Elisabeth D. Martinez, Ph.D. - Publications

2002 Georgetown University Medical Center, Washington, DC, United States 
Molecular Biology, Biochemistry, Oncology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Martinez ED, Gazdar AF. Inhibiting the Jumonji family: a potential new clinical approach to targeting aberrant epigenetic mechanisms. Epigenomics. 8: 313-6. PMID 26918824 DOI: 10.2217/epi.15.115  1
2015 Wang L, Kofler M, Brosch G, Melesina J, Sippl W, Martinez ED, Easmon J. 2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity. Plos One. 10: e0134556. PMID 26698121 DOI: 10.1371/journal.pone.0134556  1
2015 Trošt N, Peña-Llopis S, Koirala S, Stojan J, Potts PR, Tacer KF, Martinez ED. γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers. Oncotarget. PMID 26556877 DOI: 10.18632/oncotarget.6006  1
2015 Bayo J, Dalvi MP, Martinez ED. Successful strategies in the discovery of small-molecule epigenetic modulators with anticancer potential. Future Medicinal Chemistry. PMID 26510529 DOI: 10.4155/fmc.15.140  1
2015 Duan L, Rai G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chemistry & Biology. PMID 26364928 DOI: 10.1016/j.chembiol.2015.08.007  1
2015 Thinnes CC, Tumber A, Yapp C, Scozzafava G, Yeh T, Chan MC, Tran TA, Hsu K, Tarhonskaya H, Walport LJ, Wilkins SE, Martinez ED, Müller S, Pugh CW, Ratcliffe PJ, et al. Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chemical Communications (Cambridge, England). 51: 15458-61. PMID 26345662 DOI: 10.1039/c5cc06095h  1
2015 Huffman KE, Carstens R, Martinez ED. A Subset of Nuclear Receptors are Uniquely Expressed in Uveal Melanoma Cells. Frontiers in Endocrinology. 6: 93. PMID 26217306 DOI: 10.3389/fendo.2015.00093  1
2015 Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, ... ... Martinez ED, et al. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. The Journal of Clinical Investigation. 125: 1147-62. PMID 25664850 DOI: 10.1172/JCI74725  1
2014 Tran TA, Wichterman-Kouznetsova J, Varghese D, Huang R, Huang W, Becker M, Austin CP, Inglese J, Johnson RL, Martinez ED. Identification of small molecule modulators of gene transcription with anticancer activity. Acs Chemical Biology. 9: 2603-11. PMID 25188650 DOI: 10.1021/cb500532x  1
2013 Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, ... ... Martinez ED, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nature Communications. 4: 2035. PMID 23792809 DOI: 10.1038/ncomms3035  1
2013 Huffman K, Martinez ED. Pre-clinical studies of epigenetic therapies targeting histone modifiers in lung cancer Frontiers in Oncology. 3. DOI: 10.3389/fonc.2013.00235  1
2012 Hu Y, Martinez ED, MacMillan JB. Anthraquinones from a marine-derived streptomyces spinoverrucosus Journal of Natural Products. 75: 1759-1764. PMID 23057874 DOI: 10.1021/np3004326  1
2012 Chang J, Varghese DS, Gillam MC, Peyton M, Modi B, Schiltz RL, Girard L, Martinez ED. Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide. British Journal of Cancer. 106: 116-25. PMID 22158273 DOI: 10.1038/bjc.2011.532  1
2011 Best AM, Chang J, Dull AB, Beutler JA, Martinez ED. Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay. Journal of Biomedicine & Biotechnology. 2011: 868095. PMID 21234371 DOI: 10.1155/2011/868095  1
2010 Holbeck S, Chang J, Best AM, Bookout AL, Mangelsdorf DJ, Martinez ED. Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions. Molecular Endocrinology (Baltimore, Md.). 24: 1287-96. PMID 20375240 DOI: 10.1210/me.2010-0040  1
2008 Slack MD, Martinez ED, Wu LF, Altschuler SJ. Characterizing heterogeneous cellular responses to perturbations. Proceedings of the National Academy of Sciences of the United States of America. 105: 19306-11. PMID 19052231 DOI: 10.1073/pnas.0807038105  1
2008 Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression. Analytical Biochemistry. 375: 237-48. PMID 18211814 DOI: 10.1016/j.ab.2007.12.028  1
2007 Martinez ED, Botos J, Dohoney KM, Geiman TM, Kolla SS, Olivera A, Qiu Y, Rayasam GV, Stavreva DA, Cohen-Fix O. Falling off the academic bandwagon. Women are more likely to quit at the postdoc to principal investigator transition. Embo Reports. 8: 977-81. PMID 17972894 DOI: 10.1038/sj.embor.7401110  1
2006 Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format. Methods in Enzymology. 414: 566-89. PMID 17110211 DOI: 10.1016/S0076-6879(06)14029-X  1
2006 Martinez ED, Hager GL. Development of assays for nuclear receptor modulators using fluorescently tagged proteins. Methods in Enzymology. 414: 37-50. PMID 17110185 DOI: 10.1016/S0076-6879(06)14003-3  1
2006 Martinez ED, Dull AB, Beutler JA, Hager GL. High-content fluorescence-based screening for epigenetic modulators. Methods in Enzymology. 414: 21-36. PMID 17110184 DOI: 10.1016/S0076-6879(06)14002-1  1
2006 Qiu Y, Zhao Y, Becker M, John S, Parekh BS, Huang S, Hendarwanto A, Martinez ED, Chen Y, Lu H, Adkins NL, Stavreva DA, Wiench M, Georgel PT, Schiltz RL, et al. HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription. Molecular Cell. 22: 669-79. PMID 16762839 DOI: 10.1016/j.molcel.2006.04.019  1
2005 Martinez ED, Rayasam GV, Dull AB, Walker DA, Hager GL. An estrogen receptor chimera senses ligands by nuclear translocation. The Journal of Steroid Biochemistry and Molecular Biology. 97: 307-21. PMID 16162406 DOI: 10.1016/j.jsbmb.2005.06.033  1
2005 Martinez ED, Pattabiraman N, Danielsen M. Analysis of the hormone-binding domain of steroid receptors using chimeras generated by homologous recombination. Experimental Cell Research. 308: 320-33. PMID 15936754 DOI: 10.1016/j.yexcr.2005.03.040  1
2004 Nagaich AK, Rayasam GV, Martinez ED, Becker M, Qiu Y, Johnson TA, Elbi C, Fletcher TM, John S, Hager GL. Subnuclear trafficking and gene targeting by steroid receptors. Annals of the New York Academy of Sciences. 1024: 213-20. PMID 15265783 DOI: 10.1196/annals.1321.002  1
2003 Tirado OM, Martinez ED, Rodriguez OC, Danielsen M, Selva DM, Reventós J, Munell F, Suárez-Quian CA. Methoxyacetic acid disregulation of androgen receptor and androgen-binding protein expression in adult rat testis. Biology of Reproduction. 68: 1437-46. PMID 12606434 DOI: 10.1095/biolreprod.102.004937  1
2002 Martinez ED, Danielsen M. Loss of androgen receptor transcriptional activity at the G(1)/S transition. The Journal of Biological Chemistry. 277: 29719-29. PMID 12055183 DOI: 10.1074/jbc.M112134200  1
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