Anthony J. Kirby, PhD - Publications

Affiliations: 
Chemistry University of Cambridge, Cambridge, England, United Kingdom 
Area:
Physical Organic Chemistry

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Costa PFA, de Abreu R, Fontana AB, Fiedler HD, Kirby AJ, Quina FH, Nome F, Gerola AP. The role of hydrophobicity in supramolecular polymer/surfactant catalysts: An understandable model for enzymatic catalysis. Journal of Colloid and Interface Science. 588: 456-468. PMID 33429342 DOI: 10.1016/j.jcis.2020.12.081  0.512
2017 Gerola AP, Wanderlind EH, Gomes YS, Giusti LA, García-Río L, Nome RA, Kirby AJ, Fiedler HD, Nome F. Supramolecular Polymer/Surfactant Complexes as Catalysts for Phosphate Transfer Reactions Acs Catalysis. 7: 2230-2239. DOI: 10.1021/Acscatal.7B00097  0.566
2015 Kirby AJ, Nome F. Fundamentals of Phosphate Transfer. Accounts of Chemical Research. PMID 26075464 DOI: 10.1021/Acs.Accounts.5B00072  0.608
2015 Komarov IV, Yanik S, Ishchenko AY, Davies JE, Goodman JM, Kirby AJ. The most reactive amide as a transition-state mimic for cis-trans interconversion. Journal of the American Chemical Society. 137: 926-30. PMID 25533746 DOI: 10.1021/Ja511460A  0.327
2015 Kirby AJ, Souza BS, Nome F. Structure and reactivity of phosphate diesters. Dependence on the nonleaving group Canadian Journal of Chemistry. 93: 422-427. DOI: 10.1139/Cjc-2014-0358  0.606
2015 Aldersley MF, Joshi PC, Ott EL, McCallum SA, Kirby AJ. The introduction of P-F bonds using aqueous fluoride ion and a water soluble carbodiimide: a convenient alternative synthesis of phosphorofluoridates and phosphonofluoridates Tetrahedron Letters. 56: 5272-5274. DOI: 10.1016/J.Tetlet.2015.07.036  0.346
2014 Ishchenko AY, Yanik S, Rusanov EB, Komarov IV, Kirby AJ. An expedient and practical approach to functionalized 3-aza-, 3-oxa-, and 3-thiabicyclo[33.1]nonane systems Synthesis (Germany). 46. DOI: 10.1055/S-0034-1379456  0.368
2014 Aldersley MF, Joshi PC, Schwartz HM, Kirby AJ. The reaction of activated RNA species with aqueous fluoride ion: A convenient synthesis of nucleotide 5′-phosphorofluoridates and a note on the mechanism Tetrahedron Letters. 55: 1464-1466. DOI: 10.1016/J.Tetlet.2014.01.051  0.38
2013 Medeiros M, Wanderlind EH, Mora JR, Moreira R, Kirby AJ, Nome F. Major mechanistic differences between the reactions of hydroxylamine with phosphate di- and tri-esters. Organic & Biomolecular Chemistry. 11: 6272-84. PMID 23900489 DOI: 10.1039/C3Ob40988K  0.603
2013 Kirby AJ, Medeiros M, Mora JR, Oliveira PS, Amer A, Williams NH, Nome F. Intramolecular general base catalysis in the hydrolysis of a phosphate diester. Calculational guidance to a choice of mechanism. The Journal of Organic Chemistry. 78: 1343-53. PMID 23373989 DOI: 10.1021/Jo302498G  0.711
2013 Kirby AJ, Mora JR, Nome F. New light on phosphate transfer from triesters. Biochimica Et Biophysica Acta. 1834: 454-63. PMID 22575086 DOI: 10.1016/J.Bbapap.2012.04.010  0.607
2013 Medeiros M, Manfredi AM, Kirby AJ, Nome F. The spontaneous hydrolysis of 2-pyridyl phosphate is a good model for the special mechanism for the hydrolysis of phosphate monoester monoanions Journal of Physical Organic Chemistry. 26: 1044-1047. DOI: 10.1002/Poc.3165  0.61
2012 Medeiros M, Orth ES, Manfredi AM, Pavez P, Micke GA, Kirby AJ, Nome F. Dephosphorylation reactions of mono-, di-, and triesters of 2,4-dinitrophenyl phosphate with deferoxamine and benzohydroxamic acid. The Journal of Organic Chemistry. 77: 10907-13. PMID 23167539 DOI: 10.1021/Jo302374Q  0.624
2012 Mora JR, Kirby AJ, Nome F. Theoretical study of the importance of the spectator groups on the hydrolysis of phosphate triesters. The Journal of Organic Chemistry. 77: 7061-70. PMID 22835036 DOI: 10.1021/Jo301380V  0.59
2012 Babtie AC, Lima MF, Kirby AJ, Hollfelder F. Kinetic and computational evidence for an intermediate in the hydrolysis of sulfonate esters. Organic & Biomolecular Chemistry. 10: 8095-101. PMID 22832951 DOI: 10.1039/C2Ob25699A  0.646
2012 Delley RJ, Bandyopadhyay S, Fox MA, Schliehe C, Hodgson DR, Hollfelder F, Kirby AJ, O'Donoghue AC. peri-Dimethylamino substituent effects on proton transfer at carbon in α-naphthylacetate esters: a model for mandelate racemase. Organic & Biomolecular Chemistry. 10: 590-6. PMID 22108698 DOI: 10.1039/C1Ob06525D  0.698
2012 Orth ES, Medeiros M, Souza BS, Caon NB, Kirby AJ, Nome F. Reactions of substituted aspirins with amino acids Journal of Physical Organic Chemistry. 25: 939-945. DOI: 10.1002/Poc.2971  0.615
2011 Kirby AJ, Medeiros M, Oliveira PS, Orth ES, Brandão TA, Wanderlind EH, Amer A, Williams NH, Nome F. Activating water: important effects of non-leaving groups on the hydrolysis of phosphate triesters. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14996-5004. PMID 22106028 DOI: 10.1002/Chem.201101926  0.715
2011 Orth ES, Medeiros M, Bortolotto T, Terenzi H, Kirby AJ, Nome F. Dephosphorylation reactions with deferoxamine, a potential chemical nuclease. The Journal of Organic Chemistry. 76: 10345-8. PMID 22049907 DOI: 10.1021/Jo202074Y  0.574
2011 Orth ES, Wanderlind EH, Medeiros M, Oliveira PS, Vaz BG, Eberlin MN, Kirby AJ, Nome F. Phosphorylimidazole derivatives: potentially biosignaling molecules. The Journal of Organic Chemistry. 76: 8003-8. PMID 21861472 DOI: 10.1021/Jo2017394  0.507
2011 Medeiros M, Souza BS, Orth ES, Brandão TAS, Rocha W, Kirby AJ, Nome F. The reaction of hydroxylamine with aspirin Arkivoc. 2011: 461-476. DOI: 10.3998/Ark.5550190.0012.738  0.609
2010 Souza BS, Vitto R, Nome F, Kirby AJ, Bortoluzzi AJ. 3-Acet-oxy-2-naphthoic acid. Acta Crystallographica. Section E, Structure Reports Online. 66: o2848. PMID 21589033 DOI: 10.1107/S1600536810040365  0.553
