Lorenzo Federico, Ph.D. - Publications

Affiliations: 
2011 University of Kentucky, Lexington, KY 
Area:
Cell Biology

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mitchell KG, Diao L, Karpinets T, Negrao MV, Tran HT, Parra ER, Corsini EM, Reuben A, Federico L, Bernatchez C, Dejima H, Francisco-Cruz A, Wang J, Antonoff MB, Vaporciyan AA, et al. Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort. Journal For Immunotherapy of Cancer. 8. PMID 32350118 DOI: 10.1136/Jitc-2019-000405  0.307
2019 Wang Z, Sun K, Xiao Y, Feng B, Mikule K, Ma X, Feng N, Vellano CP, Federico L, Marszalek JR, Mills GB, Hanke J, Ramaswamy S, Wang J. Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. Scientific Reports. 9: 1853. PMID 30755715 DOI: 10.1038/S41598-019-38534-6  0.319
2019 Mitchell KG, Diao L, Tran HT, Negrao MV, Karpinets T, Wang J, Parra Cuentas ER, Corsini EM, Reuben A, Federico L, Bernatchez C, Vaporciyan AA, Swisher S, Cascone T, Wistuba II, et al. Association of relative neutrophilia with a distinct immunoinhibitory milieu in non-small cell lung cancer. Journal of Clinical Oncology. 37: e14047-e14047. DOI: 10.1200/Jco.2019.37.15_Suppl.E14047  0.308
2019 Negrao MV, Karpinets T, Li J, Reuben A, Haymaker C, Mitchell KG, Fujimoto J, Chow C, Parra ER, Federico L, Zhang J, Vaporciyan AA, Bernatchez C, Cascone T, Sepesi B, et al. Abstract 1176: Immunogenomic profiling identifies a subgroup of squamous cell lung cancers with immunosuppressed tumor microenvironment and correlates TGF-beta and Wnt/beta-catenin signaling as predictive of low PD-L1 expression Cancer Research. 79: 1176-1176. DOI: 10.1158/1538-7445.Sabcs18-1176  0.335
2018 Federico L, Yang L, Brandon J, Panchatcharam M, Ren H, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice. Plos One. 13: e0198063. PMID 29889835 DOI: 10.1371/Journal.Pone.0198063  0.536
2018 McGrail DJ, Federico L, Li Y, Dai H, Lu Y, Mills GB, Yi S, Lin SY, Sahni N. Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers. Nature Communications. 9: 1317. PMID 29615613 DOI: 10.1038/S41467-018-03730-X  0.311
2018 Federico L, Haymaker CL, Forget M, Ravelli A, Bhatta A, Karpinets T, Zhang R, Weissferdt A, Fang B, Zhang J, Cascone T, Vaporciyan AA, Futreal A, Wistuba II, Sepesi B, et al. A preclinical study of tumor-infiltrating lymphocytes in NSCLC. Journal of Clinical Oncology. 36: 161-161. DOI: 10.1200/Jco.2018.36.5_Suppl.161  0.342
2018 Sepesi B, Federico L, Mitchell K, Parra E, Francisco Cruz A, Ravelli A, Haymaker C, Karpinets T, Cascone T, Weissferdt A, Antonoff M, Walsh G, Bernatchez C, Roth J, Zhang J, et al. P1.03-12 PD-L1 Expression is Predominant in CD68+ Tumor-Associated Macrophages in Stage I-III Non-Small Cell Lung Cancers Journal of Thoracic Oncology. 13: S516. DOI: 10.1016/J.Jtho.2018.08.693  0.301
2017 Federico L, Chong Z, Zhang D, McGrail DJ, Zhao W, Jeong KJ, Vellano CP, Ju Z, Gagea M, Liu S, Mitra S, Dennison JB, Lorenzi PL, Cardnell R, Diao L, et al. A murine preclinical syngeneic transplantation model for breast cancer precision medicine. Science Advances. 3: e1600957. PMID 28439535 DOI: 10.1126/Sciadv.1600957  0.31
2017 Peters HL, Tripathi SC, Kerros C, Katayama H, Garber HR, St John LS, Federico L, Meraz IM, Roth JA, Sepesi B, Majidi M, Ruisaard K, Clise-Dwyer K, Roszik J, Gibbons DL, et al. Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells. Cancer Immunology Research. PMID 28254787 DOI: 10.1158/2326-6066.Cir-16-0141  0.332
2017 Reuben A, Gittelman R, Zhang J, Chen R, Quek K, Vence L, Fernandez-Cubelo I, Behrens C, Gao J, Yusko E, Emerson R, Benzeno S, Vignali M, Tipton C, Jalali A, ... ... Federico L, et al. OA 13.05 Immune, Molecular and T Cell Repertoire Landscape of 235 Resected Non-Small Cell Lung Cancers and Paired Normal Lung Tissues Journal of Thoracic Oncology. 12: S1780. DOI: 10.1016/J.Jtho.2017.09.404  0.309
2017 Federico L, Haymaker C, Forget M, Vence L, Team I, Sharma P, Allison J, Fang B, Zhang J, Wagner H, Bogatenkova E, Wistuba I, Sepesi B, Heymach J, Gibbons DL, et al. P1.05-028 Phenotypic and Functional Profiling of Tumor-Infiltrating Lymphocytes (TIL) in Early Stage Non-Small Cell Lung Cancer (NSCLC) Journal of Thoracic Oncology. 12: S630-S631. DOI: 10.1016/J.Jtho.2016.11.812  0.333
2016 Mitra S, Federico L, Zhao W, Dennison J, Sarkar TR, Zhang F, Takiar V, Cheng KW, Mani S, Lee JS, Mills GB. Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT. Oncotarget. PMID 27259233 DOI: 10.18632/Oncotarget.9730  0.325
