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Thomas R.R. Pettus, Ph.D. - Publications

Affiliations: 
Chemistry and Biochemistry University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
synthetic organic chemistry, o-quinone methides, cyclohexadienones,
Website:
http://www.chem.ucsb.edu/people/tom-r-pettus
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63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pettus TR. Nucleophilic Addition of 4,5-Dihydrooxazole Derivatives to Base Generated o-Quinone Methides: A Four-Component Reaction The Journal of Organic Chemistry. 88: 2583-2588. DOI: 10.1021/acs.joc.2c02614  0.461
2019 Pettus TR. Nucleophilic Imines and Electrophilic o-Quinone Methides, a Three-Component Assembly of Assorted 3,4-Dihydro-2H-1,3-benzoxazines Organic Letters. DOI: 10.1021/acs.orglett.9b02655  0.376
2018 Pettus T, Feng Z, Burnett G. A Biomimetic Synthesis of des-Hydroxy Paecilospirone Synlett. 29: 1517-1519. DOI: 10.1055/s-0036-1592001  0.443
2018 Pettus T, Feng Z, Burnett G. A Biomimetic Synthesis of des-Hydroxy Paecilospirone Synlett. 29: 1517-1519. DOI: 10.1055/s-0036-1592001  0.443
2018 Pettus T, Feng Z, Burnett G. A Biomimetic Synthesis of des-Hydroxy Paecilospirone Synlett. 29: 1517-1519. DOI: 10.1055/S-0036-1592001  0.801
2018 Pettus T, Feng Z, Burnett G. A Biomimetic Synthesis of des-Hydroxy Paecilospirone Synlett. 29: 1517-1519. DOI: 10.1055/S-0036-1592001  0.801
2015 Feng ZG, Bai WJ, Pettus TR. Unified total syntheses of (-)-medicarpin, (-)-sophoracarpan A, and (±)-kushecarpin A with some structural revisions. Angewandte Chemie (International Ed. in English). 54: 1864-7. PMID 25476784 DOI: 10.1002/Anie.201408910  0.767
2014 Bai WJ, David JG, Feng ZG, Weaver MG, Wu KL, Pettus TR. The domestication of ortho-quinone methides. Accounts of Chemical Research. 47: 3655-64. PMID 25469551 DOI: 10.1021/Ar500330X  0.829
2014 David JG, Bai WJ, Weaver MG, Pettus TR. A general diastereoselective catalytic vinylogous aldol reaction among tetramic acid-derived pyrroles. Organic Letters. 16: 4384-7. PMID 25119431 DOI: 10.1021/Ol501715R  0.764
2014 Weaver MG, Bai WJ, Jackson SK, Pettus TR. Diels-Alder construction of regiodifferentiated meta-amino phenols and derivatives. Organic Letters. 16: 1294-7. PMID 24524325 DOI: 10.1021/Ol4034447  0.78
2012 Green JC, Burnett GL, Pettus TR. New strategies for natural products containing chroman spiroketals. Pure and Applied Chemistry. Chimie Pure Et Appliquee. 84: 1621-1631. PMID 25554712 DOI: 10.1351/Pac-Con-11-10-34  0.723
2012 Bai WJ, Jackson SK, Pettus TR. Mild construction of 3-methyl tetramic acids enabling a formal synthesis of palau'imide. Organic Letters. 14: 3862-5. PMID 22804621 DOI: 10.1021/Ol301556A  0.725
2012 Green JC, Brown ER, Pettus TR. Intramolecular condensation via an o-quinone methide: total synthesis of (±)-heliol. Organic Letters. 14: 2929-31. PMID 22650973 DOI: 10.1021/Ol301092W  0.751
2012 Cohn EP, Wu KL, Pettus TR, Reich NO. A new strategy for detection and development of tractable telomerase inhibitors. Journal of Medicinal Chemistry. 55: 3678-86. PMID 22413845 DOI: 10.1021/Jm201191D  0.655
