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James C. Liao - Publications

University of California, Los Angeles, Los Angeles, CA 
Chemical and Biomolecular Engineering

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ohtake T, Kawase N, Pontrelli S, Nitta K, Laviña WA, Shen CR, Putri SP, Liao JC, Fukusaki E. Metabolomics-Driven Identification of the Rate-Limiting Steps in 1-Propanol Production. Frontiers in Microbiology. 13: 871624. PMID 35495658 DOI: 10.3389/fmicb.2022.871624  0.323
2020 Chen FY, Jung HW, Tsuei CY, Liao JC. Converting Escherichia coli to a Synthetic Methylotroph Growing Solely on Methanol. Cell. PMID 32780992 DOI: 10.1016/J.Cell.2020.07.010  0.405
2019 Chen CT, Chen FY, Bogorad IW, Wu TY, Derks J, Zhang R, Lee AS, Jones ME, Liao JC. Corrigendum to "Synthetic methanol auxotrophy of Escherichia coli for methanol-dependent growth and production" [Metab. Eng. 49 (2018) 257-266]. Metabolic Engineering. 54: 292. PMID 31102942 DOI: 10.1016/J.Ymben.2019.04.006  0.353
2019 Nishiguchi H, Hiasa N, Uebayashi K, Liao J, Shimizu H, Matsuda F. Transomics data-driven, ensemble kinetic modeling for system-level understanding and engineering of the cyanobacteria central metabolism. Metabolic Engineering. PMID 30633975 DOI: 10.1016/J.Ymben.2019.01.004  0.425
2018 Putri SP, Nakayama Y, Shen C, Noguchi S, Nitta K, Bamba T, Pontrelli S, Liao J, Fukusaki E. Identifying metabolic elements that contribute to productivity of 1-propanol bioproduction using metabolomic analysis. Metabolomics : Official Journal of the Metabolomic Society. 14: 96. PMID 30830363 DOI: 10.1007/S11306-018-1386-0  0.436
2018 Nitta K, Laviña WA, Pontrelli S, Liao JC, Putri SP, Fukusaki E. Metabolome analysis revealed the knockout of glyoxylate shunt as an effective strategy for improvement of 1-butanol production in transgenic Escherichia coli. Journal of Bioscience and Bioengineering. PMID 30482596 DOI: 10.1016/J.Jbiosc.2018.08.013  0.435
2018 Pontrelli S, Fricke RCB, Teoh ST, Laviña WA, Putri SP, Fitz-Gibbon S, Chung M, Pellegrini M, Fukusaki E, Liao JC. Metabolic repair through emergence of new pathways in Escherichia coli. Nature Chemical Biology. 14: 1005-1009. PMID 30327558 DOI: 10.1038/S41589-018-0149-6  0.405
2018 Yu H, Liao JC. A modified serine cycle in Escherichia coli coverts methanol and CO to two-carbon compounds. Nature Communications. 9: 3992. PMID 30266898 DOI: 10.1038/S41467-018-06496-4  0.361
2018 Chen CT, Chen FY, Bogorad IW, Wu TY, Zhang R, Lee AS, Liao JC. Synthetic methanol auxotrophy of Escherichia coli for methanol-dependent growth and production. Metabolic Engineering. PMID 30172686 DOI: 10.1016/J.Ymben.2018.08.010  0.388
2018 Pontrelli S, Fricke RCB, Sakurai SSM, Putri SP, Fitz-Gibbon S, Chung M, Wu HY, Chen YJ, Pellegrini M, Fukusaki E, Liao JC. Directed strain evolution restructures metabolism for 1-butanol production in minimal media. Metabolic Engineering. PMID 30107263 DOI: 10.1016/J.Ymben.2018.08.004  0.448
2018 Fathima AM, Chuang D, Laviña WA, Liao J, Putri SP, Fukusaki E. Iterative cycle of widely targeted metabolic profiling for the improvement of 1-butanol titer and productivity in . Biotechnology For Biofuels. 11: 188. PMID 30002728 DOI: 10.1186/S13068-018-1187-8  0.411
2018 Yu H, Li X, Duchoud F, Chuang DS, Liao JC. Augmenting the Calvin-Benson-Bassham cycle by a synthetic malyl-CoA-glycerate carbon fixation pathway. Nature Communications. 9: 2008. PMID 29789614 DOI: 10.1038/S41467-018-04417-Z  0.358
2018 Pontrelli S, Chiu TY, Lan EI, Chen FY, Chang PC, Liao JC. Escherichia coli as a host for metabolic engineering. Metabolic Engineering. PMID 29689382 DOI: 10.1016/J.Ymben.2018.04.008  0.773
2018 Lin PP, Jaeger AJ, Wu TY, Xu SC, Lee AS, Gao F, Chen PW, Liao JC. Construction and evolution of anstrain relying on nonoxidative glycolysis for sugar catabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 29555759 DOI: 10.1073/Pnas.1802191115  0.417
2018 Black W, Zhang L, Kamoku C, Liao JC, Li H. Rearrangement of Coenzyme A-acylated carbon chain enables synthesis of isobutanol via a novel pathway in Ralstonia eutropha. Acs Synthetic Biology. PMID 29429336 DOI: 10.1021/Acssynbio.7B00409  0.51
2017 Nitta K, Laviña WA, Pontrelli S, Liao JC, Putri SP, Fukusaki E. Orthogonal partial least squares/projections to latent structures regression-based metabolomics approach for identification of gene targets for improvement of 1-butanol production in Escherichia coli. Journal of Bioscience and Bioengineering. PMID 28669528 DOI: 10.1016/J.Jbiosc.2017.05.015  0.409
2017 Ohtake T, Pontrelli S, Laviña WA, Liao JC, Putri SP, Fukusaki E. Metabolomics-driven approach to solving a CoA imbalance for improved 1-butanol production in Escherichia coli. Metabolic Engineering. PMID 28400330 DOI: 10.1016/J.Ymben.2017.04.003  0.484
2017 Lafontaine Rivera JG, Theisen MK, Chen PW, Liao JC. Kinetically accessible yield (KAY) for redirection of metabolism to produce exo-metabolites. Metabolic Engineering. PMID 28389394 DOI: 10.1016/J.Ymben.2017.03.011  0.412
2017 Chen PW, Theisen MK, Liao JC. Metabolic systems modeling for cell factories improvement. Current Opinion in Biotechnology. 46: 114-119. PMID 28388485 DOI: 10.1016/J.Copbio.2017.02.005  0.338
2017 Wang J, Jain R, Shen X, Sun X, Cheng M, Liao JC, Yuan Q, Yan Y. Rational engineering of diol dehydratase enables 1,4-butanediol biosynthesis from xylose. Metabolic Engineering. PMID 28215518 DOI: 10.1016/J.Ymben.2017.02.003  0.4
2017 Soh LM, Mak WS, Lin PP, Mi L, Chen FY, Damoiseaux R, Siegel JB, Liao JC. Engineering a thermostable keto acid decarboxylase using directed evolution and computationally directed protein design. Acs Synthetic Biology. PMID 28052191 DOI: 10.1021/Acssynbio.6B00240  0.339
2016 Xiong W, Lin PP, Magnusson L, Warner L, Liao JC, Maness PC, Chou KJ. CO2-fixing one-carbon metabolism in a cellulose-degrading bacterium Clostridium thermocellum. Proceedings of the National Academy of Sciences of the United States of America. PMID 27794122 DOI: 10.1073/Pnas.1605482113  0.592
