Thomas R. Ward, Ph.D. - Publications

Affiliations: 
Inorganic Chemistry University of Basel, Basel, Basel-Stadt, Switzerland 
Area:
Streptavidin, Artificial Metalloenzymes, Catalysis, Bio-nanotechnology
Website:
http://www.chemie.unibas.ch/~ward/

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Heinisch T, Schwizer F, Garabedian B, Csibra E, Jeschek M, Vallapurackal J, Pinheiro VB, Marlière P, Panke S, Ward TR. Correction: surface display of streptavidin for directed evolution of an allylic deallylase. Chemical Science. 10: 6735. PMID 31367329 DOI: 10.1039/c9sc90139f  0.68
2018 Heinisch T, Schwizer F, Garabedian B, Csibra E, Jeschek M, Vallapurackal J, Pinheiro VB, Marlière P, Panke S, Ward TR. surface display of streptavidin for directed evolution of an allylic deallylase. Chemical Science. 9: 5383-5388. PMID 30079176 DOI: 10.1039/c8sc00484f  0.68
2018 Hestericová M, Heinisch T, Lenz M, Ward TR. Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase. Dalton Transactions (Cambridge, England : 2003). PMID 30019062 DOI: 10.1039/c8dt02224k  0.68
2018 Okamoto Y, Kojima R, Schwizer F, Bartolami E, Heinisch T, Matile S, Fussenegger M, Ward TR. A cell-penetrating artificial metalloenzyme regulates a gene switch in a designer mammalian cell. Nature Communications. 9: 1943. PMID 29769518 DOI: 10.1038/s41467-018-04440-0  0.68
2018 Mann SI, Heinisch T, Ward TR, Borovik AS. Coordination chemistry within a protein host: regulation of the secondary coordination sphere. Chemical Communications (Cambridge, England). PMID 29645031 DOI: 10.1039/c8cc01931b  0.68
2017 Hestericová M, Heinisch T, Alonso-Cotchico L, Maréchal JD, Vidossich P, Ward TR. Directed Evolution of Artificial Imine Reductase. Angewandte Chemie (International Ed. in English). PMID 29265726 DOI: 10.1002/anie.201711016  0.68
2017 Mann SI, Heinisch T, Ward TR, Borovik AS. Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins. Journal of the American Chemical Society. PMID 29117678 DOI: 10.1021/jacs.7b10452  0.68
2017 Schwizer F, Okamoto Y, Heinisch T, Gu Y, Pellizzoni MM, Lebrun V, Reuter R, Köhler V, Lewis JC, Ward TR. Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. Chemical Reviews. PMID 28714313 DOI: 10.1021/acs.chemrev.7b00014  0.68
2016 Jeschek M, Reuter R, Heinisch T, Trindler C, Klehr J, Panke S, Ward TR. Directed evolution of artificial metalloenzymes for in vivo metathesis. Nature. PMID 27571282 DOI: 10.1038/nature19114  1
2016 Heinisch T, Ward TR. Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology: Challenges and Opportunities. Accounts of Chemical Research. PMID 27529561 DOI: 10.1021/acs.accounts.6b00235  1
2016 Keller SG, Pannwitz A, Schwizer F, Klehr J, Wenger OS, Ward TR. Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3](2+)-labeled streptavidin. Organic & Biomolecular Chemistry. PMID 27411288 DOI: 10.1039/c6ob01273f  1
2016 Mann SI, Heinisch T, Weitz AC, Hendrich MP, Ward TR, Borovik AS. Modular Artificial Cupredoxins. Journal of the American Chemical Society. PMID 27385206 DOI: 10.1021/jacs.6b05428  1
2016 Hestericová M, Correro MR, Lenz M, Corvini PF, Shahgaldian P, Ward TR. Immobilization of an artificial imine reductase within silica nanoparticles improves its performance. Chemical Communications (Cambridge, England). PMID 27380900 DOI: 10.1039/c6cc04604e  1
2016 Okamoto Y, Ward TR, Wenger OS. From Photodriven Charge Accumulation to Fueling Enzyme Cascades in Molecular Factories. Chimia. 70: 395-7. PMID 27363366 DOI: 10.2533/chimia.2016.395  1
2016 Okamoto Y, Köhler V, Ward TR. An NAD(P)H-dependent Artificial Transfer Hydrogenase for Multi-enzymatic Cascades. Journal of the American Chemical Society. PMID 27100673 DOI: 10.1021/jacs.6b02470  1
2016 Hyster TK, Ward TR. Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions. Angewandte Chemie (International Ed. in English). PMID 26971363 DOI: 10.1002/anie.201508816  1
2016 Chatterjee A, Ward TR. Recent Advances in the Palladium Catalyzed Suzuki–Miyaura Cross-Coupling Reaction in Water Catalysis Letters. 1-21. DOI: 10.1007/s10562-016-1707-8  1