2012 Bai WJ, Green JC, Pettus TR. Total syntheses of ent-heliespirones A and C. The Journal of Organic Chemistry. 77: 379-87. PMID 22074003 DOI: 10.1021/Jo201971G  0.721
2011 Green JC, Jiménez-Alonso S, Brown ER, Pettus TR. Total synthesis and repudiation of the helianane family. Organic Letters. 13: 5500-3. PMID 21928811 DOI: 10.1021/Ol2022214  0.799
2011 Wu KL, Mercado EV, Pettus TR. A convergent total synthesis of (±)-γ-rubromycin. Journal of the American Chemical Society. 133: 6114-7. PMID 21452818 DOI: 10.1021/Ja1115524  0.635
2011 Cha JY, Burnett GL, Huang Y, Davidson JB, Pettus TR. A strategy for the late-stage divergent syntheses of scyphostatin analogues. The Journal of Organic Chemistry. 76: 1361-71. PMID 21250721 DOI: 10.1021/Jo102327E  0.751
2011 Green JC, Pettus TR. An oxidative dearomatization-induced [5 + 2] cascade enabling the syntheses of α-cedrene, α-pipitzol, and sec-cedrenol. Journal of the American Chemical Society. 133: 1603-8. PMID 21194216 DOI: 10.1021/Ja109925G  0.671
2011 Wenderski TA, Marsini MA, Pettus TR. A diastereoselective formal synthesis of berkelic acid. Organic Letters. 13: 118-21. PMID 21138313 DOI: 10.1021/Ol102652T  0.842
2010 Wenderski TA, Hoarau C, Mejorado L, Pettus TR. Dearomatization applications of I((III)) reagents and some unusual reactivity amongst resorcinol derived cyclohexadienones. Tetrahedron. 66: 5873-5883. PMID 23750053 DOI: 10.1016/J.Tet.2010.05.041  0.803
2009 Wenderski TA, Denatale V, Pettus TR. Synthesis of 2,2-Disubstituted Pentalenes and Indenes by a Useful Modification to Nakamura's DMCP [3+2]-Cycloaddition Protocol. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 16: 2637-2642. PMID 21442051 DOI: 10.1055/S-0029-1217755  0.817
2009 Cha JY, Huang Y, Pettus TR. Total synthesis of TK-57-164A, isariotin F, and their putative progenitor isariotin E. Angewandte Chemie (International Ed. in English). 48: 9519-21. PMID 19921667 DOI: 10.1002/Anie.200904716  0.574
2009 Wenderski TA, Huang S, Pettus TR. Enantioselective total synthesis of all of the known chiral cleroindicins (C-F): clarification among optical rotations and assignments. The Journal of Organic Chemistry. 74: 4104-9. PMID 19476394 DOI: 10.1021/Jo900401K  0.798
2009 Miller LA, Marsini MA, Pettus TR. Chemoselective reactions of 3-benzyloxy-1,2-o-quinone with organometallic reagents. Organic Letters. 11: 1955-8. PMID 19331343 DOI: 10.1021/Ol9004068  0.814
2009 Pettus T, Pettus L. Intermolecular Applications of o-Quinone Methides (o-QMs) Anionically Generated at Low Temperatures: Kinetic Conditions Quinone Methides. 89-117. DOI: 10.1002/9780470452882.ch4  0.796
2008 Huang Y, Pettus TR. A Cycloaddition Strategy for Use toward Berkelic Acid, an MMP Inhibitor and Potent Anticancer Agent Displaying a Unique Chroman Spiroketal Motif. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 9: 1353-1356. PMID 19183702 DOI: 10.1055/S-2008-1072750  0.611
2008 Marsini MA, Huang Y, Lindsey CC, Wu KL, Pettus TR. Diastereoselective syntheses of chroman spiroketals via [4 + 2] cycloaddition of enol ethers and o-quinone methides. Organic Letters. 10: 1477-80. PMID 18336038 DOI: 10.1021/Ol8003244  0.817
2008 Pettus T, Wenderski T. Chapter 13 Seduced by a siren's call: expanding applications for aromatic compounds and the synthesis of (+)-rishirilide B Strategies and Tactics in Organic Synthesis. 7: 460-490. DOI: 10.1016/S1874-6004(08)80017-2  0.829
