| Year |
Citation |
Score |
| 2022 |
Perego M, Fu S, Cao Y, Kossenkov A, Yao M, Alicea-Torres K, Liu W, Jiang Z, Chen Z, Fuchs SY, Zhou J, Gabrilovich DI. Mechanisms regulating transitory suppressive activity of neutrophils in newborns: PMNs-MDSCs in newborns. Journal of Leukocyte Biology. PMID 35726818 DOI: 10.1002/JLB.4HI0921-514RR |
0.373 |
|
| 2021 |
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, et al. SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway. Journal of Virology. JVI0086221. PMID 34260266 DOI: 10.1128/JVI.00862-21 |
0.304 |
|
| 2021 |
Alicea-Torres K, Sanseviero E, Gui J, Chen J, Veglia F, Yu Q, Donthireddy L, Kossenkov A, Lin C, Fu S, Mulligan C, Nam B, Masters G, Denstman F, Bennett J, ... Fuchs SY, et al. Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway. Nature Communications. 12: 1717. PMID 33741967 DOI: 10.1038/s41467-021-22033-2 |
0.323 |
|
| 2020 |
Odnokoz O, Yu P, Peck AR, Sun Y, Kovatich AJ, Hooke JA, Hu H, Mitchell EP, Rui H, Fuchs SY. Malignant cell-specific pro-tumorigenic role of type I interferon receptor in breast cancers. Cancer Biology & Therapy. 1-8. PMID 32378445 DOI: 10.1080/15384047.2020.1750297 |
0.353 |
|
| 2020 |
Singh S, Kumar S, Srivastava RK, Nandi A, Thacker G, Murali H, Kim S, Baldeon M, Tobias J, Blanco MA, Saffie R, Zaidi MR, Sinha S, Busino L, Fuchs SY, et al. Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling. Nature Cell Biology. PMID 32284542 DOI: 10.1038/S41556-020-0495-Y |
0.32 |
|
| 2020 |
Fuchs S, Alicea-Torres KM, Gabrilovich DI. Abstract A72: IFNAR1 signaling regulates PMN-MDSCs immune suppressive activity in cancer Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-A72 |
0.369 |
|
| 2019 |
Gui J, Katlinski KV, Koumenis C, Diehl JA, Fuchs SY. The PKR-like endoplasmic reticulum kinase promotes the dissemination of Myc-induced leukemic cells. Molecular Cancer Research : McR. PMID 30902831 DOI: 10.1158/1541-7786.Mcr-19-0002 |
0.371 |
|
| 2017 |
Gui J, Zhao B, Lyu K, Tong W, Fuchs SY. Downregulation of the IFNAR1 chain of type 1 interferon receptor contributes to the maintenance of the hematopoietic stem cells. Cancer Biology & Therapy. 0. PMID 28678581 DOI: 10.1080/15384047.2017.1345395 |
0.375 |
|
| 2017 |
Zhao B, Bhattacharya S, Yu Q, Fuchs SY. Expression of the IFNAR1 chain of type 1 interferon receptor in benign cells protects against progression of acute leukemia. Leukemia & Lymphoma. 1-7. PMID 28503979 DOI: 10.1080/10428194.2017.1319053 |
0.38 |
|
| 2016 |
Katlinskaya YV, Katlinski KV, Yu Q, Ortiz A, Beiting DP, Brice A, Davar D, Sanders C, Kirkwood JM, Rui H, Xu X, Koumenis C, Diehl JA, Fuchs SY. Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Reports. PMID 27052162 DOI: 10.1016/J.Celrep.2016.03.006 |
0.32 |
|
| 2015 |
Katlinskaya YV, Carbone CJ, Yu Q, Fuchs SY. Type 1 interferons contribute to the clearance of senescent cell. Cancer Biology & Therapy. 16: 1214-9. PMID 26046815 DOI: 10.1080/15384047.2015.1056419 |
0.312 |
|
| 2014 |
Carbone CJ, Fuchs SY. Eliminative signaling by Janus kinases: role in the downregulation of associated receptors. Journal of Cellular Biochemistry. 115: 8-16. PMID 23959845 DOI: 10.1002/Jcb.24647 |
0.437 |
|
| 2013 |
Zheng H, Gupta V, Patterson-Fortin J, Bhattacharya S, Katlinski K, Wu J, Varghese B, Carbone CJ, Aressy B, Fuchs SY, Greenberg RA. A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Reports. 5: 180-93. PMID 24075985 DOI: 10.1016/J.Celrep.2013.08.025 |
0.735 |
|
| 2013 |
Fuchs SY. Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 211-25. PMID 23570388 DOI: 10.1089/jir.2012.0117 |
0.322 |
|
| 2013 |
Xu J, Sun D, Jiang J, Deng L, Zhang Y, Yu H, Bahl D, Langenheim JF, Chen WY, Fuchs SY, Frank SJ. The role of prolactin receptor in GH signaling in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 27: 266-79. PMID 23192981 DOI: 10.1210/Me.2012-1297 |
0.41 |
|
| 2013 |
Bhattacharya S, HuangFu WC, Dong G, Qian J, Baker DP, Karar J, Koumenis C, Diehl JA, Fuchs SY. Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses. Oncogene. 32: 4214-21. PMID 23045272 DOI: 10.1038/onc.2012.439 |
0.428 |
|
| 2013 |
Koumenis C, Hart LS, Cunningham T, Dey S, Tameire F, Mills I, Ruggero D, Diehl AJ, Fuchs S. Abstract SY32-04: The translation initiation factor elF2α regulates cytoprotective autophagy in Myc-dependent lymphoma. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy32-04 |
0.409 |
|
| 2013 |
Carbone CJ, Varghese B, Zheng H, Fuchs SY. 33 Cytokine. 63: 251. DOI: 10.1016/J.Cyto.2013.06.036 |
0.741 |
|
| 2012 |
Carbone CJ, Zheng H, Bhattacharya S, Lewis JR, Reiter AM, Henthorn P, Zhang ZY, Baker DP, Ukkiramapandian R, Bence KK, Fuchs SY. Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies. Proceedings of the National Academy of Sciences of the United States of America. 109: 19226-31. PMID 23129613 DOI: 10.1073/Pnas.1211491109 |
0.448 |
|
| 2012 |
Fuchs SY. Ubiquitination-mediated regulation of interferon responses. Growth Factors (Chur, Switzerland). 30: 141-8. PMID 22394219 DOI: 10.3109/08977194.2012.669382 |
0.316 |
|
| 2012 |
Cho IR, Oh M, Koh SS, Malilas W, Srisuttee R, Jhun BH, Pellegrini S, Fuchs SY, Chung YH. Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor. International Journal of Molecular Medicine. 29: 581-6. PMID 22218495 DOI: 10.3892/ijmm.2012.879 |
0.318 |
|
| 2012 |
Huangfu WC, Qian J, Liu C, Liu J, Lokshin AE, Baker DP, Rui H, Fuchs SY. Inflammatory signaling compromises cell responses to interferon alpha. Oncogene. 31: 161-72. PMID 21666722 DOI: 10.1038/Onc.2011.221 |
