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Kevin M. Dean, Ph.D. - Publications

Affiliations: 
2002-2006 Chemistry Willamette University, Salem, OR, United States 
 2007-2014 Chemistry and Biochemistry University of Colorado, Boulder, Boulder, CO, United States 
 2014- Cell Biology and Bioinformatics University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Biochemistry, General Biophysics
Website:
www.kevinmdean.com
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Roudot P, Legant WR, Zou Q, Dean KM, Isogai T, Welf ES, David AF, Gerlich DW, Fiolka R, Betzig E, Danuser G. u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions. Cell Reports Methods. 100655. PMID 38042149 DOI: 10.1016/j.crmeth.2023.100655  0.692
2023 Nanes BA, Bhatt K, Azarova E, Rajendran D, Isogai T, Dean KM, Danuser G. Keratin isoform shifts modulate motility signals during wound healing. Biorxiv : the Preprint Server For Biology. PMID 37205459 DOI: 10.1101/2023.05.04.538989  0.463
2023 Weems AD, Welf ES, Driscoll MK, Zhou FY, Mazloom-Farsibaf H, Chang BJ, Murali VS, Gihana GM, Weiss BG, Chi J, Rajendran D, Dean KM, Fiolka R, Danuser G. Blebs promote cell survival by assembling oncogenic signalling hubs. Nature. PMID 36859545 DOI: 10.1038/s41586-023-05758-6  0.718
2022 Chen B, Chang BJ, Zhou FY, Daetwyler S, Sapoznik E, Nanes BA, Terrazas I, Gihana GM, Castro LP, Chan IS, Conacci-Sorrell M, Dean KM, Millett-Sikking A, York AG, Fiolka R. Increasing the field-of-view in oblique plane microscopy via optical tiling. Biomedical Optics Express. 13: 5616-5627. PMID 36733723 DOI: 10.1364/BOE.467969  0.707
2022 Chen B, Chang BJ, Roudot P, Zhou F, Sapoznik E, Marlar-Pavey M, Hayes JB, Brown PT, Zeng CW, Lambert T, Friedman JR, Zhang CL, Burnette DT, Shepherd DP, Dean KM, et al. Resolution doubling in light-sheet microscopy via oblique plane structured illumination. Nature Methods. PMID 36280718 DOI: 10.1038/s41592-022-01635-8  0.742
2022 Dean KM, Chakraborty T, Daetwyler S, Lin J, Garrelts G, M'Saad O, Mekbib HT, Voigt FF, Schaettin M, Stoeckli ET, Helmchen F, Bewersdorf J, Fiolka R. Isotropic imaging across spatial scales with axially swept light-sheet microscopy. Nature Protocols. PMID 35831614 DOI: 10.1038/s41596-022-00706-6  0.727
2021 Liu H, Hiremath C, Patterson Q, Vora S, Shang Z, Jamieson A, Fiolka R, Dean K, Dellinger M, Marciano D. Heterozygous Mutation of Reduces Renal Lymphatics Without Renal Dysfunction. Journal of the American Society of Nephrology : Jasn. PMID 34551997 DOI: 10.1681/ASN.2021010061  0.586
2021 Chang BJ, Manton JD, Sapoznik E, Pohlkamp T, Terrones TS, Welf ES, Murali VS, Roudot P, Hake K, Whitehead L, York AG, Dean KM, Fiolka R. Real-time multi-angle projection imaging of biological dynamics. Nature Methods. PMID 34183831 DOI: 10.1038/s41592-021-01175-7  0.693
2021 Han SJ, Azarova EV, Whitewood AJ, Bachir A, Guttierrez E, Groisman A, Horwitz AR, Goult BT, Dean KM, Danuser G. Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation. Elife. 10. PMID 33783351 DOI: 10.7554/eLife.66151  0.453
