Patrick J. Sinko - Publications

Affiliations: 
Rutgers University, New Brunswick, United States 
Area:
Pharmacy, Pharmaceutical Chemistry, Animal Physiology Biology
Website:
https://pharmacy.rutgers.edu/directory/sinko-patrick/

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Gu Z, Al-Zubaydi F, Adler D, Li S, Johnson S, Prasad P, Holloway J, Szekely Z, Love S, Gao D, Sinko PJ. Evaluation of intraductal delivery of poly(ethylene glycol)-doxorubicin conjugate nanocarriers for the treatment of ductal carcinoma in situ (DCIS)-like lesions in rats. Journal of Interdisciplinary Nanomedicine. 3: 146-159. PMID 30443411 DOI: 10.1002/jin2.51  0.64
2018 Heon Lee I, Palombo MS, Zhang X, Szekely Z, Sinko PJ. Design and Evaluation of a CXCR4 Targeting Peptide 4DV3 as an HIV Entry Inhibitor and a Ligand for Targeted Drug Delivery. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29894816 DOI: 10.1016/j.ejpb.2018.06.004  0.8
2018 Gu Z, Gao D, Al-Zubaydi F, Li S, Singh Y, Rivera K, Holloway J, Szekely Z, Love S, Sinko PJ. The effect of size and polymer architecture of doxorubicin-poly(ethylene) glycol conjugate nanocarriers on breast duct retention, potency and toxicity. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29698706 DOI: 10.1016/j.ejps.2018.04.033  0.64
2016 Dong H, Ma J, Wang J, Wu ZS, Sinko PJ, Jia L. A Biofunctional Molecular Beacon for Detecting Single Base Mutations in Cancer Cells. Molecular Therapy. Nucleic Acids. 5: e302. PMID 27045206 DOI: 10.1038/mtna.2016.18  1
2016 Gao Y, Gu S, Zhang Y, Xie X, Yu T, Lu Y, Zhu Y, Chen W, Zhang H, Dong H, Sinko PJ, Jia L. The Architecture and Function of Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles Loaded with Mifepristone: Repurposing Abortifacient for Cancer Metastatic Chemoprevention. Small (Weinheim An Der Bergstrasse, Germany). PMID 27027489 DOI: 10.1002/smll.201600550  1
2015 Samizadeh M, Zhang X, Gunaseelan S, Nelson AG, Palombo MS, Myers DR, Singh Y, Ganapathi U, Szekely Z, Sinko PJ. Colorectal delivery and retention of PEG-Amprenavir-Bac7 nanoconjugates-proof of concept for HIV mucosal pre-exposure prophylaxis. Drug Delivery and Translational Research. PMID 26712122 DOI: 10.1007/s13346-015-0269-4  1
2015 Gao Y, Jin B, Shen W, Sinko P, Xie X, Zhang H, Jia L. China and the United States- global partners, competitors and collaborators in nanotechnology development. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26427355 DOI: 10.1016/j.nano.2015.09.007  1
2015 Nelson AG, Zhang X, Ganapathi U, Szekely Z, Flexner CW, Owen A, Sinko PJ. Drug delivery strategies and systems for HIV/AIDS pre-exposure prophylaxis and treatment. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26315816 DOI: 10.1016/j.jconrel.2015.08.042  1
2015 Tang C, Xiao E, Sinko PJ, Szekely Z, Prud'homme RK. Responsive foams for nanoparticle delivery. Colloids and Surfaces. B, Biointerfaces. 133: 81-7. PMID 26091943 DOI: 10.1016/j.colsurfb.2015.05.038  1
2015 Lu Y, Liang H, Yu T, Xie J, Chen S, Dong H, Sinko PJ, Lian S, Xu J, Wang J, Yu S, Shao J, Yuan B, Wang L, Jia L. Isolation and characterization of living circulating tumor cells in patients by immunomagnetic negative enrichment coupled with flow cytometry. Cancer. 121: 3036-45. PMID 25945459 DOI: 10.1002/cncr.29444  1
2015 Xie J, Gao Y, Zhao R, Sinko PJ, Gu S, Wang J, Li Y, Lu Y, Yu S, Wang L, Chen S, Shao J, Jia L. Ex vivo and in vivo capture and deactivation of circulating tumor cells by dual-antibody-coated nanomaterials. Journal of Controlled Release : Official Journal of the Controlled Release Society. 209: 159-69. PMID 25933713 DOI: 10.1016/j.jconrel.2015.04.036  1
2015 Pinkerton NM, Gindy ME, Calero-DdelC VL, Wolfson T, Pagels RF, Adler D, Gao D, Li S, Wang R, Zevon M, Yao N, Pacheco C, Therien MJ, Rinaldi C, Sinko PJ, et al. Single-Step Assembly of Multimodal Imaging Nanocarriers: MRI and Long-Wavelength Fluorescence Imaging. Advanced Healthcare Materials. 4: 1376-85. PMID 25925128 DOI: 10.1002/adhm.201400766  1
2015 Xie J, Wang J, Chen H, Shen W, Sinko PJ, Dong H, Zhao R, Lu Y, Zhu Y, Jia L. Multivalent conjugation of antibody to dendrimers for the enhanced capture and regulation on colon cancer cells. Scientific Reports. 5: 9445. PMID 25819426 DOI: 10.1038/srep09445  1
2015 D'Addio SM, Reddy VM, Liu Y, Sinko PJ, Einck L, Prud'homme RK. Antitubercular Nanocarrier Combination Therapy: Formulation Strategies and in Vitro Efficacy for Rifampicin and SQ641. Molecular Pharmaceutics. 12: 1554-63. PMID 25811733 DOI: 10.1021/mp5008663  1
2015 Xie J, Dong H, Chen H, Zhao R, Sinko PJ, Shen W, Wang J, Lu Y, Yang X, Xie F, Jia L. Exploring cancer metastasis prevention strategy: interrupting adhesion of cancer cells to vascular endothelia of potential metastatic tissues by antibody-coated nanomaterial. Journal of Nanobiotechnology. 13: 9. PMID 25643843 DOI: 10.1186/s12951-015-0072-x  1
2015 Yu S, Yang X, Zhu Y, Xie F, Lu Y, Yu T, Yan C, Shao J, Gao Y, Mo F, Cai G, Sinko PJ, Jia L. Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex. Scientific Reports. 5: 7830. PMID 25597938 DOI: 10.1038/srep07830  1
