Anthony E. Oro - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Oncology, Cell Biology, Biochemistry

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kuonen F, Huskey NE, Shankar G, Jaju P, Whitson RJ, Rieger KE, Atwood SX, Sarin KY, Oro AE. Loss of primary cilia drives switching from Hedgehog to Ras/MAPK pathway in resistant basal cell carcinoma. The Journal of Investigative Dermatology. PMID 30707899 DOI: 10.1016/j.jid.2018.11.035  0.32
2018 Brown AS, Meera P, Altindag B, Chopra R, Perkins EM, Paul S, Scoles DR, Tarapore E, Magri J, Huang H, Jackson M, Shakkottai VG, Otis TS, Pulst SM, Atwood SX, ... Oro AE, et al. MTSS1/Src family kinase dysregulation underlies multiple inherited ataxias. Proceedings of the National Academy of Sciences of the United States of America. PMID 30530649 DOI: 10.1073/pnas.1816177115  0.32
2018 Drummond ML, Li M, Tarapore E, Nguyen TTL, Barouni BJ, Cruz S, Tan KC, Oro AE, Atwood SX. Actin polymerization controls cilia-mediated signaling. The Journal of Cell Biology. PMID 29945904 DOI: 10.1083/jcb.201703196  0.32
2018 Whitson RJ, Lee A, Urman NM, Mirza A, Yao CY, Brown AS, Li JR, Shankar G, Fry MA, Atwood SX, Lee EY, Hollmig ST, Aasi SZ, Sarin KY, Scott MP, ... ... Oro AE, et al. Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas. Nature Medicine. PMID 29400712 DOI: 10.1038/nm.4476  0.32
2017 Mirza AN, Fry MA, Urman NM, Atwood SX, Roffey J, Ott GR, Chen B, Lee A, Brown AS, Aasi SZ, Hollmig T, Ator MA, Dorsey BD, Ruggeri BR, Zificsak CA, ... ... Oro AE, et al. Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment. Jci Insight. 2. PMID 29093271 DOI: 10.1172/jci.insight.97071  0.32
2016 Urman NM, Mirza A, Atwood SX, Whitson RJ, Sarin KY, Tang JY, Oro AE. Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions. Plos One. 11: e0168031. PMID 28030567 DOI: 10.1371/journal.pone.0168031  0.32
2016 Kwon GP, Ally MS, Bailey-Healy I, Oro AE, Kim J, Chang AL, Aasi S, Tang JY. Update to an open-label clinical trial of vismodegib as neoadjuvant before surgery for high-risk basal cell carcinoma (BCC). Journal of the American Academy of Dermatology. 75: 213-5. PMID 27317518 DOI: 10.1016/j.jaad.2016.02.1235  0.56
2015 Danial C, Sarin KY, Oro AE, Chang AL. An Investigator-Initiated Open-label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26546616 DOI: 10.1158/1078-0432.CCR-15-1588  0.56
2015 Jaju PD, Nguyen CB, Mah AM, Atwood SX, Li J, Zia A, Chang AL, Oro AE, Tang JY, Lee CS, Sarin KY. Mutations in the Kinetochore Gene KNSTRN in Basal Cell Carcinoma. The Journal of Investigative Dermatology. PMID 26348826 DOI: 10.1038/jid.2015.339  0.56
2015 Zhao X, Ponomaryov T, Ornell KJ, Zhou P, Dabral SK, Pak E, Li W, Atwood SX, Whitson RJ, Chang AL, Li J, Oro AE, Chan JA, Kelleher JF, Segal RA. RAS/MAPK activation drives resistance to Smo inhibition, metastasis and tumor evolution in Shh pathway-dependent tumors. Cancer Research. PMID 26130651 DOI: 10.1158/0008-5472.CAN-14-2999-T  0.56
2015 Atwood SX, Sarin KY, Li JR, Yao CY, Urman NM, Chang AL, Tang JY, Oro AE. Rolling the Genetic Dice: Neutral and Deleterious Smoothened Mutations in Drug-Resistant Basal Cell Carcinoma. The Journal of Investigative Dermatology. 135: 2138-41. PMID 25801792 DOI: 10.1038/jid.2015.115  0.32
2015 Atwood SX, Sarin KY, Whitson RJ, Li JR, Kim G, Rezaee M, Ally MS, Kim J, Yao C, Chang AL, Oro AE, Tang JY. Smoothened variants explain the majority of drug resistance in basal cell carcinoma. Cancer Cell. 27: 342-53. PMID 25759020 DOI: 10.1016/j.ccell.2015.02.002  0.56
2014 Sebastiano V, Zhen HH, Haddad B, Derafshi BH, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, ... ... Oro AE, et al. Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Science Translational Medicine. 6: 264ra163. PMID 25429056 DOI: 10.1126/scitranslmed.3009540  0.56
2014 Atwood SX, Whitson RJ, Oro AE. Advanced treatment for basal cell carcinomas. Cold Spring Harbor Perspectives in Medicine. 4: a013581. PMID 24985127 DOI: 10.1101/cshperspect.a013581  0.56
2014 Tang Y, Gholamin S, Schubert S, Willardson MI, Lee A, Bandopadhayay P, Bergthold G, Masoud S, Nguyen B, Vue N, Balansay B, Yu F, Oh S, Woo P, Chen S, ... ... Oro AE, et al. Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition. Nature Medicine. 20: 732-40. PMID 24973920 DOI: 10.1038/nm.3613  0.56
2014 Atwood SX, Oro AE. "Atypical" regulation of Hedgehog-dependent cancers. Cancer Cell. 25: 133-4. PMID 24525228 DOI: 10.1016/j.ccr.2014.01.027  0.32
2014 Melo SP, Lisowski L, Bashkirova E, Zhen HH, Chu K, Keene DR, Marinkovich MP, Kay MA, Oro AE. Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 725-33. PMID 24390279 DOI: 10.1038/mt.2013.290  0.56
