Witold Filipowicz - Publications

Affiliations: 
Friedrich Miescher Institute, Basel, Basel, Basel-Stadt, Switzerland 
Area:
RNA biology, gene expression, RNA viruses, small RNAs, microRNAs, RNA silencing, RNA enzymology, mRNA translation
Website:
http://www.fmi.ch/research/groupleader/?group=9

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Calviello L, Venkataramanan S, Rogowski KJ, Wyler E, Wilkins K, Tejura M, Thai B, Krol J, Filipowicz W, Landthaler M, Floor SN. DDX3 depletion represses translation of mRNAs with complex 5' UTRs. Nucleic Acids Research. 49: 5336-5350. PMID 33905506 DOI: 10.1093/nar/gkab287  0.372
2016 Filipowicz W. RNA 3'-terminal phosphate cyclases and cyclase-like proteins. Postepy Biochemii. 62: 327-334. PMID 28132487  0.354
2015 Filipowicz W, Sonenberg N. The long unfinished march towards understanding microRNA-mediated repression. Rna (New York, N.Y.). 21: 519-24. PMID 25780122 DOI: 10.1261/Rna.051219.115  0.47
2013 Doyle M, Badertscher L, Jaskiewicz L, Güttinger S, Jurado S, Hugenschmidt T, Kutay U, Filipowicz W. The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal. Rna (New York, N.Y.). 19: 1238-52. PMID 23882114 DOI: 10.1261/Rna.039255.113  0.35
2013 Loedige I, Gaidatzis D, Sack R, Meister G, Filipowicz W. The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function. Nucleic Acids Research. 41: 518-32. PMID 23125361 DOI: 10.1093/nar/gks1032  0.335
2012 Kundu P, Fabian MR, Sonenberg N, Bhattacharyya SN, Filipowicz W. HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA. Nucleic Acids Research. 40: 5088-100. PMID 22362743 DOI: 10.1093/Nar/Gks148  0.48
2012 Nejepinska J, Malik R, Filkowski J, Flemr M, Filipowicz W, Svoboda P. dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells. Nucleic Acids Research. 40: 399-413. PMID 21908396 DOI: 10.1093/Nar/Gkr702  0.343
2011 Meisner NC, Filipowicz W. Properties of the Regulatory RNA-Binding Protein HuR and its Role in Controlling miRNA Repression. Advances in Experimental Medicine and Biology. 700: 106-23. PMID 21755477 DOI: 10.1007/978-1-4419-7823-3_10  0.301
2010 Meisner NC, Filipowicz W. Properties of the regulatory RNA-binding protein HuR and its role in controlling miRNA repression. Advances in Experimental Medicine and Biology. 700: 106-23. PMID 21627034  0.314
2010 Sinkkonen L, Hugenschmidt T, Filipowicz W, Svoboda P. Dicer is associated with ribosomal DNA chromatin in mammalian cells. Plos One. 5: e12175. PMID 20730047 DOI: 10.1371/Journal.Pone.0012175  0.339
2010 Fabian MR, Sonenberg N, Filipowicz W. Regulation of mRNA translation and stability by microRNAs. Annual Review of Biochemistry. 79: 351-79. PMID 20533884 DOI: 10.1146/Annurev-Biochem-060308-103103  0.446
2010 Chekulaeva M, Parker R, Filipowicz W. The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression. Nucleic Acids Research. 38: 6673-83. PMID 20530530 DOI: 10.1093/Nar/Gkq501  0.348
2009 Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR, Hannon GJ, Filipowicz W, et al. Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Molecular Cell. 35: 868-80. PMID 19716330 DOI: 10.1016/J.Molcel.2009.08.004  0.434
2009 Zipprich JT, Bhattacharyya S, Mathys H, Filipowicz W. Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression. Rna (New York, N.Y.). 15: 781-93. PMID 19304925 DOI: 10.1261/rna.1448009  0.366
2008 Jaskiewicz L, Filipowicz W. Role of Dicer in posttranscriptional RNA silencing. Current Topics in Microbiology and Immunology. 320: 77-97. PMID 18268840 DOI: 10.1007/978-3-540-75157-1_4  0.362
2008 Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nature Reviews. Genetics. 9: 102-14. PMID 18197166 DOI: 10.1038/Nrg2290  0.482
