Year |
Citation |
Score |
2025 |
Yoo J, Lee J, Ahn B, Han J, Lim MH. Multi-target-directed therapeutic strategies for Alzheimer's disease: controlling amyloid-β aggregation, metal ion homeostasis, and enzyme inhibition. Chemical Science. PMID 39810997 DOI: 10.1039/d4sc06762b |
0.556 |
|
2023 |
Nam E, Lin Y, Park J, Do H, Han J, Jeong B, Park S, Lee DY, Kim M, Han J, Baik MH, Lee YH, Lim MH. APP-C31: An Intracellular Promoter of Both Metal-Free and Metal-Bound Amyloid-β Aggregation and Toxicity in Alzheimer's Disease. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2307182. PMID 37949680 DOI: 10.1002/advs.202307182 |
0.816 |
|
2023 |
Han J. Copper trafficking systems in cells: insights into coordination chemistry and toxicity. Dalton Transactions (Cambridge, England : 2003). PMID 37702384 DOI: 10.1039/d3dt02166a |
0.307 |
|
2023 |
Yoo J, Han J, Lim MH. Transition metal ions and neurotransmitters: coordination chemistry and implications for neurodegeneration. Rsc Chemical Biology. 4: 548-563. PMID 37547459 DOI: 10.1039/d3cb00052d |
0.588 |
|
2023 |
Park S, Na C, Han J, Lim MH. Methods for analyzing the coordination and aggregation of metal-amyloid-β. Metallomics : Integrated Biometal Science. PMID 36617236 DOI: 10.1093/mtomcs/mfac102 |
0.75 |
|
2022 |
Han J, Yoon J, Shin J, Nam E, Qian T, Li Y, Park K, Lee SH, Lim MH. Conformational and functional changes of the native neuropeptide somatostatin occur in the presence of copper and amyloid-β. Nature Chemistry. PMID 35817963 DOI: 10.1038/s41557-022-00984-3 |
0.801 |
|
2021 |
Han J, Du Z, Lim MH. Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer's Disease. Accounts of Chemical Research. PMID 34606227 DOI: 10.1021/acs.accounts.1c00457 |
0.822 |
|
2021 |
Nam E, Han J, Choi S, Lim MH. Distinct impact of glycation towards the aggregation and toxicity of murine and human amyloid-β. Chemical Communications (Cambridge, England). PMID 34254069 DOI: 10.1039/d1cc02695j |
0.742 |
|
2020 |
Yi Y, Lin Y, Han J, Lee HJ, Park N, Nam G, Park YS, Lee YH, Lim MH. Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β. Chemical Science. 12: 2456-2466. PMID 34164011 DOI: 10.1039/d0sc04366d |
0.791 |
|
2020 |
Kim M, Kang J, Lee M, Han J, Nam G, Tak E, Kim MS, Lee HJ, Nam E, Park J, Oh SJ, Lee JY, Lee JY, Baik MH, Lim MH. Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia. Journal of the American Chemical Society. PMID 32233474 DOI: 10.1021/Jacs.9B13100 |
0.74 |
|
2020 |
Han J, Lee HJ, Kim KY, Nam G, Chae J, Lim MH. Mechanistic approaches for chemically modifying the coordination sphere of copper-amyloid-β complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32102914 DOI: 10.1073/Pnas.1916944117 |
0.78 |
|
2019 |
Yi Y, Han J, Park MH, Park N, Nam E, Jin HK, Bae JS, Lim MH. Tunable regulatory activities of 1,10-phenanthroline derivatives towards acid sphingomyelinase and Zn(ii)-amyloid-β. Chemical Communications (Cambridge, England). PMID 31042246 DOI: 10.1039/C9Cc01005J |
0.773 |
|
2018 |
