| Year |
Citation |
Score |
| 2024 |
Porras C, Olliviere H, Bradley SP, Graham AM, Chudasama Y, Rouault TA. Ablation of Iron Regulatory Protein 2 produces a neurological disorder characterized by motor, somatosensory, and executive dysfunction in mice. Current Research in Neurobiology. 7: 100136. PMID 39239479 DOI: 10.1016/j.crneur.2024.100136 |
0.412 |
|
| 2024 |
Maio N, Orbach R, Zaharieva IT, Töpf A, Donkervoort S, Munot P, Mueller J, Willis T, Verma S, Peric S, Krishnakumar D, Sudhakar S, Foley AR, Silverstein S, Douglas G, ... ... Rouault TA, et al. CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymes. The Journal of Clinical Investigation. 134. PMID 38950322 DOI: 10.1172/JCI179559 |
0.432 |
|
| 2024 |
Zhang DL, Ollivierre H, Rouault TA. Using Biotinylated Iron-Responsive Element to Analyze the Activity of Iron Regulatory Proteins. International Journal of Molecular Sciences. 25. PMID 38732071 DOI: 10.3390/ijms25094852 |
0.485 |
|
| 2023 |
Maio N, Orbach R, Zaharieva I, Töpf A, Donkervoort S, Munot P, Mueller J, Willis T, Verma S, Peric S, Krishnakumar D, Sudhakar S, Foley AR, Silverstein S, Douglas G, ... ... Rouault T, et al. Loss of Function of the Cytoplasmic Fe-S Assembly Protein CIAO1 Causes a Neuromuscular Disorder with Compromise of Nucleocytoplasmic Fe-S Enzymes. Medrxiv : the Preprint Server For Health Sciences. PMID 38196629 DOI: 10.1101/2023.12.20.23300170 |
0.496 |
|
| 2023 |
Maio N, Raza MK, Li Y, Zhang DL, Bollinger JM, Krebs C, Rouault TA. An iron-sulfur cluster in the zinc-binding domain of the SARS-CoV-2 helicase modulates its RNA-binding and -unwinding activities. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303860120. PMID 37552760 DOI: 10.1073/pnas.2303860120 |
0.427 |
|
| 2022 |
Maio N, Saneto RP, Steet R, Sotero de Menezes MA, Skinner C, Rouault TA. Disruption of cellular iron homeostasis by missense variants causes severe neurodevelopmental delay, dystonia and seizures. Brain Communications. 4: fcac102. PMID 35602653 DOI: 10.1093/braincomms/fcac102 |
0.547 |
|
| 2022 |
Porras CA, Rouault TA. Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption. International Journal of Molecular Sciences. 23. PMID 35562883 DOI: 10.3390/ijms23094490 |
0.512 |
|
| 2022 |
Maio N, Rouault TA. Mammalian iron sulfur cluster biogenesis and human diseases. Iubmb Life. PMID 35098635 DOI: 10.1002/iub.2597 |
0.452 |
|
| 2022 |
Maio N, Rouault TA. Mammalian iron sulfur cluster biogenesis: From assembly to delivery to recipient proteins with a focus on novel targets of the chaperone and co-chaperone proteins. Iubmb Life. PMID 35080107 DOI: 10.1002/iub.2593 |
0.399 |
|
| 2021 |
Yook JS, You M, Kim J, Toney AM, Fan R, Puniya BL, Helikar T, Vaulont S, Deschemin JC, Okla M, Xie L, Ghosh MC, Rouault TA, Lee J, Chung S. Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34593646 DOI: 10.1073/pnas.2109186118 |
0.523 |
|
| 2021 |
Maio N, Zhang DL, Ghosh MC, Jain A, SantaMaria AM, Rouault TA. Mechanisms of cellular iron sensing, regulation of erythropoiesis and mitochondrial iron utilization. Seminars in Hematology. 58: 161-174. PMID 34389108 DOI: 10.1053/j.seminhematol.2021.06.001 |
0.568 |
|
| 2021 |
Maio N, Lafont BAP, Sil D, Li Y, Bollinger JM, Krebs C, Pierson TC, Linehan WM, Rouault TA. Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets. Science (New York, N.Y.). PMID 34083449 DOI: 10.1126/science.abi5224 |
0.321 |
|
| 2021 |
Crooks DR, Maio N, Lang M, Ricketts CJ, Vocke CD, Gurram S, Turan S, Kim YY, Cawthon GM, Sohelian F, De Val N, Pfeiffer RM, Jailwala P, Tandon M, Tran B, ... ... Rouault TA, et al. Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer. Science Signaling. 14. PMID 33402335 DOI: 10.1126/scisignal.abc4436 |
0.597 |
|
| 2020 |
Liu G, Sil D, Maio N, Tong WH, Bollinger JM, Krebs C, Rouault TA. Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase. Nature Communications. 11: 6310. PMID 33298951 DOI: 10.1038/s41467-020-20145-9 |
0.495 |
|
| 2020 |
Jain A, Singh A, Maio N, Rouault TA. Assembly of the [4Fe-4S] cluster of NFU1 requires the coordinated donation of two [2Fe-2S] clusters from the scaffold proteins, ISCU2 and ISCA1. Human Molecular Genetics. PMID 32776106 DOI: 10.1093/Hmg/Ddaa172 |
0.474 |
|
| 2020 |
Maio N, Rouault TA. Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis. Trends in Biochemical Sciences. 45: 411-426. PMID 32311335 DOI: 10.1016/J.Tibs.2020.02.001 |
0.498 |
|
| 2020 |
Rouault TA, Maio N. How Oxidation of a Unique Iron-Sulfur Cluster in FBXL5 Regulates IRP2 Levels and Promotes Regulation of Iron Metabolism Proteins. Molecular Cell. 78: 1-3. PMID 32243827 DOI: 10.1016/J.Molcel.2020.03.020 |
0.585 |
|
| 2020 |
Palmieri EM, Gonzalez-Cotto M, Baseler WA, Davies LC, Ghesquière B, Maio N, Rice CM, Rouault TA, Cassel T, Higashi RM, Lane AN, Fan TW, Wink DA, McVicar DW. Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase. Nature Communications. 11: 698. PMID 32019928 DOI: 10.1038/S41467-020-14433-7 |
0.308 |
|
| 2020 |
Maio N, Jain A, Rouault TA. Mammalian iron-sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins. Current Opinion in Chemical Biology. 55: 34-44. PMID 31918395 DOI: 10.1016/J.Cbpa.2019.11.014 |
0.5 |
|
| 2019 |
Lee NJ, Ha SK, Sati P, Absinta M, Nair G, Luciano NJ, Leibovitch EC, Yen CC, Rouault TA, Silva AC, Jacobson S, Reich DS. Potential role of iron in repair of inflammatory demyelinating lesions. The Journal of Clinical Investigation. PMID 31498148 DOI: 10.1172/Jci126809 |
0.513 |
|
| 2019 |
Aerbajinai W, Ghosh MC, Liu J, Kumkhaek C, Zhu J, Chin K, Rouault TA, Rodgers GP. Glia maturation factor-γ regulates murine macrophage iron metabolism and M2 polarization through mitochondrial ROS. Blood Advances. 3: 1211-1225. PMID 30971398 DOI: 10.1182/Bloodadvances.2018026070 |
0.555 |
|
| 2019 |
Rouault TA. The indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 30923992 DOI: 10.1007/S10534-019-00191-7 |
0.512 |
|
| 2019 |
Costain G, Ghosh MC, Maio N, Carnevale A, Si YC, Rouault TA, Yoon G. Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome. Brain : a Journal of Neurology. PMID 30915432 DOI: 10.1093/Brain/Awz072 |
0.629 |
|
| 2019 |
Maio N, Kim KS, Holmes-Hampton G, Singh A, Rouault TA. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. PMID 30765471 DOI: 10.3324/Haematol.2018.214320 |
0.607 |
|
| 2019 |
Rouault T. Ferroportin in Erythrocytes: Importance for Iron Homeostasis and its Role in Infection Blood. 134: SCI-27-SCI-27. DOI: 10.1182/Blood-2019-121071 |
