Year |
Citation |
Score |
2020 |
Rajawat YS, Humbert O, Cook SM, Radtke S, Pande D, Enstrom M, Wohlfahrt ME, Kiem HP. In vivo gene therapy for canine SCID-X1 using cocal-pseudotyped lentiviral vector. Human Gene Therapy. PMID 32741228 DOI: 10.1089/Hum.2020.127 |
0.334 |
|
2020 |
Chardin D, Paquet M, Schiappa R, Darcourt J, Bailleux C, Poudenx M, Sciazza A, Ilie M, Benzaquen J, Martin N, Otto J, Humbert O. Baseline metabolic tumor volume as a strong predictive and prognostic biomarker in patients with non-small cell lung cancer treated with PD1 inhibitors: a prospective study. Journal For Immunotherapy of Cancer. 8. PMID 32709713 DOI: 10.1136/Jitc-2020-000645 |
0.308 |
|
2020 |
Srikanthan MA, Humbert O, Haworth KG, Ironside C, Rajawat YS, Blazar BR, Palchaudhuri R, Boitano AE, Cooke MP, Scadden DT, Kiem HP. Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning. Molecular Therapy. Methods & Clinical Development. 17: 455-464. PMID 32226796 DOI: 10.1016/J.Omtm.2020.02.001 |
0.31 |
|
2020 |
Vincent L, Jankowski C, Arnould L, Coudert B, Rouzier R, Reyal F, Humbert O, Coutant C. Performances prédictives du TEP-TDM et du nomogramme CGFL/Curie après chimiothérapie néoadjuvante du Cancer du sein GynéCologie ObstéTrique Fertilité & SéNologie. 48: 679-686. PMID 32205278 DOI: 10.1016/J.Gofs.2020.03.015 |
0.329 |
|
2020 |
Radtke S, Humbert O, Kiem H. Mouse models in hematopoietic stem cell gene therapy and genome editing. Biochemical Pharmacology. 174: 113692. PMID 31705854 DOI: 10.1016/J.Bcp.2019.113692 |
0.321 |
|
2020 |
Vincent L, Jankowski C, Cortet M, Arnould L, Ladoire S, Coudert B, Desmoulins I, Charron-Barra C, Beltjens F, Rouzier R, Reyal F, Humbert O, Cochet A, Coutant C. Abstract P2-16-14: HER2-positive breast cancer: Combined18F-FDG PET and CGFL/Curie nomogram to predict pathologic complete response after preoperative chemotherapy with trastuzumab Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P2-16-14 |
0.316 |
|
2020 |
Chateau Y, Schiappa R, Humbert O, Chauviere D, Jacquinot F, Patriti S, Baudin G, Chamorey E. Création d’un outil électronique d’évaluation de la réponse thérapeutique par l’imagerie en oncologie : le projet EVA® Revue D Epidemiologie Et De Sante Publique. 68. DOI: 10.1016/J.Respe.2020.03.044 |
0.317 |
|
2020 |
Chardin D, Pourcher T, Gal J, Bailleux C, Guigonis JM, Darcourt J, Arnould L, Humbert O. Métabolomique et imagerie TEP-FDG des cancers du sein Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. DOI: 10.1016/J.Mednuc.2020.03.002 |
0.355 |
|
2020 |
Chardin D, Paquet M, Darcourt J, Zwarthoed C, Schiazza A, Ouvrier MJ, Benisvy D, Otto J, Humbert O. Valeur pronostique du volume métabolique total chez les patients traités par immunothérapie pour un cancer bronchopulmonaire non à petites cellules Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 44: 124. DOI: 10.1016/J.Mednuc.2020.01.056 |
0.338 |
|
2019 |
Rajawat YS, Humbert O, Kiem H. In-Vivo Gene Therapy with Foamy Virus Vectors. Viruses. 11: 1091. PMID 31771194 DOI: 10.3390/V11121091 |
0.303 |
|
2019 |