2015 Dong H, Gao Y, Sinko PJ, Wu Z, Xu J, Jia L. The nanotechnology race between China and the United States Nano Today. DOI: 10.1016/j.nantod.2016.02.001  1
2015 Xie J, Lu Y, Dong H, Zhao R, Chen H, Shen W, Sinko PJ, Zhu Y, Wang J, Shao J, Gao Y, Xie F, Jia L. Enhanced specificity in capturing and restraining circulating tumor cells with dual antibody-dendrimer conjugates Advanced Functional Materials. 25: 1304-1313. DOI: 10.1002/adfm.201403556  1
2014 Xie J, Zhao R, Gu S, Dong H, Wang J, Lu Y, Sinko PJ, Yu T, Xie F, Wang L, Shao J, Jia L. The architecture and biological function of dual antibody-coated dendrimers: enhanced control of circulating tumor cells and their hetero-adhesion to endothelial cells for metastasis prevention. Theranostics. 4: 1250-63. PMID 25285173 DOI: 10.7150/thno.8775  1
2014 Sundara Rajan S, Turovskiy Y, Singh Y, Chikindas ML, Sinko PJ. Poly(ethylene glycol) (PEG)-lactic acid nanocarrier-based degradable hydrogels for restoring the vaginal microenvironment. Journal of Controlled Release : Official Journal of the Controlled Release Society. 194: 301-9. PMID 25223229 DOI: 10.1016/j.jconrel.2014.08.031  1
2014 Chen P, Zhang X, Jia L, Prud'homme RK, Szekely Z, Sinko PJ. Optimal structural design of mannosylated nanocarriers for macrophage targeting. Journal of Controlled Release : Official Journal of the Controlled Release Society. 194: 341-9. PMID 25220160 DOI: 10.1016/j.jconrel.2014.09.006  1
2014 Chang YC, Wang JD, Hahn RA, Gordon MK, Joseph LB, Heck DE, Heindel ND, Young SC, Sinko PJ, Casillas RP, Laskin JD, Laskin DL, Gerecke DR. Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard. Toxicology and Applied Pharmacology. 280: 236-44. PMID 25127551 DOI: 10.1016/j.taap.2014.07.016  1
2014 Joseph LB, Heck DE, Cervelli JA, Composto GM, Babin MC, Casillas RP, Sinko PJ, Gerecke DR, Laskin DL, Laskin JD. Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard. Experimental and Molecular Pathology. 96: 316-27. PMID 24662110 DOI: 10.1016/j.yexmp.2014.03.002  1
2014 Sundara Rajan S, Cavera VL, Zhang X, Singh Y, Chikindas ML, Sinko PJ. Polyethylene glycol-based hydrogels for controlled release of the antimicrobial subtilosin for prophylaxis of bacterial vaginosis. Antimicrobial Agents and Chemotherapy. 58: 2747-53. PMID 24566190 DOI: 10.1128/AAC.02446-14  1
2014 Pinkerton NM, Zhang SW, Youngblood RL, Gao D, Li S, Benson BR, Anthony J, Stone HA, Sinko PJ, Prud'homme RK. Gelation chemistries for the encapsulation of nanoparticles in composite gel microparticles for lung imaging and drug delivery. Biomacromolecules. 15: 252-61. PMID 24410445 DOI: 10.1021/bm4015232  1
2014 Palombo M, Deshmukh M, Myers D, Gao J, Szekely Z, Sinko PJ. Pharmaceutical and toxicological properties of engineered nanomaterials for drug delivery. Annual Review of Pharmacology and Toxicology. 54: 581-98. PMID 24160695 DOI: 10.1146/annurev-pharmtox-010611-134615  1
2014 Ibrahim S, Gao D, Sinko PJ. Selective cytotoxicity and combined effects of camptothecin or paclitaxel with sodium-R-alpha lipoate on A549 human non-small cell lung cancer cells. Nutrition and Cancer. 66: 492-9. PMID 24063429 DOI: 10.1080/01635581.2013.749290  1
2014 Liu D, Zhang X, Gao J, Palombo M, Gao D, Chen P, Sinko PJ. Core functional sequence of C-terminal GAG-binding domain directs cellular uptake of IGFBP-3-derived peptides. Protein and Peptide Letters. 21: 124-31. PMID 24059751  1
2014 Quintana VM, Torres NI, Wachsman MB, Sinko PJ, Castilla V, Chikindas M. Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin Journal of Applied Microbiology. DOI: 10.1111/jam.12618  1
2014 Sinko PJ. Drug Transporters in the Intestine Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 327-339. DOI: 10.1002/9781118705308.ch16  1
2013 Torres NI, Sutyak Noll K, Xu S, Li J, Huang Q, Sinko PJ, Wachsman MB, Chikindas ML. Erratum to: Safety, Formulation and In Vitro Antiviral Activity of the Antimicrobial Peptide Subtilosin Against Herpes Simplex Virus Type 1. Probiotics and Antimicrobial Proteins. 5: 36. PMID 26782602 DOI: 10.1007/s12602-013-9128-0  0.32
2013 Zheng R, Po I, Mishin V, Black AT, Heck DE, Laskin DL, Sinko PJ, Gerecke DR, Gordon MK, Laskin JD. The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard. Toxicology and Applied Pharmacology. 272: 345-55. PMID 23845594 DOI: 10.1016/j.taap.2013.06.025  1
2013 Gao J, Chen P, Singh Y, Zhang X, Szekely Z, Stein S, Sinko PJ. Novel monodisperse PEGtide dendrons: design, fabrication, and evaluation of mannose receptor-mediated macrophage targeting. Bioconjugate Chemistry. 24: 1332-44. PMID 23808323 DOI: 10.1021/bc400011v  1
2013 Torres NI, Noll KS, Xu S, Li J, Huang Q, Sinko PJ, Wachsman MB, Chikindas ML. Safety, formulation, and in vitro antiviral activity of the antimicrobial peptide subtilosin against herpes simplex virus type 1. Probiotics and Antimicrobial Proteins. 5: 26-35. PMID 23637711 DOI: 10.1007/s12602-012-9123-x  1
