| Year |
Citation |
Score |
| 2024 |
Wu D, Yang J, Liu C, Hsieh TC, Marchi E, Blair J, Krawitz P, Weng C, Chung W, Lyon GJ, Krantz ID, Kalish JM, Wang K. GestaltMML: Enhancing Rare Genetic Disease Diagnosis through Multimodal Machine Learning Combining Facial Images and Clinical Texts. Arxiv. PMID 38711434 |
0.304 |
|
| 2023 |
Belbachir N, Wu Y, Shen M, Zhang SL, Zhang JZ, Liu C, Knollmann BC, Lyon GJ, Ma N, Wu JC. Studying Long QT Syndrome Caused by Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells. Circulation. 148: 1598-1601. PMID 37956223 DOI: 10.1161/CIRCULATIONAHA.122.061864 |
0.658 |
|
| 2023 |
Kleyner R, Ung N, Mohammad A, Marchi E, Amble K, Gavin M, Madrid R, Lyon G. ITPR1-Associated Spinocerebellar Ataxia with Craniofacial Features - Additional Evidence for Germline Mosaicism. Cold Spring Harbor Molecular Case Studies. PMID 37821226 DOI: 10.1101/mcs.a006303 |
0.816 |
|
| 2023 |
Dingemans AJM, Hinne M, Truijen KMG, Goltstein L, van Reeuwijk J, de Leeuw N, Schuurs-Hoeijmakers J, Pfundt R, Diets IJ, den Hoed J, de Boer E, Coenen-van der Spek J, Jansen S, van Bon BW, Jonis N, ... ... Lyon GJ, et al. PhenoScore quantifies phenotypic variation for rare genetic diseases by combining facial analysis with other clinical features using a machine-learning framework. Nature Genetics. PMID 37550531 DOI: 10.1038/s41588-023-01469-w |
0.328 |
|
| 2023 |
Kierzkowska O, Sarino K, Carter D, Guo L, Marchi E, Voronova A, Lyon GJ. Documentation and prevalence of prenatal and neonatal outcomes in a cohort of individuals with KBG syndrome. American Journal of Medical Genetics. Part A. PMID 37226940 DOI: 10.1002/ajmg.a.63311 |
0.303 |
|
| 2023 |
Lyon GJ, Vedaie M, Beisheim T, Park A, Marchi E, Gottlieb L, Hsieh TC, Klinkhammer H, Sandomirsky K, Cheng H, Starr LJ, Preddy I, Tseng M, Li Q, Hu Y, et al. Expanding the phenotypic spectrum of NAA10-related neurodevelopmental syndrome and NAA15-related neurodevelopmental syndrome. European Journal of Human Genetics : Ejhg. PMID 37130971 DOI: 10.1038/s41431-023-01368-y |
0.355 |
|
| 2022 |
Guo L, Park J, Yi E, Marchi E, Hsieh TC, Kibalnyk Y, Moreno-Sáez Y, Biskup S, Puk O, Beger C, Li Q, Wang K, Voronova A, Krawitz PM, Lyon GJ. KBG syndrome: videoconferencing and use of artificial intelligence driven facial phenotyping in 25 new patients. European Journal of Human Genetics : Ejhg. PMID 35970914 DOI: 10.1038/s41431-022-01171-1 |
0.365 |
|
| 2022 |
Danis D, Jacobsen JOB, Balachandran P, Zhu Q, Yilmaz F, Reese J, Haimel M, Lyon GJ, Helbig I, Mungall CJ, Beck CR, Lee C, Smedley D, Robinson PN. SvAnna: efficient and accurate pathogenicity prediction of coding and regulatory structural variants in long-read genome sequencing. Genome Medicine. 14: 44. PMID 35484572 DOI: 10.1186/s13073-022-01046-6 |
0.319 |
|
| 2021 |
Kleyner R, Mohammad A, Marchi E, Horowitz N, Haworth A, King B, Amble K, Gavin M, Velinov M, Lyon GJ. Autosomal recessive SLC30A9 variants in a Proband with a Cerebro-Renal Syndrome and No Parental Consanguinity. Cold Spring Harbor Molecular Case Studies. PMID 34716203 DOI: 10.1101/mcs.a006137 |
