| Year |
Citation |
Score |
| 2019 |
Zhang H, Zhu D, Zhang Z, Kaluz S, Yu B, Devi NS, Olson JJ, Van Meir EG. EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway. Oncogene. PMID 31582835 DOI: 10.1038/s41388-019-1036-7 |
0.306 |
|
| 2018 |
Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, ... ... Van Meir EG, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. Cancer Cell. 33: 1004-1016.e5. PMID 29894688 DOI: 10.1016/J.Ccell.2018.05.006 |
0.315 |
|
| 2016 |
Bolyard CM, Meisen WH, Banasavadi-Siddegowda Y, Hardcastle J, Yoo JY, Wohleb ES, Wojton J, Yu JG, Dubin S, Khosla M, Xu B, Smith JG, Alvarez-Breckenridge C, Pow-Anpongkul P, Pichiorri F, ... ... Van Meir EG, et al. BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection- implications for Oncolytic Viral Therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27852701 DOI: 10.1158/1078-0432.Ccr-16-1818 |
0.627 |
|
| 2016 |
Aust G, Zhu D, Van Meir EG, Xu L. Adhesion GPCRs in Tumorigenesis. Handbook of Experimental Pharmacology. 234: 369-396. PMID 27832497 DOI: 10.1007/978-3-319-41523-9_17 |
0.324 |
|
| 2014 |
Wojton J, Meisen WH, Jacob NK, Thorne AH, Hardcastle J, Denton N, Chu Z, Dmitrieva N, Marsh R, Van Meir EG, Kwon CH, Chakravarti A, Qi X, Kaur B. SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma. Oncotarget. 5: 9703-9. PMID 25210852 DOI: 10.18632/Oncotarget.2232 |
0.698 |
|
| 2014 |
Zerrouqi A, Pyrzynska B, Brat DJ, Van Meir EG. P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway. Cancer Research. 74: 1371-8. PMID 24398474 DOI: 10.1158/0008-5472.Can-13-1951 |
0.317 |
|
| 2014 |
Van Meir EG, Lee S, Khwaja FW, Zerrouqi A, Zhang Z, Olson JJ, Kaluzova M, Hadjipanayis CG, Devi NS. A NOVEL P53 BYSTANDER EFFECT INDUCES GLIOBLASTOMA CELL DEATH THROUGH A GLYCOSYLATION-DEPENDENT MECHANISM Neuro-Oncology. 16: iii19-iii19. DOI: 10.1093/Neuonc/Nou206.70 |
0.767 |
|
| 2013 |
Stephenson JR, Paavola KJ, Schaefer SA, Kaur B, Van Meir EG, Hall RA. Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density. The Journal of Biological Chemistry. 288: 22248-56. PMID 23782696 DOI: 10.1074/Jbc.M113.489757 |
0.454 |
|
| 2012 |
Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, Zhang Z, Boreddy PR, Wang W, Wang Z, Abbruscato T, Chen Z, Olson JJ, Zhang R, Goodman MM, ... ... Van Meir EG, et al. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6623-33. PMID 22923450 DOI: 10.1158/1078-0432.Ccr-12-0861 |
0.344 |
|
| 2012 |
Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG. P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3. The Journal of Clinical Investigation. 122: 1283-95. PMID 22378045 DOI: 10.1172/Jci38596 |
0.356 |
|
| 2012 |
Yang FH, Zhang B, Zhou DJ, Bie L, Tom MW, Drummond DC, Nicolaides T, Mueller S, Banerjee A, Park JW, Prados MD, James DC, Gupta N, Hashizume R, Strohbehn GW, ... ... Van Meir EG, et al. LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 14: vi25-vi37. DOI: 10.1093/Neuonc/Nos222 |
0.701 |
|
| 2012 |
Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Van Meir EG, ... ... Van Meir EG, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220 |
0.698 |
|
| 2011 |
Mooring SR, Jin H, Devi NS, Jabbar AA, Kaluz S, Liu Y, Van Meir EG, Wang B. Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway. Journal of Medicinal Chemistry. 54: 8471-89. PMID 22032632 DOI: 10.1021/Jm201018G |
0.303 |
|
| 2011 |
Zhu D, Hunter SB, Vertino PM, Van Meir EG. Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1. Cancer Research. 71: 5859-70. PMID 21724586 DOI: 10.1158/0008-5472.Can-11-1157 |
0.331 |
|
| 2011 |
Cork SM, Van Meir EG. Emerging roles for the BAI1 protein family in the regulation of phagocytosis, synaptogenesis, neurovasculature, and tumor development. Journal of Molecular Medicine (Berlin, Germany). 89: 743-52. PMID 21509575 DOI: 10.1007/S00109-011-0759-X |
0.765 |
|
| 2010 |
Klenotic PA, Huang P, Palomo J, Kaur B, Van Meir EG, Vogelbaum MA, Febbraio M, Gladson CL, Silverstein RL. Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. The American Journal of Pathology. 176: 2039-50. PMID 20167858 DOI: 10.2353/Ajpath.2010.090782 |
0.565 |
|
| 2009 |
Hadjipanayis CG, Van Meir EG. Brain cancer propagating cells: biology, genetics and targeted therapies. Trends in Molecular Medicine. 15: 519-30. PMID 19889578 DOI: 10.1016/J.Molmed.2009.09.003 |
0.318 |
|
| 2009 |
Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG. Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. Cancer Research. 69: 1212-20. PMID 19176395 DOI: 10.1158/0008-5472.Can-08-1166 |
0.765 |
|
| 2007 |
Khwaja FW, Reed MS, Olson JJ, Schmotzer BJ, Gillespie GY, Guha A, Groves MD, Kesari S, Pohl J, Van Meir EG. Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. Journal of Proteome Research. 6: 559-70. PMID 17269713 DOI: 10.1021/Pr060240Z |
0.743 |
|
| 2006 |
Belozerov VE, Van Meir EG. Inhibitors of hypoxia-inducible factor-1 signaling. Current Opinion in Investigational Drugs (London, England : 2000). 7: 1067-76. PMID 17209524 |
0.316 |
|
| 2006 |
Kang SH, Cho HT, Devi S, Zhang Z, Escuin D, Liang Z, Mao H, Brat DJ, Olson JJ, Simons JW, Lavallee TM, Giannakakou P, Van Meir EG, Shim H. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Research. 66: 11991-7. PMID 17178898 DOI: 10.1158/0008-5472.Can-06-1320 |
0.324 |
|
| 2006 |
Khwaja FW, Duke-Cohan JS, Brat DJ, Van Meir EG. Attractin is elevated in the cerebrospinal fluid of patients with malignant astrocytoma and mediates glioma cell migration. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6331-6. PMID 17085642 DOI: 10.1158/1078-0432.Ccr-06-1296 |
