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Jamie E. Jennings-Gee, Ph.D. - Publications

Affiliations: 
2002 Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Biochemistry, Molecular Biology
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Gmeiner WH, Jennings-Gee J, Stuart CH, Pardee TS. Thymineless death in F10-treated AML cells occurs via lipid raft depletion and Fas/FasL co-localization in the plasma membrane with activation of the extrinsic apoptotic pathway Leukemia Research. 39: 229-235. PMID 25510486 DOI: 10.1016/J.Leukres.2014.11.006  0.393
2015 Gmeiner WH, Boyacioglu O, Stuart CH, Jennings-Gee J, Balaji KC. The cytotoxic and pro-apoptotic activities of the novel fluoropyrimidine F10 Towards prostate cancer cells are enhanced by Zn2+-chelation and inhibiting the serine protease Omi/HtrA2 Prostate. 75: 360-369. PMID 25408502 DOI: 10.1002/Pros.22922  0.338
2014 Pardee TS, Stadelman K, Jennings-Gee J, Caudell DL, Gmeiner WH. The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells. Oncotarget. 5: 4170-9. PMID 24961587 DOI: 10.18632/Oncotarget.1937  0.321
2014 Gmeiner WH, Lema-Tome C, Gibo D, Jennings-Gee J, Milligan C, Debinski W. Selective anti-tumor activity of the novel fluoropyrimidine polymer F10 towards G48a orthotopic GBM tumors. Journal of Neuro-Oncology. 116: 447-54. PMID 24346635 DOI: 10.1007/S11060-013-1321-1  0.301
2013 Jennings-Gee J, Pardee TS, Gmeiner WH. Replication-dependent irreversible topoisomerase 1 poisoning is responsible for FdUMP[10] anti-leukemic activity. Experimental Hematology. 41: 180-188.e4. PMID 23085462 DOI: 10.1016/J.Exphem.2012.10.007  0.441
2013 Pardee T, Jennings-Gee J, Stadelman K, Caudell DL, Gmeiner W. The Poison Oligonucleotide F10 Is Efficiently Taken Up By, and Highly Effective Against, Acute Lymphoblastic Leukemia While Sparing Normal Hematopoietic Cells Blood. 122: 2674-2674. DOI: 10.1182/Blood.V122.21.2674.2674  0.335
2012 Pardee TS, Gomes E, Jennings-Gee J, Caudell D, Gmeiner WH. Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity. Blood. 119: 3561-70. PMID 22362039 DOI: 10.1182/Blood-2011-06-362442  0.369
2012 Pardee T, Jennings-Gee J, Alexander P, Gmeiner W. Thymidylate Synthase Inhibition with the Novel Fluoropyrimidine FdUMP[10] Is Highly Effective Against Acute Lymphoblastic Leukemia Blood. 120: 1505-1505. DOI: 10.1182/Blood.V120.21.1505.1505  0.417
2010 Pardee T, Gomes E, Jennings-Gee J, Caudell DL, Gmeiner W. The Novel Fluoropyrimidine FdUMP[10] Is Highly Active Against Acute Myeloid Leukemia Blood. 116: 3302-3302. DOI: 10.1182/Blood.V116.21.3302.3302  0.374
2010 Gomes E, Jennings-Gee J, Gmeiner WH. Abstract 1637: The MEK/Erk pathway is required for PC3 cell survival following FdUMP[10] treatment Cancer Research. 70: 1637-1637. DOI: 10.1158/1538-7445.Am10-1637  0.329
2006 Jennings-Gee JE, Tsuji Y, Pietsch EC, Moran E, Mymryk JS, Torti FM, Torti SV. Coordinate inhibition of cytokine-mediated induction of ferritin H, manganese superoxide dismutase, and interleukin-6 by the adenovirus E1A oncogene. The Journal of Biological Chemistry. 281: 16428-35. PMID 16611629 DOI: 10.1074/Jbc.M600038200  0.526
2002 Greene BT, Thorburn J, Willingham MC, Thorburn A, Planalp RP, Brechbiel MW, Jennings-Gee J, Wilkinson J, Torti FM, Torti SV. Activation of caspase pathways during iron chelator-mediated apoptosis. The Journal of Biological Chemistry. 277: 25568-75. PMID 11980894 DOI: 10.1074/Jbc.M110345200  0.568
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