2010 Orth ES, Brandão TA, Souza BS, Pliego JR, Vaz BG, Eberlin MN, Kirby AJ, Nome F. Intramolecular catalysis of phosphodiester hydrolysis by two imidazoles. Journal of the American Chemical Society. 132: 8513-23. PMID 20509675 DOI: 10.1021/Ja1034733  0.589
2010 Kirby AJ, Davies JE, Fox DJ, Hodgson DR, Goeta AE, Lima MF, Priebe JP, Santaballa JA, Nome F. Ammonia oxide makes up some 20% of an aqueous solution of hydroxylamine. Chemical Communications (Cambridge, England). 46: 1302-4. PMID 20449284 DOI: 10.1039/B923742A  0.499
2010 Kirby AJ, Marriott RE. Rapid intramolecular and C-O cleavage reactions of a phosphate triester catalysed by a neighbouring hydroxyl group Recueil Des Travaux Chimiques Des Pays-Bas. 115: 56-62. DOI: 10.1002/Recl.19961150111  0.429
2010 Wagenaar A, Kirby AJ, Engberts JBFN. Acid-catalyzed hydrolysis of benzenesulfonamides. Rate enhancements by ortho-alkyl substituents Recueil Des Travaux Chimiques Des Pays-Bas. 104: 203-205. DOI: 10.1002/Recl.19851040704  0.369
2010 Hollfelder F, Kirby AJ, Tawfik DS, Kikuchi K, Hilvert D. ChemInform Abstract: Characterization of Proton-Transfer Catalysis by Serum Albumins Cheminform. 31: no-no. DOI: 10.1002/chin.200018038  0.493
2009 Kirby AJ, Medeiros M, Oliveira PS, Brandão TA, Nome F. Activating water: efficient intramolecular general base catalysis of the hydrolysis of a phosphate triester. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 8475-9. PMID 19621399 DOI: 10.1002/Chem.200901096  0.58
2009 Kirby AJ, Tondo DW, Medeiros M, Souza BS, Priebe JP, Lima MF, Nome F. Efficient intramolecular general-acid catalysis of the reactions of alpha-effect nucleophiles and ammonia oxide with a phosphate triester. Journal of the American Chemical Society. 131: 2023-8. PMID 19159237 DOI: 10.1021/Ja808746F  0.581
2009 Kirby AJ, Manfredi AM, Souza BS, Medeiros M, Priebe JP, Brandão TAS, Nome F. Reactions of alpha-nucleophiles with a model phosphate diester Arkivoc. 2009: 28-38. DOI: 10.3998/Ark.5550190.0010.305  0.585
2009 Iddon L, Bragg RA, Harding JR, Pidathala C, Bacsa J, Kirby AJ, Stachulski AV. Syntheses and structures of anomeric quaternary ammonium β-glucosides and comments on the anomeric C-N bond lengths Tetrahedron. 65: 6396-6402. DOI: 10.1016/J.Tet.2009.05.086  0.339
2008 Kirby AJ, Hollfelder F. Biochemistry: Enzymes under the nanoscope. Nature. 456: 45-7. PMID 18987728 DOI: 10.1038/456045A  0.556
2008 Kirby AJ, Souza BS, Medeiros M, Priebe JP, Manfredi AM, Nome F. Hydroxylamine as an oxygen nucleophile. Chemical evidence from its reaction with a phosphate triester. Chemical Communications (Cambridge, England). 4428-9. PMID 18802579 DOI: 10.1039/B810408E  0.575
2007 Ferreira VBN, Bortoluzzi AJ, Kirby AJ, Nome F. 2-Allyloxy-5-chlorobenzoic acid Acta Crystallographica Section E: Structure Reports Online. 63: o2981. DOI: 10.1107/S1600536807024762  0.538
2007 Kirby A. Enzymatic Reaction Mechanisms. By Perry A. Frey and Adrian D. Hegeman. Angewandte Chemie International Edition. 46: 7922-7924. DOI: 10.1002/Anie.200785514  0.327
2007 Kirby A. Enzymatic Reaction Mechanisms. Von Perry A. Frey und Adrian D. Hegeman. Angewandte Chemie. 119: 8068-8070. DOI: 10.1002/Ange.200785514  0.327
2006 Kirby AJ, Lima MF, da Silva D, Roussev CD, Nome F. Efficient intramolecular general acid catalysis of nucleophilic attack on a phosphodiester. Journal of the American Chemical Society. 128: 16944-52. PMID 17177446 DOI: 10.1021/Ja066439U  0.626
2006 Kirby AJ, Davies JE, Brandão TA, da Silva PF, Rocha WR, Nome F. Hydroxylamine as an oxygen nucleophile. Structure and reactivity of ammonia oxide. Journal of the American Chemical Society. 128: 12374-5. PMID 16984161 DOI: 10.1021/Ja065147Q  0.533
2005 Kirby AJ, Dutta-Roy N, da Silva D, Goodman JM, Lima MF, Roussev CD, Nome F. Intramolecular general acid catalysis of phosphate transfer. nucleophilic attack by oxyanions on the PO3 2- group. Journal of the American Chemical Society. 127: 7033-40. PMID 15884947 DOI: 10.1021/Ja0502876  0.641
2005 Kirby AJ, Gesser JC, Hollfelder F, Priebe JP, Nome F. Intramolecular general acid catalysis of sulfate transfer - Nucleophilic attack by oxyanions on the so3 - group Canadian Journal of Chemistry. 83: 1629-1636. DOI: 10.1139/v05-172  0.697
2005 Brandão TAS, Priebe JP, Damasceno AS, Bortoluzzi AJ, Kirby AJ, Nome F. Bond length-reactivity correlations for sulfate monoesters. The crystal structure of potassium 4-nitrophenyl sulfate, C 6H 4KNO 6S Journal of Molecular Structure. 734: 205-209. DOI: 10.1016/J.Molstruc.2004.09.025  0.551
2005 Asaad N, Davies JE, Hodgson DRW, Kirby AJ, Van Vliet L, Ottavi L. The search for efficient intramolecular proton transfer from carbon: The kinetically silent intramolecular general base-catalysed elimination reaction of O-phenyl 8-dimethylamino-1-naphthaldoximes Journal of Physical Organic Chemistry. 18: 101-109. DOI: 10.1002/Poc.858  0.398
2004 Kaneti J, Kirby AJ, Koedjikov AH, Pojarlieff IG. Thorpe-Ingold effects in cyclizations to five-membered and six-membered rings containing planar segments. The rearrangement of N(1)-alkyl-substituted dihydroorotic acids to hydantoinacetic acids in base. Organic & Biomolecular Chemistry. 2: 1098-103. PMID 15034636 DOI: 10.1039/B400248B  0.41
2004 Kirby AJ, Lima MF, da Silva D, Nome F. Nucleophilic attack by oxyanions on a phosphate monoester dianion: the positive effect of a cationic general Acid. Journal of the American Chemical Society. 126: 1350-1. PMID 14759187 DOI: 10.1021/Ja038428W  0.616
2004 Blériot Y, Vadivel SK, Herrera AJ, Greig IR, Kirby AJ, Sinaÿ P. Synthesis and acid catalyzed hydrolysis of B2,5 type conformationally constrained glucopyranosides: Incorporation into a cellobiose analogue Tetrahedron. 60: 6813-6828. DOI: 10.1016/J.Tet.2004.06.009  0.34
2004 Greig IR, Kirby AJ. Free energy relationships and intramolecular general acid catalysis Journal of Physical Organic Chemistry. 17: 498-506. DOI: 10.1002/Poc.766  0.398