0.725 |
|
| 2006 |
Khwaja FW, Nolen JD, Mendrinos SE, Lewis MM, Olson JJ, Pohl J, Van Meir EG, Ritchie JC, Brat DJ. Proteomic analysis of cerebrospinal fluid discriminates malignant and nonmalignant disease of the central nervous system and identifies specific protein markers. Proteomics. 6: 6277-87. PMID 17078017 DOI: 10.1002/Pmic.200600135 |
0.712 |
|
| 2006 |
Khwaja FW, Svoboda P, Reed M, Pohl J, Pyrzynska B, Van Meir EG. Proteomic identification of the wt-p53-regulated tumor cell secretome. Oncogene. 25: 7650-61. PMID 17043663 DOI: 10.1038/Sj.Onc.1209969 |
0.755 |
|
| 2006 |
Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. Journal of Neuropathology and Experimental Neurology. 65: 529-39. PMID 16783163 DOI: 10.1097/00005072-200606000-00001 |
0.339 |
|
| 2005 |
Belozerov VE, Van Meir EG. Hypoxia inducible factor-1: a novel target for cancer therapy. Anti-Cancer Drugs. 16: 901-9. PMID 16162966 |
0.312 |
|
| 2005 |
Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG. Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro-Oncology. 7: 134-53. PMID 15831232 DOI: 10.1215/S1152851704001115 |
0.764 |
|
| 2005 |
Kaur B, Brat DJ, Devi NS, Van Meir EG. Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor. Oncogene. 24: 3632-42. PMID 15782143 DOI: 10.1038/Sj.Onc.1208317 |
0.567 |
|
| 2005 |
Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, Zhang H, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KC, Van Meir EG. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway. Cancer Research. 65: 605-12. PMID 15695405 |
0.743 |
|
| 2004 |
Kaur B, Tan C, Brat DJ, Post DE, Van Meir EG. Genetic and hypoxic regulation of angiogenesis in gliomas. Journal of Neuro-Oncology. 70: 229-43. PMID 15674480 DOI: 10.1007/S11060-004-2752-5 |
0.526 |
|
| 2004 |
Post DE, Devi NS, Li Z, Brat DJ, Kaur B, Nicholson A, Olson JJ, Zhang Z, Van Meir EG. Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8603-12. PMID 15623644 DOI: 10.1158/1078-0432.Ccr-04-1432 |
0.556 |
|
| 2004 |
Yang L, Cao Z, Li F, Post DE, Van Meir EG, Zhong H, Wood WC. Tumor-specific gene expression using the survivin promoter is further increased by hypoxia. Gene Therapy. 11: 1215-23. PMID 15141159 DOI: 10.1038/sj.gt.3302280 |
0.337 |
|
| 2004 |
Van Meir EG, Bellail A, Phuphanich S. Emerging molecular therapies for brain tumors. Seminars in Oncology. 31: 38-46. PMID 15124133 |
0.317 |
|
| 2004 |
Brat DJ, Van Meir EG. Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 397-405. PMID 14990981 DOI: 10.1038/Labinvest.3700070 |
0.306 |
|
| 2004 |
Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, Devi SN, Kaur B, Van Meir EG. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Research. 64: 920-7. PMID 14871821 DOI: 10.1158/0008-5472.Can-03-2073 |
0.539 |
|
| 2003 |
Song JH, Song DK, Pyrzynska B, Petruk KC, Van Meir EG, Hao C. TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways. Brain Pathology (Zurich, Switzerland). 13: 539-53. PMID 14655759 DOI: 10.1111/J.1750-3639.2003.Tb00484.X |
0.312 |
|
| 2003 |
Post DE, Van Meir EG. A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy. Oncogene. 22: 2065-72. PMID 12687009 DOI: 10.1038/sj.onc.1206464 |
0.306 |
|
| 2003 |
Kaur B, Brat DJ, Calkins CC, Van Meir EG. Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. The American Journal of Pathology. 162: 19-27. PMID 12507886 DOI: 10.1016/S0002-9440(10)63794-7 |
0.515 |
|
| 2003 |
Brat DJ, Kaur B, Van Meir EG. Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors. Frontiers in Bioscience : a Journal and Virtual Library. 8: d100-16. PMID 12456339 |
0.528 |
|
| 2002 |
Albertoni M, Shaw PH, Nozaki M, Godard S, Tenan M, Hamou MF, Fairlie DW, Breit SN, Paralkar VM, de Tribolet N, Van Meir EG, Hegi ME. Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene. 21: 4212-9. PMID 12082608 DOI: 10.1038/sj.onc.1205610 |
0.332 |
|
| 2002 |
Fulci G, Ishii N, Maurici D, Gernert KM, Hainaut P, Kaur B, Van Meir EG. Initiation of human astrocytoma by clonal evolution of cells with progressive loss of p53 functions in a patient with a 283H TP53 germ-line mutation: evidence for a precursor lesion. Cancer Research. 62: 2897-905. PMID 12019170 |
0.441 |
|
| 2002 |
Mabjeesh NJ, Post DE, Willard MT, Kaur B, Van Meir EG, Simons JW, Zhong H. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Research. 62: 2478-82. PMID 11980636 |
0.459 |
|
| 2002 |
Brat DJ, Castellano-Sanchez A, Kaur B, Van Meir EG. Genetic and biologic progression in astrocytomas and their relation to angiogenic dysregulation. Advances in Anatomic Pathology. 9: 24-36. PMID 11756757 DOI: 10.1097/00125480-200201000-00004 |
0.473 |
|
| 1996 |
Van Meir EG. Cytokines and tumors of the central nervous system. Glia. 15: 264-88. PMID 8586463 DOI: 10.1002/glia.440150308 |
0.349 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2009 |
Hadjipanayis CG, Van Meir EG. Tumor initiating cells in malignant gliomas: biology and implications for therapy. Journal of Molecular Medicine (Berlin, Germany). 87: 363-74. PMID 19189072 DOI: 10.1007/s00109-009-0440-9 |
0.295 |
|
| 2003 |
Cobbs CS, Whisenhunt TR, Wesemann DR, Harkins LE, Van Meir EG, Samanta M. Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells. Cancer Research. 63: 8670-3. PMID 14695179 |
0.295 |
|
| 2013 |
Burroughs SK, Kaluz S, Wang D, Wang K, Van Meir EG, Wang B. Hypoxia inducible factor pathway inhibitors as anticancer therapeutics. Future Medicinal Chemistry. 5: 553-72. PMID 23573973 DOI: 10.4155/Fmc.13.17 |
