Year |
Citation |
Score |
2018 |
Wang ZF, Ursu A, Childs-Disney JL, Guertler R, Yang WY, Bernat V, Rzuczek SG, Fuerst R, Zhang YJ, Gendron TF, Yildirim I, Dwyer BG, Rice JE, Petrucelli L, Disney MD. The Hairpin Form of r(GC) in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules. Cell Chemical Biology. PMID 30503283 DOI: 10.1016/J.Chembiol.2018.10.018 |
0.592 |
|
2016 |
Angelbello AJ, González ÀL, Rzuczek SG, Disney MD. Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1. Bioorganic & Medicinal Chemistry Letters. PMID 27839685 DOI: 10.1016/J.Bmcl.2016.10.037 |
0.3 |
|
2014 |
Tran T, Childs-Disney JL, Liu B, Guan L, Rzuczek S, Disney MD. Targeting the r(CGG) repeats that cause FXTAS with modularly assembled small molecules and oligonucleotides. Acs Chemical Biology. 9: 904-12. PMID 24506227 DOI: 10.1021/Cb400875U |
0.308 |
|
2013 |
Blankson G, Rzuczek SG, Bishop C, Pilch DS, Liu A, Liu L, Lavoie EJ, Rice JE. Macrocyclic pyridyl polyoxazoles: structure-activity studies of the aminoalkyl side-chain on G-quadruplex stabilization and cytotoxic activity. Molecules (Basel, Switzerland). 18: 11938-63. PMID 24077174 DOI: 10.3390/Molecules181011938 |
0.721 |
|
2010 |
Satyanarayana M, Kim YA, Rzuczek SG, Pilch DS, Liu AA, Liu LF, Rice JE, LaVoie EJ. Macrocyclic hexaoxazoles: Influence of aminoalkyl substituents on RNA and DNA G-quadruplex stabilization and cytotoxicity. Bioorganic & Medicinal Chemistry Letters. 20: 3150-4. PMID 20409709 DOI: 10.1016/J.Bmcl.2010.03.086 |
0.711 |
|
2010 |
Rzuczek SG, Pilch DS, Liu A, Liu L, LaVoie EJ, Rice JE. Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents. Journal of Medicinal Chemistry. 53: 3632-44. PMID 20359224 DOI: 10.1021/Jm1000612 |
0.743 |
|
2009 |
Tsai YC, Qi H, Lin CP, Lin RK, Kerrigan JE, Rzuczek SG, LaVoie EJ, Rice JE, Pilch DS, Lyu YL, Liu LF. A G-quadruplex stabilizer induces M-phase cell cycle arrest. The Journal of Biological Chemistry. 284: 22535-43. PMID 19531483 DOI: 10.1074/Jbc.M109.020230 |
0.683 |
|
2008 |
Satyanarayana M, Rzuczek SG, Lavoie EJ, Pilch DS, Liu A, Liu LF, Rice JE. Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency. Bioorganic & Medicinal Chemistry Letters. 18: 3802-4. PMID 18515097 DOI: 10.1016/J.Bmcl.2008.05.032 |
0.723 |
|
2008 |
Pilch DS, Barbieri CM, Rzuczek SG, Lavoie EJ, Rice JE. Targeting human telomeric G-quadruplex DNA with oxazole-containing macrocyclic compounds. Biochimie. 90: 1233-49. PMID 18439430 DOI: 10.1016/J.Biochi.2008.03.011 |
0.725 |
|
2008 |
Rzuczek SG, Pilch DS, LaVoie EJ, Rice JE. Lysinyl macrocyclic hexaoxazoles: synthesis and selective G-quadruplex stabilizing properties. Bioorganic & Medicinal Chemistry Letters. 18: 913-7. PMID 18248989 DOI: 10.1016/J.Bmcl.2007.12.048 |
0.717 |
|
2007 |
Barbieri CM, Srinivasan AR, Rzuczek SG, Rice JE, LaVoie EJ, Pilch DS. Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA. Nucleic Acids Research. 35: 3272-86. PMID 17452355 DOI: 10.1093/Nar/Gkm188 |
0.687 |
|
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