD. Structural Dynamics Of Sarcoplasmic Reticulum Ca2+-ATPase (SERCA) Studied By Molecular Simulations Of Site-specific Labeled Protein Biophysical Journal. 96: 1-4. DOI: 10.1016/J.Bpj.2008.12.644  0.443
2009 James ZM, Torgersen KD, Karim C, Thomas DD. Structural Dynamics Of The Phospholamban-SERCA Complex By Site-Directed EPR Spectroscopy Biophysical Journal. 96: 144a. DOI: 10.1016/J.Bpj.2008.12.643  0.819
2009 Prochniewicz E, Henderson D, Lin AY, Ervasti J, Thomas DD. Dystrophin and Utrophin have Distinct Effects on the Microsecond Dynamics of Actin Biophysical Journal. 96: 128a-129a. DOI: 10.1016/J.Bpj.2008.12.577  0.801
2009 Guhathakurta P, Prochniewicz E, Thomas DD. Weak to Strong Transition at the Actin-Myosin Interface Detected by Sensitized Emission Luminescence Resonance Energy Transfer (SELRET) Biophysical Journal. 96: 125. DOI: 10.1016/J.Bpj.2008.12.558  0.367
2009 Cornea RL, Nitu F, Kohler K, Thomas DD, Fruen BR. Structural Characterization of FKBP Interactions with RyR Channels Using Site-Directed Fluorescent Labeling and FRET Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.459  0.381
2009 Thompson AR, Mello R, Yi C, Thomas DD. Measuring Myosin Light Chain Domain Orientation in the Pre-Power Stroke AlF4 States with a Bifunctional Spin Label in Skinned Muscle Fibers Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2550  0.806
2009 Kast D, Blakely SE, Svensson B, Thomas DD. Light Chain Domain Orientation Determined by Time-resolved FRET Biophysical Journal. 96: 494a. DOI: 10.1016/J.Bpj.2008.12.2549  0.749
2009 Agafonov R, Nesmelov YE, Blakely S, Titus MA, Thomas DD. Structural Dynamics of the Myosin Relay Helix Resolved by DEER and Time-Resolved FRET Biophysical Journal. 96: 493a. DOI: 10.1016/J.Bpj.2008.12.2545  0.784
2009 Muretta J, Klein JC, Kast D, Svensson B, Thomas D. Structural Dynamics Of The Actin Binding Cleft Of Dictyostelium Myosin II Analyzed By Stopped Flow Time-Resolved FRET Biophysical Journal. 96: 493a. DOI: 10.1016/J.Bpj.2008.12.2544  0.819
2009 Klein JC, Lin AY, Titus MA, Thomas DD. Myosin II Trapped In A Weak Actin-binding State Through A Chemical Crosslink Across The Actin-Binding Cleft Biophysical Journal. 96: 492a. DOI: 10.1016/J.Bpj.2008.12.2542  0.822
2009 Lockamy EL, Kast D, Negrashov I, Young HS, Thomas DD. Nucleotide Movement within SERCA Detected by FRET Resolved Simultaneously on the Nanosecond and Millisecond Time Scales Biophysical Journal. 96: 208a. DOI: 10.1016/J.Bpj.2008.12.1848  0.814
2009 Mello RN, Anderson LJ, Thompson A, Sidabras JW, Hyde JS, Thomas DD. Structural Dynamics Of Myosin'S Light Chain Domain In A Pre-power Stroke Conformation Biophysical Journal. 96: 310a. DOI: 10.1016/J.Bpj.2008.12.1545  0.809
2009 James ZM, Torgersen KD, Thompson A, Huseby M, Thomas DD. Crystalline Spin-Labeled Hemoglobin as a Model to Compare Distances Measured by DEER Spectroscopy and X-Ray Crystallography Biophysical Journal. 96: 309a. DOI: 10.1016/J.Bpj.2008.12.1543  0.793
2009 Li J, Thomas DD. Structural Dynamics of SERCA and Phospholamban by Fluorescence and Phosphorescence Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.127  0.456
2009 Nesmelov YE, Agafonov RV, Negrashov IV, Blakely S, Titus MA, Thomas DD. Transient Dynamics of the Force-Generating Domain in Myosin During the Recovery Stroke Biophysical Journal. 96: 200a. DOI: 10.1016/J.Bpj.2008.12.1077  0.765
2008 Mahaney JE, Thomas DD, Farrance IK, Froehlich JP. Intermolecular interactions in the mechanism of skeletal muscle sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1): evidence for a triprotomer. Biochemistry. 47: 13711-25. PMID 19046074 DOI: 10.1021/Bi801024A  0.391
2008 Prochniewicz E, Spakowicz D, Thomas DD. Changes in actin structural transitions associated with oxidative inhibition of muscle contraction Biochemistry. 47: 11811-11817. PMID 18855423 DOI: 10.1021/Bi801080X  0.385
2008 Thompson AR, Naber N, Wilson C, Cooke R, Thomas DD. Structural dynamics of the actomyosin complex probed by a bifunctional spin label that cross-links SH1 and SH2. Biophysical Journal. 95: 5238-46. PMID 18805936 DOI: 10.1529/Biophysj.108.138982  0.403
2008 Agafonov RV, Nesmelov YE, Titus MA, Thomas DD. Muscle and nonmuscle myosins probed by a spin label at equivalent sites in the force-generating domain. Proceedings of the National Academy of Sciences of the United States of America. 105: 13397-402. PMID 18765799 DOI: 10.1073/Pnas.0801342105  0.781
2008 Klein JC, Burr AR, Svensson B, Kennedy DJ, Allingham J, Titus MA, Rayment I, Thomas DD. Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR. Proceedings of the National Academy of Sciences of the United States of America. 105: 12867-72. PMID 18725645 DOI: 10.1073/Pnas.0802286105  0.739
2008 Espinoza-Fonseca LM, Kast D, Thomas DD. Thermodynamic and structural basis of phosphorylation-induced disorder-to-order transition in the regulatory light chain of smooth muscle myosin Journal of the American Chemical Society. 130: 12208-12209. PMID 18715003 DOI: 10.1021/Ja803143G  0.738
2008 Nesmelov YE, Agafonov RV, Burr AR, Weber RT, Thomas DD. Structure and dynamics of the force-generating domain of myosin probed by multifrequency electron paramagnetic resonance. Biophysical Journal. 95: 247-56. PMID 18339764 DOI: 10.1529/Biophysj.107.124305  0.765
2008 Winters DL, Autry JM, Svensson B, Thomas DD. Interdomain fluorescence resonance energy transfer in SERCA probed by cyan-fluorescent protein fused to the actuator domain. Biochemistry. 47: 4246-56. PMID 18338856 DOI: 10.1021/Bi702089J  0.82