2016 Liao JC, Mi L, Pontrelli S, Luo S. Fuelling the future: microbial engineering for the production of sustainable biofuels. Nature Reviews. Microbiology. PMID 27026253 DOI: 10.1038/Nrmicro.2016.32  0.384
2016 Theisen MK, Lafontaine Rivera JG, Liao JC. Stability of Ensemble Models Predicts Productivity of Enzymatic Systems. Plos Computational Biology. 12: e1004800. PMID 26963521 DOI: 10.1371/Journal.Pcbi.1004800  0.345
2016 Wu TY, Chen CT, Liu JT, Bogorad IW, Damoiseaux R, Liao JC. Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1. Applied Microbiology and Biotechnology. PMID 26846745 DOI: 10.1007/S00253-016-7320-3  0.321
2016 Chen CT, Liao JC. Frontiers in microbial 1-butanol and isobutanol production. Fems Microbiology Letters. PMID 26832641 DOI: 10.1093/Femsle/Fnw020  0.408
2016 Wernick DG, Pontrelli SP, Pollock AW, Liao JC. Sustainable biorefining in wastewater by engineered extreme alkaliphile Bacillus marmarensis. Scientific Reports. 6: 20224. PMID 26831574 DOI: 10.1038/Srep20224  0.319
2016 Noguchi S, Putri SP, Lan EI, Laviña WA, Dempo Y, Bamba T, Liao JC, Fukusaki E. Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production. Metabolomics : Official Journal of the Metabolomic Society. 12: 26. PMID 26766939 DOI: 10.1007/S11306-015-0940-2  0.78
2015 Mak WS, Tran S, Marcheschi R, Bertolani S, Thompson J, Baker D, Liao JC, Siegel JB. Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway. Nature Communications. 6: 10005. PMID 26598135 DOI: 10.1038/Ncomms10005  0.353
2015 Lan EI, Chuang DS, Shen CR, Lee AM, Ro SY, Liao JC. Metabolic engineering of cyanobacteria for photosynthetic 3-hydroxypropionic acid production from CO2 using Synechococcus elongatus PCC 7942. Metabolic Engineering. PMID 26278506 DOI: 10.1016/J.Ymben.2015.08.002  0.779
2015 Lin PP, Mi L, Morioka AH, Yoshino KM, Konishi S, Xu SC, Papanek BA, Riley LA, Guss AM, Liao JC. Consolidated bioprocessing of cellulose to isobutanol using Clostridium thermocellum. Metabolic Engineering. 31: 44-52. PMID 26170002 DOI: 10.1016/J.Ymben.2015.07.001  0.435
2015 Lafontaine Rivera JG, Lee Y, Liao JC. An entropy-like index of bifurcational robustness for metabolic systems. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 25855352 DOI: 10.1039/C4Ib00257A  0.375
2015 Ho CK, Rahib L, Liao JC, Sriram G, Dipple KM. Mathematical modeling of the insulin signal transduction pathway for prediction of insulin sensitivity from expression data. Molecular Genetics and Metabolism. 114: 66-72. PMID 25468647 DOI: 10.1016/J.Ymgme.2014.11.003  0.3
2015 Li H, Liao JC. A synthetic anhydrotetracycline-controllable gene expression system in Ralstonia eutropha H16. Acs Synthetic Biology. 4: 101-6. PMID 24702232 DOI: 10.1021/Sb4001189  0.486
2014 Bogorad IW, Chen CT, Theisen MK, Wu TY, Schlenz AR, Lam AT, Liao JC. Building carbon-carbon bonds using a biocatalytic methanol condensation cycle. Proceedings of the National Academy of Sciences of the United States of America. 111: 15928-33. PMID 25355907 DOI: 10.1073/Pnas.1413470111  0.319
2014 Lee Y, Lafontaine Rivera JG, Liao JC. Ensemble Modeling for Robustness Analysis in engineering non-native metabolic pathways. Metabolic Engineering. 25: 63-71. PMID 24972370 DOI: 10.1016/J.Ymben.2014.06.006  0.388
2014 Khodayari A, Zomorrodi AR, Liao JC, Maranas CD. A kinetic model of Escherichia coli core metabolism satisfying multiple sets of mutant flux data. Metabolic Engineering. 25: 50-62. PMID 24928774 DOI: 10.1016/J.Ymben.2014.05.014  0.374
2014 Nielsen J, Fussenegger M, Keasling J, Lee SY, Liao JC, Prather K, Palsson B. Engineering synergy in biotechnology. Nature Chemical Biology. 10: 319-22. PMID 24743245 DOI: 10.1038/Nchembio.1519  0.505
2014 Lin PP, Rabe KS, Takasumi JL, Kadisch M, Arnold FH, Liao JC. Isobutanol production at elevated temperatures in thermophilic Geobacillus thermoglucosidasius. Metabolic Engineering. 24: 1-8. PMID 24721011 DOI: 10.1016/J.Ymben.2014.03.006  0.382
2014 Li X, Shen CR, Liao JC. Isobutanol production as an alternative metabolic sink to rescue the growth deficiency of the glycogen mutant of Synechococcus elongatus PCC 7942. Photosynthesis Research. 120: 301-10. PMID 24590366 DOI: 10.1007/S11120-014-9987-6  0.387
2014 Harper M, Gronenberg L, Liao J, Lee C. Comprehensive detection of genes causing a phenotype using phenotype sequencing and pathway analysis. Plos One. 9: e88072. PMID 24586303 DOI: 10.1371/Journal.Pone.0088072  0.379
2014 Choi KY, Wernick DG, Tat CA, Liao JC. Consolidated conversion of protein waste into biofuels and ammonia using Bacillus subtilis. Metabolic Engineering. 23: 53-61. PMID 24566040 DOI: 10.1016/J.Ymben.2014.02.007  0.403
2014 Li H, Liao JC. Development of an NADPH-dependent homophenylalanine dehydrogenase by protein engineering. Acs Synthetic Biology. 3: 13-20. PMID 24053171 DOI: 10.1021/Sb400093X  0.53
2013 Bogorad IW, Lin TS, Liao JC. Synthetic non-oxidative glycolysis enables complete carbon conservation. Nature. 502: 693-7. PMID 24077099 DOI: 10.1038/Nature12575  0.342
2013 Kusakabe T, Tatsuke T, Tsuruno K, Hirokawa Y, Atsumi S, Liao JC, Hanai T. Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light. Metabolic Engineering. 20: 101-8. PMID 24076145 DOI: 10.1016/J.Ymben.2013.09.007  0.628
2013 Minty JJ, Singer ME, Scholz SA, Bae CH, Ahn JH, Foster CE, Liao JC, Lin XN. Design and characterization of synthetic fungal-bacterial consortia for direct production of isobutanol from cellulosic biomass. Proceedings of the National Academy of Sciences of the United States of America. 110: 14592-7. PMID 23959872 DOI: 10.1073/Pnas.1218447110  0.441
2013 Mainguet SE, Gronenberg LS, Wong SS, Liao JC. A reverse glyoxylate shunt to build a non-native route from C4 to C2 in Escherichia coli. Metabolic Engineering. 19: 116-27. PMID 23938029 DOI: 10.1016/J.Ymben.2013.06.004  0.391