2016 Mérel DS, Gaillard S, Ward TR, Renaud JL. Achiral Cyclopentadienone Iron Tricarbonyl Complexes Embedded in Streptavidin: An Access to Artificial Iron Hydrogenases and Application in Asymmetric Hydrogenation Catalysis Letters. 146: 564-569. DOI: 10.1007/s10562-015-1681-6  1
2015 Reuter R, Ward TR. Profluorescent substrates for the screening of olefin metathesis catalysts. Beilstein Journal of Organic Chemistry. 11: 1886-1892. PMID 26664607 DOI: 10.3762/bjoc.11.203  1
2015 Heinisch T, Pellizzoni M, Dürrenberger M, Tinberg CE, Köhler V, Klehr J, Häussinger D, Baker D, Ward TR. Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. Journal of the American Chemical Society. 137: 10414-9. PMID 26226626 DOI: 10.1021/jacs.5b06622  1
2015 Zhao J, Kajetanowicz A, Ward TR. Carbonic anhydrase II as host protein for the creation of a biocompatible artificial metathesase. Organic & Biomolecular Chemistry. 13: 5652-5. PMID 25894419 DOI: 10.1039/c5ob00428d  1
2015 Chatterjee A, Mallin H, Klehr J, Vallapurackal J, Finke AD, Vera L, Marsh M, Ward TR. An enantioselective artificial Suzukiase based on the biotin-streptavidin technology Chemical Science. 7: 673-677. DOI: 10.1039/c5sc03116h  1
2015 Fujieda N, Schätti J, Stuttfeld E, Ohkubo K, Maier T, Fukuzumi S, Ward TR. Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding Chemical Science. 6: 4060-4065. DOI: 10.1039/c5sc01065a  1
2015 Quinto T, Häussinger D, Köhler V, Ward TR. Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD2H Organic and Biomolecular Chemistry. 13: 357-360. DOI: 10.1039/c4ob02071e  1
2015 Mi?opolska EA, Kuss-Petermann M, Neuburger M, Wenger O, Ward TR. N-Heterocyclic carbene ligands bearing a naphthoquinone appendage: Synthesis and coordination chemistry Polyhedron. DOI: 10.1016/j.poly.2015.04.019  1
2015 Ward TR, Köhler V. Editorial overview: Biocatalysis and biotransformation: Bio-inspired, bio-based and bio-linked catalysis Current Opinion in Chemical Biology. DOI: 10.1016/j.cbpa.2015.02.022  1
2015 Heinisch T, Ward TR. Latest Developments in Metalloenzyme Design and Repurposing European Journal of Inorganic Chemistry. DOI: 10.1002/ejic.201500408  1
2014 Robles VM, Dürrenberger M, Heinisch T, Lledós A, Schirmer T, Ward TR, Maréchal JD. Structural, kinetic, and docking studies of artificial imine reductases based on biotin-streptavidin technology: an induced lock-and-key hypothesis. Journal of the American Chemical Society. 136: 15676-83. PMID 25317660 DOI: 10.1021/ja508258t  0.68
2014 Wilson YM, Dürrenberger M, Nogueira ES, Ward TR. Neutralizing the detrimental effect of glutathione on precious metal catalysts Journal of the American Chemical Society. 136: 8928-8932. PMID 24918731 DOI: 10.1021/ja500613n  1
2014 Dürrenberger M, Ward TR. Recent achievments in the design and engineering of artificial metalloenzymes Current Opinion in Chemical Biology. 19: 99-106. PMID 24608081 DOI: 10.1016/j.cbpa.2014.01.018  1
2014 Nogueira ES, Schleier T, Dürrenberger M, Ballmer-Hofer K, Ward TR, Jaussi R. High-level secretion of recombinant full-length streptavidin in Pichia pastoris and its application to enantioselective catalysis. Protein Expression and Purification. 93: 54-62. PMID 24184946 DOI: 10.1016/j.pep.2013.10.015  0.68
2014 Robles VM, Dürrenberger M, Heinisch T, Lledós A, Schirmer T, Ward TR, Maréchal JD. Structural, kinetic, and docking studies of artificial imine reductases based on biotin-streptavidin technology: An induced lock-and-key hypothesis Journal of the American Chemical Society. 136: 15676-15683. DOI: 10.1021/ja508258t  1
2014 Muñoz Robles V, Vidossich P, Lledós A, Ward TR, Maréchal JD. Computational insights on an artificial imine reductase based on the biotin-streptavidin technology Acs Catalysis. 4: 833-842. DOI: 10.1021/cs400921n  1
2014 Nogueira ES, Schleier T, Dürrenberger M, Ballmer-Hofer K, Ward TR, Jaussi R. High-level secretion of recombinant full-length streptavidin in Pichia pastoris and its application to enantioselective catalysis Protein Expression and Purification. 93: 54-62. DOI: 10.1016/j.pep.2013.10.015  1
