| Year |
Citation |
Score |
| 2024 |
Bullard BM, McDonald SJ, Cardaci TD, VanderVeen BN, Mohammed AD, Kubinak JL, Pierre JF, Chatzistamou I, Fan D, Hofseth LJ, Murphy EA. Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 38469632 DOI: 10.1152/ajpgi.00004.2024 |
0.349 |
|
| 2023 |
McDonald SJ, Bullard BM, VanderVeen BN, Cardaci TD, Huss AR, Fan D, Hofseth LJ, Murphy EA. Panaxynol Alleviates Colorectal Cancer in a Murine Model via Suppressing Macrophages and Inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 37489869 DOI: 10.1152/ajpgi.00119.2023 |
0.375 |
|
| 2020 |
Hofseth LJ, Hebert JR, Chanda A, Chen H, Love BL, Pena MM, Murphy EA, Sajish M, Sheth A, Buckhaults PJ, Berger FG. Publisher Correction: Early-onset colorectal cancer: initial clues and current views. Nature Reviews. Gastroenterology & Hepatology. PMID 32601393 DOI: 10.1038/S41575-020-0338-0 |
0.338 |
|
| 2020 |
Chaparala A, Tashkandi H, Chumanevich AA, Witalison EE, Windust A, Cui T, Nagarkatti M, Nagarkatti P, Hofseth LJ. Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2. Nutrients. 12. PMID 32575883 DOI: 10.3390/Nu12061850 |
0.474 |
|
| 2020 |
Chaparala A, Poudyal D, Tashkandi H, Witalison EE, Chumanevich AA, Hofseth JL, Nguyen I, Hardy O, Pittman DL, Wyatt MD, Windust A, Murphy EA, Nagarkatti M, Nagarkatti P, Hofseth LJ. Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice. Oncotarget. 11: 2026-2036. PMID 32547701 DOI: 10.18632/Oncotarget.27592 |
0.783 |
|
| 2020 |
Hofseth LJ, Hebert JR, Chanda A, Chen H, Love BL, Pena MM, Murphy EA, Sajish M, Sheth A, Buckhaults PJ, Berger FG. Early-onset colorectal cancer: initial clues and current views. Nature Reviews. Gastroenterology & Hepatology. PMID 32086499 DOI: 10.1038/S41575-019-0253-4 |
0.354 |
|
| 2018 |
Kadhim S, Singh NP, Zumbrun EE, Cui T, Chatterjee S, Hofseth L, Abood A, Nagarkatti P, Nagarkatti M. Resveratrol-Mediated Attenuation of Enterotoxin B-Induced Acute Liver Injury Is Associated With Regulation of microRNA and Induction of Myeloid-Derived Suppressor Cells. Frontiers in Microbiology. 9: 2910. PMID 30619104 DOI: 10.3389/Fmicb.2018.02910 |
0.346 |
|
| 2018 |
Zhang Q, Berger FG, Love B, Banister CE, Murphy EA, Hofseth LJ. Maternal stress and early-onset colorectal cancer. Medical Hypotheses. 121: 152-159. PMID 30396471 DOI: 10.1016/J.Mehy.2018.09.035 |
0.372 |
|
| 2017 |
Wirth MD, Sevoyan M, Hofseth L, Shivappa N, Hurley TG, Hébert JR. The Dietary Inflammatory Index is associated with elevated white blood cell counts in the National Health and Nutrition Examination Survey. Brain, Behavior, and Immunity. PMID 29217263 DOI: 10.1016/J.Bbi.2017.12.003 |
0.39 |
|
| 2017 |
Alhasson F, Das S, Seth R, Dattaroy D, Chandrashekaran V, Ryan CN, Chan LS, Testerman T, Burch J, Hofseth LJ, Horner R, Nagarkatti M, Nagarkatti P, Lasley SM, Chatterjee S. Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation. Plos One. 12: e0172914. PMID 28328972 DOI: 10.1371/Journal.Pone.0172914 |
0.344 |
|
| 2017 |