0.372 |
|
| 2011 |
Zheng H, Qian J, Baker DP, Fuchs SY. Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor. The Journal of Biological Chemistry. 286: 35733-41. PMID 21865166 DOI: 10.1074/jbc.M111.263608 |
0.463 |
|
| 2011 |
Zheng H, Qian J, Carbone CJ, Leu NA, Baker DP, Fuchs SY. Vascular endothelial growth factor-induced elimination of the type 1 interferon receptor is required for efficient angiogenesis. Blood. 118: 4003-6. PMID 21832278 DOI: 10.1182/Blood-2011-06-359745 |
0.338 |
|
| 2011 |
Bhattacharya S, Zheng H, Tzimas C, Carroll M, Baker DP, Fuchs SY. Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFNα via accelerating the degradation of its receptor. Blood. 118: 4179-87. PMID 21821707 DOI: 10.1182/Blood-2010-12-325373 |
0.441 |
|
| 2011 |
Qian J, Zheng H, Huangfu WC, Liu J, Carbone CJ, Leu NA, Baker DP, Fuchs SY. Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1. Plos Pathogens. 7: e1002065. PMID 21695243 DOI: 10.1371/Journal.Ppat.1002065 |
0.409 |
|
| 2011 |
Bhattacharya S, Qian J, Tzimas C, Baker DP, Koumenis C, Diehl JA, Fuchs SY. Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor. The Journal of Biological Chemistry. 286: 22069-76. PMID 21540188 DOI: 10.1074/Jbc.M111.238766 |
0.441 |
|
| 2011 |
Zheng H, Qian J, Varghese B, Baker DP, Fuchs S. Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2. Molecular and Cellular Biology. 31: 710-20. PMID 21173164 DOI: 10.1128/Mcb.01154-10 |
0.764 |
|
| 2011 |
Hart LS, Cunningham T, Datta T, Liu H, Koong AC, Fuchs S, Diehl JA, Ruggero D, Koumenis C. Abstract 2078: PERK-mediated autophagy promotes Myc-induced transformation and tumorigenesis Cancer Research. 71: 2078-2078. DOI: 10.1158/1538-7445.Am2011-2078 |
0.362 |
|
| 2010 |
HuangFu WC, Qian J, Liu C, Rui H, Fuchs SY. Melanoma cell-secreted soluble factor that stimulates ubiquitination and degradation of the interferon alpha receptor and attenuates its signaling. Pigment Cell & Melanoma Research. 23: 838-40. PMID 21644263 DOI: 10.1111/J.1755-148X.2010.00770.X |
0.386 |
|
| 2010 |
Huangfu WC, Fuchs SY. Ubiquitination-dependent regulation of signaling receptors in cancer. Genes & Cancer. 1: 725-34. PMID 21127735 DOI: 10.1177/1947601910382901 |
0.429 |
|
| 2010 |
Varghese B, Swaminathan G, Plotnikov A, Tzimas C, Yang N, Rui H, Fuchs SY. Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation. Molecular Endocrinology (Baltimore, Md.). 24: 2356-65. PMID 20962042 DOI: 10.1210/Me.2010-0219 |
0.753 |
|
| 2010 |
Bhattacharya S, HuangFu WC, Liu J, Veeranki S, Baker DP, Koumenis C, Diehl JA, Fuchs SY. Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor. The Journal of Biological Chemistry. 285: 2318-25. PMID 19948722 DOI: 10.1074/Jbc.M109.071498 |
0.457 |
|
| 2010 |
Fuchs SY. SS10-2 Phosphorylation-dependent regulation of IFNAR1 stability and signaling Cytokine. 52: 78. DOI: 10.1016/j.cyto.2010.07.324 |
0.314 |
|
| 2010 |
Zheng H, Qian J, Varghese B, Baker DP, Fuchs S. PS2-36 Limiting cellular responses to interferon alpha: Role of protein kinase D2 Cytokine. 52: 58. DOI: 10.1016/J.Cyto.2010.07.241 |
0.717 |
|
| 2010 |
HuangFu W, Qian J, Liu C, Liu J, Ilyin V, Baker DP, Loksin AE, Rui H, Fuchs S. PS1-55 Cytokine signaling compromises the sensitivity of melanoma to Type I interferons Cytokine. 52: 28-29. DOI: 10.1016/J.Cyto.2010.07.127 |
0.338 |
|
| 2009 |
Liu J, Carvalho LP, Bhattacharya S, Carbone CJ, Kumar KG, Leu NA, Yau PM, Donald RG, Weiss MJ, Baker DP, McLaughlin KJ, Scott P, Fuchs SY. Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. Molecular and Cellular Biology. 29: 6401-12. PMID 19805514 DOI: 10.1128/Mcb.00478-09 |
0.46 |
|
| 2009 |
Plotnikov A, Varghese B, Tran TH, Liu C, Rui H, Fuchs SY. Impaired turnover of prolactin receptor contributes to transformation of human breast cells. Cancer Research. 69: 3165-72. PMID 19276348 DOI: 10.1158/0008-5472.Can-08-4033 |
0.736 |
|
| 2009 |
Liu J, HuangFu WC, Kumar KG, Qian J, Casey JP, Hamanaka RB, Grigoriadou C, Aldabe R, Diehl JA, Fuchs SY. Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor. Cell Host & Microbe. 5: 72-83. PMID 19154989 DOI: 10.1016/J.Chom.2008.11.008 |
0.374 |
|
| 2008 |
Frank SJ, Fuchs SY. Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system. Biochimica Et Biophysica Acta. 1782: 785-94. PMID 18586085 DOI: 10.1016/J.Bbadis.2008.06.001 |
0.342 |
|
| 2008 |
Varghese B, Barriere H, Carbone CJ, Banerjee A, Swaminathan G, Plotnikov A, Xu P, Peng J, Goffin V, Lukacs GL, Fuchs SY. Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. Molecular and Cellular Biology. 28: 5275-87. PMID 18573876 DOI: 10.1128/Mcb.00350-08 |
0.763 |
|
| 2008 |
Kumar KG, Varghese B, Banerjee A, Baker DP, Constantinescu SN, Pellegrini S, Fuchs SY. Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif. The Journal of Biological Chemistry. 283: 18566-72. PMID 18474601 DOI: 10.1074/Jbc.M800991200 |
0.767 |
|
| 2008 |
Plotnikov A, Li Y, Tran TH, Tang W, Palazzo JP, Rui H, Fuchs SY. Oncogene-mediated inhibition of glycogen synthase kinase 3 beta impairs degradation of prolactin receptor. Cancer Research. 68: 1354-61. PMID 18316598 DOI: 10.1158/0008-5472.Can-07-6094 |
0.403 |
|
| 2008 |
Swaminathan G, Varghese B, Thangavel C, Carbone CJ, Plotnikov A, Kumar KG, Jablonski EM, Clevenger CV, Goffin V, Deng L, Frank SJ, Fuchs SY. Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2. The Journal of Endocrinology. 196: R1-7. PMID 18252943 DOI: 10.1677/Joe-07-0554 |
0.772 |
|
| 2008 |
