Kenneth P. Murphy - Publications

Affiliations: 
Biochemistry University of Iowa, Iowa City, IA 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Schrift GL, Waldron TT, Timmons MA, Ramaswamy S, Kearney WR, Murphy KP. Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group "N2" in recognition by a guanylyl-ribonuclease. Journal of Molecular Biology. 355: 72-84. PMID 16300786 DOI: 10.1016/j.jmb.2005.10.019  1
2005 Lewis EA, Murphy KP. Isothermal titration calorimetry. Methods in Molecular Biology (Clifton, N.J.). 305: 1-16. PMID 15939991 DOI: 10.1385/1-59259-912-5:001  1
2005 Waldron TT, Schrift GL, Murphy KP. The salt-dependence of a protein-ligand interaction: ion-protein binding energetics. Journal of Molecular Biology. 346: 895-905. PMID 15713470 DOI: 10.1016/j.jmb.2004.12.018  1
2003 Horn JR, Ramaswamy S, Murphy KP. Structure and energetics of protein-protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine proteases. Journal of Molecular Biology. 331: 497-508. PMID 12888355 DOI: 10.1016/S0022-2836(03)00783-6  1
2003 Waldron TT, Murphy KP. Stabilization of proteins by ligand binding: application to drug screening and determination of unfolding energetics. Biochemistry. 42: 5058-64. PMID 12718549 DOI: 10.1021/bi034212v  1
2003 Waldron TT, Modestou MA, Murphy KP. Anion binding to a protein-protein complex lacks dependence on net charge. Protein Science : a Publication of the Protein Society. 12: 871-4. PMID 12649444 DOI: 10.1110/ps.0230703  1
2002 Edgcomb SP, Murphy KP. Variability in the pKa of histidine side-chains correlates with burial within proteins. Proteins. 49: 1-6. PMID 12211010 DOI: 10.1002/prot.10177  1
2002 Horn JR, Brandts JF, Murphy KP. van't Hoff and calorimetric enthalpies II: effects of linked equilibria. Biochemistry. 41: 7501-7. PMID 12044184 DOI: 10.1021/bi025626b  1
2002 Zou Q, Bennion BJ, Daggett V, Murphy KP. The molecular mechanism of stabilization of proteins by TMAO and its ability to counteract the effects of urea. Journal of the American Chemical Society. 124: 1192-202. PMID 11841287 DOI: 10.1021/ja004206b  1
2001 Murphy KP. Stabilization of protein structure. Methods in Molecular Biology (Clifton, N.J.). 168: 1-16. PMID 11357621 DOI: 10.1385/1-59259-193-0:001  1
2001 Horn JR, Russell D, Lewis EA, Murphy KP. Van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: are there significant discrepancies? Biochemistry. 40: 1774-8. PMID 11327839 DOI: 10.1021/bi002408e  1
2001 Saadi I, Semina EV, Amendt BA, Harris DJ, Murphy KP, Murray JC, Russo AF. Identification of a dominant negative homeodomain mutation in Rieger syndrome. The Journal of Biological Chemistry. 276: 23034-41. PMID 11301317 DOI: 10.1074/jbc.M008592200  1
2001 Bastos M, Pease JH, Wemmer DE, Murphy KP, Connelly PR. Thermodynamics of the helix-coil transition: Binding of S15 and a hybrid sequence, disulfide stabilized peptide to the S-protein. Proteins. 42: 523-30. PMID 11170206 DOI: 10.1002/1097-0134(20010301)42:4<523::AID-PROT100>3.0.CO;2-B  1
2000 Edgcomb SP, Baker BM, Murphy KP. The energetics of phosphate binding to a protein complex. Protein Science : a Publication of the Protein Society. 9: 927-33. PMID 10850802 DOI: 10.1110/ps.9.5.927  1
2000 Edgcomb SP, Murphy KP. Structural energetics of protein folding and binding. Current Opinion in Biotechnology. 11: 62-6. PMID 10679345 DOI: 10.1016/S0958-1669(99)00055-5  1
1999 Murphy KP. Predicting binding energetics from structure: Looking beyond ΔG° Medicinal Research Reviews. 19: 333-339. PMID 10398929 DOI: 10.1002/(SICI)1098-1128(199907)19:4<333::AID-MED6>3.0.CO;2-5  1
1999 Murphy KP, Baker BM, Edgcomb SP, Horn JR. Structural energetics of serine protease inhibition Pure and Applied Chemistry. 71: 1207-1213.  1
1998 Baker BM, Murphy KP. Prediction of binding energetics from structure using empirical parameterization. Methods in Enzymology. 295: 294-315. PMID 9750224 DOI: 10.1016/S0076-6879(98)95045-5  1
1998 Zou Q, Habermann-Rottinghaus SM, Murphy KP. Urea effects on protein stability: hydrogen bonding and the hydrophobic effect. Proteins. 31: 107-15. PMID 9593185 DOI: 10.1002/(SICI)1097-0134(19980501)31:2<107::AID-PROT1>3.0.CO;2-J  1
1998 Carlson SA, Chatterjee TK, Murphy KP, Fisher RA. Mutation of a putative amphipathic α-helix in the third intracellular domain of the platelet-activating factor receptor disrupts receptor/G protein coupling and signalling Molecular Pharmacology. 53: 451-458. PMID 9495811  1
1997 Robertson AD, Murphy KP. Protein Structure and the Energetics of Protein Stability. Chemical Reviews. 97: 1251-1268. PMID 11851450  1