2008 Prochniewicz E, Lowe DA, Spakowicz DJ, Higgins L, O'Conor K, Thompson LV, Ferrington DA, Thomas DD. Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers. American Journal of Physiology. Cell Physiology. 294: C613-26. PMID 18003749 DOI: 10.1152/Ajpcell.00232.2007  0.358
2008 Surek JT, Thomas DD. A paramagnetic molecular voltmeter Journal of Magnetic Resonance. 190: 7-25. PMID 17964835 DOI: 10.1016/J.Jmr.2007.09.020  0.799
2007 Robia SL, Campbell KS, Kelly EM, Hou Z, Winters DL, Thomas DD. Förster transfer recovery reveals that phospholamban exchanges slowly from pentamers but rapidly from the SERCA regulatory complex. Circulation Research. 101: 1123-9. PMID 17975108 DOI: 10.1161/Circresaha.107.159947  0.804
2007 Ha KN, Traaseth NJ, Verardi R, Zamoon J, Cembran A, Karim CB, Thomas DD, Veglia G. Controlling the inhibition of the sarcoplasmic Ca2+-ATPase by tuning phospholamban structural dynamics. The Journal of Biological Chemistry. 282: 37205-14. PMID 17908690 DOI: 10.1074/Jbc.M704056200  0.439
2007 Traaseth NJ, Verardi R, Torgersen KD, Karim CB, Thomas DD, Veglia G. Spectroscopic validation of the pentameric structure of phospholamban. Proceedings of the National Academy of Sciences of the United States of America. 104: 14676-81. PMID 17804809 DOI: 10.1073/Pnas.0701016104  0.815
2007 Prochniewicz E, Thompson LV, Thomas DD. Age-related decline in actomyosin structure and function. Experimental Gerontology. 42: 931-8. PMID 17706387 DOI: 10.1016/J.Exger.2007.06.015  0.356
2007 Nesmelov YE, Karim CB, Song L, Fajer PG, Thomas DD. Rotational dynamics of phospholamban determined by multifrequency electron paramagnetic resonance. Biophysical Journal. 93: 2805-12. PMID 17573437 DOI: 10.1529/Biophysj.107.108910  0.391
2007 Espinoza-Fonseca LM, Kast D, Thomas DD. Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin Biophysical Journal. 93: 2083-2090. PMID 17545237 DOI: 10.1529/Biophysj.106.095802  0.756
2007 Karim CB, Zhang Z, Thomas DD. Synthesis of TOAC spin-labeled proteins and reconstitution in lipid membranes Nature Protocols. 2: 42-49. PMID 17401337 DOI: 10.1038/Nprot.2007.2  0.329
2007 Zhang Z, Remmer HA, Thomas DD, Karim CB. Backbone dynamics determined by electron paramagnetic resonance to optimize solid-phase peptide synthesis of TOAC-labeled phospholamban. Biopolymers. 88: 29-35. PMID 17066471 DOI: 10.1002/Bip.20618  0.314
2006 Lowe DA, Williams BO, Thomas DD, Grange RW. Molecular and cellular contractile dysfunction of dystrophic muscle from young mice. Muscle & Nerve. 34: 92-100. PMID 16634063 DOI: 10.1002/Mus.20562  0.353
2006 Karim CB, Zhang Z, Howard EC, Torgersen KD, Thomas DD. Phosphorylation-dependent conformational switch in spin-labeled phospholamban bound to SERCA. Journal of Molecular Biology. 358: 1032-40. PMID 16574147 DOI: 10.1016/J.Jmb.2006.02.051  0.828
2006 Traaseth NJ, Thomas DD, Veglia G. Effects of Ser16 phosphorylation on the allosteric transitions of phospholamban/Ca(2+)-ATPase complex. Journal of Molecular Biology. 358: 1041-50. PMID 16564056 DOI: 10.1016/J.Jmb.2006.02.047  0.423
2006 Buffy JJ, Buck-Koehntop BA, Porcelli F, Traaseth NJ, Thomas DD, Veglia G. Defining the intramembrane binding mechanism of sarcolipin to calcium ATPase using solution NMR spectroscopy. Journal of Molecular Biology. 358: 420-9. PMID 16519897 DOI: 10.1016/J.Jmb.2006.02.005  0.446
2006 Zhang J, Wallar BJ, Popescu CV, Renner DB, Thomas DD, Lipscomb JD. Methane monooxygenase hydroxylase and B component interactions. Biochemistry. 45: 2913-26. PMID 16503646 DOI: 10.1021/Bi052256T  0.407
2006 Korman VL, Anderson SE, Prochniewicz E, Titus MA, Thomas DD. Structural dynamics of the actin-myosin interface by site-directed spectroscopy. Journal of Molecular Biology. 356: 1107-17. PMID 16406406 DOI: 10.1016/J.Jmb.2005.10.024  0.433
2006 Balog EM, Norton LE, Thomas DD, Fruen BR. Role of calmodulin methionine residues in mediating productive association with cardiac ryanodine receptors. American Journal of Physiology. Heart and Circulatory Physiology. 290: H794-9. PMID 16199479 DOI: 10.1152/Ajpheart.00706.2005  0.367
2005 Prochniewicz E, Janson N, Thomas DD, De la Cruz EM. Cofilin increases the torsional flexibility and dynamics of actin filaments. Journal of Molecular Biology. 353: 990-1000. PMID 16213521 DOI: 10.1016/J.Jmb.2005.09.021  0.391
2005 Prochniewicz E, Thomas DD, Thompson LV. Age-related decline in actomyosin function. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 425-31. PMID 15933379 DOI: 10.1093/Gerona/60.4.425  0.323
2005 Zamoon J, Nitu F, Karim C, Thomas DD, Veglia G. Mapping the interaction surface of a membrane protein: unveiling the conformational switch of phospholamban in calcium pump regulation. Proceedings of the National Academy of Sciences of the United States of America. 102: 4747-52. PMID 15781867 DOI: 10.1073/Pnas.0406039102  0.394
2005 Robia SL, Flohr NC, Thomas DD. Phospholamban pentamer quaternary conformation determined by in-gel fluorescence anisotropy. Biochemistry. 44: 4302-11. PMID 15766259 DOI: 10.1021/Bi0478446  0.641
2005 Paterlini MG, Thomas DD. The α-helical propensity of the cytoplasmic domain of phospholamban: A molecular dynamics simulation of the effect of phosphorylation and mutation Biophysical Journal. 88: 3243-3251. PMID 15764655 DOI: 10.1529/Biophysj.104.054460  0.362
2005 Nelson WD, Blakely SE, Nesmelov YE, Thomas DD. Site-directed spin labeling reveals a conformational switch in the phosphorylation domain of smooth muscle myosin Proceedings of the National Academy of Sciences of the United States of America. 102: 4000-4005. PMID 15753305 DOI: 10.1073/Pnas.0401664102  0.423