2013 D'Addio SM, Baldassano S, Shi L, Cheung L, Adamson DH, Bruzek M, Anthony JE, Laskin DL, Sinko PJ, Prud'homme RK. Optimization of cell receptor-specific targeting through multivalent surface decoration of polymeric nanocarriers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 168: 41-9. PMID 23419950 DOI: 10.1016/j.jconrel.2013.02.004  1
2013 Kutscher HL, Gao D, Li S, Massa CB, Cervelli J, Deshmukh M, Joseph LB, Laskin DL, Sinko PJ. Toxicodynamics of rigid polystyrene microparticles on pulmonary gas exchange in mice: implications for microemboli-based drug delivery systems. Toxicology and Applied Pharmacology. 266: 214-23. PMID 23142466 DOI: 10.1016/j.taap.2012.10.021  1
2013 Sinko PJ. Diffusion Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences: Sixth Edition. 223-257.  1
2013 Sinko PJ. Biopharmaceutics Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences: Sixth Edition. 258-299.  1
2013 Sinko PJ. Drug release and dissolution Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences: Sixth Edition. 300-317.  1
2013 Sinko PJ, Singh Y. Martin's physical pharmacy and pharmaceutical sciences: Physical chemical and biopharmaceutical principles in the pharmaceutical sciences: Sixth edition Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences: Sixth Edition. 1-659.  1
2013 Omidian H, Park K, Sinko PJ. Pharmaceutical polymers Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences: Sixth Edition. 492-515.  0.4
2013 Singh Y, Omidian H, Sinko PJ. Drug delivery and targeting Martin's Physical Pharmacy and Pharmaceutical Sciences: Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences: Sixth Edition. 594-646.  1
2013 Khoury GA, Tamamis P, Smadbeck J, Szekely Z, Sinko PJ, Floudas CA. Understanding the antagonistic mechanism of a de novo designed peptide with experimental HIV fusion inhibition via molecular simulation Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 45-46.  1
2012 Deshmukh M, Kutscher HL, Gao D, Sunil VR, Malaviya R, Vayas K, Stein S, Laskin JD, Laskin DL, Sinko PJ. Biodistribution and renal clearance of biocompatible lung targeted poly(ethylene glycol) (PEG) nanogel aggregates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 65-73. PMID 23041417 DOI: 10.1016/j.jconrel.2012.09.011  1
2012 Turovskiy Y, Cheryian T, Algburi A, Wirawan RE, Takhistov P, Sinko PJ, Chikindas ML. Susceptibility of Gardnerella vaginalis biofilms to natural antimicrobials subtilosin, ε-poly-L-lysine, and lauramide arginine ethyl ester. Infectious Diseases in Obstetrics and Gynecology. 2012: 284762. PMID 23024575 DOI: 10.1155/2012/284762  1
2012 Malaviya R, Venosa A, Hall L, Gow AJ, Sinko PJ, Laskin JD, Laskin DL. Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor. Toxicology and Applied Pharmacology. 265: 279-91. PMID 22981630 DOI: 10.1016/j.taap.2012.08.027  1
2012 Wan J, Shi L, Benson B, Bruzek MJ, Anthony JE, Sinko PJ, Prudhomme RK, Stone HA. Microfluidic generation of droplets with a high loading of nanoparticles. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 13143-8. PMID 22934976 DOI: 10.1021/la3025952  1
2012 Singh Y, Gao D, Gu Z, Li S, Rivera KA, Stein S, Love S, Sinko PJ. Influence of molecular size on the retention of polymeric nanocarrier diagnostic agents in breast ducts. Pharmaceutical Research. 29: 2377-88. PMID 22569800 DOI: 10.1007/s11095-012-0763-z  1
2012 Noll KS, Prichard MN, Khaykin A, Sinko PJ, Chikindas ML. The natural antimicrobial peptide subtilosin acts synergistically with glycerol monolaurate, lauric arginate, and ε-poly-L-lysine against bacterial vaginosis-associated pathogens but not human lactobacilli. Antimicrobial Agents and Chemotherapy. 56: 1756-61. PMID 22252803 DOI: 10.1128/AAC.05861-11  1
2012 Singh Y, Gao D, Gu Z, Li S, Stein S, Sinko PJ. Noninvasive detection of passively targeted poly(ethylene glycol) nanocarriers in tumors. Molecular Pharmaceutics. 9: 144-55. PMID 22077582 DOI: 10.1021/mp2003913  1
2012 Cui H, Sinko PJ. The role of crystallinity on differential attachment/proliferation of osteoblasts and fibroblasts on poly (caprolactone-co-glycolide) polymeric surfaces Frontiers of Materials Science. 6: 47-59. DOI: 10.1007/s11706-012-0154-8  1
2011 Noll KS, Sinko PJ, Chikindas ML. Elucidation of the Molecular Mechanisms of Action of the Natural Antimicrobial Peptide Subtilosin Against the Bacterial Vaginosis-associated Pathogen Gardnerella vaginalis. Probiotics and Antimicrobial Proteins. 3: 41-47. PMID 21949544 DOI: 10.1007/s12602-010-9061-4  1
2011 Joseph LB, Gerecke DR, Heck DE, Black AT, Sinko PJ, Cervelli JA, Casillas RP, Babin MC, Laskin DL, Laskin JD. Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage. Experimental and Molecular Pathology. 91: 515-27. PMID 21672537 DOI: 10.1016/j.yexmp.2011.05.010  1
2011 Cai CY, Zhang X, Sinko PJ, Burakoff SJ, Jin YJ. Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis. Journal of Immunology (Baltimore, Md. : 1950). 186: 5807-14. PMID 21482738 DOI: 10.4049/jimmunol.1003506  1
2011 Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD. Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 253: 112-20. PMID 21457723 DOI: 10.1016/j.taap.2011.03.015  1