0.294 |
|
| 2017 |
Ng TFF, Dill JA, Camus AC, Delwart E, Van Meir EG. Two new species of betatorqueviruses identified in a human melanoma that metastasized to the brain. Oncotarget. 8: 105800-105808. PMID 29285293 DOI: 10.18632/oncotarget.22400 |
0.294 |
|
| 2004 |
Bellail AC, Hunter SB, Brat DJ, Tan C, Van Meir EG. Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. The International Journal of Biochemistry & Cell Biology. 36: 1046-69. PMID 15094120 DOI: 10.1016/J.Biocel.2004.01.013 |
0.293 |
|
| 2012 |
Nduom EK, Hadjipanayis CG, Van Meir EG. Glioblastoma cancer stem-like cells: implications for pathogenesis and treatment. Cancer Journal (Sudbury, Mass.). 18: 100-6. PMID 22290263 DOI: 10.1097/PPO.0b013e3182452e0d |
0.293 |
|
| 2010 |
Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, Wen PY, Olson JJ. Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. Ca: a Cancer Journal For Clinicians. 60: 166-93. PMID 20445000 DOI: 10.3322/Caac.20069 |
0.292 |
|
| 2006 |
Li YC, Tzeng CC, Song JH, Tsia FJ, Hsieh LJ, Liao SJ, Tsai CH, Van Meir EG, Hao C, Lin CC. Genomic alterations in human malignant glioma cells associate with the cell resistance to the combination treatment with tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2716-29. PMID 16675563 DOI: 10.1158/1078-0432.Ccr-05-1980 |
0.292 |
|
| 2009 |
Narita T, Yin S, Gelin CF, Moreno CS, Yepes M, Nicolaou KC, Van Meir EG. Identification of a novel small molecule HIF-1alpha translation inhibitor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6128-36. PMID 19789328 DOI: 10.1158/1078-0432.Ccr-08-3180 |
0.289 |
|
| 2004 |
Chu RL, Post DE, Khuri FR, Van Meir EG. Use of replicating oncolytic adenoviruses in combination therapy for cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5299-312. PMID 15328165 DOI: 10.1158/1078-0432.CCR-0349-03 |
0.289 |
|
| 2005 |
Rong Y, Post DE, Pieper RO, Durden DL, Van Meir EG, Brat DJ. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Research. 65: 1406-13. PMID 15735028 DOI: 10.1158/0008-5472.Can-04-3376 |
0.288 |
|
| 2004 |
Post DE, Fulci G, Chiocca EA, Van Meir EG. Replicative oncolytic herpes simplex viruses in combination cancer therapies. Current Gene Therapy. 4: 41-51. PMID 15032613 DOI: 10.2174/1566523044577988 |
0.284 |
|
| 2022 |
Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, ... ... Van Meir EG, et al. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. PMID 35649412 DOI: 10.1016/j.cell.2022.04.038 |
0.282 |
|
| 2008 |
Ventii KH, Devi NS, Friedrich KL, Chernova TA, Tighiouart M, Van Meir EG, Wilkinson KD. BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization. Cancer Research. 68: 6953-62. PMID 18757409 DOI: 10.1158/0008-5472.Can-08-0365 |
0.279 |
|
| 2008 |
Kim H, Peng G, Hicks JM, Weiss HL, Van Meir EG, Brenner MK, Yotnda P. Engineering human tumor-specific cytotoxic T cells to function in a hypoxic environment. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 599-606. PMID 18227840 DOI: 10.1038/sj.mt.6300391 |
0.277 |
|
| 2021 |
Kaluz S, Zhang Q, Kuranaga Y, Yang H, Osuka S, Bhattacharya D, Devi NS, Mun J, Wang W, Zhang R, Goodman MM, Grossniklaus HE, Van Meir EG. Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth. Oncogene. PMID 34218269 DOI: 10.1038/s41388-021-01919-x |
0.277 |
|
| 2014 |
Chen G, Kong J, Tucker-Burden C, Anand M, Rong Y, Rahman F, Moreno CS, Van Meir EG, Hadjipanayis CG, Brat DJ. Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma. Cancer Research. 74: 4536-48. PMID 24947043 DOI: 10.1158/0008-5472.Can-13-3703 |
0.27 |
|
| 2017 |
Osuka S, Van Meir EG. Overcoming therapeutic resistance in glioblastoma: the way forward. The Journal of Clinical Investigation. 127: 415-426. PMID 28145904 DOI: 10.1172/JCI89587 |
0.27 |
|
| 2018 |
Van Meir EG, Dong L, You S, Zhang Q, Osuka S, Devi NS, Kaluz S, Holmes JN, Yang H, Chen G, Wang B, Grossniklaus HE. Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30563937 DOI: 10.1158/1078-0432.Ccr-18-1368 |
0.267 |
|
| 2017 |
Dai X, Kaluz S, Jiang Y, Shi L, Mckinley D, Wang Y, Wang B, Van Meir EG, Tan C. A novel small-molecule arylsulfonamide causes energetic stress and suppresses breast and lung tumor growth and metastasis. Oncotarget. 8: 99245-99260. PMID 29245898 DOI: 10.18632/Oncotarget.22104 |
0.266 |
|
| 2003 |
Hunter SB, Brat DJ, Olson JJ, Von Deimling A, Zhou W, Van Meir EG. Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review). International Journal of Oncology. 23: 857-69. PMID 12963964 DOI: 10.3892/Ijo.23.4.857 |
0.266 |
|
| 2004 |
Landen JW, Hau V, Wang M, Davis T, Ciliax B, Wainer BH, Van Meir EG, Glass JD, Joshi HC, Archer DR. Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5187-201. PMID 15297423 DOI: 10.1158/1078-0432.Ccr-04-0360 |
0.265 |
|
| 2002 |
Kragh M, Quistorff B, Tenan M, Van Meir EG, Kristjansen PE. Overexpression of thrombospondin-1 reduces growth and vascular index but not perfusion in glioblastoma. Cancer Research. 62: 1191-5. PMID 11861403 |
0.264 |
|
| 2021 |
Skowron P, Farooq H, Cavalli FMG, Morrissy AS, Ly M, Hendrikse LD, Wang EY, Djambazian H, Zhu H, Mungall KL, Trinh QM, Zheng T, Dai S, Stucklin ASG, Vladoiu MC, ... ... Van Meir EG, et al. The transcriptional landscape of Shh medulloblastoma. Nature Communications. 12: 1749. PMID 33741928 DOI: 10.1038/s41467-021-21883-0 |
0.261 |
|
| 2023 |
Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed WR, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, ... ... Van Meir EG, et al. The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen. Cancer Research. PMID 38117484 DOI: 10.1158/0008-5472.CAN-23-2093 |
0.261 |
|
| 1999 |
Fulci G, Van Meir EG. p53 and the CNS: tumors and developmental abnormalities. Molecular Neurobiology. 19: 61-77. PMID 10321972 DOI: 10.1007/BF02741378 |
0.259 |
|
| 2011 |
Tan C, de Noronha RG, Devi NS, Jabbar AA, Kaluz S, Liu Y, Mooring SR, Nicolaou KC, Wang B, Van Meir EG. Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 5528-32. PMID 21831638 DOI: 10.1016/J.Bmcl.2011.06.099 |
0.257 |
|
| 2017 |
Ferguson J, De Los Santos Z, Devi N, Van Meir E, Zingales S, Wang B. Examining the structure-activity relationship of benzopyran-based inhibitors of the hypoxia inducible factor-1 pathway. Bioorganic & Medicinal Chemistry Letters. PMID 28285917 DOI: 10.1016/J.Bmcl.2017.02.073 |
0.256 |
|
| 2015 |
Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, et al. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Research. 25: 316-27. PMID 25650244 DOI: 10.1101/Gr.180612.114 |
0.256 |
|
| 2021 |
Osuka S, Zhu D, Zhang Z, Li C, Stackhouse CT, Sampetrean O, Olson JJ, Gillespie GY, Saya H, Willey CD, Van Meir EG. N-cadherin upregulation mediates adaptive radioresistance in glioblastoma. The Journal of Clinical Investigation. 131. PMID 33720050 DOI: 10.1172/JCI136098 |
0.255 |
|
| 2011 |
Kalinina J, Peng J, Ritchie JC, Van Meir EG. Proteomics of gliomas: initial biomarker discovery and evolution of technology. Neuro-Oncology. 13: 926-42. PMID 21852429 DOI: 10.1093/Neuonc/Nor078 |
0.251 |
|
| 2018 |
Osuka S, Yang L, Zhu D, Devi N, Van Meir E. ANGI-14. EPIGENETIC REACTIVATION OF BAI1 SUPPRESSES TUMOR INVASION BY PREVENTING TGFβ1-INDUCED MESENCHYMAL SWITCH IN GLIOBLASTOMA Neuro-Oncology. 20: vi31-vi31. DOI: 10.1093/neuonc/noy148.115 |
0.25 |
|
| 2021 |
Kim H, Kang Y, Li Y, Chen L, Lin L, Johnson ND, Zhu D, Robinson MH, McSwain L, Barwick BG, Yuan X, Liao X, Zhao J, Zhang Z, Shu Q, ... ... Van Meir EG, et al. Ten-eleven translocation protein 1 modulates medulloblastoma progression. Genome Biology. 22: 125. PMID 33926529 DOI: 10.1186/s13059-021-02352-9 |
0.248 |
|
| 2011 |
Zerrouqi A, Van Meir EG. A conspiracy of glioma and endothelial cells to invade the normal brain. Oncotarget. 2: 1-4. PMID 21378411 DOI: 10.18632/oncotarget.219 |
0.239 |
|
| 1999 |
Ishii N, Tada M, Hamou MF, Janzer RC, Meagher-Villemure K, Wiestler OD, Tribolet N, Van Meir EG. Cells with TP53 mutations in low grade astrocytic tumors evolve clonally to malignancy and are an unfavorable prognostic factor. Oncogene. 18: 5870-8. PMID 10557074 DOI: 10.1038/sj.onc.1203241 |
0.237 |
|
| 2019 |
Zhang H, Zhu D, Zhang Z, Kaluz S, Yu B, Devi NS, Olson JJ, Van Meir EG. Correction: EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway. Oncogene. PMID 31676871 DOI: 10.1038/s41388-019-1067-0 |
0.235 |
|
| 2009 |
Rong Y, Belozerov VE, Tucker-Burden C, Chen G, Durden DL, Olson JJ, Van Meir EG, Mackman N, Brat DJ. Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity. Cancer Research. 69: 2540-9. PMID 19276385 DOI: 10.1158/0008-5472.Can-08-1547 |
0.234 |
|
| 2007 |
Post DE, Sandberg EM, Kyle MM, Devi NS, Brat DJ, Xu Z, Tighiouart M, Van Meir EG. Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4. Cancer Research. 67: 6872-81. PMID 17638898 DOI: 10.1158/0008-5472.Can-06-3244 |
0.234 |
|
| 2014 |
Fan J, Shan C, Kang HB, Elf S, Xie J, Tucker M, Gu TL, Aguiar M, Lonning S, Chen H, Mohammadi M, Britton LM, Garcia BA, AleÄković M, Kang Y, ... ... Van Meir EG, et al. Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Molecular Cell. 53: 534-48. PMID 24486017 DOI: 10.1016/J.Molcel.2013.12.026 |
0.231 |
|
| 2004 |
Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM. Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. The American Journal of Pathology. 165: 1151-61. PMID 15466382 DOI: 10.1016/S0002-9440(10)63376-7 |
0.231 |
|
| 1995 |
Van Meir E, de Tribolet N. Microsatellite Instability in Human Brain Tumors Neurosurgery. 37: 1231???1232. DOI: 10.1097/00006123-199512000-00035 |
0.227 |
|
| 2016 |
Okura H, Golbourn BJ, Shahzad U, Agnihotri S, Sabha N, Krieger JR, Figueiredo CA, Chalil A, Landon-Brace N, Riemenschneider A, Arai H, Smith CA, Xu S, Kaluz S, Marcus AI, ... Van Meir EG, et al. A role for activated Cdc42 in glioblastoma multiforme invasion. Oncotarget. PMID 27486972 DOI: 10.18632/Oncotarget.10925 |
0.226 |
|
| 1994 |
Van Meir EG, Polverini PJ, Chazin VR, Huang HJS, De Tribolet N, Cavenee WK. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells Nature Genetics. 8: 171-176. PMID 7531056 DOI: 10.1038/ng1094-171 |
0.226 |
|
| 2003 |
Kim E, Günther W, Yoshizato K, Meissner H, Zapf S, Nüsing RM, Yamamoto H, Van Meir EG, Deppert W, Giese A. Tumor suppressor p53 inhibits transcriptional activation of invasion gene thromboxane synthase mediated by the proto-oncogenic factor ets-1. Oncogene. 22: 7716-27. PMID 14586398 DOI: 10.1038/sj.onc.1207155 |
0.222 |
|
| 2014 |
Kim H, Zheng S, Amini S, Virk S, Mikkelsen T, Brat D, Sougnez C, Muller F, Hu J, Sloan A, Cohen M, Van Meir E, Scarpace L, Lander E, Gabriel S, et al. GE-17 * ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: v100-v100. DOI: 10.1093/Neuonc/Nou256.17 |
0.219 |
|
| 2016 |
Zhu D, Reichert Z, Nelson W, Olson J, Van Meir E. MB-05BAI1 IS A TUMOR SUPPRESSOR IN MEDULLOBLASTOMA Neuro-Oncology. 18: iii98.1-iii98. DOI: 10.1093/Neuonc/Now076.05 |
