Elizabeth Fisher - Publications

Affiliations: 
University of California, Berkeley, Berkeley, CA, United States 

0/279 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2024 Milioto C, Carcolé M, Giblin A, Coneys R, Attrebi O, Ahmed M, Harris SS, Lee BI, Yang M, Ellingford RA, Nirujogi RS, Biggs D, Salomonsson S, Zanovello M, de Oliveira P, ... ... Fisher EMC, et al. PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons. Nature Neuroscience. PMID 38424324 DOI: 10.1038/s41593-024-01589-4  0.01
2024 Godoy-Corchuelo JM, Ali Z, Brito Armas JM, Martins-Bach AB, García-Toledo I, Fernández-Beltrán LC, López-Carbonero JI, Bascuñana P, Spring S, Jimenez-Coca I, Muñoz de Bustillo Alfaro RA, Sánchez-Barrena MJ, Nair RR, Nieman BJ, Lerch JP, ... ... Fisher EMC, et al. TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43. Neurobiology of Disease. 106437. PMID 38367882 DOI: 10.1016/j.nbd.2024.106437  0.01
2024 Serrano ME, Kim E, Siow B, Ma D, Rojo L, Simmons C, Hayward D, Gibbins D, Singh N, Strydom A, Fisher EMC, Tybulewicz VLJ, Cash D. Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome. Neurobiology of Disease. 188: 106336. PMID 38317803 DOI: 10.1016/j.nbd.2023.106336  0.01
2024 Lana-Elola E, Aoidi R, Llorian M, Gibbins D, Buechsenschuetz C, Bussi C, Flynn H, Gilmore T, Watson-Scales S, Haugsten Hansen M, Hayward D, Song OR, Brault V, Herault Y, Deau E, ... ... Fisher EMC, et al. Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science Translational Medicine. 16: eadd6883. PMID 38266108 DOI: 10.1126/scitranslmed.add6883  0.01
2023 Wilkins OG, Chien MZYJ, Wlaschin JJ, Pisliakova M, Thompson D, Digby H, Simkin RL, Diaz JA, Mehta PR, Keuss MJ, Zanovello M, Brown AL, Harley P, Darbey A, Karda R, ... Fisher EMC, et al. Creation of de novo cryptic splicing for ALS/FTD precision medicine. Biorxiv : the Preprint Server For Biology. PMID 38014203 DOI: 10.1101/2023.11.15.565967  0.01
2023 Ontaneda D, Gulani V, Deshmane A, Shah A, Guruprakash DK, Jiang Y, Ma D, Fisher E, Rudick RA, Raza P, Kilbane M, Cohen JA, Sakaie K, Lowe MJ, Griswold MA, et al. Magnetic resonance fingerprinting in multiple sclerosis. Multiple Sclerosis and Related Disorders. 79: 105024. PMID 37783196 DOI: 10.1016/j.msard.2023.105024  0.01
2023 Muza PM, Pérez M, Noy S, Kurosawa M, Katsouri L, Tybulewicz VLJ, Fisher EMC, West SJ. Affordable optical clearing and immunolabelling in mouse brain slices. Bmc Research Notes. 16: 246. PMID 37777793 DOI: 10.1186/s13104-023-06511-y  0.01
2023 Ali Z, Godoy-Corchuelo JM, Martins-Bach AB, Garcia-Toledo I, Fernández-Beltrán LC, Nair RR, Spring S, Nieman BJ, Jimenez-Coca I, Bains RS, Forrest H, Lerch JP, Miller K, Fisher EMC, Cunningham TJ, et al. FUS-NLS mutation causes neurodevelopmental and systemic metabolic alterations. Disease Models & Mechanisms. PMID 37772684 DOI: 10.1242/dmm.050200  0.01
2023 Loomis SJ, Sadhu N, Fisher E, Gafson AR, Huang Y, Yang C, Hughes EE, Marshall E, Herman A, John S, Runz H, Jia X, Bhangale T, Bronson PG. Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials. Scientific Reports. 13: 14313. PMID 37652990 DOI: 10.1038/s41598-023-41099-0  0.01
2023 Wu Y, Mumford P, Noy S, Cleverley K, Mrzyglod A, Luo D, van Dalen F, Verdoes M, Fisher EMC, Wiseman FK. Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B. Acta Neuropathologica Communications. 11: 132. PMID 37580797 DOI: 10.1186/s40478-023-01632-8  0.01
2023 Jiang X, Shen C, Caba B, Arnold DL, Elliott C, Zhu B, Fisher E, Belachew S, Gafson AR. Assessing the utility of magnetic resonance imaging-based "SuStaIn" disease subtyping for precision medicine in relapsing-remitting and secondary progressive multiple sclerosis. Multiple Sclerosis and Related Disorders. 77: 104869. PMID 37459715 DOI: 10.1016/j.msard.2023.104869  0.01
2023 Fisher E, Flynn MA, Pratap P, Vietas JA. Occupational Safety and Health Equity Impacts of Artificial Intelligence: A Scoping Review. International Journal of Environmental Research and Public Health. 20. PMID 37444068 DOI: 10.3390/ijerph20136221  0.01
2023 Jiang X, Shen C, Teunissen CE, Wessels M, Zetterberg H, Giovannoni G, Singh CM, Caba B, Elliott C, Fisher E, de Moor C, Belachew S, Gafson AR. Glial fibrillary acidic protein and multiple sclerosis progression independent of acute inflammation. Multiple Sclerosis (Houndmills, Basingstoke, England). 13524585231176732. PMID 37317870 DOI: 10.1177/13524585231176732  0.01
2023 Fisher EMC, Greensmith L, Malaspina A, Fratta P, Hanna MG, Schiavo G, Isaacs AM, Orrell RW, Cunningham TJ, Arozena AA. Opinion: more mouse models and more translation needed for ALS. Molecular Neurodegeneration. 18: 30. PMID 37143081 DOI: 10.1186/s13024-023-00619-2  0.01
2023 Cutter G, Rudick RA, de Moor C, Singh CM, Fisher E, Koster T, Lublin FD, Wolinsky JS, McFarland H, Jacobson S, Naylor ML. Serum neurofilament light-chain levels and long-term treatment outcomes in relapsing-remitting multiple sclerosis patients: A post hoc analysis of the randomized CombiRx trial. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 9: 20552173231169463. PMID 37139460 DOI: 10.1177/20552173231169463  0.01
2023 Redhead Y, Gibbins D, Lana-Elola E, Watson-Scales S, Dobson L, Krause M, Liu KJ, Fisher EMC, Green JBA, Tybulewicz VLJ. Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England). 150. PMID 37102702 DOI: 10.1242/dev.201077  0.01
2023 Elliott C, Rudko DA, Arnold DL, Fetco D, Elkady AM, Araujo D, Zhu B, Gafson A, Tian Z, Belachew S, Bradley DP, Fisher E. Lesion-level correspondence and longitudinal properties of paramagnetic rim and slowly expanding lesions in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 13524585231162262. PMID 37036134 DOI: 10.1177/13524585231162262  0.01
2023 Sloan K, Thomas J, Blackwell M, Voisard D, Lana-Elola E, Watson-Scales S, Roper DL, Wallace JM, Fisher EMC, Tybulewicz VLJ, Roper RJ. Genetic dissection of triplicated Hsa21 orthologs produces differential skeletal phenotypes in Down syndrome mouse models. Disease Models & Mechanisms. PMID 36939025 DOI: 10.1242/dmm.049927  0.01
2023 Muza PM, Bush D, Pérez-González M, Zouhair I, Cleverley K, Sopena ML, Aoidi R, West SJ, Good M, Tybulewicz VLJ, Walker MC, Fisher EMC, Chang P. Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. Iscience. 26: 106073. PMID 36818290 DOI: 10.1016/j.isci.2023.106073  0.01
2023 Epping GP, Fisher EL, Zeleznikow-Johnston AM, Pothos EM, Tsuchiya N. A Quantum Geometric Framework for Modeling Color Similarity Judgments. Cognitive Science. 47: e13231. PMID 36655940 DOI: 10.1111/cogs.13231  0.01
2022 Fisher ES, Chen Y, Sifuentes MM, Stubblefield JJ, Lozano D, Holstein DM, Ren J, Davenport M, DeRosa N, Chen TP, Nickel G, Liston TE, Lechleiter JD. Adenosine A1R/A3R agonist AST-004 reduces brain infarction in mouse and rat models of acute ischemic stroke. Frontiers in Stroke. 1. PMID 38348128 DOI: 10.3389/fstro.2022.1010928  0.01
2022 Caba B, Cafaro A, Lombard A, Arnold DL, Elliott C, Liu D, Jiang X, Gafson A, Fisher E, Belachew SM, Paragios N. Single-timepoint low-dimensional characterization and classification of acute versus chronic multiple sclerosis lesions using machine learning. Neuroimage. 265: 119787. PMID 36473647 DOI: 10.1016/j.neuroimage.2022.119787  0.01
2022 Sotirchos ES, Fitzgerald KC, Singh CM, Smith MD, Reyes-Mantilla M, Hersh CM, Hyland MH, Canissario R, Simmons SB, Arrambide G, Montalban X, Comabella M, Naismith RT, Qiao M, Krupp LB, ... ... Fisher E, et al. Associations of sNfL with clinico-radiological measures in a large MS population. Annals of Clinical and Translational Neurology. PMID 36427295 DOI: 10.1002/acn3.51704  0.01
2022 Fisher ES, Amarante MA, Lowry N, Lotz S, Farjood F, Temple S, Hill CE, Kiehl TR. Single cell profiling of CD45 spinal cord cells reveals microglial and B cell heterogeneity and crosstalk following spinal cord injury. Journal of Neuroinflammation. 19: 266. PMID 36333772 DOI: 10.1186/s12974-022-02627-3  0.01
2022 Ontaneda D, Mowry EM, Newsome SD, Naismith RT, Nicholas J, Fisher E, de Moor C, Bohn J, Ho PR, Sandrock A, Rudick R, Williams JR. Benefits of early treatment with natalizumab: a real-world study. Multiple Sclerosis and Related Disorders. 68: 104216. PMID 36288658 DOI: 10.1016/j.msard.2022.104216  0.01
2022 Mumford P, Tosh J, Anderle S, Wikberg EG, Lau G, Noy S, Cleverley K, Saito T, Saido TC, Yu E, Brinkmalm G, Portelius E, Blennow K, Zetterberg H, Tybulewicz V, ... Fisher EMC, et al. Genetic mapping of APP and amyloid-β biology modulation by trisomy 21. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35835549 DOI: 10.1523/JNEUROSCI.0521-22.2022  0.01
2022 Cannavo C, Cleverley K, Maduro C, Mumford P, Moulding D, Fisher EMC, Wiseman FK. Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome. Plos One. 17: e0262558. PMID 35544526 DOI: 10.1371/journal.pone.0262558  0.01
2022 Toner YC, Ghotbi AA, Naidu S, Sakurai K, van Leent MMT, Jordan S, Ordikhani F, Amadori L, Sofias AM, Fisher EL, Maier A, Sullivan N, Munitz J, Senders ML, Mason C, et al. Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation. Scientific Reports. 12: 6185. PMID 35418569 DOI: 10.1038/s41598-022-09590-2  0.01
2022 Nakamura K, Mokliatchouk O, Arnold DL, Yousry TA, Kappos L, Richert N, Ayling-Rouse K, Miller C, Fisher E. Effects of Dimethyl Fumarate on Brain Atrophy in Relapsing-Remitting Multiple Sclerosis: Pooled Analysis Phase 3 DEFINE and CONFIRM Studies. Frontiers in Neurology. 13: 809273. PMID 35370887 DOI: 10.3389/fneur.2022.809273  0.01