Humbert O, Radtke S, Samuelson C, Carrillo RR, Perez AM, Reddy SS, Lux C, Pattabhi S, Schefter LE, Negre O, Lee CM, Bao G, Adair JE, Peterson CW, Rawlings DJ, et al. Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates. Science Translational Medicine. 11. PMID 31366580 DOI: 10.1126/Scitranslmed.Aaw3768 |
0.327 |
|
2019 |
Shahbazi R, Sghia-Hughes G, Reid JL, Kubek S, Haworth KG, Humbert O, Kiem HP, Adair JE. Targeted homology-directed repair in blood stem and progenitor cells with CRISPR nanoformulations. Nature Materials. PMID 31133730 DOI: 10.1038/S41563-019-0385-5 |
0.314 |
|
2019 |
Radtke S, Perez AM, Venkataraman R, Reddy S, Haworth KG, Humbert O, Kiem HP, Peterson CW. Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells. Journal of Visualized Experiments : Jove. PMID 30829324 DOI: 10.3791/58933 |
0.35 |
|
2019 |
Lux CT, Pattabhi S, Berger M, Nourigat C, Flowers DA, Negre O, Humbert O, Yang JG, Lee C, Jacoby K, Bernstein I, Kiem HP, Scharenberg A, Rawlings DJ. TALEN-Mediated Gene Editing of in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction. Molecular Therapy. Methods & Clinical Development. 12: 175-183. PMID 30705922 DOI: 10.1016/J.Omtm.2018.12.008 |
0.333 |
|
2019 |
Humbert O, Riedinger J, Chardin D, Desmoulins I, Brunotte F, Cochet A. SUV calculation in breast cancer: which normalization should be applied when using 18F-FDG PET? Quarterly Journal of Nuclear Medicine and Molecular Imaging. 63: 399. PMID 29345443 DOI: 10.23736/S1824-4785.18.03006-6 |
0.344 |
|
2019 |
Vincent L, Jankowski C, Cortet M, Arnould L, Ladoire S, Coudert BP, Desmoulins I, Charon-Barra C, Beltjens F, Rouzier R, Reyal F, Humbert O, Cochet A, Coutant C. HER2-positive breast cancer: Combined 18F-FDG PET and CGFL/Curie nomogram to predict pathologic complete response after preoperative chemotherapy with trastuzumab. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E12095 |
0.324 |
|
2019 |
Gal J, Bailleux C, Chardin D, Pourcher T, Schiappa R, Gilhodes J, Humbert O, Chamorey E. Comparaison de différentes méthodes d’apprentissage non-supervisées dans le cas de données de grandes dimensions. Application dans le cancer du sein Revue D Epidemiologie Et De Sante Publique. 67. DOI: 10.1016/J.Respe.2019.03.102 |
0.322 |
|
2018 |
Depardon E, Kanoun S, Humbert O, Bertaut A, Riedinger JM, Tal I, Vrigneaud JM, Lasserre M, Toubeau M, Berriolo-Riedinger A, Dygai-Cochet I, Fumoleau P, Brunotte F, Cochet A. FDG PET/CT for prognostic stratification of patients with metastatic breast cancer treated with first line systemic therapy: Comparison of EORTC criteria and PERCIST. Plos One. 13: e0199529. PMID 30011328 DOI: 10.1371/Journal.Pone.0199529 |
0.334 |
|
2018 |
Humbert O, Chan F, Rajawat YS, Torgerson TR, Burtner CR, Hubbard NW, Humphrys D, Norgaard ZK, O'Donnell P, Adair JE, Trobridge GD, Scharenberg AM, Felsburg PJ, Rawlings DJ, Kiem HP. Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy. Blood Advances. 2: 987-999. PMID 29720491 DOI: 10.1182/Bloodadvances.2018016451 |
0.324 |
|
2018 |