2007 Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, Filipowicz W, Duchaine TF, Sonenberg N. MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science (New York, N.Y.). 317: 1764-7. PMID 17656684 DOI: 10.1126/Science.1146067  0.497
2007 Bhattacharyya SN, Filipowicz W. Argonautes and company: sailing against the wind. Cell. 128: 1027-8. PMID 17382873 DOI: 10.1016/j.cell.2007.02.033  0.314
2006 Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W. Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells. Cold Spring Harbor Symposia On Quantitative Biology. 71: 513-21. PMID 17381334 DOI: 10.1101/sqb.2006.71.038  0.303
2006 Schmitter D, Filkowski J, Sewer A, Pillai RS, Oakeley EJ, Zavolan M, Svoboda P, Filipowicz W. Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells. Nucleic Acids Research. 34: 4801-15. PMID 16971455 DOI: 10.1093/Nar/Gkl646  0.364
2006 Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell. 125: 1111-24. PMID 16777601 DOI: 10.1016/j.cell.2006.04.031  0.322
2005 Haase AD, Jaskiewicz L, Zhang H, Lainé S, Sack R, Gatignol A, Filipowicz W. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. Embo Reports. 6: 961-7. PMID 16142218 DOI: 10.1038/sj.embor.7400509  0.345
2005 Pillai RS, Bhattacharyya SN, Artus CG, Zoller T, Cougot N, Basyuk E, Bertrand E, Filipowicz W. Inhibition of translational initiation by Let-7 MicroRNA in human cells. Science (New York, N.Y.). 309: 1573-6. PMID 16081698 DOI: 10.1126/science.1115079  0.386
2005 Filipowicz W. RNAi: the nuts and bolts of the RISC machine. Cell. 122: 17-20. PMID 16009129 DOI: 10.1016/j.cell.2005.06.023  0.319
2005 Filipowicz W, Jaskiewicz L, Kolb FA, Pillai RS. Post-transcriptional gene silencing by siRNAs and miRNAs. Current Opinion in Structural Biology. 15: 331-41. PMID 15925505 DOI: 10.1016/j.sbi.2005.05.006  0.374
2005 Kolb FA, Zhang H, Jaronczyk K, Tahbaz N, Hobman TC, Filipowicz W. Human dicer: purification, properties, and interaction with PAZ PIWI domain proteins. Methods in Enzymology. 392: 316-36. PMID 15644190 DOI: 10.1016/S0076-6879(04)92019-8  0.301
2004 Zhang H, Kolb FA, Jaskiewicz L, Westhof E, Filipowicz W. Single processing center models for human Dicer and bacterial RNase III. Cell. 118: 57-68. PMID 15242644 DOI: 10.1016/j.cell.2004.06.017  0.341
2004 Tahbaz N, Kolb FA, Zhang H, Jaronczyk K, Filipowicz W, Hobman TC. Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer. Embo Reports. 5: 189-94. PMID 14749716 DOI: 10.1038/Sj.Embor.7400070  0.305
2002 Zhang H, Kolb FA, Brondani V, Billy E, Filipowicz W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. The Embo Journal. 21: 5875-85. PMID 12411505 DOI: 10.1093/emboj/cdf582  0.339
2002 Filipowicz W, Pogaci? V. Biogenesis of small nucleolar ribonucleoproteins. Current Opinion in Cell Biology. 14: 319-27. PMID 12067654 DOI: 10.1016/S0955-0674(02)00334-4  0.354
2002 Lambermon MH, Fu Y, Wieczorek Kirk DA, Dupasquier M, Filipowicz W, Lorkovi? ZJ. UBA1 and UBA2, two proteins that interact with UBP1, a multifunctional effector of pre-mRNA maturation in plants. Molecular and Cellular Biology. 22: 4346-57. PMID 12024044 DOI: 10.1128/MCB.22.12.4346-4357.2002  0.405
2001 Billy E, Brondani V, Zhang H, Müller U, Filipowicz W. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proceedings of the National Academy of Sciences of the United States of America. 98: 14428-33. PMID 11724966 DOI: 10.1073/pnas.261562698  0.326
2001 Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M, et al. New ways of initiating translation in eukaryotes. Molecular and Cellular Biology. 21: 8238-46. PMID 11710333 DOI: 10.1128/Mcb.21.23.8238-8246.2001  0.393