2003 Angelova VT, Kirby AJ, Koedjikov AH, Pojarlieff IG. Kinetics and mechanism of the cyclization of omega-(p-nitrophenyl)-hydantoic acid amides: steric hindrance to proton transfer causes a 10(4)-fold change in rate. Organic & Biomolecular Chemistry. 1: 859-65. PMID 12929371 DOI: 10.1039/B211040G  0.476
2003 Davies JE, Kirby AJ, Komarov IV. Structural correlations for nucleophilic addition to the C=O group: The solvation angle Helvetica Chimica Acta. 86: 1222-1233. DOI: 10.1002/Hlca.200390105  0.38
2003 Kirby AJ. Thermodynamics of Biochemical Reactions. By Robert A. Alberty. Angewandte Chemie International Edition. 42: 4428-4428. DOI: 10.1002/Anie.200385024  0.347
2002 Kirby AJ, Komarov IV, Bilenko VA, Davies JE, Rawson JM. Structure and chemistry of a zwitterionic amine-aldehyde adduct. Chemical Communications (Cambridge, England). 2106-7. PMID 12357800 DOI: 10.1039/B206639D  0.326
2002 Davies JE, Doltsinis NL, Kirby AJ, Roussev CD, Sprik M. Estimating pKa values for pentaoxyphosphoranes. Journal of the American Chemical Society. 124: 6594-9. PMID 12047179 DOI: 10.1021/Ja025779M  0.315
2002 Jones PG, Kirby AJ, Pilkington M. 2,2,2-Tris(cyclohexyloxy)-4,5-(2′,2′'-biphenylo)-1,3,2-dioxaphospholene Acta Crystallographica Section E Structure Reports Online. 58: o268-o269. DOI: 10.1107/S1600536802002398  0.309
2002 Asaad N, Kirby AJ. Concurrent nucleophilic and general acid catalysis of the hydrolysis of a phosphate triester Journal of the Chemical Society, Perkin Transactions 2. 1708-1712. DOI: 10.1039/B204609A  0.475
2002 Ronsin G, Kirby AJ, Rittenhouse S, Woodnutt G, Camilleri P. Structure and antimicrobial activity of new bile acid-based gemini surfactants Journal of the Chemical Society, Perkin Transactions 2. 1302-1306. DOI: 10.1039/B202552C  0.35
2002 Dean KES, Kirby AJ. Concerted general acid and nucleophilic catalysis of acetal hydrolysis. A simple model for the lysozyme mechanism Journal of the Chemical Society, Perkin Transactions 2. 428-432. DOI: 10.1039/B110948K  0.448
2002 Kirby AJ, Marriott RE. General base catalysis vs. medium effects in the hydrolysis of an RNA model Journal of the Chemical Society, Perkin Transactions 2. 422-427. DOI: 10.1039/B109325H  0.384
2002 Dean KES, Kirby AJ, Komarov IV. Torsional effects on reactivity in glycosyl transfer Journal of the Chemical Society, Perkin Transactions 2. 337-341. DOI: 10.1039/B106257N  0.347
2001 Bond AD, Kirby AJ, Rodriguez E. Efficient intramolecular general acid catalysis: a preview from a crystal structure. Chemical Communications (Cambridge, England). 2266-7. PMID 12240143 DOI: 10.1039/B107787B  0.373
2001 Hollfelder F, Kirby AJ, Tawfik DS. On the magnitude and specificity of medium effects in enzyme-like catalysts for proton transfer. The Journal of Organic Chemistry. 66: 5866-74. PMID 11511264 DOI: 10.1021/Jo015723V  0.606
2001 Kirby AJ, Wothers PD. Conformational equilibria involving 2-amino-1,3-dioxans: Steric control of the anomeric effect Arkivoc. 2001: 58-71. DOI: 10.3998/Ark.5550190.0002.C07  0.368
2000 Kirby AJ, Hollfelder F, Tawfik DS. Nonspecific catalysis by protein surfaces. Applied Biochemistry and Biotechnology. 83: 173-80; discussion 1. PMID 10826958 DOI: 10.1385/Abab:83:1-3:173  0.598
2000 Pérez-Juste J, Hollfelder F, Kirby AJ, Engberts JB. Vesicles accelerate proton transfer from carbon up to 850-fold. Organic Letters. 2: 127-30. PMID 10814263 DOI: 10.1021/Ol991215K  0.546
2000 Blagoeva IB, Kirby AJ, Kochiyashki II, Koedjikov AH, Pojarlieff IG, Toteva MM. A normal gem-dimethyl effect in the base-catalyzed cyclization of ω-(p-nitrophenyl)hydantoic acids: evidence for hindered proton transfer in the permethylated esters Journal of the Chemical Society-Perkin Transactions 1. 1953-1960. DOI: 10.1039/B002276O  0.457
2000 Hollfelder F, Kirby AJ, Tawfik DS, Kikuchi K, Hilvert D. Characterization of proton-transfer catalysis by serum albumins Journal of the American Chemical Society. 122: 1022-1029. DOI: 10.1021/Ja993471Y  0.614
2000 Hartwell E, Hodgson DRW, Kirby AJ. Exploring the Limits of Efficiency of Proton-Transfer Catalysis in Models and Enzymes Journal of the American Chemical Society. 122: 9326-9327. DOI: 10.1021/Ja002335M  0.313
1999 Kirby AJ, Komarov IV, Wothers PD, Feeder N, Jones PG. Stereoelectronic interactions between hetero-atoms Pure and Applied Chemistry. 71: 385-391. DOI: 10.1351/Pac199971030385  0.333
1999 Barber SE, Dean KE, Kirby AJ. A mechanism for efficient proton-transfer catalysis. Intramolecular general acid catalysis of the hydrolysis of 1-arylethyl ethers of salicylic acid Canadian Journal of Chemistry. 77: 792-801. DOI: 10.1139/V99-080  0.464
1999 Blagoeva IB, Kirby AJ, Koedjikov AH, Pojarlieff IG. Multiple changes in rate-determining step in the acid and base catalyzed cyclizations of ethyl N-(p-nitrophenyl)hydantoates caused by methyl substitution Canadian Journal of Chemistry. 77: 849-859. DOI: 10.1139/V99-079  0.438
1999 Kirby AJ, Komarov IV, Kowski K, Rademacher P. Distortion of the amide bond in amides and lactams. Photoelectron-spectrum and electronic structure of 3,5,7-trimethyl-1-azaadamantan-2-one, the most twisted amide Journal of the Chemical Society-Perkin Transactions 1. 1313-1316. DOI: 10.1039/A902321F  0.307
1998 Kirby AJ, Komarov IV, Wothers PD, Feeder N. The Most Twisted Amide: Structure and Reactions. Angewandte Chemie (International Ed. in English). 37: 785-786. PMID 29711382 DOI: 10.1002/(Sici)1521-3773(19980403)37:6<785::Aid-Anie785>3.0.Co;2-J  0.374
1998 Atay E, Blagoeva IB, Kirby AJ, Pojarlieff IG. On the disappearance of the gem-dimethyl effect: the base-catalysed cyclization of ethyl hydantoates† Journal of the Chemical Society-Perkin Transactions 1. 2289-2298. DOI: 10.1039/A802884B  0.451