Swaminathan G, Varghese B, Fuchs SY. Regulation of prolactin receptor levels and activity in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 13: 81-91. PMID 18204982 DOI: 10.1007/S10911-008-9068-6 |
0.737 |
|
| 2008 |
Liu J, Plotnikov A, Banerjee A, Suresh Kumar KG, Ragimbeau J, Marijanovic Z, Baker DP, Pellegrini S, Fuchs SY. Ligand-independent pathway that controls stability of interferon alpha receptor. Biochemical and Biophysical Research Communications. 367: 388-93. PMID 18166147 DOI: 10.1016/j.bbrc.2007.12.137 |
0.487 |
|
| 2008 |
Liu J, HuangFu W, Kumar KGS, Casey JP, Hamanaka R, Grigoriadou C, Aldabe R, Diehl JA, Fuchs SY. 371 Virus-induced unfolded protein response attenuates anti-viral defenses via phosphorylation-dependent ubiquitination and degradation of Type I interferon receptor Cytokine. 43: 331-331. DOI: 10.1016/J.Cyto.2008.07.456 |
0.323 |
|
| 2007 |
Kumar KG, Barriere H, Carbone CJ, Liu J, Swaminathan G, Xu P, Li Y, Baker DP, Peng J, Lukacs GL, Fuchs SY. Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. The Journal of Cell Biology. 179: 935-50. PMID 18056411 DOI: 10.1083/Jcb.200706034 |
0.459 |
|
| 2007 |
Kumar KG, Liu J, Li Y, Yu D, Thomas-Tikhonenko A, Herlyn M, Fuchs SY. Raf inhibitor stabilizes receptor for the type I interferon but inhibits its anti-proliferative effects in human malignant melanoma cells. Cancer Biology & Therapy. 6: 1437-41. PMID 17873516 DOI: 10.4161/Cbt.6.9.4569 |
0.399 |
|
| 2007 |
Deng L, He K, Wang X, Yang N, Thangavel C, Jiang J, Fuchs SY, Frank SJ. Determinants of growth hormone receptor down-regulation. Molecular Endocrinology (Baltimore, Md.). 21: 1537-51. PMID 17488973 DOI: 10.1210/Me.2007-0138 |
0.432 |
|
| 2007 |
Liu J, Kumar KGS, Carvalho L, Donald RGK, Scott P, Fuchs SY. 89 Regulation of Type I Interferon Receptor Stability and Signaling by Casein Kinase 1-alpha and its Leishmania Orthologue Cytokine. 39: 25-25. DOI: 10.1016/J.Cyto.2007.07.094 |
0.4 |
|
| 2006 |
Malakhova OA, Kim KI, Luo JK, Zou W, Kumar KG, Fuchs SY, Shuai K, Zhang DE. UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. The Embo Journal. 25: 2358-67. PMID 16710296 DOI: 10.1038/Sj.Emboj.7601149 |
0.405 |
|
| 2006 |
Marijanovic Z, Ragimbeau J, Kumar KG, Fuchs SY, Pellegrini S. TYK2 activity promotes ligand-induced IFNAR1 proteolysis. The Biochemical Journal. 397: 31-8. PMID 16551269 DOI: 10.1042/BJ20060272 |
0.452 |
|
| 2006 |
Li Y, Clevenger CV, Minkovsky N, Kumar K, Raghunath PN, Tomaszewski JE, Spiegelman VS, Fuchs SY. Stabilization of prolactin receptor in breast cancer cells Oncogene. 25: 1896-1902. PMID 16278670 DOI: 10.1038/Sj.Onc.1209214 |
0.341 |
|
| 2005 |
Fuchs SY. De-regulation of ubiquitin-dependent proteolysis and the pathogenesis of malignant melanoma. Cancer Metastasis Reviews. 24: 329-38. PMID 15986141 DOI: 10.1007/s10555-005-1581-0 |
0.321 |
|
| 2004 |
Kumar KG, Krolewski JJ, Fuchs SY. Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor. The Journal of Biological Chemistry. 279: 46614-20. PMID 15337770 DOI: 10.1074/Jbc.M407082200 |
0.391 |
|
| 2004 |
Li Y, Kumar KG, Tang W, Spiegelman VS, Fuchs SY. Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase. Molecular and Cellular Biology. 24: 4038-48. PMID 15082796 DOI: 10.1128/MCB.24.9.4038-4048.2004 |
0.363 |
|
| 2004 |
Li Y, Gazdoiu S, Pan ZQ, Fuchs SY. Stability of homologue of Slimb F-box protein is regulated by availability of its substrate. The Journal of Biological Chemistry. 279: 11074-80. PMID 14707120 DOI: 10.1074/Jbc.M312301200 |
0.315 |
|
| 2003 |
Kumar KG, Tang W, Ravindranath AK, Clark WA, Croze E, Fuchs SY. SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor. The Embo Journal. 22: 5480-90. PMID 14532120 DOI: 10.1093/emboj/cdg524 |
0.484 |
|
| 2002 |
Fuchs SY. The role of ubiquitin-proteasome pathway in oncogenic signaling. Cancer Biology & Therapy. 1: 337-41. PMID 12432242 DOI: 10.4161/Cbt.1.4.6113 |
0.348 |
|
| 2002 |
Spiegelman VS, Tang W, Chan AM, Igarashi M, Aaronson SA, Sassoon DA, Katoh M, Slaga TJ, Fuchs SY. Induction of homologue of Slimb ubiquitin ligase receptor by mitogen signaling. The Journal of Biological Chemistry. 277: 36624-30. PMID 12151397 DOI: 10.1074/Jbc.M204524200 |
0.355 |
|
| 2001 |
Zenke G, Strittmatter U, Fuchs S, Quesniaux VF, Brinkmann V, Schuler W, Zurini M, Enz A, Billich A, Sanglier JJ, Fehr T. Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action. Journal of Immunology (Baltimore, Md. : 1950). 166: 7165-71. PMID 11390463 DOI: 10.4049/Jimmunol.166.12.7165 |
0.322 |
|
| 2000 |
Fuchs SY, Tappin I, Ronai Z. Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation. The Journal of Biological Chemistry. 275: 12560-4. PMID 10777545 DOI: 10.1074/Jbc.275.17.12560 |
0.361 |
|
| 1999 |
Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, Ronai Z. Regulation of JNK signaling by GSTp. The Embo Journal. 18: 1321-34. PMID 10064598 DOI: 10.1093/Emboj/18.5.1321 |
0.335 |
|
| 1998 |
Fuchs SY, Fried VA, Ronai Z. Stress-activated kinases regulate protein stability. Oncogene. 17: 1483-90. PMID 9779995 DOI: 10.1038/Sj.Onc.1202184 |
0.365 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2004 |
Chen ZJ, Fuchs SY. Ubiquitin-dependent activation of NF-kappaB: K63-linked ubiquitin chains: a link to cancer? Cancer Biology & Therapy. 3: 286-8. PMID 15004521 DOI: 10.4161/cbt.3.3.798 |
0.291 |
|
| 1990 |
Adorini L, Ullrich SJ, Appella E, Fuchs S. Inhibition by brefeldin A of presentation of exogenous protein antigens to MHC class II-restricted T cells. Nature. 346: 63-66. PMID 2366863 DOI: 10.1038/346063A0 |
0.29 |
|
| 1997 |