2020 Welf ES, Miles CE, Huh J, Sapoznik E, Chi J, Driscoll MK, Isogai T, Noh J, Weems AD, Pohlkamp T, Dean K, Fiolka R, Mogilner A, Danuser G. Actin-Membrane Release Initiates Cell Protrusions. Developmental Cell. PMID 33308479 DOI: 10.1016/j.devcel.2020.11.024  0.695
2020 Sapoznik E, Chang BJ, Huh J, Ju RJ, Azarova EV, Pohlkamp T, Welf ES, Broadbent D, Carisey AF, Stehbens SJ, Lee KM, Marin A, Hanker AB, Schmidt JC, Arteaga CL, ... ... Dean KM, et al. A versatile Oblique Plane Microscope for large-scale and high-resolution imaging of subcellular dynamics. Elife. 9. PMID 33179596 DOI: 10.7554/eLife.57681  0.706
2020 Lee KM, Guerrero-Zotano AL, Servetto A, Sudhan DR, Lin CC, Formisano L, Jansen VM, González-Ericsson P, Sanders ME, Stricker TP, Raj G, Dean KM, Fiolka R, Cantley LC, Hanker AB, et al. Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer. Nature Communications. 11: 5488. PMID 33127913 DOI: 10.1038/s41467-020-19291-x  0.574
2020 Chakraborty T, Chen B, Daetwyler S, Chang BJ, Vanderpoorten O, Sapoznik E, Kaminski CF, Knowles TPJ, Dean KM, Fiolka R. Converting lateral scanning into axial focusing to speed up three-dimensional microscopy. Light, Science & Applications. 9: 165. PMID 33024553 DOI: 10.1038/s41377-020-00401-9  0.706
2020 Chen B, Chakraborty T, Daetwyler S, Manton JD, Dean K, Fiolka R. Extended depth of focus multiphoton microscopy via incoherent pulse splitting. Biomedical Optics Express. 11: 3830-3842. PMID 33014569 DOI: 10.1364/Boe.393931  0.734
2020 Chang BJ, Dean KM, Fiolka R. Systematic and quantitative comparison of lattice and Gaussian light-sheets. Optics Express. 28: 27052-27077. PMID 32906967 DOI: 10.1364/Oe.400164  0.701
2019 Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, Hiremath C, De La Cruz ED, Yi Y, Bezprozvanny I, ... ... Dean KM, et al. Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution. Nature Methods. 16: 1109-1113. PMID 31673159 DOI: 10.1038/S41592-019-0615-4  0.77
2019 Driscoll MK, Welf ES, Jamieson AR, Dean KM, Isogai T, Fiolka R, Danuser G. Robust and automated detection of subcellular morphological motifs in 3D microscopy images. Nature Methods. PMID 31501548 DOI: 10.1038/S41592-019-0539-Z  0.752
2019 Mohan AS, Dean KM, Isogai T, Kasitinon SY, Murali VS, Roudot P, Groisman A, Reed DK, Welf ES, Han SJ, Noh J, Danuser G. Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1 Melanoma Cells. Developmental Cell. 49: 444-460.e9. PMID 31063759 DOI: 10.1016/J.Devcel.2019.04.007  0.543
2019 Chang BJ, Kittisopikul M, Dean KM, Roudot P, Welf ES, Fiolka R. Universal light-sheet generation with field synthesis. Nature Methods. PMID 30804550 DOI: 10.1038/S41592-019-0327-9  0.68
2018 Mohan A, Dean K, Murali V, Yuan S, Isogai T, Han S, Welf E, Danuser G. 1264 Rac1P29S coordinates the actin cytoskeleton to mediate a mechanosensitive proliferative advantage in melanoma Journal of Investigative Dermatology. 138: S214. DOI: 10.1016/J.Jid.2018.03.1279  0.497
2018 Fiolka RP, Dean KM, Driscoll M, Welf E, Danuser G. Quantitative Imaging of Cellular Morphodynamics and Signaling with Light-Sheet Microscopy Biophysical Journal. 114: 6a-7a. DOI: 10.1016/J.Bpj.2017.11.068  0.764
2017 Dean KM, Roudot P, Welf ES, Pohlkamp T, Garrelts G, Herz J, Fiolka R. Imaging Subcellular Dynamics with Fast and Light-Efficient Volumetrically Parallelized Microscopy. Optica. 4: 263-271. PMID 28944279 DOI: 10.1364/OPTICA.4.000263  0.735
