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Philipp Klahn, Ph.D./Dr. rer. nat. - Publications

Affiliations: 
2017-2022 Institute for Organic Chemistry Technische Universität Braunschweig 
 2022- Department of Chemistry and Molecular Biology University of Gothenburg, Gothenburg, Västra Götalands län, Sweden 
Area:
Natural Product Chemistry, Chemical Biology, Medicinal Chemistry
Website:
www.klahnlab.de
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kagho MD, Schmidt K, Lambert C, Kaufmann T, Jia L, Faix J, Rottner K, Stadler M, Stradal T, Klahn P. Comprehensive Cell Biological Investigation of Cytochalasin B Derivatives with Distinct Activities on the Actin Network. Journal of Natural Products. PMID 39392628 DOI: 10.1021/acs.jnatprod.4c00676  0.696
2024 Kunz KA, Springer BL, Klahn P, Aldemir H, Mohr F, Kirsch SF. Synthesis of -Substituted 1,2,3-Triazoles. Organic Letters. PMID 39378272 DOI: 10.1021/acs.orglett.4c03204  0.579
2024 Kaspar F, Eilert L, Staar S, Oung SW, Wolter M, Ganskow CSG, Kemper S, Klahn P, Jacob CR, Blankenfeldt W, Schallmey A. Biocatalytic Ether Lipid Synthesis by an Archaeal Glycerolprenylase. Angewandte Chemie (International Ed. in English). e202412597. PMID 39359010 DOI: 10.1002/anie.202412597  0.542
2023 Jian L, Zscherp R, Beutling U, Shen X, Xu S, Zhang X, Brönstrup M, Klahn P, Sun Q. Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. Journal of Medicinal Chemistry. PMID 37595020 DOI: 10.1021/acs.jmedchem.3c00549  0.76
2023 Zscherp R, Chakrabarti A, Lehmann AP, Schrey H, Zeng H, Collisi W, Klahn P. Design of non-cytotoxic 6,7-dihydroxycoumarin-5-carboxylates with antibiofilm activity against and . Organic & Biomolecular Chemistry. PMID 37067007 DOI: 10.1039/d3ob00303e  0.752
2023 Kanstrup C, Jimidar CC, Tomas J, Cutolo G, Crocoll C, Schuler M, Klahn P, Tatibouët A, Nour-Eldin HH. Artificial Fluorescent Glucosinolates (F-GSLs) Are Transported by the Glucosinolate Transporters GTR1/2/3. International Journal of Molecular Sciences. 24. PMID 36674437 DOI: 10.3390/ijms24020920  0.737
2022 Rohrbacher C, Zscherp R, Weck SC, Klahn P, Ducho C. Synthesis of an Antimicrobial Enterobactin-Muraymycin Conjugate for Improved Activity against Gram-negative Bacteria. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36222466 DOI: 10.1002/chem.202202408  0.772
2022 Kaspar F, Ganskow CSG, Eilert L, Klahn P, Schallmey A. Alternative Assay Reagents for UV-Spectroscopic Detection of (Pyro-)Phosphate with the PUB Module. Analytical Chemistry. 94: 8132-8135. PMID 35653578 DOI: 10.1021/acs.analchem.2c01404  0.275
2021 Jimidar CC, Grunenberg J, Karge B, Fuchs HLS, Brönstrup M, Klahn P. Masked Amino Trimethyl Lock (H N-TML) Systems: New Molecular Entities for the Development of Turn-On Fluorophores and Their Application in Hydrogen Sulfide (H S) Imaging in Human Cells. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34713944 DOI: 10.1002/chem.202103525  0.731
