Robert W. Sobol - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacology, Cell Biology, Molecular Biology, Oncology, Biochemistry

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li J, Svilar D, McClellan S, Kim JH, Ahn EE, Vens C, Wilson DM, Sobol RW. DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity. Oncotarget. 9: 31719-31743. PMID 30167090 DOI: 10.18632/oncotarget.25859  0.68
2018 Sykora P, Witt KL, Revanna P, Smith-Roe SL, Dismukes J, Lloyd DG, Engelward BP, Sobol RW. Next generation high throughput DNA damage detection platform for genotoxic compound screening. Scientific Reports. 8: 2771. PMID 29426857 DOI: 10.1038/s41598-018-20995-w  0.32
2017 Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. Crosstalk between mismatch repair and base excision repair in human gastric cancer. Oncotarget. 8: 84827-84840. PMID 29156686 DOI: 10.18632/oncotarget.10185  0.56
2017 Nagel ZD, Engelward BP, Brenner DJ, Begley TJ, Sobol RW, Bielas JH, Stambrook PJ, Wei Q, Hu JJ, Terry MB, Dilworth C, McAllister KA, Reinlib L, Worth L, Shaughnessy DT. Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease. Mutation Research. 800: 14-28. PMID 28458064 DOI: 10.1016/j.mrfmmm.2017.03.007  0.32
2016 Braganza A, Li J, Zeng X, Yates NA, Dey NB, Andrews J, Clark J, Zamani L, Wang XH, St Croix C, O'Sullivan R, Garcia-Exposito L, Brodsky JL, Sobol RW. UBE3B is a Calmodulin-Regulated, Mitochondria-Associated E3 Ubiquitin Ligase. The Journal of Biological Chemistry. PMID 28003368 DOI: 10.1074/jbc.M116.766824  0.56
2016 Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. Crosstalk between mismatch repair and base excision repair in human gastric cancer. Oncotarget. PMID 27340774 DOI: 10.18632/oncotarget.10185  0.56
2015 Quiñones JL, Thapar U, Yu K, Fang Q, Sobol RW, Demple B. Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124145 DOI: 10.1073/pnas.1501101112  0.68
2015 Wang J, Li J, Santana-Santos L, Shuda M, Sobol RW, Van Houten B, Qian W. A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1. Molecular Oncology. 9: 488-502. PMID 25458053 DOI: 10.1016/j.molonc.2014.10.002  0.68
2015 Wendell SG, Golin-Bisello F, Wenzel S, Sobol RW, Holguin F, Freeman BA. 15-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy ω-3 fatty acids Journal of Biological Chemistry. 290: 5868-5880. DOI: 10.1074/jbc.M114.635151  0.68
2015 Chandran UR, Luthra S, Santana-Santos L, Mao P, Kim SH, Minata M, Li J, Benos PV, DeWang M, Hu B, Cheng SY, Nakano I, Sobol RW. Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells Genomics Data. 5: 333-336. DOI: 10.1016/j.gdata.2015.07.007  0.68
2014 Sobol RW. Preface. NAD metabolism and signaling: Critical pathways in bacteria, yeast and mammals influencing genome stability, cell survival and disease. Dna Repair. 23: 1-3. PMID 25454703 DOI: 10.1016/j.dnarep.2014.10.007  0.68
2014 Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nature Communications. 5: 5513. PMID 25423885 DOI: 10.1038/ncomms6513  0.68
2014 Fouquerel E, Sobol RW. ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death. Dna Repair. 23: 27-32. PMID 25283336 DOI: 10.1016/j.dnarep.2014.09.004  0.68
2014 Fouquerel E, Goellner EM, Yu Z, Gagné JP, Barbi de Moura M, Feinstein T, Wheeler D, Redpath P, Li J, Romero G, Migaud M, Van Houten B, Poirier GG, Sobol RW. ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. Cell Reports. 8: 1819-31. PMID 25220464 DOI: 10.1016/j.celrep.2014.08.036  0.68
2014 Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, et al. ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents. Cancer Discovery. 4: 1198-213. PMID 25100205 DOI: 10.1158/2159-8290.CD-14-0157  0.68