Humbert O, Lasserre M, Bertaut A, Fumoleau P, Coutant C, Brunotte F, Cochet A. Breast Cancer Blood Flow and Metabolism on Dual-Acquisition F-FDG PET: Correlation with Tumor Phenotype and Neoadjuvant Chemotherapy Response. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 59: 1035-1041. PMID 29439010 DOI: 10.2967/Jnumed.117.203075 |
0.342 |
|
2018 |
Humbert O, Peterson CW, Norgaard ZK, Radtke S, Kiem HP. A Nonhuman Primate Transplantation Model to Evaluate Hematopoietic Stem Cell Gene Editing Strategies for β-Hemoglobinopathies. Molecular Therapy. Methods & Clinical Development. 8: 75-86. PMID 29276718 DOI: 10.1016/J.Omtm.2017.11.005 |
0.333 |
|
2018 |
Walter RB, Humbert O, Laszlo GS, Sichel SR, Ironside CM, Haworth KG, Bates OM, Beddoe ME, Carillo RR, Kiem H. Engineering Resistance to CD33-Targeted Immunotherapy in Normal Hematopoiesis By CRISPR/Cas9-Deletion of CD33 Exon 2 Blood. 132: 2200-2200. DOI: 10.1182/Blood-2018-99-117856 |
0.3 |
|
2018 |
Humbert O, Radtke S, Carillo RR, Perez AM, Reddy SS, Schefter LE, Lux C, Pattabhi S, Negre O, Lee CM, Adair J, Peterson C, Bao G, Rawlings DJ, Scharenberg AM, et al. Persistence of CRISPR/Cas9-Edited Hematopoietic Stem and Progenitor Cells and Reactivation of Fetal Hemoglobin in Nonhuman Primates Blood. 132: 806-806. DOI: 10.1182/Blood-2018-99-112996 |
0.359 |
|
2018 |
Gal J, Barlaud M, Pourcher T, Bailleux C, Jing L, Chamorey E, Humbert O. Étude des marqueurs métaboliques du cancer du sein adjuvant : comparaison de différentes méthodes de clustering Revue D Epidemiologie Et De Sante Publique. 66. DOI: 10.1016/J.Respe.2018.03.308 |
0.33 |
|
2018 |
Orlhac F, Humbert O, Pourcher T, Jing L, Guigonis J, Darcourt J, Ayache N, Bouveyron C. Analyse statistique de données radiomiques et métabolomiques : prédiction des lésions mammaires triple-négatives Revue D Epidemiologie Et De Sante Publique. 66. DOI: 10.1016/J.Respe.2018.03.307 |
0.326 |
|
2018 |
Orlhac F, Humbert O, Boughdad S, Lasserre M, Soussan M, Nioche C, Ayache N, Darcourt J, Frouin F, Buvat I. Validation d'une méthode d'harmonisation des mesures SUV et des variables radiomiques pour les études TEP multicentriques rétrospectives Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 42: 170. DOI: 10.1016/J.Mednuc.2018.03.097 |
0.31 |
|
2018 |
Orlhac F, Bouveyron C, Pourcher T, Jing L, Guigonis J, Darcourt J, Ayache N, Humbert O. Identification des cancers mammaires triple-négatifs : analyse statistique de variables radiomiques issues des images TEP et de variables métabolomiques Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 42: 169. DOI: 10.1016/J.Mednuc.2018.03.096 |
0.331 |
|
2018 |
Cadour N, Koulibaly PM, Humbert O, Schiazza A, Benisvy D, Paquet M, Ouvrier MJ, Hayden C, Darcourt J, Zwarthoed C. Un nouveau protocole d’acquisition TEP/TDM statique et dynamique simultanée Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 42: 155-156. DOI: 10.1016/J.Mednuc.2018.03.057 |
0.331 |
|
2018 |
Cadour N, Benisvy D, Borchiellini D, Ouvrier MJ, Swarthoed C, Schiazza A, Paquet M, Darcourt J, Humbert O. Valeur de la TEP au 18FDG intérimaire pour prédire précocement la réponse à l’immunothérapie du cancer bronchopulmonaire Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 42: 147. DOI: 10.1016/J.Mednuc.2018.03.038 |