2014 Quinto T, Köhler V, Ward TR. Recent trends in biomimetic NADH regeneration Topics in Catalysis. 57: 321-331. DOI: 10.1007/s11244-013-0187-y  1
2014 Turner NJ, Whittall J, Ward TR. Foreword Topics in Catalysis. 57: 283. DOI: 10.1007/s11244-013-0186-z  1
2014 Kajetanowicz A, Chatterjee A, Reuter R, Ward TR. Biotinylated metathesis catalysts: Synthesis and performance in ring closing metathesis Catalysis Letters. 144: 373-379. DOI: 10.1007/s10562-013-1179-z  1
2014 Keller SG, Ringenberg MR, Häussinger D, Ward TR. Evaluation of the formate dehydrogenase activity of three-legged pianostool complexes in dilute aqueous solution European Journal of Inorganic Chemistry. 2014: 5860-5864. DOI: 10.1002/ejic.201402348  1
2014 Köhler V, Ward TR. Concurrent cross metathesis and enzymatic oxidation: Enabling off-equilibrium transformations Chemcatchem. 6: 2191-2193. DOI: 10.1002/cctc.201402150  1
2014 Genz M, Köhler V, Krauss M, Singer D, Hoffmann R, Ward TR, Sträter N. An artificial imine reductase based on the ribonuclease S scaffold Chemcatchem. 6: 736-740. DOI: 10.1002/cctc.201300995  1
2014 Quinto T, Schwizer F, Zimbron JM, Morina A, Köhler V, Ward TR. Expanding the chemical diversity in artificial imine reductases based on the biotin-streptavidin technology Chemcatchem. 6: 1010-1014. DOI: 10.1002/cctc.201300825  1
2013 Schmid MH, Ward TR, Meuwly M. Toward a Broadly Applicable Force Field for d(6)-Piano Stool Complexes. Journal of Chemical Theory and Computation. 9: 2313-23. PMID 26583724 DOI: 10.1021/ct301080d  0.52
2013 Bereau T, Kramer C, Monnard FW, Nogueira ES, Ward TR, Meuwly M. Scoring multipole electrostatics in condensed-phase atomistic simulations. The Journal of Physical Chemistry. B. 117: 5460-71. PMID 23560873 DOI: 10.1021/jp400593c  0.68
2013 Zimbron JM, Heinisch T, Schmid M, Hamels D, Nogueira ES, Schirmer T, Ward TR. A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin-streptavidin technology Journal of the American Chemical Society. 135: 5384-5388. PMID 23496309 DOI: 10.1021/ja309974s  1
2013 Köhler V, Wilson YM, Dürrenberger M, Ghislieri D, Churakova E, Quinto T, Knörr L, Häussinger D, Hollmann F, Turner NJ, Ward TR. Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes. Nature Chemistry. 5: 93-9. PMID 23344429 DOI: 10.1038/nchem.1498  1
2013 Monnard FW, Nogueira ES, Heinisch T, Schirmer T, Ward TR. Human carbonic anhydrase II as host protein for the creation of artificial metalloenzymes: The asymmetric transfer hydrogenation of imines Chemical Science. 4: 3269-3274. DOI: 10.1039/c3sc51065d  1
2013 Bereau T, Kramer C, Monnard FW, Nogueira ES, Ward TR, Meuwly M. Scoring multipole electrostatics in condensed-phase atomistic simulations Journal of Physical Chemistry B. 117: 5460-5471. DOI: 10.1021/jp400593c  1
2013 Schmid MH, Ward TR, Meuwly M. Toward a broadly applicable force field for d6-piano stool complexes Journal of Chemical Theory and Computation. 9: 2313-2323. DOI: 10.1021/ct301080d  1
2013 Schwizer F, Köhler V, Dürrenberger M, Knörr L, Ward TR. Genetic optimization of the catalytic efficiency of artificial imine reductases based on biotin-streptavidin technology Acs Catalysis. 3: 1752-1755. DOI: 10.1021/cs400428r  1
2013 Hamels DR, Ward TR. Biomacromolecules as Ligands for Artificial Metalloenzymes Comprehensive Inorganic Chemistry Ii (Second Edition): From Elements to Applications. 6: 737-761. DOI: 10.1016/B978-0-08-097774-4.00626-4  1
2013 Heinisch T, Langowska K, Tanner P, Reymond JL, Meier W, Palivan C, Ward TR. Fluorescence-Based Assay for the Optimization of the Activity of Artificial Transfer Hydrogenase within a Biocompatible Compartment Chemcatchem. 5: 720-723. DOI: 10.1002/cctc.201200834  1
2013 Praneeth VKK, Ward TR. Metal-Catalyzed Organic Transformations Inside a Protein Scaffold using Artificial Metalloenzymes Coordination Chemistry in Protein Cages: Principles, Design, and Applications. 203-219. DOI: 10.1002/9781118571811.ch8  1
2012 Hyster TK, Knörr L, Ward TR, Rovis T. Biotinylated Rh(III) complexes in engineered streptavidin for accelerated asymmetric C-H activation. Science (New York, N.Y.). 338: 500-3. PMID 23112327 DOI: 10.1126/science.1226132  1