2014 Bennett GR, Peters R, Wang XH, Hanne J, Sobol RW, Bundschuh R, Fishel R, Yoder KE. Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference. Plos One. 9: e103164. PMID 25051054 DOI: 10.1371/journal.pone.0103164  0.68
2014 Choi YJ, Li H, Son MY, Wang XH, Fornsaglio JL, Sobol RW, Lee M, Vijg J, Imholz S, Dollé ME, van Steeg H, Reiling E, Hasty P. Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair. Plos One. 9: e86358. PMID 24466051 DOI: 10.1371/journal.pone.0086358  0.68
2014 Lan L, Nakajima S, Wei L, Sun L, Hsieh CL, Sobol RW, Bruchez M, Van Houten B, Yasui A, Levine AS. Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin. Nucleic Acids Research. 42: 2330-45. PMID 24293652 DOI: 10.1093/nar/gkt1233  0.68
2013 Kothandapani A, Sawant A, Dangeti VS, Sobol RW, Patrick SM. Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity. Nucleic Acids Research. 41: 7332-43. PMID 23761438 DOI: 10.1093/nar/gkt479  0.68
2013 Williams K, Sobol RW. Mutation research/fundamental and molecular mechanisms of mutagenesis: special issue: DNA repair and genetic instability. Mutation Research. 743: 1-3. PMID 23688353 DOI: 10.1016/j.mrfmmm.2013.04.009  0.68
2013 Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I. Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3. Proceedings of the National Academy of Sciences of the United States of America. 110: 8644-9. PMID 23650391 DOI: 10.1073/pnas.1221478110  0.68
2013 Joshi K, Banasavadi-Siddegowda Y, Mo X, Kim SH, Mao P, Kig C, Nardini D, Sobol RW, Chow LM, Kornblum HI, Waclaw R, Beullens M, Nakano I. MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells. Stem Cells (Dayton, Ohio). 31: 1051-63. PMID 23404835 DOI: 10.1002/stem.1358  0.68
2013 Li J, Braganza A, Sobol RW. Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation. Antioxidants & Redox Signaling. 18: 2429-43. PMID 23311711 DOI: 10.1089/ars.2012.5107  0.68
2013 Nagaria P, Svilar D, Brown AR, Wang XH, Sobol RW, Wyatt MD. SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress. Mutation Research. 743: 26-32. PMID 23253900 DOI: 10.1016/j.mrfmmm.2012.12.001  0.68
2013 Iyer P, Srinivasan A, Singh SK, Mascara GP, Zayitova S, Sidone B, Fouquerel E, Svilar D, Sobol RW, Bobola MS, Silber JR, Gold B. Synthesis and characterization of DNA minor groove binding alkylating agents. Chemical Research in Toxicology. 26: 156-68. PMID 23234400 DOI: 10.1021/tx300437x  0.68
2012 Li J, Luthra S, Wang XH, Chandran UR, Sobol RW. Transcriptional profiling reveals elevated Sox2 in DNA polymerase ß null mouse embryonic fibroblasts. American Journal of Cancer Research. 2: 699-713. PMID 23226616  0.56
2012 Sobol RW. Genome instability caused by a germline mutation in the human DNA repair gene POLB. Plos Genetics. 8: e1003086. PMID 23144636 DOI: 10.1371/journal.pgen.1003086  0.68
2012 Svilar D, Dyavaiah M, Brown AR, Tang JB, Li J, McDonald PR, Shun TY, Braganza A, Wang XH, Maniar S, St Croix CM, Lazo JS, Pollack IF, Begley TJ, Sobol RW. Alkylation sensitivity screens reveal a conserved cross-species functionome. Molecular Cancer Research : McR. 10: 1580-96. PMID 23038810 DOI: 10.1158/1541-7786.MCR-12-0168  0.68
2012 Svilar D, Vens C, Sobol RW. Quantitative, real-time analysis of base excision repair activity in cell lysates utilizing lesion-specific molecular beacons. Journal of Visualized Experiments : Jove. e4168. PMID 22895410 DOI: 10.3791/4168  0.68
2012 Srinivasan A, Wang L, Cline CJ, Xie Z, Sobol RW, Xie XQ, Gold B. Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors. Biochemistry. 51: 6246-59. PMID 22788932 DOI: 10.1021/bi300490r  0.68
2012 Sobol RW. For MutY, it's all about the OG. Chemistry & Biology. 19: 313-4. PMID 22444586 DOI: 10.1016/j.chembiol.2012.03.002  0.68