0.219 |
|
| 2006 |
Rong Y, Hu F, Huang R, Mackman N, Horowitz JM, Jensen RL, Durden DL, Van Meir EG, Brat DJ. Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Research. 66: 7067-74. PMID 16849552 DOI: 10.1158/0008-5472.Can-06-0346 |
0.218 |
|
| 2001 |
Labuhn M, Jones G, Speel EJ, Maier D, Zweifel C, Gratzl O, Van Meir EG, Hegi ME, Merlo A. Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas. Oncogene. 20: 1103-9. PMID 11314047 DOI: 10.1038/sj.onc.1204197 |
0.216 |
|
| 2005 |
Post DE, Shim H, Toussaint-Smith E, Van Meir EG. Cancer scene investigation: how a cold virus became a tumor killer. Future Oncology (London, England). 1: 247-58. PMID 16555996 DOI: 10.1517/14796694.1.2.247 |
0.215 |
|
| 1999 |
Desbaillets I, Diserens AC, de Tribolet N, Hamou MF, Van Meir EG. Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma. Oncogene. 18: 1447-56. PMID 10050881 DOI: 10.1038/sj.onc.1202424 |
0.214 |
|
| 2014 |
Verhaak RGW, Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, et al. THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: iii3-iii3. DOI: 10.1093/Neuonc/Nou206.10 |
0.212 |
|
| 1997 |
Van Meir E. Hypoxia-mediated selection of cells with diminished apoptotic potential to solid tumours. Neurosurgery. 39: 878-9. PMID 8880787 DOI: 10.1097/00006123-199610000-00057 |
0.212 |
|
| 2010 |
Doucette TA, Kong L, Yang Y, Wei J, Wang J, Fuller GN, Heimberger AB, Rao G, Ajewung N, Kamnasaran D, Katz AM, Amankulor N, Squatrito M, Hambardzumyan D, Holland EC, ... ... Van Meir E, et al. Tumor Models (In Vivo/In Vitro) Neuro-Oncology. 12: iv130-iv136. DOI: 10.1093/Neuonc/Noq116.S20 |
0.203 |
|
| 2023 |
Shiu FH, Wong JC, Bhattacharya D, Kuranaga Y, Parag RR, Alsharif HA, Bhatnagar S, Van Meir EG, Escayg A. Generation and initial characterization of mice lacking full length BAI3 (ADGRB3) expression. Basic & Clinical Pharmacology & Toxicology. PMID 37337931 DOI: 10.1111/bcpt.13917 |
0.201 |
|
| 2013 |
Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Van Meir EG, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034 |
0.201 |
|
| 2004 |
Koivisto PA, Zhang X, Sallinen SL, Sallinen P, Helin HJ, Dong JT, Van Meir EG, Haapasalo H, Hyytinen ER. Absence of KLF6 gene mutations in human astrocytic tumors and cell lines. International Journal of Cancer. 111: 642-3. PMID 15239146 DOI: 10.1002/ijc.20301 |
0.196 |
|
| 2017 |
Ferguson JH, De Los Santos Z, Devi SN, Kaluz S, Van Meir EG, Zingales SK, Wang B. Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility. Journal of Enzyme Inhibition and Medicinal Chemistry. 32: 992-1001. PMID 28766956 DOI: 10.1080/14756366.2017.1347784 |
0.196 |
|
| 2014 |
Zhu D, Zhang Z, Olson J, Van Meir E. CS-38 * BAI1 IS A NEW TUMOR SUPPRESSOR IN MEDULLOBLASTOMA Neuro-Oncology. 16: v59-v59. DOI: 10.1093/neuonc/nou242.38 |
0.195 |
|
| 2012 |
Cooper LA, Gutman DA, Chisolm C, Appin C, Kong J, Rong Y, Kurc T, Van Meir EG, Saltz JH, Moreno CS, Brat DJ. The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. The American Journal of Pathology. 180: 2108-19. PMID 22440258 DOI: 10.1016/J.Ajpath.2012.01.040 |
0.191 |
|
| 2012 |
Wang W, Ao L, Rayburn ER, Xu H, Zhang X, Zhang X, Nag SA, Wu X, Wang MH, Wang H, Van Meir EG, Zhang R. KCN1, a novel synthetic sulfonamide anticancer agent: in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. Plos One. 7: e44883. PMID 23028659 DOI: 10.1371/journal.pone.0044883 |
0.19 |
|
| 2012 |
Kalinina J, Carroll A, Wang L, Yu Q, Mancheno DE, Wu S, Liu F, Ahn J, He M, Mao H, Van Meir EG. Detection of "oncometabolite" 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma. Journal of Molecular Medicine (Berlin, Germany). 90: 1161-71. PMID 22426639 DOI: 10.1007/S00109-012-0888-X |
0.189 |
|
| 2020 |
Van Meir EG, Lee SH, Rehman FK, Tyler KC, Yu B, Zhang Z, Zerrouqi A, Kaluzova M, Hadjipanayis CG, Cummings RD, Olson JJ, Devi NS, Osuka S. A Chimeric Signal Peptide-Galectin-3 Conjugate Induces Glycosylation-Dependent Cancer Cell-Specific Apoptosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31969339 DOI: 10.1158/1078-0432.CCR-18-3280 |
0.189 |
|
| 2012 |
Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Van Meir EG, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327 |
0.187 |
|
| 1998 |
Van Meir EG. "Turcot's syndrome": phenotype of brain tumors, survival and mode of inheritance. International Journal of Cancer. 75: 162-4. PMID 9426707 DOI: 10.1002/(SICI)1097-0215(19980105)75:1<162::AID-IJC26>3.0.CO;2-H |
0.181 |
|
| 2022 |
Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, ... ... Van Meir EG, et al. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. PMID 36131014 DOI: 10.1038/s41586-022-05215-w |
0.181 |
|
| 2014 |
Zhukova N, Ramaswamy V, Remke M, Martin DC, Castelo-Branco P, Zhang CH, Fraser M, Tse K, Poon R, Shih DJ, Baskin B, Ray PN, Bouffet E, Dirks P, von Bueren AO, ... ... Van Meir EG, et al. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathologica Communications. 2: 174. PMID 25539912 DOI: 10.1186/S40478-014-0174-Y |
0.177 |
|
| 1997 |
Saas P, Walker P, Hahne M, Quiquerez A, Schnuriger V, Perrin G, French L, Van Meir E, de Tribolet N, Tschopp J, Dietrich P. Is Fas ligand (CD95L) expression by astrocytoma cells a major mechanism of inactivation of tumour infiltrating lymphocytes? Immunology Letters. 56: 435. DOI: 10.1016/S0165-2478(97)86766-1 |
0.177 |
|
| 2018 |