2013 Gronenberg LS, Marcheschi RJ, Liao JC. Next generation biofuel engineering in prokaryotes. Current Opinion in Chemical Biology. 17: 462-71. PMID 23623045 DOI: 10.1016/J.Cbpa.2013.03.037  0.381
2013 Marcheschi RJ, Gronenberg LS, Liao JC. Protein engineering for metabolic engineering: current and next-generation tools. Biotechnology Journal. 8: 545-55. PMID 23589443 DOI: 10.1002/Biot.201200371  0.38
2013 Zomorrodi AR, Lafontaine Rivera JG, Liao JC, Maranas CD. Optimization-driven identification of genetic perturbations accelerates the convergence of model parameters in ensemble modeling of metabolic networks. Biotechnology Journal. 8: 1090-104. PMID 23450699 DOI: 10.1002/Biot.201200270  0.358
2013 Shen CR, Liao JC. Synergy as design principle for metabolic engineering of 1-propanol production in Escherichia coli. Metabolic Engineering. 17: 12-22. PMID 23376654 DOI: 10.1016/J.Ymben.2013.01.008  0.429
2013 Li H, Liao JC. Engineering a cyanobacterium as the catalyst for the photosynthetic conversion of CO2 to 1,2-propanediol. Microbial Cell Factories. 12: 4. PMID 23339487 DOI: 10.1186/1475-2859-12-4  0.53
2013 Wernick DG, Liao JC. Protein-based biorefining: metabolic engineering for production of chemicals and fuel with regeneration of nitrogen fertilizers. Applied Microbiology and Biotechnology. 97: 1397-406. PMID 23296497 DOI: 10.1007/S00253-012-4605-Z  0.396
2013 Lan EI, Liao JC. Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources. Bioresource Technology. 135: 339-49. PMID 23186690 DOI: 10.1016/J.Biortech.2012.09.104  0.751
2013 Li H, Liao JC. Biological conversion of carbon dioxide to photosynthetic fuels and electrofuels Energy and Environmental Science. 6: 2892-2899. DOI: 10.1039/C3Ee41847B  0.453
2013 Lan EI, Ro SY, Liao JC. Oxygen-tolerant coenzyme A-acylating aldehyde dehydrogenase facilitates efficient photosynthetic n-butanol biosynthesis in cyanobacteria Energy and Environmental Science. 6: 2672-2681. DOI: 10.1039/C3Ee41405A  0.773
2013 Lan EI, Dekishima Y, Chuang DS, Liao JC. Metabolic engineering of 2-pentanone synthesis in Escherichia coli Aiche Journal. 59: 3167-3175. DOI: 10.1002/Aic.14086  0.797
2012 Machado HB, Dekishima Y, Luo H, Lan EI, Liao JC. A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols. Metabolic Engineering. 14: 504-11. PMID 22819734 DOI: 10.1016/J.Ymben.2012.07.002  0.77
2012 Felnagle EA, Chaubey A, Noey EL, Houk KN, Liao JC. Engineering synthetic recursive pathways to generate non-natural small molecules. Nature Chemical Biology. 8: 518-26. PMID 22596203 DOI: 10.1038/Nchembio.959  0.396
2012 Lan EI, Liao JC. ATP drives direct photosynthetic production of 1-butanol in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 6018-23. PMID 22474341 DOI: 10.1073/Pnas.1200074109  0.785
2012 Li H, Opgenorth PH, Wernick DG, Rogers S, Wu TY, Higashide W, Malati P, Huo YX, Cho KM, Liao JC. Integrated electromicrobial conversion of CO2 to higher alcohols. Science (New York, N.Y.). 335: 1596. PMID 22461604 DOI: 10.1126/Science.1217643  0.446
2012 Tran LM, Chang CJ, Plaisier S, Wu S, Dang J, Mischel PS, Liao JC, Graeber TG, Wu H. Determining PTEN functional status by network component deduced transcription factor activities. Plos One. 7: e31053. PMID 22347425 DOI: 10.1371/Journal.Pone.0031053  0.557
2012 Marcheschi RJ, Li H, Zhang K, Noey EL, Kim S, Chaubey A, Houk KN, Liao JC. A synthetic recursive "+1" pathway for carbon chain elongation. Acs Chemical Biology. 7: 689-97. PMID 22242720 DOI: 10.1021/Cb200313E  0.534
2012 Li Y, Tschaplinski TJ, Engle NL, Hamilton CY, Rodriguez M, Liao JC, Schadt CW, Guss AM, Yang Y, Graham DE. Combined inactivation of the Clostridium cellulolyticum lactate and malate dehydrogenase genes substantially increases ethanol yield from cellulose and switchgrass fermentations. Biotechnology For Biofuels. 5: 2. PMID 22214220 DOI: 10.1186/1754-6834-5-2  0.376
2012 Huo YX, Wernick DG, Liao JC. Toward nitrogen neutral biofuel production. Current Opinion in Biotechnology. 23: 406-13. PMID 22054644 DOI: 10.1016/J.Copbio.2011.10.005  0.322
2012 Tan Y, Liao JC. Metabolic ensemble modeling for strain engineers. Biotechnology Journal. 7: 343-53. PMID 22021171 DOI: 10.1002/Biot.201100186  0.641
2012 Lu JL, Liao JC. Metabolic engineering and control analysis for production of aromatics: Role of transaldolase. Biotechnology and Bioengineering. 53: 132-8. PMID 18633957 DOI: 10.1002/(Sici)1097-0290(19970120)53:2<132::Aid-Bit2>3.0.Co;2-P  0.455
2012 Liao JC, Hou SY, Chao YP. Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnology and Bioengineering. 52: 129-40. PMID 18629859 DOI: 10.1002/(Sici)1097-0290(19961005)52:1<129::Aid-Bit13>3.0.Co;2-J  0.442
2012 Patnaik R, Spitzer RG, Liao JC. Pathway engineering for production of aromatics in Escherichia coli: Confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities. Biotechnology and Bioengineering. 46: 361-70. PMID 18623323 DOI: 10.1002/Bit.260460409  0.43
2012 Shen CR, Liao JC. Photosynthetic production of 2-methyl-1-butanol from CO 2 in cyanobacterium Synechococcus elongatus PCC7942 and characterization of the native acetohydroxyacid synthase Energy and Environmental Science. 5: 9574-9583. DOI: 10.1039/C2Ee23148D  0.43
2012 Lan EI, Liao JC. Corrigendum to "Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide" [Metab. Eng. 13 (2011) 353-363] Metabolic Engineering. 14: 68. DOI: 10.1016/J.Ymben.2011.11.001  0.765
2011 Hu CW, Chang YL, Chen SJ, Kuo-Huang LL, Liao JC, Huang HC, Juan HF. Revealing the functions of the transketolase enzyme isoforms in Rhodopseudomonas palustris using a systems biology approach. Plos One. 6: e28329. PMID 22174789 DOI: 10.1371/Journal.Pone.0028329  0.389
2011 Smith KM, Liao JC. An evolutionary strategy for isobutanol production strain development in Escherichia coli. Metabolic Engineering. 13: 674-81. PMID 21911074 DOI: 10.1016/J.Ymben.2011.08.004  0.558