0.334 |
|
2018 |
Lasserre M, Humbert O, Bertaud A, Fumoleau P, Coutant C, Brunotte F, Cochet A. Pattern of breast cancer blood flow and metabolism, assessed using dual-acquisition 18FDG PET: Correlation with tumor phenotypic features and pathological response to neoadjuvant chemotherapy Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 42: 133. DOI: 10.1016/J.Mednuc.2018.03.006 |
0.336 |
|
2017 |
Chardin D, Humbert O, Bourg V, Peyrade F, Benisvy D, Zwarthoed C, Schiazza A, Ouvrier MJ, Darcourt J. Quand la médecine nucléaire trouve la racine du mal Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 41: 190-191. DOI: 10.1016/J.Mednuc.2017.02.141 |
0.321 |
|
2016 |
Groheux D, Cochet A, Humbert O, Alberini J, Hindié E, Mankoff D. ¹⁸F-FDG PET/CT for Staging and Restaging of Breast Cancer. The Journal of Nuclear Medicine. 57. PMID 26834096 DOI: 10.2967/Jnumed.115.157859 |
0.316 |
|
2016 |
Chan F, Humbert O, Torgerson T, Hubbard N, O'Donnell P, Humphrys DR, Adair JE, Felsburg P, Trobridge GD, Scharenberg AM, Rawlings DJ, Kiem H. Rapid Expansion of Gene-Marked Lymphocytes in X-SCID Dogs after AMD3100+G-CSF-Based Hematopoietic Stem/Progenitor Cell Mobilization and Intravenous Injection of a Common γ-Chain Expressing Foamy Viral Vector Blood. 128: 1348-1348. DOI: 10.1182/Blood.V128.22.1348.1348 |
0.352 |
|
2016 |
Humbert O, Gisch DW, Wohlfahrt ME, Adams AB, Greenberg PD, Schmitt TM, Trobridge GD, Kiem HP. Development of third-generation cocal envelope producer cell lines for robust lentiviral gene transfer into hematopoietic stem cells and t-cells Molecular Therapy. 24: 1237-1246. DOI: 10.1038/Mt.2016.70 |
0.326 |
|
2016 |
Humbert O, Kiem H. 758. A Nonhuman Primate Transplantation Model to Evaluate Gene Editing Strategies Aimed at Inducing Fetal Hemoglobin Production for the Treatment of Hemoglobinopathies Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33566-3 |
0.33 |
|
2016 |
Humbert O, Gisch D, Wohlfahrt M, Greenberg P, Schmitt T, Trobridge G, Kiem H. 288. Development of Cocal Glycoprotein Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T Cells Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33097-0 |
0.331 |
|
2016 |
Chan F, Humbert O, Burtner C, Humphrys D, Adair J, Trobridge G, O'Donnell P, Hubbard N, Torgerson T, Scharenberg A, Rawlings D, Felsburg PJ, Kiem H. 284. Long-Term Therapeutic Immune Reconstitution in XSCID Canine Model via In Vivo Foamy Virus Delivery of Common Gamma Chain Molecular Therapy. 24: S114. DOI: 10.1016/S1525-0016(16)33093-3 |
0.322 |
|
2016 |
Boudaoud AA, Verges B, Petit JM, Humbert O, Cochet A. Fixation de l’uncus pancréatique à l’octréoscan : comment distinguer le physiologique du pathologique ? Annales D Endocrinologie. 77: 298-299. DOI: 10.1016/J.Ando.2016.07.158 |
0.327 |
|
2015 |