2016 Mitra S, Federico L, Mills GB. Abstract B40: Transcription factor Snail mediates EMT by altering vesicular trafficking protein Rab25 Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B40  0.366
2015 Federico L, Jeong KJ, Vellano CP, Mills GB. Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression. Journal of Lipid Research. PMID 25977291 DOI: 10.1194/Jlr.R060020  0.344
2015 Federico L, Jeong KJ, Zhang D, Ju Z, Chong Z, Dennison JB, Mills GB. Abstract P6-06-01: Studies on tumor heterogeneity using a preclinical model of breast cancer caused by genetic alteration of the ATX-LPA axis Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-06-01  0.319
2015 Mitra S, Federico L, Roysarkar T, Mani S, Mills GB. Abstract 4040: Transcription factor Snail mediates EMT by altering vesicular trafficking protein Rab25 Cancer Research. 75: 4040-4040. DOI: 10.1158/1538-7445.Am2015-4040  0.372
2014 Totani L, Piccoli A, Dell'Elba G, Concetta A, Di Santo A, Martelli N, Federico L, Pamuklar Z, Smyth SS, Evangelista V. Phosphodiesterase type 4 blockade prevents platelet-mediated neutrophil recruitment at the site of vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1689-96. PMID 24925970 DOI: 10.1161/Atvbaha.114.303939  0.557
2012 Federico L, Ren H, Mueller PA, Wu T, Liu S, Popovic J, Blalock EM, Sunkara M, Ovaa H, Albers HM, Mills GB, Morris AJ, Smyth SS. Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. Molecular Endocrinology (Baltimore, Md.). 26: 786-97. PMID 22474126 DOI: 10.1210/Me.2011-1229  0.516
2010 Ren H, Federico L, Huang H, Sunkara M, Drennan T, Frohman MA, Smyth SS, Morris AJ. A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis. Molecular Biology of the Cell. 21: 3171-81. PMID 20660155 DOI: 10.1091/Mbc.E10-01-0073  0.513
2010 Im E, Motiejunaite R, Aranda J, Park EY, Federico L, Kim TI, Clair T, Stracke ML, Smyth S, Kazlauskas A. Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression. Molecular and Cellular Biology. 30: 2401-10. PMID 20231358 DOI: 10.1128/Mcb.01275-09  0.557
2009 Morris AJ, Panchatcharam M, Cheng HY, Federico L, Fulkerson Z, Selim S, Miriyala S, Escalante-Alcalde D, Smyth SS. Regulation of blood and vascular cell function by bioactive lysophospholipids. Journal of Thrombosis and Haemostasis : Jth. 7: 38-43. PMID 19630765 DOI: 10.1111/J.1538-7836.2009.03405.X  0.561
2009 Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Fulerson Z, Berdyshev E, Natarajan V, Fang X, van Meeteren LA, Moolenaar WH, Mills GB, Morris AJ, et al. Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. The Journal of Biological Chemistry. 284: 7385-94. PMID 19139100 DOI: 10.1074/Jbc.M807820200  0.576
2009 Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Berdyshev E, Natarajan V, Fang X, Meeteren LAv, Moolenaar WH, Mills GB, Morris AJ, Smyth SS. Erratum: Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis (The Journal of Biological Chemistry (2009) vol. 284 (7385-7394)) Journal of Biological Chemistry. 284. DOI: 10.1074/Jbc.A807820200  0.51
2008 Federico L, Pamuklar Z, Smyth SS, Morris AJ. Therapeutic potential of autotaxin/lysophospholipase d inhibitors. Current Drug Targets. 9: 698-708. PMID 18691016 DOI: 10.2174/138945008785132439  0.576
2007 Evangelista V, Pamuklar Z, Piccoli A, Manarini S, Dell'elba G, Pecce R, Martelli N, Federico L, Rojas M, Berton G, Lowell CA, Totani L, Smyth SS. Src family kinases mediate neutrophil adhesion to adherent platelets. Blood. 109: 2461-9. PMID 17095622 DOI: 10.1182/Blood-2006-06-029082  0.562
2007 Federico L, Pamuklar Z, Liu S, Mills G, Morris A, Smyth S. Overexpression of the Plasma Lysophospholipase D Autotaxin Reveals a Novel Pathway for Regulation of Hemostasis in Mice. Blood. 110: 3649-3649. DOI: 10.1182/Blood.V110.11.3649.3649  0.55
2006 Totani L, Piccoli A, Manarini S, Federico L, Pecce R, Martelli N, Cerletti C, Piccardoni P, Lowell CA, Smyth SS, Berton G, Evangelista V. Src-family kinases mediate an outside-in signal necessary for beta2 integrins to achieve full activation and sustain firm adhesion of polymorphonuclear leucocytes tethered on E-selectin. The Biochemical Journal. 396: 89-98. PMID 16433632 DOI: 10.1042/Bj20051924  0.523
2004 Piccardoni P, Manarini S, Federico L, Bagoly Z, Pecce R, Martelli N, Piccoli A, Totani L, Cerletti C, Evangelista V. SRC-dependent outside-in signalling is a key step in the process of autoregulation of beta2 integrins in polymorphonuclear cells. The Biochemical Journal. 380: 57-65. PMID 14969582 DOI: 10.1042/Bj20040151  0.339
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