1998 Tickle D, George A, Jennings K, Camilleri P, Kirby AJ. A study of the structure and chiral selectivity of micelles of two isomeric D-glucopyranoside-based surfactants Journal of the Chemical Society-Perkin Transactions 1. 467-474. DOI: 10.1039/A708418H  0.332
1998 Beckmann C, Kirby AJ, Kuusela S, Tickle DC. Mechanisms of catalysis by imidazole buffers of the hydrolysis and isomerisation of RNA models Journal of the Chemical Society-Perkin Transactions 1. 573-582. DOI: 10.1039/A707741F  0.46
1998 Kirby AJ, Komarov IV, Feeder N. Spontaneous, Millisecond Formation of a Twisted Amide from the Amino Acid, and the Crystal Structure of a Tetrahedral Intermediate Journal of the American Chemical Society. 120: 7101-7102. DOI: 10.1021/Ja980700S  0.343
1998 Kirby A, Komarov I, Wothers P, Feeder N. Struktur und Reaktionen von 3,6,9-Trimethyl-1-aza-2-adamantanon, dem am stärksten verdrillten Amid Angewandte Chemie. 110: 830-831. DOI: 10.1002/(Sici)1521-3757(19980316)110:6<830::Aid-Ange830>3.0.Co;2-K  0.313
1997 Deslongchamps P, Jones PG, Li S, Kirby AJ, Kuusela S, Ma Y. Stereoelectronic effects on reactivity. Crystal-structure–reactivity correlations for acetals with synperiplanar lone pairs Journal of the Chemical Society-Perkin Transactions 1. 2621-2626. DOI: 10.1039/A705142E  0.383
1997 Brown CJ, Kirby AJ. Efficiency of proton transfer catalysis. Intramolecular general acid catalysis of the hydrolysis of dialkyl acetals of benzaldehyde Journal of the Chemical Society-Perkin Transactions 1. 1081-1094. DOI: 10.1039/A700155J  0.448
1997 Genre-Grandpierre A, Tellier C, Loirat M, Blanchard D, Hodgson DR, Hollfelder F, Kirby AJ. Catalysis of the Kemp elimination by antibodies elicited against a cationic hapten Bioorganic & Medicinal Chemistry Letters. 7: 2497-2502. DOI: 10.1016/S0960-894X(97)10003-8  0.586
1996 Capasso S, Mazzarella L, Sorrentino G, Balboni G, Kirby AJ. Kinetics and mechanism of the cleavage of the peptide bond next to asparagine. Peptides. 17: 1075-7. PMID 8899829 DOI: 10.1016/0196-9781(96)00153-2  0.409
1996 Hollfelder F, Kirby AJ, Tawfik DS. Off-the-shelf proteins that rival tailor-made antibodies as catalysts. Nature. 383: 60-2. PMID 8779715 DOI: 10.1038/383060A0  0.572
1996 Koedjikov AH, Blagoeva IB, Pojarlieff IG, Kirby AJ. The gem-dimethyl effect on reactivities in cyclizations through tetrahedral intermediates. Cyclization of methyl-substituted methyl amides of 5-(p-nitrophenyl)hydantoic acids Journal of the Chemical Society-Perkin Transactions 1. 2479-2487. DOI: 10.1039/P29960002479  0.456
1996 Brown CJ, Kirby AJ. Efficient intramolecular general acid catalysis of the hydrolysis of a dialkyl acetal Chemical Communications. 2355-2356. DOI: 10.1039/Cc9960002355  0.456
1996 Kirby AJ. Enzyme Mechanisms, Models, and Mimics Angewandte Chemie International Edition in English. 35: 706-724. DOI: 10.1002/Anie.199607061  0.327
1995 Bedford CT, Kirby AJ, Logan CJ, Drummond JN. Structure-activity studies of sulfate transfer: the hydrolysis and aminolysis of 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Bioorganic & Medicinal Chemistry. 3: 167-72. PMID 7796050 DOI: 10.1016/0968-0896(95)00015-9  0.371
1995 Al-Lohedan HA, Kirby AJ. Solvent effects on aromatic nucleophilic substitution by the ANRORC mechanism. Hydrolysis of 2-chloro-3,5-dinitropyridine Journal of the Chemical Society-Perkin Transactions 1. 1283-1286. DOI: 10.1039/P29950001283  0.336
1995 Capasso S, Kirby AJ, Salvadori S, Sica F, Zagari A. Kinetics and mechanism of the reversible isomerization of aspartic acid residues in tetrapeptides Journal of the Chemical Society-Perkin Transactions 1. 437-442. DOI: 10.1039/P29950000437  0.415
1994 Dalby KN, Kirby AJ, Hollfelder F. Simple but efficient models for nuclease catalysis Pure and Applied Chemistry. 66: 687-694. DOI: 10.1351/Pac199466040687  0.779
1994 Camilleri P, Jones RFD, Kirby AJ, Strömberg R. Nucleophilic catalysis of glycoside hydrolysis. The hydrolysis of 4-nitrophenyl α- and β-D-glucopyranoside tetraphosphates Journal of the Chemical Society-Perkin Transactions 1. 2085-2090. DOI: 10.1039/P29940002085  0.365
1994 Kirby AJ, O'Carroll F. Highly efficient intramolecular general acid catalysis of enol ether hydrolysis, with rapid proton transfer to carbon Journal of the Chemical Society-Perkin Transactions 1. 649-655. DOI: 10.1039/P29940000649  0.433
1994 Kirby AJ, Williams NH. Efficient intramolecular general acid catalysis of enol ether hydrolysis. Hydrogen-bonding stabilisation of the transition state for proton transfer to carbon Journal of the Chemical Society, Perkin Transactions 2. 643-648. DOI: 10.1039/P29940000643  0.63
1994 Chandler AJ, Hollfelder F, Kirby AJ, O'Carroll F, Strömberg R. Models for enzyme-catalysed phosphate transfer: comparisons of reactivity towards a neighbouring hydroxy group for phosphodiester anions and acids. General base catalysis of the cyclisation of a hydroxyalkyl phosphate triester Journal of the Chemical Society-Perkin Transactions 1. 327-333. DOI: 10.1039/P29940000327  0.653
1994 Jones RFD, Camilleri P, Kirby AJ, Okafo GN. The synthesis and micellar properties of a novel anionic surfactant Journal of the Chemical Society, Chemical Communications. 1311-1312. DOI: 10.1039/C39940001311  0.321
1994 Kirby AJ, Strömberg R. Intramolecular nucleophilic catalysis of glucoside hydrolysis by the 2-phosphate group Journal of the Chemical Society, Chemical Communications. 709-710. DOI: 10.1039/C39940000709  0.378
1994 Kirby AJ, Parkinson A. Most efficient intramolecular general acid catalysis of acetal hydrolysis by the carboxy group Journal of the Chemical Society, Chemical Communications. 707-708. DOI: 10.1039/C39940000707  0.441
1993 Dalby KN, Kirby AJ, Hollfelder F. Models for nuclease catalysis: Mechanisms for general acid catalysis of the rapid intramolecular displacement of methoxide from a phosphate diester Journal of the Chemical Society-Perkin Transactions 1. 1269-1281. DOI: 10.1039/P29930001269  0.679