2022 Fisher E, James C, Mosca D, Currie BJ, Ralph AP. Evaluation of an ARF diagnosis calculator: a survey and content analysis. Bmc Medical Informatics and Decision Making. 22: 77. PMID 35346167 DOI: 10.1186/s12911-022-01816-7  0.01
2022 Devoy A, Price G, De Giorgio F, Bunton-Stasyshyn R, Thompson D, Gasco S, Allan A, Codner GF, Nair RR, Tibbit C, McLeod R, Ali Z, Noda J, Marrero-Gagliardi A, Brito-Armas JM, ... ... Fisher EMC, et al. Erratum: Generation and analysis of innovative genomically humanized knockin , (TDP-43), and mouse models. Iscience. 25: 103999. PMID 35296030 DOI: 10.1016/j.isci.2022.103999  0.01
2022 Welter C, Jarpe-Ratner E, Bonney T, Pinsker E, Fisher E, Deb N, Yankelev A, Kapadia D, Love M, Zanoni J. Evaluation Results From the Healthy Work Collaborative: A Cross-Sectoral Capacity Building Partnership to Address Precarious Employment. Health Promotion Practice. 15248399211069099. PMID 35220784 DOI: 10.1177/15248399211069099  0.01
2022 Brown AL, Wilkins OG, Keuss MJ, Hill SE, Zanovello M, Lee WC, Bampton A, Lee FCY, Masino L, Qi YA, Bryce-Smith S, Gatt A, Hallegger M, Fagegaltier D, Phatnani H, ... Fisher EMC, et al. TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. Nature. PMID 35197628 DOI: 10.1038/s41586-022-04436-3  0.01
2022 Ryerson LZ, Naismith RT, Krupp LB, Charvet LE, Liao S, Fisher E, de Moor C, Williams JR, Campbell N. No difference in radiologic outcomes for natalizumab patients treated with extended interval dosing compared with standard interval dosing: Real-world evidence from MS PATHS. Multiple Sclerosis and Related Disorders. 58: 103480. PMID 35051898 DOI: 10.1016/j.msard.2021.103480  0.01
2022 Zhao X, Fisher ES, Wang Y, Zuloaga K, Manley L, Temple S. 4D imaging analysis of the aging mouse neural stem cell niche reveals a dramatic loss of progenitor cell dynamism regulated by the RHO-ROCK pathway. Stem Cell Reports. PMID 35030320 DOI: 10.1016/j.stemcr.2021.12.007  0.01
2021 Devoy A, Price G, De Giorgio F, Bunton-Stasyshyn R, Thompson D, Gasco S, Allan A, Codner GF, Nair RR, Tibbit C, McLeod R, Ali Z, Noda J, Marrero-Gagliardi A, Brito-Armas JM, ... ... Fisher EMC, et al. Generation and analysis of innovative genomically humanized knockin , (TDP-43), and mouse models. Iscience. 24: 103463. PMID 34988393 DOI: 10.1016/j.isci.2021.103463  0.01
2021 Yu Y, Payne C, Marina N, Korsak A, Southern P, García-Prieto A, Christie IN, Baker RR, Fisher EMC, Wells JA, Kalber TL, Pankhurst QA, Gourine AV, Lythgoe MF. Remote and Selective Control of Astrocytes by Magnetomechanical Stimulation. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104194. PMID 34927381 DOI: 10.1002/advs.202104194  0.01
2021 Tosh J, Tybulewicz V, Fisher EMC. Mouse models of aneuploidy to understand chromosome disorders. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 34719726 DOI: 10.1007/s00335-021-09930-z  0.01
2021 Calabresi PA, Kappos L, Giovannoni G, Plavina T, Koulinska I, Edwards MR, Kieseier B, de Moor C, Sotirchos ES, Fisher E, Rudick RA, Sandrock A. Measuring treatment response to advance precision medicine for multiple sclerosis. Annals of Clinical and Translational Neurology. PMID 34704393 DOI: 10.1002/acn3.51471  0.01
2021 Elliott C, Momayyezsiahkal P, Arnold DL, Liu D, Ke J, Zhu L, Zhu B, George IC, Bradley DP, Fisher E, Cahir-McFarland E, Stys PK, Geurts JJG, Franchimont N, Gafson A, et al. Abnormalities in normal-appearing white matter from which multiple sclerosis lesions arise. Brain Communications. 3: fcab176. PMID 34557664 DOI: 10.1093/braincomms/fcab176  0.01
2021 Heisser RH, Aubin CA, Peretz O, Kincaid N, An HS, Fisher EM, Sobhani S, Pepiot P, Gat AD, Shepherd RF. Valveless microliter combustion for densely packed arrays of powerful soft actuators. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34556574 DOI: 10.1073/pnas.2106553118  0.01
2021 Lana-Elola E, Cater H, Watson-Scales S, Greenaway S, Müller-Winkler J, Gibbins D, Nemes M, Slender A, Hough T, Keskivali-Bond P, Scudamore CL, Herbert E, Banks GT, Mobbs H, Canonica T, ... ... Fisher EMC, et al. Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of down syndrome-related phenotypes. Disease Models & Mechanisms. PMID 34477842 DOI: 10.1242/dmm.049157  0.01
2021 Garone MG, Birsa N, Rosito M, Salaris F, Mochi M, de Turris V, Nair RR, Cunningham TJ, Fisher EMC, Morlando M, Fratta P, Rosa A. ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity. Communications Biology. 4: 1025. PMID 34471224 DOI: 10.1038/s42003-021-02538-8  0.01
2021 Dierssen M, Herault Y, Helguera P, Martínez de Lagran M, Vazquez A, Christian B, Carmona-Iragui M, Wiseman F, Mobley W, Fisher EMC, Brault V, Esbensen A, Jacola LM, Potier MC, Hamlett ED, et al. Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society. Molecular Syndromology. 12: 202-218. PMID 34421499 DOI: 10.1159/000514437  0.01
2021 Toussaint N, Redhead Y, Vidal-García M, Lo Vercio L, Liu W, Fisher EMC, Hallgrímsson B, Tybulewicz VLJ, Schnabel JA, Green JBA. A landmark-free morphometrics pipeline for high-resolution phenotyping: application to a mouse model of Down syndrome. Development (Cambridge, England). 148. PMID 34308975 DOI: 10.1242/dev.188631  0.01
2021 Wu Y, Whittaker HT, Noy S, Cleverley K, Brault V, Herault Y, Fisher EMC, Wiseman FK. The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model. Plos One. 16: e0242236. PMID 34292972 DOI: 10.1371/journal.pone.0242236  0.01
2021 Birsa N, Ule AM, Garone MG, Tsang B, Mattedi F, Chong PA, Humphrey J, Jarvis S, Pisiren M, Wilkins OG, Nosella ML, Devoy A, Bodo C, de la Fuente RF, Fisher EMC, et al. FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation. Science Advances. 7. PMID 34290090 DOI: 10.1126/sciadv.abf8660  0.01
2021 Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K, Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models. Scientific Reports. 11: 14966. PMID 34272456 DOI: 10.1038/s41598-021-94313-2  0.01
2021 Wyatt S, Mohammed MA, Fisher E, McConkey R, Spilsbury P. Impact of the SARS-CoV-2 pandemic and associated lockdown measures on attendances at emergency departments in English hospitals: A retrospective database study. The Lancet Regional Health. Europe. 2: 100034. PMID 34173630 DOI: 10.1016/j.lanepe.2021.100034  0.01
2021 Mejia Maza A, Jarvis S, Lee WC, Cunningham TJ, Schiavo G, Secrier M, Fratta P, Sleigh JN, Fisher EMC, Sudre CH. NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease. Scientific Reports. 11: 12251. PMID 34112844 DOI: 10.1038/s41598-021-91094-6  0.01
2021 Kalisch-Smith JI, Ved N, Szumska D, Munro J, Troup M, Harris SE, Rodriguez-Caro H, Jacquemot A, Miller JJ, Stuart EM, Wolna M, Hardman E, Prin F, Lana-Elola E, Aoidi R, ... Fisher EMC, et al. Maternal iron deficiency perturbs embryonic cardiovascular development in mice. Nature Communications. 12: 3447. PMID 34103494 DOI: 10.1038/s41467-021-23660-5  0.01
2021 Brier MR, Snyder AZ, Tanenbaum A, Rudick RA, Fisher E, Jones S, Shimony JS, Cross AH, Benzinger TLS, Naismith RT. Quantitative signal properties from standardized MRIs correlate with multiple sclerosis disability. Annals of Clinical and Translational Neurology. PMID 33943045 DOI: 10.1002/acn3.51354  0.01
2021 Cleverley K, Lee WC, Mumford P, Collins T, Rickman M, Cunningham TJ, Cleak J, Mianne J, Szoke-Kovacs Z, Stewart M, Teboul L, Maduro C, Wells S, Wiseman FK, Fisher EMC. A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 33713180 DOI: 10.1007/s00335-021-09864-6  0.01
2021 Toussaint N, Redhead Y, Vidal-García M, Lo Vercio L, Liu W, Fisher EMC, Hallgrímsson B, Tybulewicz VLJ, Schnabel JA, Green JBA. A landmark-free morphometrics pipeline for high-resolution phenotyping: application to a mouse model of Down syndrome. Development (Cambridge, England). 148. PMID 33712441 DOI: 10.1242/dev.188631  0.01
2021 Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K, Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models. Scientific Reports. 11: 5736. PMID 33707583 DOI: 10.1038/s41598-021-85062-3  0.01
2020 Plavina T, Singh CM, Sangurdekar D, de Moor C, Engle B, Gafson A, Goyal J, Fisher E, Szak S, Kinkel RP, Sandrock AW, Su R, Kieseier BC, Rudick RA. Association of Serum Neurofilament Light Levels With Long-term Brain Atrophy in Patients With a First Multiple Sclerosis Episode. Jama Network Open. 3: e2016278. PMID 33151313 DOI: 10.1001/jamanetworkopen.2020.16278  0.01
2020 Priem B, van Leent MMT, Teunissen AJP, Sofias AM, Mourits VP, Willemsen L, Klein ED, Oosterwijk RS, Meerwaldt AE, Munitz J, Prévot G, Vera Verschuur A, Nauta SA, van Leeuwen EM, Fisher EL, et al. Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition. Cell. 183: 786-801.e19. PMID 33125893 DOI: 10.1016/j.cell.2020.09.059  0.01
2020 Dong P, Fisher EA, Meli MV, Trudel S. Tuning the magnetism of gold nanoparticles by changing the thiol coating. Nanoscale. PMID 32966519 DOI: 10.1039/d0nr05674j  0.01
2020 Rayon T, Stamataki D, Perez-Carrasco R, Garcia-Perez L, Barrington C, Melchionda M, Exelby K, Lazaro J, Tybulewicz VLJ, Fisher EMC, Briscoe J. Species-specific pace of development is associated with differences in protein stability. Science (New York, N.Y.). 369. PMID 32943498 DOI: 10.1126/Science.Aba7667  0.01
2020 Welter C, Jarpe-Ratner E, Bonney T, C Pinsker E, Fisher E, Yankelev A, Kapadia D, Love M, Zanoni J. Development of the Healthy Work Collaborative: Findings From an Action Research Study to Inform a Policy, Systems, and Environmental Change Capacity-Building Initiative Addressing Precarious Employment. Health Promotion Practice. 1524839920953116. PMID 32875915 DOI: 10.1177/1524839920953116  0.01