2005 Fruen BR, Balog EM, Schafer J, Nitu FR, Thomas DD, Cornea RL. Direct detection of calmodulin tuning by ryanodine receptor channel targets using a Ca2+-sensitive acrylodan-labeled calmodulin. Biochemistry. 44: 278-84. PMID 15628869 DOI: 10.1021/Bi048246U  0.379
2004 Mueller B, Zhao M, Negrashov IV, Bennett R, Thomas DD. SERCA Structural Dynamics Induced by ATP and Calcium Biochemistry. 43: 12846-12854. PMID 15461457 DOI: 10.1021/Bi0489457  0.436
2004 Karim CB, Kirby TL, Zhang Z, Nesmelov Y, Thomas DD. Phospholamban structural dynamics in lipid bilayers probed by a spin label rigidly coupled to the peptide backbone. Proceedings of the National Academy of Sciences of the United States of America. 101: 14437-42. PMID 15448204 DOI: 10.1073/Pnas.0402801101  0.811
2004 Prochniewicz E, Walseth TF, Thomas DD. Structural dynamics of actin during active interaction with myosin: different effects of weakly and strongly bound myosin heads. Biochemistry. 43: 10642-52. PMID 15311925 DOI: 10.1021/Bi049914E  0.423
2004 Metcalfe EE, Zamoon J, Thomas DD, Veglia G. (1)H/(15)N heteronuclear NMR spectroscopy shows four dynamic domains for phospholamban reconstituted in dodecylphosphocholine micelles. Biophysical Journal. 87: 1205-14. PMID 15298923 DOI: 10.1529/Biophysj.103.038844  0.388
2004 Mueller B, Karim CB, Negrashov IV, Kutchai H, Thomas DD. Direct detection of phospholamban and sarcoplasmic reticulum Ca-ATPase interaction in membranes using fluorescence resonance energy transfer. Biochemistry. 43: 8754-65. PMID 15236584 DOI: 10.1021/Bi049732K  0.405
2004 Kirby TL, Karim CB, Thomas DD. Electron Paramagnetic Resonance Reveals a Large-Scale Conformational Change in the Cytoplasmic Domain of Phospholamban upon Binding to the Sarcoplasmic Reticulum Ca-ATPase Biochemistry. 43: 5842-5852. PMID 15134458 DOI: 10.1021/Bi035749B  0.814
2004 Mahaney JE, Thomas DD, Froehlich JP. The time-dependent distribution of phosphorylated intermediates in native sarcoplasmic reticulum Ca2+-ATPase from skeletal muscle is not compatible with a linear kinetic model. Biochemistry. 43: 4400-16. PMID 15065885 DOI: 10.1021/Bi035068G  0.353
2004 Lowe DA, Warren GL, Snow LM, Thompson LV, Thomas DD. Muscle activity and aging affect myosin structural distribution and force generation in rat fibers. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 498-506. PMID 14514706 DOI: 10.1152/Japplphysiol.00842.2003  0.363
2003 Zamoon J, Mascioni A, Thomas DD, Veglia G. NMR solution structure and topological orientation of monomeric phospholamban in dodecylphosphocholine micelles. Biophysical Journal. 85: 2589-98. PMID 14507721 DOI: 10.1016/S0006-3495(03)74681-5  0.415
2003 LaConte LE, Baker JE, Thomas DD. Transient kinetics and mechanics of myosin's force-generating rotation in muscle: resolution of millisecond rotational transitions in the spin-labeled myosin light-chain domain. Biochemistry. 42: 9797-803. PMID 12911323 DOI: 10.1021/Bi034288R  0.799
2003 Buck B, Zamoon J, Kirby TL, DeSilva TM, Karim C, Thomas D, Veglia G. Overexpression, purification, and characterization of recombinant Ca-ATPase regulators for high-resolution solution and solid-state NMR studies. Protein Expression and Purification. 30: 253-61. PMID 12880775 DOI: 10.1016/S1046-5928(03)00127-X  0.816
2003 Lockwood NA, Tu RS, Zhang Z, Tirrell MV, Thomas DD, Karim CB. Structure and function of integral membrane protein domains resolved by peptide-amphiphiles: application to phospholamban. Biopolymers. 69: 283-92. PMID 12833255 DOI: 10.1002/Bip.10365  0.334
2003 Reddy LG, Cornea RL, Winters DL, McKenna E, Thomas DD. Defining the molecular components of calcium transport regulation in a reconstituted membrane system. Biochemistry. 42: 4585-92. PMID 12693956 DOI: 10.1021/Bi026995A  0.794
2003 Balog EM, Norton LE, Bloomquist RA, Cornea RL, Black DJ, Louis CF, Thomas DD, Fruen BR. Calmodulin oxidation and methionine to glutamine substitutions reveal methionine residues critical for functional interaction with ryanodine receptor-1. The Journal of Biological Chemistry. 278: 15615-21. PMID 12586832 DOI: 10.1074/Jbc.M209180200  0.37
2002 Lidke DS, Thomas DD. Coordination of the two heads of myosin during muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 99: 14801-6. PMID 12417762 DOI: 10.1073/Pnas.232161999  0.656
2002 LaConte LE, Voelz V, Nelson W, Enz M, Thomas DD. Molecular dynamics simulation of site-directed spin labeling: experimental validation in muscle fibers. Biophysical Journal. 83: 1854-66. PMID 12324407 DOI: 10.1016/S0006-3495(02)73950-7  0.788
2002 Nocek JM, Hatch SL, Seifert JL, Hunter GW, Thomas DD, Hoffman BM. Interprotein electron transfer in a confined space: uncoupling protein dynamics from electron transfer by sol-gel encapsulation. Journal of the American Chemical Society. 124: 9404-11. PMID 12167035 DOI: 10.1021/Ja0258430  0.454
2002 Mascioni A, Karim C, Zamoon J, Thomas DD, Veglia G. Solid-state NMR and rigid body molecular dynamics to determine domain orientations of monomeric phospholamban. Journal of the American Chemical Society. 124: 9392-3. PMID 12167032 DOI: 10.1021/Ja026507M  0.344
2002 Lowe DA, Thomas DD, Thompson LV. Force generation, but not myosin ATPase activity, declines with age in rat muscle fibers. American Journal of Physiology. Cell Physiology. 283: C187-92. PMID 12055087 DOI: 10.1152/Ajpcell.00008.2002  0.326