Fuchs SY, Xie B, Adler V, Fried VA, Davis RJ, Ronai Z. C-jun NH2-terminal kinases target the ubiquitination of their associated transcription factors Journal of Biological Chemistry. 272: 32163-32168. PMID 9405416 DOI: 10.1074/Jbc.272.51.32163 |
0.289 |
|
| 2016 |
Katlinskaya YV, Katlinski KV, Lasri A, Li N, Beiting DP, Durham AC, Yang T, Pikarsky E, Lengner CJ, Johnson FB, Ben-Neriah Y, Fuchs SY. Type 1 interferons control proliferation and function of intestinal epithelium. Molecular and Cellular Biology. PMID 26811327 DOI: 10.1128/MCB.00988-15 |
0.286 |
|
| 2014 |
Sato T, Tran TH, Peck AR, Girondo MA, Liu C, Goodman CR, Neilson LM, Freydin B, Chervoneva I, Hyslop T, Kovatich AJ, Hooke JA, Shriver CD, Fuchs SY, Rui H. Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression. Oncogene. 33: 2215-24. PMID 23708665 DOI: 10.1038/Onc.2013.172 |
0.284 |
|
| 1999 |
Fuchs SY, Ronai Z. Ubiquitination and degradation of ATF2 are dimerization dependent. Molecular and Cellular Biology. 19: 3289-98. PMID 10207054 DOI: 10.1128/Mcb.19.5.3289 |
0.281 |
|
| 2019 |
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, ... Fuchs SY, et al. ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature Cell Biology. 21: 889-899. PMID 31263264 DOI: 10.1038/S41556-019-0347-9 |
0.28 |
|
| 2002 |
Bhatia N, Herter JR, Slaga TJ, Fuchs SY, Spiegelman VS. Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB. Oncogene. 21: 1501-9. PMID 11896578 DOI: 10.1038/sj.onc.1205311 |
0.279 |
|
| 2018 |
Kumar S, Srivastav RK, Wilkes DW, Ross T, Kim S, Kowalski J, Chatla S, Zhang Q, Nayak A, Guha M, Fuchs SY, Thomas C, Chakrabarti R. Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer. Oncogene. PMID 30442981 DOI: 10.1038/S41388-018-0562-Z |
0.279 |
|
| 2015 |
Xia C, Vijayan M, Pritzl CJ, Fuchs SY, McDermott AB, Hahm B. Hemagglutinin of influenza A virus antagonizes type I IFN responses by inducing degradation of type I IFN receptor 1. Journal of Virology. PMID 26676772 DOI: 10.1128/JVI.02749-15 |
0.277 |
|
| 2014 |
Thom CS, Traxler EA, Khandros E, Nickas JM, Zhou OY, Lazarus JE, Silva AP, Prabhu D, Yao Y, Aribeana C, Fuchs SY, Mackay JP, Holzbaur EL, Weiss MJ. Trim58 degrades Dynein and regulates terminal erythropoiesis. Developmental Cell. 30: 688-700. PMID 25241935 DOI: 10.1016/J.Devcel.2014.07.021 |
0.276 |
|
| 2003 |
Tang W, Pavlish OA, Spiegelman VS, Parkhitko AA, Fuchs SY. Interaction of Epstein-Barr virus latent membrane protein 1 with SCFHOS/beta-TrCP E3 ubiquitin ligase regulates extent of NF-kappaB activation. The Journal of Biological Chemistry. 278: 48942-9. PMID 14523018 DOI: 10.1074/jbc.M307962200 |
0.275 |
|
| 1991 |
Adorini L, Moreno J, Momburg F, Hämmerling GJ, Guéry JC, Valli A, Fuchs S. Exogenous peptides compete for the presentation of endogenous antigens to major histocompatibility complex class II-restricted T cells. Journal of Experimental Medicine. 174: 945-948. PMID 1919443 DOI: 10.1084/Jem.174.4.945 |
0.275 |
|
| 2002 |
Fuchs SY. The Role of the Ubiquitin-Proteasome Pathway in Oncogenic Cancer Biology & Therapy. 1: 336-340. DOI: 10.4161/cbt.1.4.2 |
0.271 |
|
| 2007 |
Liu J, Suresh Kumar KG, Yu D, Molton SA, McMahon M, Herlyn M, Thomas-Tikhonenko A, Fuchs SY. Oncogenic BRAF regulates β-Trcp expression and NF-κB activity in human melanoma cells Oncogene. 26: 1954-1958. PMID 17001349 DOI: 10.1038/Sj.Onc.1209994 |
0.27 |
|
| 2001 |
Spiegelman VS, Stavropoulos P, Latres E, Pagano M, Ronai Z, Slaga TJ, Fuchs SY. Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB Journal of Biological Chemistry. 276: 27152-27158. PMID 11375388 DOI: 10.1074/Jbc.M100031200 |
0.27 |
|
| 2005 |
Fuchs SY. Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor. Cancer Biology & Therapy. 4: 506-8. PMID 15908780 DOI: 10.4161/cbt.4.5.1703 |
0.269 |
|
| 1999 |
Fuchs SY, Chen A, Xiong Y, Pan ZQ, Ronai Z. HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. Oncogene. 18: 2039-46. PMID 10321728 DOI: 10.1038/Sj.Onc.1202760 |
0.268 |
|
| 2000 |
Wu K, Fuchs SY, Chen A, Tan P, Gomez C, Ronai Z, Pan ZQ. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation. Molecular and Cellular Biology. 20: 1382-93. PMID 10648623 DOI: 10.1128/Mcb.20.4.1382-1393.2000 |
0.265 |
|
| 2008 |
HuangFu WC, Liu J, Harty RN, Fuchs SY. Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor. Febs Letters. 582: 3206-10. PMID 18722370 DOI: 10.1016/J.Febslet.2008.08.013 |
0.257 |
|
| 2022 |
Zhang H, Tomar VS, Li J, Basavaraja R, Yan F, Gui J, McBrearty N, Costich TL, Beiting DP, Blanco MA, Nefedova Y, Conejo-Garcia JR, Saggu G, Berger AJ, Gabrilovich DI, ... Fuchs SY, et al. Protection of regulatory T cells from fragility and inactivation in the tumor microenvironment. Cancer Immunology Research. PMID 36255418 DOI: 10.1158/2326-6066.CIR-22-0295 |
0.256 |
|
| 2000 |
Chen A, Wu K, Fuchs SY, Tan P, Gomez C, Pan ZQ. The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation. The Journal of Biological Chemistry. 275: 15432-9. PMID 10748083 DOI: 10.1074/Jbc.M907300199 |
0.254 |
|
| 2006 |
Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, Rustgi A, Fuchs SY, Diehl JA. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex. Molecular Cell. 24: 355-66. PMID 17081987 DOI: 10.1016/J.Molcel.2006.09.007 |
0.251 |
|
| 2001 |
Buschmann T, Potapova O, Bar-Shira A, Ivanov VN, Fuchs SY, Henderson S, Fried VA, Minamoto T, Alarcon-Vargas D, Pincus MR, Gaarde WA, Holbrook NJ, Shiloh Y, Ronai Z. Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. Molecular and Cellular Biology. 21: 2743-54. PMID 11283254 DOI: 10.1128/MCB.21.8.2743-2754.2001 |