1997 Baker BM, Murphy KP. Dissecting the energetics of a protein-protein interaction: the binding of ovomucoid third domain to elastase. Journal of Molecular Biology. 268: 557-69. PMID 9159490 DOI: 10.1006/jmbi.1997.0977  1
1996 Murphy KP, Zhao Y, Kawai M. Molecular forces involved in force generation during skeletal muscle contraction Journal of Experimental Biology. 199: 2565-2571. PMID 9110950  1
1996 Pelton JG, Torchia DA, Remington SJ, Murphy KP, Meadow ND, Roseman S. Structures of active site histidine mutants of IIIGlc, a major signal-transducing protein in Escherichia coli. Effects on the mechanisms of regulation and phosphoryl transfer. The Journal of Biological Chemistry. 271: 33446-56. PMID 8969208 DOI: 10.1074/jbc.271.52.33446  1
1996 Baker BM, Murphy KP. Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry. Biophysical Journal. 71: 2049-55. PMID 8889179 DOI: 10.1016/S0006-3495(96)79403-1  1
1996 Habermann SM, Murphy KP. Energetics of hydrogen bonding in proteins: A model compound study Protein Science. 5: 1229-1239. PMID 8819156  1
1996 Swenson DC, Habermann SM, Murphy KP. Cyclo(L-alanyl-L-seryl).H2O and Cyclo-(glycyl-L-seryl) Acta Crystallographica Section C: Crystal Structure Communications. 52: 383-387.  1
1995 Murphy KP, Freire E. Thermodynamic strategies for rational protein and drug design Pharmaceutical Biotechnology. 7: 219-241. PMID 8564019  1
1995 Murphy KP. Noncovalent forces important to the conformational stability of protein structures Methods in Molecular Biology (Clifton, N.J.). 40: 1-34. PMID 7633518  1
1994 Murphy KP, Xie D, Thompson KS, Amzel LM, Freire E. Entropy in biological binding processes: estimation of translational entropy loss. Proteins. 18: 63-7. PMID 8146122 DOI: 10.1002/prot.340180108  1
1994 Murphy KP. Hydration and convergence temperatures: on the use and interpretation of correlation plots Biophysical Chemistry. 51: 311-326. DOI: 10.1016/0301-4622(94)00052-2  1
1993 Murphy KP, Xie D, Garcia KC, Amzel LM, Freire E. Structural energetics of peptide recognition: Angiotensin II/antibody binding Proteins: Structure, Function and Genetics. 15: 113-120. PMID 8441749 DOI: 10.1002/prot.340150203  1
1993 Murphy KP, Freire E. Structural energetics of protein stability and folding cooperativity Pure and Applied Chemistry. 65: 1939-1946. DOI: 10.1351/pac199365091939  1
1992 Freire E, Murphy KP, Sanchez-Ruiz JM, Galisteo ML, Privalov PL. The molecular basis of cooperativity in protein folding. Thermodynamic dissection of interdomain interactions in phosphoglycerate kinase Biochemistry. 31: 250-256. PMID 1731874  1
1992 Murphy KP, Bhakuni V, Xie D, Freire E. Molecular basis of co-operativity in protein folding. III. Structural identification of cooperative folding units and folding intermediates Journal of Molecular Biology. 227: 293-306. PMID 1522594 DOI: 10.1016/0022-2836(92)90699-K  1
1992 Murphy KP, Freire E. Thermodynamics of structural stability and cooperative folding behavior in proteins Advances in Protein Chemistry. 43: 313-361. PMID 1442323  1
1991 Murphy KP, Gill SJ. Solid model compounds and the thermodynamics of protein unfolding. Journal of Molecular Biology. 222: 699-709. PMID 1660931 DOI: 10.1016/0022-2836(91)90506-2  1
1990 Murphy KP, Privalov PL, Gill SJ. Common features of protein unfolding and dissolution of hydrophobic compounds. Science (New York, N.Y.). 247: 559-61. PMID 2300815  1
1990 Dill KA, Privalov PL, Gill SJ, Murphy KP. The meaning of hydrophobicity Science. 250: 297-298. PMID 2218535  1
1990 Murphy KP, Gill SJ. Group additivity thermodynamics for dissolution of solid cyclic dipeptides into water Thermochimica Acta. 172: 11-20. DOI: 10.1016/0040-6031(90)80555-D  1
1990 Gill SJ, Murphy KP, Robert CH. Partition function formalism for analyzing calorimetric experiments Journal of Chemical Education. 67: 928-931.  1
1989 Murphy KP, Gill SJ. Calorimetric measurement of the enthalpy of dissolution of diketopiperazine in water as a function of temperature Thermochimica Acta. 139: 279-290. DOI: 10.1016/0040-6031(89)87028-5  1
1989 Murphy KP, Gill SJ. Thermodynamics of dissolution of solid cyclic dipeptides containing hydrophobic side groups The Journal of Chemical Thermodynamics. 21: 903-913. DOI: 10.1016/0021-9614(89)90149-3  1
1988 Parody-Morreale A, Murphy KP, Di Cera E, Fall R, DeVries AL, Gill SJ. Inhibition of bacterial ice nucleators by fish antifreeze glycoproteins. Nature. 333: 782-3. PMID 3386720 DOI: 10.1038/333782a0  1
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