2012 Goellner EM, Svilar D, Almeida KH, Sobol RW. Targeting DNA polymerase ß for therapeutic intervention. Current Molecular Pharmacology. 5: 68-87. PMID 22122465 DOI: 10.2174/1874467211205010068  0.68
2011 Mutamba JT, Svilar D, Prasongtanakij S, Wang XH, Lin YC, Dedon PC, Sobol RW, Engelward BP. XRCC1 and base excision repair balance in response to nitric oxide. Dna Repair. 10: 1282-93. PMID 22041025 DOI: 10.1016/j.dnarep.2011.10.008  0.68
2011 Yoder KE, Espeseth A, Wang XH, Fang Q, Russo MT, Lloyd RS, Hazuda D, Sobol RW, Fishel R. The base excision repair pathway is required for efficient lentivirus integration. Plos One. 6: e17862. PMID 21448280 DOI: 10.1371/journal.pone.0017862  0.68
2011 Li H, Wang P, Sun Q, Ding WX, Yin XM, Sobol RW, Stolz DB, Yu J, Zhang L. Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Research. 71: 3625-34. PMID 21444671 DOI: 10.1158/0008-5472.CAN-10-4475  0.68
2011 Langevin SM, Stone RA, Bunker CH, Lyons-Weiler MA, LaFramboise WA, Kelly L, Seethala RR, Grandis JR, Sobol RW, Taioli E. MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck. Cancer. 117: 1454-62. PMID 21425146 DOI: 10.1002/cncr.25689  0.68
2011 Goellner EM, Grimme B, Brown AR, Lin YC, Wang XH, Sugrue KF, Mitchell L, Trivedi RN, Tang JB, Sobol RW. Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. Cancer Research. 71: 2308-17. PMID 21406402 DOI: 10.1158/0008-5472.CAN-10-3213  0.68
2011 Tang JB, Svilar D, Trivedi RN, Wang XH, Goellner EM, Moore B, Hamilton RL, Banze LA, Brown AR, Sobol RW. N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Neuro-Oncology. 13: 471-86. PMID 21377995 DOI: 10.1093/neuonc/nor011  0.68
2011 Kothandapani A, Dangeti VS, Brown AR, Banze LA, Wang XH, Sobol RW, Patrick SM. Novel role of base excision repair in mediating cisplatin cytotoxicity. The Journal of Biological Chemistry. 286: 14564-74. PMID 21357694 DOI: 10.1074/jbc.M111.225375  0.68
2011 Lisovich A, Chandran UR, Lyons-Weiler MA, LaFramboise WA, Brown AR, Jakacki RI, Pollack IF, Sobol RW. A novel SNP analysis method to detect copy number alterations with an unbiased reference signal directly from tumor samples. Bmc Medical Genomics. 4: 14. PMID 21269491 DOI: 10.1186/1755-8794-4-14  0.68
2011 Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Lyons-Weiler MA, LaFramboise WA, Burger PC, Brat DJ, Rosenblum MK, Holmes EJ, Zhou T, Jakacki RI. IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 27: 87-94. PMID 20725730 DOI: 10.1007/s00381-010-1264-1  0.68
2011 Svilar D, Goellner EM, Almeida KH, Sobol RW. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxidants & Redox Signaling. 14: 2491-507. PMID 20649466 DOI: 10.1089/ars.2010.3466  0.68
2010 Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Nikiforov YE, Lyons-Weiler MA, LaFramboise WA, Burger PC, Brat DJ, Rosenblum MK, Gilles FH, Yates AJ, Zhou T, Cohen KJ, Finlay JL, et al. Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group. Pediatric Blood & Cancer. 55: 1066-71. PMID 20589656 DOI: 10.1002/pbc.22634  0.68
2010 Langevin SM, Stone RA, Bunker CH, Grandis JR, Sobol RW, Taioli E. MicroRNA-137 promoter methylation in oral rinses from patients with squamous cell carcinoma of the head and neck is associated with gender and body mass index. Carcinogenesis. 31: 864-70. PMID 20197299 DOI: 10.1093/carcin/bgq051  0.68
2010 Jelezcova E, Trivedi RN, Wang XH, Tang JB, Brown AR, Goellner EM, Schamus S, Fornsaglio JL, Sobol RW. Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Mutation Research. 686: 57-67. PMID 20096707 DOI: 10.1016/j.mrfmmm.2010.01.016  0.68
2010 Tang JB, Goellner EM, Wang XH, Trivedi RN, St Croix CM, Jelezcova E, Svilar D, Brown AR, Sobol RW. Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. Molecular Cancer Research : McR. 8: 67-79. PMID 20068071 DOI: 10.1158/1541-7786.MCR-09-0411  0.68