Shivappa N, Hébert JR, Steck SE, Hofseth LJ, Shehadah I, Bani-Hani KE, Al-Jaberi T, Al-Nusairr M, Heath D, Tayyem R. Dietary Inflammatory Index and odds of colorectal cancer in a case-control study from Jordan. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. PMID 28226219 DOI: 10.1139/Apnm-2017-0035 |
0.437 |
|
| 2017 |
Harmon BE, Wirth MD, Boushey CJ, Wilkens LR, Draluck E, Shivappa N, Steck SE, Hofseth L, Haiman CA, Le Marchand L, Hébert JR. The Dietary Inflammatory Index Is Associated with Colorectal Cancer Risk in the Multiethnic Cohort. The Journal of Nutrition. PMID 28179489 DOI: 10.3945/Jn.116.242529 |
0.37 |
|
| 2016 |
Chumanevich AA, Chaparala A, Witalison EE, Tashkandi H, Hofseth AB, Lane C, Pena E, Liu P, Pittman DL, Nagarkatti P, Nagarkatti M, Hofseth LJ, Chumanevich AA. Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds. Oncotarget. PMID 27974688 DOI: 10.18632/Oncotarget.13894 |
0.427 |
|
| 2016 |
Chumanevich AA, Witalison EE, Chaparala A, Chumanevich A, Nagarkatti P, Nagarkatti M, Hofseth LJ. Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties. Oncotarget. PMID 27447967 DOI: 10.18632/Oncotarget.10608 |
0.479 |
|
| 2015 |
Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin AR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, ... ... Hofseth LJ, et al. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology. 35: S276-304. PMID 26590477 DOI: 10.1016/J.Semcancer.2015.09.007 |
0.739 |
|
| 2015 |
Witalison EE, Cui X, Causey CP, Thompson PR, Hofseth LJ. Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer. Oncotarget. PMID 26440311 DOI: 10.18632/Oncotarget.5937 |
0.439 |
|
| 2015 |
Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, ... ... Hofseth LJ, et al. A multi-targeted approach to suppress tumor-promoting inflammation. Seminars in Cancer Biology. PMID 25951989 DOI: 10.1016/J.Semcancer.2015.03.006 |
0.754 |
|
| 2015 |
Qu C, Li B, Lai Y, Li H, Windust A, Hofseth LJ, Nagarkatti M, Nagarkatti P, Wang XL, Tang D, Janicki JS, Tian X, Cui T. Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy. Journal of Ethnopharmacology. 168: 326-36. PMID 25882312 DOI: 10.1016/J.Jep.2015.04.004 |
0.315 |
|
| 2015 |
Witalison EE, Thompson PR, Hofseth LJ. Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation. Current Drug Targets. PMID 25642720 DOI: 10.2174/1389450116666150202160954 |
0.308 |
|
| 2015 |
Witalison EE, Cui X, Hofseth AB, Subramanian V, Causey CP, Thompson PR, Hofseth LJ. Inhibiting protein arginine deiminases has antioxidant consequences. The Journal of Pharmacology and Experimental Therapeutics. 353: 64-70. PMID 25635139 DOI: 10.1124/Jpet.115.222745 |
0.498 |
|
| 2015 |
Chaparala A, Poudyal D, Cui X, Li B, Witalison EE, Cui T, Hofseth LJ. Abstract 5503: Panaxynol, a potential treatment for colitis, selectively targets pro-inflammatory macrophages for DNA damage and apoptosis Cancer Research. 75: 5503-5503. DOI: 10.1158/1538-7445.Am2015-5503 |
0.797 |
|
| 2015 |
Witalison EE, Cui X, Causey CP, Thompson PR, Hofseth LJ. Abstract 238: Citrullination of miRNA regulators by PADs: A potential mechanism for the promotion of colitis and colitis-associated colorectal cancer Cancer Research. 75: 238-238. DOI: 10.1158/1538-7445.Am2015-238 |