2011 Anumolu SS, Menjoge AR, Deshmukh M, Gerecke D, Stein S, Laskin J, Sinko PJ. Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries. Biomaterials. 32: 1204-17. PMID 20950853 DOI: 10.1016/j.biomaterials.2010.08.117  1
2011 Weinberger B, Laskin JD, Sunil VR, Sinko PJ, Heck DE, Laskin DL. Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity. Pulmonary Pharmacology & Therapeutics. 24: 92-9. PMID 20851203 DOI: 10.1016/j.pupt.2010.09.004  1
2010 Gordon MK, Desantis A, Deshmukh M, Lacey CJ, Hahn RA, Beloni J, Anumolu SS, Schlager JJ, Gallo MA, Gerecke DR, Heindel ND, Svoboda KK, Babin MC, Sinko PJ. Doxycycline hydrogels as a potential therapy for ocular vesicant injury. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 26: 407-19. PMID 20925577 DOI: 10.1089/jop.2010.0099  1
2010 Kutscher HL, Chao P, Deshmukh M, Sundara Rajan S, Singh Y, Hu P, Joseph LB, Stein S, Laskin DL, Sinko PJ. Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats. International Journal of Pharmaceutics. 402: 64-71. PMID 20883756 DOI: 10.1016/j.ijpharm.2010.09.020  1
2010 Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD. Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 249: 178-87. PMID 20840853 DOI: 10.1016/j.taap.2010.09.005  1
2010 Laskin JD, Black AT, Jan YH, Sinko PJ, Heindel ND, Sunil V, Heck DE, Laskin DL. Oxidants and antioxidants in sulfur mustard-induced injury. Annals of the New York Academy of Sciences. 1203: 92-100. PMID 20716289 DOI: 10.1111/j.1749-6632.2010.05605.x  1
2010 Deshmukh M, Singh Y, Gunaseelan S, Gao D, Stein S, Sinko PJ. Biodegradable poly(ethylene glycol) hydrogels based on a self-elimination degradation mechanism. Biomaterials. 31: 6675-84. PMID 20561680 DOI: 10.1016/j.biomaterials.2010.05.021  1
2010 Black AT, Joseph LB, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD. Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 245: 352-60. PMID 20382172 DOI: 10.1016/j.taap.2010.04.001  1
2010 Deshmukh M, Chao P, Kutscher HL, Gao D, Sinko PJ. A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity. Journal of Medicinal Chemistry. 53: 1038-47. PMID 20063889 DOI: 10.1021/jm901029n  1
2010 Kutscher HL, Chao P, Deshmukh M, Singh Y, Hu P, Joseph LB, Reimer DC, Stein S, Laskin DL, Sinko PJ. Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. 143: 31-7. PMID 20043961 DOI: 10.1016/j.jconrel.2009.12.019  1
2010 Chao P, Deshmukh M, Kutscher HL, Gao D, Rajan SS, Hu P, Laskin DL, Stein S, Sinko PJ. Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model. Anti-Cancer Drugs. 21: 65-76. PMID 19966540 DOI: 10.1097/CAD.0b013e328332a322  1
2010 Gunaseelan S, Gunaseelan K, Deshmukh M, Zhang X, Sinko PJ. Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs. Advanced Drug Delivery Reviews. 62: 518-31. PMID 19941919 DOI: 10.1016/j.addr.2009.11.021  1
2010 Anumolu SS, DeSantis AS, Menjoge AR, Hahn RA, Beloni JA, Gordon MK, Sinko PJ. Doxycycline loaded poly(ethylene glycol) hydrogels for healing vesicant-induced ocular wounds. Biomaterials. 31: 964-74. PMID 19853296 DOI: 10.1016/j.biomaterials.2009.10.010  1
2010 Shakarjian MP, Heck DE, Gray JP, Sinko PJ, Gordon MK, Casillas RP, Heindel ND, Gerecke DR, Laskin DL, Laskin JD. Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 5-19. PMID 19833738 DOI: 10.1093/toxsci/kfp253  1
2009 Gunaseelan S, Pooyan S, Chen P, Samizadeh M, Palombo MS, Stein S, Zhang X, Sinko PJ. Multimeric peptide-based PEG nanocarriers with programmable elimination properties. Biomaterials. 30: 5649-59. PMID 19647312 DOI: 10.1016/j.biomaterials.2009.05.068  1
2009 Anumolu SS, Singh Y, Gao D, Stein S, Sinko PJ. Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response. Journal of Controlled Release : Official Journal of the Controlled Release Society. 137: 152-9. PMID 19341773 DOI: 10.1016/j.jconrel.2009.03.016  1
2009 Zhang X, Jin Y, Plummer MR, Pooyan S, Gunaseelan S, Sinko PJ. Endocytosis and membrane potential are required for HeLa cell uptake of R.I.-CKTat9, a retro-inverso Tat cell penetrating peptide. Molecular Pharmaceutics. 6: 836-48. PMID 19278221 DOI: 10.1021/mp800121f  1
2009 Palombo MS, Singh Y, Sinko PJ. Prodrug and conjugate drug delivery strategies for improving HIV/AIDS therapy Journal of Drug Delivery Science and Technology. 19: 3-14.  1
2008 Singh Y, Palombo M, Sinko PJ. Recent trends in targeted anticancer prodrug and conjugate design. Current Medicinal Chemistry. 15: 1802-26. PMID 18691040 DOI: 10.2174/092986708785132997  1
2008 Usansky HH, Hu P, Sinko PJ. Differential roles of P-glycoprotein, multidrug resistance-associated protein 2, and CYP3A on saquinavir oral absorption in Sprague-Dawley rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 863-9. PMID 18256206 DOI: 10.1124/dmd.107.017483  1
2008 Vortherms AR, Doyle RP, Gao D, Debrah O, Sinko PJ. Synthesis, characterization, and in vitro assay of folic acid conjugates of 3'-azido-3'-deoxythymidine (AZT): toward targeted AZT based anticancer therapeutics. Nucleosides, Nucleotides & Nucleic Acids. 27: 173-85. PMID 18205071 DOI: 10.1080/15257770701795946  1
