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Frederick S. Gimble - Publications

Affiliations: 
Biochemistry Purdue University, West Lafayette, IN, United States 
Area:
Biochemistry, General Biophysics
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Nawimanage R, Yuan Z, Casares M, Joshi R, Lohman JR, Gimble FS. Structure-function studies of two yeast homing endonucleases that evolved to cleave identical targets with dissimilar rates and specificities. Journal of Molecular Biology. 167550. PMID 35317996 DOI: 10.1016/j.jmb.2022.167550  0.645
2021 Lee KZ, Mechikoff MA, Kikla A, Liu A, Pandolfi P, Fitzgerald K, Gimble FS, Solomon KV. NgAgo possesses guided DNA nicking activity. Nucleic Acids Research. PMID 34478558 DOI: 10.1093/nar/gkab757  0.493
2014 Katz SS, Gimble FS, Storici F. To nick or not to nick: comparison of I-SceI single- and double-strand break-induced recombination in yeast and human cells. Plos One. 9: e88840. PMID 24558436 DOI: 10.1371/Journal.Pone.0088840  0.499
2014 Joshi R, Gimble FS. A bacterial one-hybrid system to isolate homing endonuclease variants with altered DNA target specificities. Methods in Molecular Biology (Clifton, N.J.). 1114: 221-36. PMID 24557906 DOI: 10.1007/978-1-62703-761-7_14  0.611
2011 Joshi R, Ho KK, Tenney K, Chen JH, Golden BL, Gimble FS. Evolution of I-SceI homing endonucleases with increased DNA recognition site specificity. Journal of Molecular Biology. 405: 185-200. PMID 21029741 DOI: 10.1016/J.Jmb.2010.10.029  0.631
2008 Niu Y, Tenney K, Li H, Gimble FS. Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity. Journal of Molecular Biology. 382: 188-202. PMID 18644379 DOI: 10.1016/J.Jmb.2008.07.010  0.576
2008 Moure CM, Gimble FS, Quiocho FA. Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway. Nucleic Acids Research. 36: 3287-96. PMID 18424798 DOI: 10.1093/Nar/Gkn178  0.517
2007 Gimble FS. Engineering homing endonucleases to modify complex genomes Gene Therapy and Regulation. 3: 33-50. DOI: 10.1142/S1568558607000034  0.508
2006 Gimble FS. Broken symmetry in homing endonucleases. Structure (London, England : 1993). 14: 804-6. PMID 16698541 DOI: 10.1016/J.Str.2006.05.001  0.444
2004 Posey KL, Koufopanou V, Burt A, Gimble FS. Evolution of divergent DNA recognition specificities in VDE homing endonucleases from two yeast species. Nucleic Acids Research. 32: 3947-56. PMID 15280510 DOI: 10.1093/Nar/Gkh734  0.524
2003 Gimble FS, Moure CM, Posey KL. Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system. Journal of Molecular Biology. 334: 993-1008. PMID 14643662 DOI: 10.1016/J.Jmb.2003.10.013  0.611
2003 Moure CM, Gimble FS, Quiocho FA. The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity. Journal of Molecular Biology. 334: 685-95. PMID 14636596 DOI: 10.1016/J.Jmb.2003.09.068  0.572
2002 Moure CM, Gimble FS, Quiocho FA. Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence. Nature Structural Biology. 9: 764-70. PMID 12219083 DOI: 10.1038/Nsb840  0.545
2002 Posey KL, Gimble FS. Insertion of a reversible redox switch into a rare-cutting DNA endonuclease. Biochemistry. 41: 2184-90. PMID 11841209 DOI: 10.1021/Bi015944V  0.575
2001 Gimble FS. Degeneration of a homing endonuclease and its target sequence in a wild yeast strain Nucleic Acids Research. 29: 4215-4223. PMID 11600710 DOI: 10.1093/Nar/29.20.4215  0.504