2007 Wu KL, Wilkinson S, Reich NO, Pettus TR. Facile synthesis of naphthoquinone spiroketals by diastereoselective oxidative [3 + 2] cycloaddition. Organic Letters. 9: 5537-40. PMID 18044909 DOI: 10.1021/Ol702450D  0.582
2007 Marsini MA, Huang Y, Van De Water RW, Pettus TR. Synthesis of resorcinol derived spironitronates. Organic Letters. 9: 3229-32. PMID 17645344 DOI: 10.1021/Ol0710257  0.808
2007 Pettus T, Mejorado L. Synthesis of (+)-Rishirilide B Synfacts. 2007: 0463-0463. DOI: 10.1055/s-2007-968399  0.371
2007 Pettus T, Mejorado L. Synthesis of (+)-Rishirilide B Synfacts. 2007: 0463-0463. DOI: 10.1055/S-2007-968399  0.791
2007 Pettus T, Mejorado L. Synthesis of (+)-Rishirilide B Synfacts. 2007: 0463-0463. DOI: 10.1055/s-2007-968399  0.371
2007 Pettus T, Mejorado L. Synthesis of (+)-Rishirilide B Synfacts. 2007: 0463-0463. DOI: 10.1055/s-2007-968399  0.371
2007 Pettus T, Mejorado L. Synthesis of (+)-Rishirilide B Synfacts. 2007: 0463-0463. DOI: 10.1055/S-2007-968399  0.791
2006 Selenski C, Pettus TR. (±)-Diinsininone: made nature's way. Tetrahedron. 62: 5298-5307. PMID 19079766 DOI: 10.1016/J.Tet.2006.01.109  0.819
2006 Mejorado L, Pettus TR. Diastereoselective Synthesis of a Simplified Core of Rishirilide B. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 3209-3214. PMID 18846264 DOI: 10.1055/S-2006-950188  0.835
2006 Lindsey CC, Pettus TR. Unusual cycloadditions of o-quinone methides with oxazoles. Tetrahedron Letters. 47: 201-204. PMID 18592015 DOI: 10.1016/J.Tetlet.2005.10.168  0.716
2006 Mejorado LH, Pettus TR. Total synthesis of (+)-rishirilide B: development and application of general processes for enantioselective oxidative dearomatization of resorcinol derivatives. Journal of the American Chemical Society. 128: 15625-31. PMID 17147370 DOI: 10.1021/Ja062987W  0.857
2006 Marsini MA, Gowin KM, Pettus TR. Total synthesis of (+/-)-mitorubrinic acid. Organic Letters. 8: 3481-3. PMID 16869640 DOI: 10.1021/Ol0610993  0.798
2006 Hoarau C, Pettus TR. General synthesis for chiral 4-alkyl-4-hydroxycyclohexenones. Organic Letters. 8: 2843-6. PMID 16774271 DOI: 10.1021/Ol061000S  0.693
2006 Lindsey CC, Wu KL, Pettus TR. Synthesis of electron deficient 5,6-aryloxy spiroketals. Organic Letters. 8: 2365-7. PMID 16706527 DOI: 10.1021/Ol0606886  0.741
2006 Pettus T, Huang Y, Zhang J. Synthesis of (±)-Brazilin Synfacts. 2006: 0424-0424. DOI: 10.1055/s-2006-934391  0.311
2006 Pettus T, Huang Y, Zhang J. Synthesis of (±)-Brazilin Synfacts. 2006: 0424-0424. DOI: 10.1055/s-2006-934391  0.311
2006 Pettus T, Huang Y, Zhang J. Synthesis of (±)-Brazilin Synfacts. 2006: 0424-0424. DOI: 10.1055/s-2006-934391  0.594
2006 Pettus T, Huang Y, Zhang J. Synthesis of (±)-Brazilin Synfacts. 2006: 0424-0424. DOI: 10.1055/s-2006-934391  0.311
2006 Pettus T, Huang Y, Zhang J. Synthesis of (±)-Brazilin Synfacts. 2006: 0424-0424. DOI: 10.1055/S-2006-934391  0.515
2005 Huang Y, Zhang J, Pettus TR. Synthesis of (+/-)-brazilin using IBX. Organic Letters. 7: 5841-4. PMID 16354080 DOI: 10.1021/Ol0523749  0.785