0.609 |
|
| 2018 |
Kim KS, Zhang DL, Kovtunovych G, Ghosh MC, Ollivierre H, Eckhaus MA, Rouault TA. Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of -deficient mice. Blood Advances. 2: 2732-2743. PMID 30337301 DOI: 10.1182/Bloodadvances.2018019737 |
0.465 |
|
| 2018 |
Weiss A, Spektor L, A Cohen L, Lifshitz L, Magid Gold I, Zhang DL, Truman-Rosentsvit M, Leichtmann-Bardoogo Y, Nyska A, Addadi S, Rouault TA, Meyron-Holtz EG. Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention. Plos One. 13: e0204471. PMID 30321179 DOI: 10.1371/Journal.Pone.0204471 |
0.61 |
|
| 2018 |
Zhang DL, Ghosh MC, Ollivierre H, Li Y, Rouault TA. Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress. Blood. PMID 30213870 DOI: 10.1182/Blood-2018-04-842997 |
0.615 |
|
| 2018 |
Tong WH, Maio N, Zhang DL, Palmieri EM, Ollivierre H, Ghosh MC, McVicar DW, Rouault TA. TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation. Blood Advances. 2: 1146-1156. PMID 29784770 DOI: 10.1182/Bloodadvances.2018015669 |
0.495 |
|
| 2018 |
Holmes-Hampton GP, Ghosh MC, Rouault TA. Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism. Methods in Enzymology. 599: 139-155. PMID 29746238 DOI: 10.1016/Bs.Mie.2017.09.006 |
0.648 |
|
| 2018 |
Zhang DL, Wu J, Shah BN, Greutélaers KC, Ghosh MC, Ollivierre H, Su XZ, Thuma PE, Bedu-Addo G, Mockenhaupt FP, Gordeuk VR, Rouault TA. Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk. Science (New York, N.Y.). 359: 1520-1523. PMID 29599243 DOI: 10.1126/Science.Aal2022 |
0.532 |
|
| 2018 |
Crooks DR, Maio N, Lane AN, Jarnik M, Higashi RM, Haller RG, Yang Y, Fan TWM, Linehan M, Rouault TA. Acute loss of iron-sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells. The Journal of Biological Chemistry. PMID 29523684 DOI: 10.1074/Jbc.Ra118.001885 |
0.755 |
|
| 2018 |
Ghosh MC, Zhang DL, Ollivierre H, Eckhaus MA, Rouault TA. Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia. The Journal of Clinical Investigation. PMID 29480820 DOI: 10.1172/Jci97684 |
0.367 |
|
| 2018 |
Zhang DL, Rouault TA. How does hepcidin hinder ferroportin activity? Blood. 131: 840-842. PMID 29472371 DOI: 10.1182/Blood-2018-01-824151 |
0.434 |
|
| 2018 |
Kim KS, Maio N, Singh A, Rouault TA. Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients. Human Molecular Genetics. PMID 29309586 DOI: 10.1093/Hmg/Ddy004 |
0.493 |
|
| 2017 |
Truman-Rosentsvit M, Berenbaum D, Spektor L, Cohen LA, Belizowsky-Moshe S, Lifshitz L, Ma J, Li W, Kesselman E, Abutbul-Ionita I, Danino D, Gutierrez L, Li H, Li K, Lou H, ... ... Rouault TA, et al. Ferritin is secreted via two distinct non-classical vesicular pathways. Blood. PMID 29074498 DOI: 10.1182/Blood-2017-02-768580 |
0.569 |
|
| 2017 |
Rouault TA, Maio N. Biogenesis and Functions of Mammalian Iron-Sulfur Proteins in the Regulation of Iron Homeostasis and Pivotal Metabolic Pathways. The Journal of Biological Chemistry. PMID 28615439 DOI: 10.1074/Jbc.R117.789537 |
0.62 |
|
| 2017 |
Maio N, Kim KS, Singh A, Rouault TA. A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III. Cell Metabolism. 25: 945-953.e6. PMID 28380382 DOI: 10.1016/J.Cmet.2017.03.010 |
0.483 |
|
| 2017 |
Maio N, Rouault TA. Mammalian Fe-S proteins: definition of a consensus motif recognized by the co-chaperone HSC20. Metallomics : Integrated Biometal Science. 8: 1032-1046. PMID 27714045 DOI: 10.1039/C6MT00167J |
0.371 |
|
| 2016 |
Holmes-Hampton GP, Crooks DR, Haller RG, Guo S, Freier SM, Monia BP, Rouault TA. Use of antisense oligonucleotides to correct the splicing error in ISCU myopathy patient cell lines. Human Molecular Genetics. PMID 28007899 DOI: 10.1093/Hmg/Ddw338 |
0.614 |
|
| 2016 |
Rouault TA. Mitochondrial iron overload: causes and consequences. Current Opinion in Genetics & Development. 38: 31-37. PMID 27026139 DOI: 10.1016/J.Gde.2016.02.004 |
0.592 |
|
| 2016 |
Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, ... ... Rouault TA, et al. Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nature Medicine. PMID 26752519 DOI: 10.1038/Nm.4021 |
0.49 |
|
| 2016 |
Maio N, Ghezzi D, Verrigni D, Rizza T, Bertini E, Martinelli D, Zeviani M, Singh A, Carrozzo R, Rouault TA. Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB. Cell Metabolism. 23: 292-302. PMID 26749241 DOI: 10.1016/J.Cmet.2015.12.005 |
0.491 |
|
| 2016 |
Saxena N, Maio N, Crooks DR, Ricketts CJ, Yang Y, Wei MH, Fan TW, Lane AN, Sourbier C, Singh A, Killian JK, Meltzer PS, Vocke CD, Rouault TA, Linehan WM. SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. Journal of the National Cancer Institute. 108. PMID 26719882 DOI: 10.1093/Jnci/Djv287 |
0.721 |
|
| 2016 |
Tong W, Maio N, Rouault TA. Abstract B08: Metabolic adaption in inflammatory macrophages through the modulation of Fe-S cluster biogenesis factors Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B08 |
0.44 |
|
| 2015 |
Saxena N, Maio N, Crooks DR, Ricketts CJ, Yang Y, Wei MH, Fan TW, Lane AN, Sourbier C, Singh A, Killian JK, Meltzer PS, Vocke CD, Rouault TA, Linehan WM. SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. Journal of the National Cancer Institute. 108. PMID 26464466 DOI: 10.1093/jnci/djv287 |
0.709 |
|
| 2015 |
Rouault TA. Iron-sulfur proteins hiding in plain sight. Nature Chemical Biology. 11: 442-5. PMID 26083061 DOI: 10.1038/Nchembio.1843 |
0.569 |
|
| 2015 |
Ghosh MC, Zhang L, Rouault TA. Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins. Neurobiology of Disease. PMID 25771171 DOI: 10.1016/J.Nbd.2015.02.026 |
0.534 |
|
| 2015 |
Rouault TA. Mammalian iron-sulphur proteins: novel insights into biogenesis and function. Nature Reviews. Molecular Cell Biology. 16: 45-55. PMID 25425402 DOI: 10.1038/Nrm3909 |
0.553 |
|
| 2015 |
Maio N, Rouault TA. Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. Biochimica Et Biophysica Acta. 1853: 1493-512. PMID 25245479 DOI: 10.1016/J.Bbamcr.2014.09.009 |
0.564 |
|
| 2014 |
Sourbier C, Ricketts CJ, Matsumoto S, Crooks DR, Liao PJ, Mannes PZ, Yang Y, Wei MH, Srivastava G, Ghosh S, Chen V, Vocke CD, Merino M, Srinivasan R, Krishna MC, ... ... Rouault TA, et al. Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer. Cancer Cell. 26: 840-50. PMID 25490448 DOI: 10.1016/J.Ccell.2014.10.005 |
0.632 |
|
| 2014 |
Holmes-Hampton GP, Tong WH, Rouault TA. Biochemical and biophysical methods for studying mitochondrial iron metabolism. Methods in Enzymology. 547: 275-307. PMID 25416363 DOI: 10.1016/B978-0-12-801415-8.00015-1 |