2000 Gimble FS. Invasion of a multitude of genetic niches by mobile endonuclease genes Fems Microbiology Letters. 185: 99-107. PMID 10754232 DOI: 10.1111/J.1574-6968.2000.Tb09046.X  0.389
2000 Hu D, Crist M, Duan X, Quiocho FA, Gimble FS. Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking. The Journal of Biological Chemistry. 275: 2705-12. PMID 10644733 DOI: 10.1074/Jbc.275.4.2705  0.585
1999 Hu D, Crist M, Duan X, Gimble FS. Mapping of a DNA binding region of the PI-SceI homing endonuclease by affinity cleavage and alanine-scanning mutagenesis Biochemistry. 38: 12621-12628. PMID 10504231 DOI: 10.1021/Bi991192H  0.556
1998 Gimble FS. Putting protein splicing to work Chemistry and Biology. 5. PMID 9818144 DOI: 10.1016/S1074-5521(98)90109-0  0.309
1998 Gimble FS, Duan X, Hu D, Quiocho FA. Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center. The Journal of Biological Chemistry. 273: 30524-9. PMID 9804821 DOI: 10.1074/Jbc.273.46.30524  0.547
1998 He Z, Crist M, Yen H, Duan X, Quiocho FA, Gimble FS. Amino acid residues in both the protein splicing and endonuclease domains of the PI-SceI intein mediate DNA binding. The Journal of Biological Chemistry. 273: 4607-15. PMID 9468518 DOI: 10.1074/Jbc.273.8.4607  0.503
1997 Duan X, Gimble FS, Quiocho FA. Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity. Cell. 89: 555-64. PMID 9160747 DOI: 10.1016/S0092-8674(00)80237-8  0.479
1996 Gimble FS, Wang J. Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing Journal of Molecular Biology. 263: 163-180. PMID 8913299 DOI: 10.1006/Jmbi.1996.0567  0.58
1996 Brenneman M, Gimble FS, Wilson JH. Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases Proceedings of the National Academy of Sciences of the United States of America. 93: 3608-3612. PMID 8622983 DOI: 10.1073/Pnas.93.8.3608  0.451
1995 Gimble FS, Stephens BW. Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease Journal of Biological Chemistry. 270: 5849-5856. PMID 7890714 DOI: 10.1074/Jbc.270.11.5849  0.556
1993 Gimble FS, Thorner J. Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 268: 21844-53. PMID 8408039  0.356
1992 Gimble FS, Thorner J. Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature. 357: 301-6. PMID 1534148 DOI: 10.1038/357301A0  0.454
1992 Bremer MC, Gimble FS, Thorner J, Smith CL. VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene. Nucleic Acids Research. 20: 5484. PMID 1437572 DOI: 10.1093/Nar/20.20.5484  0.432
1989 Gimble FS, Sauer RT. λ Repressor mutants that are better substrates for RecA-mediated cleavage Journal of Molecular Biology. 206: 29-39. PMID 2522996 DOI: 10.1016/0022-2836(89)90521-4  0.416
1986 Gimble FS, Sauer RT. λ Repressor inactivation: Properties of purified ind- proteins in the autodigestion and RecA-mediated cleavage reactions Journal of Molecular Biology. 192: 39-47. PMID 3820305 DOI: 10.1016/0022-2836(86)90462-6  0.412
1985 Gimble FS, Sauer RT. Mutations in bacteriophage λ repressor that prevent recA-mediated cleavage Journal of Bacteriology. 162: 147-154. PMID 3156848 DOI: 10.1128/Jb.162.1.147-154.1985  0.384
1983 Sauer RT, Nelson HC, Hehir K, Hecht MH, Gimble FS, DeAnda J, Poteete AR. The lambda and P22 phage repressors. Journal of Biomolecular Structure & Dynamics. 1: 1011-22. PMID 6242868 DOI: 10.1080/07391102.1983.10507499  0.348
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