0.785 |
|
| 2021 |
Kweon HY, Lee MN, Dorfel M, Seo S, Gottlieb L, PaPazyan T, McTiernan N, Ree R, Bolton D, Garcia A, Flory M, Crain J, Sebold A, Lyons S, Ismail A, ... ... Lyon GJ, et al. compensates for in mice in the amino-terminal acetylation pathway. Elife. 10. PMID 34355692 DOI: 10.7554/eLife.65952 |
0.714 |
|
| 2021 |
Tsetsos F, Yu D, Sul JH, Huang AY, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau GA, Aschauer H, Stamenkovic M, ... ... Lyon GJ, ... ... Lyon GJ, ... ... Lyon GJ, et al. Synaptic processes and immune-related pathways implicated in Tourette syndrome. Translational Psychiatry. 11: 56. PMID 33462189 DOI: 10.1038/s41398-020-01082-z |
0.533 |
|
| 2020 |
Cheng H, Gottlieb L, Marchi E, Kleyner R, Bhardwaj P, Rope AF, Rosenheck S, Moutton S, Philippe C, Eyaid W, Alkuraya FS, Toribio J, Mena R, Prada CE, Stessman H, ... ... Lyon GJ, et al. Phenotypic and biochemical analysis of an international cohort of individuals with variants in NAA10 and NAA15. Human Molecular Genetics. PMID 32027362 DOI: 10.1093/Hmg/Ddz173 |
0.821 |
|
| 2019 |
Cheng H, Capponi S, Wakeling E, Marchi E, Li Q, Zhao M, Weng C, Stefan PG, Ahlfors H, Kleyner R, Rope A, Lumaka A, Lukusa P, Devriendt K, Vermeesch J, ... ... Lyon GJ, et al. Missense variants in TAF1 and developmental phenotypes: challenges of determining pathogenicity. Human Mutation. PMID 31646703 DOI: 10.1002/Humu.23936 |
0.821 |
|
| 2019 |
Nellåker C, Alkuraya FS, Baynam G, Bernier RA, Bernier FPJ, Boulanger V, Brudno M, Brunner HG, Clayton-Smith J, Cogné B, Dawkins HJS, deVries BBA, Douzgou S, Dudding-Byth T, Eichler EE, ... ... Lyon GJ, et al. Enabling Global Clinical Collaborations on Identifiable Patient Data: The Minerva Initiative. Frontiers in Genetics. 10: 611. PMID 31417602 DOI: 10.3389/Fgene.2019.00611 |
0.359 |
|
| 2019 |
Paine I, Posey JE, Grochowski CM, Jhangiani SN, Rosenheck S, Kleyner R, Marmorale T, Yoon M, Wang K, Robison R, Cappuccio G, Pinelli M, Magli A, Coban Akdemir Z, Hui J, ... ... Lyon GJ, et al. Paralog Studies Augment Gene Discovery: DDX and DHX Genes. American Journal of Human Genetics. PMID 31256877 DOI: 10.1016/J.Ajhg.2019.06.001 |
0.804 |
|
| 2019 |
Hsieh TC, Mensah MA, Pantel JT, Aguilar D, Bar O, Bayat A, Becerra-Solano L, Bentzen HB, Biskup S, Borisov O, Braaten O, Ciaccio C, Coutelier M, Cremer K, Danyel M, ... ... Lyon GJ, et al. PEDIA: prioritization of exome data by image analysis. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 31164752 DOI: 10.1038/S41436-019-0566-2 |
0.379 |
|
| 2019 |
Cheng H, Gottlieb L, Marchi E, Kleyner R, Bhardwaj P, Rope AF, Rosenheck S, Moutton S, Philippe C, Eyaid W, Alkuraya FS, Toribio J, Mena R, Prada CE, Stessman H, ... ... Lyon GJ, et al. Phenotypic and biochemical analysis of an international cohort of individuals with variants in NAA10 and NAA15. Human Molecular Genetics. PMID 31127942 DOI: 10.1093/hmg/ddz111 |