0.249 |
|
| 1999 |
Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z, Pan ZQ. Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. Molecular Cell. 3: 527-33. PMID 10230406 DOI: 10.1016/S1097-2765(00)80481-5 |
0.248 |
|
| 2011 |
Diehl JA, Fuchs SY, Koumenis C. The cell biology of the unfolded protein response. Gastroenterology. 141: 38-41, 41.e1-2. PMID 21620842 DOI: 10.1053/j.gastro.2011.05.018 |
0.248 |
|
| 2020 |
Cho C, Mukherjee R, Peck AR, Sun Y, McBrearty N, Katlinski KV, Gui J, Govindaraju PK, Puré E, Rui H, Fuchs SY. Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis. Oncogene. PMID 32807917 DOI: 10.1038/S41388-020-01424-7 |
0.246 |
|
| 2002 |
Spiegelman VS, Tang W, Katoh M, Slaga TJ, Fuchs SY. Inhibition of HOS expression and activities by Wnt pathway. Oncogene. 21: 856-60. PMID 11850814 DOI: 10.1038/sj.onc.1205132 |
0.244 |
|
| 2015 |
Dey S, Sayers CM, Lehman SL, Cheng Y, Cerniglia GJ, Tuttle SW, Feldman MD, Zhang PJL, Fuchs SY, Diehl JA, Koumenis C. Abstract 1262: The transcription factor ATF4 regulates resistance to anoikis and promotes metastasis in fibrosarcoma via cooperative upregulation of Heme Oxygenase-1 with Nrf2 Cancer Research. 75: 1262-1262. DOI: 10.1158/1538-7445.Am2015-1262 |
0.243 |
|
| 2008 |
HuangFu W, Liu J, Harty RN, Fuchs SY. 370 Cigarette smoke products suppress anti-viral effects of Type I interferon via phosphorylation-dependent down-regulation of its receptor Cytokine. 43: 331-331. DOI: 10.1016/J.Cyto.2008.07.455 |
0.243 |
|
| 2002 |
Herter JR, Fuchs SY. Recognition of substrate and Skp1 by the Homologue of Slimb (HOS) ubiquitin ligase receptor D role of the F-box. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 8: BR283-8. PMID 12165731 |
0.241 |
|
| 2011 |
Koumenis C, Zhang H, Bi M, Lehman SL, Datta T, Liu H, Thomas-Tikhonenko A, Koong A, Fuchs SY, Diehl JA, Ruggero D. Abstract SY06-02: Activation of the UPR by c-Myc promotes transformation and tumorigenesis via cytoprotective autophagy Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy06-02 |
0.239 |
|
| 2020 |
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski KV, Alicea-Torres K, Li J, Todd L, Zhang H, Beiting DP, Sander C, Kirkwood JM, Snow BE, Wakeham AC, Mak TW, ... ... Fuchs SY, et al. Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs. Nature Cancer. 1: 603-619. PMID 34124690 DOI: 10.1038/s43018-020-0064-0 |
0.237 |
|
| 2022 |
Mucha B, Qie S, Bajpai S, Tarallo V, Diehl JN, Tedeschi F, Zhou G, Gao Z, Flashner S, Klein-Szanto AJ, Hibshoosh H, Masataka S, Chajewski OS, Majsterek I, Pytel D, ... ... Fuchs SY, et al. Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nature Communications. 13: 6614. PMID 36329064 DOI: 10.1038/s41467-022-34402-6 |
0.235 |
|
| 2004 |
Fuchs SY, Spiegelman VS, Kumar KG. The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer. Oncogene. 23: 2028-36. PMID 15021890 DOI: 10.1038/sj.onc.1207389 |
0.234 |
|
| 2005 |
Tang W, Li Y, Yu D, Thomas-Tikhonenko A, Spiegelman VS, Fuchs SY. Targeting beta-transducin repeat-containing protein E3 ubiquitin ligase augments the effects of antitumor drugs on breast cancer cells. Cancer Research. 65: 1904-8. PMID 15753389 DOI: 10.1158/0008-5472.Can-04-2597 |
0.233 |
|
| 2015 |
Yu Q, Zhao B, Gui J, Katlinski KV, Brice A, Gao Y, Li C, Kushner JA, Koumenis C, Diehl JA, Fuchs SY. Type I interferons mediate pancreatic toxicities of PERK inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 26627716 DOI: 10.1073/Pnas.1516362112 |
0.233 |
|
| 2014 |
Bhattacharya S, Katlinski KV, Reichert M, Takano S, Brice A, Zhao B, Yu Q, Zheng H, Carbone CJ, Katlinskaya YV, Leu NA, McCorkell KA, Srinivasan S, Girondo M, Rui H, ... ... Fuchs SY, et al. Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury. Embo Molecular Medicine. 6: 384-97. PMID 24480543 DOI: 10.1002/Emmm.201303236 |
0.233 |
|
| 2005 |
Fuchs SY, Ougolkov AV, Spiegelman VS, Minamoto T. Oncogenic beta-catenin signaling networks in colorectal cancer. Cell Cycle (Georgetown, Tex.). 4: 1522-39. PMID 16258275 DOI: 10.4161/cc.4.11.2129 |
0.232 |
|
| 2013 |
Katlinski KV, Bhattacharya S, Fuchs SY. 139: Tumors selectively eliminate cancer cells incapable of downregulating type I interferon receptor Cytokine. 63: 275. DOI: 10.1016/J.Cyto.2013.06.142 |
0.232 |
|
| 2016 |
Gui J, Gober M, Yang X, Katlinski KV, Marshall CM, Sharma M, Werth VP, Baker DP, Rui H, Seykora JT, Fuchs SY. Therapeutic elimination of the type 1 interferon receptor for treating psoriatic skin inflammation. The Journal of Investigative Dermatology. PMID 27369778 DOI: 10.1016/J.Jid.2016.06.608 |
0.23 |
|
| 2015 |
Yu Q, Carbone CJ, Katlinskaya YV, Zheng H, Zheng K, Luo M, Wang PJ, Greenberg RA, Fuchs SY. Type I interferon controls propagation of long interspersed element-1. The Journal of Biological Chemistry. 290: 10191-9. PMID 25716322 DOI: 10.1074/jbc.M114.612374 |
0.229 |
|
| 2016 |
Ortiz A, Fuchs SY. Anti-metastatic functions of type 1 interferons: Foundation for the adjuvant therapy of cancer. Cytokine. PMID 26822709 DOI: 10.1016/j.cyto.2016.01.010 |
0.226 |
|
| 2016 |
Chowdhury AR, Long A, Fuchs SY, Rustgi A, Avadhani NG. Mitochondrial stress-induced p53 attenuates HIF-1α activity by physical association and enhanced ubiquitination. Oncogene. PMID 27345397 DOI: 10.1038/Onc.2016.211 |
0.224 |
|
| 2017 |
Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nature Cell Biology. PMID 29230015 DOI: 10.1038/S41556-017-0006-Y |
0.22 |
|
| 2006 |
Liu J, Fuchs SY. Cross-talk between APC/C and CBP/p300. Cancer Biology & Therapy. 5: 760-2. PMID 16861917 DOI: 10.4161/cbt.5.7.3103 |