2011 Dekishima Y, Lan EI, Shen CR, Cho KM, Liao JC. Extending carbon chain length of 1-butanol pathway for 1-hexanol synthesis from glucose by engineered Escherichia coli. Journal of the American Chemical Society. 133: 11399-401. PMID 21707101 DOI: 10.1021/Ja203814D  0.778
2011 Contador CA, Andrews BA, Liao JC, Asenjo JA. Identification of transcription factors perturbed by the synthesis of high levels of a foreign protein in yeast Saccharomyces cerevisiae. Biotechnology Progress. 27: 925-36. PMID 21656919 DOI: 10.1002/Btpr.616  0.39
2011 Shen CR, Liao JC. A synthetic iterative pathway for ketoacid elongation. Methods in Enzymology. 497: 469-81. PMID 21601099 DOI: 10.1016/B978-0-12-385075-1.00020-2  0.35
2011 Lan EI, Liao JC. Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide. Metabolic Engineering. 13: 353-63. PMID 21569861 DOI: 10.1016/J.Ymben.2011.04.004  0.795
2011 Baez A, Cho KM, Liao JC. High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal. Applied Microbiology and Biotechnology. 90: 1681-90. PMID 21547458 DOI: 10.1007/S00253-011-3173-Y  0.394
2011 Shen CR, Lan EI, Dekishima Y, Baez A, Cho KM, Liao JC. Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli. Applied and Environmental Microbiology. 77: 2905-15. PMID 21398484 DOI: 10.1128/Aem.03034-10  0.774
2011 Huo YX, Cho KM, Rivera JG, Monte E, Shen CR, Yan Y, Liao JC. Conversion of proteins into biofuels by engineering nitrogen flux. Nature Biotechnology. 29: 346-51. PMID 21378968 DOI: 10.1038/Nbt.1789  0.368
2011 Higashide W, Li Y, Yang Y, Liao JC. Metabolic engineering of Clostridium cellulolyticum for production of isobutanol from cellulose. Applied and Environmental Microbiology. 77: 2727-33. PMID 21378054 DOI: 10.1128/Aem.02454-10  0.446
2011 Tan Y, Rivera JG, Contador CA, Asenjo JA, Liao JC. Reducing the allowable kinetic space by constructing ensemble of dynamic models with the same steady-state flux. Metabolic Engineering. 13: 60-75. PMID 21075211 DOI: 10.1016/J.Ymben.2010.11.001  0.624
2011 Rizk ML, Laguna R, Smith KM, Tabita FR, Liao JC. Redox homeostasis phenotypes in RubisCO-deficient Rhodobacter sphaeroides via ensemble modeling. Biotechnology Progress. 27: 15-22. PMID 20939096 DOI: 10.1002/Btpr.506  0.752
2010 Li H, Cann AF, Liao JC. Biofuels: biomolecular engineering fundamentals and advances. Annual Review of Chemical and Biomolecular Engineering. 1: 19-36. PMID 22432571 DOI: 10.1146/Annurev-Chembioeng-073009-100938  0.802
2010 Atsumi S, Wu TY, Machado IM, Huang WC, Chen PY, Pellegrini M, Liao JC. Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli. Molecular Systems Biology. 6: 449. PMID 21179021 DOI: 10.1038/Msb.2010.98  0.595
2010 Mainguet SE, Liao JC. Bioengineering of microorganisms for C₃ to C₅ alcohols production. Biotechnology Journal. 5: 1297-308. PMID 21154669 DOI: 10.1002/Biot.201000276  0.347
2010 Tran LM, Hyduke DR, Liao JC. Trimming of mammalian transcriptional networks using network component analysis. Bmc Bioinformatics. 11: 511. PMID 20942926 DOI: 10.1186/1471-2105-11-511  0.754
2010 Inokuma K, Liao JC, Okamoto M, Hanai T. Improvement of isopropanol production by metabolically engineered Escherichia coli using gas stripping. Journal of Bioscience and Bioengineering. 110: 696-701. PMID 20696614 DOI: 10.1016/J.Jbiosc.2010.07.010  0.4
2010 Wong I, Atsumi S, Huang WC, Wu TY, Hanai T, Lam ML, Tang P, Yang J, Liao JC, Ho CM. An agar gel membrane-PDMS hybrid microfluidic device for long term single cell dynamic study. Lab On a Chip. 10: 2710-9. PMID 20664845 DOI: 10.1039/C004719H  0.547
2010 Dean JT, Rizk ML, Tan Y, Dipple KM, Liao JC. Ensemble modeling of hepatic fatty acid metabolism with a synthetic glyoxylate shunt. Biophysical Journal. 98: 1385-95. PMID 20409457 DOI: 10.1016/J.Bpj.2009.12.4308  0.792
2010 Sriram G, Parr LS, Rahib L, Liao JC, Dipple KM. Moonlighting function of glycerol kinase causes systems-level changes in rat hepatoma cells. Metabolic Engineering. 12: 332-40. PMID 20399282 DOI: 10.1016/J.Ymben.2010.04.001  0.364
2010 Smith KM, Cho KM, Liao JC. Engineering Corynebacterium glutamicum for isobutanol production. Applied Microbiology and Biotechnology. 87: 1045-55. PMID 20376637 DOI: 10.1007/S00253-010-2522-6  0.581
2010 Zhang K, Li H, Cho KM, Liao JC. Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine. Proceedings of the National Academy of Sciences of the United States of America. 107: 6234-9. PMID 20332210 DOI: 10.1073/Pnas.0912903107  0.471
2010 Connor MR, Cann AF, Liao JC. 3-Methyl-1-butanol production in Escherichia coli: random mutagenesis and two-phase fermentation. Applied Microbiology and Biotechnology. 86: 1155-64. PMID 20072783 DOI: 10.1007/S00253-009-2401-1  0.785
2010 Cann AF, Liao JC. Pentanol isomer synthesis in engineered microorganisms. Applied Microbiology and Biotechnology. 85: 893-9. PMID 19859707 DOI: 10.1007/S00253-009-2262-7  0.807
2010 Atsumi S, Wu TY, Eckl EM, Hawkins SD, Buelter T, Liao JC. Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes. Applied Microbiology and Biotechnology. 85: 651-7. PMID 19609521 DOI: 10.1007/S00253-009-2085-6  0.643
2010 Jarboe LR, Hyduke DR, Liao JC. Systems Approaches to Unraveling Nitric Oxide Response Networks in Prokaryotes Nitric Oxide. 103-136. DOI: 10.1016/B978-0-12-373866-0.00004-6  0.745
2010 Shen CR, Liao JC, Atsumi S. Metabolic engineering of Escherichia coli for 1-butanol and 1-propanol production via the keto-acid pathways Acs National Meeting Book of Abstracts 0.602
2009 Atsumi S, Higashide W, Liao JC. Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde. Nature Biotechnology. 27: 1177-80. PMID 19915552 DOI: 10.1038/Nbt.1586  0.613
2009 Yan Y, Lee CC, Liao JC. Enantioselective synthesis of pure (R,R)-2,3-butanediol in Escherichia coli with stereospecific secondary alcohol dehydrogenases. Organic & Biomolecular Chemistry. 7: 3914-7. PMID 19763290 DOI: 10.1039/B913501D  0.306