1992 Jones PG, Kirby AJ, Parker JK. Bond length and reactivity. The effect of β-silicon. Structure of the 3,5-dinitrobenzoate ester of trans-2-(dimethylphenylsilyl)cyclohexanol Acta Crystallographica Section C Crystal Structure Communications. 48: 868-871. DOI: 10.1107/S0108270191012283  0.316
1992 Jones PG, Kirby AJ, Parker JK. Bond length and reactivity. The effect of β-fluorine. Structure of the methanesulfonate ester of trans,trans-5-tert-butyl-2-fluorocyclohexanol Acta Crystallographica Section C Crystal Structure Communications. 48: 864-866. DOI: 10.1107/S010827019101226X  0.303
1992 Jones PG, Kirby AJ, Parker JK. Bond length and reactivity. The effect of β-fluorine. Structures of the 9-(9-phenylxanthenyl) ether, and the 4-phenylbenzoate, diphenyl phosphate and methanesulfonate esters of cis,trans-4-tert-butyl-2-fluorocyclohexanol Acta Crystallographica Section C Crystal Structure Communications. 48: 859-864. DOI: 10.1107/S0108270191012258  0.342
1992 Jones PG, Kirby AJ, Parker JK. Bond length and reactivity. The effect of β-fluorine. Structures of the 4-phenylbenzoate and methanesulfonate esters of trans,cis-4-tert-butyl-2-fluorocyclohexanol Acta Crystallographica Section C Crystal Structure Communications. 48: 855-858. DOI: 10.1107/S0108270191012246  0.318
1992 Kirby AJ, Parker JK, Raithby PR. Bond length and reactivity. Structure of 2-phenylethyl p-toluenesulfonate Acta Crystallographica Section C Crystal Structure Communications. 48: 832-834. DOI: 10.1107/S0108270191012167  0.301
1992 Jones PG, Schmidt-Bäse K, Edwards MR, Kirby AJ. Bond length and reactivity. Structure of 2-endo-bornyl p-toluenesulfonate Acta Crystallographica Section C Crystal Structure Communications. 48: 826-829. DOI: 10.1107/S0108270191012143  0.306
1992 Amos RD, Handy NC, Jones PG, Kirby AJ, Parker JK, Percy JM, Der Su M. Bond length and reactivity: The gauche effect. A combined crystallographic and theoretical investigation of the effects of β-substituents on C-OX bond length Journal of the Chemical Society, Perkin Transactions 2. 549-558. DOI: 10.1039/P29920000549  0.34
1992 Dalby KN, Hollfelder F, Kirby AJ. Electrostatic catalysis of the hydrolysis of a phosphate diester in water Journal of the Chemical Society, Chemical Communications. 1770-1771. DOI: 10.1039/C39920001770  0.763
1992 Chandler AJ, Kirby AJ. Intramolecular attack by the hydroxy group on phosphate diesters is both general acid and general base catalysed Journal of the Chemical Society, Chemical Communications. 1769-1770. DOI: 10.1039/C39920001769  0.445
1992 Kirby AJ, Williams NH. The anomeric effects of aryloxy groups Journal of the Chemical Society, Chemical Communications. 1286-1287. DOI: 10.1039/C39920001286  0.533
1992 Kirby AJ, Williams NH. Electronic effects on conformational preferences: A-values for aryloxy groups Journal of the Chemical Society, Chemical Communications. 1285-1286. DOI: 10.1039/C39920001285  0.527
1991 Kirby AJ, Williams NH. There is no evidence for electrostatic catalysis of vinyl ether hydrolysis in water Journal of the Chemical Society, Chemical Communications. 1644-1645. DOI: 10.1039/C39910001644  0.616
1991 Kirby AJ, Williams NH. Efficient intramolecular general acid catalysis of vinyl ether hydrolysis by the neighbouring carboxylic acid group Journal of the Chemical Society, Chemical Communications. 1643-1644. DOI: 10.1039/C39910001643  0.621
1990 Kirby AJ, Ryder H, Matassa V. Stabilisation of the thromboxane ring system by electron-withdrawing substituents. Mechanism and reactivity in the hydrolysis of alkyl and aryl oxetane acetals Journal of the Chemical Society-Perkin Transactions 1. 825-831. DOI: 10.1039/P29900000825  0.413
1990 Kirby AJ, Ryder H, Matassa V. Stabilisation of the thromboxane ring system by electron-withdrawing substituents: synthesis and attempted cyclisation of substituted tetrahydropyran-2,4-diols Journal of the Chemical Society-Perkin Transactions 1. 617-626. DOI: 10.1039/P19900000617  0.34
1989 Jones PG, Edwards MR, Kirby AJ. Bond length and reactivity. The pinacol rearrangement. 4. Structures of trans-2-hydroxycyclohexyl benzenesulfonate, p-toluenesulfonate and 2-naphthalenesulfonate Acta Crystallographica Section C Crystal Structure Communications. 45: 252-257. DOI: 10.1107/S0108270188011333  0.32
1989 Jones PG, Edwards MR, Kirby AJ. Bond length and reactivity. The pinacol rearrangement. 3. Structures of trans-2-hydroxycyclohexyl 4-nitrobenzoate and 2,4-dinitrobenzoate esters Acta Crystallographica Section C Crystal Structure Communications. 45: 249-252. DOI: 10.1107/S0108270188011321  0.347
1989 Jones PG, Edwards MR, Kirby AJ. Bond length and reactivity. The pinacol rearrangement. 1. Redetermination of the structure of trans-cyclohexane-1,2-diol Acta Crystallographica Section C Crystal Structure Communications. 45: 244-247. DOI: 10.1107/S010827018801131X  0.328
1989 Jones PG, Edwards MR, Kirby AJ. Bond length and reactivity. The pinacol rearrangement. 2. Structure of trans-2-phenoxycyclohexanol Acta Crystallographica Section C Crystal Structure Communications. 45: 247-249. DOI: 10.1107/S0108270188011308  0.321
1989 Jones PG, Kirby AJ, Ryder H. Bond length and reactivity. Structure of 2-(4-nitrophenoxy)tetrahydrofuran Acta Crystallographica Section C Crystal Structure Communications. 45: 239-241. DOI: 10.1107/S010827018801128X  0.303
1989 Jones PG, Kirby AJ, Parker JK. Bond length and reactivity: 1-arylethyl ethers and esters. 7. Structure of 1-[3,5-bis(trifluoromethyl)phenyl]ethyl 4-nitrobenzoate Acta Crystallographica Section C Crystal Structure Communications. 45: 218-221. DOI: 10.1107/S0108270188010200  0.366