0.22 |
|
| 2021 |
Singh S, Kumar S, Srivastava RK, Nandi A, Thacker G, Murali H, Kim S, Baldeon M, Tobias J, Blanco MA, Saffie R, Zaidi MR, Sinha S, Busino L, Fuchs SY, et al. Author Correction: Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling. Nature Cell Biology. PMID 34349253 DOI: 10.1038/s41556-021-00733-7 |
0.219 |
|
| 2015 |
Yu Q, Katlinskaya YV, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N, Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY. DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function. Cell Reports. 11: 785-97. PMID 25921537 DOI: 10.1016/J.Celrep.2015.03.069 |
0.219 |
|
| 2011 |
Fuchs SY. PS1-017. Eliminative signaling by Type 1 interferons Cytokine. 56: 21. DOI: 10.1016/J.CYTO.2011.07.036 |
0.217 |
|
| 2016 |
Pytel D, Gao Y, Mackiewicz K, Katlinskaya YV, Staschke KA, Paredes MC, Yoshida A, Qie S, Zhang G, Chajewski OS, Wu L, Majsterek I, Herlyn M, Fuchs SY, Diehl JA. PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma. Plos Genetics. 12: e1006518. PMID 27977682 DOI: 10.1371/Journal.Pgen.1006518 |
0.217 |
|
| 1997 |
Adler V, Pincus MR, Minamoto T, Fuchs SY, Bluth MJ, Brandt-Rauf PW, Friedman FK, Robinson RC, Chen JM, Wang XW, Harris CC, Ronai Z. Conformation-dependent phosphorylation of p53. Proceedings of the National Academy of Sciences of the United States of America. 94: 1686-91. PMID 9050839 DOI: 10.1073/Pnas.94.5.1686 |
0.216 |
|
| 2000 |
Spiegelman VS, Slaga TJ, Pagano M, Minamoto T, Ronai Z, Fuchs SY. Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Molecular Cell. 5: 877-82. PMID 10882123 DOI: 10.1016/S1097-2765(00)80327-5 |
0.215 |
|
| 2012 |
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, ... ... Fuchs SY, et al. ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. The Journal of Clinical Investigation. 122: 4621-34. PMID 23143306 DOI: 10.1172/Jci62973 |
0.214 |
|
| 1998 |
Fuchs SY, Adler V, Pincus MR, Ronai Z. MEKK1/JNK signaling stabilizes and activates p53. Proceedings of the National Academy of Sciences of the United States of America. 95: 10541-6. PMID 9724739 DOI: 10.1073/Pnas.95.18.10541 |
0.213 |
|
| 2019 |
Ortiz A, Gui J, Zahedi F, Yu P, Cho C, Bhattacharya S, Carbone CJ, Yu Q, Katlinski KV, Katlinskaya YV, Handa S, Haas V, Volk SW, Brice AK, Wals K, ... ... Fuchs SY, et al. An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles. Cancer Cell. 35: 33-45.e6. PMID 30645975 DOI: 10.1016/J.Ccell.2018.12.001 |
0.21 |
|
| 2014 |
Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S. HCV infection selectively impairs type I but not type III IFN signaling. The American Journal of Pathology. 184: 214-29. PMID 24215913 DOI: 10.1016/J.Ajpath.2013.10.005 |
0.21 |
|
| 2017 |
Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, ... ... Fuchs SY, et al. Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment. Cancer Cell. 31: 194-207. PMID 28196594 DOI: 10.1016/J.Ccell.2017.01.004 |
0.21 |
|
| 2006 |
Noubissi FK, Elcheva I, Bhatia N, Shakoori A, Ougolkov A, Liu J, Minamoto T, Ross J, Fuchs SY, Spiegelman VS. CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. Nature. 441: 898-901. PMID 16778892 DOI: 10.1038/nature04839 |
0.21 |
|
| 2022 |
Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, ... ... Fuchs SY, et al. Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors. Nature Cancer. PMID 35637402 DOI: 10.1038/s43018-022-00383-0 |
0.208 |
|
| 2004 |
Ougolkov A, Zhang B, Yamashita K, Bilim V, Mai M, Fuchs SY, Minamoto T. Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappaB in colorectal cancer. Journal of the National Cancer Institute. 96: 1161-70. PMID 15292388 DOI: 10.1093/jnci/djh219 |
0.205 |
|
| 1998 |
Nankova BB, Fuchs SY, Serova LI, Ronai Z, Wld D, Sabban EL. Selective in vivo stimulation of stress-activated protein kinase in different rat tissues by immobilization stress Stress. 2: 289-298. PMID 9876260 DOI: 10.3109/10253899809167293 |
0.204 |
|
| 2024 |
Yang F, Akhtar MN, Zhang D, El-Mayta R, Shin J, Dorsey JF, Zhang L, Xu X, Guo W, Bagley SJ, Fuchs SY, Koumenis C, Lathia JD, Mitchell MJ, Gong Y, et al. An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science Advances. 10: eadj4678. PMID 38416830 DOI: 10.1126/sciadv.adj4678 |
0.199 |
|
| 2022 |
Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, ... ... Fuchs SY, et al. A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Nature Cell Biology. PMID 35654839 DOI: 10.1038/s41556-022-00918-8 |
0.197 |
|
| 2022 |
Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ. SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Research. PMID 35489071 DOI: 10.1093/nar/gkac304 |
0.193 |
|
| 2022 |
Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, ... Fuchs SY, et al. ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes. Cell Metabolism. 34: 1342-1358.e7. PMID 36070682 DOI: 10.1016/j.cmet.2022.08.007 |
0.189 |
|
| 2019 |
Bradley KC, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, Fuchs SY, Staeheli P, Wack A. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Reports. 28: 245-256.e4. PMID 31269444 DOI: 10.1016/j.celrep.2019.05.105 |
0.186 |
|
| 2020 |
Guo R, Xu Y, Leu NA, Zhang L, Fuchs SY, Ye L, Wang PJ. The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination. Nucleic Acids Research. PMID 33166385 DOI: 10.1093/nar/gkaa1016 |
0.177 |
|
| 2015 |
Dey S, Sayers CM, Verginadis II, Lehman SL, Cheng Y, Cerniglia GJ, Tuttle SW, Feldman MD, Zhang PJ, Fuchs SY, Diehl JA, Koumenis C. ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. The Journal of Clinical Investigation. 125: 2592-608. PMID 26011642 DOI: 10.1172/Jci78031 |