2002 Thomas DD, Prochniewicz E, Roopnarine O. Changes in actin and myosin structural dynamics due to their weak and strong interactions. Results and Problems in Cell Differentiation. 36: 7-19. PMID 11892285 DOI: 10.1007/978-3-540-46558-4_2  0.775
2002 Mascioni A, Karim C, Barany G, Thomas DD, Veglia G. Structure and orientation of sarcolipin in lipid environments. Biochemistry. 41: 475-82. PMID 11781085 DOI: 10.1021/Bi011243M  0.418
2002 Lowe DA, Warren GL, Snow LM, Thomas DD, Thompson LV. DOES MYOSIN STRUCTURE AND FUNCTION CHANGE WITH INCREASED OR DECREASED MUSCLE ACTIVITY? Medicine & Science in Sports & Exercise. 34: S186. DOI: 10.1097/00005768-200205001-01043  0.329
2001 Prochniewicz E, Thomas DD. Site-specific mutations in the myosin binding sites of actin affect structural transitions that control myosin binding Biochemistry. 40: 13933-13940. PMID 11705383 DOI: 10.1021/Bi010893N  0.363
2001 Nesmelov YE, Surek JT, Thomas DD. Enhanced EPR sensitivity from a ferroelectric cavity insert Journal of Magnetic Resonance. 153: 7-14. PMID 11700076 DOI: 10.1006/Jmre.2001.2415  0.775
2001 Karim CB, Paterlini MG, Reddy LG, Hunter GW, Barany G, Thomas DD. Role of cysteine residues in structural stability and function of a transmembrane helix bundle. The Journal of Biological Chemistry. 276: 38814-9. PMID 11477077 DOI: 10.1074/Jbc.M104006200  0.355
2001 Hellstern S, Pegoraro S, Karim CB, Lustig A, Thomas DD, Moroder L, Engel J. Sarcolipin, the shorter homologue of phospholamban, forms oligomeric structures in detergent micelles and in liposomes. The Journal of Biological Chemistry. 276: 30845-52. PMID 11413134 DOI: 10.1074/Jbc.M102495200  0.402
2001 Orlova A, Rybakova IN, Prochniewicz E, Thomas DD, Ervasti JM, Egelman EH. Binding of dystrophin's tandem calponin homology domain to F-actin is modulated by actin's structure. Biophysical Journal. 80: 1926-31. PMID 11259305 DOI: 10.1016/S0006-3495(01)76162-0  0.37
2001 Thompson LV, Lowe DA, Ferrington DA, Thomas DD. Electron paramagnetic resonance: A high-resolution tool for muscle physiology Exercise and Sport Sciences Reviews. 29: 3-6. PMID 11210444 DOI: 10.1097/00003677-200101000-00002  0.395
2001 Lowe DA, Surer JT, Thomas DD, Thompson LV. Electron paramagnetic resonance reveals age-related myosin structural changes in rat skeletal muscle fibers American Journal of Physiology - Cell Physiology. 280. PMID 11171573 DOI: 10.1152/Ajpcell.2001.280.3.C540  0.357
2000 Baker JE, LaConte LE, Thomas DD, Brust-Mascher I. Muscle chemistry and force. Biophysical Journal. 79: 1687-8. PMID 11041630 DOI: 10.1016/S0006-3495(00)76419-8  0.76
2000 Thomas D, Tovey SC, Collins TJ, Bootman MD, Berridge MJ, Lipp P. A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals. Cell Calcium. 28: 213-23. PMID 11032777 DOI: 10.1054/Ceca.2000.0152  0.37
2000 Baker JE, Thomas DD. A thermodynamic muscle model and a chemical basis for A.V. Hill's muscle equation Journal of Muscle Research and Cell Motility. 21: 335-344. PMID 11032344 DOI: 10.1023/A:1005615925390  0.331
2000 Karim CB, Marquardt CG, Stamm JD, Barany G, Thomas DD. Synthetic null-cysteine phospholamban analogue and the corresponding transmembrane domain inhibit the Ca-ATPase. Biochemistry. 39: 10892-7. PMID 10978176 DOI: 10.1021/Bi0003543  0.811
2000 Baker JE, Brust-Mascher I, LaConte LE, Thomas DD. Mechanochemical coupling in muscle. Biophysical Journal. 78: 2730. PMID 10877547 DOI: 10.1016/S0006-3495(00)76817-2  0.769
2000 Bootman MD, Thomas D, Tovey SC, Berridge MJ, Lipp P. Nuclear calcium signalling. Cellular and Molecular Life Sciences : Cmls. 57: 371-8. PMID 10823238 DOI: 10.1007/Pl00000699  0.321
2000 Thomas D, Lipp P, Tovey SC, Berridge MJ, Li W, Tsien RY, Bootman MD. Microscopic properties of elementary Ca2+ release sites in non-excitable cells. Current Biology : Cb. 10: 8-15. PMID 10660296 DOI: 10.1016/S0960-9822(99)00258-4  0.326
1999 Prochniewicz E, Thomas DD. Differences in structural dynamics of muscle and yeast actin accompany differences in functional interactions with myosin Biochemistry. 38: 14860-14867. PMID 10555968 DOI: 10.1021/Bi991343G  0.438
1999 Baker JE, LaConte LE, Brust-Mascher I, Thomas DD. Mechanochemical coupling in spin-labeled, active, isometric muscle. Biophysical Journal. 77: 2657-64. PMID 10545366 DOI: 10.1016/S0006-3495(99)77100-6  0.776
1999 Brust-Mascher I, LaConte LE, Baker JE, Thomas DD. Myosin light-chain domain rotates upon muscle activation but not ATP hydrolysis. Biochemistry. 38: 12607-13. PMID 10504229 DOI: 10.1021/Bi9905967  0.793
1999 Karon BS, Autry JM, Shi Y, Garnett CE, Inesi G, Jones LR, Kutchai H, Thomas DD. Different anesthetic sensitivities of skeletal and cardiac isoforms of the Ca-ATPase. Biochemistry. 38: 9301-7. PMID 10413504 DOI: 10.1021/Bi990190U  0.372
1999 Ramachandran S, Thomas DD. Rotational dynamics of the regulatory light chain in scallop muscle detected by time-resolved phosphorescence anisotropy Biochemistry. 38: 9097-9104. PMID 10413484 DOI: 10.1021/Bi9902945  0.397
1999 Reddy LG, Shi Y, Kutchai H, Filoteo AG, Penniston JT, Thomas DD. An autoinhibitory peptide from the erythrocyte Ca-ATPase aggregates and inhibits both muscle Ca-ATPase isoforms. Biophysical Journal. 76: 3058-65. PMID 10354431 DOI: 10.1016/S0006-3495(99)77458-8  0.366
1999 Li M, Reddy LG, Bennett R, Silva ND, Jones LR, Thomas DD. A fluorescence energy transfer method for analyzing protein oligomeric structure: application to phospholamban. Biophysical Journal. 76: 2587-99. PMID 10233073 DOI: 10.1016/S0006-3495(99)77411-4  0.42