0.381 |
|
| 2014 |
Witalison EE, Cui X, Thompson PR, Hofseth LJ. Abstract 3782: Cl-amidine, a PAD inhibitor, prevents UC and CRC in mice: Exploring novel mechanisms of miRNA and oxidative stress regulation Cancer Research. 74: 3782-3782. DOI: 10.1158/1538-7445.Am2014-3782 |
0.486 |
|
| 2013 |
Poudyal D, Cui X, Le PM, Hofseth AB, Windust A, Nagarkatti M, Nagarkatti PS, Schetter AJ, Harris CC, Hofseth LJ. A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng. Plos One. 8: e75034. PMID 24130681 DOI: 10.1371/Journal.Pone.0075034 |
0.754 |
|
| 2013 |
Cui X, Witalison EE, Chumanevich AP, Chumanevich AA, Poudyal D, Subramanian V, Schetter AJ, Harris CC, Thompson PR, Hofseth LJ. The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest. Plos One. 8: e53791. PMID 23308284 DOI: 10.1371/Journal.Pone.0053791 |
0.735 |
|
| 2012 |
Bicker KL, Anguish L, Chumanevich AA, Cameron MD, Cui X, Witalison E, Subramanian V, Zhang X, Chumanevich AP, Hofseth LJ, Coonrod SA, Thompson PR. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. Acs Medicinal Chemistry Letters. 3: 1081-1085. PMID 23420624 DOI: 10.1021/Ml300288D |
0.338 |
|
| 2012 |
Sohn JJ, Schetter AJ, Yfantis HG, Ridnour LA, Horikawa I, Khan MA, Robles AI, Hussain SP, Goto A, Bowman ED, Hofseth LJ, Bartkova J, Bartek J, Wogan GN, Wink DA, et al. Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease. Plos One. 7: e44156. PMID 22970173 DOI: 10.1371/Journal.Pone.0044156 |
0.459 |
|
| 2012 |
Poudyal D, Cui X, Mai Le P, Davis T, Hofseth AB, Jin Y, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. A limited role of p53 on the ability of a Hexane fraction of American ginseng to suppress mouse colitis. Journal of Biomedicine & Biotechnology. 2012: 785739. PMID 22899889 DOI: 10.1155/2012/785739 |
0.791 |
|
| 2012 |
Shaked H, Hofseth LJ, Chumanevich A, Chumanevich AA, Wang J, Wang Y, Taniguchi K, Guma M, Shenouda S, Clevers H, Harris CC, Karin M. Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 14007-12. PMID 22893683 DOI: 10.1073/Pnas.1211509109 |
0.377 |
|
| 2012 |
Cui X, Jin Y, Singh UP, Chumanevich AA, Harmon B, Cavicchia P, Hofseth AB, Kotakadi V, Poudyal D, Stroud B, Volate SR, Hurley TG, Hebert JR, Hofseth LJ. Suppression of DNA damage in human peripheral blood lymphocytes by a juice concentrate: a randomized, double-blind, placebo-controlled trial. Molecular Nutrition & Food Research. 56: 666-70. PMID 22383296 DOI: 10.1002/Mnfr.201100496 |
0.705 |
|
| 2012 |
Poudyal D, Le PM, Davis T, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms. Cancer Prevention Research (Philadelphia, Pa.). 5: 685-96. PMID 22293630 DOI: 10.1158/1940-6207.Capr-11-0421 |
0.793 |
|
| 2012 |
Singh UP, Singh NP, Singh B, Hofseth LJ, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS. Role of resveratrol-induced CD11b(+) Gr-1(+) myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3(+) T cells and amelioration of chronic colitis in IL-10(-/-) mice. Brain, Behavior, and Immunity. 26: 72-82. PMID 21807089 DOI: 10.1016/J.Bbi.2011.07.236 |
0.398 |
