Year |
Citation |
Score |
2023 |
Liu Z, Villareal L, Goodla L, Kim H, Falcon DM, Haneef M, Martin DR, Zhang L, Lee HJ, Kremer D, Lyssiotis CA, Shah YM, Lin HC, Lin HK, Xue X. Iron promotes glycolysis to drive colon tumorigenesis. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 166846. PMID 37579983 DOI: 10.1016/j.bbadis.2023.166846 |
0.559 |
|
2022 |
Kremer DM, Lyssiotis CA. Targeting allosteric regulation of cancer metabolism. Nature Chemical Biology. 18: 441-450. PMID 35484254 DOI: 10.1038/s41589-022-00997-6 |
0.63 |
|
2021 |
Kim PK, Halbrook CJ, Kerk SA, Radyk M, Wisner S, Kremer DM, Sajjakulnukit P, Andren A, Hou SW, Trivedi A, Thurston G, Anand A, Yan L, Salamanca-Cardona L, Welling SD, et al. Hyaluronic acid fuels pancreatic cancer cell growth. Elife. 10. PMID 34951587 DOI: 10.7554/eLife.62645 |
0.782 |
|
2021 |
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, et al. GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nature Communications. 12: 4860. PMID 34381026 DOI: 10.1038/s41467-021-24859-2 |
0.77 |
|
2020 |
Bian Y, Li W, Kremer DM, Sajjakulnukit P, Li S, Crespo J, Nwosu ZC, Zhang L, Czerwonka A, Pawłowska A, Xia H, Li J, Liao P, Yu J, Vatan L, et al. Cancer SLC43A2 alters T cell methionine metabolism and histone methylation. Nature. PMID 32879489 DOI: 10.1038/S41586-020-2682-1 |
0.552 |
|
2020 |
Khoa LTP, Tsan YC, Mao F, Kremer DM, Sajjakulnukit P, Zhang L, Zhou B, Tong X, Bhanu NV, Choudhary C, Garcia BA, Yin L, Smith GD, Saunders TL, Bielas SL, et al. Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell. PMID 32610040 DOI: 10.1016/J.Stem.2020.06.005 |
0.499 |
|
2020 |
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.). 368: 85-89. PMID 32241947 DOI: 10.1126/Science.Aaw9872 |
0.74 |
|
2020 |
Nelson BS, Lin L, Kremer DM, Sousa CM, Cotta-Ramusino C, Myers A, Ramos J, Gao T, Kovalenko I, Wilder-Romans K, Dresser J, Davis M, Lee HJ, Nwosu ZC, Campit S, et al. Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy. Cancer & Metabolism. 8: 1. PMID 31908776 DOI: 10.1186/S40170-019-0202-2 |
0.708 |
|
2019 |
Lee HJ, Kremer DM, Sajjakulnukit P, Zhang L, Lyssiotis CA. A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics. Metabolomics : Official Journal of the Metabolomic Society. 15: 103. PMID 31289941 DOI: 10.1007/s11306-019-1564-8 |
0.489 |
|
2019 |
Xu J, Reznik E, Lee HJ, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra JG, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka ZP, Casuscelli J, et al. Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma. Elife. 8. PMID 30924768 DOI: 10.7554/Elife.38986 |
0.78 |
|
2019 |
Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, et al. Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer. Cell Metabolism. PMID 30827862 DOI: 10.1016/J.Cmet.2019.02.001 |
0.75 |
|
2019 |
Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, ... ... Kremer DM, et al. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Science Translational Medicine. 11. PMID 30760578 DOI: 10.1126/Scitranslmed.Aaq1427 |
0.507 |
|
2019 |
Yuan M, Kremer DM, Huang H, Breitkopf SB, Ben-Sahra I, Manning BD, Lyssiotis CA, Asara JM. Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS. Nature Protocols. PMID 30683937 DOI: 10.1038/S41596-018-0102-X |
0.528 |
|
2019 |
Xu J, Reznik E, Lee H, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra J, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka Z, Casuscelli J, et al. Author response: Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma Elife. DOI: 10.7554/Elife.38986.025 |
0.381 |
|
2019 |
Goo LE, Yates JA, Little AC, Kremer D, Kovalenko I, Oliver CR, Westerhof T, Wu Z, Vandecan N, Bao L, Ulintz PJ, Lyssiotis CA, Merajver SD. Abstract 4363: Effects of the small GTPase RhoC on inflammatory breast cancer metabolism Cancer Research. 79: 4363-4363. DOI: 10.1158/1538-7445.Sabcs18-4363 |
0.462 |
|
2018 |
Holt MC, Assar Z, Beheshti Zavareh R, Lin L, Anglin J, Mashadova O, Haldar D, Mullarky E, Kremer DM, Cantley LC, Kimmelman AC, Stein AJ, Lairson LL, Lyssiotis CA. Biochemical Characterization and Structure-based Mutational Analysis Provides Insight into Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry. PMID 30365304 DOI: 10.2210/Pdb6Dnd/Pdb |
0.668 |
|
2018 |
Nelson BS, Kremer DM, Lyssiotis CA. New tricks for an old drug. Nature Chemical Biology. 14: 990-991. PMID 30297874 DOI: 10.1038/s41589-018-0137-x |
0.71 |
|
2018 |
Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, et al. Menin regulates the serine biosynthetic pathway in Ewing sarcoma. The Journal of Pathology. PMID 29672864 DOI: 10.1002/Path.5085 |
0.745 |
|
2018 |
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Daylan AEC, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, et al. Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma. Jci Insight. 3. PMID 29367463 DOI: 10.1172/Jci.Insight.97422 |
0.734 |
|
2016 |
Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. PMID 27706144 DOI: 10.1038/nature19851 |
0.78 |
|
2016 |
Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. PMID 27509858 DOI: 10.1038/Nature19084 |
0.797 |
|
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