2009 Rizk ML, Liao JC. Ensemble modeling for aromatic production in Escherichia coli. Plos One. 4: e6903. PMID 19730732 DOI: 10.1371/Journal.Pone.0006903  0.719
2009 Atsumi S, Li Z, Liao JC. Acetolactate synthase from Bacillus subtilis serves as a 2-ketoisovalerate decarboxylase for isobutanol biosynthesis in Escherichia coli. Applied and Environmental Microbiology. 75: 6306-11. PMID 19684168 DOI: 10.1128/Aem.01160-09  0.612
2009 Lai D, Lluncor B, Schröder I, Gunsalus RP, Liao JC, Monbouquette HG. Reconstruction of the archaeal isoprenoid ether lipid biosynthesis pathway in Escherichia coli through digeranylgeranylglyceryl phosphate. Metabolic Engineering. 11: 184-91. PMID 19558961 DOI: 10.1016/J.Ymben.2009.01.008  0.375
2009 Brynildsen MP, Liao JC. An integrated network approach identifies the isobutanol response network of Escherichia coli. Molecular Systems Biology. 5: 277. PMID 19536200 DOI: 10.1038/Msb.2009.34  0.686
2009 Dean JT, Tran L, Beaven S, Tontonoz P, Reue K, Dipple KM, Liao JC. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metabolism. 9: 525-36. PMID 19490907 DOI: 10.1016/J.Cmet.2009.04.008  0.757
2009 Connor MR, Liao JC. Microbial production of advanced transportation fuels in non-natural hosts. Current Opinion in Biotechnology. 20: 307-15. PMID 19473829 DOI: 10.1016/J.Copbio.2009.04.002  0.698
2009 Contador CA, Rizk ML, Asenjo JA, Liao JC. Ensemble modeling for strain development of L-lysine-producing Escherichia coli. Metabolic Engineering. 11: 221-33. PMID 19379820 DOI: 10.1016/J.Ymben.2009.04.002  0.728
2009 Ye C, Galbraith SJ, Liao JC, Eskin E. Using network component analysis to dissect regulatory networks mediated by transcription factors in yeast. Plos Computational Biology. 5: e1000311. PMID 19300475 DOI: 10.1371/Journal.Pcbi.1000311  0.319
2009 Yan Y, Liao JC. Engineering metabolic systems for production of advanced fuels. Journal of Industrial Microbiology & Biotechnology. 36: 471-9. PMID 19198907 DOI: 10.1007/S10295-009-0532-0  0.431
2009 Rahib L, Sriram G, Harada MK, Liao JC, Dipple KM. Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency. Molecular Genetics and Metabolism. 96: 106-12. PMID 19121967 DOI: 10.1016/J.Ymgme.2008.11.163  0.308
2009 Wong WW, Tran LM, Liao JC. A hidden square-root boundary between growth rate and biomass yield. Biotechnology and Bioengineering. 102: 73-80. PMID 18683253 DOI: 10.1002/Bit.22046  0.565
2009 Delgado J, Meruane J, Liao JC. Experimental determination of flux control distribution in biochemical systems: in vitro model to analyze transient metabolite concentrations. Biotechnology and Bioengineering. 41: 1121-8. PMID 18601299 DOI: 10.1002/Bit.260411116  0.303
2009 Rizk ML, Liao JC. Ensemble modeling and related mathematical modeling of metabolic networks Journal of the Taiwan Institute of Chemical Engineers. 40: 595-601. DOI: 10.1016/J.Jtice.2009.05.003  0.714
2008 Zhang K, Sawaya MR, Eisenberg DS, Liao JC. Expanding metabolism for biosynthesis of nonnatural alcohols. Proceedings of the National Academy of Sciences of the United States of America. 105: 20653-8. PMID 19064911 DOI: 10.1073/Pnas.0807157106  0.405
2008 Atsumi S, Liao JC. Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli. Applied and Environmental Microbiology. 74: 7802-8. PMID 18952866 DOI: 10.1128/Aem.02046-08  0.648
2008 Tran LM, Rizk ML, Liao JC. Ensemble modeling of metabolic networks. Biophysical Journal. 95: 5606-17. PMID 18820235 DOI: 10.1529/Biophysj.108.135442  0.764
2008 Shen CR, Liao JC. Metabolic engineering of Escherichia coli for 1-butanol and 1-propanol production via the keto-acid pathways. Metabolic Engineering. 10: 312-20. PMID 18775501 DOI: 10.1016/J.Ymben.2008.08.001  0.409
2008 Atsumi S, Liao JC. Metabolic engineering for advanced biofuels production from Escherichia coli. Current Opinion in Biotechnology. 19: 414-9. PMID 18761088 DOI: 10.1016/J.Copbio.2008.08.008  0.618
2008 Cann AF, Liao JC. Production of 2-methyl-1-butanol in engineered Escherichia coli. Applied Microbiology and Biotechnology. 81: 89-98. PMID 18758769 DOI: 10.1007/S00253-008-1631-Y  0.811
2008 Connor MR, Liao JC. Engineering of an Escherichia coli strain for the production of 3-methyl-1-butanol. Applied and Environmental Microbiology. 74: 5769-75. PMID 18676713 DOI: 10.1128/Aem.00468-08  0.73
2008 Bernstein JR, Bulter T, Liao JC. Transfer of the high-GC cyclohexane carboxylate degradation pathway from Rhodopseudomonas palustris to Escherichia coli for production of biotin. Metabolic Engineering. 10: 131-40. PMID 18396082 DOI: 10.1016/J.Ymben.2008.02.001  0.703
2008 Atsumi S, Hanai T, Liao JC. Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature. 451: 86-9. PMID 18172501 DOI: 10.1038/Nature06450  0.597
2008 Jarboe LR, Hyduke DR, Tran LM, Chou KJ, Liao JC. Determination of the Escherichia coli S-nitrosoglutathione response network using integrated biochemical and systems analysis. The Journal of Biological Chemistry. 283: 5148-57. PMID 18070885 DOI: 10.1074/Jbc.M706018200  0.799
2008 Chou KJ, Dodd J, Liao JC. Interactions of nitrosylhemoglobin and carboxyhemoglobin with erythrocyte. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 18: 122-35. PMID 18047843 DOI: 10.1016/J.Niox.2007.10.006  0.534
2008 Sriram G, Rahib L, He JS, Campos AE, Parr LS, Liao JC, Dipple KM. Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells. Molecular Genetics and Metabolism. 93: 145-59. PMID 18029214 DOI: 10.1016/J.Ymgme.2007.09.008  0.363
2008 Atsumi S, Cann AF, Connor MR, Shen CR, Smith KM, Brynildsen MP, Chou KJ, Hanai T, Liao JC. Metabolic engineering of Escherichia coli for 1-butanol production. Metabolic Engineering. 10: 305-11. PMID 17942358 DOI: 10.1016/J.Ymben.2007.08.003  0.798
2007 Hanai T, Atsumi S, Liao JC. Engineered synthetic pathway for isopropanol production in Escherichia coli. Applied and Environmental Microbiology. 73: 7814-8. PMID 17933911 DOI: 10.1128/Aem.01140-07  0.625
