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Hyuck Jin Lee - Publications

Affiliations: 
2015 University of Michigan, Ann Arbor, Ann Arbor, MI 
 2015-2018 Ulsan National Institute of Science and Technology, Ulsan, South Korea 
 2018-2019 Korea Advanced Institute of Science and Technology, Daejeon, South Korea 
 2019- Kongju National University 
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nguyen YT, Kim N, Lee HJ. Regulating Histone Deacetylases and Carbonic Anhydrases by Metal Complexes: A Potent Strategy for Treating Cancers. Discovery Medicine. 36: 2152-2174. PMID 39600271 DOI: 10.24976/Discov.Med.202436190.198  0.313
2023 Nguyen YT, Kim N, Lee HJ. Metal Complexes as Promising Matrix Metalloproteinases Regulators. International Journal of Molecular Sciences. 24. PMID 36674771 DOI: 10.3390/ijms24021258  0.322
2021 Kim N, Lee HJ. Redox-Active Metal Ions and Amyloid-Degrading Enzymes in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 34299316 DOI: 10.3390/ijms22147697  0.503
2020 Yi Y, Lin Y, Han J, Lee HJ, Park N, Nam G, Park YS, Lee YH, Lim MH. Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β. Chemical Science. 12: 2456-2466. PMID 34164011 DOI: 10.1039/d0sc04366d  0.866
2020 Nam G, Hong M, Lee J, Lee HJ, Ji Y, Kang J, Baik MH, Lim MH. Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure-activity relationship. Chemical Science. 11: 10243-10254. PMID 34094290 DOI: 10.1039/d0sc02046j  0.831
2020 Kim N, Lee HJ. Target Enzymes Considered for the Treatment of Alzheimer's Disease and Parkinson's Disease. Biomed Research International. 2020: 2010728. PMID 33224974 DOI: 10.1155/2020/2010728  0.468
2020 Nam G, Ji Y, Lee HJ, Kang J, Yi Y, Kim M, Lin Y, Lee YH, Lim MH. Correction to "Orobol: An Isoflavone Exhibiting Regulatory Multifunctionality against Four Pathological Features of Alzheimer's Disease". Acs Chemical Neuroscience. PMID 32285655 DOI: 10.1021/Acschemneuro.0C00179  0.784
2020 Kim M, Kang J, Lee M, Han J, Nam G, Tak E, Kim MS, Lee HJ, Nam E, Park J, Oh SJ, Lee JY, Lee JY, Baik MH, Lim MH. Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia. Journal of the American Chemical Society. PMID 32233474 DOI: 10.1021/Jacs.9B13100  0.843
2020 Han J, Lee HJ, Kim KY, Nam G, Chae J, Lim MH. Mechanistic approaches for chemically modifying the coordination sphere of copper-amyloid-β complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32102914 DOI: 10.1073/Pnas.1916944117  0.831
2020 Nam G, Hong M, Lee J, Lee HJ, Ji Y, Kang J, Baik M, Lim MH. Multiple Reactivities of Flavonoids towards Pathological Elements in Alzheimer’s Disease: Structure-Activity Relationship Chemical Science. DOI: 10.1039/D0Sc02046J  0.859
2019 Kang J, Nam JS, Lee HJ, Nam G, Rhee HW, Kwon TH, Lim MH. Chemical strategies to modify amyloidogenic peptides using iridium(iii) complexes: coordination and photo-induced oxidation. Chemical Science. 10: 6855-6862. PMID 31391908 DOI: 10.1039/C9Sc00931K  0.828
2019 Lee HJ, Lee YG, Kang J, Yang SH, Kim JH, Ghisaidoobe ABT, Kang HJ, Lee SR, Lim MH, Chung SJ. Correction: Monitoring metal-amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening. Chemical Science. 10: 6390-6392. PMID 31367302 DOI: 10.1039/c9sc90118c  0.78
2019 Nam G, Ji Y, Lee HJ, Kang J, Yi Y, Kim M, Lin Y, Lee YH, Lim MH. Orobol: An Isoflavone with Regulatory Multifunctionality against Four Pathological Factors of Alzheimer's Disease. Acs Chemical Neuroscience. PMID 31199606 DOI: 10.1021/Acschemneuro.9B00232  0.843
2019 Lee HJ, Lee YG, Kang J, Yang SH, Kim JH, Ghisaidoobe ABT, Kang HJ, Lee SR, Lim MH, Chung SJ. Monitoring metal-amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening. Chemical Science. 10: 1000-1007. PMID 30774894 DOI: 10.1039/C8Sc04943B  0.853
2019 Lee M, Kim M, Tikum AF, Lee HJ, Thamilarasan V, Lim MH, Kim J. A near-infrared fluorescent probe for amyloid-β aggregates Dyes and Pigments. 162: 97-103. DOI: 10.1016/J.Dyepig.2018.10.013  0.784
2018 Kim S, Lee HJ, Nam E, Jeong D, Cho J, Lim MH, You Y. Tailoring Hydrophobic Interactions between Probes and Amyloid-β Peptides for Fluorescent Monitoring of Amyloid-β Aggregation. Acs Omega. 3: 5141-5154. PMID 31458729 DOI: 10.1021/acsomega.8b00286  0.734