2008 Wan L, Zhang X, Pooyan S, Palombo MS, Leibowitz MJ, Stein S, Sinko PJ. Optimizing size and copy number for PEG-fMLF (N-formyl-methionyl-leucyl-phenylalanine) nanocarrier uptake by macrophages. Bioconjugate Chemistry. 19: 28-38. PMID 18092743 DOI: 10.1021/bc070066k  1
2007 Su Y, Hu P, Lee SH, Sinko PJ. Using novobiocin as a specific inhibitor of breast cancer resistant protein to assess the role of transporter in the absorption and disposition of topotecan. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, SociéTé Canadienne Des Sciences Pharmaceutiques. 10: 519-36. PMID 18261372  1
2007 Wan L, Pooyan S, Hu P, Leibowitz MJ, Stein S, Sinko PJ. Peritoneal macrophage uptake, pharmacokinetics and biodistribution of macrophage-targeted PEG-fMLF (N-formyl-methionyl-leucyl-phenylalanine) nanocarriers for improving HIV drug delivery. Pharmaceutical Research. 24: 2110-9. PMID 17701325 DOI: 10.1007/s11095-007-9402-5  1
2007 Su Y, Zhang X, Sinko PJ. Exploitation of drug-induced Bcl-2 overexpression for restoring normal apoptosis function: a promising new approach to the treatment of multidrug resistant cancer. Cancer Letters. 253: 115-23. PMID 17349740 DOI: 10.1016/j.canlet.2007.01.018  1
2006 Su Y, Lee SH, Sinko PJ. Inhibition of efflux transporter ABCG2/BCRP does not restore mitoxantrone sensitivity in irinotecan-selected human leukemia CPT-K5 cells: evidence for multifactorial multidrug resistance. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 29: 102-10. PMID 16844360 DOI: 10.1016/j.ejps.2006.06.001  1
2006 Lalloo A, Chao P, Hu P, Stein S, Sinko PJ. Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins. Journal of Controlled Release : Official Journal of the Controlled Release Society. 112: 333-42. PMID 16650910 DOI: 10.1016/j.jconrel.2006.03.002  1
2006 Su Y, Sinko PJ. Drug delivery across the blood-brain barrier: why is it difficult? how to measure and improve it? Expert Opinion On Drug Delivery. 3: 419-35. PMID 16640501 DOI: 10.1517/17425247.3.3.419  1
2006 Wan L, Zhang X, Gunaseelan S, Pooyan S, Debrah O, Leibowitz MJ, Rabson AB, Stein S, Sinko PJ. Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects. Aids Research and Therapy. 3: 12. PMID 16635263 DOI: 10.1186/1742-6405-3-12  1
2006 Lee SH, Sinko PJ. siRNA--getting the message out. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 401-10. PMID 16442784 DOI: 10.1016/j.ejps.2005.12.002  1
2005 Dharap SS, Wang Y, Chandna P, Khandare JJ, Qiu B, Gunaseelan S, Sinko PJ, Stein S, Farmanfarmaian A, Minko T. Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide Proceedings of the National Academy of Sciences of the United States of America. 102: 12962-12967. PMID 16123131 DOI: 10.1073/pnas.0504274102  1
2005 Park S, Sinko PJ. The blood-brain barrier sodium-dependent multivitamin transporter: a molecular functional in vitro-in situ correlation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1547-54. PMID 16033951 DOI: 10.1124/dmd.105.005231  1
2005 Paranjpe PV, Stein S, Sinko PJ. Tumor-targeted and activated bioconjugates for improved camptothecin delivery. Anti-Cancer Drugs. 16: 763-75. PMID 16027527 DOI: 10.1097/01.cad.0000172834.78068.7c  1
2005 Lee KJ, Johnson N, Castelo J, Sinko PJ, Grass G, Holme K, Lee YH. Effect of experimental pH on the in vitro permeability in intact rabbit intestines and Caco-2 monolayer. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 25: 193-200. PMID 15911214 DOI: 10.1016/j.ejps.2005.02.012  1
2005 Bhardwaj RK, Herrera-Ruiz D, Sinko PJ, Gudmundsson OS, Knipp G. Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells. The Journal of Pharmacology and Experimental Therapeutics. 314: 1093-100. PMID 15901802 DOI: 10.1124/jpet.105.087148  1
2005 Usansky HH, Sinko PJ. Estimating human drug oral absorption kinetics from Caco-2 permeability using an absorption-disposition model: model development and evaluation and derivation of analytical solutions for k(a) and F(a). The Journal of Pharmacology and Experimental Therapeutics. 314: 391-9. PMID 15833900 DOI: 10.1124/jpet.104.076182  1
2005 Zhou F, Xu W, Hong M, Pan Z, Sinko PJ, Ma J, You G. The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4. Molecular Pharmacology. 67: 868-76. PMID 15576633 DOI: 10.1124/mol.104.007583  1
2005 Park S, Sinko PJ. P-glycoprotein and mutlidrug resistance-associated proteins limit the brain uptake of saquinavir in mice. The Journal of Pharmacology and Experimental Therapeutics. 312: 1249-56. PMID 15528451 DOI: 10.1124/jpet.104.076216  1
2004 Zhang X, Wan L, Pooyan S, Su Y, Gardner CR, Leibowitz MJ, Stein S, Sinko PJ. Quantitative assessment of the cell penetrating properties of RI-Tat-9: evidence for a cell type-specific barrier at the plasma membrane of epithelial cells. Molecular Pharmaceutics. 1: 145-55. PMID 15832511  1
2004 Su Y, Zhang X, Sinko PJ. Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells. Molecular Pharmaceutics. 1: 49-56. PMID 15832500  1
