| Year |
Citation |
Score |
| 2022 |
Sutherland HS, Choi PJ, Lu GL, Giddens AC, Tong AST, Franzblau SG, Cooper CB, Palmer BD, Denny WA. Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl--(Pyridin-2-ylmethyl)Pyrazolo[1,5-]Pyrimidin-7-Amines. Pharmaceuticals (Basel, Switzerland). 15. PMID 36145345 DOI: 10.3390/ph15091125 |
0.461 |
|
| 2019 |
Giddens AC, Gamage SA, Kendall JD, Lee WJ, Baguley BC, Buchanan CM, Jamieson SMF, Dickson JMJ, Shepherd PR, Denny WA, Rewcastle GW. Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic & Medicinal Chemistry. PMID 30850264 DOI: 10.1016/j.bmc.2019.02.050 |
0.448 |
|
| 2017 |
Gamage SA, Giddens AC, Tsang KY, Flanagan JU, Kendall JD, Lee WJ, Baguley BC, Buchanan CM, Jamieson SMF, Shepherd PR, Denny WA, Rewcastle GW. Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic & Medicinal Chemistry. PMID 28958845 DOI: 10.1016/J.Bmc.2017.09.025 |
0.503 |
|
| 2017 |
Rewcastle GW, Kolekar S, Buchanan CM, Gamage SA, Giddens AC, Tsang KY, Kendall JD, Singh R, Lee WJ, Smith GC, Han W, Matthews DJ, Denny WA, Shepherd PR, Jamieson SMF. Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors. Oncotarget. PMID 28537878 DOI: 10.18632/Oncotarget.17730 |
0.439 |
|
| 2016 |
Kendall JD, Giddens AC, Tsang KY, Marshall ES, Lill CL, Lee WJ, Kolekar S, Chao M, Malik A, Yu S, Chaussade C, Buchanan C, Jamieson SM, Rewcastle GW, Baguley BC, et al. Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective PI3 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27923617 DOI: 10.1016/J.Bmcl.2016.11.078 |
0.481 |
|
| 2016 |
Giddens AC, Lee HH, Lu GL, Miller CK, Guo J, Lewis Phillips GD, Pillow TH, Tercel M. Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates. Bioorganic & Medicinal Chemistry. PMID 27745990 DOI: 10.1016/J.Bmc.2016.09.068 |
0.397 |
|
| 2014 |
Rewcastle GW, Flanagan JU, Giddens AC, Gamage SA, Tsang SK, Kendall JD, Baguley BC, Buchanan CM, Matthews DJ, O'Farrell M, Jamieson SM, Denny WA, Shepherd PR. Abstract 1644: Design and discovery of PWT33597 (VDC-597), a dual inhibitor of PI3-kinase alpha and mTOR Cancer Research. 74: 1644-1644. DOI: 10.1158/1538-7445.Am2014-1644 |
0.376 |
|
| 2014 |
Kendall JD, Marshall AJ, Giddens AC, Tsang KY, Boyd M, Frédérick R, Lill CL, Lee WJ, Kolekar S, Chao M, Malik A, Yu S, Chaussade C, Buchanan CM, Rewcastle GW, et al. Novel pyrazolo[1,5-a]pyridines as PI3K inhibitors: Variation of the central linker group Medchemcomm. 5: 41-46. DOI: 10.1039/C3Md00221G |
0.453 |
|
| 2012 |
Kendall JD, Giddens AC, Tsang KY, Frédérick R, Marshall ES, Singh R, Lill CL, Lee WJ, Kolekar S, Chao M, Malik A, Yu S, Chaussade C, Buchanan C, Rewcastle GW, et al. Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR. Bioorganic & Medicinal Chemistry. 20: 58-68. PMID 22177407 DOI: 10.1016/J.Bmc.2011.11.031 |
0.479 |
|
| 2012 |
Lam CFC, Giddens AC, Chand N, Webb VL, Copp BR. Semi-synthesis of bioactive fluorescent analogues of the cytotoxic marine alkaloid discorhabdin C Tetrahedron. 68: 3187-3194. DOI: 10.1016/J.Tet.2012.02.052 |
0.524 |
|
| 2011 |
Matthews DJ, O'Farrell M, James J, Giddens AC, Rewcastle GW, Denny WA. Abstract 4485: Preclinical characterization of PWT33597, a dual inhibitor of PI3-kinase alpha and mTOR Cancer Research. 71: 4485-4485. DOI: 10.1158/1538-7445.Am2011-4485 |
0.37 |
|
| 2008 |
Giddens AC, Nielsen L, Boshoff HI, Tasdemir D, Perozzo R, Kaiser M, Wang F, Sacchettini JC, Copp BR. Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities Tetrahedron. 64: 1242-1249. DOI: 10.1016/J.Tet.2007.11.075 |
0.593 |
|
| 2008 |
Giddens AC, Nielsen L, Boshoff HI, Tasdemir D, Perozzo R, Kaiser M, Wang F, Sacchettini JC, Copp BR. ChemInform Abstract: Natural Product Inhibitors of Fatty Acid Biosynthesis: Synthesis of the Marine Microbial Metabolites Pseudopyronines A (Ia) and B (Ib) and Evaluation of Their Antiinfective Activities. Cheminform. 39. DOI: 10.1002/CHIN.200836218 |
0.55 |
|
| 2005 |
Giddens AC, Boshoff HIM, Franzblau SG, Barry CE, Copp BR. Antimycobacterial natural products: Synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline Tetrahedron Letters. 46: 7355-7357. DOI: 10.1016/J.Tetlet.2005.08.119 |
0.571 |
|
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