2007 Wong WW, Tsai TY, Liao JC. Single-cell zeroth-order protein degradation enhances the robustness of synthetic oscillator. Molecular Systems Biology. 3: 130. PMID 17667952 DOI: 10.1038/Msb4100172  0.302
2007 Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge JP, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, et al. Differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice. A novel biomarker of atherosclerosis. The Journal of Biological Chemistry. 282: 23698-707. PMID 17556366 DOI: 10.1074/Jbc.M702163200  0.526
2007 Brynildsen MP, Wu TY, Jang SS, Liao JC. Biological network mapping and source signal deduction. Bioinformatics (Oxford, England). 23: 1783-91. PMID 17495996 DOI: 10.1093/Bioinformatics/Btm246  0.654
2007 Hyduke DR, Jarboe LR, Tran LM, Chou KJ, Liao JC. Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 104: 8484-9. PMID 17494765 DOI: 10.1073/Pnas.0610888104  0.791
2007 Bernstein JR, Bulter T, Shen CR, Liao JC. Directed evolution of ribosomal protein S1 for enhanced translational efficiency of high GC Rhodopseudomonas palustris DNA in Escherichia coli. The Journal of Biological Chemistry. 282: 18929-36. PMID 17412688 DOI: 10.1074/Jbc.M701395200  0.662
2007 Rahib L, MacLennan NK, Horvath S, Liao JC, Dipple KM. Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling. European Journal of Human Genetics : Ejhg. 15: 646-57. PMID 17406644 DOI: 10.1038/Sj.Ejhg.5201801  0.334
2007 Han TH, Perloff JK, Liao JC. Nitric oxide metabolism in adults with cyanotic congenital heart disease. The American Journal of Cardiology. 99: 691-5. PMID 17317373 DOI: 10.1016/J.Amjcard.2006.10.024  0.521
2006 Braatsch S, Bernstein JR, Lessner F, Morgan J, Liao JC, Harwood CS, Beatty JT. Rhodopseudomonas palustris CGA009 has two functional ppsR genes, each of which encodes a repressor of photosynthesis gene expression. Biochemistry. 45: 14441-51. PMID 17128983 DOI: 10.1021/Bi061074B  0.658
2006 Brynildsen MP, Tran LM, Liao JC. A Gibbs sampler for the identification of gene expression and network connectivity consistency. Bioinformatics (Oxford, England). 22: 3040-6. PMID 17060361 DOI: 10.1093/Bioinformatics/Btl541  0.731
2006 Brynildsen MP, Tran LM, Liao JC. Versatility and connectivity efficiency of bipartite transcription networks. Biophysical Journal. 91: 2749-59. PMID 16815895 DOI: 10.1529/Biophysj.106.082560  0.721
2006 Galbraith SJ, Tran LM, Liao JC. Transcriptome network component analysis with limited microarray data. Bioinformatics (Oxford, England). 22: 1886-94. PMID 16766556 DOI: 10.1093/Bioinformatics/Btl279  0.576
2006 Wong WW, Liao JC. The design of intracellular oscillators that interact with metabolism. Cellular and Molecular Life Sciences : Cmls. 63: 1215-20. PMID 16649146 DOI: 10.1007/S00018-005-5611-4  0.337
2006 MacLennan NK, Rahib L, Shin C, Fang Z, Horvath S, Dean J, Liao JC, McCabe ER, Dipple KM. Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity. Human Molecular Genetics. 15: 405-15. PMID 16368706 DOI: 10.1093/Hmg/Ddi457  0.714
2006 Liao JC. Systems Biology: Where Does Chemical Engineering Stand? Journal of the Chinese Institute of Chemical Engineers. 37: 103-106. DOI: 10.6967/Jcice.200601.0103  0.306
2005 Boscolo R, Sabatti C, Liao JC, Roychowdhury VP. A generalized framework for network component analysis. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 2: 289-301. PMID 17044167 DOI: 10.1109/Tcbb.2005.47  0.317
2005 Brynildsen MP, Wong WW, Liao JC. Transcriptional regulation and metabolism. Biochemical Society Transactions. 33: 1423-6. PMID 16246136 DOI: 10.1042/Bst20051423  0.689
2005 Kao KC, Tran LM, Liao JC. A global regulatory role of gluconeogenic genes in Escherichia coli revealed by transcriptome network analysis. The Journal of Biological Chemistry. 280: 36079-87. PMID 16141204 DOI: 10.1074/Jbc.M508202200  0.733
2005 Rohlin L, Trent JD, Salmon K, Kim U, Gunsalus RP, Liao JC. Heat shock response of Archaeoglobus fulgidus. Journal of Bacteriology. 187: 6046-57. PMID 16109946 DOI: 10.1128/Jb.187.17.6046-6057.2005  0.752
2005 Yang YL, Liao JC. Determination of functional interactions among signalling pathways in Escherichia coli K-12. Metabolic Engineering. 7: 280-90. PMID 16002309 DOI: 10.1016/J.Ymben.2005.05.002  0.306
2005 Yang YL, Suen J, Brynildsen MP, Galbraith SJ, Liao JC. Inferring yeast cell cycle regulators and interactions using transcription factor activities. Bmc Genomics. 6: 90. PMID 15949038 DOI: 10.1186/1471-2164-6-90  0.635
2005 Sriram G, Martinez JA, McCabe ER, Liao JC, Dipple KM. Single-gene disorders: what role could moonlighting enzymes play? American Journal of Human Genetics. 76: 911-24. PMID 15877277 DOI: 10.1086/430799  0.317
2005 Fung E, Wong WW, Suen JK, Bulter T, Lee SG, Liao JC. A synthetic gene-metabolic oscillator. Nature. 435: 118-22. PMID 15875027 DOI: 10.1038/Nature03508  0.598
2005 Tran LM, Brynildsen MP, Kao KC, Suen JK, Liao JC. gNCA: a framework for determining transcription factor activity based on transcriptome: identifiability and numerical implementation. Metabolic Engineering. 7: 128-41. PMID 15781421 DOI: 10.1016/J.Ymben.2004.12.001  0.784
2005 Han TH, Pelling A, Jeon TJ, Gimzewski JK, Liao JC. Erythrocyte nitric oxide transport reduced by a submembrane cytoskeletal barrier. Biochimica Et Biophysica Acta. 1723: 135-42. PMID 15777627 DOI: 10.1016/J.Bbagen.2005.01.013  0.49
2005 Zhou B, Beckwith D, Jarboe LR, Liao JC. Markov Chain modeling of pyelonephritis-associated pili expression in uropathogenic Escherichia coli. Biophysical Journal. 88: 2541-53. PMID 15681643 DOI: 10.1529/Biophysj.104.052126  0.646
2005 Hyduke DR, Liao JC. Analysis of nitric oxide donor effectiveness in resistance vessels. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2390-9. PMID 15653763 DOI: 10.1152/Ajpheart.00990.2004  0.661