2012 Amrein B, Schmid M, Collet G, Cuniasse P, Gilardoni F, Seebeck FP, Ward TR. Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals Metallomics. 4: 379-388. PMID 22392271 DOI: 10.1039/c2mt20010d  1
2012 Oohora K, Burazerovic S, Onoda A, Wilson YM, Ward TR, Hayashi T. Chemically programmed supramolecular assembly of hemoprotein and streptavidin with alternating alignment. Angewandte Chemie (International Ed. in English). 51: 3818-21. PMID 22334508 DOI: 10.1002/anie.201107067  1
2012 Schmid M, Nogueira ES, Monnard FW, Ward TR, Meuwly M. Arylsulfonamides as inhibitors for carbonic anhydrase: Prediction & validation Chemical Science. 3: 690-700. DOI: 10.1039/c1sc00628b  1
2012 Ward TR, Pordea A. 7.24 Enantioselective Hybrid Catalysts Comprehensive Chirality. 7: 516-552. DOI: 10.1016/B978-0-08-095167-6.00734-5  1
2012 Praneeth VKK, Ringenberg MR, Ward TR. Redox-active ligands in catalysis Angewandte Chemie - International Edition. 51: 10228-10234. DOI: 10.1002/anie.201204100  1
2011 Mayer C, Gillingham DG, Ward TR, Hilvert D. An artificial metalloenzyme for olefin metathesis Chemical Communications. 47: 12068-12070. PMID 21991583 DOI: 10.1039/c1cc15005g  1
2011 Lo C, Ringenberg MR, Gnandt D, Wilson Y, Ward TR. Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology Chemical Communications. 47: 12065-12067. PMID 21959544 DOI: 10.1039/c1cc15004a  1
2011 Köhler V, Mao J, Heinisch T, Pordea A, Sardo A, Wilson YM, Knörr L, Creus M, Prost JC, Schirmer T, Ward TR. OsO4·streptavidin: a tunable hybrid catalyst for the enantioselective cis-dihydroxylation of olefins. Angewandte Chemie (International Ed. in English). 50: 10863-6. PMID 21948623 DOI: 10.1002/anie.201103632  1
2011 Monnard FW, Heinisch T, Nogueira ES, Schirmer T, Ward TR. Human Carbonic Anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor Chemical Communications. 47: 8238-8240. PMID 21706094 DOI: 10.1039/c1cc10345h  1
2011 Ringenberg MR, Ward TR. Merging the best of two worlds: Artificial metalloenzymes for enantioselective catalysis Chemical Communications. 47: 8470-8476. PMID 21603692 DOI: 10.1039/c1cc11592h  1
2011 Dürrenberger M, Heinisch T, Wilson YM, Rossel T, Nogueira E, Knörr L, Mutschler A, Kersten K, Zimbron MJ, Pierron J, Schirmer T, Ward TR. Artificial transfer hydrogenases for the enantioselective reduction of cyclic imines. Angewandte Chemie (International Ed. in English). 50: 3026-9. PMID 21404391 DOI: 10.1002/anie.201007820  1
2011 Sardo A, Wohlschlager T, Lo C, Zoller H, Ward TR, Creus M. Burkavidin: A novel secreted biotin-binding protein from the human pathogen Burkholderia pseudomallei Protein Expression and Purification. 77: 131-139. PMID 21241807 DOI: 10.1016/j.pep.2011.01.003  1
2011 Ward TR. Artificial metalloenzymes based on the biotin - Avidin technology: Enantioselective catalysis and beyond Accounts of Chemical Research. 44: 47-57. PMID 20949947 DOI: 10.1021/ar100099u  1
2011 Creus M, Ward TR. Design and evolution of artificial metalloenzymes: Biomimetic aspects Progress in Inorganic Chemistry. 57: 203-253.  1
2010 Constable EC, Housecroft CE, Creus M, Gademann K, Giese B, Ward TR, Woggon WD, Chougnet A. Bioorganic and bioinorganic chemistry. Chimia. 64: 846-54. PMID 21268991 DOI: 10.2533/chimia.2010.846  1
2010 Köhler V, Wilson YM, Lo C, Sardo A, Ward TR. Protein-based hybrid catalysts-design and evolution Current Opinion in Biotechnology. 21: 744-752. PMID 20926284 DOI: 10.1016/j.copbio.2010.09.004  1
2010 Zimbron JM, Sardo A, Heinisch T, Wohlschlager T, Gradinaru J, Massa C, Schirmer T, Creus M, Ward TR. Chemo-genetic optimization of DNA recognition by metallodrugs using a presenter-protein strategy Chemistry - a European Journal. 16: 12883-12889. PMID 20878805 DOI: 10.1002/chem.201001573  1
2010 Panek JJ, Ward TR, Jezierska-Mazzarello A, Novi? M. Flexibility of a biotinylated ligand in artificial metalloenzymes based on streptavidin-an insight from molecular dynamics simulations with classical and ab initio force fields Journal of Computer-Aided Molecular Design. 24: 719-732. PMID 20526651 DOI: 10.1007/s10822-010-9369-x  1