2021 Kagho MD, Hintersatz H, Ihle A, Zeng H, Schrey H, Colisi W, Klahn P, Stadler M, Bruhn C, Rüffer T, Lang H, Banert K. Total Synthesis via Biomimetic Late-Stage Heterocyclization: Assignment of the Relative Configuration and Biological Evaluation of the Nitraria Alkaloid (±)-Nitrabirine. The Journal of Organic Chemistry. PMID 34570972 DOI: 10.1021/acs.joc.1c01650  0.704
2021 Zscherp R, Coetzee J, Vornweg J, Grunenberg J, Herrmann J, Müller R, Klahn P. Biomimetic enterobactin analogue mediates iron-uptake and cargo transport into and . Chemical Science. 12: 10179-10190. PMID 34377407 DOI: 10.1039/d1sc02084f  0.757
2021 Bourgat Y, Mikolai C, Stiesch M, Klahn P, Menzel H. Enzyme-Responsive Nanoparticles and Coatings Made from Alginate/Peptide Ciprofloxacin Conjugates as Drug Release System. Antibiotics (Basel, Switzerland). 10. PMID 34072352 DOI: 10.3390/antibiotics10060653  0.289
2020 Klahn P. Cannabinoids-Promising Antimicrobial Drugs orIntoxicants with Benefits? Antibiotics (Basel, Switzerland). 9. PMID 32498408 DOI: 10.3390/Antibiotics9060297  0.37
2020 Klahn P. Cannabinoids‐Promising Antimicrobial Drugs or Intoxicants with Benefits? Antibiotics Mdpi. 9: 297. DOI: 10.3390/antibiotics9060297  0.236
2019 Prochnow H, Rox K, Birudukota NVS, Weichert L, Hotop SK, Klahn P, Mohr K, Franz S, Banda DH, Blockus S, Schreiber J, Haid S, Oeyen M, Martinez JP, Süssmuth RD, et al. Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis. Journal of Virology. PMID 31666384 DOI: 10.1128/Jvi.01471-19  0.685
2019 Klahn P, Fetz V, Ritter A, Collisi W, Hinkelmann B, Arnold T, Tegge W, Rox K, Hüttel S, Mohr KI, Wink J, Stadler M, Wissing J, Jänsch L, Brönstrup M. The nuclear export inhibitor aminoratjadone is a potent effector in extracellular-targeted drug conjugates. Chemical Science. 10: 5197-5210. PMID 31191875 DOI: 10.1039/C8Sc05542D  0.758
2019 Glindemann CP, Backenköhler A, Strieker M, Wittstock U, Klahn P. Synthesis and biochemical evaluation of an artificial, fluorescent glucosinolate (GSL). Chembiochem : a European Journal of Chemical Biology. PMID 30980446 DOI: 10.1002/Cbic.201900148  0.725
2018 Okoh OA, Klahn P. Trimethyl Lock - A Multifunctional Molecular Tool for Drug Delivery, Cellular Imaging and Stimuli-responsive Materials. Chembiochem : a European Journal of Chemical Biology. PMID 29888433 DOI: 10.1002/Cbic.201800269  0.763
2017 Klahn P, Brönstrup M. Bifunctional antimicrobial conjugates and hybrid antimicrobials. Natural Product Reports. 34: 832-885. PMID 28530279 DOI: 10.1039/C7Np00006E  0.734
2017 Klahn P, Brönstrup M. Bifunctional antimicrobial conjugates and hybrid antimicrobials Natural Product Reports. DOI: 10.1039/C7NP00006E  0.282
2016 Klahn P, Brönstrup M. New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development. Current Topics in Microbiology and Immunology. PMID 27704270 DOI: 10.1007/82_2016_501  0.734
2016 Sakthivel P, Sharma N, Klahn P, Gereke M, Bruder D. Abscisic Acid: A Phytohormone and Mammalian Cytokine as Novel Pharmacon with Potential for Future Development into Clinical Applications. Current Medicinal Chemistry. 23: 1549-70. PMID 27048335 DOI: 10.2174/0929867323666160405113129  0.383
2016 Nicolaou KC, Yin J, Mandal D, Erande RD, Klahn P, Jin M, Aujay M, Sandoval J, Gavrilyuk J, Vourloumis D. Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins. Journal of the American Chemical Society. PMID 26829208 DOI: 10.1021/Jacs.5B12557  0.775