2010 Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. DNA polymerase beta-dependent long patch base excision repair in living cells. Dna Repair. 9: 109-19. PMID 20006562 DOI: 10.1016/j.dnarep.2009.11.002  0.68
2009 Jones LE, Ying L, Hofseth AB, Jelezcova E, Sobol RW, Ambs S, Harris CC, Espey MG, Hofseth LJ, Wyatt MD. Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis. 30: 2123-9. PMID 19864471 DOI: 10.1093/carcin/bgp256  0.68
2009 Taioli E, Ragin C, Wang XH, Chen J, Langevin SM, Brown AR, Gollin SM, Garte S, Sobol RW. Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation. Bmc Cancer. 9: 354. PMID 19807915 DOI: 10.1186/1471-2407-9-354  0.68
2009 Yoshizawa K, Jelezcova E, Brown AR, Foley JF, Nyska A, Cui X, Hofseth LJ, Maronpot RM, Wilson SH, Sepulveda AR, Sobol RW. Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. Plos One. 4: e6493. PMID 19654874 DOI: 10.1371/journal.pone.0006493  0.68
2009 Ueda R, Kohanbash G, Sasaki K, Fujita M, Zhu X, Kastenhuber ER, McDonald HA, Potter DM, Hamilton RL, Lotze MT, Khan SA, Sobol RW, Okada H. Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 10746-51. PMID 19520829 DOI: 10.1073/pnas.0811817106  0.68
2008 Allen D, Herbert DC, McMahan CA, Rotrekl V, Sobol RW, Wilson SH, Walter CA. Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Biology of Reproduction. 79: 824-31. PMID 18650495 DOI: 10.1095/biolreprod.108.069104  0.68
2008 Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Winter B, Balkaya M, Gertz K, Gay SB, Cox D, Eckart S, Ahmadi M, Juckel G, Kempermann G, Hellweg R, et al. Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7219-30. PMID 18614692 DOI: 10.1523/JNEUROSCI.0940-08.2008  0.68
2008 Trivedi RN, Wang XH, Jelezcova E, Goellner EM, Tang JB, Sobol RW. Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide. Molecular Pharmacology. 74: 505-16. PMID 18477668 DOI: 10.1124/mol.108.045112  0.68
2008 Sobol RW. CHIPping away at base excision repair. Molecular Cell. 29: 413-5. PMID 18313379 DOI: 10.1016/j.molcel.2008.02.004  0.68
2007 Almeida KH, Sobol RW. A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. Dna Repair. 6: 695-711. PMID 17337257 DOI: 10.1016/j.dnarep.2007.01.009  0.68
2007 Chiosea S, Jelezcova E, Chandran U, Luo J, Mantha G, Sobol RW, Dacic S. Overexpression of Dicer in precursor lesions of lung adenocarcinoma. Cancer Research. 67: 2345-50. PMID 17332367 DOI: 10.1158/0008-5472.CAN-06-3533  0.68
2007 Sobol RW. DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota. Dna Repair. 6: 3-7. PMID 16979388 DOI: 10.1016/j.dnarep.2006.08.005  0.68
2007 Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Balkaya M, Gertz K, Eckart S, Hellweg R, Hoertnagl H, Jaenisch R, Endres M. Role of uracil misincorporation for neurogeneration and brain dysfunction incuded by chronic folate deficiency Journal of Cerebral Blood Flow and Metabolism. 27.  0.68
2006 Chiosea S, Jelezcova E, Chandran U, Acquafondata M, McHale T, Sobol RW, Dhir R. Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. The American Journal of Pathology. 169: 1812-20. PMID 17071602 DOI: 10.2353/ajpath.2006.060480  0.68
2006 Pollack IF, Hamilton RL, Sobol RW, Burnham J, Yates AJ, Holmes EJ, Zhou T, Finlay JL. O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 3431-7. PMID 16849758 DOI: 10.1200/JCO.2006.05.7265  0.68
2005 Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Research. 65: 6394-400. PMID 16024643 DOI: 10.1158/0008-5472.CAN-05-0715  0.68
2004 Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, Katchanov J, Mergenthaler P, Dirnagl U, Wilson SH, Meisel A, Jaenisch R. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of Clinical Investigation. 113: 1711-21. PMID 15199406 DOI: 10.1172/JCI20926  0.68