2017 Dean KM, Fiolka R. Lossless Three-Dimensional Parallelization in Digitally Scanned Light-Sheet Fluorescence Microscopy. Scientific Reports. 7: 9332. PMID 28839150 DOI: 10.1038/S41598-017-08113-8  0.761
2017 Mohan A, Dean K, Han S, Welf E, Danuser G. LB993 Focal adhesions mediate Rac1P29S-dependent drug resistance to MAPK inhibitors in melanoma Journal of Investigative Dermatology. 137: B11. DOI: 10.1016/J.Jid.2017.07.075  0.477
2016 Chu J, Oh Y, Sens A, Ataie N, Dana H, Macklin JJ, Laviv T, Welf ES, Dean KM, Zhang F, Kim BB, Tang CT, Hu M, Baird MA, Davidson MW, et al. A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo. Nature Biotechnology. PMID 27240196 DOI: 10.1038/Nbt.3550  0.753
2016 Williamson JC, Brown AM, Helvie EN, Dean KM. Determination of liquid-liquid critical point composition using 90^{∘} laser light scattering. Physical Review. E. 93: 042610. PMID 27176355 DOI: 10.1103/Physreve.93.042610  0.412
2016 Dean KM, Roudot P, Reis CR, Welf ES, Mettlen M, Fiolka R. Diagonally Scanned Light-Sheet Microscopy for Fast Volumetric Imaging of Adherent Cells. Biophysical Journal. 110: 1456-65. PMID 27028654 DOI: 10.1016/J.Bpj.2016.01.029  0.751
2016 Welf ES, Driscoll MK, Dean KM, Schäfer C, Chu J, Davidson MW, Lin MZ, Danuser G, Fiolka R. Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments. Developmental Cell. 36: 462-75. PMID 26906741 DOI: 10.1016/J.Devcel.2016.01.022  0.761
2016 Dean KM, Driscoll MK, Welf ES, Fiolka R. Microscope technologies for quantitative imaging in 3D microenvironments Spie Newsroom. DOI: 10.1117/2.1201608.006670  0.674
2015 Dean KM, Roudot P, Welf ES, Danuser G, Fiolka R. Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy. Biophysical Journal. 108: 2807-15. PMID 26083920 DOI: 10.1016/J.Bpj.2015.05.013  0.806
2015 Dean KM, Davis LM, Lubbeck JL, Manna P, Friis P, Palmer AE, Jimenez R. High-speed multiparameter photophysical analyses of fluorophore libraries. Analytical Chemistry. 87: 5026-30. PMID 25898152 DOI: 10.1021/Acs.Analchem.5B00607  0.803
2015 Dean KM, Lubbeck JL, Davis LM, Regmi CK, Chapagain PP, Gerstman BS, Jimenez R, Palmer AE. Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 263-73. PMID 25477249 DOI: 10.1039/C4Ib00251B  0.816
2015 Dean KM, Roudot P, Welf ES, Danuser G, Fiolka R. Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy Biophysical Journal. 108: 2807-2815. DOI: 10.1016/j.bpj.2015.05.013  0.753
2014 Dean KM, Fiolka R. Uniform and scalable light-sheets generated by extended focusing. Optics Express. 22: 26141-52. PMID 25401646 DOI: 10.1364/OE.22.026141  0.718
2014 Dean KM, Palmer AE. Advances in fluorescence labeling strategies for dynamic cellular imaging. Nature Chemical Biology. 10: 512-23. PMID 24937069 DOI: 10.1038/Nchembio.1556  0.708
2014 Dean KM, Davis LM, Lubbeck JL, Manna P, Palmer AE, Jimenez R. Microfluidic flow cytometer for multiparameter screening of fluorophore photophysics Conference On Lasers and Electro-Optics Europe - Technical Digest. 2014.  0.798