1999 Reddy LG, Jones LR, Thomas DD. Depolymerization of phospholamban in the presence of calcium pump: a fluorescence energy transfer study. Biochemistry. 38: 3954-62. PMID 10194307 DOI: 10.1021/Bi981795D  0.438
1999 Reddy LG, Autry JM, Jones LR, Thomas DD. Co-reconstitution of phospholamban mutants with the Ca-ATPase reveals dependence of inhibitory function on phospholamban structure. The Journal of Biological Chemistry. 274: 7649-55. PMID 10075652 DOI: 10.1074/Jbc.274.12.7649  0.393
1999 Manoj N, Srinivas VR, Surolia A, Vijayan M, Suguna K, Ravishankar R, Schwarzenbacher R, Zeth K, Diederichs, Kostner GM, Gries A, Laggner P, Prassl R, Madhusudan, Akamine P, ... ... Thomas DD, et al. Contributory presentations/posters Journal of Biosciences. 24: 33-198. DOI: 10.1007/Bf02989373  0.473
1998 Thomas DD, Reddy LG, Karim CB, Li M, Cornea R, Autry JM, Jones LR, Stamm J. Direct spectroscopic detection of molecular dynamics and interactions of the calcium pump and phospholamban. Annals of the New York Academy of Sciences. 853: 186-94. PMID 10603946 DOI: 10.1111/J.1749-6632.1998.Tb08266.X  0.836
1998 Roopnarine O, Szent-Györgyi AG, Thomas DD. Microsecond rotational dynamics of spin-labeled myosin regulatory light chain induced by relaxation and contraction of scallop muscle. Biochemistry. 37: 14428-36. PMID 9772169 DOI: 10.1021/Bi9808363  0.77
1998 Karim CB, Stamm JD, Karim J, Jones LR, Thomas DD. Cysteine reactivity and oligomeric structures of phospholamban and its mutants. Biochemistry. 37: 12074-81. PMID 9724519 DOI: 10.1021/Bi980642N  0.809
1998 Li M, Cornea RL, Autry JM, Jones LR, Thomas DD. Phosphorylation-induced structural change in phospholamban and its mutants, detected by intrinsic fluorescence. Biochemistry. 37: 7869-77. PMID 9601048 DOI: 10.1021/Bi9801053  0.411
1998 Baker JE, Brust-Mascher I, Ramachandran S, LaConte LE, Thomas DD. A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 95: 2944-9. PMID 9501195 DOI: 10.1073/Pnas.95.6.2944  0.8
1998 Kutchai H, Geddis LM, Jones LR, Thomas DD. Differential effects of general anesthetics on the quaternary structure of the Ca-ATPases of cardiac and skeletal sarcoplasmic reticulum Biochemistry. 37: 2410-2421. PMID 9485389 DOI: 10.1021/Bi9722002  0.371
1997 Lipp P, Thomas D, Berridge MJ, Bootman MD. Nuclear calcium signalling by individual cytoplasmic calcium puffs. The Embo Journal. 16: 7166-73. PMID 9384593 DOI: 10.1093/Emboj/16.23.7166  0.336
1997 Prochniewicz E, Thomas DD. Perturbations of functional interactions with myosin induce long-range allosteric and cooperative structural changes in actin Biochemistry. 36: 12845-12853. PMID 9335542 DOI: 10.1021/Bi971201R  0.396
1997 Cornea RL, Jones LR, Autry JM, Thomas DD. Mutation and phosphorylation change the oligomeric structure of phospholamban in lipid bilayers Biochemistry. 36: 2960-2967. PMID 9062126 DOI: 10.1021/Bi961955Q  0.375
1997 Kleinschmidt JH, Mahaney JE, Thomas DD, Marsh D. Interaction of bee venom melittin with zwitterionic and negatively charged phospholipid bilayers: a spin-label electron spin resonance study. Biophysical Journal. 72: 767-78. PMID 9017202 DOI: 10.1016/S0006-3495(97)78711-3  0.357
1996 Shi Y, Karon BS, Kutchai H, Thomas DD. Phospholamban-dependent effects of C12E8 on calcium transport and molecular dynamics in cardiac sarcoplasmic reticulum Biochemistry. 35: 13393-13399. PMID 8873607 DOI: 10.1021/Bi9614085  0.355
1996 Roopnarine O, Thomas DD. Orientation of intermediate nucleotide states of indane dione spin-labeled myosin heads in muscle fibers. Biophysical Journal. 70: 2795-806. PMID 8744317 DOI: 10.1016/S0006-3495(96)79849-1  0.773
1996 Prochniewicz E, Zhang Q, Janmey PA, Thomas DD. Cooperativity in F-actin: Binding of gelsolin at the barbed end affects structure and dynamics of the whole filament Journal of Molecular Biology. 260: 756-766. PMID 8709153 DOI: 10.1006/Jmbi.1996.0435  0.392
1996 Prochniewicz E, Zhang Q, Howard EC, Thomas DD. Microsecond rotational dynamics of actin: spectroscopic detection and theoretical simulation. Journal of Molecular Biology. 255: 446-57. PMID 8568889 DOI: 10.1006/Jmbi.1996.0037  0.33
1995 Thomas DD, Ramachandran S, Roopnarine O, Hayden DW, Ostap EM, Rayment I, Reisler K, Kinosita K. The mechanism of force generation in myosin: A disorder-to-order transition, coupled to internal structural changes Biophysical Journal. 68: 135s-141s. PMID 7787056  0.325
1995 Roopnarine O, Thomas DD. Orientational dynamics of indane dione spin-labeled myosin heads in relaxed and contracting skeletal muscle fibers. Biophysical Journal. 68: 1461-71. PMID 7787032 DOI: 10.1016/S0006-3495(95)80319-X  0.767
1995 Karon BS, Geddis LM, Kutchai H, Thomas DD. Anesthetics alter the physical and functional properties of the Ca-ATPase in cardiac sarcoplasmic reticulum Biophysical Journal. 68: 936-945. PMID 7756557 DOI: 10.1016/S0006-3495(95)80269-9  0.363
1995 Mahaney JE, Froehlich JP, Thomas DD. Conformational transitions of the sarcoplasmic reticulum Ca-ATPase studied by time-resolved EPR and quenched-flow kinetics. Biochemistry. 34: 4864-79. PMID 7718593 DOI: 10.1021/Bi00014A044  0.41
1995 Mersol JV, Kutchai H, Mahaney JE, Thomas DD. Self-association accompanies inhibition of Ca-ATPase by thapsigargin Biophysical Journal. 68: 208-215. PMID 7711243 DOI: 10.1016/S0006-3495(95)80176-1  0.382
1995 Ostap EM, Barnett VA, Thomas DD. Resolution of three structural states of spin-labeled myosin in contracting muscle. Biophysical Journal. 69: 177-88. PMID 7669895 DOI: 10.1016/S0006-3495(95)79888-5  0.451