0.176 |
|
| 1999 |
Krasilnikov M, Adler V, Fuchs SY, Dong Z, Haimovitz-Friedman A, Herlyn M, Ronai Z. Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells Molecular Carcinogenesis. 24: 64-69. PMID 10029412 DOI: 10.1002/(Sici)1098-2744(199901)24:1<64::Aid-Mc9>3.0.Co;2-2 |
0.176 |
|
| 1998 |
Ronai Z, Yang YM, Fuchs SY, Adler V, Sardana M, Herlyn M. ATF2 confers radiation resistance to human melanoma cells Oncogene. 16: 523-531. PMID 9484842 DOI: 10.1038/Sj.Onc.1201566 |
0.176 |
|
| 2000 |
Buschmann T, Fuchs SY, Lee CG, Pan ZQ, Ronai Z. SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. Cell. 101: 753-62. PMID 10892746 DOI: 10.1016/S0092-8674(00)80887-9 |
0.174 |
|
| 2020 |
Ardanuy J, Scanlon K, Skerry C, Fuchs SY, Carbonetti NH. Age-Dependent Effects of Type I and Type III IFNs in the Pathogenesis of Infection and Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 32152071 DOI: 10.4049/Jimmunol.1900912 |
0.174 |
|
| 2024 |
Hardaker EL, Sanseviero E, Karmokar A, Taylor D, Milo M, Michaloglou C, Hughes A, Mai M, King M, Solanki A, Magiera L, Miragaia R, Kar G, Standifer N, Surace M, ... ... Fuchs SY, et al. The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment. Nature Communications. 15: 1700. PMID 38402224 DOI: 10.1038/s41467-024-45996-4 |
0.174 |
|
| 2005 |
Koch A, Waha A, Hartmann W, Hrychyk A, Schüller U, Waha A, Wharton KA, Fuchs SY, von Schweinitz D, Pietsch T. Elevated expression of Wnt antagonists is a common event in hepatoblastomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4295-304. PMID 15958610 DOI: 10.1158/1078-0432.CCR-04-1162 |
0.173 |
|
| 2020 |
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski KV, Alicea-Torres K, Li J, Todd L, Zhang H, Beiting DP, Sander C, Kirkwood JM, Snow BE, Wakeham AC, Mak TW, ... ... Fuchs SY, et al. Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs Nature Cancer. 1: 603-619. DOI: 10.1038/s43018-020-0064-0 |
0.171 |
|
| 2022 |
McBrearty N, Cho C, Chen J, Zahedi F, Peck AR, Radaelli E, Assenmacher CA, Pavlak C, Devine A, Yu P, Lu Z, Zhang H, Li J, Pitarresi JR, Astsaturov I, ... ... Fuchs SY, et al. Tumor suppressive and immune-stimulating roles of cholesterol 25-hydroxylase in pancreatic cancer cells. Molecular Cancer Research : McR. PMID 36378658 DOI: 10.1158/1541-7786.MCR-22-0602 |
0.167 |
|
| 2023 |
Ogier C, Solomon AMC, Lu Z, Recoules L, Klochkova A, Gabitova-Cornell L, Bayarmagnai B, Restifo D, Surumbayeva A, Vendramini-Costa DB, Deneka AY, Francescone R, Lilly AC, Sipman A, Gardiner JC, ... ... Fuchs SY, et al. Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6). Biorxiv : the Preprint Server For Biology. PMID 37745612 DOI: 10.1101/2023.09.15.557802 |
0.164 |
|
| 1995 |
Rutberg SE, Fuchs SY, Ronai Z. Ultraviolet irradiation and c-jun over-expression regulates replication of polyoma sequences in WOP cells through a PEBP2 binding site. Biochimica Et Biophysica Acta. 1261: 90-98. PMID 7893765 DOI: 10.1016/0167-4781(94)00230-Z |
0.163 |
|
| 2021 |
Sun Y, Yang N, Utama FE, Udhane SS, Zhang J, Peck AR, Yanac A, Duffey K, Langenheim JF, Udhane V, Xia G, Peterson JF, Jorns JM, Nevalainen MT, Rouet R, ... ... Fuchs SY, et al. NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers. Science Advances. 7: eabc8145. PMID 34524841 DOI: 10.1126/sciadv.abc8145 |
0.157 |
|
| 2021 |
Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, ... ... Fuchs SY, et al. Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies. The Journal of Clinical Investigation. 131. PMID 33998600 DOI: 10.1172/JCI144225 |
0.154 |
|
| 2019 |
Angireddy R, Kazmi HR, Srinivasan S, Sun L, Iqbal J, Fuchs SY, Guha M, Kijima T, Yuen T, Zaidi M, Avadhani NG. Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900010RR. PMID 31063702 DOI: 10.1096/Fj.201900010Rr |
0.152 |
|
| 2000 |
Alarcon-Vargas D, Fuchs SY, Deb S, Ronai Z. p73 transcriptional activity increases upon cooperation between its spliced forms. Oncogene. 19: 831-5. PMID 10698502 DOI: 10.1038/Sj.Onc.1203311 |
0.151 |
|
| 2023 |
Zhang D, Li AM, Hu G, Huang M, Yang F, Zhang L, Wellen KE, Xu X, Conn CS, Zou W, Kahn M, Rhoades SD, Weljie AM, Fuchs SY, Amankulor N, et al. PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy. Cell Metabolism. PMID 36804058 DOI: 10.1016/j.cmet.2023.01.010 |
0.15 |
|
| 1997 |
Spiegelman VS, Fuchs SY, Belitsky GA. The expression of insecticide resistance-related cytochrome P450 forms is regulated by molting hormone in Drosophila melanogaster. Biochemical and Biophysical Research Communications. 232: 304-7. PMID 9125169 DOI: 10.1006/BBRC.1997.6273 |
0.146 |
|
| 1998 |
Fuchs SY, Adler V, Buschmann T, Yin Z, Wu X, Jones SN, Ronai Z. JNK targets p53 ubiquitination and degradation in nonstressed cells Genes and Development. 12: 2658-2663. PMID 9732264 DOI: 10.1101/Gad.12.17.2658 |
0.145 |
|
| 2001 |
Buschmann T, Lin Y, Aithmitti N, Fuchs SY, Lu H, Resnick-Silverman L, Manfredi JJ, Ronai Z, Wu X. Stabilization and activation of p53 by the coactivator protein TAFII31. The Journal of Biological Chemistry. 276: 13852-7. PMID 11278372 DOI: 10.1074/Jbc.M007955200 |
0.144 |
|
| 2022 |
Lu Z, Chen J, Yu P, Atherton MJ, Gui J, Tomar VS, Middleton JD, Sullivan NT, Singhal S, George SS, Woolfork AG, Weljie AM, Hai T, Eruslanov EB, Fuchs SY. Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer. Nature Communications. 13: 6623. PMID 36333297 DOI: 10.1038/s41467-022-34428-w |
0.143 |
|