Humbert O, Burtner CR, O'Donnell P, Humphrys DR, Hubbard N, Chan F, Adair JE, Trobridge GD, Torgerson T, Scharenberg AM, Rawlings DJ, Felsburg P, Kiem H. Pgk-Mediated Expression of Common Gamma Chain Is More Effective Than EF1a for Therapeutic Immune Reconstitution of X-SCID Dogs after In Vivo Gene Therapy with Foamy Virus Vector Blood. 126: 262-262. DOI: 10.1182/Blood.V126.23.262.262 |
0.346 |
|
2015 |
Humbert O, Kiem H. Long-Term Increase in Fetal Hemoglobin Expression in Nonhuman Primates Following Transplantation of Autologous Bcl11a Nuclease-Edited HSCs Blood. 126: 2035-2035. DOI: 10.1182/Blood.V126.23.2035.2035 |
0.324 |
|
2015 |
Humbert OM, Adams AB, Gish DW, Wohlfahrt ME, Adair JE, Trobridge GD, Kiem H. 528. Generation of a Cocal Envelope Packaging Cell Line for Robust Lentiviral Gene Transfer Into Hematopoietic Stem Cells and T Cells Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34137-5 |
0.329 |
|
2015 |
Depardon E, Kanoun S, Humbert O, Lasserre M, Toubeau M, Berriolo-Riedinger A, Dygai-Cochet I, Fumoleau P, Brunotte F, Cochet A. Valeur pronostique de la réponse métabolique en TEP-FDG des cancers du sein métastatiques après une première ligne de traitement systémique Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 39: 257-257. DOI: 10.1016/J.Mednuc.2015.03.177 |
0.353 |
|
2015 |
Humbert O, Riedinger JM, Charon-Barra C, Berriolo-Riedinger A, Desmoulins I, Cochet I, Depardon E, Fumoleau P, Brunotte F. Identification de biomarqueurs prédictifs de la réponse des cancers du sein triple-négatifs : intérêt de la TEP/TDM au 18FDG Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 39: 215-216. DOI: 10.1016/J.Mednuc.2015.03.032 |
0.354 |
|
2014 |
Rossi C, Kanoun S, Berriolo-Riedinger A, Dygai-Cochet I, Humbert O, Legouge C, Chrétien ML, Bastie J, Brunotte F, Casasnovas R. Interim 18F-FDG PET SUVmax Reduction Is Superior to Visual Analysis in Predicting Outcome Early in Hodgkin Lymphoma Patients The Journal of Nuclear Medicine. 55: 569-573. PMID 24566003 DOI: 10.2967/Jnumed.113.130609 |
0.328 |
|
2014 |
Burtner CR, Humbert O, O'Donnell P, Hubbard N, Humphrys D, Adair JE, Trobridge GD, Torgerson TR, Scharenberg AM, Rawlings D, Felsburg PJ, Kiem H. Robust Therapeutic Expression of the Common Gamma Chain with the Human Pgk Promoter Using Foamy Virus in Vivo Gene Therapy in a Canine Model of Severe Combined Immunodeficiency Blood. 124: 4794-4794. DOI: 10.1182/Blood.V124.21.4794.4794 |
0.354 |
|
2014 |
Kanoun S, Walker P, Créhange G, Humbert O, Berriolo-Riedinger A, Dygai-Cochet I, Toubeau M, Depardon E, Brunotte F, Cochet A. Analyse quantitative de la prostate en TEP/TDM à la 18F-Fluorocholine guidée par l’IRM multimodale lors de la récidive biochimique du cancer prostatique Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 38: 130. DOI: 10.1016/J.Mednuc.2014.03.015 |
0.301 |
|
2013 |
Humbert O, Berriolo-Riedinger A, Cochet A, Gauthier M, Charon-Barra C, Desmoulins I, Guiu S, Toubeau M, Dygai-Cochet I, Coutant C, Fumoleau P, Brunotte F. Prognostic relevance at 5 years of the early monitoring of neoadjuvant chemotherapy using FDG PET in luminal HER2-negative breast cancer. Journal of Clinical Oncology. 31: 11007-11007. DOI: 10.1200/Jco.2013.31.15_Suppl.11007 |
0.315 |
|
2012 |