2018 Savelieff MG, Nam G, Kang J, Lee HJ, Lee M, Lim MH. Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade. Chemical Reviews. PMID 30095897 DOI: 10.1021/Acs.Chemrev.8B00138  0.795
2018 Lee HJ, Savelieff MG, Kang J, Brophy MB, Nakashige TG, Lee SJC, Nolan EM, Lim MH. Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction. Metallomics : Integrated Biometal Science. PMID 30046785 DOI: 10.1039/C8Mt00091C  0.879
2017 Han J, Lee HJ, Kim KY, Lee SJC, Suh JM, Cho J, Chae J, Lim MH. Tuning Structures and Properties for Developing Novel Chemical Tools toward Distinct Pathogenic Elements in Alzheimer's Disease. Acs Chemical Neuroscience. PMID 29283241 DOI: 10.1021/Acschemneuro.7B00454  0.878
2017 Choi TS, Lee HJ, Han JY, Lim MH, Kim HI. Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region. Journal of the American Chemical Society. PMID 28930473 DOI: 10.1021/Jacs.7B08584  0.774
2017 Ji Y, Lee HJ, Kim M, Nam G, Lee SJC, Cho J, Park CM, Lim MH. Strategic Design of 2,2'-Bipyridine Derivatives to Modulate Metal-Amyloid-β Aggregation. Inorganic Chemistry. PMID 28485587 DOI: 10.1021/Acs.Inorgchem.7B00782  0.883
2017 Lee HJ, Korshavn KJ, Nam Y, Kang J, Paul TJ, Kerr RA, Youn IS, Ozbil M, Kim KS, Ruotolo BT, Prabhakar R, Ramamoorthy A, Lim MH. Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 2706-2715. PMID 28004889 DOI: 10.1002/Chem.201605401  0.853
2017 Kang J, Lee SJ, Nam JS, Lee HJ, Kang MG, Korshavn KJ, Kim HT, Cho J, Ramamoorthy A, Rhee HW, Kwon TH, Lim MH. An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 1645-1653. PMID 27862428 DOI: 10.1002/Chem.201604751  0.781
2016 Lee SJC, Choi TS, Lee JW, Lee HJ, Mun DG, Akashi S, Lee SW, Lim MH, Kim HI. Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper. Chemical Science. 7: 5398-5406. PMID 30155193 DOI: 10.1039/C6Sc00153J  0.682
2016 Lee SJ, Nam E, Lee HJ, Savelieff MG, Lim MH. Towards an understanding of amyloid-β oligomers: characterization, toxicity mechanisms, and inhibitors. Chemical Society Reviews. PMID 27878186 DOI: 10.1039/C6Cs00731G  0.849
2016 Lee SJC, Choi TS, Lee JW, Lee HJ, Mun DG, Akashi S, Lee SW, Lim MH, Kim HI. Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper Chemical Science. 7: 5398-5406. DOI: 10.1039/c6sc00153j  0.643
2016 Lee HJ, Kerr RA, Korshavn KJ, Lee J, Kang J, Ramamoorthy A, Ruotolo BT, Lim MH. Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation Inorganic Chemistry Frontiers. 3: 381-392. DOI: 10.1039/C5Qi00219B  0.876
2015 Beck MW, Oh SB, Kerr RA, Lee HJ, Kim SH, Kim S, Jang M, Ruotolo BT, Lee JY, Lim MH. A rationally designed small molecule for identifying an in vivo link between metal-amyloid-β complexes and the pathogenesis of Alzheimer's disease. Chemical Science. 6: 1879-1886. PMID 28706643 DOI: 10.1039/C4Sc03239J  0.842
2015 Derrick JS, Kerr RA, Nam Y, Oh SB, Lee HJ, Earnest KG, Suh N, Peck KL, Ozbil M, Korshavn KJ, Ramamoorthy A, Prabhakar R, Merino EJ, Shearer J, Lee JY, et al. A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms. Journal of the American Chemical Society. 137: 14785-97. PMID 26575890 DOI: 10.1021/Jacs.5B10043  0.69
2015 Kochi A, Lee HJ, Vithanarachchi SM, Padmini V, Allen MJ, Lim MH. Inhibitory Activity of Curcumin Derivatives Towards Metal-Free and Metal-Induced Amyloid-β Aggregation. Current Alzheimer Research. 12: 415-23. PMID 25938870 DOI: 10.2174/1567205012666150504150125  0.865
2014 DeToma AS, Krishnamoorthy J, Nam Y, Lee HJ, Brender JR, Kochi A, Lee D, Onnis V, Congiu C, Manfredini S, Vertuani S, Balboni G, Ramamoorthy A, Lim MH. Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species. Chemical Science. 5: 4851-4862. PMID 25383163 DOI: 10.1039/C4Sc01531B  0.871
2014 Lee HJ, Korshavn KJ, Kochi A, Derrick JS, Lim MH. Cholesterol and metal ions in Alzheimer's disease. Chemical Society Reviews. 43: 6672-82. PMID 24710074 DOI: 10.1039/C4Cs00005F  0.81
2014 Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH. Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease. Journal of the American Chemical Society. 136: 299-310. PMID 24397771 DOI: 10.1021/Ja409801P  0.887
2014 Savelieff MG, Liu Y, Senthamarai RR, Korshavn KJ, Lee HJ, Ramamoorthy A, Lim MH. A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease. Chemical Communications (Cambridge, England). 50: 5301-3. PMID 24326305 DOI: 10.1039/C3Cc48473D  0.819
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