2020 Mowry EM, Bermel RA, Williams JR, Benzinger TLS, de Moor C, Fisher E, Hersh CM, Hyland MH, Izbudak I, Jones SE, Kieseier BC, Kitzler HH, Krupp L, Lui YW, Montalban X, et al. Harnessing Real-World Data to Inform Decision-Making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS). Frontiers in Neurology. 11: 632. PMID 32849170 DOI: 10.3389/Fneur.2020.00632  0.01
2020 Ma D, Cardoso MJ, Zuluaga MA, Modat M, Powell NM, Wiseman FK, Cleary JO, Sinclair B, Harrison IF, Siow B, Popuri K, Lee S, Matsubara JA, Sarunic MV, Beg MF, ... ... Fisher EMC, et al. Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellum of the Tc1 mouse model of Down Syndrome - a comprehensive morphometric analysis with active staining contrast-enhanced MRI. Neuroimage. 117271. PMID 32835824 DOI: 10.1016/J.Neuroimage.2020.117271  0.01
2020 Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus J, Shi J, Heckman M, Spiegel M, Cook C, Song Y, Yue M, Daughrity L, Carlomagno Y, Jansen-West K, ... Fisher EM, et al. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. The Journal of Clinical Investigation. PMID 32790644 DOI: 10.1172/Jci139741  0.01
2020 Beynon C, Pashayan N, Fisher E, Hargreaves DS, Bailey L, Raine R. A cross-sectional study using the Childhood Measurement Programme for Wales to examine population-level risk factors associated with childhood obesity. Public Health Nutrition. 1-9. PMID 32744211 DOI: 10.1017/S1368980020001913  0.01
2020 Nair RR, Tibbit C, Thompson D, McLeod R, Nakhuda A, Simon MM, Baloh RH, Fisher EMC, Isaacs AM, Cunningham TJ. Sizing, stabilising, and cloning repeat-expansions for gene targeting constructs. Methods (San Diego, Calif.). PMID 32721467 DOI: 10.1016/J.Ymeth.2020.07.007  0.01
2020 Lana-Elola E, Watson-Scales S, Slender A, Gibbins D, Martineau A, Douglas C, Mohun T, Fisher EM, Tybulewicz VL. Correction: Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 9. PMID 32692312 DOI: 10.7554/eLife.61021  0.01
2020 Humphrey J, Birsa N, Milioto C, McLaughlin M, Ule AM, Robaldo D, Eberle AB, Kräuchi R, Bentham M, Brown AL, Jarvis S, Bodo C, Garone MG, Devoy A, Soraru G, ... Fisher EMC, et al. FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention. Nucleic Acids Research. PMID 32479602 DOI: 10.1093/Nar/Gkaa410  0.01
2020 Sofias AM, Toner YC, Meerwaldt AE, van Leent MMT, Soultanidis G, Elschot M, Gonai H, Grendstad K, Flobak Å, Neckmann U, Wolowczyk C, Fisher EL, Reiner T, Davies CL, Bjørkøy G, et al. Tumor Targeting by αvβ3-Integrin Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking. Acs Nano. PMID 32413260 DOI: 10.1021/Acsnano.9B08693  0.01
2020 Cunningham TJ, Fisher E, Fratta P, Gilthorpe JD. DNA Editing for Amyotrophic Lateral Sclerosis: Leading Off First Base. The Crispr Journal. 3: 75-77. PMID 32315228 DOI: 10.1089/crispr.2020.29087.tcu  0.01
2020 Thomas JR, LaCombe J, Long R, Lana-Elola E, Watson-Scales S, Wallace JM, Fisher EMC, Tybulewicz VLJ, Roper RJ. Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome. Bone. 115367. PMID 32305495 DOI: 10.1016/J.Bone.2020.115367  0.01
2020 Nakamura K, Rudick RA, Ontaneda D, Fox RJ, Trapp BD, Fisher E. Fourteen-year serial MRIs of patients with mild and severe courses of MS. Neurology. Clinical Practice. 10: e5-e6. PMID 32190426 DOI: 10.1212/CPJ.0000000000000695  0.01
2020 Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G. Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes. Cell Reports. 30: 3655-3662.e2. PMID 32187538 DOI: 10.1016/J.Celrep.2020.02.078  0.01
2020 Terenzio M, Di Pizio A, Rishal I, Marvaldi L, Di Matteo P, Kawaguchi R, Coppola G, Schiavo G, Fisher EMC, Fainzilber M. DYNLRB1 is essential for dynein mediated transport and neuronal survival. Neurobiology of Disease. 104816. PMID 32088381 DOI: 10.1016/J.Nbd.2020.104816  0.01
2020 Cannavo C, Tosh J, Fisher EMC, Wiseman FK. Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21. Progress in Brain Research. 251: 181-208. PMID 32057307 DOI: 10.1016/Bs.Pbr.2019.10.004  0.01
2020 Fisher EA, Paterson GK. Prevalence and characterisation of methicillin-resistant staphylococci from bovine bulk tank milk in England and Wales. Journal of Global Antimicrobial Resistance. PMID 32006753 DOI: 10.1016/j.jgar.2020.01.013  0.01
2020 Chang P, Bush D, Schorge S, Good M, Canonica T, Shing N, Noy S, Wiseman FK, Burgess N, Tybulewicz VLJ, Walker MC, Fisher EMC. Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome. Cell Reports. 30: 1152-1163.e4. PMID 31995755 DOI: 10.1016/J.Celrep.2019.12.065  0.01
2019 Baldassari LE, Planchon SM, Bermel RA, Nakamura K, Fisher E, Feng J, Sakaie KE, Ontaneda D, Cohen JA. Serum neurofilament light chain concentration in a phase 1/2 trial of autologous mesenchymal stem cell transplantation. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 5: 2055217319887198. PMID 31723439 DOI: 10.1177/2055217319887198  0.01
2019 Kuhle J, Plavina T, Barro C, Disanto G, Sangurdekar D, Singh CM, de Moor C, Engle B, Kieseier BC, Fisher E, Kappos L, Rudick RA, Goyal J. Neurofilament light levels are associated with long-term outcomes in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519885613. PMID 31680621 DOI: 10.1177/1352458519885613  0.01
2019 Liu ZS, Huang C, Ma L, Dy E, Xie Z, Tufa K, Fisher EA, Zhou J, Morin K, Aziz M, Meints C, O'Kane M, Tallon L. The characteristic properties of waste rock piles in terms of metal leaching. Journal of Contaminant Hydrology. 226: 103540. PMID 31434016 DOI: 10.1016/j.jconhyd.2019.103540  0.01
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Fisher E, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.01
2019 Cadavid D, Mellion M, Hupperts R, Edwards KR, Calabresi PA, Drulović J, Giovannoni G, Hartung HP, Arnold DL, Fisher E, Rudick R, Mi S, Chai Y, Li J, Zhang Y, et al. Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial. The Lancet. Neurology. PMID 31285147 DOI: 10.1016/S1474-4422(19)30137-1  0.01
2019 Feng J, Offerman E, Lin J, Fisher E, Planchon SM, Sakaie K, Lowe M, Nakamura K, Cohen JA, Ontaneda D. Exploratory MRI measures after intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 5: 2055217319856035. PMID 31236284 DOI: 10.1177/2055217319856035  0.01
2019 Nair RR, Corrochano S, Gasco S, Tibbit C, Thompson D, Maduro C, Ali Z, Fratta P, Arozena AA, Cunningham TJ, Fisher EMC. Uses for humanised mouse models in precision medicine for neurodegenerative disease. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 31203387 DOI: 10.1007/S00335-019-09807-2  0.01
2019 Ahlfors H, Anyanwu N, Pakanavicius E, Dinischiotu N, Lana-Elola E, Watson-Scales S, Tosh J, Wiseman F, Briscoe J, Page K, Fisher EMC, Tybulewicz VLJ. Gene expression dysregulation domains are not a specific feature of Down syndrome. Nature Communications. 10: 2489. PMID 31171815 DOI: 10.1038/S41467-019-10129-9  0.01
2019 Fisher EMC, Bannerman DM. Mouse models of neurodegeneration: Know your question, know your mouse. Science Translational Medicine. 11. PMID 31118292 DOI: 10.1126/Scitranslmed.Aaq1818  0.01
2019 Granno S, Nixon-Abell J, Berwick DC, Tosh J, Heaton G, Almudimeegh S, Nagda Z, Rain JC, Zanda M, Plagnol V, Tybulewicz VLJ, Cleverley K, Wiseman FK, Fisher EMC, Harvey K. Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific Reports. 9: 7322. PMID 31086297 DOI: 10.1038/S41598-019-43820-4  0.01
2019 Zhu F, Nair RR, Fisher EMC, Cunningham TJ. Humanising the mouse genome piece by piece. Nature Communications. 10: 1845. PMID 31015419 DOI: 10.1038/S41467-019-09716-7  0.01
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Fisher E, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.01
2019 De Giorgio F, Maduro C, Fisher EMC, Acevedo-Arozena A. Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis. Disease Models & Mechanisms. 12. PMID 30626575 DOI: 10.1242/Dmm.037424  0.01
2018 Hithersay R, Startin CM, Hamburg S, Mok KY, Hardy J, Fisher EMC, Tybulewicz VLJ, Nizetic D, Strydom A. Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years. Jama Neurology. PMID 30452522 DOI: 10.1001/Jamaneurol.2018.3616  0.01
2018 Wagner W, Fisher E, Pascual P. Whose science? A new era in regulatory "science wars". Science (New York, N.Y.). 362: 636-639. PMID 30409870 DOI: 10.1126/science.aau3205  0.01
2018 Sivakumar P, De Giorgio F, Ule AM, Neeves J, Nair RR, Bentham M, Birsa N, Humphrey J, Plagnol V, Acevedo-Arozena A, Cunningham TJ, Fisher EMC, Fratta P. TDP-43 mutations increase HNRNP A1-7B through gain of splicing function. Brain : a Journal of Neurology. PMID 30364928 DOI: 10.1093/brain/awy260  0.01
2018 Trapp BD, Vignos M, Dudman J, Chang A, Fisher E, Staugaitis SM, Battapady H, Mork S, Ontaneda D, Jones SE, Fox RJ, Chen J, Nakamura K, Rudick RA. Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study. The Lancet. Neurology. PMID 30143361 DOI: 10.1016/S1474-4422(18)30245-X  0.01
2018 Li S, Lucey PG, Milliken RE, Hayne PO, Fisher E, Williams JP, Hurley DM, Elphic RC. Direct evidence of surface exposed water ice in the lunar polar regions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30126996 DOI: 10.1073/Pnas.1802345115  0.01
2018 Knight S, Takagi M, Fisher E, Anderson V, Lannin NA, Tavender E, Scheinberg A. A systematic critical appraisal of evidence-based clinical practice guidelines for the rehabilitation of children with moderate or severe acquired brain injury. Archives of Physical Medicine and Rehabilitation. PMID 29966649 DOI: 10.1016/j.apmr.2018.05.031  0.01
2018 Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, ... ... Fisher EMC, et al. Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP. Brain : a Journal of Neurology. PMID 29945247 DOI: 10.1093/Brain/Awy159  0.01