2010 Heinisch T, Ward TR. Design strategies for the creation of artificial metalloenzymes Current Opinion in Chemical Biology. 14: 184-199. PMID 20071213 DOI: 10.1016/j.cbpa.2009.11.026  1
2010 Pordea A, Creus M, Letondor C, Ivanova A, Ward TR. Improving the enantioselectivity of artificial transfer hydrogenases based on the biotin-streptavidin technology by combinations of point mutations Inorganica Chimica Acta. 363: 601-604. DOI: 10.1016/j.ica.2009.02.001  1
2010 Köhler V, Ward TR. Design of a functional nitric oxide reductase within a myoglobin scaffold Chembiochem. 11: 1009. DOI: 10.1002/cbic.201000093  1
2010 Mao J, Ward TR. Proteins as Host for Enantioselective Catalysis: Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology Molecular Encapsulation: Organic Reactions in Constrained Systems. 361-376. DOI: 10.1002/9780470664872.ch13  1
2010 Burazerovic S, Ward TR. Hierarchical self-assembly of one and two dimensional Protein networks European Cells and Materials. 20: 32.  1
2009 Fürstenberg A, Kel O, Gradinaru J, Ward TR, Emery D, Bollot G, Mareda J, Vauthey E. Site-dependent excited-state dynamics of a fluorescent probe bound to avidin and streptavidin Chemphyschem. 10: 1517-1532. PMID 19565577 DOI: 10.1002/cphc.200900132  1
2009 Panek JJ, Ward TR, Jezierska A, Novi? M. Effects of tryptophan residue fluorination on streptavidin stability and biotin-streptavidin interactions via molecular dynamics simulations Journal of Molecular Modeling. 15: 257-266. PMID 19052784 DOI: 10.1007/s00894-008-0382-0  1
2009 Pordea A, Ward TR. Artificial metalloenzymes: Combining the best features of homogeneous and enzymatic catalysis Synlett. 3225-3236. DOI: 10.1055/s-0029-1218305  1
2009 Pordea A, Mathis D, Ward TR. Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation Journal of Organometallic Chemistry. 694: 930-936. DOI: 10.1016/j.jorganchem.2008.11.023  1
2009 Steinreiber J, Ward TR. Artificial metalloenzymes for enantioselective catalysis based on the biotin-avidin technology Topics in Organometallic Chemistry. 25: 93-112. DOI: 10.1007/978-3-540-87757-8_5  1
2008 Pordea A, Ward TR. Chemogenetic protein engineering: An efficient tool for the optimization of artificial metalloenzymes Chemical Communications. 4239-4249. PMID 18802535 DOI: 10.1039/b806652c  1
2008 Ward TR. Artificial enzymes made to order: Combination of computational design and directed evolution Angewandte Chemie - International Edition. 47: 7802-7803. PMID 18780363 DOI: 10.1002/anie.200802865  1
2008 Pordea A, Creus M, Panek J, Duboc C, Mathis D, Novic M, Ward TR. Artificial metalloenzyme for enantioselective sulfoxidation based on vanadyl-loaded streptavidin. Journal of the American Chemical Society. 130: 8085-8. PMID 18507383 DOI: 10.1021/ja8017219  1
2008 Han A, Creus M, Schürmann G, Linder V, Ward TR, De Rooij NF, Staufer U. Label-free detection of single protein molecules and protein-protein interactions using synthetic nanopores Analytical Chemistry. 80: 4651-4658. PMID 18470996 DOI: 10.1021/ac7025207  1
2008 Pierron J, Malan C, Creus M, Gradinaru J, Hafner I, Ivanova A, Sardo A, Ward TR. Artificial metalloenzymes for asymmetric allylic alkylation on the basis of the biotin-avidin technology Angewandte Chemie - International Edition. 47: 701-705. PMID 18181264 DOI: 10.1002/anie.200703159  1
2008 Creus M, Pordea A, Rossel T, Sardo A, Letondor C, Ivanova A, LeTrong I, Stenkamp RE, Ward TR. X-ray structure and designed evolution of an artificial transfer hydrogenase Angewandte Chemie - International Edition. 47: 1400-1404. PMID 18176932 DOI: 10.1002/anie.200704865  1
2008 Steinreiber J, Ward TR. Artificial metalloenzymes as selective catalysts in aqueous media Coordination Chemistry Reviews. 252: 751-766. DOI: 10.1016/j.ccr.2007.09.016  1
2007 Mazurek S, Ward TR, Novi? M. Counter propagation artificial neural networks modeling of an enantioselectivity of artificial metalloenzymes Molecular Diversity. 11: 141-152. PMID 18317943 DOI: 10.1007/s11030-008-9068-x  1