2004 Gunaseelan S, Debrah O, Wan L, Leibowitz MJ, Rabson AB, Stein S, Sinko PJ. Synthesis of poly(ethylene glycol)-based saquinavir prodrug conjugates and assessment of release and anti-HIV-1 bioactivity using a novel protease inhibition assay. Bioconjugate Chemistry. 15: 1322-33. PMID 15546199 DOI: 10.1021/bc0498875  1
2004 Paranjpe PV, Chen Y, Kholodovych V, Welsh W, Stein S, Sinko PJ. Tumor-targeted bioconjugate based delivery of camptothecin: design, synthesis and in vitro evaluation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 100: 275-92. PMID 15544875 DOI: 10.1016/j.jconrel.2004.08.030  1
2004 Kunta JR, Lee SH, Perry BA, Lee YH, Sinko PJ. Differentiation of gut and hepatic first-pass loss of verapamil in intestinal and vascular access-ported (IVAP) rabbits. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1293-8. PMID 15304428 DOI: 10.1124/dmd.104.000752  1
2004 Su Y, Lee SH, Sinko PJ. Practical aspects of transporter model systems: a case study involving SQV. Drug Metabolism Reviews. 36: 377-89. PMID 15237860 DOI: 10.1081/DMR-120037570  1
2004 Lalloo AK, Luo FR, Guo A, Paranjpe PV, Lee SH, Vyas V, Rubin E, Sinko PJ. Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2). Bmc Medicine. 2: 16. PMID 15125776 DOI: 10.1186/1741-7015-2-16  1
2004 Sinko PJ, Kunta JR, Usansky HH, Perry BA. Differentiation of gut and hepatic first pass metabolism and secretion of saquinavir in ported rabbits. The Journal of Pharmacology and Experimental Therapeutics. 310: 359-66. PMID 15004217 DOI: 10.1124/jpet.103.064394  1
2004 Kunta JR, Sinko PJ. Intestinal drug transporters: in vivo function and clinical importance. Current Drug Metabolism. 5: 109-24. PMID 14965254 DOI: 10.2174/1389200043489144  1
2004 Zhang G, Qiu B, Perry BA, Georgopoulos DE, Leibowitz MJ, Sinko PJ, Stein S. Bioreversible disulfide linkage of thioamide compounds to thiol-poly(ethylene glycol): Application to UC781, an inhibitor of HIV-1 reverse transcriptase Journal of Applied Therapeutic Research. 4: 46-53.  1
2003 Hong J, Lambert JD, Lee SH, Sinko PJ, Yang CS. Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochemical and Biophysical Research Communications. 310: 222-7. PMID 14511674 DOI: 10.1016/j.bbrc.2003.09.007  1
2003 Williams GC, Knipp GT, Sinko PJ. The effect of cell culture conditions on saquinavir transport through, and interactions with, MDCKII cells overexpressing hMDR1. Journal of Pharmaceutical Sciences. 92: 1957-67. PMID 14502536 DOI: 10.1002/jps.10458  1
2003 Lee KJ, Mower R, Hollenbeck T, Castelo J, Johnson N, Gordon P, Sinko PJ, Holme K, Lee YH. Modulation of nonspecific binding in ultrafiltration protein binding studies. Pharmaceutical Research. 20: 1015-21. PMID 12880287 DOI: 10.1023/A:1024406221962  1
2003 Usansky HH, Sinko PJ. Computation of log BB values for compounds transported through carrier-mediated mechanisms using in vitro permeability data from brain microvessel endothelial cell (BMEC) monolayers. Pharmaceutical Research. 20: 390-6. PMID 12669958 DOI: 10.1023/A:1022647903205  1
2003 Zhang G, Leibowitz MJ, Sinko PJ, Stein S. Multiple-peptide conjugates for binding beta-amyloid plaques of Alzheimer's disease. Bioconjugate Chemistry. 14: 86-92. PMID 12526697 DOI: 10.1021/bc025526i  1
2003 Qiu B, Stefanos S, Ma J, Lalloo A, Perry BA, Leibowitz MJ, Sinko PJ, Stein S. A hydrogel prepared by in situ cross-linking of a thiol-containing poly(ethylene glycol)-based copolymer: a new biomaterial for protein drug delivery. Biomaterials. 24: 11-8. PMID 12417173 DOI: 10.1016/S0142-9612(02)00227-2  1
2002 Williams GC, Liu A, Knipp G, Sinko PJ. Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2). Antimicrobial Agents and Chemotherapy. 46: 3456-62. PMID 12384350 DOI: 10.1128/AAC.46.11.3456-3462.2002  1
2002 Minko T, Paranjpe PV, Qiu B, Lalloo A, Won R, Stein S, Sinko PJ. Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethylene glycol) conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells. Cancer Chemotherapy and Pharmacology. 50: 143-50. PMID 12172980 DOI: 10.1007/s00280-002-0463-1  1
2002 Grass GM, Sinko PJ. Physiologically-based pharmacokinetic simulation modelling. Advanced Drug Delivery Reviews. 54: 433-51. PMID 11922957 DOI: 10.1016/S0169-409X(02)00013-3  1
2002 Pooyan S, Qiu B, Chan MM, Fong D, Sinko PJ, Leibowitz MJ, Stein S. Conjugates bearing multiple formyl-methionyl peptides display enhanced binding to but not activation of phagocytic cells. Bioconjugate Chemistry. 13: 216-23. PMID 11906258 DOI: 10.1021/bc0100657  1
2002 Guo A, Marinaro W, Hu P, Sinko PJ. Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 457-63. PMID 11901101 DOI: 10.1124/dmd.30.4.457  1
2002 Paranjpe PV, Sinko PJ. Overcoming paracellular tissue barriers for drug delivery Pharmaceutical News. 9: 381-395.  1
2001 Kunta JR, Perry BA, Sutyak JP, Sinko PJ. Development of a novel intestinal and vascular access port (IVAP) rabbit model to study regiospecific oral absorption pharmacokinetics. Comparative Medicine. 51: 349-56. PMID 11924794  1