2018 MacFadyen AC, Fisher EA, Costa B, Cullen C, Paterson GK. Genome analysis of methicillin resistance in Macrococcus caseolyticus from dairy cattle in England and Wales. Microbial Genomics. PMID 29916803 DOI: 10.1099/mgen.0.000191  0.01
2018 Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo C, Collins T, Conicella AE, Mejia Maza A, ... ... Fisher EM, et al. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. The Embo Journal. PMID 29764981 DOI: 10.15252/Embj.201798684  0.01
2018 Watson-Scales S, Kalmar B, Lana-Elola E, Gibbins D, La Russa F, Wiseman F, Williamson M, Saccon R, Slender A, Olerinyova A, Mahmood R, Nye E, Cater H, Wells S, Yu YE, ... ... Fisher EMC, et al. Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. Plos Genetics. 14: e1007383. PMID 29746474 DOI: 10.1371/Journal.Pgen.1007383  0.01
2018 Martens I, Fisher EA, Bizzotto D. Direct mapping of heterogeneous surface coverage in DNA-functionalized gold surfaces with correlated electron and fluorescence microscopy. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29361826 DOI: 10.1021/Acs.Langmuir.7B03766  0.01
2018 Miles P, Fisher E, Pandis N. Assessment of the rate of premolar extraction space closure in the maxillary arch with the AcceleDent Aura appliance vs no appliance in adolescents: A single-blind randomized clinical trial. American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics. 153: 8-14. PMID 29287658 DOI: 10.1016/j.ajodo.2017.08.007  0.01
2017 Fisher EA, Lucey PG, Lemelin M, Greenhagen BT, Siegler MA, Mazarico E, Aharonson O, Williams JP, Hayne PO, Neumann GA, Paige DA, Smith DE, Zuber MT. Evidence for surface water ice in the lunar polar regions using reflectance measurements from the Lunar Orbiter Laser Altimeter and temperature measurements from the Diviner Lunar Radiometer Experiment. Icarus. 74-85. PMID 32367891 DOI: 10.1016/J.Icarus.2017.03.023  0.01
2017 Fisher E, Kraus J, Kuluski K, Allatt P. Church Services in a Complex Continuing Care Hospital: Why Bother? The Journal of Pastoral Care & Counseling : Jpcc. 71: 274-283. PMID 29224527 DOI: 10.1177/1542305017744492  0.01
2017 Naert G, Ferré V, Keller E, Slender A, Gibbins D, Fisher EM, Tybulewicz VL, Maurice T. In vivo and ex vivo analyses of amyloid toxicity in the Tc1 mouse model of Down syndrome. Journal of Psychopharmacology (Oxford, England). 269881117743484. PMID 29215943 DOI: 10.1177/0269881117743484  0.01
2017 Zheng Y, Lee JC, Rudick R, Fisher E. Long-Term Magnetization Transfer Ratio Evolution in Multiple Sclerosis White Matter Lesions. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 29076591 DOI: 10.1111/jon.12480  0.01
2017 Tosh JL, Rickman M, Rhymes E, Norona FE, Clayton E, Mucke L, Isaacs AM, Fisher EMC, Wiseman FK. The integration site of the APP transgene in the J20 mouse model of Alzheimer's disease. Wellcome Open Research. 2: 84. PMID 29062914 DOI: 10.12688/wellcomeopenres.12237.2  0.01
2017 Fisher EA, Leung KK, Casanova-Moreno J, Masuda T, Young JF, Bizzotto D. Quantifying the selective modification of Au(111) facets via electrochemical and electroless treatments for manipulating gold nanorod surface composition. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29058912 DOI: 10.1021/Acs.Langmuir.7B03021  0.01
2017 Devoy A, Kalmar B, Stewart M, Park H, Burke B, Noy SJ, Redhead Y, Humphrey J, Lo K, Jaeger J, Mejia Maza A, Sivakumar P, Bertolin C, Soraru G, Plagnol V, ... Fisher EMC, et al. Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice. Brain : a Journal of Neurology. PMID 29053787 DOI: 10.1093/Brain/Awx248  0.01
2017 Herault Y, Delabar JM, Fisher EMC, Tybulewicz VLJ, Yu E, Brault V. Rodent models in Down syndrome research: impact and future opportunities. Disease Models & Mechanisms. 10: 1165-1186. PMID 28993310 DOI: 10.1242/Dmm.029728  0.01
2017 Dekker AD, Vermeiren Y, Albac C, Lana-Elola E, Watson-Scales S, Gibbins D, Aerts T, Van Dam D, Fisher EMC, Tybulewicz VLJ, Potier MC, De Deyn PP. Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models. Neurobiology of Disease. PMID 28624415 DOI: 10.1016/J.Nbd.2017.06.007  0.01
2017 Banerjee S, Mino E, Fisher ES, Bhat MA. A Versatile Genetic Tool to Study Midline Glia Function in the Drosophila CNS. Developmental Biology. PMID 28602954 DOI: 10.1016/J.Ydbio.2017.06.010  0.01
2017 Holmes HE, Powell NM, Ma D, Ismail O, Harrison IF, Wells JA, Colgan N, O'Callaghan JM, Johnson RA, Murray TK, Ahmed Z, Heggenes M, Fisher A, Cardoso MJ, Modat M, ... Fisher EM, et al. Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy. Frontiers in Neuroinformatics. 11: 20. PMID 28408879 DOI: 10.3389/Fninf.2017.00020  0.01
2017 Cohen JA, Imrey PB, Planchon SM, Bermel RA, Fisher E, Fox RJ, Bar-Or A, Sharp SL, Skaramagas TT, Jagodnik P, Karafa M, Morrison S, Reese Koc J, Gerson SL, Lazarus HM. Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517703802. PMID 28381130 DOI: 10.1177/1352458517703802  0.01
2016 Miles P, Fisher E. Assessment of the changes in arch perimeter and irregularity in the mandibular arch during initial alignment with the AcceleDent Aura appliance vs no appliance in adolescents: A single-blind randomized clinical trial. American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics. 150: 928-936. PMID 27894541 DOI: 10.1016/j.ajodo.2016.07.016  0.01
2016 Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, ... Fisher EM, et al. Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons. Elife. 5. PMID 27692071 DOI: 10.7554/Elife.20337  0.01
2016 Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S. Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome. Plos One. 11: e0162974. PMID 27658297 DOI: 10.1371/Journal.Pone.0162974  0.01
2016 Bradford SM, Fisher EA, Meli MV. Ligand Shell Composition-Dependent Effects on the Apparent Hydrophobicity and Film Behavior of Gold Nanoparticles at the Air - Water Interface. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27594307 DOI: 10.1021/acs.langmuir.6b02238  0.01
2016 Arnold DL, Fisher E, Brinar VV, Cohen JA, Coles AJ, Giovannoni G, Hartung HP, Havrdova E, Selmaj KW, Stojanovic M, Weiner HL, Lake SL, Margolin DH, Thomas DR, Panzara MA, et al. Superior MRI outcomes with alemtuzumab compared with subcutaneous interferon β-1a in MS. Neurology. PMID 27590291 DOI: 10.1212/Wnl.0000000000003169  0.01
2016 Buss L, Fisher E, Hardy J, Nizetic D, Groet J, Pulford L, Strydom A. Intracerebral haemorrhage in Down syndrome: protected or predisposed? F1000research. 5. PMID 27239286 DOI: 10.12688/F1000Research.7819.1  0.01
2016 Peiris H, Duffield MD, Fadista J, Jessup CF, Kashmir V, Genders AJ, McGee SL, Martin AM, Saiedi M, Morton N, Carter R, Cousin MA, Kokotos AC, Oskolkov N, Volkov P, ... Fisher EM, et al. A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes. Plos Genetics. 12: e1006033. PMID 27195491 DOI: 10.1371/Journal.Pgen.1006033  0.01
2016 Karmiloff-Smith A, Al-Janabi T, D'Souza H, Groet J, Massand E, Mok K, Startin C, Fisher E, Hardy J, Nizetic D, Tybulewicz V, Strydom A. The importance of understanding individual differences in Down syndrome. F1000research. 5. PMID 27019699 DOI: 10.12688/F1000Research.7506.1  0.01
2016 Holmes MA, Harrison EM, Fisher EA, Graham EM, Parkhill J, Foster G, Paterson GK. Genomic Analysis of Companion Rabbit Staphylococcus aureus. Plos One. 11: e0151458. PMID 26963381 DOI: 10.1371/journal.pone.0151458  0.01
2016 Holmes HE, Colgan N, Ismail O, Ma D, Powell NM, O'Callaghan JM, Harrison IF, Johnson RA, Murray TK, Ahmed Z, Heggenes M, Fisher A, Cardoso MJ, Modat M, Walker-Samuel S, Fisher EM, et al. Imaging the accumulation and suppression of tau pathology using multiparametric MRI. Neurobiology of Aging. 39: 184-94. PMID 26923415 DOI: 10.1016/J.Neurobiolaging.2015.12.001  0.01
2016 Parpura V, Fisher ES, Lechleiter JD, Schousboe A, Waagepetersen HS, Brunet S, Baltan S, Verkhratsky A. Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology. Neurochemical Research. PMID 26915104 DOI: 10.1007/S11064-016-1848-6  0.01
2016 Hall JH, Wiseman FK, Fisher EM, Tybulewicz VL, Harwood JL, Good MA. Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory. Neurobiology of Learning and Memory. PMID 26868479 DOI: 10.1016/J.Nlm.2016.02.002  0.01
2016 Steventon A, Ariti C, Fisher E, Bardsley M. Effect of telehealth on hospital utilisation and mortality in routine clinical practice: a matched control cohort study in an early adopter site. Bmj Open. 6: e009221. PMID 26842270 DOI: 10.1136/bmjopen-2015-009221  0.01
2016 Lana-Elola E, Watson-Scales S, Slender A, Gibbins D, Martineau A, Douglas C, Mohun T, Fisher EM, Tybulewicz VLj. Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 5. PMID 26765563 DOI: 10.7554/eLife.11614  0.01
2015 Stone LA, Cutter GR, Fisher E, Richert N, McCartin J, Ohayon J, Bash C, McFarland H. Relapse May Serve as a Mediator Variable in Longitudinal Outcomes in Multiple Sclerosis. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 26686343 DOI: 10.1111/Jon.12321  0.01
2015 Joyce PI, Fratta P, Landman AS, McGoldrick P, Wackerhage H, Groves M, Busam BS, Galino J, Corrochano S, Beskina OA, Esapa C, Ryder E, Carter S, Stewart M, Codner G, ... ... Fisher EM, et al. Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration. Human Molecular Genetics. PMID 26604141 DOI: 10.1093/Hmg/Ddv471  0.01
2015 Choong XY, Tosh JL, Pulford LJ, Fisher EM. Dissecting Alzheimer disease in Down syndrome using mouse models. Frontiers in Behavioral Neuroscience. 9: 268. PMID 26528151 DOI: 10.3389/Fnbeh.2015.00268  0.01