2007 Humbert N, Schürmann P, Zocchi A, Neuhaus JM, Ward TR. High-yield production and purification of recombinant T7-tag mature streptavidin in glucose-stressed E. coli Methods in Molecular Biology. 418: 101-110. PMID 18287653  1
2007 Humbert N, Ward TR. Functionality screen of streptavidin mutants by non-denaturing SDS-PAGE using biotin-4-fluorescein Methods in Molecular Biology. 418: 63-71. PMID 18287650  1
2007 Creus M, Ward TR. Designed evolution of artificial metalloenzymes: Protein catalysts made to order Organic and Biomolecular Chemistry. 5: 1835-1844. PMID 17551630 DOI: 10.1039/b702068f  1
2007 Burazerovic S, Gradinaru J, Pierron J, Ward TR. Hierarchical self-assembly of one-dimensional streptavidin bundles as a collagen mimetic for the biomineralization of calcite Angewandte Chemie - International Edition. 46: 5510-5514. PMID 17523206 DOI: 10.1002/anie.200701080  1
2007 Rusbandi UE, Skander M, Ivanova A, Malan C, Ward TR. Second-generation artificial hydrogenases based on the biotin-avidin technology: Improving selectivity and organic solvent tolerance by introduction of an (R)-proline spacer Comptes Rendus Chimie. 10: 678-683. DOI: 10.1016/j.crci.2007.02.020  1
2007 Rusbandi UE, Lo C, Skander M, Ivanova A, Creus M, Humbert N, Ward TR. Second generation artificial hydrogenases based on the biotin-avidin technology: Improving activity, stability and selectivity by introduction of enantiopure amino acid spacers Advanced Synthesis and Catalysis. 349: 1923-1930. DOI: 10.1002/adsc.200700022  1
2006 Letondor C, Ward TR. Artificial metalloenzymes for enantioselective catalysis: Recent advances Chembiochem. 7: 1845-1852. PMID 17004276 DOI: 10.1002/cbic.200600264  1
2006 Letondor C, Pordea A, Humbert N, Ivanova A, Mazurek S, Novic M, Ward TR. Artificial transfer hydrogenases based on the biotin-(strept)avidin technology: Fine tuning the selectivity by saturation mutagenesis of the host protein Journal of the American Chemical Society. 128: 8320-8328. PMID 16787096 DOI: 10.1021/ja061580o  1
2006 Loosli A, Rusbandi UE, Gradinaru J, Bernauer K, Schlaepfer CW, Meyer M, Mazurek S, Novic M, Ward TR. (Strept)avidin as host for biotinylated coordination complexes: stability, chiral discrimination, and cooperativity Inorganic Chemistry. 45: 660-668. PMID 16411701 DOI: 10.1021/ic051405t  1
2006 Le Trong I, Humbert N, Ward TR, Stenkamp RE. Crystallographic analysis of a full-length streptavidin with its C-terminal polypeptide bound in the biotin binding site Journal of Molecular Biology. 356: 738-745. PMID 16384581 DOI: 10.1016/j.jmb.2005.11.086  1
2006 Delahaye S, Loosli C, Liu SX, Decurtins S, Labat G, Neels A, Loosli A, Ward TR, Hauser A. Inter- And intramolecular interactions in some supramolecular photochemical systems Advanced Functional Materials. 16: 286-295. DOI: 10.1002/adfm.200500329  1
2005 Klein G, Humbert N, Gradinaru J, Ivanova A, Gilardoni F, Rusbandi UE, Ward TR. Tailoring the active site of chemzymes by using a chemogenetic-optimization procedure: Towards substrate-specific artificial hydrogenases based on the biotin-avidin technology Angewandte Chemie - International Edition. 44: 7764-7767. PMID 16276543 DOI: 10.1002/anie.200502000  1
2005 Skander M, Malan C, Ivanova A, Ward TR. Chemical optimization of artificial metalloenzymes based on the biotin-avidin technology: (S)-selective and solvent-tolerant hydrogenation catalysts via the introduction of chiral amino acid spacers Chemical Communications. 4815-4817. PMID 16193124 DOI: 10.1039/b509015f  1
2005 Thomas CM, Ward TR. Artificial metalloenzymes: proteins as hosts for enantioselective catalysis. Chemical Society Reviews. 34: 337-46. PMID 15778767 DOI: 10.1039/b314695m  1
2005 Letondor C, Humbert N, Ward TR. Artificial metalloenzymes based on biotin-avidin technology for the enantioselective reduction of ketones by transfer hydrogenation. Proceedings of the National Academy of Sciences of the United States of America. 102: 4683-7. PMID 15772162 DOI: 10.1073/pnas.0409684102  1