Humbert O, Berriolo-Riedinger A, Riedinger J, Coudert B, Arnould L, Cochet A, Loustalot C, Fumoleau P, Brunotte F. Changes in 18F-FDG tumor metabolism after a first course of neoadjuvant chemotherapy in breast cancer: influence of tumor subtypes Annals of Oncology. 23: 2572-2577. PMID 22499859 DOI: 10.1093/Annonc/Mds071 |
0.322 |
|
2012 |
Kanoun S, Rossi C, Berriolo-Riedinger A, Humbert O, Dygay-Cochet I, Chretien M, Legouge C, Berthet L, Bastie J, Casasnovas R. Metabolic Tumor Volume Is an Independent Prognosis Factor Predicting patient's Outcome in Hodgkin Lymphoma Blood. 120: 3631-3631. DOI: 10.1182/Blood.V120.21.3631.3631 |
0.341 |
|
2012 |
Rossi C, Kanoun S, Berriolo-Riedinger A, Humbert O, Dygay-Cochet I, Legouge C, Chretien M, Berthet L, Bastie J, Casasnovas R. Interim [18F]Fluorodeoxyglucosepositron Emission Tomography Suvmax Reduction Is Superior to Visual Analysis to Predict Early patient's Outcome in Hodgkin Lymphoma Blood. 120: 3630-3630. DOI: 10.1182/Blood.V120.21.3630.3630 |
0.338 |
|
2011 |
Humbert O, Dorer MS, Salama NR. Characterization of Helicobacter pylori factors that control transformation frequency and integration length during inter-strain DNA recombination. Molecular Microbiology. 79: 387-401. PMID 21219459 DOI: 10.1111/J.1365-2958.2010.07456.X |
0.507 |
|
2011 |
Humbert O, Dygai-Cochet I, Gauthier M, Cochet A, Berriolo-Riedinger A, Crehange G, Toubeau M, Brunotte F. Valeur pronostique de la TEP au 18F-FDG dans le bilan d’extension initial du cancer de l’œsophage traité par radiochimiothérapie exclusive Medecine Nucleaire-Imagerie Fonctionnelle Et Metabolique. 35: 186-194. DOI: 10.1016/J.Mednuc.2011.02.010 |
0.353 |
|
2010 |
Cochet A, Pigeonnat S, Buvry B, Berriolo-Riedinger A, Humbert O, Coudert B, Fumoleau P, Arnould L, Brunotte F. Abstract P5-01-09: Evaluation of Tumor Blood Flow with Dynamic18F-Fluorodeoxyglucose Positron Emission Tomography: Correlation with Microvessel Density Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P5-01-09 |
0.352 |
|
2010 |
Berriolo-Riedinger A, Humbert O, Riedinger J, Arnoud L, Coudert B, Dygai-Cochet I, Cochet A, Toubeau M, Fumoleau P, Brunotte F. Abstract P5-01-06: 18[F]-FDG Tumoral Uptake and Metabolic Response after 1 Cycle of Primary Chemotherapy According to Tumoral Phenotype of Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P5-01-06 |
0.351 |
|
2010 |
Humbert O, Berriolo-Riedinger A, Arnoud L, Coudert B, Toubeau M, Dygai-Cochet I, Cochet A, Mayer F, Fumoleau P, Brunotte F. Abstract P5-01-05: Prognostic Value at 4 Years of FDG PET, after the First Course of Neoadjuvant Chemotherapy in Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P5-01-05 |
0.351 |
|
2008 |
Humbert O, Salama NR. The Helicobacter pylori HpyAXII restriction-modification system limits exogenous DNA uptake by targeting GTAC sites but shows asymmetric conservation of the DNA methyltransferase and restriction endonuclease components. Nucleic Acids Research. 36: 6893-906. PMID 18978016 DOI: 10.1093/Nar/Gkn718 |
0.509 |
|
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