1995 Voss JC, Mahaney JE, Jones LR, Thomas DD. Molecular dynamics in mouse atrial tumor sarcoplasmic reticulum Biophysical Journal. 68: 1787-1795. PMID 7612820 DOI: 10.1016/S0006-3495(95)80355-3  0.388
1995 Karon BS, Nissen ER, Voss J, Thomas DD. A Continuous Spectrophotometric Assay for Simultaneous Measurement of Calcium Uptake and ATP Hydrolysis in Sarcoplasmic Reticulum Analytical Biochemistry. 227: 328-333. PMID 7573954 DOI: 10.1006/Abio.1995.1288  0.364
1994 Thomas DD. Effects of membrane thickness on the molecular dynamics and enzymatic activity of reconstituted Ca-ATPase Biochemistry. 33: 2912-2920. PMID 8130205 DOI: 10.1021/Bi00176A022  0.395
1994 Karon BS, Mahaney JE, Thomas DD. Halothane and cyclopiazonic acid modulate Ca-ATPase oligomeric state and function in sarcoplasmic reticulum Biochemistry. 33: 13928-13937. PMID 7947799 DOI: 10.1021/Bi00250A048  0.374
1994 Kutchai H, Mahaney JE, Geddis LM, Thomas DD. Hexanol and lidocaine affect the oligomeric state of the Ca-ATPase of sarcoplasmic reticulum. Biochemistry. 33: 13208-22. PMID 7947728 DOI: 10.1021/Bi00249A007  0.389
1994 Berger CL, Thomas DD. Rotational dynamics of actin-bound intermediates of the myosin adenosine triphosphatase cycle in myofibrils. Biophysical Journal. 67: 250-61. PMID 7918993 DOI: 10.1016/S0006-3495(94)80476-X  0.405
1994 Voss J, Jones LR, Thomas DD. The physical mechanism of calcium pump regulation in the heart Biophysical Journal. 67: 190-196. PMID 7918987 DOI: 10.1016/S0006-3495(94)80469-2  0.397
1994 Roopnarine O, Thomas DD. A spin label that binds to myosin heads in muscle fibers with its principal axis parallel to the fiber axis. Biophysical Journal. 67: 1634-45. PMID 7819495 DOI: 10.1016/S0006-3495(94)80636-8  0.748
1993 Thomas DD, Gaffney BJ, Griffith H. Harden M. McConnell: The Science Speaks for Itself. Biophysical Journal. 64: 573-6. PMID 19431875 DOI: 10.1016/S0006-3495(93)81415-2  0.564
1993 Roopnarine O, Hideg K, Thomas DD. Saturation transfer electron parametric resonance of an indane-dione spin-label. Calibration with hemoglobin and application to myosin rotational dynamics. Biophysical Journal. 64: 1896-907. PMID 8396449 DOI: 10.1016/S0006-3495(93)81561-3  0.765
1993 Birmachu W, Voss JC, Louis CF, Thomas DD. Protein and lipid rotational dynamics in cardiac and skeletal sarcoplasmic reticulum detected by EPR and phosphorescence anisotropy Biochemistry®. 32: 9445-9453. PMID 8396431 DOI: 10.1021/Bi00087A024  0.416
1993 Thomas DD. Molecular mechanism of Ca-ATPase activation by halothane in sarcoplasmic reticulum Biochemistry. 32: 7503-7511. PMID 8393342 DOI: 10.1021/Bi00080A023  0.326
1993 Ostap EM, White HD, Thomas DD. Transient detection of spin-labeled myosin subfragment 1 conformational states during ATP hydrolysis. Biochemistry. 32: 6712-20. PMID 8392368 DOI: 10.1021/Bi00077A026  0.409
1993 Howard EC, Lindahl KM, Polnaszek CF, Thomas DD. Simulation of saturation transfer electron paramagnetic resonance spectra for rotational motion with restricted angular amplitude. Biophysical Journal. 64: 581-93. PMID 8386008 DOI: 10.1016/S0006-3495(93)81417-6  0.312
1993 Berger CL, Thomas DD. Rotational dynamics of actin-bound myosin heads in active myofibrils. Biochemistry. 32: 3812-21. PMID 8385491 DOI: 10.1021/Bi00065A038  0.398
1993 Thomas DD. Pollard to actomyosin: 'Freeze! Don't even move your head' Biophysical Journal. 64: 297-298. PMID 8384499 DOI: 10.1016/S0006-3495(93)81367-5  0.381
1993 Prochniewicz E, Katayama E, Yanagida T, Thomas DD. Cooperativity in F-actin: Chemical modifications of actin monomers affect the functional interactions of myosin with unmodified monomers in the same actin filament Biophysical Journal. 65: 113-123. PMID 8369420 DOI: 10.1016/S0006-3495(93)81057-9  0.348
1993 Thomas DD, Mahaney JE. Chapter 12 The functional effects of protein and lipid dynamics in sarcoplasmic reticulum New Comprehensive Biochemistry. 25: 301-320. DOI: 10.1016/S0167-7306(08)60241-0  0.365
1992 Tanner JW, Thomas DD, Goldman YE. Transients in orientation of a fluorescent cross-bridge probe following photolysis of caged nucleotides in skeletal muscle fibres. Journal of Molecular Biology. 223: 185-203. PMID 1530978 DOI: 10.1016/0022-2836(92)90725-Y  0.391
1992 Mahaney JE, Kleinschmidt J, Marsh D, Thomas DD. Effects of melittin on lipid-protein interactions in sarcoplasmic reticulum membranes. Biophysical Journal. 63: 1513-22. PMID 1336987 DOI: 10.1016/S0006-3495(92)81736-8  0.367
1992 Ostap EM, Yanagida T, Thomas DD. Orientational distribution of spin-labeled actin oriented by flow. Biophysical Journal. 63: 966-75. PMID 1330042 DOI: 10.1016/S0006-3495(92)81684-3  0.372
1992 Alessi DR, Corrie JE, Fajer PG, Ferenczi MA, Thomas DD, Trayer IP, Trentham DR. Synthesis and properties of a conformationally restricted spin-labeled analog of ATP and its interaction with myosin and skeletal muscle. Biochemistry. 31: 8043-54. PMID 1324724 DOI: 10.1021/Bi00149A039  0.414
1991 Fajer PG, Fajer EA, Schoenberg M, Thomas DD. Orientational disorder and motion of weakly attached cross-bridges Biophysical Journal. 60: 642-649. PMID 1657230 DOI: 10.1016/S0006-3495(91)82093-8  0.336
1991 Berger CL, Thomas DD. Rotational dynamics of actin-bound intermediates in the myosin ATPase cycle. Biochemistry. 30: 11036-45. PMID 1657157 DOI: 10.1021/Bi00110A005  0.407
1991 Ostap EM, Thomas DD. Rotational dynamics of spin-labeled F-actin during activation of myosin S1 ATPase using caged ATP. Biophysical Journal. 59: 1235-41. PMID 1651780 DOI: 10.1016/S0006-3495(91)82338-4  0.39