2000 Lorkovi? ZJ, Wieczorek Kirk DA, Klahre U, Hemmings-Mieszczak M, Filipowicz W. RBP45 and RBP47, two oligouridylate-specific hnRNP-like proteins interacting with poly(A)+ RNA in nuclei of plant cells. Rna (New York, N.Y.). 6: 1610-24. PMID 11105760 DOI: 10.1017/S1355838200001163  0.401
2000 Lahmy S, Barnèche F, Derancourt J, Filipowicz W, Delseny M, Echeverria M. A chloroplastic RNA-binding protein is a new member of the PPR family. Febs Letters. 480: 255-60. PMID 11034340 DOI: 10.1016/S0014-5793(00)01935-9  0.324
2000 Billy E, Wegierski T, Nasr F, Filipowicz W. Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis. The Embo Journal. 19: 2115-26. PMID 10790377 DOI: 10.1093/emboj/19.9.2115  0.372
2000 Lambermon MH, Simpson GG, Wieczorek Kirk DA, Hemmings-Mieszczak M, Klahre U, Filipowicz W. UBP1, a novel hnRNP-like protein that functions at multiple steps of higher plant nuclear pre-mRNA maturation. The Embo Journal. 19: 1638-49. PMID 10747031 DOI: 10.1093/emboj/19.7.1638  0.348
2000 Palm GJ, Billy E, Filipowicz W, Wlodawer A. Crystal structure of RNA 3'-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology. Structure (London, England : 1993). 8: 13-23. PMID 10673421 DOI: 10.1016/S0969-2126(00)00076-9  0.337
1999 Billy E, Hess D, Hofsteenge J, Filipowicz W. Characterization of the adenylation site in the RNA 3'-terminal phosphate cyclase from Escherichia coli. The Journal of Biological Chemistry. 274: 34955-60. PMID 10574971 DOI: 10.1074/jbc.274.49.34955  0.368
1999 Filipowicz W, Pelczar P, Pogacic V, Dragon F. Structure and biogenesis of small nucleolar RNAs acting as guides for ribosomal RNA modification. Acta Biochimica Polonica. 46: 377-89. PMID 10547039  0.349
1998 Filipowicz W, Billy E, Drabikowski K, Genschik P. Cyclases of the 3'-terminal phosphate in RNA: a new family of RNA processing enzymes conserved in eucarya, bacteria and archaea. Acta Biochimica Polonica. 45: 895-906. PMID 10397337  0.368
1998 Genschik P, Drabikowski K, Filipowicz W. Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon. The Journal of Biological Chemistry. 273: 25516-26. PMID 9738023 DOI: 10.1074/jbc.273.39.25516  0.363
1998 Pelczar P, Filipowicz W. The host gene for intronic U17 small nucleolar RNAs in mammals has no protein-coding potential and is a member of the 5'-terminal oligopyrimidine gene family. Molecular and Cellular Biology. 18: 4509-18. PMID 9671460  0.35
1997 Genschik P, Billy E, Swianiewicz M, Filipowicz W. The human RNA 3'-terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea. The Embo Journal. 16: 2955-67. PMID 9184239 DOI: 10.1093/emboj/16.10.2955  0.35
1996 Kiss T, Bortolin ML, Filipowicz W. Characterization of the intron-encoded U19 RNA, a new mammalian small nucleolar RNA that is not associated with fibrillarin. Molecular and Cellular Biology. 16: 1391-400. PMID 8657112  0.366
1995 Kiss T, Filipowicz W. Exonucleolytic processing of small nucleolar RNAs from pre-mRNA introns. Genes & Development. 9: 1411-24. PMID 7797080  0.366
1995 Klahre U, Hemmings-Mieszczak M, Filipowicz W. Extreme heterogeneity of polyadenylation sites in mRNAs encoding chloroplast RNA-binding proteins in Nicotiana plumbaginifolia. Plant Molecular Biology. 28: 569-74. PMID 7632924 DOI: 10.1007/BF00020402  0.367
1993 Kiss T, Filipowicz W. Small nucleolar RNAs encoded by introns of the human cell cycle regulatory gene RCC1 Embo Journal. 12: 2913-2920. PMID 8335005  0.372
1993 Heard DJ, Kiss T, Filipowicz W. Both Arabidopsis TATA binding protein (TBP) isoforms are functionally identical in RNA polymerase II and III transcription in plant cells: Evidence for gene-specific changes in DNA binding specificity of TBP Embo Journal. 12: 3519-3528. PMID 8253078  0.308