0.589 |
|
| 2014 |
Zhang DL, Ghosh MC, Rouault TA. The physiological functions of iron regulatory proteins in iron homeostasis - an update. Frontiers in Pharmacology. 5: 124. PMID 24982634 DOI: 10.3389/Fphar.2014.00124 |
0.605 |
|
| 2014 |
Kovtunovych G, Ghosh MC, Ollivierre W, Weitzel RP, Eckhaus MA, Tisdale JF, Yachie A, Rouault TA. Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice. Blood. 124: 1522-30. PMID 24963040 DOI: 10.1182/Blood-2014-02-554162 |
0.395 |
|
| 2014 |
Frey AG, Nandal A, Park JH, Smith PM, Yabe T, Ryu MS, Ghosh MC, Lee J, Rouault TA, Park MH, Philpott CC. Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase. Proceedings of the National Academy of Sciences of the United States of America. 111: 8031-6. PMID 24843120 DOI: 10.1073/Pnas.1402732111 |
0.629 |
|
| 2014 |
Kosmidis S, Missirlis F, Botella JA, Schneuwly S, Rouault TA, Skoulakis EM. Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia. Frontiers in Pharmacology. 5: 66. PMID 24772084 DOI: 10.3389/Fphar.2014.00066 |
0.432 |
|
| 2014 |
Maio N, Singh A, Uhrigshardt H, Saxena N, Tong WH, Rouault TA. Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery. Cell Metabolism. 19: 445-57. PMID 24606901 DOI: 10.1016/J.Cmet.2014.01.015 |
0.476 |
|
| 2014 |
Crooks DR, Natarajan TG, Jeong SY, Chen C, Park SY, Huang H, Ghosh MC, Tong WH, Haller RG, Wu C, Rouault TA. Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle. Human Molecular Genetics. 23: 24-39. PMID 23943793 DOI: 10.1093/Hmg/Ddt393 |
0.719 |
|
| 2014 |
Rouault TA. Biogenesis of Fe-S proteins in mammals Iron-Sulfur Clusters in Chemistry and Biology. 437-454. DOI: 10.1515/9783110308426.437 |
0.318 |
|
| 2014 |
Bonomi F, Rouault TA. Iron-sulfur proteins: A historical perspective Iron-Sulfur Clusters in Chemistry and Biology. 1-10. DOI: 10.1515/9783110308426.1 |
0.507 |
|
| 2014 |
Rouault TA. Iron-sulfur clusters in chemistry and biology Iron-Sulfur Clusters in Chemistry and Biology. 1-648. DOI: 10.1515/9783110308426 |
0.546 |
|
| 2013 |
Rouault TA. Iron metabolism in the CNS: implications for neurodegenerative diseases. Nature Reviews. Neuroscience. 14: 551-64. PMID 23820773 DOI: 10.1038/Nrn3453 |
0.54 |
|
| 2013 |
Lim SC, Friemel M, Marum JE, Tucker EJ, Bruno DL, Riley LG, Christodoulou J, Kirk EP, Boneh A, DeGennaro CM, Springer M, Mootha VK, Rouault TA, Leimkühler S, Thorburn DR, et al. Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. Human Molecular Genetics. 22: 4460-73. PMID 23814038 DOI: 10.1093/Hmg/Ddt295 |
0.568 |
|
| 2013 |
Linehan WM, Rouault TA. Molecular pathways: Fumarate hydratase-deficient kidney cancer--targeting the Warburg effect in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3345-52. PMID 23633457 DOI: 10.1158/1078-0432.Ccr-13-0304 |
0.407 |
|
| 2013 |
Uhrigshardt H, Rouault TA, Missirlis F. Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron-sulfur cluster enzyme activities and impaired iron homeostasis. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 18: 441-9. PMID 23444034 DOI: 10.1007/S00775-013-0988-2 |
0.622 |
|
| 2013 |
Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, ... ... Rouault TA, et al. Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. Cell Metabolism. 17: 271-81. PMID 23395173 DOI: 10.1016/J.Cmet.2012.12.016 |
0.747 |
|
| 2013 |
Crooks DR, Natarajan TG, Chen C, Huang H, Ghosh MC, Tong W, Haller RG, Wu C, Rouault TA. FGF-21 secretion and ketogenic enzyme expression are hallmarks of chronic energy deficiency in human skeletal muscles depleted of iron sulfur clusters Mitochondrion. 13: 904. DOI: 10.1016/J.Mito.2013.07.018 |
0.488 |
|
| 2012 |
Sourbier C, Srivastava G, Ghosh MC, Ghosh S, Yang Y, Gupta G, Degraff W, Krishna MC, Mitchell JB, Rouault TA, Linehan WM. Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma. Oncotarget. 3: 1472-82. PMID 23178531 DOI: 10.18632/Oncotarget.561 |
0.348 |
|
| 2012 |
Xia H, Cao Y, Dai X, Marelja Z, Zhou D, Mo R, Al-Mahdawi S, Pook MA, Leimkühler S, Rouault TA, Li K. Novel frataxin isoforms may contribute to the pathological mechanism of Friedreich ataxia. Plos One. 7: e47847. PMID 23082224 DOI: 10.1371/Journal.Pone.0047847 |
0.351 |
|
| 2012 |
Crooks DR, Jeong SY, Tong WH, Ghosh MC, Olivierre H, Haller RG, Rouault TA. Tissue specificity of a human mitochondrial disease: differentiation-enhanced mis-splicing of the Fe-S scaffold gene ISCU renders patient cells more sensitive to oxidative stress in ISCU myopathy. The Journal of Biological Chemistry. 287: 40119-30. PMID 23035118 DOI: 10.1074/Jbc.M112.418889 |
0.701 |
|
| 2012 |
Rouault TA. Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease. Disease Models & Mechanisms. 5: 155-64. PMID 22382365 DOI: 10.1242/dmm.009019 |
0.467 |
|
| 2012 |
Shi Y, Ghosh M, Kovtunovych G, Crooks DR, Rouault TA. Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis. Biochimica Et Biophysica Acta. 1823: 484-92. PMID 22101253 DOI: 10.1016/J.Bbamcr.2011.11.002 |
0.784 |
|
| 2012 |
Crooks DR, Natarajan TG, Chen C, Huang H, Ghosh MC, Tong W, Haller RG, Wu C, Rouault TA. Aberrant iron homeostasis, oxidative fiber enrichment, and activation of ketogenesis in muscle tissue of ISCU Myopathy patients Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-P58 |
0.695 |
|
| 2011 |
Jeong SY, Crooks DR, Wilson-Ollivierre H, Ghosh MC, Sougrat R, Lee J, Cooperman S, Mitchell JB, Beaumont C, Rouault TA. Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice. Plos One. 6: e25404. PMID 22003390 DOI: 10.1371/Journal.Pone.0025404 |
0.745 |
|
| 2011 |
Cameron JM, Janer A, Levandovskiy V, Mackay N, Rouault TA, Tong WH, Ogilvie I, Shoubridge EA, Robinson BH. Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes. American Journal of Human Genetics. 89: 486-95. PMID 21944046 DOI: 10.1016/J.Ajhg.2011.08.011 |
0.431 |
|
| 2011 |
Tong WH, Sourbier C, Kovtunovych G, Jeong SY, Vira M, Ghosh M, Romero VV, Sougrat R, Vaulont S, Viollet B, Kim YS, Lee S, Trepel J, Srinivasan R, Bratslavsky G, ... ... Rouault TA, et al. The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels. Cancer Cell. 20: 315-27. PMID 21907923 DOI: 10.1016/J.Ccr.2011.07.018 |
0.527 |
|
| 2011 |
Zhang DL, Senecal T, Ghosh MC, Ollivierre-Wilson H, Tu T, Rouault TA. Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts. Blood. 118: 2868-77. PMID 21700773 DOI: 10.1182/Blood-2011-01-330241 |
0.619 |
|
| 2011 |