0.823 |
|
| 2019 |
Kline AD, Krantz ID, Bando M, Shirahige K, Chea S, Sakata T, Rao S, Dorsett D, Singh VP, Gerton JL, Horsfield JA, Calof AL, Katz O, Grados M, Raible S, ... ... Lyon G, et al. Cornelia de Lange syndrome, related disorders, and the Cohesin complex: Abstracts from the 8th biennial scientific and educational symposium 2018. American Journal of Medical Genetics. Part A. PMID 30874362 DOI: 10.1002/Ajmg.A.61108 |
0.408 |
|
| 2019 |
Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, ... ... Lyon GJ, et al. Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. The American Journal of Psychiatry. 176: 217-227. PMID 30818990 DOI: 10.1176/Appi.Ajp.2018.18070857 |
0.588 |
|
| 2018 |
Wu Y, Lyon GJ. NAA10-related syndrome. Experimental & Molecular Medicine. 50: 85. PMID 30054457 DOI: 10.1038/S12276-018-0098-X |
0.724 |
|
| 2018 |
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Lyon GJ, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757 |
0.339 |
|
| 2018 |
Cheng H, Dharmadhikari AV, Varland S, Ma N, Domingo D, Kleyner R, Rope AF, Yoon M, Stray-Pedersen A, Posey JE, Crews SR, Eldomery MK, Akdemir ZC, Lewis AM, Sutton VR, ... ... Lyon GJ, et al. Truncating Variants in NAA15 Are Associated with Variable Levels of Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies. American Journal of Human Genetics. PMID 29656860 DOI: 10.1016/J.Ajhg.2018.03.004 |
0.822 |
|
| 2018 |
Fang H, Huang YF, Radhakrishnan A, Siepel A, Lyon GJ, Schatz MC. Scikit-ribo Enables Accurate Estimation and Robust Modeling of Translation Dynamics at Codon Resolution. Cell Systems. PMID 29361467 DOI: 10.1016/J.Cels.2017.12.007 |
0.529 |
|
| 2017 |
Greenberg E, Tung ES, Gauvin C, Osiecki L, Yang KG, Curley E, Essa A, Illmann C, Sandor P, Dion Y, Lyon GJ, King RA, Darrow S, Hirschtritt ME, Budman CL, et al. Prevalence and predictors of hair pulling disorder and excoriation disorder in Tourette syndrome. European Child & Adolescent Psychiatry. PMID 29098466 DOI: 10.1007/S00787-017-1074-Z |
0.339 |
|
| 2017 |
Hirschtritt ME, Darrow SM, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King RA, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, et al. Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome. Psychological Medicine. 1-15. PMID 28651666 DOI: 10.1017/S0033291717001672 |
0.322 |
|
| 2017 |
Huang AY, Yu D, Davis LK, Sul JH, Tsetsos F, Ramensky V, Zelaya I, Ramos EM, Osiecki L, Chen JA, McGrath LM, Illmann C, Sandor P, Barr CL, Grados M, ... ... Lyon GJ, et al. Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron. 94: 1101-1111.e7. PMID 28641109 DOI: 10.1016/J.Neuron.2017.06.010 |
0.391 |
|
| 2017 |
Fang H, Wu Y, Yang H, Yoon M, Jiménez-Barrón LT, Mittelman D, Robison R, Wang K, Lyon GJ. Whole genome sequencing of one complex pedigree illustrates challenges with genomic medicine. Bmc Medical Genomics. 10: 10. PMID 28228131 DOI: 10.1186/S12920-017-0246-5 |
0.801 |
|
| 2016 |