2013 Whyte JL, Smith AA, Liu B, Manzano WR, Evans ND, Dhamdhere GR, Fang MY, Chang HY, Oro AE, Helms JA. Augmenting endogenous Wnt signaling improves skin wound healing. Plos One. 8: e76883. PMID 24204695 DOI: 10.1371/journal.pone.0076883  0.56
2013 Yucel G, Altindag B, Gomez-Ospina N, Rana A, Panagiotakos G, Lara MF, Dolmetsch R, Oro AE. State-dependent signaling by Cav1.2 regulates hair follicle stem cell function. Genes & Development. 27: 1217-22. PMID 23752588 DOI: 10.1101/gad.216556.113  0.56
2013 Chang AL, Atwood SX, Tartar DM, Oro AE. Surgical excision after neoadjuvant therapy with vismodegib for a locally advanced basal cell carcinoma and resistant basal carcinomas in Gorlin syndrome. Jama Dermatology. 149: 639-41. PMID 23677114 DOI: 10.1001/jamadermatol.2013.30  0.32
2013 Atwood SX, Whitson RJ, Oro AE. "Patch"ing up our tumor signaling knowledge. The Journal of Investigative Dermatology. 133: 1131-3. PMID 23594533 DOI: 10.1038/jid.2012.506  0.56
2013 Xiao Y, Woo WM, Nagao K, Li W, Terunuma A, Mukouyama YS, Oro AE, Vogel JC, Brownell I. Perivascular hair follicle stem cells associate with a venule annulus. The Journal of Investigative Dermatology. 133: 2324-31. PMID 23558405 DOI: 10.1038/jid.2013.167  0.56
2013 Woo WM, Atwood SX, Zhen HH, Oro AE. Rapid genetic analysis of epithelial-mesenchymal signaling during hair regeneration. Journal of Visualized Experiments : Jove. e4344. PMID 23486463 DOI: 10.3791/4344  0.32
2013 Atwood SX, Li M, Lee A, Tang JY, Oro AE. GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas. Nature. 494: 484-8. PMID 23446420 DOI: 10.1038/nature11889  0.32
2012 Atwood SX, Chang AL, Oro AE. Hedgehog pathway inhibition and the race against tumor evolution. The Journal of Cell Biology. 199: 193-7. PMID 23071148 DOI: 10.1083/jcb.201207140  0.32
2012 Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, Hainsworth JD, Solomon JA, Yoo S, Arron ST, Friedlander PA, Marmur E, Rudin CM, Chang AL, Low JA, Mackey HM, et al. Efficacy and safety of vismodegib in advanced basal-cell carcinoma. The New England Journal of Medicine. 366: 2171-9. PMID 22670903 DOI: 10.1056/NEJMoa1113713  0.56
2012 Woo WM, Zhen HH, Oro AE. Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop. Genes & Development. 26: 1235-46. PMID 22661232 DOI: 10.1101/gad.187401.112  0.32
2011 Hillman RT, Feng BY, Ni J, Woo WM, Milenkovic L, Hayden Gephart MG, Teruel MN, Oro AE, Chen JK, Scott MP. Neuropilins are positive regulators of Hedgehog signal transduction. Genes & Development. 25: 2333-46. PMID 22051878 DOI: 10.1101/gad.173054.111  0.56
2011 Woo WM, Oro AE. SnapShot: hair follicle stem cells. Cell. 146: 334-334.e2. PMID 21784251 DOI: 10.1016/j.cell.2011.07.001  0.32
2010 Bershteyn M, Atwood SX, Woo WM, Li M, Oro AE. MIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling. Developmental Cell. 19: 270-83. PMID 20708589 DOI: 10.1016/j.devcel.2010.07.009  0.56
2008 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP. Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes & Development. 22: 2111-24. PMID 18676816 DOI: 10.1101/gad.1689908  0.56
2008 Huntzicker EG, Oro AE. Controlling hair follicle signaling pathways through polyubiquitination. The Journal of Investigative Dermatology. 128: 1081-7. PMID 18408747 DOI: 10.1038/sj.jid.5700957  0.56
2006 Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 103: 14842-7. PMID 17003113 DOI: 10.1073/pnas.0606857103  0.56
2006 Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK, Oro AE. Dual degradation signals control Gli protein stability and tumor formation. Genes & Development. 20: 276-81. PMID 16421275 DOI: 10.1101/gad.1380906  0.56
2005 Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, Artandi SE. Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature. 436: 1048-52. PMID 16107853 DOI: 10.1038/nature03836  0.56
2004 Callahan CA, Ofstad T, Horng L, Wang JK, Zhen HH, Coulombe PA, Oro AE. MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription Genes and Development. 18: 2724-2729. PMID 15545630 DOI: 10.1101/gad.1221804  0.56
2003 Li J, Tzu J, Chen Y, Zhang YP, Nguyen NT, Gao J, Bradley M, Keene DR, Oro AE, Miner JH, Marinkovich MP. Laminin-10 is crucial for hair morphogenesis. The Embo Journal. 22: 2400-10. PMID 12743034 DOI: 10.1093/emboj/cdg239  0.56
2003 Oro AE, Higgins K. Hair cycle regulation of Hedgehog signal reception. Developmental Biology. 255: 238-48. PMID 12648487 DOI: 10.1016/S0012-1606(02)00042-8  0.56
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