Kosmidis S, Botella JA, Mandilaras K, Schneuwly S, Skoulakis EM, Rouault TA, Missirlis F. Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late-onset behavioral defects. Neurobiology of Disease. 43: 213-9. PMID 21440626 DOI: 10.1016/J.Nbd.2011.03.013 |
0.56 |
|
| 2010 |
Ye H, Rouault TA. Erythropoiesis and iron sulfur cluster biogenesis. Advances in Hematology. 2010. PMID 20862391 DOI: 10.1155/2010/329394 |
0.537 |
|
| 2010 |
Kovtunovych G, Eckhaus MA, Ghosh MC, Ollivierre-Wilson H, Rouault TA. Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. Blood. 116: 6054-62. PMID 20844238 DOI: 10.1182/Blood-2010-03-272138 |
0.513 |
|
| 2010 |
Li K, Singh A, Crooks DR, Dai X, Cong Z, Pan L, Ha D, Rouault TA. Expression of human frataxin is regulated by transcription factors SRF and TFAP2. Plos One. 5: e12286. PMID 20808827 DOI: 10.1371/Journal.Pone.0012286 |
0.621 |
|
| 2010 |
Uhrigshardt H, Singh A, Kovtunovych G, Ghosh M, Rouault TA. Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis. Human Molecular Genetics. 19: 3816-34. PMID 20668094 DOI: 10.1093/Hmg/Ddq301 |
0.461 |
|
| 2010 |
Ye H, Rouault TA. Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease. Biochemistry. 49: 4945-56. PMID 20481466 DOI: 10.1021/Bi1004798 |
0.618 |
|
| 2010 |
Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG. Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood. 116: 1574-84. PMID 20472835 DOI: 10.1182/Blood-2009-11-253815 |
0.704 |
|
| 2010 |
Bullock GC, Delehanty LL, Talbot AL, Gonias SL, Tong WH, Rouault TA, Dewar B, Macdonald JM, Chruma JJ, Goldfarb AN. Iron control of erythroid development by a novel aconitase-associated regulatory pathway. Blood. 116: 97-108. PMID 20407036 DOI: 10.1182/Blood-2009-10-251496 |
0.627 |
|
| 2010 |
Ye H, Jeong SY, Ghosh MC, Kovtunovych G, Silvestri L, Ortillo D, Uchida N, Tisdale J, Camaschella C, Rouault TA. Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. The Journal of Clinical Investigation. 120: 1749-61. PMID 20364084 DOI: 10.1172/Jci40372 |
0.658 |
|
| 2010 |
Shi ZH, Nie G, Duan XL, Rouault T, Wu WS, Ning B, Zhang N, Chang YZ, Zhao BL. Neuroprotective mechanism of mitochondrial ferritin on 6-hydroxydopamine-induced dopaminergic cell damage: implication for neuroprotection in Parkinson's disease. Antioxidants & Redox Signaling. 13: 783-96. PMID 20121342 DOI: 10.1089/Ars.2009.3018 |
0.504 |
|
| 2010 |
Crooks DR, Ghosh MC, Haller RG, Tong WH, Rouault TA. Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery. Blood. 115: 860-9. PMID 19965627 DOI: 10.1182/Blood-2009-09-243105 |
0.789 |
|
| 2010 |
Wang SM, Fu LJ, Duan XL, Crooks DR, Yu P, Qian ZM, Di XJ, Li J, Rouault TA, Chang YZ. Role of hepcidin in murine brain iron metabolism. Cellular and Molecular Life Sciences : Cmls. 67: 123-33. PMID 19898775 DOI: 10.1007/s00018-009-0167-3 |
0.742 |
|
| 2010 |
Rouault T. Multiple Causes of Iron Overload In Tissues, Cells and Subcellular Compartments Blood. 116: SCI-27-SCI-27. DOI: 10.1182/Blood.V116.21.Sci-27.Sci-27 |
0.639 |
|
| 2009 |
Rouault TA. Cell biology. An ancient gauge for iron. Science (New York, N.Y.). 326: 676-7. PMID 19900922 DOI: 10.1126/Science.1181938 |
0.573 |
|
| 2009 |
Rouault TA, Zhang DL, Jeong SY. Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins. Metabolic Brain Disease. 24: 673-84. PMID 19851851 DOI: 10.1007/S11011-009-9169-Y |
0.513 |
|
| 2009 |
Rouault TA, Tong WH. Tangled up in red: intertwining of the heme and iron-sulfur cluster biogenesis pathways. Cell Metabolism. 10: 80-1. PMID 19656484 DOI: 10.1016/J.Cmet.2009.07.007 |
0.526 |
|
| 2009 |
Shi Y, Ghosh MC, Tong WH, Rouault TA. Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Human Molecular Genetics. 18: 3014-25. PMID 19454487 DOI: 10.1093/Hmg/Ddp239 |
0.65 |
|
| 2009 |
Zhang DL, Hughes RM, Ollivierre-Wilson H, Ghosh MC, Rouault TA. A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression. Cell Metabolism. 9: 461-73. PMID 19416716 DOI: 10.1016/J.Cmet.2009.03.006 |
0.623 |
|
| 2009 |
Moyo VM, Mvundura E, Khumalo H, Gangaidzo IT, Saungweme T, Nouraie M, Rouault TA, Gomo ZA, Gordeuk VR. Serum ferritin concentrations in Africans with low dietary iron. Annals of Hematology. 88: 1131-6. PMID 19259672 DOI: 10.1007/S00277-009-0718-6 |
0.52 |
|
| 2009 |
Bullock GC, Delehanty LL, Talbot A, Gonias S, Tong W, Rouault T, Chruma J, Goldfarb A. Iron and Isocitrate Calibrate Erythropoietin Responsiveness of Erythroid Progenitors Via Aconitase Tuning of Protein Kinase C Activity. Blood. 114: 627-627. DOI: 10.1182/Blood.V114.22.627.627 |
0.617 |
|
| 2009 |
Rouault TA, Gordeuk V, Anderson G. The Central Role of the Liver in Iron Storage and Regulation of Systemic Iron Homeostasis The Liver: Biology and Pathobiology: Fifth Edition. 235-250. DOI: 10.1002/9780470747919.Ch16 |
0.565 |
|
| 2008 |
Ghosh MC, Tong WH, Zhang D, Ollivierre-Wilson H, Singh A, Krishna MC, Mitchell JB, Rouault TA. Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 12028-33. PMID 18685102 DOI: 10.1073/Pnas.0805361105 |
0.633 |
|
| 2008 |
Rouault TA, Tong WH. Iron-sulfur cluster biogenesis and human disease. Trends in Genetics : Tig. 24: 398-407. PMID 18606475 DOI: 10.1016/J.Tig.2008.05.008 |
0.539 |
|
| 2008 |
Li K, Besse EK, Ha D, Kovtunovych G, Rouault TA. Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia. Human Molecular Genetics. 17: 2265-73. PMID 18424449 DOI: 10.1093/Hmg/Ddn127 |
0.648 |
|
| 2008 |
Mochel F, Knight MA, Tong WH, Hernandez D, Ayyad K, Taivassalo T, Andersen PM, Singleton A, Rouault TA, Fischbeck KH, Haller RG. Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. American Journal of Human Genetics. 82: 652-60. PMID 18304497 DOI: 10.1016/J.Ajhg.2007.12.012 |
0.591 |
|
| 2007 |
Missirlis F, Kosmidis S, Brody T, Mavrakis M, Holmberg S, Odenwald WF, Skoulakis EM, Rouault TA. Homeostatic mechanisms for iron storage revealed by genetic manipulations and live imaging of Drosophila ferritin. Genetics. 177: 89-100. PMID 17603097 DOI: 10.1534/Genetics.107.075150 |
0.562 |
|
| 2007 |
Crooks DR, Ghosh MC, Braun-Sommargren M, Rouault TA, Smith DR. Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells. Journal of Neuroscience Research. 85: 1797-809. PMID 17469137 DOI: 10.1002/Jnr.21321 |
0.746 |
|
| 2007 |
Zhang D, Meyron-Holtz E, Rouault TA. Renal iron metabolism: transferrin iron delivery and the role of iron regulatory proteins. Journal of the American Society of Nephrology : Jasn. 18: 401-6. PMID 17229905 DOI: 10.1681/Asn.2006080908 |
0.622 |
|
| 2007 |