2015 Abdelkarim S, Morgan S, Plagnol V, Lu CH, Adamson G, Howard R, Malaspina A, Orrell R, Sharma N, Sidle K, Clarke J, Fox NC, Rossor MN, Warren JD, Clark CN, ... ... Fisher EM, et al. CHCHD10 Pro34Ser is not a highly penetrant pathogenic variant for amyotrophic lateral sclerosis and frontotemporal dementia. Brain : a Journal of Neurology. PMID 26362910 DOI: 10.1093/Brain/Awv223  0.01
2015 Wiseman FK, Al-Janabi T, Hardy J, Karmiloff-Smith A, Nizetic D, Tybulewicz VL, Fisher EM, Strydom A. A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome. Nature Reviews. Neuroscience. 16: 564-74. PMID 26243569 DOI: 10.1038/Nrn3983  0.01
2015 Fisher EM, Peters J. Mary Frances Lyon (1925–2014). Cell. 160: 577-8. PMID 25823359 DOI: 10.1016/J.Cell.2015.01.039  0.01
2015 Wells JA, Holmes HE, O'Callaghan JM, Colgan N, Ismail O, Fisher EM, Siow B, Murray TK, Schwarz AJ, O'Neill MJ, Collins EC, Lythgoe MF. Increased cerebral vascular reactivity in the tau expressing rTg4510 mouse: evidence against the role of tau pathology to impair vascular health in Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 359-62. PMID 25515210 DOI: 10.1038/jcbfm.2014.224  0.01
2015 Bunton-Stasyshyn RK, Saccon RA, Fratta P, Fisher EM. SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology: New and Renascent Themes. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 21: 519-29. PMID 25492944 DOI: 10.1177/1073858414561795  0.01
2015 Joyce PI, Mcgoldrick P, Saccon RA, Weber W, Fratta P, West SJ, Zhu N, Carter S, Phatak V, Stewart M, Simon M, Kumar S, Heise I, Bros-Facer V, Dick J, ... Fisher EM, et al. A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity. Human Molecular Genetics. 24: 1883-97. PMID 25468678 DOI: 10.1093/Hmg/Ddu605  0.01
2015 Fratta P, Polke JM, Newcombe J, Mizielinska S, Lashley T, Poulter M, Beck J, Preza E, Devoy A, Sidle K, Howard R, Malaspina A, Orrell RW, Clarke J, Lu CH, ... Fisher EM, et al. Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion. Neurobiology of Aging. 36: 546.e1-7. PMID 25179228 DOI: 10.1016/J.Neurobiolaging.2014.07.037  0.01
2014 Mizielinska S, Grönke S, Niccoli T, Ridler CE, Clayton EL, Devoy A, Moens T, Norona FE, Woollacott IO, Pietrzyk J, Cleverley K, Nicoll AJ, Pickering-Brown S, Dols J, Cabecinha M, ... ... Fisher EM, et al. C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins. Science (New York, N.Y.). 345: 1192-4. PMID 25103406 DOI: 10.1126/Science.1256800  0.01
2014 Fratta P, Nirmalananthan N, Masset L, Skorupinska I, Collins T, Cortese A, Pemble S, Malaspina A, Fisher EM, Greensmith L, Hanna MG. Correlation of clinical and molecular features in spinal bulbar muscular atrophy. Neurology. 82: 2077-84. PMID 24814851 DOI: 10.1212/Wnl.0000000000000507  0.01
2014 Woolf D, Lehmann J, Fisher EM, Angenent LT. Biofuels from pyrolysis in perspective: trade-offs between energy yields and soil-carbon additions. Environmental Science & Technology. 48: 6492-9. PMID 24787482 DOI: 10.1021/Es500474Q  0.01
2014 Garrett CA, Barri M, Kuta A, Soura V, Deng W, Fisher EM, Schiavo G, Hafezparast M. DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy. Brain : a Journal of Neurology. 137: 1883-93. PMID 24755273 DOI: 10.1093/Brain/Awu097  0.01
2014 Ma D, Cardoso MJ, Modat M, Powell N, Wells J, Holmes H, Wiseman F, Tybulewicz V, Fisher E, Lythgoe MF, Ourselin S. Automatic structural parcellation of mouse brain MRI using multi-atlas label fusion. Plos One. 9: e86576. PMID 24475148 DOI: 10.1371/Journal.Pone.0086576  0.01
2014 Ricketts T, McGoldrick P, Fratta P, de Oliveira HM, Kent R, Phatak V, Brandner S, Blanco G, Greensmith L, Acevedo-Arozena A, Fisher EM. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. Plos One. 9: e85962. PMID 24465814 DOI: 10.1371/Journal.Pone.0085962  0.01
2014 Cortese A, Plagnol V, Brady S, Simone R, Lashley T, Acevedo-Arozena A, de Silva R, Greensmith L, Holton J, Hanna MG, Fisher EM, Fratta P. Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy. Neurobiology of Aging. 35: 1491-8. PMID 24462217 DOI: 10.1016/J.Neurobiolaging.2013.12.029  0.01
2014 Fratta P, Charnock J, Collins T, Devoy A, Howard R, Malaspina A, Orrell R, Sidle K, Clarke J, Shoai M, Lu CH, Hardy J, Plagnol V, Fisher EM. Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 506-8. PMID 24309268 DOI: 10.1136/Jnnp-2013-306761  0.01
2014 Fratta P, Collins T, Pemble S, Nethisinghe S, Devoy A, Giunti P, Sweeney MG, Hanna MG, Fisher EM. Sequencing analysis of the spinal bulbar muscular atrophy CAG expansion reveals absence of repeat interruptions. Neurobiology of Aging. 35: 443.e1-3. PMID 24041967 DOI: 10.1016/J.Neurobiolaging.2013.07.015  0.01
2013 Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, ... ... Fisher EM, et al. Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4: 2816. PMID 24281383 DOI: 10.1038/Ncomms3816  0.01
2013 Haas MA, Bell D, Slender A, Lana-Elola E, Watson-Scales S, Fisher EMC, Tybulewicz VLJ, Guillemot F. Alterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down syndrome Plos One. 8. PMID 24205261 DOI: 10.1371/Journal.Pone.0078561  0.01
2013 Schiavo G, Greensmith L, Hafezparast M, Fisher EM. Cytoplasmic dynein heavy chain: the servant of many masters. Trends in Neurosciences. 36: 641-51. PMID 24035135 DOI: 10.1016/J.Tins.2013.08.001  0.01
2013 Fratta P, Hanna MG, Fisher EM, Sidle K. An unusual presentation for SOD1-ALS: isolated facial diplegia. Muscle & Nerve. 48: 994-5. PMID 23873540 DOI: 10.1002/Mus.23958  0.01
2013 Fratta P, Poulter M, Lashley T, Rohrer JD, Polke JM, Beck J, Ryan N, Hensman D, Mizielinska S, Waite AJ, Lai MC, Gendron TF, Petrucelli L, Fisher EM, Revesz T, et al. Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia. Acta Neuropathologica. 126: 401-9. PMID 23818065 DOI: 10.1007/S00401-013-1147-0  0.01
2013 Rudick RA, Fisher E. Preventing brain atrophy should be the gold standard of effective therapy in MS (after the first year of treatment): Yes. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1003-4. PMID 23818018 DOI: 10.1177/1352458513482385  0.01
2013 Fisher E, Reich DS. Imaging new lesions: enhancing our understanding of multiple sclerosis pathogenesis. Neurology. 81: 202-3. PMID 23761620 DOI: 10.1212/Wnl.0B013E31829C01Da  0.01
2013 Saccon RA, Bunton-Stasyshyn RK, Fisher EM, Fratta P. Is SOD1 loss of function involved in amyotrophic lateral sclerosis? Brain : a Journal of Neurology. 136: 2342-58. PMID 23687121 DOI: 10.1093/Brain/Awt097  0.01
2013 Erbayat Altay E, Fisher E, Jones SE, Hara-Cleaver C, Lee JC, Rudick RA. Reliability of classifying multiple sclerosis disease activity using magnetic resonance imaging in a multiple sclerosis clinic. Jama Neurology. 70: 338-44. PMID 23599930 DOI: 10.1001/2013.Jamaneurol.211  0.01
2013 Gribble SM, Wiseman FK, Clayton S, Prigmore E, Langley E, Yang F, Maguire S, Fu B, Rajan D, Sheppard O, Scott C, Hauser H, Stephens PJ, Stebbings LA, Ng BL, ... Fisher EM, et al. Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome. Plos One. 8: e60482. PMID 23596509 DOI: 10.1371/Journal.Pone.0060482  0.01
2013 Thorne T, Fratta P, Hanna MG, Cortese A, Plagnol V, Fisher EM, Stumpf MP. Graphical modelling of molecular networks underlying sporadic inclusion body myositis. Molecular Biosystems. 9: 1736-42. PMID 23595110 DOI: 10.1039/C3Mb25497F  0.01
2013 Ritchie BJ, Smolski WC, Montgomery ER, Fisher ES, Choi TY, Olson CM, Foster LA, Meigs TE. Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling. Journal of Molecular Signaling. 8: 3. PMID 23531275 DOI: 10.1186/1750-2187-8-3  0.01
2013 McGoldrick P, Joyce PI, Fisher EM, Greensmith L. Rodent models of amyotrophic lateral sclerosis. Biochimica Et Biophysica Acta. 1832: 1421-36. PMID 23524377 DOI: 10.1016/J.Bbadis.2013.03.012  0.01
2013 Bermel RA, You X, Foulds P, Hyde R, Simon JH, Fisher E, Rudick RA. Predictors of long-term outcome in multiple sclerosis patients treated with interferon β. Annals of Neurology. 73: 95-103. PMID 23378325 DOI: 10.1002/ana.23758  0.01
2013 Ahmed MM, Dhanasekaran AR, Tong S, Wiseman FK, Fisher EM, Tybulewicz VL, Gardiner KJ. Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Human Molecular Genetics. 22: 1709-24. PMID 23349361 DOI: 10.1093/Hmg/Ddt017  0.01
2013 Chen JT, Easley K, Schneider C, Nakamura K, Kidd GJ, Chang A, Staugaitis SM, Fox RJ, Fisher E, Arnold DL, Trapp BD. Clinically feasible MTR is sensitive to cortical demyelination in MS. Neurology. 80: 246-52. PMID 23269598 DOI: 10.1212/Wnl.0B013E31827Deb99  0.01
2013 Fratta P, Malik B, Gray A, La Spada AR, Hanna MG, Fisher EM, Greensmith L. FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. Neurobiology of Aging. 34: 1516.e17-9. PMID 23062703 DOI: 10.1016/J.Neurobiolaging.2012.09.008  0.01
2012 Fratta P, Mizielinska S, Nicoll AJ, Zloh M, Fisher EM, Parkinson G, Isaacs AM. C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Scientific Reports. 2: 1016. PMID 23264878 DOI: 10.1038/Srep01016  0.01
2012 Geurts JJ, Calabrese M, Fisher E, Rudick RA. Measurement and clinical effect of grey matter pathology in multiple sclerosis. The Lancet. Neurology. 11: 1082-92. PMID 23153407 DOI: 10.1016/S1474-4422(12)70230-2  0.01
2012 Cohen JA, Coles AJ, Arnold DL, Confavreux C, Fox EJ, Hartung HP, Havrdova E, Selmaj KW, Weiner HL, Fisher E, Brinar VV, Giovannoni G, Stojanovic M, Ertik BI, Lake SL, et al. Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial. Lancet (London, England). 380: 1819-28. PMID 23122652 DOI: 10.1016/S0140-6736(12)61769-3  0.01
2012 Coles AJ, Twyman CL, Arnold DL, Cohen JA, Confavreux C, Fox EJ, Hartung HP, Havrdova E, Selmaj KW, Weiner HL, Miller T, Fisher E, Sandbrink R, Lake SL, Margolin DH, et al. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet (London, England). 380: 1829-39. PMID 23122650 DOI: 10.1016/S0140-6736(12)61768-1  0.01