2004 McQuaid KM, Pettus TR. Chemoselective Epoxidation of Electron Deficient Enones with Iodosylbenzene. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 13: 2403-2405. PMID 19079634 DOI: 10.1055/S-2004-832814  0.675
2004 Selenski C, Pettus TR. Enantioselective [4 + 2] cycloadditions of o-quinone methides: total synthesis of (+)-mimosifoliol and formal synthesis of (+)-tolterodine. The Journal of Organic Chemistry. 69: 9196-203. PMID 15609955 DOI: 10.1021/Jo048703C  0.845
2004 Mejorado LH, Hoarau C, Pettus TR. Diastereoselective dearomatization of resorcinols directed by a lactic acid tether: unprecedented enantioselective access to p-quinols. Organic Letters. 6: 1535-8. PMID 15128229 DOI: 10.1021/Ol0498592  0.818
2004 Magdziak D, Meek SJ, Pettus TR. Cyclohexadienone ketals and quinols: four building blocks potentially useful for enantioselective synthesis. Chemical Reviews. 104: 1383-430. PMID 15008626 DOI: 10.1021/Cr0306900  0.791
2003 Hoarau C, Pettus TR. Strategies for the Preparation of Differentially Protected ortho-Prenylated Phenols. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 127-137. PMID 18563206 DOI: 10.1055/S-2003-36234  0.668
2002 Jones RM, Selenski C, Pettus TR. Rapid syntheses of benzopyrans from o-OBOC salicylaldehydes and salicyl alcohols: a three-component reaction. The Journal of Organic Chemistry. 67: 6911-5. PMID 12353982 DOI: 10.1021/Jo020224V  0.821
2002 Magdziak D, Rodriguez AA, Van De Water RW, Pettus TR. Regioselective oxidation of phenols to o-quinones with o-iodoxybenzoic acid (IBX). Organic Letters. 4: 285-8. PMID 11796071 DOI: 10.1021/Ol017068J  0.793
2001 Jones RM, Van De Water RW, Lindsey CC, Hoarau C, Ung T, Pettus TR. A mild anionic method for generating o-quinone methides: facile preparations of ortho-functionalized phenols. The Journal of Organic Chemistry. 66: 3435-41. PMID 11348127 DOI: 10.1021/Jo001752E  0.783
2001 Pettus LH, Van De Water RW, Pettus TR. Synthesis of (+/-)-epoxysorbicillinol using a novel cyclohexa-2,5-dienone with synthetic applications to other sorbicillin derivatives. Organic Letters. 3: 905-8. PMID 11263912 DOI: 10.1021/Ol0155438  0.836
2001 Magdziak D, Pettus LH, Pettus TR. Enantioselective hydride abstraction in organic substrates: a novel use for chiral carbenium ions. Organic Letters. 3: 557-9. PMID 11178824 DOI: 10.1021/Ol006963K  0.788
2000 Martello LA, McDaid HM, Regl DL, Yang CP, Meng D, Pettus TR, Kaufman MD, Arimoto H, Danishefsky SJ, Smith AB, Horwitz SB. Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 1978-87. PMID 10815923  0.401
1998 Chen X, Zhou B, Bhattacharya S, Gutteridge C, Pettus T, Danishefsky S. Totalsynthese von Eleutherobin: zum Schluß eine Überraschung Angewandte Chemie. 110: 835-838. DOI: 10.1002/(Sici)1521-3757(19980316)110:6<835::Aid-Ange835>3.0.Co;2-0  0.724
1998 Chen X, Gutteridge C, Bhattacharya S, Zhou B, Pettus T, Hascall T, Danishefsky S. Eine konvergente Route zur Totalsynthese der Eleutheside Angewandte Chemie. 110: 195-197. DOI: 10.1002/(Sici)1521-3757(19980116)110:1/2<195::Aid-Ange195>3.0.Co;2-C  0.75
1989 Hudlicky T, Seoane G, Pettus T. Enantioselective synthesis of (-)-zeylena from styrene Journal of Organic Chemistry. 54: 4239-4243. DOI: 10.1021/Jo00278A052  0.539
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