1992 Shimba S, Buckley B, Reddy R, Kiss T, Filipowicz W. Cap structure of U3 small nucleolar RNA in animal and plant cells is different. γ-Monomethyl phosphate cap structure in plant RNA Journal of Biological Chemistry. 267: 13772-13777. PMID 1618872  0.331
1992 Mieszczak M, Klahre U, Levy JH, Goodall GJ, Filipowicz W. Multiple plant RNA binding proteins identified by PCR: expression of cDNAs encoding RNA binding proteins targeted to chloroplasts in Nicotiana plumbaginifolia Mgg Molecular & General Genetics. 234: 390-400. PMID 1406585 DOI: 10.1007/BF00538698  0.358
1992 Kiss T, Marshallsay C, Filipowicz W. 7-2/MRP RNAs in plant and mammalian cells: Association with higher order structures in the nucleolus Embo Journal. 11: 3737-3746. PMID 1382978  0.356
1990 Waibel F, Filipowicz W. The spacing between two promoter elements determines RNA polymerase specificity during transcription of U small nuclear RNA genes of Arabidopsis Molecular Biology Reports. 14: 149. PMID 2362571 DOI: 10.1007/BF00360453  0.305
1990 Filipowicz W, Vicente O. RNA 3'-terminal phosphate cyclase from HeLa cells Methods in Enzymology. 181: 499-510. PMID 2199762 DOI: 10.1016/0076-6879(90)81147-M  0.34
1988 Vicente O, Filipowicz W. Purification of RNA 3'-terminal phosphate cyclase from HeLa cells. Covalent modification of the enzyme with different nucleotides European Journal of Biochemistry. 176: 431-439. PMID 3416880 DOI: 10.1111/J.1432-1033.1988.TB14300.X  0.319
1985 Filipowicz W, Strugala K, Konarska M, Shatkin AJ. Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells proceeds via formation of N(3')pp(5')A activated intermediate. Proceedings of the National Academy of Sciences of the United States of America. 82: 1316-20. PMID 2579395 DOI: 10.1073/Pnas.82.5.1316  0.559
1984 Filipowicz W, Gross HJ. RNA ligation in eukaryotes Trends in Biochemical Sciences. 9: 68-71. DOI: 10.1016/0968-0004(84)90186-5  0.323
1983 Filipowicz W, Konarska M, Gross HJ, Shatkin AJ. RNA 3'-terminal phosphate cyclase activity and RNA ligation in HeLa cell extract. Nucleic Acids Research. 11: 1405-18. PMID 6828385 DOI: 10.1093/Nar/11.5.1405  0.578
1983 Ernst H, Filipowicz W, Shatkin AJ. Initiation by RNA polymerase II and formation of runoff transcripts containing unblocked and unmethylated 5' termini. Molecular and Cellular Biology. 3: 2172-9. PMID 6361523  0.562
1983 Filipowicz W, Shatkin AJ. Origin of splice junction phosphate in tRNAs processed by HeLa cell extract. Cell. 32: 547-57. PMID 6186399 DOI: 10.1016/0092-8674(83)90474-9  0.555
1982 Konarska M, Filipowicz W, Gross HJ. RNA ligation via 2'-phosphomonoester, 3',5'-phosphodiester linkage: Requirement of 2',3'-cyclic phosphate termini and involvement of a 5'-hydroxyl polynucleotide kinase Proceedings of the National Academy of Sciences of the United States of America. 79: 1474-1478. PMID 6280184 DOI: 10.1073/Pnas.79.5.1474  0.349
1981 Konarska M, Filipowicz W, Domdey H, Gross HJ. Formation of a 2′-phosphomonoester, 3′,5′-phosphodiester linkage by a novel RNA ligase in wheat germ Nature. 293: 112-116. PMID 7266664 DOI: 10.1038/293112A0  0.348
1981 Konarska M, Filipowicz W, Domdey H, Gross HJ. Binding of ribosomes to linear and circular forms of the 5'-terminal leader fragment of tobacco-mosaic-virus RNA European Journal of Biochemistry. 114: 221-227. PMID 6783406 DOI: 10.1111/J.1432-1033.1981.Tb05139.X  0.396