Tong WH, Rouault TA. Metabolic regulation of citrate and iron by aconitases: role of iron-sulfur cluster biogenesis. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 20: 549-64. PMID 17205209 DOI: 10.1007/S10534-006-9047-6 |
0.632 |
|
| 2006 |
Rouault TA, Cooperman S. Brain iron metabolism. Seminars in Pediatric Neurology. 13: 142-8. PMID 17101452 DOI: 10.1016/J.Spen.2006.08.002 |
0.587 |
|
| 2006 |
Rouault TA. The role of iron regulatory proteins in mammalian iron homeostasis and disease. Nature Chemical Biology. 2: 406-14. PMID 16850017 DOI: 10.1038/Nchembio807 |
0.649 |
|
| 2006 |
Lind MI, Missirlis F, Melefors O, Uhrigshardt H, Kirby K, Phillips JP, Söderhäll K, Rouault TA. Of two cytosolic aconitases expressed in Drosophila, only one functions as an iron-regulatory protein. The Journal of Biological Chemistry. 281: 18707-14. PMID 16679315 DOI: 10.1074/Jbc.M603354200 |
0.486 |
|
| 2006 |
Missirlis F, Holmberg S, Georgieva T, Dunkov BC, Rouault TA, Law JH. Characterization of mitochondrial ferritin in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 103: 5893-8. PMID 16571656 DOI: 10.1073/Pnas.0601471103 |
0.577 |
|
| 2006 |
Li K, Tong WH, Hughes RM, Rouault TA. Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly. The Journal of Biological Chemistry. 281: 12344-51. PMID 16527810 DOI: 10.1074/Jbc.M600582200 |
0.614 |
|
| 2006 |
Tong WH, Rouault TA. Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. Cell Metabolism. 3: 199-210. PMID 16517407 DOI: 10.1016/J.Cmet.2006.02.003 |
0.649 |
|
| 2006 |
Smith SR, Ghosh MC, Ollivierre-Wilson H, Hang Tong W, Rouault TA. Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development. Blood Cells, Molecules & Diseases. 36: 283-7. PMID 16480904 DOI: 10.1016/J.Bcmd.2005.12.006 |
0.56 |
|
| 2006 |
Ghosh MC, Ollivierre-Wilson H, Cooperman S, Rouault TA. Ghosh et al. reply [5] Nature Genetics. 38: 969-970. DOI: 10.1038/Ng0906-969 |
0.465 |
|
| 2005 |
Rouault TA. Linking physiological functions of iron. Nature Chemical Biology. 1: 193-4. PMID 16408033 DOI: 10.1038/Nchembio0905-193 |
0.61 |
|
| 2005 |
Wang RH, Li C, Xu X, Zheng Y, Xiao C, Zerfas P, Cooperman S, Eckhaus M, Rouault T, Mishra L, Deng CX. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metabolism. 2: 399-409. PMID 16330325 DOI: 10.1016/J.Cmet.2005.10.010 |
0.575 |
|
| 2005 |
Rouault TA. The intestinal heme transporter revealed. Cell. 122: 649-51. PMID 16143096 DOI: 10.1016/J.Cell.2005.08.027 |
0.524 |
|
| 2005 |
Salvatore MF, Fisher B, Surgener SP, Gerhardt GA, Rouault T. Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice. Brain Research. Molecular Brain Research. 139: 341-7. PMID 16051392 DOI: 10.1016/j.molbrainres.2005.06.002 |
0.315 |
|
| 2005 |
Hodges M, Yikilmaz E, Patterson G, Kasvosve I, Rouault TA, Gordeuk VR, Loyevsky M. An iron regulatory-like protein expressed in Plasmodium falciparum displays aconitase activity. Molecular and Biochemical Parasitology. 143: 29-38. PMID 15963579 DOI: 10.1016/J.Molbiopara.2005.05.004 |
0.552 |
|
| 2005 |
Yikilmaz E, Rouault TA, Schuck P. Self-association and ligand-induced conformational changes of iron regulatory proteins 1 and 2. Biochemistry. 44: 8470-8. PMID 15938636 DOI: 10.1021/Bi0500325 |
0.487 |
|
| 2005 |
Cooperman SS, Meyron-Holtz EG, Olivierre-Wilson H, Ghosh MC, McConnell JP, Rouault TA. Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. Blood. 106: 1084-91. PMID 15831703 DOI: 10.1182/Blood-2004-12-4703 |
0.587 |
|
| 2005 |
Rouault TA, Tong WH. Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis. Nature Reviews. Molecular Cell Biology. 6: 345-51. PMID 15803140 DOI: 10.1038/Nrm1620 |
0.621 |
|
| 2004 |
Meyron-Holtz EG, Ghosh MC, Rouault TA. Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo. Science (New York, N.Y.). 306: 2087-90. PMID 15604406 DOI: 10.1126/Science.1103786 |
0.594 |
|
| 2004 |
Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL. Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. Molecular Vision. 10: 598-607. PMID 15354085 |
0.538 |
|
| 2004 |
Jeong J, Rouault TA, Levine RL. Identification of a heme-sensing domain in iron regulatory protein 2. The Journal of Biological Chemistry. 279: 45450-4. PMID 15316013 DOI: 10.1074/Jbc.M407562200 |
0.606 |
|
| 2004 |
Smith SR, Cooperman S, Lavaute T, Tresser N, Ghosh M, Meyron-Holtz E, Land W, Ollivierre H, Jortner B, Switzer R, Messing A, Rouault TA. Severity of neurodegeneration correlates with compromise of iron metabolism in mice with iron regulatory protein deficiencies. Annals of the New York Academy of Sciences. 1012: 65-83. PMID 15105256 DOI: 10.1196/Annals.1306.006 |
0.519 |
|
| 2004 |
Wu LJ, Leenders AG, Cooperman S, Meyron-Holtz E, Smith S, Land W, Tsai RY, Berger UV, Sheng ZH, Rouault TA. Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier. Brain Research. 1001: 108-17. PMID 14972659 DOI: 10.1016/J.Brainres.2003.10.066 |
0.544 |
|
| 2004 |
Meyron-Holtz EG, Ghosh MC, Iwai K, LaVaute T, Brazzolotto X, Berger UV, Land W, Ollivierre-Wilson H, Grinberg A, Love P, Rouault TA. Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis Embo Journal. 23: 386-395. PMID 14726953 DOI: 10.1038/Sj.Emboj.7600041 |
0.621 |
|
| 2003 |
Rouault TA. How mammals acquire and distribute iron needed for oxygen-based metabolism. Plos Biology. 1: E79. PMID 14691550 DOI: 10.1371/journal.pbio.0000079 |
0.379 |
|
| 2003 |
Gordeuk VR, Caleffi A, Corradini E, Ferrara F, Jones RA, Castro O, Onyekwere O, Kittles R, Pignatti E, Montosi G, Garuti C, Gangaidzo IT, Gomo ZA, Moyo VM, Rouault TA, et al. Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene. Blood Cells, Molecules & Diseases. 31: 299-304. PMID 14636642 DOI: 10.1016/S1079-9796(03)00164-5 |
0.526 |
|
| 2003 |
Missirlis F, Hu J, Kirby K, Hilliker AJ, Rouault TA, Phillips JP. Compartment-specific protection of iron-sulfur proteins by superoxide dismutase. The Journal of Biological Chemistry. 278: 47365-9. PMID 12972424 DOI: 10.1074/Jbc.M307700200 |
0.579 |
|
| 2003 |
Bourdon E, Kang DK, Ghosh MC, Drake SK, Wey J, Levine RL, Rouault TA. The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2. Blood Cells, Molecules & Diseases. 31: 247-55. PMID 12972033 DOI: 10.1016/S1079-9796(03)00161-X |
0.623 |
|
| 2003 |
Rouault TA. Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis? Alcohol (Fayetteville, N.Y.). 30: 103-6. PMID 12957293 DOI: 10.1016/S0741-8329(03)00102-2 |
0.467 |
|
| 2003 |
Tong WH, Jameson GN, Huynh BH, Rouault TA. Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster. Proceedings of the National Academy of Sciences of the United States of America. 100: 9762-7. PMID 12886008 DOI: 10.1073/Pnas.1732541100 |