2012 Fisher E, Benedict RH. Correlation of cognitive impairment and thalamic atrophy in MS: for men only? Neurology. 79: 1748-9. PMID 23019258 DOI: 10.1212/WNL.0b013e31827040b5  0.01
2012 Grizenkova J, Akhtar S, Hummerich H, Tomlinson A, Asante EA, Wenborn A, Fizet J, Poulter M, Wiseman FK, Fisher EM, Tybulewicz VL, Brandner S, Collinge J, Lloyd SE. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 13722-7. PMID 22869728 DOI: 10.1073/Pnas.1208917109  0.01
2012 Rishal I, Kam N, Perry RB, Shinder V, Fisher EM, Schiavo G, Fainzilber M. A motor-driven mechanism for cell-length sensing. Cell Reports. 1: 608-16. PMID 22773964 DOI: 10.1016/J.Celrep.2012.05.013  0.01
2012 Wiggins LM, Kuta A, Stevens JC, Fisher EM, von Bartheld CS. A novel phenotype for the dynein heavy chain mutation Loa: altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons. The Journal of Comparative Neurology. 520: 2757-73. PMID 22684941 DOI: 10.1002/Cne.23085  0.01
2012 Ingram CJ, Weale ME, Plaster CA, Morrison KE, Goodall EF, Pall HS, Beck M, Jablonka S, Sendtner M, Fisher EM, Bradman N, KasperavičiÅ«tÄ— D. Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 341-6. PMID 22409358 DOI: 10.3109/17482968.2012.654394  0.01
2012 Ghazi-Noori S, Froud KE, Mizielinska S, Powell C, Smidak M, Fernandez de Marco M, O'Malley C, Farmer M, Parkinson N, Fisher EM, Asante EA, Brandner S, Collinge J, Isaacs AM. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain : a Journal of Neurology. 135: 819-32. PMID 22366797 DOI: 10.1093/Brain/Aws006  0.01
2012 Sheppard O, Wiseman FK, Ruparelia A, Tybulewicz VL, Fisher EM. Mouse models of aneuploidy. Thescientificworldjournal. 2012: 214078. PMID 22262951 DOI: 10.1100/2012/214078  0.01
2012 Devoy A, Bunton-Stasyshyn RK, Tybulewicz VL, Smith AJ, Fisher EM. Genomically humanized mice: technologies and promises. Nature Reviews. Genetics. 13: 14-20. PMID 22179716 DOI: 10.1038/Nrg3116  0.01
2012 Sheppard O, Plattner F, Rubin A, Slender A, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM, Wiseman FK. Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiology of Aging. 33: 828.e31-44. PMID 21843906 DOI: 10.1016/J.Neurobiolaging.2011.06.025  0.01
2011 Huvenne VA, Tyler PA, Masson DG, Fisher EH, Hauton C, Hühnerbach V, Le Bas TP, Wolff GA. A picture on the wall: innovative mapping reveals cold-water coral refuge in submarine canyon. Plos One. 6: e28755. PMID 22194903 DOI: 10.1371/journal.pone.0028755  0.01
2011 Moll NM, Rietsch AM, Thomas S, Ransohoff AJ, Lee JC, Fox R, Chang A, Ransohoff RM, Fisher E. Multiple sclerosis normal-appearing white matter: pathology-imaging correlations. Annals of Neurology. 70: 764-73. PMID 22162059 DOI: 10.1002/ana.22521  0.01
2011 Filippi M, Rocca MA, De Stefano N, Enzinger C, Fisher E, Horsfield MA, Inglese M, Pelletier D, Comi G. Magnetic resonance techniques in multiple sclerosis: the present and the future. Archives of Neurology. 68: 1514-20. PMID 22159052 DOI: 10.1001/archneurol.2011.914  0.01
2011 Banerjee S, Paik R, Mino RE, Blauth K, Fisher ES, Madden VJ, Fanning AS, Bhat MA. A Laminin G-EGF-Laminin G module in Neurexin IV is essential for the apico-lateral localization of Contactin and organization of septate junctions. Plos One. 6: e25926. PMID 22022470 DOI: 10.1371/Journal.Pone.0025926  0.01
2011 Lana-Elola E, Watson-Scales SD, Fisher EM, Tybulewicz VL. Down syndrome: searching for the genetic culprits. Disease Models & Mechanisms. 4: 586-95. PMID 21878459 DOI: 10.1242/Dmm.008078  0.01
2011 Joyce PI, Fratta P, Fisher EM, Acevedo-Arozena A. SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 420-48. PMID 21706386 DOI: 10.1007/S00335-011-9339-1  0.01
2011 Wolff GA, Billett DS, Bett BJ, Holtvoeth J, FitzGeorge-Balfour T, Fisher EH, Cross I, Shannon R, Salter I, Boorman B, King NJ, Jamieson A, Chaillan F. The effects of natural iron fertilisation on deep-sea ecology: the Crozet Plateau, Southern Indian Ocean. Plos One. 6: e20697. PMID 21695118 DOI: 10.1371/journal.pone.0020697  0.01
2011 Rudick RA, Rani MR, Xu Y, Lee JC, Na J, Shrock J, Josyula A, Fisher E, Ransohoff RM. Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis. Plos One. 6: e19262. PMID 21602934 DOI: 10.1371/journal.pone.0019262  0.01
2011 Acevedo-Arozena A, Kalmar B, Essa S, Ricketts T, Joyce P, Kent R, Rowe C, Parker A, Gray A, Hafezparast M, Thorpe JR, Greensmith L, Fisher EM. A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. Disease Models & Mechanisms. 4: 686-700. PMID 21540242 DOI: 10.1242/Dmm.007237  0.01
2011 Banks GT, Haas MA, Line S, Shepherd HL, Alqatari M, Stewart S, Rishal I, Philpott A, Kalmar B, Kuta A, Groves M, Parkinson N, Acevedo-Arozena A, Brandner S, Bannerman D, ... Fisher EM, et al. Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5483-94. PMID 21471385 DOI: 10.1523/Jneurosci.5244-10.2011  0.01
2011 Stevens JC, Fisher EM, Mead S. How does the genetic assassin select its neuronal target? Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 139-47. PMID 21373885 DOI: 10.1007/S00335-011-9319-5  0.01
2011 Cleary JO, Wiseman FK, Norris FC, Price AN, Choy M, Tybulewicz VL, Ordidge RJ, Brandner S, Fisher EM, Lythgoe MF. Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. Neuroimage. 56: 974-83. PMID 21310249 DOI: 10.1016/J.Neuroimage.2011.01.082  0.01
2011 Duchon A, Pothion S, Brault V, Sharp AJ, Tybulewicz VL, Fisher EM, Herault Y. The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome. Behavioural Brain Research. 217: 271-81. PMID 21047530 DOI: 10.1016/J.Bbr.2010.10.023  0.01
2011 Nakamura K, Fox R, Fisher E. CLADA: cortical longitudinal atrophy detection algorithm. Neuroimage. 54: 278-89. PMID 20674750 DOI: 10.1016/j.neuroimage.2010.07.052  0.01
2010 Ruparelia A, Wiseman F, Sheppard O, Tybulewicz VL, Fisher EM. Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21. Journal of Biomedical Research. 24: 87-99. PMID 23554618 DOI: 10.1016/S1674-8301(10)60016-4  0.01
2010 Deng W, Garrett C, Dombert B, Soura V, Banks G, Fisher EM, van der Brug MP, Hafezparast M. Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions. The Journal of Biological Chemistry. 285: 39922-34. PMID 20889981 DOI: 10.1074/Jbc.M110.178087  0.01
2010 Fisher E. Food safety crises as crises in administrative constitutionalism Health Matrix (Cleveland, Ohio : 1991). 20: 55-91. PMID 20862925  0.01
2010 Wiseman FK, Sheppard O, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM. Generation of a panel of antibodies against proteins encoded on human chromosome 21. Journal of Negative Results in Biomedicine. 9: 7. PMID 20727138 DOI: 10.1186/1477-5751-9-7  0.01
2010 Kuta A, Deng W, Morsi El-Kadi A, Banks GT, Hafezparast M, Pfister KK, Fisher EM. Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts. Plos One. 5: e11682. PMID 20657784 DOI: 10.1371/Journal.Pone.0011682  0.01
2010 Dunlevy L, Bennett M, Slender A, Lana-Elola E, Tybulewicz VL, Fisher EM, Mohun T. Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse. Cardiovascular Research. 88: 287-95. PMID 20558441 DOI: 10.1093/Cvr/Cvq193  0.01
2010 Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, ... Fisher EM, et al. Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. Nature. 465: 813-7. PMID 20535211 DOI: 10.1038/Nature09106  0.01
2010 Chia R, Tattum MH, Jones S, Collinge J, Fisher EM, Jackson GS. Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis. Plos One. 5: e10627. PMID 20498711 DOI: 10.1371/Journal.Pone.0010627  0.01
2010 Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, Dickson DW, Rademakers R, ... ... Fisher EM, et al. FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathologica. 120: 33-41. PMID 20490813 DOI: 10.1007/S00401-010-0698-6  0.01
2010 van de Leemput J, Wavrant-De Vrièze F, Rafferty I, Bras JM, Giunti P, Fisher EM, Hardy JA, Singleton AB, Houlden H. Sequencing analysis of the ITPR1 gene in a pure autosomal dominant spinocerebellar ataxia series. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 771-3. PMID 20437544 DOI: 10.1002/Mds.22970  0.01
2010 El-Kadi AM, Bros-Facer V, Deng W, Philpott A, Stoddart E, Banks G, Jackson GS, Fisher EM, Duchen MR, Greensmith L, Moore AL, Hafezparast M. The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease. The Journal of Biological Chemistry. 285: 18627-39. PMID 20382740 DOI: 10.1074/Jbc.M110.129320  0.01
2010 Radue EW, Stuart WH, Calabresi PA, Confavreux C, Galetta SL, Rudick RA, Lublin FD, Weinstock-Guttman B, Wynn DR, Fisher E, Papadopoulou A, Lynn F, Panzara MA, Sandrock AW. Natalizumab plus interferon beta-1a reduces lesion formation in relapsing multiple sclerosis. Journal of the Neurological Sciences. 292: 28-35. PMID 20236661 DOI: 10.1016/J.Jns.2010.02.012  0.01
2010 Urwin H, Authier A, Nielsen JE, Metcalf D, Powell C, Froud K, Malcolm DS, Holm I, Johannsen P, Brown J, Fisher EM, van der Zee J, Bruyland M, Van Broeckhoven C, et al. Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations. Human Molecular Genetics. 19: 2228-38. PMID 20223751 DOI: 10.1093/Hmg/Ddq100  0.01
2010 Stevens JC, Chia R, Hendriks WT, Bros-Facer V, van Minnen J, Martin JE, Jackson GS, Greensmith L, Schiavo G, Fisher EM. Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS). Plos One. 5: e9541. PMID 20221404 DOI: 10.1371/Journal.Pone.0009541  0.01
2010 Miller G, Neilan M, Chia R, Gheryani N, Holt N, Charbit A, Wells S, Tucci V, Lalanne Z, Denny P, Fisher EM, Cheeseman M, Askew GN, Dear TN. ENU mutagenesis reveals a novel phenotype of reduced limb strength in mice lacking fibrillin 2. Plos One. 5: e9137. PMID 20161761 DOI: 10.1371/Journal.Pone.0009137  0.01