Kleyner R, Malcolmson J, Tegay D, Ward K, Maughan A, Maughan G, Nelson L, Wang K, Robison R, Lyon GJ. KBG syndrome involving a single-nucleotide duplication in ANKRD11. Cold Spring Harbor Molecular Case Studies. 2: a001131. PMID 27900361 DOI: 10.1101/mcs.a001131 |
0.81 |
|
| 2016 |
Malcolmson J, Kleyner R, Tegay D, Adams W, Ward K, Coppinger J, Nelson L, Meisler MH, Wang K, Robison R, Lyon GJ. SCN8A mutation in a child presenting with seizures and developmental delays. Cold Spring Harbor Molecular Case Studies. 2: a001073. PMID 27900360 DOI: 10.1101/mcs.a001073 |
0.788 |
|
| 2016 |
Köhler S, Vasilevsky NA, Engelstad M, Foster E, McMurry J, Aymé S, Baynam G, Bello SM, Boerkoel CF, Boycott KM, Brudno M, Buske OJ, Chinnery PF, Cipriani V, Connell LE, ... ... Lyon GJ, et al. The Human Phenotype Ontology in 2017. Nucleic Acids Research. PMID 27899602 DOI: 10.1093/Nar/Gkw1039 |
0.399 |
|
| 2016 |
Fang H, Bergmann EA, Arora K, Vacic V, Zody MC, Iossifov I, O'Rawe JA, Wu Y, Jimenez Barron LT, Rosenbaum J, Ronemus M, Lee YH, Wang Z, Dikoglu E, Jobanputra V, ... Lyon GJ, et al. Indel variant analysis of short-read sequencing data with Scalpel. Nature Protocols. 11: 2529-2548. PMID 27854363 DOI: 10.1038/Nprot.2016.150 |
0.756 |
|
| 2016 |
Darrow SM, Hirschtritt ME, Davis LK, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, et al. Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome. The American Journal of Psychiatry. appiajp201616020240. PMID 27809572 DOI: 10.1176/Appi.Ajp.2016.16020240 |
0.349 |
|
| 2016 |
Dörfel MJ, Fang H, Crain J, Klingener M, Weiser J, Lyon GJ. Proteomic and genomic characterization of a yeast model for Ogden syndrome. Yeast (Chichester, England). PMID 27668839 DOI: 10.1002/Yea.3211 |
0.805 |
|
| 2016 |
Hirschtritt ME, Darrow SM, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King RA, Pauls DL, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, et al. Social disinhibition is a heritable subphenotype of tics in Tourette syndrome. Neurology. PMID 27371487 DOI: 10.1212/Wnl.0000000000002910 |
0.309 |
|
| 2016 |
Shi L, Guo Y, Dong C, Huddleston J, Yang H, Han X, Fu A, Li Q, Li N, Gong S, Lintner KE, Ding Q, Wang Z, Hu J, Wang D, ... ... Lyon GJ, et al. Long-read sequencing and de novo assembly of a Chinese genome. Nature Communications. 7: 12065. PMID 27356984 DOI: 10.1038/Ncomms12065 |
0.42 |
|
| 2016 |
Desai A, Connolly JJ, March M, Hou C, Chiavacci R, Kim C, Lyon G, Hadley D, Hakonarson H. Systematic data-querying of large pediatric biorepository identifies novel Ehlers-Danlos Syndrome variant. Bmc Musculoskeletal Disorders. 17: 80. PMID 26879370 DOI: 10.1186/S12891-016-0936-8 |
0.401 |
|
| 2016 |
Klimas A, Wu Y, Ambrosi CM, Yu J, Williams JC, Bien H, Lyon GJ, Entcheva E. Disease Modeling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Using High-Throughput All-Optical Dynamic Cardiac Electrophysiology Frontiers in Optics. DOI: 10.1364/Fio.2016.Ff3A.3 |
0.653 |
|
| 2015 |