0.498 |
|
| 2003 |
Grabill C, Silva AC, Smith SS, Koretsky AP, Rouault TA. MRI detection of ferritin iron overload and associated neuronal pathology in iron regulatory protein-2 knockout mice. Brain Research. 971: 95-106. PMID 12691842 DOI: 10.1016/S0006-8993(03)02366-7 |
0.541 |
|
| 2003 |
Yamanaka K, Ishikawa H, Megumi Y, Tokunaga F, Kanie M, Rouault TA, Morishima I, Minato N, Ishimori K, Iwai K. Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2. Nature Cell Biology. 5: 336-40. PMID 12629548 DOI: 10.1038/Ncb952 |
0.491 |
|
| 2003 |
Loyevsky M, Mompoint F, Yikilmaz E, Altschul SF, Madden T, Wootton JC, Kurantsin-Mills J, Kassim OO, Gordeuk VR, Rouault TA. Expression of a recombinant IRP-like Plasmodium falciparum protein that specifically binds putative plasmodial IREs. Molecular and Biochemical Parasitology. 126: 231-8. PMID 12615322 DOI: 10.1016/S0166-6851(02)00278-5 |
0.406 |
|
| 2003 |
Allerson CR, Martinez A, Yikilmaz E, Rouault TA. A high-capacity RNA affinity column for the purification of human IRP1 and IRP2 overexpressed in Pichia pastoris. Rna (New York, N.Y.). 9: 364-74. PMID 12592010 DOI: 10.1261/Rna.2143303 |
0.375 |
|
| 2003 |
Kang DK, Jeong J, Drake SK, Wehr NB, Rouault TA, Levine RL. Iron regulatory protein 2 as iron sensor. Iron-dependent oxidative modification of cysteine. The Journal of Biological Chemistry. 278: 14857-64. PMID 12591920 DOI: 10.1074/Jbc.M300616200 |
0.599 |
|
| 2002 |
Rouault TA. Post-transcriptional regulation of human iron metabolism by iron regulatory proteins. Blood Cells, Molecules & Diseases. 29: 309-14. PMID 12547221 DOI: 10.1006/Bcmd.2002.0571 |
0.616 |
|
| 2002 |
Drake SK, Bourdon E, Wehr NB, Levine RL, Backlund PS, Yergey AL, Rouault TA. Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation. Developmental Neuroscience. 24: 114-24. PMID 12401949 DOI: 10.1159/000065693 |
0.611 |
|
| 2002 |
Rouault T. Commentary 2: Iron Metabolism and Mitochondrial Abnormalities in Friedreich Ataxia Blood Cells, Molecules, and Diseases. 29: 551-552. DOI: 10.1006/Bcmd.2002.0594 |
0.512 |
|
| 2001 |
Gunshin H, Allerson CR, Polycarpou-Schwarz M, Rofts A, Rogers JT, Kishi F, Hentze MW, Rouault TA, Andrews NC, Hediger MA. Iron-dependent regulation of the divalent metal ion transporter. Febs Letters. 509: 309-16. PMID 11741608 DOI: 10.1016/S0014-5793(01)03189-1 |
0.575 |
|
| 2001 |
Loyevsky M, LaVaute T, Allerson CR, Stearman R, Kassim OO, Cooperman S, Gordeuk VR, Rouault TA. An IRP-like protein from Plasmodium falciparum binds to a mammalian iron-responsive element Blood. 98: 2555-2562. PMID 11588054 DOI: 10.1182/blood.V98.8.2555 |
0.496 |
|
| 2001 |
Rouault TA. Systemic iron metabolism: a review and implications for brain iron metabolism Pediatric Neurology. 25: 130-137. PMID 11551743 DOI: 10.1016/S0887-8994(01)00260-0 |
0.546 |
|
| 2001 |
Gangaidzo IT, Moyo VM, Mvundura E, Aggrey G, Murphree NL, Khumalo H, Saungweme T, Kasvosve I, Gomo ZA, Rouault T, Boelaert JR, Gordeuk VR. Association of pulmonary tuberculosis with increased dietary iron. The Journal of Infectious Diseases. 184: 936-9. PMID 11528590 DOI: 10.1086/323203 |
0.484 |
|
| 2001 |
Rouault TA. Iron on the brain Nature Genetics. 28: 299-300. PMID 11479580 DOI: 10.1038/91036 |
0.541 |
|
| 2001 |
Bolan CD, Conry-Cantilena C, Mason G, Rouault TA, Leitman SF. MCV as a guide to phlebotomy therapy for hemochromatosis Transfusion. 41: 819-827. PMID 11399827 DOI: 10.1046/J.1537-2995.2001.41060819.X |
0.528 |
|
| 2001 |
LaVaute T, Smith S, Cooperman S, Iwai K, Land W, Meyron-Holtz E, Drake SK, Miller G, Abu-Asab M, Tsokos M, Switzer R, Grinberg A, Love P, Tresser N, Rouault TA. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nature Genetics. 27: 209-14. PMID 11175792 DOI: 10.1038/84859 |
0.633 |
|
| 2000 |
Tong W, Rouault T. Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells. The Embo Journal. 19: 5692-5700. PMID 11060020 DOI: 10.1093/Emboj/19.21.5692 |
0.456 |
|
| 2000 |
Rouault TA, Harford JB. 21 Translational Control of Ferritin Synthesis Cold Spring Harbor Monograph Archive. 39: 655-670. DOI: 10.1101/087969618.39.655 |
0.63 |
|
| 2000 |
Moyo VM, Mvundura E, Khumalo H, Gomo ZA, Rouault TA, Gordeuk VR, Gangaidzo IT. Iron stores as reflected in serum ferritin concentrations en Africans with low dietary iron Blood. 96. |
0.455 |
|
| 1999 |
Meyron-Holtz EG, Vaisman B, Cabantchik ZI, Fibach E, Rouault TA, Hershko C, Konijn AM. Regulation of intracellular iron metabolism in human erythroid precursors by internalized extracellular ferritin Blood. 94: 3205-3211. PMID 10556209 |
0.552 |
|
| 1999 |
MacPhail AP, Mandishona EM, Bloom PD, Paterson AC, Rouault TA, Gordeuk VR. Measurements of iron status and survival in African iron overload South African Medical Journal. 89: 966-972. PMID 10554633 |
0.474 |
|
| 1999 |
Allerson CR, Cazzola M, Rouault TA. Clinical severity and thermodynamic effects of iron-responsive element mutations in hereditary hyperferritinemia-cataract syndrome Journal of Biological Chemistry. 274: 26439-26447. PMID 10473603 DOI: 10.1074/Jbc.274.37.26439 |
0.476 |
|
| 1999 |
Gangaidzo IT, Moyo VM, Saungweme T, Khumalo H, Charakupa RM, Gomo ZAR, Loyevsky M, Stearman R, La Vaute T, Enquist EG, Rouault TA, Gordeuk VR. Iron overload in urban Africans in the 1990s Gut. 45: 278-283. PMID 10403742 DOI: 10.1136/Gut.45.2.278 |
0.579 |
|
| 1999 |
McNamara L, MacPhail AP, Mandishona E, Bloom P, Paterson AC, Rouault TA, Gordeuk VR. Non-transferrin-bound iron and hepatic dysfunction in African dietary iron overload Journal of Gastroenterology and Hepatology (Australia). 14: 126-132. DOI: 10.1046/J.1440-1746.1999.01830.X |
0.564 |
|
| 1998 |
Land T, Rouault TA. Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization Molecular Cell. 2: 807-815. PMID 9885568 DOI: 10.1016/S1097-2765(00)80295-6 |
0.542 |
|
| 1998 |
McNamara L, MacPhail AP, Gordeuk VR, Hasstedt SJ, Rouault T. Is there a link between African iron overload and the described mutations of the hereditary haemochromatosis gene British Journal of Haematology. 102: 1176-1178. PMID 9753041 DOI: 10.1046/J.1365-2141.1998.00917.X |
0.504 |
|
| 1998 |
Philpott CC, Rashford J, Yamaguchi-Iwai Y, Rouault TA, Dancis A, Klausner RD. Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast. The Embo Journal. 17: 5026-36. PMID 9724638 DOI: 10.1093/Emboj/17.17.5026 |
0.597 |
|
| 1998 |