|
| 2012 |
Poudyal D, Le PM, Davis T, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. Hexane fraction of American ginseng suppresses colitis and colon cancer - Response Cancer Prevention Research. 5: 983. DOI: 10.1158/1940-6207.Capr-12-0169 |
0.735 |
|
| 2012 |
Poudyal D, Cui X, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Windust A, Nagarkatti M, Nagarkatti P, Hofseth LJ. Abstract LB-168: A hexane fraction of American ginseng suppresses colon cancer associated with colitis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-168 |
0.791 |
|
| 2011 |
Hofseth LJ, Matesic LE. Editorial: an apple a day keeps colitis away. Journal of Leukocyte Biology. 90: 1037-8. PMID 22131358 DOI: 10.1189/Jlb.0511262 |
0.444 |
|
| 2011 |
Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ. Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G929-38. PMID 21415415 DOI: 10.1152/Ajpgi.00435.2010 |
0.775 |
|
| 2011 |
Poudyal D, Windust A, Davis T, Chumanevich AA, Chumanevich A, Nagarkatti M, Nagarkatti PS, Wargovich MJ, Hofseth LJ. Abstract 4616: A hexane extract of American ginseng suppresses mouse colitis Cancer Research. 71: 4616-4616. DOI: 10.1158/1538-7445.Am2011-4616 |
0.783 |
|
| 2010 |
Cui X, Jin Y, Poudyal D, Chumanevich AA, Davis T, Windust A, Hofseth A, Wu W, Habiger J, Pena E, Wood P, Nagarkatti M, Nagarkatti PS, Hofseth L. Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis. Carcinogenesis. 31: 1734-41. PMID 20729391 DOI: 10.1093/Carcin/Bgq163 |
0.767 |
|
| 2010 |
Chumanevich AA, Poudyal D, Cui X, Davis T, Wood PA, Smith CD, Hofseth LJ. Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase. Carcinogenesis. 31: 1787-93. PMID 20688834 DOI: 10.1093/Carcin/Bgq158 |
0.763 |
|
| 2010 |
Li J, Ichikawa T, Jin Y, Hofseth LJ, Nagarkatti P, Nagarkatti M, Windust A, Cui T. An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes. Journal of Ethnopharmacology. 130: 222-30. PMID 20447451 DOI: 10.1016/J.Jep.2010.03.040 |
0.34 |
|
| 2010 |
Hofseth LJ, Singh UP, Singh NP, Nagarkatti M, Nagarkatti PS. Taming the beast within: resveratrol suppresses colitis and prevents colon cancer. Aging. 2: 183-4. PMID 20436227 DOI: 10.18632/aging.100143 |
0.372 |
|
| 2010 |
Jin Y, Cui X, Singh UP, Chumanevich AA, Harmon B, Cavicchia P, Hofseth AB, Kotakadi V, Stroud B, Volate SR, Hurley TG, Hebert JR, Hofseth LJ. Systemic inflammatory load in humans is suppressed by consumption of two formulations of dried, encapsulated juice concentrate. Molecular Nutrition & Food Research. 54: 1506-14. PMID 20425759 DOI: 10.1002/Mnfr.200900579 |
0.39 |
|
| 2010 |
Cui X, Jin Y, Hofseth AB, Pena E, Habiger J, Chumanevich A, Poudyal D, Nagarkatti M, Nagarkatti PS, Singh UP, Hofseth LJ. Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prevention Research (Philadelphia, Pa.). 3: 549-59. PMID 20332304 DOI: 10.1158/1940-6207.Capr-09-0117 |
0.794 |
|
| 2010 |
Jin Y, Hofseth AB, Cui X, Windust AJ, Poudyal D, Chumanevich AA, Matesic LE, Singh NP, Nagarkatti M, Nagarkatti PS, Hofseth LJ. American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells. Cancer Prevention Research (Philadelphia, Pa.). 3: 339-47. PMID 20179294 DOI: 10.1158/1940-6207.Capr-09-0116 |