2003 Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR. Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Cancer Research. 63: 5799-807. PMID 14522902  0.68
2003 Sobol RW, Kartalou M, Almeida KH, Joyce DF, Engelward BP, Horton JK, Prasad R, Samson LD, Wilson SH. Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. The Journal of Biological Chemistry. 278: 39951-9. PMID 12882965 DOI: 10.1074/jbc.M306592200  0.68
2003 Sobol RW, Foley JF, Nyska A, Davidson MG, Wilson SH. Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. Dna Repair. 2: 609-22. PMID 12713817 DOI: 10.1016/S1568-7864(03)00026-0  0.68
2002 Horton JK, Baker A, Berg BJ, Sobol RW, Wilson SH. Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage. Dna Repair. 1: 317-33. PMID 12509250 DOI: 10.1016/S1568-7864(02)00008-3  0.68
2002 Lavrik OI, Kolpashchikov DM, Prasad R, Sobol RW, Wilson SH. Binary system for selective photoaffinity labeling of base excision repair DNA polymerases. Nucleic Acids Research. 30: e73. PMID 12136121  0.68
2002 Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 99: 6860-5. PMID 11983862 DOI: 10.1073/pnas.092662499  0.68
2001 Tomicic MT, Thust R, Sobol RW, Kaina B. DNA polymerase β mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage Cancer Research. 61: 7399-7403. PMID 11606369  0.68
2001 Sobol RW, Wilson SH. Mammalian DNA β-polymerase in base excision repair of alkylation damage Progress in Nucleic Acid Research and Molecular Biology. 68: 57-74. PMID 11554313  0.68
2001 Lavrik OI, Prasad R, Sobol RW, Horton JK, Ackerman EJ, Wilson SH. Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. The Journal of Biological Chemistry. 276: 25541-8. PMID 11340072 DOI: 10.1074/jbc.M102125200  0.68
2000 Wilson SH, Sobol RW, Beard WA, Horton JK, Prasad R, Vande Berg BJ. DNA polymerase beta and mammalian base excision repair. Cold Spring Harbor Symposia On Quantitative Biology. 65: 143-55. PMID 12760029  0.68
2000 Sobol RW, Prasad R, Evenski A, Baker A, Yang XP, Horton JK, Wilson SH. The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity. Nature. 405: 807-10. PMID 10866204 DOI: 10.1038/35015598  0.68
1999 Ochs K, Sobol RW, Wilson SH, Kaina B. Cells deficient in DNA polymerase β are hypersensitive to alkylating agentinduced apoptosis and chromosomal breakage Cancer Research. 59: 1544-1551. PMID 10197627  0.68
1998 Fortini P, Pascucci B, Parlanti E, Sobol RW, Wilson SH, Dogliotti E. Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells Biochemistry. 37: 3575-3580. PMID 9530283 DOI: 10.1021/bi972999h  0.68
1998 Chen KH, Yakes FM, Srivastava DK, Singhal RK, Sobol RW, Horton JK, Van Houten B, Wilson SH. Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. Nucleic Acids Research. 26: 2001-7. PMID 9518496 DOI: 10.1093/nar/26.8.2001  0.68
1998 Biade S, Sobol RW, Wilson SH, Matsumoto Y. Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA Journal of Biological Chemistry. 273: 898-902. PMID 9422747 DOI: 10.1074/jbc.273.2.898  0.68
1996 Sobol RW, Horton JK, Kühn R, Gu H, Singhal RK, Prasad R, Rajewsky K, Wilson SH. Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature. 379: 183-6. PMID 8538772 DOI: 10.1038/379183a0  0.68
1995 Sobol RW, Henderson EE, Kon N, Shao J, Hitzges P, Mordechai E, Reichenbach NL, Charubala R, Schirmeister H, Pfleiderer W. Inhibition of HIV-1 replication and activation of RNase L by phosphorothioate/phosphodiester 2',5'-oligoadenylate derivatives. The Journal of Biological Chemistry. 270: 5963-78. PMID 7890727 DOI: 10.1074/jbc.270.11.5963  0.68