Khumalo H, Gomo ZAR, Gangaidzo IT, Moyo VM, Mandishona E, Saungweme T, Rouault TA, Gordeuk VR, Patrick MacPhail A. Effect of ascorbic acid administration on serum concentration of transferrin receptors Clinical Chemistry. 44: 1573-1575. PMID 9665447 DOI: 10.1093/Clinchem/44.7.1573 |
0.602 |
|
| 1998 |
Mandishona E, MacPhail AP, Gordeuk VR, Kedda MA, Paterson AC, Rouault TA, Kew MC. Dietary iron overload as a risk factor for hepatocellular carcinoma in Black Africans Hepatology. 27: 1563-1566. PMID 9620327 DOI: 10.1002/Hep.510270614 |
0.445 |
|
| 1998 |
Iwai K, Drake SK, Wehr NB, Weissman AM, LaVaute T, Minato N, Klausner RD, Levine RL, Rouault TA. Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins. Proceedings of the National Academy of Sciences of the United States of America. 95: 4924-8. PMID 9560204 DOI: 10.1073/Pnas.95.9.4924 |
0.569 |
|
| 1998 |
Khumalo H, Gomo ZAR, Moyo VM, Gordeuk VR, Saungweme T, Rouault TA, Gangaidzo IT. Serum transferrin receptors are decreased in the presence of iron overload Clinical Chemistry. 44: 40-44. PMID 9550556 DOI: 10.1093/Clinchem/44.1.40 |
0.479 |
|
| 1998 |
Moyo VM, Makunike R, Gangaidzo IT, Gordeuk VR, McLaren CE, Khumalo H, Saungweme T, Rouault T, Kiire CF. African iron overload and hepatocellular carcinoma (HA-7-0-080). European Journal of Haematology. 60: 28-34. PMID 9451425 DOI: 10.1111/J.1600-0609.1998.Tb00993.X |
0.494 |
|
| 1998 |
Moyo VM, Mandishona E, Hasstedt SJ, Gangaidzo IT, Gomo ZAR, Khumalo H, Saungweme T, Kiire CF, Paterson AC, Bloom P, MacPhail AP, Rouault T, Gordeuk VR. Evidence of genetic transmission in African iron overload. Blood. 91: 1076-1082. DOI: 10.1182/Blood.V91.3.1076 |
0.585 |
|
| 1998 |
Harford JB, Rouault TA. RNA Structure and Function in Cellular Iron Homeostasis Cold Spring Harbor Monograph Archive. 35: 575-602. DOI: 10.1101/087969509.35.575 |
0.59 |
|
| 1997 |
Addess KJ, Basilion JP, Klausner RD, Rouault TA, Pardi A. Structure and dynamics of the iron responsive element RNA: implications for binding of the RNA by iron regulatory binding proteins. Journal of Molecular Biology. 274: 72-83. PMID 9398517 DOI: 10.1006/Jmbi.1997.1377 |
0.47 |
|
| 1997 |
Rouault T, Klausner R. Regulation of iron metabolism in eukaryotes. Current Topics in Cellular Regulation. 35: 1-19. PMID 9192174 DOI: 10.1016/S0070-2137(97)80001-5 |
0.624 |
|
| 1997 |
Moyo VM, Gangaidzo IT, Gomo Z, Khumalo H, Saungweme T, Kiire C, Rouault T, Gordeuk VR. Traditional Beer Consumption and the Iron Status of Spouse Pairs From a Rural Community in Zimbabwe Blood. 89: 2159-2166. DOI: 10.1182/Blood.V89.6.2159 |
0.566 |
|
| 1996 |
Rouault TA, Klausner RD. Iron-sulfur clusters as biosensors of oxidants and iron. Trends in Biochemical Sciences. 21: 174-7. PMID 8871401 DOI: 10.1016/S0968-0004(96)10024-4 |
0.609 |
|
| 1996 |
Rouault TA, Klausner RD. The impact of oxidative stress on eukaryotic iron metabolism. Exs. 77: 183-97. PMID 8856975 |
0.565 |
|
| 1996 |
Kim HY, LaVaute T, Iwai K, Klausner RD, Rouault TA. Identification of a conserved and functional iron-responsive element in the 5'-untranslated region of mammalian mitochondrial aconitase. The Journal of Biological Chemistry. 271: 24226-30. PMID 8798666 DOI: 10.1074/Jbc.271.39.24226 |
0.6 |
|
| 1996 |
Butt J, Kim HY, Basilion JP, Cohen S, Iwai K, Philpott CC, Altschul S, Klausner RD, Rouault TA. Differences in the RNA binding sites of iron regulatory proteins and potential target diversity. Proceedings of the National Academy of Sciences of the United States of America. 93: 4345-9. PMID 8633068 DOI: 10.1073/Pnas.93.9.4345 |
0.434 |
|
| 1996 |
Rouault TA, Klausner RD, Harford JB. 12 Translational Control of Ferritin Cold Spring Harbor Monograph Archive. 30: 335-362. DOI: 10.1101/087969458.30.335 |
0.49 |
|
| 1996 |
Rouault TA, Klausner RD. Post-transcriptional regulation of genes of iron metabolism in mammalian cells Journal of Biological Inorganic Chemistry. 1: 494-499. DOI: 10.1007/S007750050083 |
0.632 |
|
| 1995 |
Kim HY, Klausner RD, Rouault TA. Translational repressor activity is equivalent and is quantitatively predicted by in vitro RNA binding for two iron-responsive element-binding proteins, IRP1 and IRP2. The Journal of Biological Chemistry. 270: 4983-6. PMID 7890603 DOI: 10.1074/Jbc.270.10.4983 |
0.465 |
|
| 1995 |
DeRusso PA, Philpott CC, Iwai K, Mostowski HS, Klausner RD, Rouault TA. Expression of a constitutive mutant of iron regulatory protein 1 abolishes iron homeostasis in mammalian cells. The Journal of Biological Chemistry. 270: 15451-4. PMID 7541043 DOI: 10.1074/Jbc.270.26.15451 |
0.617 |
|
| 1995 |
Iwai K, Klausner RD, Rouault TA. Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2. The Embo Journal. 14: 5350-7. PMID 7489724 DOI: 10.1002/J.1460-2075.1995.Tb00219.X |
0.595 |
|
| 1994 |
Basilion JP, Rouault TA, Massinople CM, Klausner RD, Burgess WH. The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft. Proceedings of the National Academy of Sciences of the United States of America. 91: 574-8. PMID 8290565 DOI: 10.1073/Pnas.91.2.574 |
0.512 |
|
| 1994 |
Basilion JP, Kennedy MC, Beinert H, Massinople CM, Klausner RD, Rouault TA. Overexpression of iron-responsive element-binding protein and its analytical characterization as the RNA-binding form, devoid of an iron-sulfur cluster. Archives of Biochemistry and Biophysics. 311: 517-22. PMID 8203918 DOI: 10.1006/abbi.1994.1270 |
0.51 |
|
| 1994 |
Philpott CC, Klausner RD, Rouault TA. The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation. Proceedings of the National Academy of Sciences of the United States of America. 91: 7321-5. PMID 8041788 DOI: 10.1073/Pnas.91.15.7321 |
0.53 |
|
| 1994 |
Samaniego F, Chin J, Iwai K, Rouault TA, Klausner RD. Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation. The Journal of Biological Chemistry. 269: 30904-10. PMID 7983023 |
0.483 |
|
| 1994 |
Gordeuk VR, Mclaren GD, Samowitz W, Rouault TA. Etiologies, consequences, and treatment of iron overload Critical Reviews in Clinical Laboratory Sciences. 31: 89-133. PMID 7917009 DOI: 10.3109/10408369409084674 |
0.517 |
|
| 1994 |
Jaffrey SR, Cohen NA, Rouault TA, Klausner RD, Snyder SH. The iron-responsive element binding protein: a target for synaptic actions of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 91: 12994-8. PMID 7809162 DOI: 10.1073/Pnas.91.26.12994 |
0.497 |
|
| 1994 |
Klausner RD, Stout CD, Rouault TA. Dispensable iron-sulfur clusters: the interconversion of aconitase with the RNA-binding protein, IRE-BP Chemistry and Biology. 1: xiv-xv. DOI: 10.1016/1074-5521(94)90024-8 |