2010 Alford KA, Slender A, Vanes L, Li Z, Fisher EM, Nizetic D, Orkin SH, Roberts I, Tybulewicz VL. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. Blood. 115: 2928-37. PMID 20154221 DOI: 10.1182/Blood-2009-06-227629  0.01
2009 Rudick RA, Fisher E. Do interferon beta-1b and glatiramer acetate grow brain? The Lancet. Neurology. 8: 1085-6; author reply. PMID 19909906 DOI: 10.1016/S1474-4422(09)70312-6  0.01
2009 Fisher EMC, Lana-Elola E, Watson SD, Vassiliou G, Tybulewicz VLJ. New approaches for modelling sporadic genetic disease in the mouse Dmm Disease Models and Mechanisms. 2: 446-453. PMID 19726804 DOI: 10.1242/Dmm.001644  0.01
2009 Banks GT, Bros-Facer V, Williams HP, Chia R, Achilli F, Bryson JB, Greensmith L, Fisher EM. Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1(G93A) motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice. Plos One. 4: e6218. PMID 19593442 DOI: 10.1371/Journal.Pone.0006218  0.01
2009 Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, ... ... Fisher EM, et al. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms. 2: 359-73. PMID 19470612 DOI: 10.1242/Dmm.002527  0.01
2009 Becker EB, Oliver PL, Glitsch MD, Banks GT, Achilli F, Hardy A, Nolan PM, Fisher EM, Davies KE. A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 6706-11. PMID 19351902 DOI: 10.1073/Pnas.0810599106  0.01
2009 Wiseman FK, Alford KA, Tybulewicz VL, Fisher EM. Down syndrome--recent progress and future prospects. Human Molecular Genetics. 18: R75-83. PMID 19297404 DOI: 10.1093/Hmg/Ddp010  0.01
2009 Rudick RA, Fisher E. Brain atrophy as an outcome measure for multiple sclerosis clinical trials: a "no-brainer"? Neurology. 72: 586-7. PMID 19221291 DOI: 10.1212/01.Wnl.0000342478.46908.79  0.01
2009 Need AC, Ge D, Weale ME, Maia J, Feng S, Heinzen EL, Shianna KV, Yoon W, KasperaviciÅ«te D, Gennarelli M, Strittmatter WJ, Bonvicini C, Rossi G, Jayathilake K, Cola PA, ... ... Fisher EM, et al. A genome-wide investigation of SNPs and CNVs in schizophrenia. Plos Genetics. 5: e1000373. PMID 19197363 DOI: 10.1371/Journal.Pgen.1000373  0.01
2009 Chiò A, Schymick JC, Restagno G, Scholz SW, Lombardo F, Lai SL, Mora G, Fung HC, Britton A, Arepalli S, Gibbs JR, Nalls M, Berger S, Kwee LC, Oddone EZ, ... ... Fisher EM, et al. A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 18: 1524-32. PMID 19193627 DOI: 10.1093/Hmg/Ddp059  0.01
2009 Galante M, Jani H, Vanes L, Daniel H, Fisher EM, Tybulewicz VL, Bliss TV, Morice E. Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. Human Molecular Genetics. 18: 1449-63. PMID 19181682 DOI: 10.1093/Hmg/Ddp055  0.01
2009 Moll NM, Cossoy MB, Fisher E, Staugaitis SM, Tucky BH, Rietsch AM, Chang A, Fox RJ, Trapp BD, Ransohoff RM. Imaging correlates of leukocyte accumulation and CXCR4/CXCL12 in multiple sclerosis. Archives of Neurology. 66: 44-53. PMID 19139298 DOI: 10.1001/Archneurol.2008.512  0.01
2009 Rudick RA, Lee JC, Nakamura K, Fisher E. Gray matter atrophy correlates with MS disability progression measured with MSFC but not EDSS. Journal of the Neurological Sciences. 282: 106-11. PMID 19100997 DOI: 10.1016/j.jns.2008.11.018  0.01
2009 Bermel RA, Fisher E, Cohen JA. The use of MR imaging as an outcome measure in multiple sclerosis clinical trials. Neuroimaging Clinics of North America. 18: 687-701, xi. PMID 19068409 DOI: 10.1016/j.nic.2008.06.008  0.01
2009 Wang Y, Mulligan C, Denyer G, Delom F, Dagna-Bricarelli F, Tybulewicz VL, Fisher EM, Griffiths WJ, Nizetic D, Groet J. Quantitative proteomics characterization of a mouse embryonic stem cell model of Down syndrome. Molecular & Cellular Proteomics : McP. 8: 585-95. PMID 19001410 DOI: 10.1074/Mcp.M800256-Mcp200  0.01
2008 Nakamura K, Fisher E. Segmentation of brain magnetic resonance images for measurement of gray matter atrophy in multiple sclerosis patients. Neuroimage. 44: 769-76. PMID 19007895 DOI: 10.1016/j.neuroimage.2008.09.059  0.01
2008 Wilson MD, Barbosa-Morais NL, Schmidt D, Conboy CM, Vanes L, Tybulewicz VL, Fisher EM, Tavaré S, Odom DT. Species-specific transcription in mice carrying human chromosome 21. Science (New York, N.Y.). 322: 434-8. PMID 18787134 DOI: 10.1126/Science.1160930  0.01
2008 Canzonetta C, Mulligan C, Deutsch S, Ruf S, O'Doherty A, Lyle R, Borel C, Lin-Marq N, Delom F, Groet J, Schnappauf F, De Vita S, Averill S, Priestley JV, Martin JE, ... ... Fisher EM, et al. DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. American Journal of Human Genetics. 83: 388-400. PMID 18771760 DOI: 10.1016/J.Ajhg.2008.08.012  0.01
2008 Fisher E, Lee JC, Nakamura K, Rudick RA. Gray matter atrophy in multiple sclerosis: a longitudinal study. Annals of Neurology. 64: 255-65. PMID 18661561 DOI: 10.1002/ana.21436  0.01
2008 Morice E, Andreae LC, Cooke SF, Vanes L, Fisher EM, Tybulewicz VL, Bliss TV. Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 492-500. PMID 18626093 DOI: 10.1101/Lm.969608  0.01
2008 Banks GT, Kuta A, Isaacs AM, Fisher EMC. TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander Mammalian Genome. 19: 299-305. PMID 18592312 DOI: 10.1007/S00335-008-9117-X  0.01
2008 Young EA, Fowler CD, Kidd GJ, Chang A, Rudick R, Fisher E, Trapp BD. Imaging correlates of decreased axonal Na+/K+ ATPase in chronic multiple sclerosis lesions. Annals of Neurology. 63: 428-35. PMID 18438950 DOI: 10.1002/Ana.21381  0.01
2008 Banks GT, Fisher EM. Cytoplasmic dynein could be key to understanding neurodegeneration. Genome Biology. 9: 214. PMID 18373888 DOI: 10.1186/Gb-2008-9-3-214  0.01
2008 van der Zee J, Urwin H, Engelborghs S, Bruyland M, Vandenberghe R, Dermaut B, De Pooter T, Peeters K, Santens P, De Deyn PP, Fisher EM, Collinge J, Isaacs AM, Van Broeckhoven C. CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro. Human Molecular Genetics. 17: 313-22. PMID 17956895 DOI: 10.1093/Hmg/Ddm309  0.01
2007 Mensah A, Mulligan C, Linehan J, Ruf S, O'Doherty A, Grygalewicz B, Shipley J, Groet J, Tybulewicz V, Fisher E, Brandner S, Nizetic D. An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model. Bmc Developmental Biology. 7: 131. PMID 18047653 DOI: 10.1186/1471-213X-7-131  0.01
2007 Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A. Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. The Journal of Cell Biology. 179: 485-500. PMID 17984323 DOI: 10.1083/Jcb.200702115  0.01
2007 Stevens JC, Banks GT, Festing MF, Fisher EM. Quiet mutations in inbred strains of mice. Trends in Molecular Medicine. 13: 512-9. PMID 17981508 DOI: 10.1016/J.Molmed.2007.10.001  0.01
2007 van de Leemput J, Chandran J, Knight MA, Holtzclaw LA, Scholz S, Cookson MR, Houlden H, Gwinn-Hardy K, Fung HC, Lin X, Hernandez D, Simon-Sanchez J, Wood NW, Giunti P, Rafferty I, ... ... Fisher EM, et al. Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. Plos Genetics. 3: e108. PMID 17590087 DOI: 10.1371/Journal.Pgen.0030108  0.01
2007 Bowen S, Ateh DD, Deinhardt K, Bird MM, Price KM, Baker CS, Robson JC, Swash M, Shamsuddin W, Kawar S, El-Tawil T, Roos J, Hoyle A, Nickols CD, Knowles CH, ... ... Fisher EM, et al. The phagocytic capacity of neurones. The European Journal of Neuroscience. 25: 2947-55. PMID 17561810 DOI: 10.1111/J.1460-9568.2007.05554.X  0.01
2007 Hough TA, Polewski M, Johnson K, Cheeseman M, Nolan PM, Vizor L, Rastan S, Boyde A, Pritzker K, Hunter AJ, Fisher EM, Terkeltaub R, Brown SD. Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1397-407. PMID 17539739 DOI: 10.1359/Jbmr.070515  0.01
2007 Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, ... ... Fisher EM, et al. Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 130: 2292-301. PMID 17439985 DOI: 10.1093/Brain/Awm055  0.01
2007 Fisher E, Chang A, Fox RJ, Tkach JA, Svarovsky T, Nakamura K, Rudick RA, Trapp BD. Imaging correlates of axonal swelling in chronic multiple sclerosis brains. Annals of Neurology. 62: 219-28. PMID 17427920 DOI: 10.1002/ana.21113  0.01
2007 Rowe J, Kusel M, Holt BJ, Suriyaarachchi D, Serralha M, Hollams E, Yerkovich ST, Subrata LS, Ladyman C, Sadowska A, Gillett J, Fisher E, Loh R, Soderstrom L, Ahlstedt S, et al. Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort. The Journal of Allergy and Clinical Immunology. 119: 1164-73. PMID 17412403 DOI: 10.1016/j.jaci.2007.02.016  0.01
2006 Tybulewicz VL, Fisher EM. New techniques to understand chromosome dosage: mouse models of aneuploidy. Human Molecular Genetics. 15: R103-9. PMID 16987872 DOI: 10.1093/Hmg/Ddl179  0.01
2006 Rudick RA, Lee JC, Simon J, Fisher E. Significance of T2 lesions in multiple sclerosis: A 13-year longitudinal study. Annals of Neurology. 60: 236-42. PMID 16786526 DOI: 10.1002/ana.20883  0.01
2006 Shah PR, Ahmad-Annuar A, Ahmadi KR, Russ C, Sapp PC, Horvitz HR, Brown RH, Goldstein DB, Fisher EM. No association of DYNC1H1 with sporadic ALS in a case-control study of a northern European derived population: a tagging SNP approach. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 7: 46-56. PMID 16546759 DOI: 10.1080/14660820500397057  0.01
2006 Pfister KK, Shah PR, Hummerich H, Russ A, Cotton J, Annuar AA, King SM, Fisher EMC. Genetic analysis of the cytoplasmic dynein subunit families Plos Genetics. 2: e1. PMID 16440056 DOI: 10.1371/Journal.Pgen.0020001  0.01
2006 Rowe J, Yerkovich ST, Richmond P, Suriyaarachchi D, Fisher E, Feddema L, Loh R, Sly PD, Holt PG. Th2-associated local reactions to the acellular diphtheria-tetanus-pertussis vaccine in 4- to 6-year-old children. Infection and Immunity. 73: 8130-5. PMID 16299307 DOI: 10.1128/IAI.73.12.8130-8135.2005  0.01