0.763 |
|
| 2010 |
Singh UP, Singh NP, Singh B, Hofseth LJ, Price RL, Nagarkatti M, Nagarkatti PS. Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis. The Journal of Pharmacology and Experimental Therapeutics. 332: 829-39. PMID 19940103 DOI: 10.1124/Jpet.109.160838 |
0.439 |
|
| 2010 |
Hofseth LJ, Bailey A. Abstract 1152: A novel, practical method for improving the sensitivity and reproducibility of immunodetection Cancer Research. 70: 1152-1152. DOI: 10.1158/1538-7445.Am10-1152 |
0.312 |
|
| 2009 |
Guess J, Burch JB, Ogoussan K, Armstead CA, Zhang H, Wagner S, Hebert JR, Wood P, Youngstedt SD, Hofseth LJ, Singh UP, Xie D, Hrushesky WJ. Circadian disruption, Per3, and human cytokine secretion. Integrative Cancer Therapies. 8: 329-36. PMID 19926609 DOI: 10.1177/1534735409352029 |
0.312 |
|
| 2009 |
Jones LE, Ying L, Hofseth AB, Jelezcova E, Sobol RW, Ambs S, Harris CC, Espey MG, Hofseth LJ, Wyatt MD. Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis. 30: 2123-9. PMID 19864471 DOI: 10.1093/Carcin/Bgp256 |
0.33 |
|
| 2009 |
Ichikawa T, Li J, Nagarkatti P, Nagarkatti M, Hofseth LJ, Windust A, Cui T. American ginseng preferentially suppresses STAT/iNOS signaling in activated macrophages. Journal of Ethnopharmacology. 125: 145-50. PMID 19505555 DOI: 10.1016/J.Jep.2009.05.032 |
0.341 |
|
| 2009 |
Sohn J, Yfantis H, Hussain S, Khan M, Goto A, Bowman E, Hofseth L, Wogan G, Harris C. Accelerated DNA Damage Response in Inflammatory Bowel Disease: A molecular basis for Cellular Senescence and Cancer Susceptibility Inflammatory Bowel Diseases. 15: S29. DOI: 10.1097/00054725-200912002-00082 |
0.332 |
|
| 2008 |
Jin Y, Kotakadi VS, Ying L, Hofseth AB, Cui X, Wood PA, Windust A, Matesic LE, Pena EA, Chiuzan C, Singh NP, Nagarkatti M, Nagarkatti PS, Wargovich MJ, Hofseth LJ. American ginseng suppresses inflammation and DNA damage associated with mouse colitis. Carcinogenesis. 29: 2351-9. PMID 18802031 DOI: 10.1093/Carcin/Bgn211 |
0.459 |
|
| 2008 |
Hussain SP, He P, Subleski J, Hofseth LJ, Trivers GE, Mechanic L, Hofseth AB, Bernard M, Schwank J, Nguyen G, Mathe E, Djurickovic D, Haines D, Weiss J, Back T, et al. Nitric oxide is a key component in inflammation-accelerated tumorigenesis. Cancer Research. 68: 7130-6. PMID 18757428 DOI: 10.1158/0008-5472.Can-08-0410 |
0.391 |
|
| 2008 |
Kotakadi VS, Jin Y, Hofseth AB, Ying L, Cui X, Volate S, Chumanevich A, Wood PA, Price RL, McNeal A, Singh UP, Singh NP, Nagarkatti M, Nagarkatti PS, Matesic LE, ... ... Hofseth LJ, et al. Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis. 29: 1799-806. PMID 18567620 DOI: 10.1093/Carcin/Bgn143 |
0.514 |
|
| 2008 |
Hofseth LJ. Nitric oxide as a target of complementary and alternative medicines to prevent and treat inflammation and cancer. Cancer Letters. 268: 10-30. PMID 18440130 DOI: 10.1016/J.Canlet.2008.03.024 |
0.466 |
|
| 2008 |
Hegde VL, Hegde S, Cravatt BF, Hofseth LJ, Nagarkatti M, Nagarkatti PS. Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells. Molecular Pharmacology. 74: 20-33. PMID 18388242 DOI: 10.1124/Mol.108.047035 |