1981 Szczesna-Skorupa E, Filipowicz W, Paszewski A. The cell-free protein synthesis system from the 'slime' mutant of Neurospora crassa. Preparation and characterisation of importance of 7-methylguanosine for translation of viral and cellular mRNAs European Journal of Biochemistry. 121: 163-168. PMID 6459928 DOI: 10.1111/j.1432-1033.1981.tb06445.x  0.369
1979 Filipowicz W, Haenni AL. Binding of ribosomes to 5'-terminal leader sequences of eukaryotic messenger RNAs Proceedings of the National Academy of Sciences of the United States of America. 76: 3111-3115. PMID 290990  0.383
1978 Wodnar-Filipowicz A, Szczesna E, Zan-Kowalczewska M, Muthukrishnan S, Szybiak U, Legocki AB, Filipowicz W. 5'-Terminal 7-methylguanosine and mRNA function. The effect of enzymatic decapping and of cap analogs on translation of tobacco-mosaic-virus RNA and globin mRNA in vitro European Journal of Biochemistry. 92: 69-80. PMID 729595 DOI: 10.1111/j.1432-1033.1978.tb12724.x  0.438
1978 Jozwiak W, Wodnar-Filipowicz A, Filipowicz W, Koscielak J. RNA in surface antigen of hepatitis B virus (HB(S)Ag) Acta Haematologica Polonica. 9: 125-128. PMID 665132  0.322
1978 Filipowicz W, Szczesna E, Wodmar-Filipowicz A. Role of 5'-terminal 7-methylguanosine in mRNA function: Correlation of the effect of enzymatic mRNA decapping with the effect of cap analogs on in vitro translation of TMV RNA and globin mRNA Biochimie. 60: 569.  0.364
1977 Zan-Kowalczewska M, Bretner M, Sierakowska H, Szczesna E, Filipowicz W, Shatkin AJ. Removal of 5'-terminal m7G from eukaryotic mRNAs by potato nucleotide pyrophosphatase and its effect on translation. Nucleic Acids Research. 4: 3065-81. PMID 909799 DOI: 10.1093/nar/4.9.3065  0.613
1977 Lee-Huang S, Sierra JM, Naranjo R, Filipowicz W, Ochoa S. Eucaryotic oligonucleotides affecting mRNA translation Archives of Biochemistry and Biophysics. 180: 276-287. PMID 879789 DOI: 10.1016/0003-9861(77)90039-X  0.562
1976 Sierra JM, Filipowicz W, Ochoa S. Messenger RNA in undeveloped and developing Artemia salina embryos Biochemical and Biophysical Research Communications. 69: 181-189. PMID 1259754 DOI: 10.1016/S0006-291X(76)80289-6  0.603
1976 Filipowicz W, Furuichi Y, Sierra JM, Muthukrishnan S, Shatkin AJ, Ochoa S. A protein binding the methylated 5'-terminal sequence, m7GpppN, of eukaryotic messenger RNA. Proceedings of the National Academy of Sciences of the United States of America. 73: 1559-63. PMID 1064023 DOI: 10.1073/Pnas.73.5.1559  0.643
1976 Filipowicz W, Sierra JM, Nombela C, Ochoa S, Merrick WC, Anderson WF. Polypeptide chain initiation in eukaryotes: Initiation factor requirements for translation of natural messengers Proceedings of the National Academy of Sciences of the United States of America. 73: 44-48. PMID 1061126 DOI: 10.1073/pnas.73.1.44  0.507
1976 Filipowicz W, Wodnar Filipowicz A, Szafranski P. Activity of methoxyamine modified f2 RNA in initiation and elongation steps of protein synthesis Acta Biochimica Polonica. 23: 243-259. PMID 788415  0.375
1975 Muthukrishnan S, Filipowicz W, Sierra JM, Both GW, Shatkin AJ, Ochoa S. mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia salina. The Journal of Biological Chemistry. 250: 9336-41. PMID 1194288  0.559
1975 Filipowicz W, Sierra JM, Ochoa S. Polypeptide chain initiation in eukaryotes: initiation factor MP in Artemia salina embryos Proceedings of the National Academy of Sciences of the United States of America. 72: 3947-3951. PMID 1105571 DOI: 10.1073/Pnas.72.10.3947  0.522
1972 Filipowicz W, Zagórski W. Bacterial RNA viruses. II. RNA and its translation | Wirusy bakteryjne zawierajace kwas rybonukleinowy. II. RNA i jego translacja Postepy Biochemii. 18: 593-617. PMID 4566060  0.308
Show low-probability matches.