1991 Thomas DD. Effects of melittin on molecular dynamics and Ca-ATPase activity in sarcoplasmic reticulum membranes: Time-resolved optical anisotropy Biochemistry®. 30: 7498-7506. PMID 1649630 DOI: 10.1021/Bi00244A019  0.408
1991 Thomas DD. Effects of Melittin on Molecular Dynamics and Ca-ATPase Activity in Sarcoplasmic Reticulum Membranes: Electron Paramagnetic Resonance Biochemistry®. 30: 7171-7180. PMID 1649624 DOI: 10.1021/Bi00243A019  0.424
1990 Fajer PG, Fajer EA, Thomas DD. Myosin heads have a broad orientational distribution during isometric muscle contraction: Time-resolved EPR studies using caged ATP Proceedings of the National Academy of Sciences of the United States of America. 87: 5538-5542. PMID 2164688 DOI: 10.1073/Pnas.87.14.5538  0.398
1990 Harada Y, Sakurada K, Aoki T, Thomas DD, Yanagida T. Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay. Journal of Molecular Biology. 216: 49-68. PMID 2146398 DOI: 10.1016/S0022-2836(05)80060-9  0.345
1990 Birmachu W, Thomas DD. Rotational dynamics of the Ca-ATPase in sarcoplasmic reticulum studied by time-resolved phosphorescence anisotropy Biochemistry. 29: 3904-3914. PMID 2141280 DOI: 10.1021/Bi00468A017  0.341
1990 Stein RA, Ludescher RD, Dahlberg PS, Fajer PG, Bennett RL, Thomas DD. Time-resolved rotational dynamics of phosphorescent-labeled myosin heads in contracting muscle fibers. Biochemistry. 29: 10023-31. PMID 1703000 DOI: 10.1021/Bi00495A003  0.352
1989 Squier TC, Thomas DD. Selective detection of the rotational dynamics of the protein-associated lipid hydrocarbon chains in sarcoplasmic reticulum membranes Biophysical Journal. 56: 735-748. PMID 2554990 DOI: 10.1016/S0006-3495(89)82721-3  0.348
1989 Ervasti JM, Mickelson JR, Lewis SM, Thomas DD, Louis CF. An electron paramagnetic resonance study of skeletal muscle membrane fluidity in malignant hyperthermia. Biochimica Et Biophysica Acta. 986: 70-4. PMID 2554982 DOI: 10.1016/0005-2736(89)90273-3  0.31
1989 Berger CL, Svensson EC, Thomas DD. Photolysis of a photolabile precursor of ATP (caged ATP) induces microsecond rotational motions of myosin heads bound to actin. Proceedings of the National Academy of Sciences of the United States of America. 86: 8753-7. PMID 2554328 DOI: 10.1073/Pnas.86.22.8753  0.383
1989 Barnett VA, Thomas DD. Microsecond rotational motion of spin-labeled myosin heads during isometric muscle contraction. Saturation transfer electron paramagnetic resonance. Biophysical Journal. 56: 517-23. PMID 2551405 DOI: 10.1016/S0006-3495(89)82698-0  0.357
1989 Birmachu W, Nisswandt FL, Thomas DD. Conformational transitions in the calcium adenosinetriphosphatase studied by time-resolved fluorescence resonance energy transfer Biochemistry. 28: 3940-3947. PMID 2526653 DOI: 10.1021/Bi00435A047  0.36
1988 Fajer PG, Fajer EA, Brunsvold NJ, Thomas DD. Effects of AMPPNP on the orientation and rotational dynamics of spin-labeled muscle cross-bridges Biophysical Journal. 53: 513-524. PMID 2838098 DOI: 10.1016/S0006-3495(88)83131-X  0.392
1988 Ludescher RD, Thomas DD. Microsecond rotational dynamics of phosphorescent-labeled muscle cross-bridges. Biochemistry. 27: 3343-51. PMID 2455541 DOI: 10.1021/Bi00409A034  0.33
1988 Ludescher RD, Eads TM, Thomas DD. Ionic effects on the rotational dynamics of cross-bridges in myosin filaments, measured by triplet absorption anisotropy. Journal of Molecular Biology. 200: 89-99. PMID 2454317 DOI: 10.1016/0022-2836(88)90335-X  0.306
1987 Thomas DD. Spectroscopic probes of muscle cross-bridge rotation Annual Review of Physiology. 49: 691-709. PMID 3032079 DOI: 10.1146/Annurev.Ph.49.030187.003355  0.339
1987 Barnett VA, Thomas DD. Resolution of conformational states of spin-labeled myosin during steady-state ATP hydrolysis. Biochemistry. 26: 314-23. PMID 3030402 DOI: 10.1021/Bi00375A044  0.392
1987 Thatte HS, Addis PB, Thomas DD, Bigelow DJ, Mickelson JR, Louis CF. Temperature-dependent abnormalities of the erythrocyte membrane in porcine malignant hyperthermia Biochemical Medicine and Metabolic Biology. 38: 366-377. PMID 2829949 DOI: 10.1016/0885-4505(87)90101-0  0.319
1986 Barnett VA, Fajer P, Polnaszek CF, Thomas DD. High-Resolution Detection of muscle Crossbridge Orientation by Electron Paramagnetic Resonance. Biophysical Journal. 49: 144-7. PMID 19431623 DOI: 10.1016/S0006-3495(86)83628-1  0.304
1986 Svensson EC, Thomas DD. ATP induces microsecond rotational motions of myosin heads crosslinked to actin Biophysical Journal. 50: 999-1002. PMID 3790699 DOI: 10.1016/S0006-3495(86)83541-X  0.373
1986 Fajer P, Thomas DD, Feix JB, Hyde JS. Measurement of rotational molecular motion by time-resolved saturation transfer electron paramagnetic resonance. Biophysical Journal. 50: 1195-202. PMID 3026503 DOI: 10.1016/S0006-3495(86)83562-7  0.327
1986 Lewis SM, Thomas DD. Effects of vanadate on the rotational dynamics of spin-labeled calcium adenosinetriphosphatase in sarcoplasmic reticulum membranes Biochemistry®. 25: 4615-4621. PMID 3021193 DOI: 10.1021/Bi00364A024  0.41
1986 Squier TC, Thomas DD. Applications of new saturation transfer electron paramagnetic resonance methodology to the rotational dynamics of the Ca-ATPase in sarcoplasmic reticulum membranes Biophysical Journal. 49: 937-942. PMID 3013331 DOI: 10.1016/S0006-3495(86)83721-3  0.307
1986 Bigelow DJ, Squier TC, Thomas DD. Temperature dependence of rotational dynamics of protein and lipid in sarcoplasmic reticulum membranes Biochemistry. 25: 194-202. PMID 3006752 DOI: 10.1021/Bi00349A028  0.387
1984 Cooke R, Crowder MS, Wendt CH, Barnett VA, Thomas DD. Muscle cross-bridges: do they rotate? Advances in Experimental Medicine and Biology. 170: 413-27. PMID 6331101 DOI: 10.1007/978-1-4684-4703-3_37  0.361