Kim MS, Jo TG, Yang M, Han J, Lim MH, Kim C. A fluorescent and colorimetric Schiff base chemosensor for the detection of Zn and Cu: Application in live cell imaging and colorimetric test kit. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 211: 34-43. PMID 30502582 DOI: 10.1016/J.Saa.2018.11.058 |
0.462 |
|
2018 |
Nam E, Derrick JS, Lee S, Kang J, Han J, Lee SJC, Chung SW, Lim MH. Regulatory Activities of Dopamine and Its Derivatives towards Metal-Free and Metal-Induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer's Disease. Acs Chemical Neuroscience. PMID 29782798 DOI: 10.1021/Acschemneuro.8B00122 |
0.828 |
|
2018 |
Jung JM, Kang JH, Han J, Lee H, Lim MH, Kim K, Kim C. A novel “off-on” type fluorescent chemosensor for detection of Zn2+ and its zinc complex for “on-off” fluorescent sensing of sulfide in aqueous solution, in vitro and in vivo Sensors and Actuators B: Chemical. 267: 58-69. DOI: 10.1016/J.Snb.2018.03.063 |
0.556 |
|
2018 |
Yun JY, Jo TG, Han J, Jang HJ, Lim MH, Kim C. A highly sensitive and selective fluorescent chemosensor for the sequential recognition of Zn2+ and S2− in living cells and aqueous media Sensors and Actuators B: Chemical. 255: 3108-3116. DOI: 10.1016/J.Snb.2017.09.136 |
0.516 |
|
2018 |
Kang JH, Han J, Lee H, Lim MH, Kim K, Kim C. A water-soluble fluorescence chemosensor for the sequential detection of Zn2+ and pyrophosphate in living cells and zebrafish Dyes and Pigments. 152: 131-138. DOI: 10.1016/J.Dyepig.2018.01.039 |
0.515 |
|
2017 |
Han J, Lee HJ, Kim KY, Lee SJC, Suh JM, Cho J, Chae J, Lim MH. Tuning Structures and Properties for Developing Novel Chemical Tools toward Distinct Pathogenic Elements in Alzheimer's Disease. Acs Chemical Neuroscience. PMID 29283241 DOI: 10.1021/Acschemneuro.7B00454 |
0.83 |
|
2017 |
Nam E, Han J, Suh JM, Yi Y, Lim MH. Link of impaired metal ion homeostasis to mitochondrial dysfunction in neurons. Current Opinion in Chemical Biology. 43: 8-14. PMID 29100100 DOI: 10.1016/J.Cbpa.2017.09.009 |
0.759 |
|
2017 |
Jo TG, Jung JM, Han J, Lim MH, Kim C. A single fluorescent chemosensor for multiple targets of Cu2+, Fe2+/3+ and Al3+ in living cells and a near-perfect aqueous solution Rsc Advances. 7: 28723-28732. DOI: 10.1039/C7Ra05565J |
0.478 |
|
2017 |
Jeong HY, Lee SY, Han J, Lim MH, Kim C. Thiophene and diethylaminophenol-based “turn-on” fluorescence chemosensor for detection of Al 3+ and F − in a near-perfect aqueous solution Tetrahedron. 73: 2690-2697. DOI: 10.1016/J.Tet.2017.03.069 |
0.466 |
|
2017 |
Jo TG, Bok KH, Han J, Lim MH, Kim C. Colorimetric detection of Fe 3+ and Fe 2+ and sequential fluorescent detection of Al 3+ and pyrophosphate by an imidazole-based chemosensor in a near-perfect aqueous solution Dyes and Pigments. 139: 136-147. DOI: 10.1016/J.Dyepig.2016.11.052 |
0.453 |
|
2016 |
Beck MW, Derrick JS, Kerr RA, Oh SB, Cho WJ, Lee SJ, Ji Y, Han J, Tehrani ZA, Suh N, Kim S, Larsen SD, Kim KS, Lee JY, Ruotolo BT, et al. Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease. Nature Communications. 7: 13115. PMID 27734843 DOI: 10.1038/Ncomms13115 |
0.765 |
|
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