Zhu D, Osuka S, Zhang Z, Reichert Z, Kanemura Y, Nishikawa R, G. Nelson W, J. Olson J, Van Meir EG. PDTM-27. EPIGENETIC LOSS OF BAI1 EXPRESSION IN CEREBELLAR GRANULE NEURON PRECURSORS INACTIVATES THE p53 TUMOR SUPPRESSOR AND FACILITATES MEDULLOBLASTOMA FORMATION IN THE CEREBELLUM Neuro-Oncology. 20: vi209-vi209. DOI: 10.1093/neuonc/noy148.868 |
0.173 |
|
| 2012 |
Mun J, Jabbar AA, Devi NS, Yin S, Wang Y, Tan C, Culver D, Snyder JP, Van Meir EG, Goodman MM. Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents. Journal of Medicinal Chemistry. 55: 6738-50. PMID 22746274 DOI: 10.1021/Jm300752N |
0.17 |
|
| 2018 |
Davare MA, Henderson JJ, Agarwal A, Wagner JP, Iyer SR, Shah N, Woltjer R, Somwar R, Gilheeney SW, deCarvalho AC, Mikkelsen T, Van Meir EG, Ladanyi M, Druker BJ. Rare but recurrent ROS1 fusions resulting from chromosome 6q22 microdeletions are targetable oncogenes in glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30171048 DOI: 10.1158/1078-0432.Ccr-18-1052 |
0.168 |
|
| 2019 |
Morgan RK, Anderson GR, Araç D, Aust G, Balenga N, Boucard A, Bridges JP, Engel FB, Formstone CJ, Glitsch MD, Gray RS, Hall RA, Hsiao CC, Kim HY, Knierim AB, ... ... Van Meir EG, et al. The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors. Annals of the New York Academy of Sciences. PMID 31168816 DOI: 10.1111/Nyas.14094 |
0.168 |
|
| 2022 |
Shiu FH, Wong JC, Yamamoto T, Lala T, Purcell RH, Owino S, Zhu D, Van Meir EG, Hall RA, Escayg A. Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development. Experimental Neurology. 113994. PMID 35114205 DOI: 10.1016/j.expneurol.2022.113994 |
0.165 |
|
| 2004 |
Ahn JY, Rong R, Kroll TG, Van Meir EG, Snyder SH, Ye K. PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion. The Journal of Biological Chemistry. 279: 16441-51. PMID 14761976 DOI: 10.1074/jbc.M312175200 |
0.165 |
|
| 2017 |
Kim YJ, Kaluz S, Mehta A, Weinert E, Rivera S, Van Meir EG. Purifying Properly Folded Cysteine-rich, Zinc Finger Containing Recombinant Proteins for Structural Drug Targeting Studies: the CH1 Domain of p300 as a Case Example. Bio-Protocol. 7. PMID 28966947 DOI: 10.21769/BioProtoc.2537 |
0.164 |
|
| 2019 |
Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, ... ... Van Meir EG, et al. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. PMID 31748746 DOI: 10.1038/S41586-019-1775-1 |
0.162 |
|
| 2011 |
Kong J, Cooper LA, Wang F, Gutman DA, Gao J, Chisolm C, Sharma A, Pan T, Van Meir EG, Kurc TM, Moreno CS, Saltz JH, Brat DJ. Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes. Ieee Transactions On Bio-Medical Engineering. 58: 3469-74. PMID 21947516 DOI: 10.1109/Tbme.2011.2169256 |
0.162 |
|
| 2021 |
Snyder JM, Huang RY, Bai H, Rao VR, Cornes S, Barnholtz-Sloan JS, Gutman D, Fasano R, Van Meir EG, Brat D, Eschbacher J, Quackenbush J, Wen PY, Lee JW. Analysis of morphological characteristics of IDH-mutant/wildtype brain tumors using whole-lesion phenotype analysis. Neuro-Oncology Advances. 3: vdab088. PMID 34409295 DOI: 10.1093/noajnl/vdab088 |
0.16 |
|
| 2010 |
Cooper LA, Kong J, Gutman DA, Wang F, Cholleti SR, Pan TC, Widener PM, Sharma A, Mikkelsen T, Flanders AE, Rubin DL, Van Meir EG, Kurc TM, Moreno CS, Brat DJ, et al. An integrative approach for in silico glioma research. Ieee Transactions On Bio-Medical Engineering. 57: 2617-21. PMID 20656651 DOI: 10.1109/Tbme.2010.2060338 |
0.157 |
|
| 2008 |
McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis GM, Olson JJ, Mikkelsen T, Lehman N, Aldape K, Yung WKA, Bogler O, Weinstein JN, VandenBerg S, Berger M, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature. 455: 1061-1068. PMID 18772890 DOI: 10.1038/Nature07385 |
0.156 |
|
| 1998 |
Maier D, Zhang Z, Taylor E, Hamou MF, Gratzl O, Van Meir EG, Scott RJ, Merlo A. Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas. Oncogene. 16: 3331-5. PMID 9681833 DOI: 10.1038/sj.onc.1201832 |
0.156 |
|
| 2012 |
Shi Q, Yin S, Kaluz S, Ni N, Devi NS, Mun J, Wang D, Damera K, Chen W, Burroughs S, Mooring SR, Goodman MM, Van Meir EG, Wang B, Snyder JP. Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor. Acs Medicinal Chemistry Letters. 3: 620-5. PMID 24936238 DOI: 10.1021/Ml300042K |
0.153 |
|
| 2012 |
Mun J, Jabbar AA, Devi NS, Liu Y, Van Meir EG, Goodman MM. Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent. Bioorganic & Medicinal Chemistry. 20: 4590-7. PMID 22682301 DOI: 10.1016/j.bmc.2012.04.064 |
0.153 |
|
| 2007 |
Boulay JL, Miserez AR, Zweifel C, Sivasankaran B, Kana V, Ghaffari A, Luyken C, Sabel M, Zerrouqi A, Wasner M, Van Meir E, Tolnay M, Reifenberger G, Merlo A. Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors. Plos One. 2: e576. PMID 17593975 DOI: 10.1371/Journal.Pone.0000576 |
0.153 |
|
| 2000 |
Fulci G, Labuhn M, Maier D, Lachat Y, Hausmann O, Hegi ME, Janzer RC, Merlo A, Van Meir EG. p53 gene mutation and ink4a-arf deletion appear to be two mutually exclusive events in human glioblastoma. Oncogene. 19: 3816-22. PMID 10949938 DOI: 10.1038/sj.onc.1203700 |
0.153 |
|
| 2015 |
Luke JJ, Triozzi PL, McKenna KC, Van Meir EG, Gershenwald JE, Bastian BC, Gutkind JS, Bowcock AM, Streicher HZ, Patel PM, Sato T, Sossman JA, Sznol M, Welch J, Thurin M, et al. Biology of advanced uveal melanoma and next steps for clinical therapeutics. Pigment Cell & Melanoma Research. 28: 135-47. PMID 25113308 DOI: 10.1111/Pcmr.12304 |
0.152 |
|
| 2013 |
Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Van Meir EG, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174 |
0.144 |
|
| 2002 |