1984 Eads TM, Thomas DD, Austin RH. Microsecond rotational motions of eosin-labeled myosin measured by time-resolved anisotropy of absorption and phosphorescence. Journal of Molecular Biology. 179: 55-81. PMID 6209402 DOI: 10.1016/0022-2836(84)90306-1  0.348
1984 Barnett VA, Thomas DD. Saturation transfer electron paramagnetic resonance of spin-labeled muscle fibers. Dependence of myosin head rotational motion on sarcomere length. Journal of Molecular Biology. 179: 83-102. PMID 6094826 DOI: 10.1016/0022-2836(84)90307-3  0.366
1983 Thomas DD, Wendt CH, Francisz W, Hyde JS. Saturation transfer EPR spectroscopy on spin-labeled muscle fibers using a loop-gap resonator. Biophysical Journal. 43: 131-5. PMID 6309262 DOI: 10.1016/S0006-3495(83)84332-X  0.334
1983 Thomas DD, Cooke R, Barnett VA. Orientation and rotational mobility of spin-labelled myosin heads in insect flight muscle in rigor. Journal of Muscle Research and Cell Motility. 4: 367-78. PMID 6308040 DOI: 10.1007/Bf00712002  0.374
1983 Thomas DD. Rotational dynamics of spin-labelled muscle proteins. Ciba Foundation Symposium. 93: 169-85. PMID 6301780  0.326
1982 Stryer L, Thomas DD, Carlsen WF. Fluorescence energy transfer measurements of distances in rhodopsin and the purple membrane protein. Methods in Enzymology. 81: 668-78. PMID 7098907 DOI: 10.1016/S0076-6879(82)81092-6  0.576
1982 Thomas DD, Stryer L. Transverse location of the retinal chromophore of rhodopsin in rod outer segment disc membranes. Journal of Molecular Biology. 154: 145-57. PMID 7077659 DOI: 10.1016/0022-2836(82)90422-3  0.569
1982 Stryer L, Thomas DD, Meares CF. Diffusion-enhanced fluorescence energy transfer. Annual Review of Biophysics and Bioengineering. 11: 203-22. PMID 7049062 DOI: 10.1146/annurev.bb.11.060182.001223  0.503
1982 Cooke R, Crowder MS, Thomas DD. Orientation of spin labels attached to cross-bridges in contracting muscle fibres Nature. 300: 776-778. PMID 6294531 DOI: 10.1038/300776A0  0.365
1982 Thomas DD, Bigelow DJ, Squier TC, Hidalgo C. Rotational dynamics of protein and boundary lipid in sarcoplasmic reticulum membrane Biophysical Journal. 37: 217-225. PMID 6275923 DOI: 10.1016/S0006-3495(82)84671-7  0.373
1980 Thomas DD, Cooke R. Orientation of spin-labeled myosin heads in glycerinated muscle fibers Biophysical Journal. 32: 891-906. PMID 6266539 DOI: 10.1016/S0006-3495(80)85024-7  0.319
1980 Thomas DD, Ishiwata S, Seidel JC, Gergely J. Submillisecond rotational dynamics of spin-labeled myosin heads in myofibrils Biophysical Journal. 32: 873-889. PMID 6266538 DOI: 10.1016/S0006-3495(80)85023-5  0.611
1979 Thomas DD, Seidel JC, Gergely J. Rotational dynamics of spin-labeled F-actin in the sub-millisecond time range Journal of Molecular Biology. 132: 257-273. PMID 230351 DOI: 10.1016/0022-2836(79)90259-6  0.595
1978 Thomas DD, Carlsen WF, Stryer L. Fluorescence energy transfer in the rapid-diffusion limit. Proceedings of the National Academy of Sciences of the United States of America. 75: 5746-50. PMID 16592590 DOI: 10.1073/Pnas.75.12.5746  0.563
1978 Thomas DD. Large-scale rotational motions of proteins detected by electron paramagnetic resonance and fluorescence Biophysical Journal. 24: 439-462. PMID 215240 DOI: 10.1016/S0006-3495(78)85394-6  0.358
1978 Thomas DD, Hidalgo C. Rotational motion of the sarcoplasmic reticulum Ca2+-ATPase Proceedings of the National Academy of Sciences of the United States of America. 75: 5488-5492. PMID 214789 DOI: 10.1073/Pnas.75.11.5488  0.328
1977 Hidalgo C, Thomas DD. Heterogeneity of SH group in sarcoplasmic reticulum Biochemical and Biophysical Research Communications. 78: 1175-1182. PMID 200229 DOI: 10.1016/0006-291X(77)91417-6  0.374
1977 Baroin A, Thomas DD, Osborne B, Devaux PF. Saturation transfer electron paramagnetic resonance on membrane-bound proteins. I-rotational diffusion of rhodopsin in the visual receptor membrane Biochemical and Biophysical Research Communications. 78: 442-447. PMID 199170 DOI: 10.1016/0006-291X(77)91274-8  0.314
1976 Thomas DD, Dalton LR, Hyde JS. Rotational diffusion studied by passage saturation transfer electron paramagnetic resonance The Journal of Chemical Physics. 65: 3006-3024. DOI: 10.1063/1.433512  0.31
1975 Thomas DD, Seidel JC, Gergely J, Hyde JS. The quantitative measurement of rotational motion of the subfragment-1 region of myosin by saturation transfer epr spectroscopy. Journal of Supramolecular Structure. 3: 376-90. PMID 172739 DOI: 10.1002/Jss.400030410  0.608
1975 Thomas DD, Seidel JC, Hyde JS, Gergely J. Motion of subfragment-1 in myosin and its supramolecular complexes: saturation transfer electron paramagnetic resonance. Proceedings of the National Academy of Sciences of the United States of America. 72: 1729-33. PMID 168572 DOI: 10.1073/Pnas.72.5.1729  0.625
1974 Thomas DD, McConnell HM. Calculation of paramagnetic resonance spectra sensitive to very slow rotational motion Chemical Physics Letters. 25: 470-475. DOI: 10.1016/0009-2614(74)85346-7  0.483
1965 McConnell HM, Hoffman BM, Thomas DD, Gamble FR. CHEMICAL ENHANCEMENT OF SUPERCONDUCTIVITY. Proceedings of the National Academy of Sciences of the United States of America. 54: 371-4. PMID 16591299 DOI: 10.1073/Pnas.54.2.371  0.538
1963 Thomas DD, Keller H, McConnell HM. Exciton Magnetic Resonance in Wurster's Blue Perchlorate The Journal of Chemical Physics. 39: 2321-2329. DOI: 10.1063/1.1701437  0.499
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