2005 Ward TR. Artificial metalloenzymes for enantioselective catalysis based on the noncovalent incorporation of organometallic moieties in a host protein Chemistry - a European Journal. 11: 3798-3804. PMID 15761912 DOI: 10.1002/chem.200401232  1
2005 Humbert N, Zocchi A, Ward TR. Electrophoretic behavior of streptavidin complexed to a biotinylated probe: a functional screening assay for biotin-binding proteins. Electrophoresis. 26: 47-52. PMID 15624156 DOI: 10.1002/elps.200406148  1
2005 Vieille-Petit L, Süss-Fink G, Therrien B, Ward TR, Stœckli-Evans H, Labat G, Karmazin-Brelot L, Neels A, Bürgi T, Finke RG, Hagen CM. Synthesis and characterization of tetrahedral Ru3O clusters with intrinsic framework chirality: A chiral probe of the intact cluster catalysis concept Organometallics. 24: 6104-6119. DOI: 10.1021/om050643t  1
2005 Thomas CM, Letondor C, Humbert N, Ward TR. Aqueous oxidation of alcohols catalyzed by artificial metalloenzymes based on the biotin-avidin technology Journal of Organometallic Chemistry. 690: 4488-4491. DOI: 10.1016/j.jorganchem.2005.02.001  1
2005 Thomas CM, Ward TR. Design of artificial metalloenzymes Applied Organometallic Chemistry. 19: 35-39. DOI: 10.1002/aoc.726  1
2004 Skander M, Humbert N, Collot J, Gradinaru J, Klein G, Loosli A, Sauser J, Zocchi A, Gilardoni F, Ward TR. Artificial metalloenzymes: (strept)avidin as host for enantioselective hydrogenation by achiral biotinylated rhodium-diphosphine complexes. Journal of the American Chemical Society. 126: 14411-8. PMID 15521760 DOI: 10.1021/ja0476718  1
2004 Collot J, Humbert N, Skander M, Klein G, Ward TR. Artificial metalloenzymes for enantioselective catalysis: The phenomenon of protein accelerated catalysis Journal of Organometallic Chemistry. 689: 4868-4871. DOI: 10.1016/j.jorganchem.2004.09.032  1
2004 Süss-Fink G, Therrien B, Vieille-Petit L, Tschan M, Romakh VB, Ward TR, Dadras M, Laurenczy G. Supramolecular cluster catalysis: Facts and problems Journal of Organometallic Chemistry. 689: 1362-1369. DOI: 10.1016/j.jorganchem.2003.12.032  1
2004 Klotz A, Ward T, Dartois E. Molecular complexes theoretical computations between methanol and carbon dioxide and their implications in the interstellar ice mantles Astronomy and Astrophysics. 416: 801-810.  1
2003 Collot J, Gradinaru J, Humbert N, Skander M, Zocchi A, Ward TR. Artificial metalloenzymes for enantioselective catalysis based on biotin-avidin. Journal of the American Chemical Society. 125: 9030-1. PMID 15369356 DOI: 10.1021/ja035545i  1
2003 Zocchi A, Jobé AM, Neuhaus JM, Ward TR. Expression and purification of a recombinant avidin with a lowered isoelectric point in Pichia pastoris. Protein Expression and Purification. 32: 167-74. PMID 14965761 DOI: 10.1016/j.pep.2003.09.001  1
2003 Vieille-Petit L, Therrien B, Süss-Fink G, Ward TR. Isolation and single-crystal X-ray structure analysis of the catalyst-substrate host-guest complexes [C6H6⊂H 3Ru3{C6H5(CH2) nOH}(C6Me6)2(O)]+ (n=2, 3) Journal of Organometallic Chemistry. 684: 117-123. DOI: 10.1016/S0022-328X(03)00519-9  1
2003 Zocchi A, Humbert N, Berta T, Ward TR. Efficient Expression and Mutation of Avidin and Streptavidin as Host Proteins for Enantioselective Catalysis Chimia. 57: 589-592.  1
2003 Ward TR, Collot J, Gradinaru J, Loosli A, Skander M, Letondor C, Joseph E, Klein G. Exploiting the Second Coordination Sphere: Proteins as Host for Enantioselective Catalysis Chimia. 57: 586-588.  1
2002 Süss-Fink G, Faure M, Ward TR. Supramolecular cluster catalysis: benzene hydrogenation catalyzed by a cationic triruthenium cluster under biphasic conditions. Angewandte Chemie (International Ed. in English). 41: 99-101. PMID 12491450 DOI: 10.1002/1521-3773(20020104)41:1<99::AID-ANIE99>3.0.CO;2-E  1
2002 Laurenczy G, Faure M, Vieille-Petit L, Süss-Fink G, Ward TR. Mechanistic in situ High-Pressure NMR Studies of Benzene Hydrogenation by Supramolecular Cluster Catalysis with [(η6-C6H6)(η6-C 6Me6)2Ru3(μ 3-O)(μ2-OH)(μ2-H)2][BF 4] Advanced Synthesis and Catalysis. 344: 1073-1077. DOI: 10.1002/1615-4169(200212)344:10<1073::AID-ADSC1073>3.0.CO;2-J  1