Jiménez-Barrón LT, O'Rawe JA, Wu Y, Yoon M, Fang H, Iossifov I, Lyon GJ. Genome-wide variant analysis of simplex autism families with an integrative clinical-bioinformatics pipeline. Cold Spring Harbor Molecular Case Studies. 1: a000422. PMID 27148569 DOI: 10.1101/mcs.a000422 |
0.81 |
|
| 2015 |
O'Rawe JA, Wu Y, Dörfel MJ, Rope AF, Au PY, Parboosingh JS, Moon S, Kousi M, Kosma K, Smith CS, Tzetis M, Schuette JL, Hufnagel RB, Prada CE, Martinez F, ... ... Lyon GJ, et al. TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations. American Journal of Human Genetics. 97: 922-32. PMID 26637982 DOI: 10.1016/J.Ajhg.2015.11.005 |
0.775 |
|
| 2015 |
Guo Y, Ding X, Shen Y, Lyon GJ, Wang K. SeqMule: automated pipeline for analysis of human exome/genome sequencing data. Scientific Reports. 5: 14283. PMID 26381817 DOI: 10.1038/Srep14283 |
0.416 |
|
| 2015 |
Dörfel MJ, Lyon GJ. The biological functions of Naa10 - From amino-terminal acetylation to human disease. Gene. 567: 103-131. PMID 25987439 DOI: 10.1016/J.Gene.2015.04.085 |
0.31 |
|
| 2015 |
Hirschtritt ME, Lee PC, Pauls DL, Dion Y, Grados MA, Illmann C, King RA, Sandor P, McMahon WM, Lyon GJ, Cath DC, Kurlan R, Robertson MM, Osiecki L, Scharf JM, et al. Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome. Jama Psychiatry. 72: 325-33. PMID 25671412 DOI: 10.1001/Jamapsychiatry.2014.2650 |
0.315 |
|
| 2015 |
He M, Person TN, Hebbring SJ, Heinzen E, Ye Z, Schrodi SJ, McPherson EW, Lin SM, Peissig PL, Brilliant MH, O'Rawe J, Robison RJ, Lyon GJ, Wang K. SeqHBase: a big data toolset for family based sequencing data analysis. Journal of Medical Genetics. 52: 282-8. PMID 25587064 DOI: 10.1136/Jmedgenet-2014-102907 |
0.812 |
|
| 2015 |
O'Rawe JA, Ferson S, Lyon GJ. Accounting for uncertainty in DNA sequencing data. Trends in Genetics : Tig. 31: 61-6. PMID 25579994 DOI: 10.1016/J.Tig.2014.12.002 |
0.771 |
|
| 2015 |
Myklebust LM, Van Damme P, Støve SI, Dörfel MJ, Abboud A, Kalvik TV, Grauffel C, Jonckheere V, Wu Y, Swensen J, Kaasa H, Liszczak G, Marmorstein R, Reuter N, Lyon GJ, et al. Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Human Molecular Genetics. 24: 1956-76. PMID 25489052 DOI: 10.1093/Hmg/Ddu611 |
0.73 |
|
| 2014 |
Fang H, Wu Y, Narzisi G, O'Rawe JA, Barrón LT, Rosenbaum J, Ronemus M, Iossifov I, Schatz MC, Lyon GJ. Reducing INDEL calling errors in whole genome and exome sequencing data. Genome Medicine. 6: 89. PMID 25426171 DOI: 10.1186/S13073-014-0089-Z |
0.785 |
|
| 2014 |
Narzisi G, O'Rawe JA, Iossifov I, Fang H, Lee YH, Wang Z, Wu Y, Lyon GJ, Wigler M, Schatz MC. Accurate de novo and transmitted indel detection in exome-capture data using microassembly. Nature Methods. 11: 1033-6. PMID 25128977 DOI: 10.1038/Nmeth.3069 |
0.774 |
|
| 2014 |
McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, ... ... Lyon GJ, et al. Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 910-9. PMID 25062598 DOI: 10.1016/J.Jaac.2014.04.022 |
0.397 |
|
| 2014 |
Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, ... ... Lyon GJ, et al. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biology. 15: R53. PMID 24667040 DOI: 10.1186/Gb-2014-15-3-R53 |
0.447 |
|
| 2014 |
Barash CI, Lyon G. Open access and data sharing: Easier said than done Applied and Translational Genomics. 3: 120-121. DOI: 10.1016/J.Atg.2014.09.008 |
0.378 |
|
| 2013 |
Lyon GJ, Segal JP. Practical, ethical and regulatory considerations for the evolving medical and research genomics landscape. Applied & Translational Genomics. 2: 34-40. PMID 27942444 DOI: 10.1016/J.Atg.2013.02.001 |
0.359 |
|
| 2013 |
O'Rawe JA, Fang H, Rynearson S, Robison R, Kiruluta ES, Higgins G, Eilbeck K, Reese MG, Lyon GJ. Integrating precision medicine in the study and clinical treatment of a severely mentally ill person. Peerj. 1: e177. PMID 24109560 DOI: 10.7717/Peerj.177 |
0.798 |
|
| 2013 |
Wang K, Kim C, Bradfield J, Guo Y, Toskala E, Otieno FG, Hou C, Thomas K, Cardinale C, Lyon GJ, Golhar R, Hakonarson H. Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement. Genome Medicine. 5: 67. PMID 23889995 DOI: 10.1186/Gm471 |
0.484 |
|
| 2013 |
Shi L, Zhang X, Golhar R, Otieno FG, He M, Hou C, Kim C, Keating B, Lyon GJ, Wang K, Hakonarson H. Whole-genome sequencing in an autism multiplex family. Molecular Autism. 4: 8. PMID 23597238 DOI: 10.1186/2040-2392-4-8 |
0.499 |
|
| 2013 |
O'Rawe J, Jiang T, Sun G, Wu Y, Wang W, Hu J, Bodily P, Tian L, Hakonarson H, Johnson WE, Wei Z, Wang K, Lyon GJ. Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing. Genome Medicine. 5: 28. PMID 23537139 DOI: 10.1186/Gm432 |
0.807 |
|
| 2013 |
Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, ... ... Lyon GJ, et al. Genome-wide association study of Tourette's syndrome. Molecular Psychiatry. 18: 721-8. PMID 22889924 DOI: 10.1038/Mp.2012.69 |
0.426 |
|
| 2012 |
Lyon GJ, Wang K. Identifying disease mutations in genomic medicine settings: current challenges and how to accelerate progress. Genome Medicine. 4: 58. PMID 22830651 DOI: 10.1186/Gm359 |
0.455 |
|
| 2012 |
Elia J, Glessner JT, Wang K, Takahashi N, Shtir CJ, Hadley D, Sleiman PM, Zhang H, Kim CE, Robison R, Lyon GJ, Flory JH, Bradfield JP, Imielinski M, Hou C, et al. Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature Genetics. 44: 78-84. PMID 22138692 DOI: 10.1038/Ng.1013 |
0.35 |
|
| 2012 |
Badner JA, Koller D, Foroud T, Edenberg H, Nurnberger JI, Zandi PP, Willour VL, McMahon FJ, Potash JB, Hamshere M, Grozeva D, Green E, Kirov G, Jones I, Jones L, ... ... Lyon GJ, et al. Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. Molecular Psychiatry. 17: 818-26. PMID 21769101 DOI: 10.1038/Mp.2011.89 |
0.402 |
|
| 2012 |
Lyon G, Jiang T, Wijk RV, Wang W, Bodily P, Xing J, Tian L, Robison R, Clement M, Yang L, Zhang P, Liu Y, Moore B, Solinge Wv, Yandell M, et al. Whole exome sequencing reveals the genetic basis of a case of idiopathic hemolytic anemia and suggests candidate rare variants for ADHD in a Utah pedigree F1000research. 3. DOI: 10.7490/F1000Research.1089758.1 |
0.377 |
|
| 2012 |