2015 Haering AP, Klahn P, Juebermann M, Mohr F, Kirsch SF. ChemInform Abstract: Gold(I)-Catalyzed Heterocyclization of β-Alkynyl Hydroxamic Acids: Synthesis of Isoxazolidin-3-ones. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201521154  0.562
2015 Klahn P, Kirsch SF. ChemInform Abstract: IBX-Mediated Dehydrogenation of Substituted β-Oxonitriles. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201506179  0.525
2014 Klahn P, Erhardt H, Kotthaus A, Kirsch SF. The synthesis of α-azidoesters and geminal triazides. Angewandte Chemie (International Ed. in English). 53: 7913-7. PMID 24895221 DOI: 10.1002/Anie.201402433  0.637
2014 Häring AP, Klahn P, Jübermann M, Mohr F, Kirsch SF. Gold(I)-catalyzed heterocyclization of β-alkynyl hydroxamic acids: synthesis of isoxazolidin-3-ones Monatshefte FüR Chemie - Chemical Monthly. 146: 119-134. DOI: 10.1007/S00706-014-1319-1  0.621
2014 Klahn P, Kirsch SF. IBX-mediated dehydrogenation of substituted β-oxonitriles European Journal of Organic Chemistry. 2014: 3149-3155. DOI: 10.1002/Ejoc.201402007  0.615
2014 Klahn P, Erhardt H, Kotthaus A, Kirsch SF. Über die Synthese von α-Azidoestern und geminalen Triaziden Angewandte Chemie. 126: 8047-8051. DOI: 10.1002/Ange.201402433  0.549
2012 Klahn P, Duschek A, Liébert C, Kirsch SF. Total synthesis of (+)-cyperolone. Organic Letters. 14: 1250-3. PMID 22324453 DOI: 10.1021/Ol300058T  0.616
2012 Harschneck T, Hummel S, Kirsch SF, Klahn P. Practical azidation of 1,3-dicarbonyls. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 1187-93. PMID 22189938 DOI: 10.1002/Chem.201102680  0.659
2011 Kirsch S, Klahn P, Menz H. The Use of COP-OAc in the Catalyst-Controlled Syntheses of 1,3-Polyols Synthesis. 2011: 3592-3603. DOI: 10.1055/S-0031-1289574  0.56
2011 Klahn P, Kirsch SF. Electronic Fine-Tuning of Carbene Ligands and its Impact on Gold Catalysis Chemcatchem. 3: 649-652. DOI: 10.1002/Cctc.201000366  0.543
2010 Tasler S, Baumgartner R, Ammendola A, Schachtner J, Wieber T, Blisse M, Rath S, Zaja M, Klahn P, Quotschalla U, Ney P. Thienopyrimidines as β3-adrenoceptor agonists: hit-to-lead optimization. Bioorganic & Medicinal Chemistry Letters. 20: 6108-15. PMID 20833036 DOI: 10.1016/j.bmcl.2010.08.039  0.3
2009 Menz H, Binder JT, Crone B, Duschek A, Haug TT, Kirsch SF, Klahn P, Liébert C. Gold-catalyzed reactivity of 3-silyloxy-1,5-enynes: a synthetic tool for the synthesis of complex structures and its limitations Tetrahedron. 65: 1880-1888. DOI: 10.1016/J.Tet.2008.11.103  0.619
2009 Menz H, Binder JT, Crone B, Duschek A, Haug TT, Kirsch SF, Klahn P, Liebert C. ChemInform Abstract: Gold-Catalyzed Reactivity of 3-Silyloxy-1,5-enynes: A Synthetic Tool for the Synthesis of Complex Structures and Its Limitations. Cheminform. 40. DOI: 10.1002/CHIN.200927028  0.571
0 Klahn P. The Nuclear Export Inhibitor Aminoratjadone is a Potent Effector in Extracellular-Targeted Drug Conjugates . DOI: 10.1039/C8SC05542D  0.289
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