1989 Jones PG, Schmidt-Bäse K, Kirby AJ, Parker JK. Bond length and reactivity. Structures of the triphenylmethyl ethers of 1-indanol and 5-methoxy-1-indanol Acta Crystallographica Section C Crystal Structure Communications. 45: 221-224. DOI: 10.1107/S0108270188010194  0.319
1989 Kirby AJ, Parker JK, Raithby PR. Bond length and reactivity. Structure of 1-indanol 4-nitrobenzoate ester Acta Crystallographica Section C Crystal Structure Communications. 45: 224-226. DOI: 10.1107/S0108270188010182  0.331
1989 Jones PG, Kirby AJ, Parker JK. Bond length and reactivity. Structure of 3,5-bis(trifluoromethyl)benzyl 4-nitrobenzoate Acta Crystallographica Section C Crystal Structure Communications. 45: 237-239. DOI: 10.1107/S0108270188010145  0.327
1989 Kirby AJ, Percy JM. Intramolecular proton-transfer catalysis of nucleophilic catalysis of acetal hydrolysis. The hydrolysis of 8-dimethylamino-1-methoxymethoxynaphthalene Journal of the Chemical Society-Perkin Transactions 1. 907-912. DOI: 10.1039/P29890000907  0.435
1989 Blagoeva IB, Pojarlieff IG, Tashev DT, Kirby AJ. Intramolecular nucleophilic attack by urea nitrogen. Reactivity–selectivity relationships for the general acid–base catalysed cyclisations of ureido acids and esters Journal of the Chemical Society-Perkin Transactions 1. 347-353. DOI: 10.1039/P29890000347  0.464
1988 Amyes TL, Kirby AJ. Intramolecular nucleophilic addition of phenolate oxygen to double bonds activated by carboxyl and carboxylate groups. Relative reactivity, stereochemistry, and mechanism Journal of the American Chemical Society. 110: 6505-6514. DOI: 10.1021/Ja00227A035  0.404
1988 Kirby AJ, Percy JM. Exceptional reactivity of the aromatic ring in 8-substituted 1-naphthol derivatives. Ready reduction to tetralins Tetrahedron. 44: 6911-6919. DOI: 10.1016/S0040-4020(01)86221-9  0.312
1988 Kirby AJ, Percy JM. Synthesis of 8-substituted 1-naphthylamine derivatives. exceptional reactivity of the substituents. Tetrahedron. 44: 6903-6910. DOI: 10.1016/S0040-4020(01)86220-7  0.327
1987 Edwards MR, Kirby AJ, Raithby PR, Jones PG. Bond length and reactivity: the Beckmann rearrangement. 5. Structure of 4-phenylcyclohexanone oxime O-4-nitrobenzoate ester at 290 K Acta Crystallographica Section C Crystal Structure Communications. 43: 300-303. DOI: 10.1107/S0108270187096057  0.309
1987 Barber SE, Kirby AJ. Intramolecular proton transfer catalysis of ether hydrolysis Journal of the Chemical Society, Chemical Communications. 1775-1776. DOI: 10.1039/C39870001775  0.462
1987 Kirby AJ, Percy JM. The hydrogen bond as a key factor in efficient intramolecular proton transfer catalysis Journal of the Chemical Society, Chemical Communications. 1774-1775. DOI: 10.1039/C39870001774  0.388
1986 Jones PG, Sheldrick GM, Edwards MR, Kirby AJ. Bond length and reactivity: 1-arylethyl ethers and esters. 3. Structures of three trityl ethers of 1-arylethanols: 1-phenylethyl, 1-(4-chlorophenyl)ethyl and 1-(4-nitrophenyl)ethyl triphenylmethyl ethers Acta Crystallographica Section C Crystal Structure Communications. 42: 1361-1364. DOI: 10.1107/S0108270186092260  0.369
1986 Drummond JN, Kirby AJ. Intramolecular catalysis of sulphate diester hydrolysis by one and two carboxy groups. The hydrolysis of aryl 2-carboxyphenyl sulphates Journal of the Chemical Society-Perkin Transactions 1. 579-583. DOI: 10.1039/P29860000579  0.471
1986 Abell KW, Kirby AJ. Acceleration of P-O cleavage reactions of phosphate monoester dianions in dipolar aprotic solvents Tetrahedron Letters. 27: 1085-1088. DOI: 10.1016/S0040-4039(86)80055-7  0.374
1985 Jones PG, Sheldrick GM, Kirby AJ, Briggs AJ. Bond length and reactivity. Structure of 1-methoxymethoxy-3,5-dinitrobenzene, C8H8N2O6 Acta Crystallographica Section C Crystal Structure Communications. 41: 1377-1379. DOI: 10.1107/S0108270185007843  0.303
1985 WAGENAAR A, KIRBY AJ, ENGBERTS JBFN. ChemInform Abstract: ACID-CATALYZED HYDROLYSIS OF BENZENESULFONAMIDES. RATE ENHANCEMENTS BY ORTHO-ALKYL SUBSTITUENTS Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198551083  0.407
1985 Wagenaar A, Kirby AJ, Engberts JBFN. Intramolecularly Catalyzed Sulfonamide Hydrolysis. 8. Intramolecular Nucleophilic Catalysis By A Neighboring Hydroxyl Group In Acid-Catalyzed Benzenesulfonamide Hydrolysis Cheminform. 16. DOI: 10.1002/Chin.198509225  0.483
1984 Jones PG, Sheldrick GM, Kirby AJ, Abell KWY. Bis(cyclohexylammonium) propargyl phosphate dihydrate, 2C6H14N+.C3H3O4P2−.2H2O Acta Crystallographica Section C Crystal Structure Communications. 40: 547-549. DOI: 10.1107/S0108270184004819  0.304
1984 Jones PG, Sheldrick GM, Kirby AJ, Briggs AJ. 2-Methoxymethoxybenzoic acid, C9H10O4 Acta Crystallographica Section C Crystal Structure Communications. 40: 545-547. DOI: 10.1107/S0108270184004807  0.318
1984 Evans CM, Kirby AJ. Intramolecular nucleophilic addition of phenolate to unactivated double and triple bonds. Relative reactivity, regiospecificity, stereochemistry, and mechanism Journal of the Chemical Society, Perkin Transactions 2. 1269-1275. DOI: 10.1039/P29840001269  0.437
1984 Evans CM, Kirby AJ. A model for olefin hydration: Intramolecular nucleophilic addition of phenolate oxygen to the unactivated double bond Journal of the Chemical Society, Perkin Transactions 2. 1259-1267. DOI: 10.1039/P29840001259  0.452
1984 Blagoeva IB, Pojarlieff IG, Kirby AJ. Intramolecular nucleophilic attack on carboxylate by ureide anion. General acid–base catalysis of the alkaline cyclisation of 2,2,3,5-tetramethylhydantoic acid Journal of the Chemical Society-Perkin Transactions 1. 15: 745-751. DOI: 10.1039/P29840000745  0.478
1984 Wagenaar A, Kirby AJ, Engberts JBFN. Intramolecular-Catalyzed Sulfonamide Hydrolysis .8. Intramolecular Nucleophilic Catalysis By The Neighboring Hydroxyl Group In Acid-Catalyzed Benzenesulfonamide Hydrolysis Journal of Organic Chemistry. 49: 3445-3448. DOI: 10.1021/Jo00193A001  0.419