Rope AF, Wang K, Evjenth R, Xing J, Johnston JJ, Swensen JJ, Johnson WE, Moore B, Huff CD, Bird LM, Carey JC, Opitz JM, Stevens CA, Schank C, Jiang T, ... ... Lyon GJ, et al. Using VAAST and massively parallel sequencing to characterize a novel disorder caused by protein N-terminal acetyltransferase deficiency F1000research. 3. DOI: 10.7490/F1000Research.1089750.1 |
0.379 |
|
| 2012 |
Scharf J, Yu D, Mathews C, Neale B, Stewart E, Fagerness J, Evans P, Gamazon E, Service S, Osiecki L, Illmann C, Cath D, King R, Dion Y, Sandor P, ... ... Lyon G, et al. Genome-Wide Association Study of Gilles de la Tourette Syndrome (IN10-1.002) Neurology. 78: IN10-1.002-IN10-1.00. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In10-1.002 |
0.362 |
|
| 2011 |
Lyon GJ. Personal account of the discovery of a new disease using next-generation sequencing. Interview by Natalie Harrison. Pharmacogenomics. 12: 1519-23. PMID 22044413 DOI: 10.2217/Pgs.11.117 |
0.329 |
|
| 2011 |
Wei Z, Wang W, Hu P, Lyon GJ, Hakonarson H. SNVer: a statistical tool for variant calling in analysis of pooled or individual next-generation sequencing data. Nucleic Acids Research. 39: e132. PMID 21813454 DOI: 10.1093/Nar/Gkr599 |
0.414 |
|
| 2011 |
Lyon GJ, Jiang T, Van Wijk R, Wang W, Bodily PM, Xing J, Tian L, Robison RJ, Clement M, Lin Y, Zhang P, Liu Y, Moore B, Glessner JT, Elia J, et al. Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Discovery Medicine. 12: 41-55. PMID 21794208 |
0.358 |
|
| 2011 |
Rope AF, Wang K, Evjenth R, Xing J, Johnston JJ, Swensen JJ, Johnson WE, Moore B, Huff CD, Bird LM, Carey JC, Opitz JM, Stevens CA, Jiang T, Schank C, ... ... Lyon GJ, et al. Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. American Journal of Human Genetics. 89: 28-43. PMID 21700266 DOI: 10.1016/J.Ajhg.2011.05.017 |
0.456 |
|
| 2011 |
Rope AF, Wang K, Evjenth R, Xing J, Johnston JJ, Swensen JJ, Johnson W, Moore B, Huff CD, Bird LM, Carey JC, Opitz JM, Stevens CA, Schank C, Fain H, ... ... Lyon GJ, et al. Massively parallel sequencing identifies a previously unrecognized X-linked disorder resulting in lethality in male infants owing to amino-terminal acetyltransferase deficiency Genome Biology. 12: P13. DOI: 10.1186/Gb-2011-12-S1-P13 |
0.348 |
|
| 2010 |
Lyon GJ, Shprecher D, Coffey B, Kurlan R. Tourette's Disorder. Current Treatment Options in Neurology. 12: 274-86. PMID 20842587 DOI: 10.1007/S11940-010-0073-X |
0.522 |
|
| 2010 |
Lyon GJ, Samar SM, Conelea C, Trujillo MR, Lipinski CM, Bauer CC, Brandt BC, Kemp JJ, Lawrence ZE, Howard J, Castellanos FX, Woods D, Coffey BJ. Testing tic suppression: comparing the effects of dexmethylphenidate to no medication in children and adolescents with attention-deficit/hyperactivity disorder and Tourette's disorder. Journal of Child and Adolescent Psychopharmacology. 20: 283-9. PMID 20807066 DOI: 10.1089/Cap.2010.0032 |
0.498 |
|
| 2009 |