2001 Lee YH, Perry BA, Lee HS, Kunta JR, Sutyak JP, Sinko PJ. Differentiation of gut and hepatic first-pass effect of drugs: 1. Studies of verapamil in ported dogs. Pharmaceutical Research. 18: 1721-8. PMID 11785692 DOI: 10.1023/A:1013374630274  1
2001 Hoffmann MJ, Sinko PJ, Meeker RJ, Snyder R. Pharmacokinetics of benzene following an oral or intradermal dose in FVB and Tg.AC mice Advances in Experimental Medicine and Biology. 500: 455-458. PMID 11764980  1
2001 Ramanathan S, Qiu B, Pooyan S, Zhang G, Stein S, Leibowitz MJ, Sinko PJ. Targeted PEG-based bioconjugates enhance the cellular uptake and transport of a HIV-1 TAT nonapeptide. Journal of Controlled Release : Official Journal of the Controlled Release Society. 77: 199-212. PMID 11733088 DOI: 10.1016/S0168-3659(01)00474-6  1
2001 Ramanathan S, Pooyan S, Stein S, Prasad PD, Wang J, Leibowitz MJ, Ganapathy V, Sinko PJ. Targeting the sodium-dependent multivitamin transporter (SMVT) for improving the oral absorption properties of a retro-inverso Tat nonapeptide. Pharmaceutical Research. 18: 950-6. PMID 11496954 DOI: 10.1023/A:1010932126662  1
2001 Hoffmann MJ, Sinko PJ, Lee YH, Meeker RJ, Snyder R. Pharmacokinetic studies in Tg.AC and FVB mice administered [14C]benzene either by oral gavage or intradermal injection Toxicology and Applied Pharmacology. 174: 139-145. PMID 11446829 DOI: 10.1006/taap.2001.9203  1
2001 Grass GM, Sinko PJ. Effect of diverse datasets on the predictive capability of ADME models in drug discovery Drug Discovery Today. 6.  1
2000 Balimane PV, Sinko PJ. Effect of ionization on the variable uptake of valacyclovir via the human intestinal peptide transporter (hPepT1) in CHO cells Biopharmaceutics and Drug Disposition. 21: 165-174. PMID 11180195 DOI: 10.1002/1099-081X(200007)21:5<165::AID-BDD225>3.0.CO;2-F  1
2000 Kunta J, Yan J, Makhey VD, Sinko PJ. Active efflux kinetics of etoposide from rabbit small intestine and colon Biopharmaceutics and Drug Disposition. 21: 83-93. PMID 11113881 DOI: 10.1002/1099-081X(200004)21:3<83::AID-BDD220>3.0.CO;2-J  1
2000 Puri N, Sinko PJ. Adjuvancy enhancement of muramyl dipeptide by modulating its release from a physicochemically modified matrix of ovalbumin microspheres. II. In vivo investigation Journal of Controlled Release. 69: 69-80. PMID 11018547 DOI: 10.1016/S0168-3659(00)00290-X  1
2000 Puri N, Kou JH, Sinko PJ. Adjuvancy enhancement of muramyl dipeptide by modulating its release from a physicochemically modified matrix of ovalbumin microspheres. I. In vitro characterization Journal of Controlled Release. 69: 53-67. PMID 11018546 DOI: 10.1016/S0168-3659(00)00289-3  1
2000 Lee YH, Sinko PJ. Oral delivery of salmon calcitonin Advanced Drug Delivery Reviews. 42: 225-238. PMID 10963837 DOI: 10.1016/S0169-409X(00)00063-6  1
2000 Hee Lee Y, Leesman GD, Makhey V, Yu H, Hu P, Perry B, Sutyak JP, Wagner EJ, Falzone LM, Stern W, Sinko PJ. Regional oral absorption, hepatic first-pass effect, and non-linear disposition of salmon calcitonin in beagle dogs. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 50: 205-11. PMID 10962228 DOI: 10.1016/S0939-6411(00)00102-8  1
2000 Sutyak JP, Lee YH, Perry BA, Stern W, Makhey V, Sinko PJ. Improved longevity and functionality of a canine model providing portal vein and multi-site intestinal access Comparative Medicine. 50: 167-174. PMID 10857008  1
2000 Lee YH, Perry BA, Sutyak JP, Stern W, Sinko PJ. Regional differences in intestinal spreading and pH recovery and the impact on salmon calcitonin absorption in dogs Pharmaceutical Research. 17: 284-290. PMID 10801216 DOI: 10.1023/A:1007596821702  1
2000 Puri N, Weyand EH, Abdel-Rahman SM, Sinko PJ. An investigation of the intradermal route as an effective means of immunization for microparticulate vaccine delivery systems Vaccine. 18: 2600-2612. PMID 10775794  1
2000 Norris DA, Leesman GD, Sinko PJ, Grass GM. Development of predictive pharmacokinetic simulation models for drug discovery Journal of Controlled Release. 65: 55-62. PMID 10699270 DOI: 10.1016/S0168-3659(99)00232-1  1
1999 Lee YH, Perry BA, Labruno S, Lee HS, Stern W, Falzone LM, Sinko PJ. Impact of regional intestinal pH modulation on absorption of peptide drugs: Oral absorption studies of salmon calcitonin in beagle dogs Pharmaceutical Research. 16: 1233-1239. PMID 10468025 DOI: 10.1023/A:1014849630520  1
1999 Norris DA, Puri N, Labib ME, Sinko PJ. Determining the absolute surface hydrophobicity of microparticulates using thin layer wicking Journal of Controlled Release. 59: 173-185. PMID 10332052 DOI: 10.1016/S0168-3659(98)00191-6  1
1999 Sinko PJ, Lee YH, Makhey V, Leesman GD, Sutyak JP, Yu H, Perry B, Smith CL, Hu P, Wagner EJ, Falzone LM, McWhorter LT, Gilligan JP, Stern W. Biopharmaceutical approaches for developing and assessing oral peptide delivery strategies and systems: in vitro permeability and in vivo oral absorption of salmon calcitonin (sCT). Pharmaceutical Research. 16: 527-33. PMID 10227707  1
1999 Guo A, Hu P, Balimane PV, Leibach FH, Sinko PJ. Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line Journal of Pharmacology and Experimental Therapeutics. 289: 448-454. PMID 10087037  1
