Year |
Citation |
Score |
2018 |
Wang J, Yamamoto T, Bai J, Cox SJ, Korshavn KJ, Monette M, Ramamoorthy A. Real-time monitoring of the aggregation of Alzheimer's amyloid-β viaH magic angle spinning NMR spectroscopy. Chemical Communications (Cambridge, England). 54: 2000-2003. PMID 29411841 DOI: 10.1039/C8Cc00167G |
0.626 |
|
2017 |
Rodriguez Camargo DC, Korshavn KJ, Jussupow A, Raltchev K, Goricanec D, Fleisch M, Sarkar R, Xue K, Aichler M, Mettenleiter G, Walch AK, Camilloni C, Hagn F, Reif B, Ramamoorthy A. Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate. Elife. 6. PMID 29148426 DOI: 10.7554/Elife.31226 |
0.571 |
|
2017 |
Beck MW, Derrick JS, Suh JM, Kim M, Korshavn KJ, Kerr RA, Cho WJ, Larsen SD, Ruotolo BT, Ramamoorthy A, Lim MH. Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease. Chemmedchem. 12: 1828-1838. PMID 28990338 DOI: 10.1002/Cmdc.201700456 |
0.606 |
|
2017 |
Jones MR, Mathieu E, Dyrager C, Faissner S, Vaillancourt Z, Korshavn KJ, Lim MH, Ramamoorthy A, Wee Yong V, Tsutsui S, Stys PK, Storr T. Multi-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's disease. Chemical Science. 8: 5636-5643. PMID 28989601 DOI: 10.1039/C7Sc01269A |
0.654 |
|
2017 |
Korshavn KJ, Satriano C, Lin Y, Zhang R, Dulchavsky M, Bhunia A, Ivanova MI, Lee YH, La Rosa C, Lim MH, Ramamoorthy A. Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β. The Journal of Biological Chemistry. 292: 4638-4650. PMID 28154182 DOI: 10.1074/Jbc.M116.764092 |
0.712 |
|
2017 |
Lee HJ, Korshavn KJ, Nam Y, Kang J, Paul TJ, Kerr RA, Youn IS, Ozbil M, Kim KS, Ruotolo BT, Prabhakar R, Ramamoorthy A, Lim MH. Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 2706-2715. PMID 28004889 DOI: 10.1002/Chem.201605401 |
0.594 |
|
2017 |
Kang J, Lee SJ, Nam JS, Lee HJ, Kang MG, Korshavn KJ, Kim HT, Cho J, Ramamoorthy A, Rhee HW, Kwon TH, Lim MH. An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 1645-1653. PMID 27862428 DOI: 10.1002/Chem.201604751 |
0.528 |
|
2017 |
Beck MW, Derrick JS, Suh J, Kim M, Korshavn KJ, Kerr RA, Cho WJ, Larsen SD, Ruotolo BT, Ramamoorthy A, Lim MH. Front Cover: Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease (ChemMedChem 22/2017) Chemmedchem. 12: 1818-1818. DOI: 10.1002/Cmdc.201700711 |
0.507 |
|
2016 |
Bera S, Korshavn KJ, Kar RK, Lim MH, Ramamoorthy A, Bhunia A. Biophysical insights into the membrane interaction of the core amyloid-forming Aβ40 fragment K16-K28 and its role in the pathogenesis of Alzheimer's disease. Physical Chemistry Chemical Physics : Pccp. 18: 16890-901. PMID 27282693 DOI: 10.1039/C6Cp02023B |
0.568 |
|
2016 |
Jones MR, Dyrager C, Hoarau M, Korshavn KJ, Lim MH, Ramamoorthy A, Storr T. Multifunctional quinoline-triazole derivatives as potential modulators of amyloid-β peptide aggregation. Journal of Inorganic Biochemistry. 158: 131-138. PMID 27133802 DOI: 10.1016/J.Jinorgbio.2016.04.022 |
0.605 |
|
2016 |
Derrick JS, Kerr RA, Korshavn KJ, McLane MJ, Kang J, Nam E, Ramamoorthy A, Ruotolo BT, Lim MH. Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-β, and Oxidative Stress in Alzheimer's Disease. Inorganic Chemistry. 55: 5000-13. PMID 27119456 DOI: 10.1021/Acs.Inorgchem.6B00525 |
0.593 |
|
2016 |
Korshavn KJ, Bhunia A, Lim MH, Ramamoorthy A. Amyloid-β adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation. Chemical Communications (Cambridge, England). 52: 882-5. PMID 26553596 DOI: 10.1039/C5Cc08634E |
0.588 |
|
2016 |
Lee HJ, Kerr RA, Korshavn KJ, Lee J, Kang J, Ramamoorthy A, Ruotolo BT, Lim MH. Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation Inorganic Chemistry Frontiers. 3: 381-392. DOI: 10.1039/C5Qi00219B |
0.623 |
|
2015 |
Korshavn KJ, Jang M, Kwak YJ, Kochi A, Vertuani S, Bhunia A, Manfredini S, Ramamoorthy A, Lim MH. Reactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified Derivatives. Scientific Reports. 5: 17842. PMID 26657338 DOI: 10.1038/Srep17842 |
0.579 |
|
2015 |
Derrick JS, Kerr RA, Nam Y, Oh SB, Lee HJ, Earnest KG, Suh N, Peck KL, Ozbil M, Korshavn KJ, Ramamoorthy A, Prabhakar R, Merino EJ, Shearer J, Lee JY, et al. A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms. Journal of the American Chemical Society. 137: 14785-97. PMID 26575890 DOI: 10.1021/Jacs.5B10043 |
0.613 |
|
2014 |
Lee HJ, Korshavn KJ, Kochi A, Derrick JS, Lim MH. Cholesterol and metal ions in Alzheimer's disease. Chemical Society Reviews. 43: 6672-82. PMID 24710074 DOI: 10.1039/C4Cs00005F |
0.366 |
|
2014 |
Savelieff MG, Liu Y, Senthamarai RR, Korshavn KJ, Lee HJ, Ramamoorthy A, Lim MH. A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease. Chemical Communications (Cambridge, England). 50: 5301-3. PMID 24326305 DOI: 10.1039/C3Cc48473D |
0.685 |
|
2014 |
Beck MW, Pithadia AS, Detoma AS, Korshavn KJ, Lim MH. Ligand Design to Target and Modulate Metal-Protein Interactions in Neurodegenerative Diseases Ligand Design in Medicinal Inorganic Chemistry. 257-286. DOI: 10.1002/9781118697191.ch10 |
0.661 |
|
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