Bratt A, Wilson WJ, Troyanovsky B, Aase K, Kessler R, Van Meir EG, Holmgren L, Meir EG. Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains. Gene. 298: 69-77. PMID 12406577 DOI: 10.1016/S0378-1119(02)00928-9 |
0.142 |
|
| 2013 |
Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, ... ... Van Meir EG, et al. Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2927-35. PMID 23835706 DOI: 10.1200/Jco.2012.48.5052 |
0.14 |
|
| 2015 |
Zhu D, Li C, Swanson AM, Villalba RM, Guo J, Zhang Z, Matheny S, Murakami T, Stephenson JR, Daniel S, Fukata M, Hall RA, Olson JJ, Neigh GN, Smith Y, ... ... Van Meir EG, et al. BAI1 regulates spatial learning and synaptic plasticity in the hippocampus. The Journal of Clinical Investigation. 125: 1497-508. PMID 25751059 DOI: 10.1172/Jci74603 |
0.14 |
|
| 2016 |
Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, ... ... Van Meir EG, et al. Divergent clonal selection dominates medulloblastoma at recurrence. Nature. PMID 26760213 DOI: 10.1038/Nature16478 |
0.138 |
|
| 2005 |
Brat DJ, Bellail AC, Van Meir EG. The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro-Oncology. 7: 122-33. PMID 15831231 DOI: 10.1215/S1152851704001061 |
0.137 |
|
| 2009 |
Dasgupta A, Raychaudhuri B, Haqqi T, Prayson R, Van Meir EG, Vogelbaum M, Haque SJ. Stat3 activation is required for the growth of U87 cell-derived tumours in mice. European Journal of Cancer (Oxford, England : 1990). 45: 677-84. PMID 19121577 DOI: 10.1016/j.ejca.2008.11.027 |
0.133 |
|
| 1989 |
Van Meir E, Wittek R. Fine structure of the vaccinia virus gene encoding the precursor of the major core protein 4 a. Archives of Virology. 102: 19-27. PMID 3196167 DOI: 10.1007/BF01315559 |
0.126 |
|
| 1998 |
Albertoni M, Daub DM, Arden KC, Viars CS, Powell C, Van Meir EG. Genetic instability leads to loss of both p53 alleles in a human glioblastoma. Oncogene. 16: 321-6. PMID 9467957 DOI: 10.1038/sj.onc.1201544 |
0.123 |
|
| 2005 |
Nicholson AC, Malik SB, Logsdon JM, Van Meir EG. Functional evolution of ADAMTS genes: evidence from analyses of phylogeny and gene organization. Bmc Evolutionary Biology. 5: 11. PMID 15693998 DOI: 10.1186/1471-2148-5-11 |
0.12 |
|
| 2020 |
Nobre L, Zapotocky M, Khan S, Fukuoka K, Fonseca A, McKeown T, Sumerauer D, Vicha A, Grajkowska WA, Trubicka J, Li KKW, Ng HK, Massimi L, Lee JY, Kim SK, ... ... Van Meir EG, et al. Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma. Cell Reports. Medicine. 1. PMID 32743560 DOI: 10.1016/j.xcrm.2020.100038 |
0.119 |
|
| 1993 |
Abrahamsen TG, Wesenberg F, Mørk S, Allen J, Hayes R, DaRosso R, Nirenberg A, Ali-Osman F, Akande N, Amberger V, Seulberger H, Paganetti PA, Schwab ME, Schwab ME, Arita N, ... ... Van Meir E, ... ... Van Meir E, et al. Abstracts for the Tenth International Conference on Brain Tumour Research and Therapy Journal of Neuro-Oncology. 15: S1-S30. DOI: 10.1007/Bf02041900 |
0.117 |
|
| 1993 |
Tada M, Suzuki K, Yamakawa Y, Sawamura Y, Sakuma S, Abe H, van Meir E, de Tribolet N. Human glioblastoma cells produce 77 amino acid interleukin-8 (IL-8(77)). Journal of Neuro-Oncology. 16: 25-34. PMID 8410139 DOI: 10.1007/BF01324831 |
0.114 |
|
| 2013 |
Remke M, Ramaswamy V, Peacock J, Shih DJ, Koelsche C, Northcott PA, Hill N, Cavalli FM, Kool M, Wang X, Mack SC, Barszczyk M, Morrissy AS, Wu X, Agnihotri S, ... ... Van Meir EG, et al. TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathologica. 126: 917-29. PMID 24174164 DOI: 10.1007/S00401-013-1198-2 |
0.11 |
|
| 1991 |
DE TAVORA A, VAN MEIR E, MIRIMANOFF R, DE TRIBOLET N, RUTZ H. Effects of Antisense DNA Oligonucleotides of Lactate Dehydrogenase and Glucose-6-Phosphate Dehydrogenase Genes on Proliferation of Confluent Cultures of U251 Glioblastoma Cells Antisense Research and Development. 1: 381-381. DOI: 10.1089/ard.1991.1.381 |
0.103 |
|
| 2018 |
Van Meir E, Olson J, Zhu D, Osuka S, Zhang Z. CADD-26. SMALL MOLECULE EPIGENETIC TARGETING OF METHYL-CPG BINDING PROTEIN 2 (MBD2) FOR MEDULLOBLASTOMA THERAPY Neuro-Oncology. 20: vi280-vi280. DOI: 10.1093/neuonc/noy148.1167 |
0.103 |
|
| 2016 |
Kalinina J, Ahn J, Devi NS, Wang L, Li Y, Olson JJ, Glantz M, Smith T, Kim E, Giese A, Jensen RL, Chen C, Carter B, Mao H, He M, ... Van Meir EG, et al. Selective detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of glioma patients with mutated Isocitrate Dehydrogenase. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27340277 DOI: 10.1158/1078-0432.Ccr-15-2965 |
0.1 |
|
| 1997 |
Maier D, Comparone D, Taylor E, Zhang Z, Gratzl O, Van Meir EG, Scott RJ, Merlo A. New deletion in low-grade oligodendroglioma at the glioblastoma suppressor locus on chromosome 10q25-26. Oncogene. 15: 997-1000. PMID 9285695 DOI: 10.1038/sj.onc.1201209 |
0.099 |
|
| 2021 |
Coltin H, Sundaresan L, Smith KS, Skowron P, Massimi L, Eberhart CG, Schreck KC, Gupta N, Weiss WA, Tirapelli D, Carlotti C, Li KKW, Ryzhova M, Golanov A, Zheludkova O, ... ... Van Meir EG, et al. Subgroup and subtype-specific outcomes in adult medulloblastoma. Acta Neuropathologica. PMID 34409497 DOI: 10.1007/s00401-021-02358-4 |
0.095 |
|
| 2003 |
Bratt A, Wilson WJ, Troyanovsky B, Aase K, Kessler R, Van Meir EG, Holmgren L. Corrigendum to “Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains” [Gene 298 (2002) 69–77] Gene. 310: 221. DOI: 10.1016/S0378-1119(03)00524-9 |
0.094 |
|
| 2019 |
Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, ... ... Van Meir EG, et al. Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma. Nature. PMID 31597162 DOI: 10.1038/s41586-019-1650-0 |
0.094 |
|
| 2014 |
Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, ... ... Van Meir EG, et al. Cytogenetic prognostication within medulloblastoma subgroups. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 886-96. PMID 24493713 DOI: 10.1200/Jco.2013.50.9539 |
0.093 |
|
| 2015 |
Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Van Meir EG, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121 |
0.091 |
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| 2017 |
Cavalli FMG, Remke M, Rampasek L, Peacock J, Shih DJH, Luu B, Garzia L, Torchia J, Nor C, Morrissy AS, Agnihotri S, Thompson YY, Kuzan-Fischer CM, Farooq H, Isaev K, ... ... Van Meir EG, et al. Intertumoral Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 31: 737-754.e6. PMID 28609654 DOI: 10.1016/J.Ccell.2017.05.005 |
0.087 |
|
| 2016 |
Zhu D, Van Meir EG. BAI1: from cancer to neurological disease. Oncotarget. PMID 27008705 DOI: 10.18632/oncotarget.8193 |
0.087 |
|
| 2010 |
Iskow RC, McCabe MT, Mills RE, Torene S, Pittard WS, Neuwald AF, Van Meir EG, Vertino PM, Devine SE. Natural mutagenesis of human genomes by endogenous retrotransposons. Cell. 141: 1253-61. PMID 20603005 DOI: 10.1016/J.Cell.2010.05.020 |
0.086 |
|
| 2018 |
Verhaak R, Consortium G, Aldape K, Amin S, Ashley D, Barnholtz-Sloan J, Bates A, Beroukhim R, Bock C, Brat D, Claus E, Costello J, de Groot J, Finocchiaro G, French P, ... ... Van Meir E, et al. DRES-05. MOLECULAR EVOLUTION OF DIFFUSE GLIOMAS AND THE GLIOMA LONGITUDINAL ANALYSIS CONSORTIUM Neuro-Oncology. 20: vi76-vi76. DOI: 10.1093/Neuonc/Noy148.312 |
0.085 |
|
| 2019 |
Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, ... ... Van Meir EG, et al. Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma. Nature. 574: 707-711. PMID 31664194 DOI: 10.1038/S41586-019-1650-0 |
0.085 |
|
| 2019 |
Grossniklaus HE, Van Meir EG. Are Risk Factors for Growth of Choroidal Nevi Associated With Malignant Transformation? Assessment With a Validated Genomic Biomarker. American Journal of Ophthalmology. PMID 31109628 DOI: 10.1016/j.ajo.2019.01.033 |
0.084 |
|
| 2019 |
Bhattacharya D, Van Meir EG. A simple genotyping method to detect small CRISPR-Cas9 induced indels by agarose gel electrophoresis. Scientific Reports. 9: 4437. PMID 30872606 DOI: 10.1038/s41598-019-39950-4 |
0.083 |
|
| 2013 |
Akers JC, Ramakrishnan V, Kim R, Skog J, Nakano I, Pingle S, Kalinina J, Hua W, Kesari S, Mao Y, Breakefield XO, Hochberg FH, Van Meir EG, Carter BS, Chen CC. MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development. Plos One. 8: e78115. PMID 24205116 DOI: 10.1371/Journal.Pone.0078115 |
0.081 |
|
| 2003 |
Post DE, Khuri FR, Simons JW, Van Meir EG. Replicative oncolytic adenoviruses in multimodal cancer regimens. Human Gene Therapy. 14: 933-46. PMID 12869212 DOI: 10.1089/104303403766682205 |
0.081 |
|
| 1996 |
Baltuch GH, de Tribolet N, Van Meir EG. Expression of the CD44 adhesion molecule in tumours of the central and peripheral nervous system. Journal of Neuro-Oncology. 26: 191-8. PMID 8750185 DOI: 10.1007/BF01052622 |
0.079 |
|
| 2016 |
Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon RE, ... ... Van Meir EG, et al. Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27269943 DOI: 10.1200/Jco.2015.65.7825 |
0.077 |
|
| 2017 |
Osuka S, Van Meir EG. Cancer therapy: Neutrophils traffic in cancer nanodrugs. Nature Nanotechnology. PMID 28650438 DOI: 10.1038/nnano.2017.82 |
0.07 |
|
| 2016 |
Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AA, ... ... Van Meir EG, et al. Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis. The Lancet. Oncology. PMID 26976201 DOI: 10.1016/S1470-2045(15)00581-1 |
0.065 |
|
| 2018 |
Kaluz S, Tan C, Van Meir EG. Taking a HIF pill for old age diseases? Aging. PMID 29500331 DOI: 10.18632/aging.101395 |
0.059 |
|
| 2022 |
Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, ... ... Van Meir EG, et al. Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. PMID 36446943 DOI: 10.1038/s41586-022-05578-0 |
0.058 |
|
| 2011 |
Kaluz S, Van Meir EG. At the crossroads of cancer and inflammation: Ras rewires an HIF-driven IL-1 autocrine loop. Journal of Molecular Medicine (Berlin, Germany). 89: 91-4. PMID 21161499 DOI: 10.1007/s00109-010-0706-2 |
0.052 |
|
| 2016 |
Tyler K, Lee S, Van Meir E. Preparation of Recombinant Galectin-3 for Cancer Studies Bio-Protocol. 6. DOI: 10.21769/BIOPROTOC.1696 |
0.052 |
|
| 2011 |
Moriera F, So K, Gould P, Kamnasaran D, Jensen RL, Hussain I, Gutmann DH, Gorovets D, Kastenhuber ER, Pentsova E, Nayak L, Huse JT, van den Bent MJ, Gravendeel LA, Gorlia T, ... ... Van Meir EG, et al. -OMICS AND PROGNOSTIC MARKERS Neuro-Oncology. 13: iii76-iii84. DOI: 10.1093/Neuonc/Nor167 |
0.05 |
|
| 2020 |
Li C, Van Meir EG. The advent of precision epigenetics for medulloblastoma. Oncoscience. 7: 47-48. PMID 32923515 DOI: 10.18632/oncoscience.507 |
0.045 |
|
| 1997 |
van Meir EG. Identification of nude mice in tumorigenicity assays. International Journal of Cancer. 71: 310. PMID 9139859 DOI: 10.1002/(SICI)1097-0215(19970410)71:2<310::AID-IJC29>3.0.CO;2-J |
0.042 |
|
| 2012 |
Xu S, Kaluz S, Van Meir E, Marcus A. 5-D confocal imaging to visualize glioblastoma spheroid invasion into the extracellular matrix Microscopy and Microanalysis. 18: 180-181. DOI: 10.1017/S1431927612002759 |
0.038 |
|
| 2004 |
Van Meir EG. Opening the chamber of peer-review secrets. Nature. 429: 803. PMID 15215836 DOI: 10.1038/429803c |
0.034 |
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