1999 Williams GC, Sinko PJ. Oral absorption of the HIV protease inhibitors: A current update Advanced Drug Delivery Reviews. 39: 211-238. DOI: 10.1016/S0169-409X(99)00027-7  1
1999 Balimane PV, Sinko PJ. Involvement of multiple transporters in the oral absorption of nucleoside analogues Advanced Drug Delivery Reviews. 39: 183-209. DOI: 10.1016/S0169-409X(99)00026-5  1
1999 Sinko PJ. Drug selection in early drug development: Screening for acceptable pharmacokinetic properties using combined in vitro and computational approaches Current Opinion in Drug Discovery and Development. 2: 42-48.  1
1999 Balimane PV, Sinko PJ. Effect of ionization on the variable uptake of valacyclovir via hPepT1, the human intestinal peptide transporter, in CHO cells Proceedings of the Controlled Release Society. 895-896.  1
1999 Puri N, Sinko PJ. Physicochemically modified ovalbumin microspheres mediated adjuvancy enhancement of muramyl dipeptide Proceedings of the Controlled Release Society. 1032-1033.  1
1999 Ramanathan S, Pooyan S, Stein S, Sinko PJ. Investigation of the transport characteristics of a Tat-inhibitor conjugated to a poly(ethylene glycol) based biopolymeric delivery system across Caco-2 cells Proceedings of the Controlled Release Society. 493-494.  1
1998 Balimane PV, Tamai I, Guo A, Nakanishi T, Kitada H, Leibach FH, Tsuji A, Sinko PJ. Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir Biochemical and Biophysical Research Communications. 250: 246-251. PMID 9753615 DOI: 10.1006/bbrc.1998.9298  1
1998 Makhey VD, Guo A, Norris DA, Hu P, Yan J, Sinko PJ. Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells Pharmaceutical Research. 15: 1160-1167. PMID 9706044 DOI: 10.1023/A:1011971303880  1
1998 Sinko PJ, Balimane PV. Carrier-mediated intestinal absorption of valacyclovir, the L-valyl ester prodrug of acyclovir: 1. Interactions with peptides, organic anions and organic cations in rats Biopharmaceutics and Drug Disposition. 19: 209-217. PMID 9604120 DOI: 10.1002/(SICI)1099-081X(199805)19:4<209::AID-BDD93>3.0.CO;2-O  1
1998 Norris DA, Puri N, Sinko PJ. The effect of physical barriers and properties on the oral absorption of particulates Advanced Drug Delivery Reviews. 34: 135-154. DOI: 10.1016/S0169-409X(98)00037-4  1
1998 Puri N, Sinko PJ. Adjuvancy enhancement of muramyl dipeptide by controlling its release from ovalbumin microspheres Proceedings of the Controlled Release Society. 216-217.  1
1997 Yu H, Sinko PJ. Influence of the microporous substratum and hydrodynamics on resistances to drug transport in cell culture systems: Calculation of intrinsic transport parameters Journal of Pharmaceutical Sciences. 86: 1448-1457. PMID 9423161 DOI: 10.1021/js960524q  1
1997 Sinko PJ, Sutyak JP, Leesman GD, Peidi HU, Makhey VD, Hongshi YU, Smith CL. Oral absorption of anti-aids nucleoside analogues: 3. Regional absorption and in vivo permeability of 2', 3'-dideoxyinosine in an intestinal-vascular access port (IVAP) dog model Biopharmaceutics and Drug Disposition. 18: 697-710. PMID 9373726 DOI: 10.1002/(SICI)1099-081X(199711)18:8<697::AID-BDD57>3.0.CO;2-Z  1
1997 Yu H, Cook TJ, Sinko PJ. Evidence for diminished functional expression of intestinal transporters in Caco-2 cell monolayers at high passages. Pharmaceutical Research. 14: 757-62. PMID 9210193 DOI: 10.1023/A:1012150405949  1
1997 Gupta E, Cook TJ, Rubin EH, Sinko PJ. Characterization and in vitro-in vivo correlation of the intestinal permeability of 20(S) camptothecin (CPT1) Faseb Journal. 11.  1
1997 Norris DA, Sinko PJ. Effect of size, surface charge, and hydrophobicity on the translocation of polystyrene microspheres through gastrointestinal mucin Journal of Applied Polymer Science. 63: 1481-1492.  1
1997 Norris DA, Sinko PJ. The role of surface hydrophobicity in the transport of polystyrene microspheres through Caco-2 cell monolayers and intestinal mucin Proceedings of the Controlled Release Society. 17-18.  1
1996 Waclawski AP, Sinko PJ. Oral absorption of anti-acquired immune deficiency syndrome nucleoside analogues. 2. Carrier-mediated intestinal transport of stavudine in rat and rabbit preparations Journal of Pharmaceutical Sciences. 85: 478-485. PMID 8742938 DOI: 10.1021/js950363a  1
1996 Sinko PJ, Leesman GD, Waclawski AP, Yu H, Kou JH. Analysis of intestinal perfusion data for highly permeable drugs using a numerical aqueous resistance - Nonlinear regression method Pharmaceutical Research. 13: 570-576. PMID 8710748 DOI: 10.1023/A:1016098121784  1
1996 Sinko PJ, Hu P. Determining intestinal metabolism and permeability for several compounds in rats. Implications on regional bioavailability in humans Pharmaceutical Research. 13: 108-113. DOI: 10.1023/A:1016041620024  1
1995 Sinko PJ, Hu P, Waclawski AP, Patel NR. Oral absorption of anti‐aids nucleoside analogues. 1. Intestinal transport of didanosine in rat and rabbit preparations Journal of Pharmaceutical Sciences. 84: 959-965. PMID 7500281 DOI: 10.1002/jps.2600840811  1
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