1994 Suhadolnik RJ, Reichenbach NL, Hitzges P, Sobol RW, Peterson DL, Henry B, Ablashi DV, Müller WEG, Schröder HC, Carter WA, Strayer DR. Upregulation of the 2-5A synthetase/rnase l antiviral pathway associated with chronic fatigue syndrome Clinical Infectious Diseases. 18: S96-S104. PMID 8148461 DOI: 10.1093/clinids/18.Supplement_1.S96  0.68
1993 Sobol RW, Fisher WL, Reichenbach NL, Kumar A, Beard WA, Wilson SH, Charubala R, Pfleiderer W, Suhadolnik RJ. HIV-1 reverse transcriptase: inhibition by 2',5'-oligoadenylates. Biochemistry. 32: 12112-8. PMID 7692966  0.68
1993 Sobol RW, Charubala R, Pfleiderer W, Suhadolnik RJ. Chemical synthesis and biological characterization of phosphorothioate analogs of 2', 5'-3'-deoxyadenylate trimer. Nucleic Acids Research. 21: 2437-43. PMID 7685081 DOI: 10.1093/nar/21.10.2437  0.68
1991 Hubbell HR, Sheetz PC, Iogal SS, Brodsky I, Kariko K, Li SW, Suhadolnik RJ, Sobol RW. Heterogeneous nuclear RNA from hairy cell leukemia patients activates 2', 5' -oligoadenylate synthetase Anticancer Research. 11: 1927-1932. PMID 1768064  0.68
1991 Sobol RW, Suhadolnik RJ, Kumar A, Lee BJ, Hatfield DL, Wilson SH. Localization of a polynucleotide binding region in the HIV-1 reverse transcriptase: Implications for primer binding Biochemistry. 30: 10623-10631. PMID 1718424  0.68
1991 Müller WE, Weiler BE, Charubala R, Pfleiderer W, Leserman L, Sobol RW, Suhadolnik RJ, Schröder HC. Cordycepin analogues of 2',5'-oligoadenylate inhibit human immunodeficiency virus infection via inhibition of reverse transcriptase. Biochemistry. 30: 2027-33. PMID 1705437  0.68
1990 Suhadolnik RJ, Li SW, Sobol RW, Varnum JM. 2′,5′A synthetase: Allosteric activation by fructose 1,6-bisphosphate Biochemical and Biophysical Research Communications. 169: 1198-1203. PMID 2363721 DOI: 10.1016/0006-291X(90)92023-S  0.68
1990 Charachon G, Sobol RW, Bisbal C, Salehzada T, Silhol M, Charubala R, Pfleiderer W, Lebleu B, Suhadolnik RJ. Phosphorothioate analogues of (2'-5')(A)4: agonist and antagonist activities in intact cells. Biochemistry. 29: 2550-6. PMID 2159324  0.68
1989 Montefiori DC, Sobol RW, Li SW, Reichenbach NL, Suhadolnik RJ, Charubala R, Pfleiderer W, Modliszewski A, Robinson WE, Mitchell WM. Phosphorothioate and cordycepin analogues of 2',5'-oligoadenylate: inhibition of human immunodeficiency virus type 1 reverse transcriptase and infection in vitro. Proceedings of the National Academy of Sciences of the United States of America. 86: 7191-4. PMID 2476814  0.68
1989 Charubala R, Pfleiderer W, Sobol RW, Li SW, Suhadolnik RJ. Nucleotides. Chemical synthesis of adenylyl-(2'→5')-adenylyl-(2'→5')-8-azidoadenosine, and activation and photoaffinity labelling of RNase L by [32P]p5' A2'p5'N38A Helvetica Chimica Acta. 72: 1354-1361. DOI: 10.1002/hlca.19890720624  0.68
1988 Suhadolnik RJ, Karikó K, Sobol RW, Li SW, Reichenbach NL, Haley BE. 2- and 8-azido photoaffinity probes. 1. Enzymatic synthesis, characterization, and biological properties of 2- and 8-azido photoprobes of 2-5A and photolabeling of 2-5A binding proteins Biochemistry. 27: 8840-8846. PMID 3242613  0.68
1988 Suhadolnik RJ, Li SW, Sobol RW, Haley BE. 2- and 8-azido photoaffinity probes. 2. Studies on the binding process of 2-5A synthetase by photosensitive ATP analogues Biochemistry. 27: 8846-8851. PMID 2853970  0.68
1987 Karikó K, Li SW, Sobol RW, Suhadolnik RJ, Charubala R, Pfleiderer W. Phosphorothioate analogues of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates. Biochemistry. 26: 7136-42. PMID 3427063  0.68
1987 Karikó K, Sobol RW, Suhadolnik L, Li SW, Reichenbach NL, Suhadolnik RJ, Charubala R, Pfleiderer W. Phosphorothioate analogues of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease. Biochemistry. 26: 7127-35. PMID 3427062  0.68
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