0.515 |
|
| 1993 |
Klausner RD, Rouault TA, Harford JB. Regulating the fate of mRNA: The control of cellular iron metabolism Cell. 72: 19-28. PMID 8380757 DOI: 10.1016/0092-8674(93)90046-S |
0.517 |
|
| 1993 |
Philpott CC, Haile D, Rouault TA, Klausner RD. Modification of a free Fe-S cluster cysteine residue in the active iron-responsive element-binding protein prevents RNA binding. The Journal of Biological Chemistry. 268: 17655-8. PMID 8349646 |
0.387 |
|
| 1993 |
Rouault T, Haile D, Massinople C, Philpott C, Basilion J, Klausner R. The state of the iron-sulfur cluster of the iron-responsive element binding protein determines whether the protein will function as an RNA regulatory protein or as a cytosolic enzyme Journal of Inorganic Biochemistry. 51: 581. DOI: 10.1016/0162-0134(93)85603-6 |
0.469 |
|
| 1993 |
Kennedy M, Beinert H, Rouault T, Klausner R. Aconitase, the janus-faced protein: Tricarboxylate (DE)hydratase and iron regulating protein. Journal of Inorganic Biochemistry. 51: 442. DOI: 10.1016/0162-0134(93)85470-S |
0.411 |
|
| 1992 |
Haile DJ, Rouault TA, Tang CK, Chin J, Harford JB, Klausner RD. Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: Role of the iron-sulfur cluster Proceedings of the National Academy of Sciences of the United States of America. 89: 7536-7540. PMID 1502165 DOI: 10.1073/Pnas.89.16.7536 |
0.617 |
|
| 1992 |
Tang CK, Chin J, Harford JB, Klausner RD, Rouault TA. Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation Journal of Biological Chemistry. 267: 24466-24470. PMID 1447194 |
0.539 |
|
| 1992 |
Rouault TA, Haile DJ, Downey WE, Philpott CC, Tang C, Samaniego F, Chin J, Paul I, Orloff D, Harford JB, Klausner RD. An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein Biometals. 5: 131-140. PMID 1421965 DOI: 10.1007/Bf01061319 |
0.604 |
|
| 1992 |
Haile DJ, Rouault TA, Harford JB, Kennedy MC, Blondin GA, Beinert H, Klausner RD. Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding. Proceedings of the National Academy of Sciences of the United States of America. 89: 11735-9. PMID 1281544 DOI: 10.1073/Pnas.89.24.11735 |
0.617 |
|
| 1991 |
Rouault TA, Stout CD, Kaptain S, Harford JB, Klausner RD. Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: Functional implications Cell. 64: 881-883. PMID 2001588 DOI: 10.1016/0092-8674(91)90312-M |
0.492 |
|
| 1991 |
Philpott CC, Rouault TA, Klausner RD. Sequence and expression of the murine iron-responsive element binding protein Nucleic Acids Research. 19: 6333. PMID 1956798 DOI: 10.1093/Nar/19.22.6333 |
0.494 |
|
| 1991 |
Kaptain S, Downey WE, Tang C, Philpott C, Haile D, Orloff DG, Harford JB, Rouault TA, Klausner RD. A regulated RNA binding protein also possesses aconitase activity Proceedings of the National Academy of Sciences of the United States of America. 88: 10109-10113. PMID 1946430 DOI: 10.1073/Pnas.88.22.10109 |
0.366 |
|
| 1990 |
Haile DJ, Rouault TA, Harford JB, Klausner RD. The inhibition of the iron responsive element RNA-protein interaction by heme does not mimic in vivo iron regulation Journal of Biological Chemistry. 265: 12786-12789. PMID 2376574 |
0.358 |
|
| 1990 |
Rouault TA, Tang CK, Kaptain S, Burgess WH, Haile DJ, Samaniego F, Wesley Mcbride O, Harford JB, Klausner RD. Cloning of the cDNA encoding an RNA regulatory protein - The human iron-responsive element-binding protein Proceedings of the National Academy of Sciences of the United States of America. 87: 7958-7962. PMID 2172968 DOI: 10.1073/Pnas.87.20.7958 |
0.45 |
|
| 1989 |
Hentze MW, Rouault TA, Harford JB, Klausner RD. Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. Science (New York, N.Y.). 244: 357-9. PMID 2711187 DOI: 10.1126/Science.2711187 |
0.492 |
|
| 1989 |
Haile DJ, Hentze MW, Rouault TA, Harford JB, Klausner RD. Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements Molecular and Cellular Biology. 9: 5055-50619. PMID 2601708 DOI: 10.1128/Mcb.9.11.5055 |
0.524 |
|
| 1989 |
Rouault TA, Hentze MW, Haile DJ, Harford JB, Klausner RD. The iron-responsive element binding protein: A method for the affinity purification of a regulatory RNA-binding protein Proceedings of the National Academy of Sciences of the United States of America. 86: 5768-5772. PMID 2474819 DOI: 10.1073/Pnas.86.15.5768 |
0.406 |
|
| 1988 |
Rouault TA, Hentze MW, Caughman SW, Harford JB, Klausner RD. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science (New York, N.Y.). 241: 1207-10. PMID 3413484 DOI: 10.1126/Science.3413484 |
0.542 |
|
| 1988 |
Hentze MW, Caughman SW, Casey JL, Koeller DM, Rouault TA, Harford JB, Klausner RD. A model for the structure and functions of iron-responsive elements. Gene. 72: 201-8. PMID 3266604 DOI: 10.1016/0378-1119(88)90145-X |
0.546 |
|
| 1988 |
Caughman SW, Hentze MW, Rouault TA, Harford JB, Klausner RD. The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor. The Journal of Biological Chemistry. 263: 19048-52. PMID 3198610 |
0.516 |
|
| 1988 |
Casey JL, Hentze MW, Koeller DM, Caughman SW, Rouault TA, Klausner RD, Harford JB. Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. Science (New York, N.Y.). 240: 924-8. PMID 2452485 DOI: 10.1126/Science.2452485 |
0.549 |
|
| 1987 |
Hentze MW, Caughman SW, Rouault TA, Barriocanal JG, Dancis A, Harford JB, Klausner RD. Identification of the iron-responsive element for the translational regulation of human ferritin mRNA. Science (New York, N.Y.). 238: 1570-3. PMID 3685996 DOI: 10.1126/Science.3685996 |
0.585 |
|
| 1987 |
Hentze MW, Rouault TA, Caughman SW, Dancis A, Harford JB, Klausner RD. A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. Proceedings of the National Academy of Sciences of the United States of America. 84: 6730-4. PMID 3477805 DOI: 10.1073/Pnas.84.19.6730 |
0.58 |
|
| 1987 |
Rouault TA, Hentze MW, Dancis A, Caughman W, Harford JB, Klausner RD. Influence of altered transcription on the translational control of human ferritin expression Proceedings of the National Academy of Sciences of the United States of America. 84: 6335-6339. PMID 3476949 DOI: 10.1073/Pnas.84.18.6335 |
0.471 |
|
| 1986 |
Rao K, Harford JB, Rouault T, McClelland A, Ruddle FH, Klausner RD. Transcriptional regulation by iron of the gene for the transferrin receptor. Molecular and Cellular Biology. 6: 236-40. PMID 3785148 DOI: 10.1128/Mcb.6.1.236 |
0.491 |
|
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