0.324 |
|
| 2007 |
Ying L, Hofseth AB, Browning DD, Nagarkatti M, Nagarkatti PS, Hofseth LJ. Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation. Cancer Research. 67: 9286-93. PMID 17909036 DOI: 10.1158/0008-5472.Can-07-2238 |
0.436 |
|
| 2007 |
Singh NP, Hegde VL, Hofseth LJ, Nagarkatti M, Nagarkatti P. Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor. Molecular Pharmacology. 72: 1508-21. PMID 17872969 DOI: 10.1124/Mol.107.038984 |
0.386 |
|
| 2007 |
Ying L, Hofseth LJ. An emerging role for endothelial nitric oxide synthase in chronic inflammation and cancer. Cancer Research. 67: 1407-10. PMID 17308075 DOI: 10.1158/0008-5472.Can-06-2149 |
0.402 |
|
| 2007 |
Hofseth LJ, Wargovich MJ. Inflammation, cancer, and targets of ginseng. The Journal of Nutrition. 137: 183S-185S. PMID 17182823 DOI: 10.1093/Jn/137.1.183S |
0.508 |
|
| 2007 |
Prueitt RL, Boersma BJ, Howe TM, Goodman JE, Thomas DD, Ying L, Pfiester CM, Yfantis HG, Cottrell JR, Lee DH, Remaley AT, Hofseth LJ, Wink DA, Ambs S. Inflammation and IGF-I activate the Akt pathway in breast cancer. International Journal of Cancer. 120: 796-805. PMID 17096325 DOI: 10.1002/Ijc.22336 |
0.363 |
|
| 2006 |
Hofseth LJ, Ying L. Identifying and defusing weapons of mass inflammation in carcinogenesis. Biochimica Et Biophysica Acta. 1765: 74-84. PMID 16169156 DOI: 10.1016/J.Bbcan.2005.08.005 |
0.493 |
|
| 2005 |
Staib F, Robles AI, Varticovski L, Wang XW, Zeeberg BR, Sirotin M, Zhurkin VB, Hofseth LJ, Hussain SP, Weinstein JN, Galle PR, Harris CC. The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress. Cancer Research. 65: 10255-64. PMID 16288013 DOI: 10.1158/0008-5472.Can-05-1714 |
0.401 |
|
| 2005 |
Ying L, Marino J, Hussain SP, Khan MA, You S, Hofseth AB, Trivers GE, Dixon DA, Harris CC, Hofseth LJ. Chronic inflammation promotes retinoblastoma protein hyperphosphorylation and E2F1 activation. Cancer Research. 65: 9132-6. PMID 16230367 DOI: 10.1158/0008-5472.Can-05-1358 |
0.445 |
|
| 2004 |
Hussain SP, Trivers GE, Hofseth LJ, He P, Shaikh I, Mechanic LE, Doja S, Jiang W, Subleski J, Shorts L, Haines D, Laubach VE, Wiltrout RH, Djurickovic D, Harris CC. Nitric oxide, a mediator of inflammation, suppresses tumorigenesis. Cancer Research. 64: 6849-53. PMID 15466171 DOI: 10.1158/0008-5472.Can-04-2201 |
0.419 |
|
| 2004 |
Goodman JE, Hofseth LJ, Hussain SP, Harris CC. Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease. Environmental and Molecular Mutagenesis. 44: 3-9. PMID 15199542 DOI: 10.1002/Em.20024 |
0.45 |
|
| 2004 |
Thomas DD, Espey MG, Ridnour LA, Hofseth LJ, Mancardi D, Harris CC, Wink DA. Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 101: 8894-9. PMID 15178764 DOI: 10.1073/Pnas.0400453101 |
0.329 |
|
| 2004 |
Hofseth LJ. The adaptive imbalance to genotoxic stress: genome guardians rear their ugly heads. Carcinogenesis. 25: 1787-93. PMID 15166091 DOI: 10.1093/Carcin/Bgh196 |
0.347 |
|
| 2004 |