2005 Sabatti C, Rohlin L, Lange K, Liao JC. Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites. Bioinformatics (Oxford, England). 21: 922-31. PMID 15509602 DOI: 10.1093/Bioinformatics/Bti083  0.736
2005 Han TH, Pelling A, Jeon T, Gimzewski JK, Liao JC. Corrigendum to “Erythrocyte nitric oxide transport reduced by a submembrane cytoskeletal barrier” [Biochim. Biophys. Acta 1723 (2005) 135_142] Biochimica Et Biophysica Acta (Bba) - General Subjects. 1726: 336. DOI: 10.1016/J.Bbagen.2005.11.001  0.46
2004 Jarboe LR, Beckwith D, Liao JC. Stochastic modeling of the phase-variable pap operon regulation in uropathogenic Escherichia coli. Biotechnology and Bioengineering. 88: 189-203. PMID 15449298 DOI: 10.1002/Bit.20228  0.646
2004 Liao JC. Custom design of metabolism. Nature Biotechnology. 22: 823-4. PMID 15229541 DOI: 10.1038/Nbt0704-823  0.32
2004 Han TH, Fukuto JM, Liao JC. Reductive nitrosylation and S-nitrosation of hemoglobin in inhomogeneous nitric oxide solutions. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 10: 74-82. PMID 15135360 DOI: 10.1016/J.Niox.2004.03.003  0.501
2004 Bulter T, Lee SG, Wong WW, Fung E, Connor MR, Liao JC. Design of artificial cell-cell communication using gene and metabolic networks. Proceedings of the National Academy of Sciences of the United States of America. 101: 2299-304. PMID 14983004 DOI: 10.1073/Pnas.0306484101  0.764
2004 Kao KC, Yang YL, Boscolo R, Sabatti C, Roychowdhury V, Liao JC. Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli by using network component analysis. Proceedings of the National Academy of Sciences of the United States of America. 101: 641-6. PMID 14694202 DOI: 10.1073/Pnas.0305287101  0.624
2003 Bulter T, Bernstein JR, Liao JC. A perspective of metabolic engineering strategies: moving up the systems hierarchy. Biotechnology and Bioengineering. 84: 815-21. PMID 14708122 DOI: 10.1002/Bit.10845  0.696
2003 Liao JC, Boscolo R, Yang YL, Tran LM, Sabatti C, Roychowdhury VP. Network component analysis: reconstruction of regulatory signals in biological systems. Proceedings of the National Academy of Sciences of the United States of America. 100: 15522-7. PMID 14673099 DOI: 10.1073/Pnas.2136632100  0.548
2003 Hyduke DR, Rohlin L, Kao KC, Liao JC. A software package for cDNA microarray data normalization and assessing confidence intervals. Omics : a Journal of Integrative Biology. 7: 227-34. PMID 14583113 DOI: 10.1089/153623103322452369  0.762
2003 Han TH, Qamirani E, Nelson AG, Hyduke DR, Chaudhuri G, Kuo L, Liao JC. Regulation of nitric oxide consumption by hypoxic red blood cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 12504-9. PMID 14523233 DOI: 10.1073/Pnas.2133409100  0.742
2003 Wang C, Han TH, Liao JC. Sequence Analysis for Metabolic Evolution of Archaeoglobus fulgidus Geranylgeranyl Diphosphate Synthase in Escherichia coli for Carotenoid Biosynthesis Journal of the Chinese Institute of Chemical Engineers. 34: 47-56. DOI: 10.6967/Jcice.200301.0047  0.754
2002 Hatzimanikatis V, Liao JC. A memorial review of Jay Bailey's contribution in prokaryotic metabolic engineering. Biotechnology and Bioengineering. 79: 504-8. PMID 12209822 DOI: 10.1002/Bit.10406  0.314
2002 Joshi MS, Ferguson TB, Han TH, Hyduke DR, Liao JC, Rassaf T, Bryan N, Feelisch M, Lancaster JR. Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions. Proceedings of the National Academy of Sciences of the United States of America. 99: 10341-6. PMID 12124398 DOI: 10.1073/Pnas.152149699  0.72
2002 Sabatti C, Rohlin L, Oh MK, Liao JC. Co-expression pattern from DNA microarray experiments as a tool for operon prediction. Nucleic Acids Research. 30: 2886-93. PMID 12087173 DOI: 10.1093/Nar/Gkf388  0.784
2002 Han TH, Hyduke DR, Vaughn MW, Fukuto JM, Liao JC. Nitric oxide reaction with red blood cells and hemoglobin under heterogeneous conditions. Proceedings of the National Academy of Sciences of the United States of America. 99: 7763-8. PMID 12032357 DOI: 10.1073/Pnas.122118299  0.736
2002 Oh MK, Rohlin L, Kao KC, Liao JC. Global expression profiling of acetate-grown Escherichia coli. The Journal of Biological Chemistry. 277: 13175-83. PMID 11815613 DOI: 10.1074/Jbc.M110809200  0.811
2002 Rohlin L, Oh M, Liao JC. DNA Microarray for Microbial Biotechnology: Gene Expression Profiles in Escherichia coli during Protein Overexpression Journal of the Chinese Institute of Chemical Engineers. 33: 103-112. DOI: 10.6967/Jcice.200201.0103  0.801
2001 Farmer WR, Liao JC. Acetate-inducible protein overexpression from the glnAp2 promoter of Escherichia coli. Biotechnology and Bioengineering. 75: 504-9. PMID 11745125 DOI: 10.1002/Bit.10049  0.8
2001 Huang KT, Han TH, Hyduke DR, Vaughn MW, Van Herle H, Hein TW, Zhang C, Kuo L, Liao JC. Modulation of nitric oxide bioavailability by erythrocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 11771-6. PMID 11573011 DOI: 10.1073/Pnas.201276698  0.715
2001 Wang CW, Liao JC. Alteration of product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution. The Journal of Biological Chemistry. 276: 41161-4. PMID 11526111 DOI: 10.1074/Jbc.M105786200  0.72
2001 Tseng GC, Oh MK, Rohlin L, Liao JC, Wong WH. Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects. Nucleic Acids Research. 29: 2549-57. PMID 11410663 DOI: 10.1093/Nar/29.12.2549  0.779
2001 Rohlin L, Oh MK, Liao JC. Microbial pathway engineering for industrial processes: evolution, combinatorial biosynthesis and rational design. Current Opinion in Microbiology. 4: 330-5. PMID 11378488 DOI: 10.1016/S1369-5274(00)00213-7  0.802
2001 Farmer WR, Liao JC. Precursor balancing for metabolic engineering of lycopene production in Escherichia coli. Biotechnology Progress. 17: 57-61. PMID 11170480 DOI: 10.1021/Bp000137T  0.807
2001 Barkovich R, Liao JC. Metabolic engineering of isoprenoids Metabolic Engineering. 3: 27-39. PMID 11162230 DOI: 10.1006/Mben.2000.0168  0.412