1984 Kirby AJ. Stereoelectronic effects on acetal hydrolysis Accounts of Chemical Research. 17: 305-311. DOI: 10.1021/Ar00105A002  0.349
1984 Jones PG, Kirby AJ. Simple correlation between bond length and reactivity. Combined use of crystallographic and kinetic data to explore a reaction coordinate Journal of the American Chemical Society. 106: 6207-6212. DOI: 10.1002/Chin.198506059  0.364
1984 Briggs AJ, Glenn R, Jones PG, Kirby AJ, Ramaswamy P. Bond length and reactivity. Stereoelectronic effects on bonding in acetals and glucosides Journal of the American Chemical Society. 106: 6200-6206. DOI: 10.1002/Chin.198506058  0.301
1984 Jager J, Graafland T, Schenk H, Kirby AJ, Engberts JBFN. Intramolecular-Catalyzed Sulfonamide Hydrolysis. Vii. The Thorpe-Ingold Effect In The Intramolecular Carboxyl-Catalyzed Hydrolysis Of Sulfonamides Cheminform. 15. DOI: 10.1002/Chin.198416151  0.319
1983 Briggs AJ, Evans CM, Glenn R, Kirby AJ. Stereoelectronic effects at oxygen. A very large effect on the hydrolysis of a conformationally locked acetal: Implications for β-glycosidase mechanisms Journal of the Chemical Society, Perkin Transactions 2. 1637-1640. DOI: 10.1039/P29830001637  0.343
1983 Kirby AJ, Martin RJ. Stereoelectronic effects on acetal cleavage. The separation of the π-donor and σ-acceptor properties of oxygen Journal of the Chemical Society-Perkin Transactions 1. 15: 1633-1636. DOI: 10.1039/P29830001633  0.363
1983 Kirby AJ, Martin RJ. Stereoelectronic control of the hydrolysis of a conformationally locked acetal Journal of the Chemical Society-Perkin Transactions 1. 15: 1627-1632. DOI: 10.1039/P29830001627  0.441
1983 Chandrasekhar S, Kirby AJ, Martin RJ. Stereoelectronic effects at oxygen. The hydrolysis of 2-aryloxy-trans-1-oxadecalins Journal of the Chemical Society-Perkin Transactions 1. 15: 1619-1626. DOI: 10.1039/P29830001619  0.375
1983 Abell KWY, Kirby AJ. Intramolecular general acid catalysis of intramolecular nucleophilic catalysis of the hydrolysis of a phosphate diester Journal of the Chemical Society-Perkin Transactions 1. 14: 1171-1174. DOI: 10.1039/P29830001171  0.466
1983 ABELL KWY, KIRBY AJ. ChemInform Abstract: INTRAMOLECULAR GENERAL ACID CATALYSIS OF INTRAMOLECULAR NUCLEOPHILIC CATALYSIS OF THE HYDROLYSIS OF A PHOSPHATE DIESTER Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198348140  0.345
1982 Jones PG, Kirby AJ. Evidence from crystal structures for an incipient fragmentation reaction Journal of the Chemical Society, Chemical Communications. 1365-1366. DOI: 10.1039/C39820001365  0.31
1981 Graafland T, Kirby AJ, Engberts JBFN. Intramolecular carboxyl-catalyzed hydrolysis of sulfonamides. 5. Salt effects on the intramolecular carboxyl-catalyzed hydrolysis of sulfonamides The Journal of Organic Chemistry. 46: 215-217. DOI: 10.1021/Jo00314A059  0.461
1981 Graafland T, Kirby AJ, Engberts JBFN. Intramolecular Carboxyl-Catalyzed Hydrolysis Of Sulfonamides. 5. Salt Effects S On The Intramolecular Carboxyl-Catalyzed Hydrolysis Of Sulfonamides Cheminform. 12. DOI: 10.1002/Chin.198124169  0.433
1980 Graafland T, Wagenaar A, Kirby A, Engberts J. Additions and Corrections - Structure and Reactivity in Intramolecular Catalysis. Catalysis of Sulfonamide Hydrolysis by the Neighboring Carboxyl Group Journal of the American Chemical Society. 102: 3663-3663. DOI: 10.1021/Ja00530A606  0.429
1980 Graafland T, Wagenaar A, Kirby AJ, Engberts JBFN. Structure And Reactivity In Intramolecular Catalysis. Catalysis Of Sulfonamide Hydrolysis By The Neighboring Carboxyl Group Cheminform. 11. DOI: 10.1002/Chin.198007173  0.362
1979 Camilleri P, Ellul R, Kirby AJ, Mujahid TG. The spontaneous formation of amides. The mechanism of lactam formation from 3-(2-aminophenyl)propionic acid Journal of the Chemical Society-Perkin Transactions 1. 11: 1617-1620. DOI: 10.1039/P29790001617  0.401
1979 Kirby AJ, Mujahid TG, Camilleri P. Anilide formation from an aliphatic ester. The mechanism of cyclisation of methyl 3-(2-aminophenyl)propionate Journal of the Chemical Society-Perkin Transactions 1. 11: 1610-1616. DOI: 10.1039/P29790001610  0.447
1979 Jones PG, Kirby AJ. Linear relationship between bond length and reactivity Journal of the Chemical Society, Chemical Communications. 288-289. DOI: 10.1039/C39790000288  0.349
1979 CAMILLERI P, CASSOLA A, KIRBY AJ, MUJAHID TG. ChemInform Abstract: NUCLEOPHILIC ATTACK BY AMINE NITROGEN ON THE IONIZED CARBOXY GROUP Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197904181  0.371
1978 Craze G, Kirby AJ, Osborne R. Bimolecular nucleophilic substitution on an acetal Journal of the Chemical Society-Perkin Transactions 1. 9: 357-368. DOI: 10.1039/P29780000357  0.455
1978 Camilleri P, Cassola A, Kirby AJ, Mujahid TG. Nucleophilic attack by amine nitrogen on the ionised carboxy group Journal of the Chemical Society, Chemical Communications. 807-808. DOI: 10.1039/C39780000807  0.43
1978 Kirby AJ, Martin RJ. Stereoelectronic control of acetal hydrolysis Journal of the Chemical Society, Chemical Communications. 803-804. DOI: 10.1039/C39780000803  0.346
1978 Kirby AJ, Mujahid TG. Intramolecular nucleophilic catalysis of amide hydrolysis by pyrimidine nitrogen Tetrahedron Letters. 19: 4081-4084. DOI: 10.1016/S0040-4039(01)95146-9  0.447
1976 Kirby AJ, Lloyd GJ. The E1cb mechanism for ester hydrolysis. Evidence for a dianion intermediate in the hydrolysis of aryl malonate anions Journal of the Chemical Society-Perkin Transactions 1. 8: 1762-1768. DOI: 10.1039/P29760001762  0.476
1976 Kirby AJ, Lloyd GJ. Structure and efficiency in intramolecular and enzymic catalysis: intramolecular general base catalysis. Hydrolysis of monoaryl malonates Journal of the Chemical Society-Perkin Transactions 1. 8: 1753-1761. DOI: 10.1039/P29760001753  0.413