2001 Duclos S, Stoeckli-Evans H, Ward TR. Design and synthesis of compartmental ligands and their complexes for the production of catalytic antibodies Helvetica Chimica Acta. 84: 3148-3161. DOI: 10.1002/1522-2675(20011017)84:10<3148::AID-HLCA3148>3.0.CO;2-W  1
2000 Brändli C, Ward TR. A Versatile Approach to the Solution-Phase Combinatorial Synthesis of Substituted Pyridines: The Cobalt-Catalyzed Cyclotrimerization of Alkynes with a Nitrile. Journal of Combinatorial Chemistry. 2: 42-47. PMID 10813884  1
1999 Ward TR, Lutz A, Parel SP, Ensling J, Gütlich P, Buglyó P, Orvig C. An Iron-Based Molecular Redox Switch as a Model for Iron Release from Enterobactin via the Salicylate Binding Mode. Inorganic Chemistry. 38: 5007-5017. PMID 11671244  1
1999 Therrien B, König A, Ward TR. Synthesis of a configurationally stable three-legged piano-stool complex Organometallics. 18: 1565-1568. DOI: 10.1002/(SICI)1521-3773(19990201)38:3<405::AID-ANIE405>3.0.CO;2-0  1
1999 Ward TR. From catalyst design to molecular devices: Theory and experiments Chimia. 53: 19-28.  1
1998 Brändli C, Ward TR. Libraries via Metathesis of Internal Olefins Helvetica Chimica Acta. 81: 1616-1621.  1
1998 Ward TR, Duclos S, Therrien B, Schenk K. Coordination properties of Kläui's tripodal oxygen donor toward zirconium(IV) Organometallics. 17: 2490-2494.  1
1998 Gilardoni F, Weber J, Chermette H, Ward TR. Reactivity indices in density functional theory: A new evaluation of the condensed Fukui function by numerical integration Journal of Physical Chemistry A. 102: 3607-3613.  1
1998 Lutz A, Ward TR. Tripodal Dodecadentate Ligands with Salicylamide and Bipyridine Binding Sites for Iron(II) and Iron(III) Coordination Helvetica Chimica Acta. 81: 207-218.  1
1998 Therrien B, Ward TR, Pilkington M, Hoffmann C, Gilardoni F, Weber J. Synthesis and reactivity of tethered η1:η6-(phosphinoarene)ruthenium bichlorides Organometallics. 17: 330-337.  1
1997 Ward TR, Bürgi HB, Gilardoni F, Weber J. Edge-bridged tetrahedral geometry of five-coordinate d0 complexes, relatives of the bent [MCp2L3] familie: A theoretical and structure-correlation study Journal of the American Chemical Society. 119: 11974-11985. DOI: 10.1021/ja972230s  1
1997 Ward TR. Electronic asymmetry: Theoretical background, ligand design, and applications Chimia. 51: 238-240.  1
1997 Ward TR, Schafer O, Daul C, Hofmann P. Geometry of coordinatively unsaturated two-legged piano stool complexes with 16 valence electrons: A theoretical study Organometallics. 16: 3207-3215.  1
1996 Lutz A, Ward TR, Albrecht M. Synthesis of salicylamide and bipyridine containing ligands for iron(II) and iron(III) coordination Tetrahedron. 52: 12197-12208. DOI: 10.1016/0040-4020(96)00724-7  1
1996 Ward TR. Regioselectivity of nucleophilic attack on [Pd(allyl)(phosphine)(imine)] complexes: A theoretical study Organometallics. 15: 2836-2838.  1
1996 Marfurt J, Stulz E, Trafelet HU, Zingg A, Leumann C, Hazenkamp M, Judd R, Schenker S, Strouse G, Ward TR, Förtsch M, Hauser J, Bürgi HB. 7-(2′-Deoxy-α-D-ribofuranosyl)-hypoxanthine Acta Crystallographica Section C: Crystal Structure Communications. 52: 713-716.  1
1995 Giannini L, Solari E, De Angelis S, Ward TR, Floriani C, Chiesi-Villa A, Rizzoli C. Migratory aptitude of the Zr-C functionalities bonded to a macrocyclic structure: Thermally- and solvent-assisted intra- and intermolecular migrations in dialkyl(dibenzotetramethyltetraazaannulene)zirconium(IV) Journal of the American Chemical Society. 117: 5801-5811.  1
1993 Ward TR, Hoffmann R, Shelef M. Coupling nitrosyls as the first step in the reduction of NO on metal surfaces: the special role of rhodium Surface Science. 289: 85-99. DOI: 10.1016/0039-6028(93)90890-V  1
1993 Ward TR, Alemany P, Hoffmann R. Adhesion of rhodium, palladium, and platinum to alumina and the reduction of NO on the resulting surfaces: A theoretical analysis Journal of Physical Chemistry. 97: 7691-7699.  1
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