| 1998 |
Fuchs SY, Adler V, Buschmann T, Wu X, Ronai Z. Mdm2 association with p53 targets its ubiquitination Oncogene. 17: 2543-2547. PMID 9824166 DOI: 10.1038/Sj.Onc.1202200 |
0.142 |
|
| 2012 |
Chitnis NS, Pytel D, Bobrovnikova-Marjon E, Pant D, Zheng H, Maas NL, Frederick B, Kushner JA, Chodosh LA, Koumenis C, Fuchs SY, Diehl JA. miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Molecular Cell. 48: 353-64. PMID 23022383 DOI: 10.1016/J.Molcel.2012.08.025 |
0.142 |
|
| 2022 |
Lu Z, Bae EA, Verginadis II, Zhang H, Cho C, McBrearty N, George SS, Diehl JA, Koumenis C, Bradley LM, Fuchs SY. Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities. Cancer Immunology, Immunotherapy : Cii. PMID 36063172 DOI: 10.1007/s00262-022-03286-2 |
0.139 |
|
| 2016 |
Xu Z, Bu Y, Chitnis N, Koumenis C, Fuchs SY, Diehl JA. miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis. Nature Communications. 7: 11422. PMID 27173017 DOI: 10.1038/ncomms11422 |
0.138 |
|
| 2004 |
Pak BJ, Lee J, Thai BL, Fuchs SY, Shaked Y, Ronai Z, Kerbel RS, Ben-David Y. Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase. Oncogene. 23: 30-8. PMID 14712208 DOI: 10.1038/Sj.Onc.1207007 |
0.137 |
|
| 2000 |
Buschmann T, Minamoto T, Wagle N, Fuchs SY, Adler V, Mai M, Ronai Z. Analysis of JNK, Mdm2 and p14(ARF) contribution to the regulation of mutant p53 stability. Journal of Molecular Biology. 295: 1009-21. PMID 10656807 DOI: 10.1006/Jmbi.1999.3387 |
0.137 |
|
| 2011 |
Fuchs SY. A DUB for MITF: no myth, some dubiety. Pigment Cell & Melanoma Research. 24: 877-8. PMID 22081812 DOI: 10.1111/j.1755-148X.2011.00900.x |
0.136 |
|
| 2016 |
Zhang K, Yin XF, Yang YQ, Li HL, Xu YN, Chen LY, Liu XJ, Yuan SJ, Fang XL, Xiao J, Wu S, Xu H, Chu L, Katlinski KV, Katlinskaya YV, ... ... Fuchs SY, et al. A potent in vivo anti-tumor efficacy of novel recombinant type I interferon. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27683179 DOI: 10.1158/1078-0432.CCR-16-1386 |
0.132 |
|
| 2008 |
Fuchs SY. MYC-induced sensitivity of human malignant melanoma to proteasome inhibitors - a KaMYCaze effect. Pigment Cell & Melanoma Research. 21: 9-10. PMID 18353138 DOI: 10.1111/j.1755-148X.2007.00438.x |
0.132 |
|
| 2023 |
Guo W, Zhong W, Xiao Z, Qin Z, Yang J, Wen Y, Yu Z, Li Y, Sheppard NC, Fuchs SY, Xu X, Herlyn M, June CH, Pure E. Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer Research. PMID 37115855 DOI: 10.1158/0008-5472.CAN-22-2220 |
0.125 |
|
| 2018 |
Ghosh J, Roy Chowdhury A, Srinivasan S, Chattopadhyay M, Bose M, Bhattacharya S, Raza H, Fuchs SY, Rustgi AK, Gonzalez FJ, Avadhani NG. Cigarette Smoke Toxins-induced mitochondrial dysfunction and pancreatitis involves Aryl hydrocarbon receptor mediated Cyp1 gene expression: protective effects of resveratrol. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30165701 DOI: 10.1093/Toxsci/Kfy206 |
0.121 |
|
| 2024 |
Dey N, Koumenis C, Ruggero D, Fuchs SY, Diehl JA. miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress. Molecular Cancer Research : McR. PMID 38236939 DOI: 10.1158/1541-7786.MCR-23-0676 |
0.12 |
|
| 2023 |
Chervoneva I, Peck AR, Sun Y, Yi M, Udhane SS, Langenheim JF, Girondo MA, Jorns JM, Chaudhary LN, Kamaraju S, Bergom C, Flister MJ, Hooke JA, Kovatich AJ, Shriver CD, ... ... Fuchs SY, et al. High PD-L2 Predicts Early Recurrence of ER-Positive Breast Cancer. Jco Precision Oncology. 7: e2100498. PMID 36652667 DOI: 10.1200/PO.21.00498 |
0.119 |
|
| 1996 |
Fuchs SY, Ronai Z. Elevated binding to URE/PEBP2 during the late stages of NNK and benzo[a]pyrene-induced carcinogenesis in A/J mice. Cancer Letters. 102: 101-6. PMID 8603357 DOI: 10.1016/0304-3835(96)04165-1 |
0.118 |
|
| 2019 |
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salinas CS, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, ... Fuchs SY, et al. Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature Cell Biology. PMID 31316187 DOI: 10.1038/S41556-019-0370-X |
0.108 |
|
| 2002 |
Fuchs SY, Lee CG, Pan ZQ, Ronai Z. SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. Cell. 110: 531. PMID 12202042 |
0.105 |
|
| 1994 |
Fuchs SY, Spiegelman VS, Belitsky GA. Inducibility of various cytochrome P450 isozymes by phenobarbital and some other xenobiotics in Drosophila melanogaster. Biochemical Pharmacology. 47: 1867-73. PMID 8204104 DOI: 10.1016/0006-2952(94)90317-4 |
0.101 |
|
| 2010 |
Diehl JA, Fuchs SY, Haines DS. Ubiquitin and cancer: new discussions for a new journal. Genes & Cancer. 1: 679-80. PMID 21779465 DOI: 10.1177/1947601910383565 |
0.099 |
|
| 2021 |
Lightcap ES, Yu P, Grossman S, Song K, Khattar M, Xega K, He X, Gavin JM, Imaichi H, Garnsey JJ, Koenig E, Zhang H, Lu Z, Shah P, Fu Y, ... ... Fuchs SY, et al. A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models. Science Translational Medicine. 13: eaba7791. PMID 34524860 DOI: 10.1126/scitranslmed.aba7791 |
0.098 |
|
| 2016 |
Davar D, Fuchs SY, Kirkwood JM. BRAF Inhibitors and IFNα: Plus, Minus, or Indeterminate? Journal of the National Cancer Institute. 108. PMID 26851801 DOI: 10.1093/jnci/djv432 |
0.072 |
|
| 1998 |
Toussaint O, Fuchs SY, Ronai ZA, Isoyama S, Yuko N, Petronilli V, Bernardi P, Gonos ES, Dumont P, Remacle J. Reciprocal relationships between the resistance to stresses and cellular aging. Annals of the New York Academy of Sciences. 851: 450-65. PMID 9668639 DOI: 10.1111/j.1749-6632.1998.tb09023.x |
0.031 |
|
| 2015 |
Fuchs SY. ID: 110 Cytokine. 76: 86. DOI: 10.1016/J.CYTO.2015.08.137 |
0.03 |
|
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