2000 Wang C, Oh MK, Liao JC. Directed evolution of metabolically engineered Escherichia coli for carotenoid production. Biotechnology Progress. 16: 922-6. PMID 11101317 DOI: 10.1021/Bp000124F  0.785
2000 Oh MK, Liao JC. DNA microarray detection of metabolic responses to protein overproduction in Escherichia coli. Metabolic Engineering. 2: 201-9. PMID 11056062 DOI: 10.1006/Mben.2000.0149  0.567
2000 Farmer WR, Liao JC. Improving lycopene production in Escherichia coli by engineering metabolic control. Nature Biotechnology. 18: 533-7. PMID 10802621 DOI: 10.1038/75398  0.809
2000 Oh MK, Liao JC. Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli. Biotechnology Progress. 16: 278-86. PMID 10753455 DOI: 10.1021/Bp000002N  0.575
1999 Liao JC, Oh MK. Toward predicting metabolic fluxes in metabolically engineered strains. Metabolic Engineering. 1: 214-23. PMID 10937936 DOI: 10.1006/Mben.1999.0121  0.565
1999 Wang CW, Oh MK, Liao JC. Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli. Biotechnology and Bioengineering. 62: 235-41. PMID 10099534 DOI: 10.1002/(Sici)1097-0290(19990120)62:2<235::Aid-Bit14>3.0.Co;2-U  0.63
1999 Lee B, Yen J, Yang L, Liao JC. Incorporating qualitative knowledge in enzyme kinetic models using fuzzy logic. Biotechnology and Bioengineering. 62: 722-9. PMID 9951527 DOI: 10.1002/(Sici)1097-0290(19990320)62:6<722::Aid-Bit11>3.0.Co;2-U  0.332
1999 Liao JC. Inverse flux analysis Journal of Biotechnology. 71: 259-262. DOI: 10.1016/S0168-1656(99)00031-0  0.362
1998 Chang CI, Liao JC, Kuo L. Arginase modulates nitric oxide production in activated macrophages American Journal of Physiology - Heart and Circulatory Physiology. 274. PMID 9458885 DOI: 10.1152/Ajpheart.1998.274.1.H342  0.317
1998 Liao JC, Delgado J. Flux calculation using metabolic control constraints Biotechnology Progress. 14: 554-560. DOI: 10.1021/Bp980056L  0.331
1997 Delgado J, Liao JC. Inverse flux analysis for reduction of acetate excretion in Escherichia coli Biotechnology Progress. 13: 361-367. PMID 9265774 DOI: 10.1021/Bp970047X  0.386
1997 Farmer WR, Liao JC. Reduction of aerobic acetate production by Escherichia coli. Applied and Environmental Microbiology. 63: 3205-10. PMID 9251207 DOI: 10.1128/Aem.63.8.3205-3210.1997  0.805
1996 Hung S, Liao JC. Effects of ultraviolet light irradiation in biotreatment of organophosphates Applied Biochemistry and Biotechnology. 56: 37-47. PMID 8607607 DOI: 10.1007/Bf02787868  0.32
1996 Farmer WR, Liao JC. Progress in metabolic engineering Current Opinion in Biotechnology. 7: 198-204. DOI: 10.1016/S0958-1669(96)80013-9  0.805
1996 Tan HL, Delgado J, Liao JC. Extension of metabolic control analysis to chemostat bioreactors Aiche Journal. 42: 1454-1464. DOI: 10.1002/Aic.690420526  0.334
1995 Delgado J, Liao JC. Control of metabolic pathways by time-scale separation Biosystems. 36: 55-70. PMID 8527696 DOI: 10.1016/0303-2647(95)01528-S  0.322
1994 Patnaik R, Liao JC. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield Applied and Environmental Microbiology. 60: 3903-3908. PMID 7993080 DOI: 10.1128/Aem.60.11.3903-3908.1994  0.441
1994 Liao JC, Chao YP, Patnaik R. Alteration of the biochemical valves in the central metabolism of escherichia coli Annals of the New York Academy of Sciences. 745: 21-34. PMID 7832509 DOI: 10.1111/J.1749-6632.1994.Tb44361.X  0.425
1993 Chao YP, Liao JC. Alteration of growth yield by overexpression of phosphoenolpyruvate carboxylase and phosphoenolpyruvate carboxykinase in Escherichia coli Applied and Environmental Microbiology. 59: 4261-4265. PMID 8285716 DOI: 10.1128/Aem.59.12.4261-4265.1993  0.384
1993 Chao YP, Patnaik R, Roof WD, Young RF, Liao JC. Control of gluconeogenic growth by pps and pck in Escherichia coli Journal of Bacteriology. 175: 6939-6944. PMID 8226637 DOI: 10.1128/Jb.175.21.6939-6944.1993  0.313
1993 Liao JC. Modelling and analysis of metabolic pathways Current Opinion in Biotechnology. 4: 211-216. PMID 7763572 DOI: 10.1016/0958-1669(93)90127-I  0.369
1993 Liao JC, Delgado J. Advances in metabolic control analysis Biotechnology Progress. 9: 221-233. DOI: 10.1021/Bp00021A001  0.329
1992 Delgado J, Liao JC. Determination of flux control coefficients from transient metabolite concentrations Biochemical Journal. 282: 919-927. PMID 1554375 DOI: 10.1042/Bj2820919  0.352
1992 Liao JC, Delgado J. Dynamic metabolic control theory: A methodology for investigating metabolic regulation using transient metabolic data Annals of the New York Academy of Sciences. 665: 27-38. PMID 1416609 DOI: 10.1111/J.1749-6632.1992.Tb42571.X  0.319
1992 Patnaik R, Roof WD, Young RF, Liao JC. Stimulation of glucose catabolism in Escherichia coli by a potential futile cycle Journal of Bacteriology. 174: 7527-7532. PMID 1332936 DOI: 10.1128/Jb.174.23.7527-7532.1992  0.309
1991 Delgado JP, Liao JC. Identifying rate-controlling enzymes in metabolic pathways without kinetic parameters Biotechnology Progress. 7: 15-20. DOI: 10.1021/Bp00007A003  0.341
1988 Liao JC, Lightfoot EN. Lumping analysis of biochemical reaction systems with time scale separation. Biotechnology and Bioengineering. 31: 869-79. PMID 18584692 DOI: 10.1002/Bit.260310815  0.541
1988 Liao JC, Lightfoot EN, Jolly SO, Jacobson GK. Application of characteristic reaction paths: Rate-limiting capability of phosphofructokinase in yeast fermentation. Biotechnology and Bioengineering. 31: 855-68. PMID 18584691 DOI: 10.1002/Bit.260310814  0.57
1988 Liao JC, Lightfoot EN. Characteristic reaction paths of biochemical reaction systems with time scale separation. Biotechnology and Bioengineering. 31: 847-54. PMID 18584690 DOI: 10.1002/Bit.260310813  0.548
1987 Liao JC, Lightfoot EN. Extending the quasi-steady state concept to analysis of metabolic networks. Journal of Theoretical Biology. 126: 253-73. PMID 3657233 DOI: 10.1016/S0022-5193(87)80234-5  0.596
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