2013 Qin Y, Miranda JG, Stoddard CI, Dean KM, Galati DF, Palmer AE. Direct comparison of a genetically encoded sensor and small molecule indicator: implications for quantification of cytosolic Zn(2+). Acs Chemical Biology. 8: 2366-71. PMID 23992616 DOI: 10.1021/Cb4003859  0.661
2013 Davis LM, Lubbeck JL, Dean KM, Palmer AE, Jimenez R. Microfluidic cell sorter for use in developing red fluorescent proteins with improved photostability. Lab On a Chip. 13: 2320-7. PMID 23636097 DOI: 10.1039/C3Lc50191D  0.821
2012 Dean KM, Qin Y, Palmer AE. Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes. Biochimica Et Biophysica Acta. 1823: 1406-15. PMID 22521452 DOI: 10.1016/J.Bbamcr.2012.04.001  0.662
2012 Lubbeck JL, Dean KM, Ma H, Palmer AE, Jimenez R. Microfluidic flow cytometer for quantifying photobleaching of fluorescent proteins in cells. Analytical Chemistry. 84: 3929-37. PMID 22424298 DOI: 10.1021/Ac202825Z  0.813
2012 Davis LM, Lubbeck JL, Dean KM, Palmer AE, Jimenez R. Real-time analysis of multi-laser-beam fluorescence for timed control of laser tweezers in a microfluidic cell-sorting device Proceedings of Spie - the International Society For Optical Engineering. 8412. DOI: 10.1117/12.2001362  0.818
2012 Ma H, Gibson EA, Dittmer PJ, Dean K, Palmer AE, Jimenez R. Heterogeneity and Kinetics of FRET-Based Ca2+ and Zn2+ Sensors in HeLa Cells Biophysical Journal. 102: 209a. DOI: 10.1016/J.Bpj.2011.11.1139  0.772
2012 Lubbeck JL, Dean KM, Davis LM, Palmer AE, Jimenez R. Microfluidic Cytometer For Simultaneous High-Throughput Screening of Fluorescent Proteins on the Basis of Fluorescence Lifetime, Photostability, and Brightness Biophysical Journal. 102: 208a-209a. DOI: 10.1016/J.Bpj.2011.11.1138  0.818
2011 Dean KM, Lubbeck JL, Binder JK, Schwall LR, Jimenez R, Palmer AE. Analysis of red-fluorescent proteins provides insight into dark-state conversion and photodegradation. Biophysical Journal. 101: 961-9. PMID 21843488 DOI: 10.1016/J.Bpj.2011.06.055  0.782
2011 Dean KM, Williamson JC. The stir-settle approach to semiautomated light scattering determination of liquid-liquid coexistence curves Journal of Chemical and Engineering Data. 56: 1433-1437. DOI: 10.1021/Je101143G  0.419
2011 Lubbeck JL, Dean KM, Davis LM, Palmer AE, Jimenez R. A Microfluidic Cell Sorter for Directed Evolution of Fluorescent Proteins Based on Dark-State Conversion and Photobleaching Biophysical Journal. 100: 175a. DOI: 10.1016/J.Bpj.2010.12.1176  0.825
2010 Dean KM, Babayco CB, Sluss DR, Williamson JC. The accuracy of liquid-liquid phase transition temperatures determined from semiautomated light scattering measurements. The Journal of Chemical Physics. 133: 074506. PMID 20726651 DOI: 10.1063/1.3469778  0.417
2010 Lubbeck JL, Dean KM, Jiminez R, Palmer AE. A Microfluidic Cytometer for High-Throughput and Quantitative Single Cell Red Fluorescent Protein Photobleaching Biophysical Journal. 98: 584a. DOI: 10.1016/J.Bpj.2009.12.3173  0.829
2009 Gibson EA, Dittmer PJ, Dean K, Jimenez R, Palmer AE. A Microfluidic Platform For High-Throughput Screening And Sorting Of Cells Based Upon FRET Response Biophysical Journal. 96: 544a-545a. DOI: 10.1016/J.Bpj.2008.12.2948  0.819
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