Lyon GJ, Samar S, Jummani R, Hirsch S, Spirgel A, Goldman R, Coffey BJ. Aripiprazole in children and adolescents with Tourette's disorder: an open-label safety and tolerability study. Journal of Child and Adolescent Psychopharmacology. 19: 623-33. PMID 20035580 DOI: 10.1089/Cap.2009.0035 |
0.498 |
|
| 2009 |
Lyon GJ, Coffey BJ. Complex tics and complex management in a case of severe Tourette's disorder (TD) in an adolescent. Journal of Child and Adolescent Psychopharmacology. 19: 469-74. PMID 19702501 DOI: 10.1089/Cap.2009.19402 |
0.503 |
|
| 2008 |
Lyon GJ, Coffey B, Silva R. Postraumatic stress disorder and reactive attachment disorder: outcome in an adolescent. Journal of Child and Adolescent Psychopharmacology. 18: 641-6. PMID 19108670 DOI: 10.1089/Cap.2008.1863 |
0.485 |
|
| 2008 |
Lyon GJ, Coffey B. Treating Tourette Syndrome and Tic Disorders: A Guide for Practitioners Journal of Child and Adolescent Psychopharmacology. 18: 411-412. DOI: 10.1089/Cap.2008.1849 |
0.536 |
|
| 2004 |
Wright JS, Lyon GJ, George EA, Muir TW, Novick RP. Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing. Proceedings of the National Academy of Sciences of the United States of America. 101: 16168-73. PMID 15528279 DOI: 10.1073/Pnas.0404039101 |
0.605 |
|
| 2004 |
Lyon GJ, Novick RP. Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides. 25: 1389-403. PMID 15374643 DOI: 10.1016/J.Peptides.2003.11.026 |
0.461 |
|
| 2003 |
Lyon GJ, Muir TW. Chemical signaling among bacteria and its inhibition. Chemistry & Biology. 10: 1007-21. PMID 14652068 DOI: 10.1016/J.Chembiol.2003.11.003 |
0.482 |
|
| 2003 |
Miller JS, Dudkin VY, Lyon GJ, Muir TW, Danishefsky SJ. Toward fully synthetic N-linked glycoproteins. Angewandte Chemie (International Ed. in English). 42: 431-4. PMID 12569509 DOI: 10.1002/Anie.200390131 |
0.479 |
|
| 2002 |
Lyon GJ, Wright JS, Muir TW, Novick RP. Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus. Biochemistry. 41: 10095-104. PMID 12146974 DOI: 10.1021/Bi026049U |
0.622 |
|
| 2002 |
Lyon GJ, Wright JS, Christopoulos A, Novick RP, Muir TW. Reversible and specific extracellular antagonism of receptor-histidine kinase signaling. The Journal of Biological Chemistry. 277: 6247-53. PMID 11733525 DOI: 10.1074/Jbc.M109989200 |
0.607 |
|
| 2000 |
Lyon GJ, Mayville P, Muir TW, Novick RP. Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC. Proceedings of the National Academy of Sciences of the United States of America. 97: 13330-5. PMID 11087872 DOI: 10.1073/Pnas.97.24.13330 |
0.609 |
|
| 2000 |
Jarraud S, Lyon GJ, Figueiredo AM, Lina G, Gérard L, Vandenesch F, Etienne J, Muir TW, Novick RP. Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus. Journal of Bacteriology. 182: 6517-22. PMID 11053400 DOI: 10.1128/Jb.182.22.6517-6522.2000 |
0.605 |
|
| 1999 |
Hernández A, Lyon GJ, Schneider MJ, St Germain DL. Isolation and characterization of the mouse gene for the type 3 iodothyronine deiodinase. Endocrinology. 140: 124-30. PMID 9886816 DOI: 10.1210/Endo.140.1.6423 |
0.336 |
|
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