1976 Kirby AJ, Lloyd GJ. Intramolecular general base catalysis in the hydrolysis of 3-dimethylaminopropionates Journal of the Chemical Society-Perkin Transactions 1. 8: 1748-1752. DOI: 10.1039/P29760001748  0.456
1975 WAGENAAR A, KIRBY AJ, ENGBERTS JBFN. ChemInform Abstract: INTRAMOLECULAR CATALYSIS OF SULFONAMIDE HYDROLYSIS BY A NEIGHBOURING CARBOXYL GROUP Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197503118  0.312
1974 Aldersley MF, Kirby AJ, Lancaster PW. Intramolecular displacement of alkoxide ions by the ionised carboxy-group: hydrolysis of alkyl hydrogen dialkylmaleates Journal of the Chemical Society-Perkin Transactions 1. 5: 1504-1510. DOI: 10.1039/P29740001504  0.48
1974 Kirby AJ, McDonald RS, Smith CR. Intramolecular catalysis of amide hydrolysis by two carboxy-groups Journal of the Chemical Society-Perkin Transactions 1. 5: 1495-1504. DOI: 10.1039/P29740001495  0.479
1974 Aldersley MF, Kirby AJ, Lancaster PW, McDonald RS, Smith CR. Intramolecular catalysis of amide hydrolysis by the carboxy-group. Rate determining proton transfer from external general acids in the hydrolysis of substituted maleamic acids Journal of the Chemical Society-Perkin Transactions 1. 5: 1487-1495. DOI: 10.1039/P29740001487  0.482
1974 Kirby AJ, Lloyd GJ. Intramolecular general base catalysis of intramolecular nucleophilic catalysis of ester hydrolysis Journal of the Chemical Society-Perkin Transactions 1. 5: 637-642. DOI: 10.1039/P29740000637  0.454
1974 Craze G, Kirby AJ. The role of the carboxy-group in intramolecular catalysis of acetal hydrolysis. The hydrolysis of substituted 2-methoxymethoxybenzoic acids Journal of the Chemical Society-Perkin Transactions 1. 5: 61-66. DOI: 10.1039/P29740000061  0.472
1974 Wagenaar A, Kirby A, Engberts JB. Intramolecular catalysis of sulfonamide hydrolysis by a neighbouring carboxyl group Tetrahedron Letters. 15: 3735-3738. DOI: 10.1016/S0040-4039(01)91994-X  0.425
1974 KIRBY AJ, MCDONALD RS, SMITH CR. ChemInform Abstract: INTRAMOLECULAR CATALYSIS OF AMIDE HYDROLYSIS BY TWO CARBOXY-GROUPS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197451194  0.302
1974 ALDERSLEY MF, KIRBY AJ, LANCASTER PW, MCDONALD RS, SMITH CR. ChemInform Abstract: INTRAMOLECULAR CATALYSIS OF AMIDE HYDROLYSIS BY THE CARBOXY-GROUP, RATE DETERMINING PROTON TRANSFER FROM EXTERNAL GENERAL ACIDS IN THE HYDROLYSIS OF SUBSTITUTED MALEAMIC ACIDS Chemischer Informationsdienst. 5. DOI: 10.1002/chin.197451193  0.335
1974 KIRBY AJ, LLOYD GJ. ChemInform Abstract: INTRAMOLECULAR GENERAL BASE CATALYSIS OF INTRAMOLECULAR NUCLEOPHILIC CATALYSIS OF ESTER HYDROLYSIS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197433184  0.321
1974 KIRBY AJ, LANCASTER PW, SMITH CR. ChemInform Abstract: STRUCTURE AND MECHANISM OF INTRAMOLECULAR CATALYSIS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197432114  0.322
1974 CRAZE G, KIRBY AJ. ChemInform Abstract: THE ROLE OF THE CARBOXY-GROUP IN INTRAMOLECULAR CATALYSIS OF ACETAL HYDROLYSIS, THE HYDROLYSIS OF SUBSTITUTED 2-METHOXYMETHOXYBENZOIC ACIDS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197412123  0.34
1972 Aldersley MF, Kirby AJ, Lancaster PW. Intramolecular displcement of methoxide by the ionised carboxy-group Journal of the Chemical Society, Chemical Communications. 834-835. DOI: 10.1039/C39720000834  0.438
1972 Aldersley MF, Kirby AJ, Lancaster PW. Rate-determining proton transfer in intramolecular catalysis of amide hydrolysis by the carboxylic acid group Journal of the Chemical Society, Chemical Communications. 570-571. DOI: 10.1039/C39720000570  0.414
1968 Fersht AR, Kirby AJ. Intramolecular nucleophilic catalysis in the hydrolysis of substituted aspirin acids. Journal of the American Chemical Society. 90: 5826-32. PMID 5679173  0.624
1968 Fersht AR, Kirby AJ. Intramolecular nucleophilic catalysis of ester hydrolysis by the ionized carboxyl group. The hydrolysis of 3,5-dinitroaspirin anion. Journal of the American Chemical Society. 90: 5818-26. PMID 5679172  0.654
1968 Fersht AR, Kirby AJ. Series nucleophilic catalysis in the hydrolysis of 3-acetoxyphthalate. Intramolecular catalysis of ester hydrolysis by the carboxyl group once removed Journal of the American Chemical Society. 90: 5833-5838. DOI: 10.1021/ja01023a030  0.361
1967 Fersht AR, Kirby AJ. The hydrolysis of aspirin. Intramolecular general base catalysis of ester hydrolysis. Journal of the American Chemical Society. 89: 4857-63. PMID 6074803 DOI: 10.1021/Ja00995A007  0.652
1967 Fersht AR, Kirby AJ. Structure and mechanism in intramolecular catalysis. The hydrolysis of substituted aspirins. Journal of the American Chemical Society. 89: 4853-6. PMID 6074802 DOI: 10.1021/Ja00995A006  0.632
1967 Fersht AR, Kirby AJ. Intramolecular general acid catalysis of ester hydrolysis by the carboxylic acid group Journal of the American Chemical Society. 89: 5961-5962. DOI: 10.1021/Ja00999A045  0.412
1967 Fersht AR, Kirby AJ. Intramolecular nucleophilic catalysis of ester hydrolysis by the carboxylate group Journal of the American Chemical Society. 89: 5960-5961. DOI: 10.1021/Ja00999A044  0.451
1967 Kirby AJ, Varvoglis AG. The Reactivity of Phosphate Esters. Monoester Hydrolysis Journal of the American Chemical Society. 89: 415-423. DOI: 10.1021/Ja00978A044  0.689
1966 Kirby AJ, Varvoglis AG. 2,4-Dinitrophenyl Phosphate Journal of the American Chemical Society. 88: 1823-1824. DOI: 10.1021/Ja00960A048  0.631
1965 Kirby AJ, Jencks WP. Base Catalysis of the Reaction of Secondary Amines with p-Nitrophenyl Phosphate. Kinetic Evidence for an Addition Intermediate in Nucleophilic Aromatic Substitution1 Journal of the American Chemical Society. 87: 3217-3224. DOI: 10.1021/ja01092a037  0.649
1965 Kirby AJ, Jencks WP. The Reactivity of Nucleophilic Reagents toward the p-Nitrophenyl Phosphate Dianion1 Journal of the American Chemical Society. 87: 3209-3216. DOI: 10.1021/ja01092a036  0.596
Show low-probability matches.