Li CQ, Robles AI, Hanigan CL, Hofseth LJ, Trudel LJ, Harris CC, Wogan GN. Apoptotic signaling pathways induced by nitric oxide in human lymphoblastoid cells expressing wild-type or mutant p53. Cancer Research. 64: 3022-9. PMID 15126337 DOI: 10.1158/0008-5472.Can-03-1880 |
0.349 |
|
| 2004 |
Hofseth LJ, Hussain SP, Harris CC. p53: 25 years after its discovery. Trends in Pharmacological Sciences. 25: 177-81. PMID 15116721 DOI: 10.1016/J.Tips.2004.02.009 |
0.337 |
|
| 2004 |
Hussain SP, Amstad P, He P, Robles A, Lupold S, Kaneko I, Ichimiya M, Sengupta S, Mechanic L, Okamura S, Hofseth LJ, Moake M, Nagashima M, Forrester KS, Harris CC. p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis. Cancer Research. 64: 2350-6. PMID 15059885 DOI: 10.1158/0008-5472.Can-2287-2 |
0.33 |
|
| 2004 |
Zurer I, Hofseth LJ, Cohen Y, Xu-Welliver M, Hussain SP, Harris CC, Rotter V. The role of p53 in base excision repair following genotoxic stress. Carcinogenesis. 25: 11-9. PMID 14555612 DOI: 10.1093/Carcin/Bgg186 |
0.323 |
|
| 2003 |
Hofseth LJ, Khan MA, Ambrose M, Nikolayeva O, Xu-Welliver M, Kartalou M, Hussain SP, Roth RB, Zhou X, Mechanic LE, Zurer I, Rotter V, Samson LD, Harris CC. The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. The Journal of Clinical Investigation. 112: 1887-94. PMID 14679184 DOI: 10.1172/Jci19757 |
0.43 |
|
| 2003 |
Hofseth LJ, Hussain SP, Wogan GN, Harris CC. Nitric oxide in cancer and chemoprevention. Free Radical Biology & Medicine. 34: 955-68. PMID 12684081 DOI: 10.1016/S0891-5849(02)01363-1 |
0.365 |
|
| 2003 |
Hussain SP, Hofseth LJ, Harris CC. Radical causes of cancer. Nature Reviews. Cancer. 3: 276-85. PMID 12671666 DOI: 10.1038/Nrc1046 |
0.422 |
|
| 2003 |
Staib F, Hussain SP, Hofseth LJ, Wang XW, Harris CC. TP53 and liver carcinogenesis. Human Mutation. 21: 201-16. PMID 12619106 DOI: 10.1002/Humu.10176 |
0.31 |
|
| 2003 |
Hofseth LJ, Saito S, Hussain SP, Espey MG, Miranda KM, Araki Y, Jhappan C, Higashimoto Y, He P, Linke SP, Quezado MM, Zurer I, Rotter V, Wink DA, Appella E, et al. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proceedings of the National Academy of Sciences of the United States of America. 100: 143-8. PMID 12518062 DOI: 10.1073/Pnas.0237083100 |
0.433 |
|
| 2002 |
Wang XW, Hussain SP, Huo TI, Wu CG, Forgues M, Hofseth LJ, Brechot C, Harris CC. Molecular pathogenesis of human hepatocellular carcinoma. Toxicology. 181: 43-7. PMID 12505283 DOI: 10.1016/S0300-483X(02)00253-6 |
0.301 |
|
| 2002 |
Hussain SP, Hofseth LJ, Harris CC. Tumor suppressor genes: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment. Lung Cancer (Amsterdam, Netherlands). S7-15. PMID 11720736 DOI: 10.1016/S0169-5002(01)00339-7 |
0.375 |
|
| 2000 |
Hussain SP, Raja K, Amstad PA, Sawyer M, Trudel LJ, Wogan GN, Hofseth LJ, Shields PG, Billiar TR, Trautwein C, Hohler T, Galle PR, Phillips DH, Markin R, Marrogi AJ, et al. Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. Proceedings of the National Academy of Sciences of the United States of America. 97: 12770-5. PMID 11050162 DOI: 10.1073/Pnas.220416097 |
0.313 |
|
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