2005 Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB. Cytoplasmic dynein nomenclature. The Journal of Cell Biology. 171: 411-3. PMID 16260502 DOI: 10.1083/Jcb.200508078  0.01
2005 Chia R, Achilli F, Festing MF, Fisher EM. The origins and uses of mouse outbred stocks. Nature Genetics. 37: 1181-6. PMID 16254564 DOI: 10.1038/Ng1665  0.01
2005 O'Doherty A, Ruf S, Mulligan C, Hildreth V, Errington ML, Cooke S, Sesay A, Modino S, Vanes L, Hernandez D, Linehan JM, Sharpe PT, Brandner S, Bliss TV, Henderson DJ, ... ... Fisher EM, et al. An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science (New York, N.Y.). 309: 2033-7. PMID 16179473 DOI: 10.1126/science.1114535  0.01
2005 Bermel RA, Puli SR, Rudick RA, Weinstock-Guttman B, Fisher E, Munschauer FE, Bakshi R. Prediction of longitudinal brain atrophy in multiple sclerosis by gray matter magnetic resonance imaging T2 hypointensity. Archives of Neurology. 62: 1371-6. PMID 16157744 DOI: 10.1001/Archneur.62.9.1371  0.01
2005 Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H, Nielsen JE, Hodges JR, Spillantini MG, Thusgaard T, Brandner S, Brun A, Rossor MN, Gade A, Johannsen P, ... ... Fisher EM, et al. Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nature Genetics. 37: 806-8. PMID 16041373 DOI: 10.1038/Ng1609  0.01
2005 Achilli F, Boyle S, Kieran D, Chia R, Hafezparast M, Martin JE, Schiavo G, Greensmith L, Bickmore W, Fisher EM. The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 6: 111-4. PMID 16036435 DOI: 10.1080/14660820510035351  0.01
2005 Kieran D, Hafezparast M, Bohnert S, Dick JR, Martin J, Schiavo G, Fisher EM, Greensmith L. A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. The Journal of Cell Biology. 169: 561-7. PMID 15911875 DOI: 10.1083/Jcb.200501085  0.01
2005 Fox RJ, Fisher E, Tkach J, Lee JC, Cohen JA, Rudick RA. Brain atrophy and magnetization transfer ratio following methylprednisolone in multiple sclerosis: short-term changes and long-term implications. Multiple Sclerosis (Houndmills, Basingstoke, England). 11: 140-5. PMID 15794385 DOI: 10.1191/1352458505ms1142oa  0.01
2005 Marrie RA, Fisher E, Miller DM, Lee JC, Rudick RA. Association of fatigue and brain atrophy in multiple sclerosis. Journal of the Neurological Sciences. 228: 161-6. PMID 15694198 DOI: 10.1016/j.jns.2004.11.046  0.01
2005 Weisse CS, Foster KK, Fisher EA. The influence of experimenter gender and race on pain reporting: does racial or gender concordance matter? Pain Medicine (Malden, Mass.). 6: 80-7. PMID 15669953 DOI: 10.1111/j.1526-4637.2005.05004.x  0.01
2005 Meier DS, Fisher E. Atlas-based anatomic labeling in neurodegenerative disease via structure-driven atlas warping. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 15: 16-26. PMID 15574570 DOI: 10.1177/1051228404269493  0.01
2005 Hafezparast M, Brandner S, Linehan J, Martin JE, Collinge J, Fisher EM. Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. Biochemical and Biophysical Research Communications. 326: 18-22. PMID 15567146 DOI: 10.1016/J.Bbrc.2004.10.206  0.01
2004 Tsipouri V, Curtin JA, Nolan PM, Vizor L, Parsons CA, Clapham CM, Latham ID, Rooke LJ, Martin JE, Peters J, Hunter AJ, Rogers D, Rastan S, Brown SD, Fisher EM, et al. Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse. Comparative and Functional Genomics. 5: 123-7. PMID 18629060 DOI: 10.1002/Cfg.382  0.01
2004 Rastan S, Hough T, Kierman A, Hardisty R, Erven A, Gray IC, Voeling S, Isaacs A, Tsai H, Strivens M, Washbourne R, Thornton C, Greenaway S, Hewitt M, McCormick S, ... ... Fisher EM, et al. Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders. Genetica. 122: 47-9. PMID 15619960 DOI: 10.1007/S10709-004-1930-X  0.01
2004 Rudick RA, Lee JC, Simon J, Ransohoff RM, Fisher E. Defining interferon beta response status in multiple sclerosis patients. Annals of Neurology. 56: 548-55. PMID 15389896 DOI: 10.1002/ana.20224  0.01
2004 Brown J, Gydesen S, Johannsen P, Gade A, Skibinski G, Chakrabarti L, Brun A, Spillantini M, Yancopoulou D, Thusgaard T, Sorensen A, Fisher E, Collinge J. Frontotemporal dementia linked to chromosome 3. Dementia and Geriatric Cognitive Disorders. 17: 274-6. PMID 15178935 DOI: 10.1159/000077153  0.01
2004 Lloyd SE, Thompson SR, Beck JA, Linehan JM, Wadsworth JD, Brandner S, Collinge J, Fisher EM. Identification and characterization of a novel mouse prion gene allele. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 383-9. PMID 15170227 DOI: 10.1007/S00335-004-3041-5  0.01
2003 Hafezparast M, Ahmad-Annuar A, Hummerich H, Shah P, Ford M, Baker C, Bowen S, Martin JE, Fisher EM. Paradigms for the identification of new genes in motor neuron degeneration. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 4: 249-57. PMID 14753659 DOI: 10.1080/14660820310016084  0.01
2003 Hardmeier M, Wagenpfeil S, Freitag P, Fisher E, Rudick RA, Kooijmans-Coutinho M, Clanet M, Radue EW, Kappos L. Atrophy is detectable within a 3-month period in untreated patients with active relapsing remitting multiple sclerosis. Archives of Neurology. 60: 1736-9. PMID 14676048 DOI: 10.1001/Archneur.60.12.1736  0.01
2003 Doherty AM, Fisher EM. Microcell-mediated chromosome transfer (MMCT): small cells with huge potential. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 583-92. PMID 14629108 DOI: 10.1007/S00335-003-4002-0  0.01
2003 Ahmad-Annuar A, Shah P, Hafezparast M, Hummerich H, Witherden AS, Morrison KE, Shaw PJ, Kirby J, Warner TT, Crosby A, Proukakis C, Wilkinson P, Orrell RW, Bradley L, Martin JE, ... Fisher EM, et al. No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 4: 150-7. PMID 13129801 DOI: 10.1080/14660820310011737  0.01
2003 Ahmad-Annuar A, Tabrizi SJ, Fisher EMC. Mouse models as a tool for understanding neurodegenerative diseases Current Opinion in Neurology. 16: 451-458. PMID 12869802 DOI: 10.1097/01.Wco.0000084221.82329.29  0.01
2003 Curtin JA, Quint E, Tsipouri V, Arkell RM, Cattanach B, Copp AJ, Henderson DJ, Spurr N, Stanier P, Fisher EM, Nolan PM, Steel KP, Brown SD, Gray IC, Murdoch JN. Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Current Biology : Cb. 13: 1129-33. PMID 12842012 DOI: 10.1016/S0960-9822(03)00374-9  0.01
2003 Death AK, Fisher EJ, McGrath KCY, Yue DK. High glucose alters matrix metalloproteinase expression in two key vascular cells: Potential impact on atherosclerosis in diabetes Atherosclerosis. 168: 263-269. PMID 12801609 DOI: 10.1016/S0021-9150(03)00140-0  0.01
2003 Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, ... ... Fisher EM, et al. Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (New York, N.Y.). 300: 808-12. PMID 12730604 DOI: 10.1126/Science.1083129  0.01
2003 Mead S, Stumpf MP, Whitfield J, Beck JA, Poulter M, Campbell T, Uphill JB, Goldstein D, Alpers M, Fisher EM, Collinge J. Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics. Science (New York, N.Y.). 300: 640-3. PMID 12690204 DOI: 10.1126/Science.1083320  0.01
2003 Miller DM, Rudick RA, Baier M, Cutter G, Doughtery DS, Weinstock-Guttman B, Mass MK, Fisher E, Simonian N. Factors that predict health-related quality of life in patients with relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 9: 1-5. PMID 12617260 DOI: 10.1191/1352458503Ms888Oa  0.01
2002 Hafezparast M, Ahmad-Annuar A, Wood NW, Tabrizi SJ, Fisher EMC. Mouse models for neurological disease Lancet Neurology. 1: 215-224. PMID 12849454 DOI: 10.1016/S1474-4422(02)00100-X  0.01
2002 Lloyd SE, Uphill JB, Targonski PV, Fisher EM, Collinge J. Identification of genetic loci affecting mouse-adapted bovine spongiform encephalopathy incubation time in mice. Neurogenetics. 4: 77-81. PMID 12481985 DOI: 10.1007/S10048-002-0133-9  0.01
2002 Hanekamp T, Thorsness MK, Rebbapragada I, Fisher EM, Seebart C, Darland MR, Coxbill JA, Updike DL, Thorsness PE. Maintenance of mitochondrial morphology is linked to maintenance of the mitochondrial genome in Saccharomyces cerevisiae. Genetics. 162: 1147-56. PMID 12454062  0.01
2002 Hough TA, Nolan PM, Tsipouri V, Toye AA, Gray IC, Goldsworthy M, Moir L, Cox RD, Clements S, Glenister PH, Wood J, Selley RL, Strivens MA, Vizor L, McCormack SL, ... ... Fisher EM, et al. Novel phenotypes identified by plasma biochemical screening in the mouse. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 595-602. PMID 12420138 DOI: 10.1007/s00335-002-2188-1  0.01
2002 Ramos VC, Vidal-Taboada J, Bergoñon S, Egeo A, Fisher EM, Scartezzini P, Oliva R. Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21. Biochimica Et Biophysica Acta. 1577: 377-83. PMID 12359327 DOI: 10.1016/S0167-4781(02)00421-9  0.01
2002 Fox RJ, Fisher E, Rudick R. Disease modifying therapies in multiple sclerosis. Neurology. 59: 471-2; author reply . PMID 12177396 DOI: 10.1212/Wnl.59.3.471  0.01
2002 Hafezparast M, Ball S, Nicholson SJ, Witherden A, Arac D, Broadway N, Saggerson D, Cooper E, Naase M, Gokhale S, Quant P, Lascelles C, Nickols C, Baker CS, Peters J, ... ... Fisher EM, et al. A new mouse mutant, skijumper. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 359-364. PMID 12152619 DOI: 10.1007/Pl00021068  0.01
2002 Witherden AS, Hafezparast M, Nicholson SJ, Ahmad-Annuar A, Bermingham N, Arac D, Rankin J, Iravani M, Ball S, Peters J, Martin JE, Huntley D, Hummerich H, Sergot M, Fisher EM. An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation. Gene. 283: 71-82. PMID 11867214 DOI: 10.1016/S0378-1119(01)00853-8  0.01
2002 Meier D, Fisher E. Parameter space warping: shape-based correspondence between morphologically different objects. Ieee Transactions On Medical Imaging. 21: 31-47. PMID 11838662 DOI: 10.1109/42.981232  0.01
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